Journal of Cell Biology 1995: Vol 129 Table of Contents

11 Pages·1995·0.48 MB·English

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The Journal of
B
Volume 129, 1995
S/TfrX- Editor-in-Chief
f
O Rocfcefe//cr jm
• B[Universit^J^ ASCB
0\ iqoi Norton B. Gilula
Associate Editors
Edited in cooperation with
Richard G. W. Anderson Elaine Fuchs
The American Society
Don W. Cleveland Randy Schekman
for Cell Biology
Werner Franke Kenneth M. Yamada
Published semimonthly by
The Rockefeller University Press
Editorial Board
Copyediting and Production
Suzanne M. Runyan,
Linda Thrasybule, and
Vann Bennett Ira Mellman
Davide R. Dickson
Paul Bomstein Ron Milligan
Marianne Bronner-Fraser Timothy J. Mitchison
Eric J. Brown Andrew Murray
Graham Carpenter W. James Nelson
Nam-Hai Chua Walter Neupert
John Cooper Eric N. Olsen
Bruce Cunningham Suzanne PfefFer
Caroline Damsky Tom A. Rapoport
Scott Emr Louis F. Reichardt
Harold P. Erickson Daniel B. Rifkin
Larry Gerace Mark Rose
Mary Jane Gething Richard Rotundo
Hans Geuze Richard Scheller
Larry Goldstein Sandra Schmid
Alan Hall Victor Small
Alan F. Horwitz Paul W. Sternberg
Hynda Kleinman Murray Stewart
Susan Lindquist Ron Vale
Joan Massague Klaus Von der Mark
Frederick Maxfield Frank S. Walsh
Jacopo Meldolesi Helen Lu Yin
Copyright © 1995 by The Rockefeller University Press
Contents:
Volume 129, Number 1, April 1995
1 An analysis of the regulation of DNA synthesis 121 Cholesterol depletion and modification of
by cdk2, Cipl, and licensing factor. COOH-termin^ targeting sequence of the
H. Yan and J. Newport prion protein inhibit formation of the scrapie
isoform.
17 Analysis of nuclear lamin isoprenylation in
A. Taraboulos, M. Scott, A. Semenov, D. Avraham,
Xenopus oocytes: Isoprenylation of lamin B3 L. Laszlo, and S. B. Prusiner
precedes its uptake into the nucleus.
133 Sequestration of acetylated LDL and
I. Firmbach-Kraft and R. Stick
cholesterol crystals by human
25 Mas37p, a novel receptor subunit for protein monocyte-derived macrophages.
import into mitochondria. H. S. Kruth, S. I. Skarlatos, K. Lilly, J. Chang,
and 1. Ifrim
S. Gratzer, T. Lithgow, R. E. Bauer, E Lamping,
F. Paltauf, S. D. Kohlwein, V. Haucke, T. Junne, 147 Effects of CapG overexpression on
G. Schatz, and M. Horst
agonist-induced motility and second messenger
35 Golgi and vacuolar membrane proteins reach generation.
the vacuole in vpsl mutant yeast cells via the H.-Q. Sun, K. Kwiatkowska, D. C. Wooten,
plasma membrane. and H. L. Yin
S. F. Nothwehr, E. Conibear, and T. H. Stevens 157 KIF2 is a new microtubule-based anterograde
motor that transports membranous organelles
47 Recruitment of epidermal growth factor
distinct from those carried by kinesin heavy
receptors into coated pits requires their
chain or KIF3A/B.
activated tyrosine kinase.
Y. Noda, R. Sato-Yoshitake, S. Kondo, M. Nangaku,
C. Lamaze and S. L. Schmid and N. Hirokawa
55 Endocytosis of interleukin 2 receptors in 169 The 78,000 M, intermediate chain of
human T lymphocytes: Distinct intracellular Chlamydomonas outer arm dynein is a
localization and fate of the receptor a, jS, y WD-repeat protein required for arm assembly.
chains.
C. G. Wilkerson, S. M. King, A. Koutoulis,
A. H6mar, A. Subtil, M. Lieb, E. Morelon, G. J. Pazour, and G. B. Witman
R. Hellio, and A. Dautry-Varsat
179 A talin homologue of Dictyostelium rapidly
65 PEBl (PAS7) in Saccharomyces cerevisiae assembles at the leading edge of cells in
encodes a hydrophilic, intra-peroxisomal response to chemoattractant.
protein that is a member of the WD repeat M. Kreitmeier, G. Gerisch, C. Heizer,
family and is essential for the import of and A. Muller-Taubenberger
thiolase into peroxisomes.
189 Novel E-cadherin-mediated adhesion in
J. W. Zhang and R B. Lazarow peripheral nerve: Schwann cell architecture is
stabilized by autotypic adherens junctions.
81 Targeting of Salmonella typhimurium to
vesicles containing lysosomal membrane A. M. Fannon, D. L. Sherman, G. Ilyina-Gragerova,
P. J. Brophy, V. L. Friedrich Jr., and D. R. Colman
glycoproteins bypasses compartments with
mannose 6-phosphate receptors. 203 The molecular organization of endothelial cell
F. Garcia-del Pbrtillo and B. B. Finlay to cell junctions: Differential association of
plakoglobin, /3-catenin, and a-catenin with
99 The exocytotic fusion pore of small granules vascular endothelial cadherin (VE-cadherin).
has a conductance similar to an ion channel.
M. G. Lampugnani, M. Corada, L. Caveda,
K. Lollike, N. Borregaard, and M. Lindau F. Breviario, O. Ayalon, B. Geiger, and E. Dejana
105 rbSeclA and B colocalize with syntaxin 1 219 Cellubrevin and synaptobrevins: Similar
and SNAP-25 throughout the axon, but are not subcellular localization and biochemical
in a stable complex with syntaxin. properties in PC12 cells.
E. P. Garcia, P. S. McPherson, T. J. Chilcote, T. J. Chilcote, T. Galli, O. Mundigl, L. Edelmann,
K. Takei, and P. De Camilli P. S. McPherson, K. Takei, and P. De Camilli
233 Differential modulation of cell phenotype by 255 Episialin (MUCl) overexpression inhibits
different molecular weight forms of basic integrin-mediated cell adhesion to extracellular
fibroblast growth factor: Possible intracellular matrix components.
signaling by the high molecular weight forms.
J. Wesseling, S. W. van der Valk, H. L. Vos,
A. Bikfalvi, S. Klein, G. Pintucci, N. Quarto, A. Sonnenberg, and J. Hilkens
P. Mignatti, and D. B. Rifkin
267 Midkine (MK), a Heparin-binding
growth/differentiation factor, is regulated by
retinoic acid and epithelial—mesenchymal
interactions in the developing mouse tooth,
245 Involvement of pRB family in and affects cell proliferation and
TGF/3-dependent epithelial cell hypertrophy. morphogenesis.
H. A. Franch, J. W. Shay, R. J. Alpem, T. A. Mitsiadis, T. Muramatsu, H. Muramatsu,
and P. A. Preisig and I. Thesleff
Volume 129, Number 2, April 1995
287 Transcription-dependent redistribution of the 367 Cytoskeletal rearrangements and functional
large subunit of RNA polymerase II to discrete role of T-plastin during entry of Shigella
nuclear domains. flexneri into HeLa cells.
D. B. Bregman, L. Du, S. van der Zee, T. Adam, M. Arpin, M.-C. Prdvost, P. Gounon,
and S. L. Warren and P. J. Sansonetti
299 Enzymatic product formation impairs both the 383 Myosin light chain 3F regulatory sequences
chloroplast receptor-binding function as well confer regionalized cardiac and skeletal muscle
as translocation competence of the NADPH: expression in transgenic mice.
Protochlorophyllide oxidoreductase, a
R. Kelly, S., Alonso, S. Tajbakhsh, G. Cossu,
nuclear-encoded plastid precursor protein. and M. Buckingham
S. Reinbothe, C. Reinbothe, S. Runge, and K. Apel
397 Differential methylation and altered
309 The capacity to retrieve escaped ER proteins conformation of cytopklasmic and nuclear
extends to the trans-most cistema of the Golgi forms of protein phosphatase 2A during cell
stack. cycle progression.
G. Miesenbock and J. E. Rothman P. Throwski, A. Fernandez, B. Favre, N. J. C. Lamb,
and B. A. Hemmings
321 Vesicle-mediated protein transport: Regulatory
interactions between the VpslS protein kinase 411 Two distinct functions of the carboxyl-terminal
and the Vps34 Ptdins 3-kinase essential for tail domain of NF-M upon neurofilament
protein sorting to the vacuole in yeast. assembly: Cross-bridge formation and
J. H. Stack, D. B. DeWald, K. Takegawa, longitudinal elongation of filaments.
and S. D. Emr
T. Nakagawa, J. Chen, Z. Zhang, Y. Kanai,
and N. Hirokawa
335 The urokinase-type plasminogen activator
receptor, a GPI-linked protein, is localized in 431 Trafficking of cell surface /3-amyloid precursor
caveolae. protein: Retrograde and transcytotic transport
A. Stahl and B. M. Mueller in cultured neurons.
345 Pmp27 promotes peroxisomal proliferation. T. Yamazaki, D. J. Selkoe, and E. H. Koo
P. A. Marshall, Y. I. Krimkevich, R. H. Lark, 443 Transforming growth factor-/31 regulates
J. M. Dyer, M. Veenhuis, and J. M. Goodman
axon/schwann cell interactions.
357 Specific receptor detection by a functional S. Einheber, M.-J. Hannocks, C. N. Metz,
keratinocyte growth factor-immunoglobulin D. B. Rifkin, and J. L. Salzer
chimera.
459 Autocrine motility factor receptor is a marker
W. J. LaRochelle, O. R. Dirsch, P. W. Finch, for a distinct membranous tubular organelle.
H. -G. Cheon, M. May, C. Marchese,
J. H. Pierce, and S. A. Aaronson N. Benlimame, D. Simard, and 1. R. Nabi
iv
473 A recombinant tail-less integrin 04 subunit 521 Antibodies against domain E3 of laminin-1
disrupts hemidesmosomes, but does not and integrin a6 subunit perturb branching
suppress a6/34-mediated cell adhesion to epithelial morphogenesis of submandibular
laminins. gland, but by different modes.
L. Spinardi, S. Einheber, T. Cullen, T. A. Milner, Y. Kadpya, K. Kadpya, M. Durbeej, K. Holmvall,
and F. G. Giancotti L. Soroidn, and R Ekblom
489 In vivo analysis of cadherin function in the
mouse intestinal epithelium: Essential roles in
adhesion, maintenance of differentiation, and
regulation of programmed cell death. 535 Molecular cloning of chick /3-tectorin, an
M. L. Hermiston and J. I. Gordon extracellular matrix molecule of the inner ear.
R. Killick, P. K. Legan, C. Malenczak,
507 Plasticity in epithelial cell phenotype:
and G. P. Richardson
Modulation by expression of different cadherin
cell adhesion molecules.
J. A. Marrs, C. Andersson-Fisone, M. C. Jeong,
L. Cohen-Gould, C. Zurzolo, I. R. Nabi,
E. Rodriguez-Boulan, and W. J. Nelson 549 ADDITIONS AND CORRECTIONS
Volume 129, Number 3, May 1995
551 A nuclear localization domain in the hnRNP 659 Molecular architecture of membranes involved
A1 protein. in excitation-contraction coupling of cardiac
H. Siomi and G. Drey fuss muscle.
X.-H. Sun, F. Protasi, M. Takahashi, H. Takeshima,
561 A possible mechanism for the inhibition of
D. G., Ferguson, and C. Franzini-Armstrong
ribosomal RNA gene transcription during
mitosis. 673 Immunolocalization of sarcolemmal
dihydropyridine receptor and sarcoplasmic
D. Weisenberger and U. Scheer
reticular triadin and ryanodine receptor in
577 Reconstitution of vesiculated Golgi membranes rabbit ventricle and atrium.
into stacks of cistemae: Requirement of NSF
S. Lewis Carl, K. Felix, A. H. Caswell,
in stack formation. N. R. Brandt, W. J. Ball Jr., P. L. Vaghy,
U. Acharya, J. M. McCalfery, R. Jacobs, G. Meissner, and D. G. Ferguson
and V. Malhotra
683 Mechanisms of thin filament assembly in
591 Laminin mediates tissue-specific gene embryonic chick cardiac myocytes:
expression in mammary epithelia. Tropomodulin requires tropomyosin for
assembly.
C. H. Streuli, C. Schmidhauser, N. Bailey,
P. Yurchenco, A. P. N. Skubitz, C. Roskelley, C. C. Gregorio and V. M. Fowler
and M. J. Bissell
697 Forced expression of chimeric human fibroblast
605 Reassembly of Golgi stacks from mitotic Golgi tropomyosin mutants affects cytokinesis.
fragments in a cell-free system.
K. S. Warren, J. L.-C. Lin, J. P. McDermott,
C. Rabouille, T. Misteli, R. Watson, and G. Warren and J. J.-C. Lin
619 Glycolipid-anchored proteins in neuroblastoma 709 The Drosophila kinesin-like protein KLP3A is
cells form detergent-resistant complexes a midbody component required for central
without caveolin. spindle assembly and initiation of cytokinesis.
A. Gorodinsky and D. A. Harris B. C. Williams, M. F. Riedy, E. V. Williams,
M. Gatti, and M. L. Goldberg
629 'Vbast Gaalp is required for attachment of a
completed GPI anchor onto proteins. 725 The Drosophila cell cycle gene fizzy is required
for normal degradation of cyclins A and B
D. Hamburger, M. Egerton, and H. Riezman
during mitosis and has homology to the
641 Insulin-sensitive targeting of the GLUT4 CDC20 gene of Saccharomyces cerevisiae.
glucose transporter in L6 myoblasts is
1. A. Dawson, S. Roth, and S. Artavanis-Tsakonas
conferred by its COOH-terminal cytoplasmic
tail. 739 A cell cycle checkpoint monitors cell
morphogenesis in budding yeast.
P. M. Haney, M. A. Levy, M. S. Strube,
and M. Mueckler D. J. Lew and S. 1. Reed
751 Patterns of bud-site selection in the yeast 831 Integrin-dependent translocation of
Saccharomyces cerevisiae. phosphoinositide 3-kinase to the cytoskeleton
J. Chant and J. R. Pringle of thrombin-activated platelets involves specific
interactions of p85a with actin filaments and
767 Role of Bud3p in producing the axial budding focal adhesion kinase.
pattern of yeast.
C. Guinebault, B. Payrastre, C. Racaud-Sultan,
J. Chant, M. Mischke, E. Mitchell, I. Herskowitz, H. Mazarguil, M. Breton, G. Mauco, M. Plantavid,
and J. R. Pringle and H. Chap
779 Cells differentiating into neuroectoderm 843 Keratinocyte growth factor is a bifiinctional
regulator of HPV16 DNA-immortalized cervical
undergo apoptosis in the absence of functional
epithelial cells.
retinoblastoma family proteins.
J. Zheng, O. Saksela, S. Matikainen, and A. Vaheri
R. S. Slack, I. S. Skeijanc, B. Lach, J. Craig,
K. Jatdine, and M. W. McBumey
853 Transforming growth factor-|31 modulates /31
and 05 integrin receptors and induces the
789 Calcitonin gene-related peptide promotes
de novo expression of the crvjSb heterodimer in
Schwann cell proliferation.
normal human keratinocytes: Implications for
L. Cheng, M. Khan, and A. W. Mudge
wound healing.
797 Ca^^ waves in PC12 neurites: A bidirectional, G. Zambruno, P. C. Marchisio, A. Marconi,
receptor-oriented form of Ca^^ signaling. C. Vaschieri, A. Melchiori, A. Giannetti,
and M. De Luca
P. Lorenzon, D. Zacchetti, E Codazzi, G. Fumagalli,
J. Meldolesi, and E Grohovaz 867 Cooperative signaling by aS0l and a4|81
integrins regulates metalloproteinase gene
805 Specific permeability and selective
expression in fibroblasts adhering to fibronectin
formation of gap junction channels in
P. Huhtala, M. J. Humphries, J. B. McCarthy,
connexin-transfected HeLa cells.
P. M. Tremble, Z. Werb, and C. H. Damsky
C. Elfgang, R. Eckert, H. Lichtenberg-Frate,
A. Butterweck, O. Traub, R. A. Klein, D. E Hiilser, 881 Transglutaminase-catalyzed matrix
and K. Willecke cross-linking in differentiating cartilage:
Identification of osteonectin as a major
819 A novel mammalian myosin I from rat with an
glutaminyl substrate.
SH3 domain localizes to Con A-inducible,
F-actin-rich structures at cell-cell contacts. D. Aeschlimann, O. Kaupp, and M. Paulsson
H.-E. Stoffler, C. Ruppert, J. Reinhard, and M. Bahler 893 ADDITIONS AND CORRECTIONS
Volume 129, Number 4, May 1995
Mini-review 939 A conditional allele of the novel
895 Endothelial receptor tyrosine kinases involved repeat-containing yeast nucleoporin
in angiogenesis. RAT7 / NUP159 causes both rapid cessation of
mRNA export and reversible clustering of
T. Mustonen and K. Alitalo
nuclear pore complexes.
Regular Articles
L. C. Gorsch, T. C. Dockendorff, and C. N. Cole
899 A conserved epitope on a subset of SR proteins
defines a larger family of pre-mRNA splicing
factors. 957 Stage- and ribosome-specific alterations in
K. M. Neugebauer, J. A. Stolk, and M. B. Roth nascent chain-Sec61p interactions accompany
translocation across the ER membrane.
909 The carboxy termini of Sir4 and Rapl affect
Sir3 localization: Evidence for a C. V. Nicchitta, E. C. Murphy III, R. Haynes,
and G. S. Shelness
multicomponent complex required for yeast
telomeric silencing.
M. Cockell, F. Palladino, T. Laroche, G. Kyrion,
971 Steric masking of a dilysine endoplasmic
C. Liu, A. J. Lustig, and S. M. Gasser
reticulum retention motif during assembly of
925 Identification of NTF2, a cytosolic factor for the human high affinity receptor for
nuclear import that interacts with nuclear pore immunoglobulin E.
complex protein p62.
E Letoumeur, S. Hennecke, C. Demollifere,
B. M. Paschal and L. Gerace and P. Cosson
979 A yeast DnaJ homologue, Scjlp, can function 1081 An ankyrin-related gene iunc-44) is necessary
in the endoplasmic reticulum with BiP/Kar2p for proper axonal guidance in Caenorhabditis
via a conserved domain that specifies elegans.
interactions with Hsp70s. A. J. Otsuka, R. Franco, B. Yang, K.-H. Shim,
G. Schlenstedt, S. Harris, B. Risse, R. Lill, L. Z. Tang, Y. Y. Zhang, P. Boontrakulpoontawee,
and R A. Silver A. Jeyapr^sh, E. Hedgecock, V. I. Wheaton,
and A. Sobery
989 Molecular size-fractionation during 1093 EHstribution of a-dystroglycan during
endocytosis in macrophages. embryonic nerve-muscle synaptogenesis.
E. P. Berthiaume, C. Medina, and J. A. Swanson M. W. Cohen, C. Jacobson, E. W. Godfrey,
K. P. Campbell, and S. Carbonetto
999 Expression and compartmentalization of 1103 R-Ras promotes apoptosis caused by growth
caveolin in adipose cells; Coordinate regulation factor deprivation via a bcl-2 suppressible
with and structural segregation from GLUT4. mechanism.
K. V. Kandror, J. M. Stephens, and P. R Pilch H.-G. Wang, J. A. Millan, A. D. Cox,
C. J. Der, U. R. Rapp, T. Beck, H. Zha,
and J. C. Reed
1007 Molecular dissection of radixin; Distinct and
1115 Extracellular matrix regulates whey acidic
interdependent functions of the amino- and
protein gene expression by suppression of
carboxy-terminal domains.
TGF-a in mouse mammary epithelial cells:
M. D. Henry, C. Gonzalez Agosti, and F. Solomon Studies in culture and in transgenic mice.
C. Q. Lin, P. J. Dempsey, R. J. Colfey,
1023 Spnr, a murine RNA-binding protein that is
and M. J. Bissell
localized to cytoplasmic microtubules.
1127 Characterization of /3pat-3 heterodimers, a
J. M. Schumacher, K. Lee, S. Edelhoff,
and R. E. Braun family of essential integrin receptors in
C. elegans.
1033 The product of the spindle formation gene S. N. Gettner, C. Kenyon, and L. F. Reichardt
sadl* associates with the fission yeast spindle
1143 A peptide derived from the intercellular
pole body and is essential for viability.
adhesion molecule-2 regulates the avidity of
I. Hagan and M. Yanagida the leukocyte integrins CDllb/CD18 and
CDllc/CD18.
1049 Characterization of a minus end-directed
R. Li, J. Xie, C. Kant or, V. Koistinen, D. C. Altieri,
kinesin-like motor protein from cultured P. Nortamo, and C. G. Gahmberg
mammalian cells.
1155 The cytoplasmic domain of L-selectin interacts
R. Kuriyama, M. Kofron, R. Essner, T. Kato,
with cytoskeletal proteins via a-actinin:
S. Dragas-Granoic, C. K. Omoto, and A. Khodjakov
Receptor positioning in microvilli does not
require interaction with a-actinin.
1061 Is the cell division cycle gated by a circadian
clock? The case of Chlamydomonas reinhardtii. F. M. Pavalko, D. M. Walker, L. Graham,
M. Goheen, C. M. Doerschuk, and G. S. Kansas
K. Goto and C. Johnson
1165 Developmental expression of fibrillin genes
1071 Cell contacts orient some cell division axes in suggests heterogeneity of extracellular
the Caenorhabditis elegans embryo. microfibrils.
B. Goldstein H. Zhang, W. Hu, and F. Ramirez
Volume 129, Numbers, June 1995
Mini-review Regular Articles
1177 The many faces of hepatocyte growth factor: 1181 A perinucleolar compartment contains several
From hepatopoiesis to hematopoiesis. RNA polymerase 111 transcripts as well as the
polypyrimidine tract-binding protein, hnRNP I.
R. Zarnegar and G. K. Michalopoulos
A. G. Matera, M. R. Frey, K. Margelot,
and S. L. Wolin
vii
1195 Microinjection of mitotic cells with the 3F3/2 1329 The basal keratin network of stratified squamous
anti-phosphoepitope antibody delays the onset epithelia: Defining K15 function in the absence
of anaphase. of K14.
M. S. Campbell and G. J. Gorbsky C. Lloyd, Q.-C. Yu, J. Cheng, K. Turksen,
L. Degenstein, E. Hutton, and E. Fuchs
1205 Structural interaction between the nuclear
pore complex and a specific translocating 1345 Regulation of a muscle-specific transgene by
RNP particle. retinoic acid.
H. Mehlin, B. Daneholt, and U. Skoglund Y. Xiao, U. Grieshammer, and N. Rosenthal
1217 Efficient endosomal localization of major
1355 Calsensin: A novel calcium-binding protein
histocompatibility complex class Il-invariant
expressed in a subset of peripheral leech neurons
chain complexes requires multimerization of the
fasciculating in a single axon tract.
invariant chain targeting sequence.
K. K. Briggs, A. J. Silvers, K. M. Johansen,
L. S. Arneson and J. Miller
and J. Johansen
1229 “Synchronized” endocytosis and intracellular
1363 bcl-2 overexpression inhibits cell death and
sorting in alveolar macrophages: The early
promotes the morphogenesis, but not
sorting endosome is a transient organelle.
tumorigenesis of human mammary
D. M. Ward, C. M. Perou, M. Lloyd, and J. Kaplan
epithelial cells.
1241 Apical and basolateral coated pits of MDCK P. J. Lu, Q. L. Lu, A. Rughetti,
cells differ in their rates of maturation into and J. Taylor-Papadimitriou
coated vesicles, but not in the ability to
distinguish between mutant hemagglutinin 1379 The cadherin-binding specificities of B-cadherin
proteins with different internalization signals. and LCAM.
H. Y. Naim, D. T. Dodds, C. B. Brewer, C. Murphy-Erdosh, C. K. Yoshida, N. Paradies,
and M. G. Roth and L. F. Reichardt
1251 A density-sensing factor regulates signal
1391 The interaction of the retina cell surface
transduction in Dictyostelium.
N-acetylgalactosaminylphosphotransferase
I. S. Yuen, R. Jain, J. D. Bishop, D. F. Lindsey, W. J. with an endogenous proteoglycan ligand results
Deery, P. J. M. Van Haastert, and R. H. Gomer in inhibition of cadherin-mediated adhesion.
1263 A trypanosome-soluble factor induces IP3 J. Balsamo, H. Ernst, M. K. B. Zanin, S. Hoffman,
formation, intracellular Ca^'*' mobilization and and J. Lilien
microfilament rearrangement in host cells.
1403 Identification of the low density lipoprotein
A. Rodriguez, M. G. Rioult, A. Ora,
and N. W. Andrews receptor-related protein (LRP) as an endocytic
receptor for thrombospondin-1.
1275 Actin filament organization in the fish keratocyte
S. Godyna, G. Liau, 1. Popa, S. Stefansson,
lamellipodium.
and W. S. Argraves
J. V. Small, M. Herzog, and K. Anderson
1411 Hepatocyte growth factor/scatter factor
1287 The impact of chromosomes and centrosomes on
modulates cell motility, proliferation, and
spindle assembly as observed in living cells.
proteoglycan synthesis of chondrocytes.
D. Zhang and R. B. Nicklas
T. Takebayashi, M. Iwamoto, A. Jikko,
1301 Acetylation of lysine 40 in a-tubulin is not T. Matsumura, M. Enomoto-Iwamoto, F. Myoukai,
essential in Tetrahymena thermophilcu E. Koyama, T. Yamaai, K. Matsumoto, T. Nakamura,
K. Kurisu, and S. Noji
J. Gaertig, M. A. Cruz, J. Bowen, L. Gu,
D. G. Pennock, and M. A. Gorovsky
1421 Separate cts-acting DNA elements of the
1311 Structure of growing microtubule ends: mouse pro-al(l) collagen promoter direct
Two-dimensional sheets close into tubes at expression of reporter genes to different type I
variable rates. collagen-producing cells in transgenic mice.
D. Chretien, S. D. Fuller, and E. Karsenti J. Rossert, H. Eberspaecher, and B. de Crombrugghe
viii
Volume 129, Number 6, June 1995
1433 BM28, a human member of the MCM2-3-5 1575 The 95F unconventional myosin is required for
family, is displaced from chromatin during DNA proper organization of the Drosophila syncytial
replication. blastoderm.
I. T. Todorov, A. Attaran, and S. E. Kearsey V. Mermall and K. G. Miller
1447 Nuclear envelope breakdown is under nuclear 1589 Actin polymerization and intracellular solvent
not cytoplasmic control in sea urchin zygotes. flow in cell surface blebbing.
G. Sluder, E. A. Thompson, C. L. Rieder, C. C. Cunningham
and F. J. Miller
1601 Three-dimensional ultrastructural analysis of
1459 Nuclear pore complex assembly studied with a the Saccharomyces cerevisiae mitotic spindle.
biochemical assay for annulate lamellae
M. Winey, C. L. Mamay, E. T. O’Toole,
formation. D. N. Mastronarde, T. H. Giddings, Jr.,
E. Meier, B. R. Miller, and D. J. Forbes K. L. McDonald, and J. Richard McIntosh
1473 The overgrown hematopoietic organs-31 tumor 1617 Cell cycle regulation of the activity and
suppressor gene of Drosophila encodes an subcellular localization of PLKl, a human
Importin-Mke protein accumulating in the protein kinase implicated in mitotic spindle
nucleus at the onset of mitosis. inunction.
1. Torok, D. Strand, R. Schmitt, G. Tick, T. Tordk, R. M. Golsteyn, K. E. Mundt, A. M. Fry,
1. Kiss, and B. M. Mechler and E. A. Nigg
1491 Pendulin, a Drosophila protein with cell 1629 Overexpression of the human NFM subunit in
cycle-dependent nuclear localization, is required transgenic mice modifies the level of endogenous
for normal cell proliferation. NFL and the phosphorylation state of NFH
subunits.
P. Kiissel and M. Frasch
P.-H. Tu, G. Elder, R. A. Lazzarini, D. Nelson,
1509 Oligomerized transferrin receptors are J. Q. Trojanowski, and V. M.-Y. Lee
selectively retained by a lumenal sorting signal
1641 7B2 facilitates the maturation of proPC2 in
in a long-lived endocytic recycling compartment.
neuroendocrine cells and is required for the
E. W. Marsh, P. L. Leopold, N. L. Jones,
expression of enzymatic activity.
and F. R. Maxfield
X. Zhu and I. Lindberg
1523 Insulin stimulates the tyrosine phosphorylation
of caveolin. 1651 Increased intracellular Ca^'*’ selectively
suppresses IL-l-induced NO production by
C. C. Mastick, M. J. Brady, and A. R. Saltiel
reducing iNOS mRNA stability.
1533 Pseudomonas exotoxin-mediated selection yields
Y. Geng and M. Lotz
cells with altered expression of low-density
lipoprotein receptor-related protein. 1659 Chemoattractant and GTPyS-mediated
stimulation of adenylyl cyclase in Dictyostelium
D. J. FitzGerald, C. M. Fryling, A. Zdanovsky,
C. B. Saelinger, M. Kounnas, J. A. Winkles, requires translocation of CRAC to membranes.
D. Strickland, and S. Leppla P. J. Lilly and P. N. Devreotes
1543 Oligomerization of epidermal growth factor
1667 The G protein ^ subunit is essential for multiple
receptors on A431 cells studied by time-resolved
responses to chemoattractants in Dictyostelium.
fluorescence imaging microscopy. A
L. Wu, R. Valkema, P. J. M. Van Haastert,
stereochemical model for tyrosine kinase
and P. N. Devreotes
receptor activation.
T. W. J. Gadella, Jr. and T. M. Jovin 1677 The human E48 antigen, highly homologous
to the murine Ly-6 antigen ThB, is a
1559 Barriers for lateral diffusion of transferrin GPI-anchored molecule apparently involved
receptor in the plasma membrane as in keratinocyte cell-cell adhesion.
characterized by receptor dragging by laser
R. H. Brakenhoff, M. Gerretsen, E. M. C. Knippels,
tweezers: Fence versus tether.
M. van Dijk, H. van Essen, D. O. Weghuis,
Y. Sako and A. Kusumi R. J. Sinke, G. B. Snow, and G. A. M. S. van Dongen
IX
1691 Membrane-anchored heparin-binding EGF-like 1721 ADDITIONS AND CORRECTIONS
growth factor (HB-EGF) and diphtheria toxin
1723 AUTHOR INDEX FOR VOLUME 129
receptor-associated protein (DRAP27)/CD9
form a complex with integrin ajpi at cell-cell 1733 SUBJECT INDEX FOR VOLUME 129
contact sites.
1743 ACKNOWLEDGMENT
K. Nakamura, R. Iwamoto, and E. Mekada
1707 Components of the nuclear signaling cascade
that regulate collagenase gene expression in
response to integrin-derived signals.
P. Tremble, C. H. Damsky, and Z. Werb