Journal of Cell Biology 1993: Vol 123 Table of Contents

11 Pages·1993·0.53 MB·English

Norton B. Gilula
ASCB Associate Editors
Richard G. W. Anderson Elaine Fuchs
Don W. Cleveland Randy Schekman
Werner Franke Kenneth M. Yamada
Edited in cooperation with
The American Society
for Cell Biology Editorial Board
Published semimonthly by
The Rockefeller University Press
Vann Bennett Jacopo Meldolesi
Copyediting and Production Helen Blau Ira Mellman
Suzanne M. Runyan, Graham Carpenter Ron Milligan
Robert J. O’Donnell, and Nam-Hai Chua Timothy J. Mitchison
Linda Thrasybule John Cooper Andrew Murray
Sara Courtneidge W. James Nelson
Bruce Cunningham Walter Neupert
Caroline Damsky Bjorn Olsen
Scott Enw Suzanne PfefFer
Harold P. Erickson Thomas Pollard
Susan M. Gasser Tom A. Rapoport
Larry Gerace Louis F. Reichardt
Mary Jane Gething Daniel B. Rifkin
Larry Goldstein Mark Rose
Corey S. Goodman Richard Rotundo
Alan F. Horwitz Richard Scheller
R. L. Juliano Victor Small
Judith Kimble Murray Stewart
Richard Klausner Ron Vale
Hynda Kleinman Klaus Von der Mark
Susan Lindquist Frank S. Walsh
Joan Massague Helen Lu Yin
Frederick Maxfield

Contents:
Volume 123, Number 1, October 1993
1 Mini-review 119 Presequence and mature part of preproteins
Focusing on unpolymerized actin. stron^y influence the dependence of
mitochondrial protein import on heat shock
M. Fechheimer and S. H. Zigmond
protein 70 in the matrix.
Regular Articles
W. Voos, B. D. Gambill, B. Guiard, N. Planner,
7 Nuclear events of apoptosis in vitro in cell-free and E. A. Craig
mitotic extracts: A model system for analysis
of the active phase of apoptosis. 127 Exofacial epitope-tagged glucose transporter
Y. A. Lazebnik, S. Cole, C. A. Cooke, W. G. Nelson, chimeras reveal COOH-terminal sequences
and W. C. Eamshaw governing cellular localization.
23 The actin-binding protein comitin (p24) is a M. P. Czech, A. Chawla, C.-W. Woon, J. Buxton,
M. Armoni, W. Tang, M. Joly, and S. Corvera
component of the Golgi apparatus.
O. H. Weiner, J. Murphy, G. Griffiths, M. Schleicher,
137 Identification of the carboxy-terminus as
and A. A. Noegel
important for the isoform-specific subcellular
35 RabS, a small GTPase involved in vesicular targeting of glucose transporter proteins.
traflSc between the TGN and the basolateral K. J. Verhey, S. F. Hausdorff, and M. J. Bimbaum
plasma membrane.
L. A. Huber, S. Pimplikar, R. G. Parton, H. Virta, 149 Distinguishing roles of the
M. Zerial, and K. Simons
membrane-cytoskeleton and cadherin mediated
47 Protein transport to the dendritic plasma cell-cell adhesion in generating different
membrane of cultured neurons is regulated by Na^,K^-ATPase distributions in
rabSp. polarized epithelia.
L. A. Huber, M. J. de Hoop, P. Dupree, M. Zerial, J. A. Marrs, E. W. Napolitano, C. Murphy-Erdosh,
K. Simons, and C. Dotti R. W. M^s, L. F. Reichardt, and W. J. Nelson
57 Cholesterol is required in the exit pathway of
165 Isoform-specific 3'-untranslated sequences sort
Semliki Forest virus.
a-cardiac and |3-cytoplasmic actin messenger
M. T. Marquardt, T. Phalen, and M. Kielian
RNAs to different cytoplasmic compartments.
67 Assembly and targeting of adaptin chimeras in E. H. Kislauskis, Z. Li, R. H. Singer,
transfected cells. and K. L. Taneja
M. S. Robinson
173 Localization and dynamics of noniilamentous
79 Redistribution of clathrin-coated vesicle
actin in cultured cells.
adaptor complexes during adipocytic
differentiation of 3T3-L1 cells. L. -G. Cao, D. J. Fishkind, and Y.-L. Wang
R. Chakrabarti, M. Joly, and S. Corvera
183 Assembly of flagellar radial spoke proteins in
89 Molecules internalized clathrin-independent Chlamydomonas’. identification of the axoneme
endocytosis are delivered to endosomes binding domain of radial spoke protein 3.
containing transferrin receptors.
D. R. Diener, L. H. Ang, and J. L. Rosenbaum
S. H. Hansen, K. Sandvig, and B. van Deurs
99 Mannose 6-phosphate-independent targeting of
191 The relationship between cell size and cell fate
lysosomal enzymes in I-cell disease B in Volvox carteri.
lymphoblasts.
M. M. Kirk, A. Ransick, S. E. McRae,
J. N. Glickman and S. Komfeld and D. L. Kirk
109 A dual role for mitochondrial heat shock
protein 70 in membrane translocation of 209 Tissue polarity genes of Drosophila regulate
preproteins. the subcellular location for prehair initiation in
pupal wing cells.
B. D. Gambill, W. Voos, P. J. Kang, B. Miao,
T. Danger, E. A. Craig, and N. Pfanner L. L. Wong and P. N. Adler
iii
223 Scatter factor/hepatocyte growth factor and 245 Mutation of putative divalent cation sites in
its receptor, the c-met tyrosine kinase, can the a* subunit of the integrin VLA-4: Distinct
mediate a signal exchange between effects on adhesion to CSl/fibronectin,
mesenchyme and epithelia during mouse VCAM-1, and invasin.
development.
A. Masumoto and M. E. Hemler
E. Sonnenbeig, D. Meyer, K. M. Weidner,
255 Genetic identification, sequence, and
and C. Birchmeier
alternative splicing of the Caenorhabditis
237 Neurons regulate Schwann cell genes by elegans a2(IV) collagen gene.
difiusible molecules.
M. H. Sibley, J. J. Johnson, C. C. Mello,
L. M. Bolin and E. M. Shooter and J. M. Kramer
Volume 123, Number 2, October 1993
Mini-review 357 Identification and molecular characterization
269 RNA on the move: The mRNA localization of E-MAP-115, a novel microtubule-associated
pathway. protein predominantly expressed in epithelial
cells.
J. E. Wilhelm and R. D. Vale
D. Masson and T. E. Kreis
Regular Articles
275 A temperature-sensitive NUP116 null mutant 373 Molecular analysis of the INCENPs (inner
forms a nuclear envelope seal over the yeast centromere proteins): Separate domains are
nuclear pore complex thereby blocking required for association with microtubules
nucleocytoplasmic traffic. during interphase and with the central spindle
during anaphase.
S. R. Wente and G. Blobel
A. M. Mackay, D. M. Eckley, C. Chue,
285 Proteolytic cleavage of haptoglobin occurs in a and W. C. Eamshaw
subcompartment of the endoplasmic reticulum:
387 MIF2 is required for mitotic spindle integrity
Evidence from membrane fusion in vitro.
during anaphase spindle elongation in
M. Wassler and E. Fries Saccharomyces cerevisiae.
293 Assembly of the tight junction: The role of M. T. Brown, L. Goetsch, and L. H. Hartwell
diacylglycerol.
M. S. Baida, L. Gonzalez-Mariscal, K. Matter, 405 The calcium-binding protein cell division cycle
M. Cereijido, and J. M. Anderson 31 of Saccharomyces cerevisiae is a component
303 Thick filament substructures in Caenorhabditis of the half bridge of the spindle pole body.
elegans: Evidence for two populations of A. Spang, I. Courtney, U. Fackler, M. Matzner,
paramyosin. and E. Schiebel
P. R. Deitiker and H. F. Epstein
417 Depletion of 43-kD growth-associated
313 Three-dimensional reconstruction of protein in primary sensory neurons leads to
caldesmon-containing smooth muscle thin diminished formation and spreading of
filaments. growth cones.
P. Vibert, R. Craig, and W. Lehman L. Aigner and P. Caroni
323 Contractile activity and cell-cell contact
431 Transport and localization of exogenous myelin
regulate myofibrillar organization in cultured
basic protein mRNA microinjected into
cardiac myocytes.
oligodendrocytes.
D. G. Simpson, M. L. Decker, W. A. Clark,
K. Ainger, D. Avossa, F. Morgan, S. J. Hill, C. Barry,
and R. S. Decker
E. Barbarese, and J. H. Carson
337 A 13-A map of the actin-scruin filament from
the limulus acrosomal process. 443 A myelin proteolipid protein-lacZ fusion
protein is developmentally regulated and
C. Owen and D. DeRosier
targeted to the myelin membrane in transgenic
345 In vitro models of tail contraction and mice.
cytoplasmic streaming in amoeboid cells.
P. A. Wight, C. S. Duchala, C. Readhead,
L. W. Janson and D. L. Taylor and W. B. Macklin
IV
455 Differential expression of mRNAs for 477 Induction of a secondary body axis in Xenopus
neurotrophins and their receptors after by antibodies to /3-catenin.
axotomy of the sciatic nerve.
P. D. McCrea, W. M. Brieher, and B. M. Gumbiner
H. Funakoshi, J. Frisen, G. Barbany, T. Tinunusk,
485 Molecular cloning of integrin-associated
O. Zachrisson, V. M. K. Verge, and H. Persson
protein: An inununoglobulin famfly member
467 Human carcinoembryonic antigen, an with multiple membrane-spanning domains
intercellular adhesion molecule, blocks fusion implicated in Ov/Sa-dependent ligand binding.
and differentiation of rat myoblasts.
F. P. Lindberg, H. D. Gresham, E. Schwarz,
F. J. Eidelman, A. Fuks, L. DeMarte, M. Taheri, and E. J. Brown
and C. P. Stanners
Volume 123, Number 3, November 1993
501 Membrane-associated lamins in Xenopus egg 595 Caveolin forms a hetero-oligomeric protein
extracts: Identification of two vesicle complex that interacts with an apical
populations. GPI-linked protein: Implications for the
D. Lourim and G. Krohne biogenesis of caveolae.
M. P. Lisanti, Z. Tang, and M. Sargiacomo
513 The cell proliferation-associated antigen of
antibody Ki-67: A very large, ubiquitous 605 Tetrameric assembly of CHIP28 water
nuclear protein with numerous repeated channels in liposomes and cell membranes:
elements, representing a new kind of cell A freeze-fracture study.
cycle-maintaining proteins.
J. -M. Verbavatz, D. Brown, I. Sabolid, G. Valenti,
C. Schliiter, M. Duchrow, C. Wohlenberg, D. A. Ausiello, A. N. Van Hoek, T. Ma,
M. H. G. ^cker, G. Key, H.-D. Flad, and J. Gerdes and A. S. Verkman
523 Dissociation of the dorsal-cactus complex and 619 The major myosin-binding domain of skeletal
phosphorylation of the dorssd protein correlate muscle MyBP-C (C protein) resides in the
with the nuclear localization of dorsal. COOH-terminal, immunoglobulin C2 motif.
A. M. Whalen and R. Steward T. Okagaki, F. E. Weber, D. A. Fischman,
K. T. Vaughan, T. Mikawa, and F. C. Reinach
535 Cloning and characterization of PASS: A gene
627 PDGF stimulation induces phosphorylation of
required for peroxisome biogenesis in the
talin and cytoskeletal reorganization in skeletal
methylotrophic yeast Pichia pastoris.
muscle.
A. P. Spong and S. Subramani
J. G. Tidball and M. J. Spencer
549 The v-sis protein retains biological activity as a 637 Non-sarcomeric mode of myosin II
l^pe II membrane protein when anchored by organization in the fibroblast lamellum.
various signal-anchor domains, including the
A. B. Verkhovsky, and G. G. Borisy
hydrophobic domain of the bovine papilloma
virus E5 oncoprotein. 653 Regulated tyrosine phosphorylation at the tips
of growth cone filopodia.
Y.-F. Xu, A. N. Meyer, M. K. Webster, B. A. Lee,
and D. J. Donoghue D.-Y. Wu and D. J. Goldberg
665 The kinesin-like protein KLP61F is essential
561 Biochemical dissection of AP-1 recruitment
for mitosis in Drosophila.
onto Golgi membranes.
M. M. S. Heck, A. Pfcreira, P. Pesavento, Y. Yannoni,
L. M. Traub, J. A. Ostrom, and S. Komfeld
A. C. Spradling, and L. S. B. Goldstein
575 The synaptic vesicle proteins SV2, 681 Roles of kinesin and kinesin-like proteins in
synaptotagmin and synaptophysin are sorted to sea urchin embryonic cell division: Evaluation
separate cellular compartments in CHO using antibody microinjection.
fibroblasts.
B. D. Wright, M. Terasaki, and J. M. Scholey
M. B. Feany, A. G. Yee, M. L. Delvy,
and K. M. Buckley 691 Functional analysis of desmoplakin domains:
Specification of the interaction with keratin
585 E>egranulation of individual mast cells in versus vimentin intermediate filament
response to Ca^^ and guanine nucleotides: networks.
An all-or-none event.
T. S. Stappenbeck, E. A. Bomslaeger,
I. Hide, J. P. Bennett, A. Pizzey, G. Boonen, C. M. Corcoran, H. H. Luu, M. L. A. Virata,
D. Bar-Sagi, B. D. Gomperts, and P. E. R. Tatham and K. J. Green
707 Differential regulation of multiple gap junction 741 Mechanical strain induces growth of vascular
transcripts and proteins during rat liver smooth muscle cells via autocrine action of
regeneration. PDGF.
B. T. Kren, N. M. Kumar, S.-q. Wang, N. B. Gilula, E. Wilson, Q. Mai, K. Sudhir, R. H. Weiss,
and C. J. Steer and H. E. Ives
749 TGF-/3i stimulation of cell locomotion utilizes
the hyaluronan receptor RHAMM and
719 Clustering of the acetylcholine receptor by the
hyaluronan.
43-kD protein: Involvement of the zinc finger
domain. S. K. Samuel, R. A. R. Hurta, M. A. Spearman,
J. A. Wright, E. A. Hirley, and A. H. Greenberg
P. B. Scotland, M. Colledge, I. Melnikova, Z. Dai,
and S. C. Froehner 759 A heparin-binding activity on Leishmania
amastigotes which mediates adhesion to
cellular proteoglycans.
729 Clustering and immobilization of acetylcholine
receptors 1^ the 43-kD protein: A possible role D. C. Love, J. D. Esko, and D. M. Mosser
for dystrophin-related protein. 767 ADDITIONS AND CORRECTIONS
W. D. Phillips, P. G. Noakes, S. L. Roberds,
K. P. Campbell, and J. P. Merlie 769 ADDITIONS AND CORRECTIONS
Volume 123, Number 4, November 1993
771 Isolation of the yeast nuclear pore complex. 869 Deflagellation of Chlamydomonas reinhardtti
M. P. Rout and G. Blobel follows a rapid transitory accumulation of
inositol 1,4,5-trisphosphate and requires Ca^^
785 Reconstitution of nuclear protein transport entry.
with semi-intact yeast cells.
Y. G. Yueh and R. C. Crain
G. Schlenstedt, E. Hurt, V. Doye, and P. A. Silver
877 Transgenic mouse models that explore the
799 GTP hydrolysis by complexes of the signal multistep hypothesis of intestinal neoplasia.
recognition particle and the signal recognition
S. H. Kim, K. A. Roth, A. R. Moser,
particle receptor.
and J. I. Gordon
T. Connolly and R. Gilmore
895 Salmonella typhimurium attachment to human
809 The cytoplasmic droplet of rat epididymal intestinal epithelial monolayers: Transcellular
spermatozoa contains saccular elements with signalling to subepithelial neutrophils.
Golgi characteristics.
B. A. McCormick, S. P. Colgan, C. Delp-Archer,
R. Oko, L. Hermo, P. T. K. Chan, A. Fazel, S. I. Miller, and J. L. Madara
and J. J. M. Bergeron
909 Commitment to differentiation and expression
823 Type 2X-myosin heavy chain is coded by a of early differentiation markers in murine
muscle fiber type-specific and developmentally keratinocytes in vitro are regulated
regulated gene. independently of extracellular calcium
C. DeNardi, S. Ausoni, P. Moretti, L. Gorza, concentrations.
M. Velleca, M. Buckingham, and S. Schiafhno V. Drozdoff and W. J. Pledger
837 Orientation and three-dimensional organization 921 Human osteogenic protein-1 induces both
of actin filaments in dividing cultured cells. chondroblastic and osteoblastic differentiation
D. J. Fishkind and Y.-L. Wang of osteoprogenitor cells derived from newborn
rat calvaria.
849 Cytoplasmic dynein plays a role in mammalian
I. Asahina, T. K. Sampath, I. Nishimura,
mitotic spindle formation.
and P. V. Hauschka
E. A. Vaisberg, M. P. Koonce, and J. R. McIntosh
935 Accumulation of actin in subsets of pioneer
859 At least two kinases phosphorylate the MPM-2 growth cone filopodia in response to neural
epitope during Xenopus oocyte maturation. and epithelial guidance cues in situ.
J. Kuang and C. L. Ashom T. P. O’Connor and D. Bentley
vi
949 Identification and differential subcellular 1007 ICAM-3 interacts with LFA-1 and regulates the
localization of the neuronal class C and class LFA-l/ICAM-1 cell adhesion pathway.
D L-type calcium channel al subunits.
M. R. Campanero, M. A. del Pozo, A. G. Arroyo,
J. W. Hell, R. E. Westenbroek, C. Warner, P. Sdnchez-Mateos, T. Hernandez, A. Craig,
M. K. Ahlijanian, W. Prystay, M. M. Gilbert, R. Pulido, and F. Sdnchez-Madrid
T. P. Snutch, and W. A. Catterall
1017 Regulation of a6/31 integrin laminin receptor
963 R2D5 antigen: A calcium-binding function by the cytoplasmic domain of the a6
phosphoprotein predominantly expressed in subunit.
olfactory receptor neurons.
L. M. Shaw and A. M. Mercurio
Y. Nemoto, J. Ikeda, K. Katoh, H. Koshimoto,
Y. Yoshihara, and K. Mori 1027 Tenascin is a cytoadhesive extracellular matrix
component of the human hematopoietic
977 Integrin-cytoskeletal interactions in migrating microenvironment.
fibroblasts are dynamic, asymmetric, and
G. Klein, S. Beck, and C. A. Muller
regulated.
C. E. Schmidt, A. F. Horwitz, D. A. Lauffenburger, 1037 Downregulation of tenascin expression by
and M. P. Sheetz glucocorticoids in bone marrow stromal cells
and in fibroblasts.
993 Identification of sequences required for the
M. Ekblom, R. Fassler, B. Tomasini-Johansson,
efficient localization of the focal adhesion
K. Nilsson, and P. Ekblom
kinase, ppllS'"^’^, to cellular focal adhesions.
J. D. Hildebrand, M. D. Schaller, and J. T. Parsons 1047 ADDITIONS AND CORRECTIONS
Volume 123, Number 5, December 1993
Mini-review 1133 Novel peroxisome clustering mutants and
1049 Submembranous junctional plaque proteins peroxisome biogenesis mutants of
include potential tumor suppressor molecules. Saccharomyces cerevisiae.
S. Tsukita, M. Itoh, A. Nagafuchi, S. Yonemura, J. W. Zhang, Y. Han, and P. B. Lazarow
and S. Tsukita
1149 Mutational and secondary structural analysis of
Regular Articles the basolateral sorting signal of the polymeric
1055 Nuclear organization of splicing snRNPs during immunoglobulin receptor.
differentiation of murine erythroleukemia cells B. Aroeti, P. A. Kosen, I. D. Kuntz, F. E. Cohen,
in vitro. and K. E. Mostov
M. Antoniou, M. Carmo-Fonseca, J. Ferreira, 1161 Triad formation: Organization and function of
and A. I. Lamond the sarcoplasmic reticulum calcium release
1069 The structure of replicating kinetoplast channel and triadin in normal and dysgenic
DNA networks. muscle in vitro.
D. P6rez-Morga and P. T. Englund B. E. Flucher, S. B. Andrews, S. Fleischer,
A. R. Marks, A. Caswell, and J. A. Powell
1081 Multiple regions of NSRl are sufficient for
1175 A spacer protein in the Socc/iaromyces
accumulation of a fusion protein within
cerevisiae spindle pole body whose transcript is
the nucleolus.
cell cycle-regulated.
C. Yan and T. M61^se
J. V. Kilmartin, S. L. Dyos, D. Kershaw,
1093 Targeting and mistargeting of plasma and J. T. Finch
membrane adaptors in vitro.
1185 Yeast actin with a mutation in the
M. N. J. Seaman, C. L. Ball, and M. S. Robinson
“hydrophobic plug” between subdomains 3 and
1107 Mis-assembly of clathrin lattices on endosomes 4 ^266D) dispays a cold-sensitive polymerization
reveals a re^atory switch for coated defect.
pit formation. X. Chen, R. K. Cook, and P. A. Rubenstein
L.-H. Wang, K. G. Rothberg, and R. G. W. Anderson
1197 Peripherin expression in hippocampal neurons
1119 The subcellular distribution of early endosomes induced by muscle soluble factorfs).
is affected by the annexin IIPII complex.
2 2 K. Djabali, A. Zissopoulou, M. J. de Hoop,
T. Harder and V. Gerke S. D. Georgatos, and C. G. Dotti
1207 Temporal analysis of events associated with 1255 Cell and heparin binding in the distall long arm
programmed cell death (apoptosis) of of laminin: Identification of active and cryptic
sympathetic neurons deprived of nerve sites with recombinant and hybrid glycoprotein.
growth factor. U. Sung, J. J. O’Rear, and P. D. Yurchenco
T. L. Deckwerth and E. M. Johnson, Jr.
1223 Axonal regulation of schwann cell integrin 1269 Structure and expression of fibulin-2, a novel
expression suggests a role for a6/34 extracellular matrix protein with multiple
in myelination. EGF-like repeats and consensus motifs for
S. Einheber, T. A. Milner, F. Giancotti, calcium binding.
and J. L. Salzer T.-C. Pan, T. Sasaki, R.-Z. Zhang, R. Fassler,
R. Timpl, and M.-L. Chu
1237 ATP-dependent degradatiojn of a mutant
serine:pyruvate/alanine:glyoxylate
aminotransferase in a primary hyperoxaluria 1279 Thrombin adhesive properties: induction by
type 1 case. plasmin and heparan sulfate.
K. Nishiyama, T. Funai, S. Yokota, and A. Ichiyama R. Bar-Shavit, Y. Eskohjido, J. W. Fenton II,
J. D. Esko, and I. Vlodavsky
1249 The mechanism for the activation of latent
TGF-/3 during co-culture of endothelial cells
and smooth muscle cells: Cell-type specific 1289 Sequence and tissue distribution of the integrin
targeting of latent TGF-jS to smooth a9 subunit, a novel partner of /31 that is widely
muscle cells. distributed in epithelia and muscle.
Y. Sato, F. Okada, M. Abe, T. Seguchi, M. Kuwano, E. L. Palmer, C. Riiegg, R. Ferrando, R. Pytela,
S. Sato, A. Furuya, N. Hanai, and T. Tamaoki and D. Sheppard
Volume 123, Number 6, Part 1, December 1993
Mini-review 1355 A sec63p-BiP complex from yeast is required
1305 The erythropoietin receptor: Its role in for protein translocation in a reconstituted
hematopoiesis and myeloproliferative diseases. proteoliposome.
J. L. Brodsky and R. Schekman
G. D. Longmore, S. S. Watowich, D. J. Hilton,
and H. F. Lodish 1365 Hydrolysis of bound GTP by ARF protein
Regular Articles triggers uncoating of Golgi-derived
COP-coated vesicles.
1309 Eukaryotic initiation factor 5A is a cellular
target of the human immunodeficiency virus G. Tanigawa, L. Ore, M. Amherdt, M. Ravazzola,
type 1 Rev activation domain mediating J. B. Helms, and J. E. Rothman
trans-activation. 1373 Cytoplasmic dynetn-dependent vesicular
M. Ruhl, M. Hinunelspach, G. M. Bahr, transport from early to late endosomes.
F. Hammerschmid, H. Jaksche, B. Wolff, H. Aschauer,
F. Aniento, N. Emans, G. Griffiths, and J. Gruenberg
G. K. Farrington, H. Probst, D. Bevec, and J. Hauber
1389 /3-very low density lipoprotein is sequestered in
1321 Determination of initiation of DNA replication
surface-coimected tubules in mouse peritoneal
before and after nuclear formation in Xenopus
macrophages.
egg cell free extracts.
J. N. Myers, I. Tabas, N. L. Jones, and F. R. Maxheld
Y. Kubota and H. Takisawa
1403 Retrograde lipid traffic in yeast: Identification
1333 Intranuclear filaments containing a nuclear pore of two distinct pathways for internalization of
complex protein. fluorescent-labeled phosphatidylcholine from the
V. C. Cordes, S. Reidenbach, A. Kohler, N. Stuumian, plasma membrane.
R. van Driel, and W. W. Franke L. S. Kean, R. S. Fuller, and J. W. Nichols
1345 NuplSO, a novel nuclear pore complex protein 1421 Mechanisms of urinary K^and excretion:
loc^izing to the cytoplasmic ring and Primary structure and functional expression of
associated fibrils. a novel, H,K-ATPase.
N. Wilken, U. Kossner, J.-L. Sen6cal, U. Scheer, F. Jaisser, J.-D. Horisberger, K. Geering,
and M.-C. Dabauvalle and B. C. Rossier
1431 Egg cortical granule N-acetylglucosaminidase 1545 Targeted expression of a conditional oncogene
is required for the mouse zona block in hematopoietic cells of transgenic mice.
to polyspermy.
K. Ravid, Y. C. Li, H. B. Rayburn,
D. J. Miller, X. Gong, G. Decker, and B. D. Shur and R. D. Rosenberg
1441 Olfactory receptors are displayed on dog mature 1555 Ectopic trkA expression mediates a NGF
sperm cells. survival response in NGF-independent sensory
neurons but not in parasympathetic neurons.
P. Vanderhaeghen, S. Schurmans, G. Vassart,
and M. Parmentier T. E. Allsopp, M. Robinson, S. >\yatt,
and A. M. Davies
1453 Non-chemotactic Dictyostelium discoideum
mutants with altered cGMP signal transduction. 1567 IGF-I is a mitogen involved in
differentiation-related gene expression in
H. Kuwayama, S. Ishida, and P. J. M. Van Haastert
fetal rat brown adipocytes.
1463 440-kD ankyruiB: Structure of the major
M. Lorenzo, A. M. Valverde, T. Teruel, and M. Benito
developmentally regulated domain and selective
localization in unmyelinated axons. 1S77 Multiple levels of control of the stage- and
region-specific expression of rat
W. Chan, E. Kordeli, and V. Bennett
intestin^ lactase.
1475 Interpolar spindle microtubules in PTK cells.
1. Duluc, B. Jost, and J.-N. Freund
D. N. Mastronarde, K. L. McDonald, R. Ding,
1587 Differential effects of over-expressed neural cell
and J. R. McIntosh
adhesion molecule isoforms on myoblast fusion.
1491 Regulated docking of nuclear membrane
D. Peck and F. S. Walsh
vesicles to vimentin filaments during mitosis.
C. Maison, H. Horstmann, and S. D. Georgatos 1597 ^2 integrin engagement triggers actin
polymerization and phosphatidylinositol
1507 The 47-kD lens-specific protein phakinin is a trisphosphate formation in non-adherent
tailless intermediate filament protein and an human neutrophils.
assembly partner of filensin.
R. Lofgren, J. Ng-Sikorski, A. Sjolander,
A. Merdes, F. Gounari, and S. D. Georgatos and T. Andersson
1517 The rod domain of NF-L determines 1607 Targeted deletion of 01 integrins in F9
neurofilament architecture, whereas the end embryonal carcinoma cells affects morphological
domains specify filament assembly and differentiation but not tissue-specific gene
network formation. expression.
S. Heins, P. C. Wong, S. Muller, K. Goldie, L. E. Stephens, J. E. Sonne, M. L. Fitzgerald,
D. W. Cleveland, and U. Aebi and C. H. Damsky
1535 Neural regulation of muscle acetylcholine 1621 ADDITIONS AND CORRECTIONS
receptor e- and a-subunit gene promoters in
1623 ADDITIONS AND CORRECTIONS
transgenic mice.
K. Gundersen, J. R. Sanes, and J. P. Merlie 1625 ADDITIONS AND CORRECTIONS
Volume 123, Number 6, Part 2, December 1993
Mini-review 1649 Inhibition of nuclear protein import by
1631 Breaking through the tight junction barrier. nonhydrolyzable analogues of GTP and
identification of the small GTPase Ran/TC4 as
B. Gumbiner
an essential transport factor.
Regular Articles F. Melchior, B. Paschal, J. Evans, and L. Gerace
1635 SMCl: An essential yeast gene encoding a 1661 The role of CaaX-dependent modifications in
putative head-rod-taU protein is required for membrane association of Xenopus nuclear lamin
nuclear division and defines a new ubiquitous B3 during meiosis and the fate of B3 in
protein family. transfected mitotic cells.
A. V. Strunnikov, V. L. Larionov, and D. Koshland 1. Firmbach-Kraft and R. Stick
1671 Lamin B distribution and association with 1789 Activation of actin polymerization by
peripheral chromatin revealed by optical phosphatidic acid derived from
sectioning and electron microscopy tomography. phosphatidylcholine in IIC9 fibroblasts.
A. S. Belmont, Y. Zhai, and A. Thilenius K. -S. Ha and J. H. Exton
1687 Glut2 surface expression and intracellular 1797 Cell shape and interaction defects in a-spectrin
transport via the constitutive pathway in mutants of Drosophila melanogaster.
pancreatic cells and insulinoma: Evidence for
J. K. Lee, R. S. Coyne, R. R. Dubreuil,
a block in trans-Golgi network exit by L. S. B. Goldstein, and D. Branton
brefeldin A.
1811 Microtubule-dependent control of cell shape and
B. Thorens, N. Gerard, and N. Ddriaz
pseudopodial activity is inhibited by the
1695 Intracellular routing of GLcNAc-bearing antibody to kinesin motor domain.
molecules in thyrocytes: Selective recycling
V. I. Rodionov, F. K. Gyoeva, E. Tanaka,
through the Golgi apparatus. A. D. Bershadsky, J. M. Vasiliev, and V. I. Gelfand
R. Miquelis, J. Courageot, A. Jacq, O. Blanck, 1821 The SLT2 (MPKl) MAP kinase homolog
C. Perrin, and P. Bastiani
is involved in polarized cell growth in
1707 Clathrin facilitates the internalization of seven Saccharomyces cerevisiae.
transmembrane segment receptors for mating
C. Mazzoni, P. Zarzov, A. Rambouig, and C. Mann
pheromones in yeast.
1835 Nerve growth factor regulates the abundance
P. K. Tkn, N. G. Davis, G. F. Sprague,
and distribution of channels in PC12 cells.
and G. S. Payne
N. Sharma, G. DArcangelo, A. Kleinklaus,
1717 In vitro insertion of the 22-kD peroxisomal
S. Halegoua, and J. S. Trimmer
membrane protein into isolated rat liver
peroxisomes. 1845 Interactions of synapsin I with phospholipids:
Possible role in synaptic vesicle clustering and
P. Diestelkotter and W. W. Just
in the maintenance of bilayer structures.
1727 ^COP, a subunit of coatomer, is required for
F. Benfenati, F. Valtorta, M. C. Rossi, F. Onofri,
COP-coated vesicle assembly. T. Sihra, and P. Greengard
O. Kuge, S. Hara-Kuge, L. Orci, M. Ravazzola, 1857 Expression of Wnt-1 in PC12 cells results in
M. Amherdt, G. Tanigawa, F. T. Wieland,
modulation of plakoglobin and E-cadherin
and J. E. Rothman
and increased cellular adhesion.
1735 Two pathways for the degradation of the H2
R. S. Bradley, P. Cowin, and A. M. C. Brown
subunit of the asialoglycoprotein receptor in the
endoplasmic reticulum. 1867 Regulation and activity-dependence of
N-cadherin, NCAM isoforms, and polysialic
M. H. Yuk and H. F. Lodish
acid on chick myotubes during development.
1751 Role of the transmembrane and B. Fredette, U. Rutishauser, and L. Landmesser
extracytoplasmic domain of /3 subunits in
1889 Interferon-a induces the expression of the
subunit assembly, intracellular transport, and
L-selectin homing receptor in human B
functional expression of Na,K-pumps.
lymphoid cells.
P. Jaunin, F. Jaisser, A. T. Beggah, K. Takeyasu,
P. Mangeat, B. C. Rossier, J.-D. Horisberger, S. S. Evans, R. P. Collea, M. M. Appenheimer,
and K. Geering and S. O. Gollnick
1899 The dynamic structure of the pericellular
1761 WIFB cells: An in vitro model for studies of
matrix on living cells.
hepatocyte polarity.
G. M. Lee, B. Johnstone, K. Jacobson,
G. Ihrke, E. B. Neufeld, T. Meads, M. R. Shanks,
and B. Caterson
D. Cassio, M. Laurent, T. A. Schroer, R. E. Pagano,
and A. L. Hubbard 1909 ADDITIONS AND CORRECTIONS
1777 Occludin: A novel integral membrane protein 1911 AUTHOR INDEX FOR VOLUMES 120-123
localizing at tight junctions.
1939 SUBJECT INDEX FOR VOLUMES 120-123
M. Furuse, T. Hirase, M. Itoh, A. Nagafuchi,
S. Yonemura, Sa. Tsukita, and Sh. Tsukita 1959 ACKNOWLEDGMENT