Table Of Content

JOURNAL OF APPLIED TOXICOLOGY J. Appl. Toxicol. 2006; 26: 541-542 Author index to Volume 26 Abdel-Wahhab, M. A., 198, 229 Corlett, J. L., 88, 402 Hinson, J Adani, R., 81 Cromey, D. W., 356 Hoesel, L. N Ahmed, H. H., 198, 229 Crouch, D. J., 88 ~_— iy Akpan, V., 480 Csik. M.. 16. 500 Holland. N. T.. 458 Aksoy, H., 10 Hronek, M., 258 Al-Sultan, M. A. H., 262 Dachir, S., 81 Huang, S., 480 Al-Zoughool, M., 524 Dam, A., 16, 500 Huynh, L., 410 Alderton, M. R., 247 Darbre, P. D., 191 Aldonza, M., 253 Das, S. K., 126, 427 Imai, Y., Aluoch, A. O., 132 Dawson, R. M., 247 Inaba, T., 35 Amitai, G., 81 Degawa, M., 381 Irwin, R. Anshoo, G., 115 Demiralay, R., 301 Arafat, K., 64 Demirci, E., 301 Jederberg, W. W., 402 Arranz, N., 466, 493 Devrim, E., 42 Jenden, D. J., 410 Ave, A., 42 Diodovich, C., 317 Jenkins, R. O., 148 Dolara, P., 480 Jowsey, I. R., 341 Baggs, R. B., Drahos, A., 16, 500 Jun, D., 258, 439 Bajgar, J., ao Dubovicky, M., 368 Ballantyne, B., 387 Dumon, H., 475 Kai, J. W., 25 Bartosova, L., 439 Dundjerski, J., 187 Kassa, J., 64, 262, 309 Basketter, D. A., 341 Durak, I., 42 Kaur, J., 397 Benton, B. J., 452 Duramad, P., 458 Kendall, R. J., 139 Bermejo, A. M., 253 Kennedy, G., 419 Berridge, B. R., 169 Elakovic¢, I., 187 Khan, M., 444 Berthelot, A., 47 Erdogan, G., 301 Kido, T., 351 Bhat, K. R., 452 Eskenazi, B., 458 Kilicoglu, B., 42 Bhatt, P., 239 Eybl, V., 207 Kimber, I., 5, 341 Billam, M., 139 Kiser, R. C., 239 BlanuSa, M., 536 Felipo, R., 475 Kitagawa, A., 178 Bleavins, M. R., 333 Fernandez, P., 253 Knight, S. A., 333 Bludovska, M., 207 Fishbein, E., 81 Kobayashi, E., 351 Bobillier-Chaumont, S., 47 FlaSkarova, E., 368 Kojima, M., 381 Botta, A., 475 Flora, S. J. S., 213 Kopjar, N., 56 Bouzas, A., 253 Fusek, J., 439 Kostial, K., 536 Bowers, R. K., 169 Kotyzova, D., 207 Brézik, M., 500 Gandolfi, A. J., 356 Koutensky, J., 207 Briggs, G. B., 402 Garaj-Vrhovac, V., 56 Kovacikova, Z., 16, 5 Brkljacic, J., 187 Garans, M., 475 Krewski, D., 419 Brozik, M., 16 Garcia, A., 466, 493 Kuéa, K., 64, 262 Gerecke, D. R., 239 Kuca, K., 258, 439 ‘ampi, V., 317 Gillhouse, K., 333 Kulkarni, A. S., 115 ‘andir, O., 42 Goldfarb, P. S., 484 Kunesova, G., 309 ‘arballo, M. A., 293 Goncharov, N. V., 148 Kunkel, R. G., 126 ‘arfi’, M., 317 Gordon, M. K., 239 Kutala, V. K., 444 ‘arolus, B., 356 Green, A. R., 99 ~arter, D. E., 356 Gribaldo, L. 3- ] aGattuta, M. S., 333 ‘asbohm, S. L Gupta, R.,2 1 -3 aish, L., 81 Casillas, R. P., 239 Giirsan, N., 301 arramendy, M. L., 293 Chang, Y.-C., 239 azarus, M., 536 Chantara, W., 517 Hagazi, M. M., 229 LeSeticky, L., 207 Charpin-Kadouch, C., 475 Halstead, B. W., _ Leikauf, J., 458 Charpin, D., 475 Hartley, P. - 24 Lema, M., 253 Chattopadhyay, G., 99 Harvey, P. W., 385 Lestari, F., 99 Celik, M., 10 Hayes, A. Ay9 9 Lodovici, M., 480 Cetin, R., 42 aagpe A. 1., 466, 493 Chialvo, D. R., 410 He, Q., 509 Mach, M., 368 Chinoy, N. J., 533 Macquarrie, L., 98 Copyright © 2006 John Wiley & Sons, Lid AUTHOR INDEX Mahmood, A., 397 Paddle, B. M., 162 Still, K. R., 402 Malerba, I., 317 Pak, Y., | Stollberg-Zagar, K., 1 Malhotra, R. C., 115 Pant, S. C., 115 Sun, W., 410 ManitaSevic, S., 187 Papp, A., 374 Suwazono, Y., 351 Mannaa, F., 198 Park, M. H., 198 Suzuki, H., 509 Markovic, B., 99 Pathak, U., 115 Szabo, A., 374 Mati¢, G., 187 Pauluhn, J., 269, 279 Matsura, T., 178 Pecze, L., 374 Tabernero, M. J., 253 Maupoil, V., 47 Pellizzer, C., 317 lager, I. B., 458 Maurel, G., 475 Peraza, M. A., 356 lakeyoshi, M., 5 Maurici, D., 317 Pershing, L. K., 88, 402 Talaska, G., 524 Mayersohn, M., | Petroianu, G. A., 64, 262 Tang, L., 139 McClintock, S. D., 126 Philippe, S., 419 Tang, M., 139 McKean, C., 139 Piccotti, J. R., 333 ratrai, E., 16, 500 Melchioretto, P., 317 Plant, K. E., 484 Theodorakis, C. W., 139 Meshulam, H., 81 Prakash, A. O., 115 Thiantanawat, A., 517 Minetti, A., 35 Prayag, A., 444 Thomas, C. E., 169 Mohan, I. K., 444 Till, G. O., 126 Mohr, U., 279 Queralt, J., 475 lulinska, J., 500 Moller, L., 466, 493 Monteith, D. K., 169 Radic, B., 56 Uetani, M., 351 Morales, P., 466, 493 Radilov, A. S., 148 Ujhazy, E., 368 Moreno, M. G., 326 Rafter, J., 466, 493 Ulleras, E., 484 Morgan, R. E., 169 Ramadour, M., 475 Unal, F., 10 Muckova, M., 368 Ramesh, A., 427 Urani, C., 317 Mudry, M. D., 293 Ray, R., 452 Mukherjee, S., 427 Raza, S. K., 11 5 Varnai, V. M., 536 Muller, B. D., 162 Reale, C. A., 3 5 Verma, R. J., 5: Muriel, P., 326 Reilly, C. A., 88 Vezér, T., 374 Riley, D. J., 239 Vijayaraghavan, R., 115 Nagelkerke, N., 262 Roch, M., 410 Vrdoljak, A. L., 56 Naidu, M. U. R., 444 Rudge, T. | Nakagawa, H., 351 Wang, J.-S., 139 Nambiar, D., 533 Sabourin, C. | Ward, P. A., 126 Neff, T., 126 Sadlonova, I., 368 Watcharasit, P., 517 Nelson, J. L., 402 Salehi, F., 419 Weiss, B., 25 Nishijo, M., 351 Satayavivad, J., 517 Wells, D., 247 Noda, S., 5 Satish, H. T., 115 Westmoreland, C., 341 Nogawa, K., 351 Saunders, C. R., 427 Whalen, M. M., 132 Normandin, L., 419 Scremin, O. U., 410 Wong, V. K., 162 Norris, J. C., 387 Shem, S$. '&.,. 225 Nurulain, S. M., 262 Shakarjian, M. P., 239 Yamada, K., 178 Sharma, R. P., 509 Yamasaki, K., 5 Ohman-Strickland, P., 239 Shih, T.-M., 410 Yilmaz, S., 10 Ohta, Y., 178 Shobha, J. C., 444 Yiizbasioglu, D., 10 Oishi, M., 351 Shockley, D. C., 427 Opletal, L., 258 Singla, A., 397 Zareba, G., 25 Orct, T., 536 Six, E., 16, 500 Zayed, J., 419 Orlandi, M., 317 Smith, M. G., 126 Zilender, V., 56 Oskarsson, A., 484 Snellings, W. M., 387 Zoia, L., 31/ Ozbilim, G., 301 Soloneski Zwickl, C. M., 169 Copyright © 2006 John Wiley & Sons, Ltd. 1. Appl. Toxicol. 2006; 26: 541-542 JOURNAL OF APPLIED TOXICOLOGY J. Appl Toxicol. 2006; 26: 543 545 Keyword index to Volume 26 1.4-butanediol, 72 biocides, 279 ogenetic endpoints, 293 4-aminobiphenyl, 524 biomarker, 169 okines. 458 5’-methylthioadenosine, 509 biotoxin, 139 y-butyrolactone, 72 bladder cancer, 524 yhydroxybutyric acid, 72 blister, 239 blood. 439. 536 acetylcholinesterase, 258 bovine antibodies, 162 nethasone, 187 aconitase, 148 brain, 536 acrylamide, 198 brain acetylcholinesterase ctl acrylonitrile, 517 breast cancer, 19] tion. acute lung injury, brush border enzyme expression lamage, 115 adamantanes, 56 igase I, 452 adrenal, 484 cadmium, 191, 207 \ repall 452 aerosol, 387 capsaicin, DNA repair mechanism, 452 aflatoxin, 139, 229 carbohydrate, 247 dog, 439 aggregation, 258 carbon tetrachloride, DRDE-07 115 aldehydes, 279 carcinogenic PAH, 480 DRDE-07 analogues, 115 algae, 229 carcinogenicity, 72 allergy, 341 Carica papaya, 533 C-SOD. 500 alternative methods, 484 cauda epididymis, 533 EDXA, 16, 500 aluminium, 191 Caulerpa prolifera, 229 ited plus maze, 35 alveolar macrophages, 16, 279, 500 CBA/N, 5 ELISA, 247 aneugen, 293 CCL. 326 nbryo-fetal toxicity, 368 animal model, 1, 402 CEES, 126 otoxin, 458 anthrax, 162 cell death, 356 rocyte migration, 397 anti-ChE, 81 cell proliferation kinetics, 2 ronment, 475 anti-oxidant liposomes, 126 cell size, 25 vironmental oestrogen, 191 antidotes, 115 Centella asiatica, 213 rdosteine, 301 antioxidant, 198, 444 cerebral cortex, 25 ERK Cll On, . antioxidant activities, 47 Chhe mi1 ca | V abiale,I 2 . 536 antioxidant enzyme, 207 chemoprevention, 198 antioxidant enzymes, 427 Chinese cigarettes, 480 antioxidant foods, 42 chlorpyrifos, 458 antioxidant system, 16 CHO cells, 293 126, 326 antiperspirant, 191] cholesterol, 38 | ymbustion products, 99 antiplatelet activity, 258 cholinesterase, 64, 262 ytometry, 169 anxiety, 35 cholinesterases, 439 luoroacetate, 148 aorta, 47 chromosome aberrations (CAs), luoro¢ itrate, 148 apoptosis, 301 cirrhosis 326 rskoimn 484 aqueous extract, 533 cisplatin, 42 ionisin B,, 509 arsenic, 356 cocaine, 253 functional? observational arsenic toxicity, 213 collagen, 326 ttery, 309 aryloxyacetic derivative herbicide, 368 colorimeter, 58 asialofetuin, 247 combination, 374 assay, 402 combinative toxicity, 139 ATP assay, 99 comet assay, 56, 466, 493 atropine, 309 complex mixtures, 269 general environment, 351 autonomic nervous system, 410 compound 1080, 148 notox ic effects, 56 contaminant, 402 ginsenoside, 198 B(a)P, 480 cortical activity, 374 itathione, 207. 509 BALB/c mice, 333 cortical lateralization, 25 GSH, 115. 500 benchmark dose, 351 cumulative toxicity, 279 benchmark dose low, 351 curcumin, 20 eart. 4 benzo(a)pyrene, 427 cutaneous reactions, | heart rate variability, 410 bifunctional compounds, 81 cyclosporine, 444 h matological parameters, 223 bile, 2c5a3n CYP enzyme, 4!8 4 hepatotoxicity, 229, 509 Copyright © 2006 John Wiley & $44. KEYWORD INDEX hepatotoxicity (rat), 178 log-logistic model, 351 organophosphate pesticides, 458 HepG2, 317 lung effects, 279 oxazolone, 333 hexachlorocyclohexane, 484 lungs, 162, 500 oxidative stress, 42, 207, 213, hexylcinnamic aldehyde, 333 427, 444 HI-6, 309 macrophages, 126 oxime, 64, 262 histology, 500 manganese, 374 oximes, 258 histopathology, 115 manganese complex, 207 HMG-CoA reductase, 381 manganese phosphate/sulfate PAH, 480 hormones, 198 mixture, 419 Panax ginseng extract, 198 house mite allergen, 458 MAP kinases, 132 paraoxon, 64, 262 HPLC, 402 MCP-1, 16 particles, 279 human, 88, 402 MCPA, 368 particulates, 269 human kidney cell line, 356 mercury, 187, 374 pepper spray, 88 human liver microsomes, 524 mercury(2+) chloride, 536 peripheral activity, 374 human lung epithelial cells, 162 metabolic poison, 148 peripheral blood, 169 human lung microvascular metabolism, 72 peripheral sensory irritation, 387 endothelial cells, 162 metalloestrogen, 191 personal defense, 88 human lymphocytes, 293 metallothionein, 47 pharmacokinetics, 402 human NK cells, 132 methyl salicylate, 333 phospholipidosis, 169 humans, 458 micronuclei (MN), 10 PRC. 517 MIP-la, 16 PMMA (polymethy! methacrylate), 99 ibuprofen, 81 mitochondria, 356 pneumocytes, 16 immunoglobulins, 500 mitotic index, 293 pneumocytes type II, 500 immunotoxicity mixtures, 458 mitotic spindle disturbances, 293 poly(ADP-ribose) polymerase in silico, 341 mold-mycotoxin, 475 (PARP), 452 in vitro, 341 monofluorides, 148 polycyclic aromatic hydrocarbons, 427 in vitro cytotoxicity, 99 mosquito coil smoke, 269, 279 prenatal exposure, 25, 35 indoor pollution, 475 motor activity, 427 prophylaxis, 115 induction, 47 mouse, 5, 387 protection, 213, 229 inhalation, 387 mRNA expression, 484 protective antigen, 162 inhalation exposure, 419 MTS assay, 99 pulmonary fibrosis, 16 inhalation testing of combustion mycotoxin, 139 pyridostigmine, 81 atmospheres, 269 myeloperoxidase, 178 pyridostigmine bromide, 410 inhalation toxicity testing of complex mixtures, 279 N-acetylcysteine, 301 rabbit, 368 inhalation toxicity, 269 N-glucuronidation, 524 race, 88 inhibitor, 247 N-methyl-D-aspartate (NMDA) rat, 25, 35, 374, 381, 387, 500 iNOS, 326 receptors, 56 rat intestine, 397 interleukin 2, 12, 132 N-nitrosamines, 466, 493 reactivation, 439 intoxication, 439 necrosis, 326 reactivators, 258 irritants, 269 nephrotoxicity, 42, 444 reactive oxygen species isoproterenol, 47 nerve agents, 258, 410 metabolism, 178 isothiocyanates compounds, 466, 493 neuropathology, 419 reduced glutathione, 178 neurotoxicity, 198, 309, 427 refractory ceramic fibres, 500 K027, 309 neutropenia, 178 renal effects, 351 K048, 309 neutrophils, 126 ricin, 247 kidney, 387, 536 nickel toxicity, 397 risk assessment, 402 Nile red, 169 Laurencia obtusa, 229 nitric oxide, 326 S-adenosylmethionine, 509 lead, 223, 374 NO, 326 sarin, 410, 439 lead nitrate, 381 non-radioisotopic, 5 sensitisation, 34] lectins, 16 NRU assay, ATP assay, 99 sensorimotor development, 35 lethal factor, 162 NSAID, 81 sex-difference, 381 lethal synthesis, 148 sister chromatid exchanges, 293 lindane, 484 obidoxime, 309 sister chromatid exchanges lipid peroxidation, 207, 427 occupational exposure, 10 (SCEs), 10 lipopolysaccharide, 301 oestrogen, 191 skin, 88, 239, 341, 402 liver, 387, 536 offset printing workers, 10 skin sensitization, 333 liver injury, 326 oleoresin capsicum, 88 smoking, 191 LLNA, 333 organophosphate, 64, 262 smoking machine yields, 480 local lymph node assay, 5 organophosphates, 258 soman, 56, 81, 439 Copyright © 2006 John Wiley & Sons, Ltd. J. Appl. Toxicol. 2006; 26: 543-545 KEYWORD INDEX sperm motility, 533 rCDD, 25 tyrosine aminotransferase, 187 sphingolipid, 509 temperature, 83 Spirulina, 444 TEWL, 88 urinary $,-microglobulin concentration, steroid, 484 therapy, 148 sterol regulatory element thermal decomposition, urinary cadmium concentration, 351 binding protein-2, 381 thiabendazole, 293 urinary N-acetyl-B-p-glucosaminidase stone-wool, 16 thiomersal, 536 (NAG) activity, 351 styrene-7,8-oxide, 317 threshold level, 351 urinary total protein concentration, 351 styrene, 317 Tinca tinca, 223 suckling rat, 536 topical, 33: vitreous humor, 253 sulfur mustard, 81, 115, toxicity, ‘ VX. 439 superoxide dismutase, 178 toxicology, 402, 475 trace elements, 207 vhole blood culture, 458 T-2 toxin, 139 tremor, 419 tabun, 309 tributyltin, 132 xanthine oxidase, 178 tar levels, 480 triethylene glycol, 387 xenobiotics, 169 TCA, 148 tumor marker, 229 xenoestrogen, 191 Copyright © 2006 John Wiley & Sons, Ltd /, Appl. Toxicol. 2006; 26: 543-545 Journal of Applied Toxicology 2006 Volume 26 JJATDK 26(1-6) 1-545 (2006) ISSN 0260-437X ) WILEY Publishers Since 1807 Chichester - New York - Weinheim - Brisbane - Singapore - Toronto Journal of Applied Toxicology (J Appl Toxicol) AN INTERNATIONAL JOURNAL EDITOR-IN-CHIEF EUROPEAN EDITOR EDITOR, JAPAN ACCEPTING EDITOR, USA Harry Salem Philip W. Harvey Tohru Inoue Saura Sahu Edgewood Chemical & Covance Laboratories UK Ltd, Director, Center for Biological Division of Toxicology) Biological Center Toxicology Safety & Research, Office of Applied Research and AMSRD-ECB-RT, Building Otley Road National Institute of Health Sciences Safety Assessment E3330/143 Harrogate 1-18-] Kamiyoga Center for Food Safety and Aberdeen Proving Ground North Yorkshire Setagavaku {pplied Nutrition MD 21010-5424, USA HG3 IPY, UK Tokvo 158-8501 U.S. Food and Drug Administration Tel: +1 410 436 3034 Tel: +44 (1423) 848421 Japan 8301 Muirkirk Road, Laurel Fax: +1 410 436 3930 Fax: +44 (1423) 569595 E-mail: tohru(@@nihs.go.jp MD 20708, USA E-mail: [email protected] E-mail: [email protected] E-mail: saura.sahu(@cfsan.fda.gov EMERGING ISSUES REVIEWS EDITOR TOXICOLOGY UPDATES FOUNDING EDITOR EDITOR Kannan Krishnan EDITOR Michael Greenwood James J. McGrath Dep. Santé Environmental/Santé an Alan C. Katz Travail, Université de Montréal ToXcel ASSISTANT EDITOR 6601 Huntingridge Road 2375 Cote Ste. Catherine Chapel Hill, NC 27514, USA Bureau 4105 Toxicology & Regulatory Afjairs Teresa Rudd E-mail: [email protected] Montreal OC H3T 1A8. Canada 7545 Presidential Lane. Manassas VA 20109, USA E-mail: kannan.krishnan(a E-mail: [email protected] umontreal.ca EDITORIAL ADVISORY BOARD J. Ashby D. Lison Syngenta Central Toxicology Laboratory, Macclesfield, Cheshire, UK Catholic University of Louvain, Belgium P. Baldrick E. A. Lock Covance Laboratories Ltd., Harrogate, UK Schoel of Biomolecular Sciences, Liverpool John Moores University, UK B. Ballantyne H. Maibach Union Carbide Corporation, Danbury, CT, USA Universityo f California Medical School, San Francisco, CA, USA S. I. Baskin M. McFarlane US Army Medical Research Institute of Chemical Defense, MD, USA GlaxoSmithKline, Ware, UK J. R. Beall N. A. Monteiro-Riviere US Department of Energy, Washington, DC, USA North Carolina State University, Raleigh, NC, USA D. Benford R. A. Parent Food Standards Agency, London, UK Consultox Ltd, Damariscotta, ME, USA J. F. Borzelleca J. Pauluhn Medical College of Virginia, Richmond, VA, USA Institute of Toxicology, Bayer HealthCare AG, Wuppertal, Germany W. J. Brock G. A. Petroianu Unilever Research-US, Edgewater, NJ, USA Faculty of Medicine and Health Sciences, United Arab Emirates N. Chernoff University, Abu Dhabi, United Arab Emirates US Environmental Protection Agency, NC, USA S. Price S. Chivers School of Biomedical and Molecular Sciences, University of Surrey Syngenta Central Toxicology Laboratory, Macclesfield, UK Guildford, UK J. Descotes G. Reddy Lyon Poison Centre, Lyon, France US Army Center for Health Promotion and Preventive Medicine S. W. Ernst Edgewood, Maryland, USA AstraZeneca R&D, Moélndal, Sweden H. Satoh D. J. Everett Tohoku University Graduate School of Medicine, Sendai, Japan Covance Laboratories Ltd., Harrogate, UK K. Savolainen V. Eybl Finnish Institute of Occupational Health, Helsinki, Finland Charles University Faculty of Medicine, Pilsen, Czech Republic V. M. Seabaugh S. C. Gad Falls Church, VA, USA Gad Consulting Services, Cary, NC, USA D. E. Sharp P. Goldfarb Boehringer-Ingelheim Pharmaceuticals, Inc., Ridgefi« d, CT, USA University of Surrey, Guildford, UK A. G. Smith S. Green MRC Toxicology Unit, University of Leicester, UK Howard University, Washington, DC, USA R. Snyder S. Halbach EOHSI Busch Campus, Piscataway, NJ, USA GSF Research Centre, Neuherberg, Germany H. Soreq G. Healing The Hebrew University of Jerusalem, Israel AstraZeneca, Alderley Park, Macclesfield, UK R. G. Tardiff R. Kapp, Jr The Sapphire Group Inc., Bethesda, MD, USA BioTox, Richmond, VA, USA R. Valentine S. A. Katz E. I. du Pont de Nemours & Co., Newark, DE, USA Rutgers University, Camden, NJ, USA E. K. Weisburger F. Koschier Rockville, MD, USA Pfizer Inc., Morris Plains, NJ, USA C. Winder K. Kostial University of New South Wales, Sydney, Australia Institute for Medical Research & Occupational Health, Zagreb, C. Winek Croatia Duquesne University, Pittsburgh, PA, USA JOURNAL OF APPLIED TOXICOLOGY J. Appl. Toxicol. 2006; 26: iii-vi Contents of Volume 26 NUMBER | JANUARY/FEBRUARY 2006 Research Articles A porcine model for fixed drug eruptions in humans: the case of antipyrine in the Yucatan micropig Y. PAK, K. STOLLBERG-ZAGAR AND M. MAYERSOHN Advantage of using CBA/N strain mice in a non-radioisotopic modification of the local lymph node assay M. TAKEYOSHI, S. NODA, K. YAMASAKI AND I. KIMBER Genotoxicity study in lymphocytes of offset printing workers H. AKSOY, S. YILMAZ, M. CELIK, D. YUZBASIOGLU AND F. UNAI The effect of stone-wool on rat lungs and on the primary culture of rat alveolar macrophages and type II pneumocytes E. TATRAI, M. BROZIK,A .D RAHOS, Z. KOVACIKOVA, E. SIX, M. CSIK AND A. DAM Sex-specific alterations of cerebral cortical cell size in rats exposed prenatally to dioxin R. HOJO, G. ZAREBA, J. W. KAI, R. B. BAGGS AND B. WEISS Sensorimotor developmental delays and lower anxiety in rats prenatally exposed to cadmium A. MINETTI AND C. A. REALE Cisplatin impairs antioxidant system and causes oxidation in rat kidney tissues: possible protective roles of natural antioxidant foods R. CETIN, E. DEVRIM, B. KILICOGLU, A. AVCI, O. CANDIR AND i. DURAK Metallothionein induction in the liver, kidney, heart and aorta of cadmium and isoproterenol treated rats S. BOBILLIER-CHAUMONT, V. MAUPOIL AND A. BERTHELOT Evaluation of antidotal effects of adamantyl derivative Tamorf in soman poisoning A. LUCIC VRDOLJAK, B. RADIC, V. GARAJ-VRHOVAC, N. KOPJAR AND V. ZLENDER Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: in vitro reactivation of red blood cell acetylcholinesterase inhibitied by paraoxon G. A. PETROIANU, K. ARAFAT, K. KUCA AND J. KASSA A review of evidence leading to the prediction that 1,4-butanediol is not a carcinogen R. D. IRWIN Bifunctional compounds eliciting anti-inflammatory and anti-cholinesterase activity as potential treatment of nerve and blister chemical agents poisoning G. AMITAI, R. ADANI, E. FISHBEIN, H. MESHULAM, I. LAISH AND S. DACHIR Assessment of pepper spray product potency in Asian and Caucasian forearm skin using transepidermal water loss, skin temperature and reflectance colorimetry L. K. PERSHINGC,. A. REILLY, J. L. CORLETT AND D. J. CROUCH Book Review Waste treatment and disposal (2nd Edition) L. MACQUARRIE NUMBER 2 MARCH/APRIL 2006 Research Articles Comparative assessment of three in vitro exposure methods for combustion toxicity F. LESTARI, B. MARKOVIC, A. R. GREEN, G. CHATTOPADHYAY AND A. J. HAYES Evaluation of analogues of DRDE-07 as prophylactic agents against the lethality and toxicity of sulfur mustard administered through percutaneous route A. S. KULKR.A VRJANYARIAG,HA VAN, G. ANSHOO, H. T. SATISH, U. PATHAK, S. K. RAZA, S. C. PANT, R. C. MALHOTRA AND A. O. PRAKASH Attenuation of half sulfur mustard gas-induced acute lung injury in rats S. D.M CCLINTOCK, L. M. HOESEL, S. K. DAS,G . O. TILL, T. NEFF, R. G. KUNKEL, M. G. SMITH AND P. A. WARD Effects of interleukins 2 and 12 on TBT-induced alterations of MAP kinases p38 and p44/42 in human natural killer cells A. O. ALUOCH AND M. M. WHALEN Comparative acute and combinative toxicity of aflatoxin B, and T-2 toxin in animals and immortalized human cell lines C. MCKEAN, L. TANG, M. BILLAM, M. TANG, C. W. THEODORAKIS, R. J. KENDALL AND J.-S. WANG CONTENTS OF VOLUME 26 Toxicology of fluoroacetate: a review, with possible directions for therapy research N. V. GONCHAROY, R. O. JENKINS AND A. S. RADILOV The cytotoxic effect of anthrax lethal toxin on human lung cells in vitro and the protective action of bovine antibodies to PA and LF B. M. PADDLE, V. K. WONG AND B. D. MULLER A clinical flow cytometric biomarker strategy: validation of peripheral leukocyte phospholipidosis using Nile red B. W. HALSTEAD, C. M. ZWICKL, R. E. MORGAN, D. K. MONTEITH, C. E. THOMAS, R. K. BOWERS AND B. R. BERRIDGE Preventive effect of neutropenia on carbon tetrachloride-induced hepatotoxicity in rats Y. OHTA, Y. IMAI, T. MATSURA, A. KITAGAWA AND K. YAMADA Mercury influences rat liver tyrosine aminotransferase activity and induction by dexamethasone J. DUNDJERSKI, J. BRKLJACIC, I. ELAKOVIC, S. MANITASEVIC AND G. MATIC NUMBER 3 MAY/JUNE 2006 Review Article Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast P. D. DARBRE Research Articles Protective role of Panax ginseng extract standardized with ginsenoside Rg3 against acrylamide-induced neurotoxicity in rats F. MANNAA, M. A. ABDEL-WAHHAB, H. H. AHMED AND M. H. PARK The influence of curcumin and manganese complex of curcumin on cadmium-induced oxidative damage and trace elements status in tissues of mice V. EYBL, D. KOTYZOVA, L. LESETICKY, M. BLUDOVSKA AND J. KOUTENSKY Effect of Centella asiatica on arsenic induced oxidative stress and metal distribution in rats R. GUPTA AND S. J. S. FLORA Hematological parameters in tench Tinca tinca after short term exposure to lead S. L. SHAH Prevention of aflatoxin B,-initiated hepatotoxicity in rat by marine algae extracts M. A. ABDEL-WAHHAB, H. H. AHMED AND M. M. HAGAZI Preferential expression of matrix metalloproteinase-9 in mouse skin after sulfur mustard exposure M. P. SHAKARJIAN, P. BHATT, M. K. GORDON, Y.-C. CHANG, S. L. CASBOHM, T. L. RUDGE, R. C. KISER, C. L. SABOURIN, R. P. CASILLAS, P. OHMAN-STRICKLAND, D. J. RILEY AND D. R. GERECKI Monovalent and polyvalent carbohydrate inhibitors of ricin binding to a model of the cell-surface receptor R. M. DAWSON, M. R. ALDERTON, D. WELLS AND P. G. HARTLEY GC-FID determination of cocaine and its metabolites in human bile and vitreous humor P. FERNANDEZ, M. ALDONZA, A. BOUZAS, M. LEMA, A. M. BERMEJAOND M. J. TABERNERO Effect of some acetylcholinesterase reactivators on human platelet aggregation in vitro D. JUN, K. KUCA, M. HRONEK AND L. OPLETAL Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: survival in rats exposed to the organophosphate paraoxon G. A. PETROIANU, S. M. NURULAIN, N. NAGELKERKE, M. A. H. AL-SULTAN, K. KUCA AND J. KASSA Mosquito coil smoke inhalation toxicity. Part I: Validation of test approach and acute inhalation toxicity J. PAULUHN Mosquito coil smoke inhalation toxicity. Part Il: Subchronic nose-only inhalation study in rats J. PAULUHN AND U. MOHR NUMBER 4 JULY/AUGUST 2006 Research Articles Genotoxic and aneugenic properties of an imidazole derivative M. A. CARBALLO, A. S. HICK, S. SOLONESKI, M. L. LARRAMENDY AND M. D. MUDRY Comparison of the effects of erdosteine and N-acetylcysteine on apoptosis regulation in endotoxin-induced acute lung injury R. DEMIRALAY, N. GURSAN, G. OZBILIM, G. ERDOGAN AND E. DEMIRCI