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Japanese Journal of Cancer Research: Gann. 1993: Vol 84 Table of Contents PDF

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Preview Japanese Journal of Cancer Research: Gann. 1993: Vol 84 Table of Contents

CONTENTS Vol. 84 1993 1-103 RAPID COMMUNICATIONS Southernmost Carriers of HTLV-I/II in the World L. Cartier, F. Araya, J. L. Castillo, V. Zaninovic, M. Hayami, T. Miura, J. Imai, S. Sonoda, H. Shiraki, K. Miyamoto and K. Tajima Aberrant Expression of the p53 Tumor Suppressor Gene in Adult T-Cell Leukemia and HTLV-I-infected Cells K. Yamato, T. Oka, M. Hiroi, Y. Iwahara, S. Sugito, N. Tsuchida and I. Miyoshi Differential Alterations of Dihydrofolate Reductase Gene in Human Leukemia Cell Lines Made Resistant to Various Folate Analogues H. Miyachi, Y. Takemura, H. Kobayashi, K. Ando and Y. Ando REGULAR PAPERS Relationship of Diet to Small and Large Adenomas of the Sigmoid Colon S. Kono, K. Imanishi, K. Shinchi and F. Yanai Sequential Observation of Rat Prostate Lesion Development Induced by 3,2’-Dimethyl-4-aminobipheny! and Testosterone T. Shirai, K. Imaida, S. Iwasaki, T. Mori, M. Tada and N. Ito Effects of X-Irradiation on N-Methyl-N-nitrosourea-induced Multi-organ Carcinogenesis in Rats Y. Morishita, T. Tanaka, H. Mori and S. Sasaki Effect of an Inhibitor of Tumor Promotion, a-Difluoromethylornithine, on Tumor Induction by Repeated Beta Irradiation in Mice A. Ootsuyama and H. Tanooka bcl-2 Gene Rearrangement Analysis of Japanese Follicular Lymphomas by Polymerase Chain Reaction in Formalin-fixed, Paraffin-embedded Tissue Specimens S. Mitani, N. Aoki, S. Mizutani, M. Fujiwara, T. Kitagawa, T. Uehara and S. Mori Random Process of Metastasis and Generation of Heterogeneity in a Mouse Sarcoma Line O. Niwa, Y. Enoki, S. Sadamoto, K. Kamiya and K. Yokoro Characterization of Mammary Plaques in DDD Mice Congenic for Mtv-2 Gene, DDD/1-Mtv-2/Mtv-2 A. Matsuzawa, T. Kaneko, Y. Takeda, A. Murakami and A. Tsubura Artificial Pneumothorax as a Risk Factor for Development of Pleural Lymphoma K. Aozasa, M. Ohsawa, K. Iuchi, K. Tajima, H. Komatsu and M. Shimoyama T Cell Response to Embryonal Carcinoma F9 Cells: Induction and Characterization of T Cell Receptor aß* Double-negative Cytotoxic T Lymphocytes M. Imada and S. Fujimoto Characterization of OM-B Monoclonal Antibody-defined Antigen Associated with Mucinous Type Human Ovarian Tumor K. Nishida, R. Ueda, K. Sakakibara, Y. Minoura, M. Ohta, Y. Ariyoshi and T. Takahashi A Cancer-reactive Human Monoclonal Antibody Derived from a Colonic Cancer Patient Treated with Local Immunotherapy T. Yagyu, T. Monden, M. Baba, Y. Tamaki, T. Takeda, T. Kobayashi, T. Shimano, Y. Tsuji, H. Matsushita, H. Osawa, H. Murakami and T. Mori The Mechanism of the Difference in Cellular Uptake of Platinum Derivatives in Non-small Cell Lung Cancer Cell Line (PC-14) and Its Cisplatin-resistant Subline (PC-14/CDDP) T. Ohmori, T. Morikage, Y. Sugimoto, Y. Fujiwara, K. Kasahara, K. Nishio, S. Ohta, Y. Sasaki, T. Takahashi and N. Saijo Analysis of DNA Fragmentation in Human Uterine Cervix Carcinoma HeLa S。 Cells Treated with Duocarmycins or Other Antitumor Agents by Pulse Field Gel Electrophoresis A. Okamoto, M. Okabe and K. Gomi JPN. J. CANCER RES. 84, 1993 Antitumor Activity of Oenothein B, a Unique Macrocyclic Ellagitannin K. Miyamoto, M. Nomura, M. Sasakura, E. Matsui, R. Koshiura, T. Murayama, T. Furukawa, T. Hatano, T. Yoshida and T. Okuda 105-213 RAPID COMMUNICATIONS Induction of BCR-ABL Fusion Genes by in vitro X-Irradiation T. Ito, T. Seyama, T. Mizuno, T. Hayashi, K. S. Iwamoto, K. Dohi, N. Nakamura and M. Akiyama Detection of PML/Retinoic Acid Receptor a Gene Rearrangements by Polymerase Chain Reaction Using Genomic DNA in Patients with Acute Promyelocytic Leukemia S. Tashiro, K. Tanaka, H. Asou, T. Kyo, H. Dohy, K. Suzuki and N. Kamada Neutralizing Antibody to Vesicular Stomatitis Virus (HTLV-I) Pseudotype in Infants Born to Seropositive Mothers Y. Iwahara, T. Sawada, H. Taguchi, H. Hoshino, M. Umemoto, H. Take, S. Foung and I. Miyoshi Helicobacter pylori May Be Transmitted through Gastrofiberscope Even after Manual Hyamine Washing M. Katoh, D. Saito, T. Noda, S. Yoshida, Y. Oguro, Y. Yazaki, T. Sugimura and M. Terada REGULAR PAPERS Inhibitory Effects of Inhibitors of Arachidonic Acid Metabolism on the Evolution of Rat Liver Preneoplastic Foci into Nodules and Hepatocellular Carcinomas with or without Phenobarbital Exposure Q. Tang, A. Denda, T. Tsujiuchi, M. Tsutsumi, T. Amanuma, Y. Murata, H. Maruyama and Y. Konishi Inhibitory Effect of Potassium Citrate on Rat Renal Tumors Induced by N-Ethyl-N-hydroxyethylnitrosamine Followed by Potassium Dibasic Phosphate N. Konishi, K. Nishii, I. Hayashi, S. Nakaoka, K. Matsumoto, T. Yabuno, Y. Kitahori and Y. Hiasa Time-dependent Modulation of Liver Lesion Development in Opisthorchis-infected Syrian Hamster by an Antihelminthic Drug, Praziquantel W. Thamavit, M. A. Moore, S. Sirisinha, T. Shirai and N. Ito Influence of Aging on Multi-organ Carcinogenesis in Rats Induced by N-Methyl-N-nitrosourea M. Mizoguchi, H. Naito, Y. Kurata, M.-A. Shibata, H. Tsuda, C. P. Wild, R. Montesano and S. Fukushima Construction of Immunoradiometric Assay for Circulating c-erbB-2 Protooncogene Product in Advanced Breast Cancer Patients M. Hosono, T. Saga, H. Sakahara, H. Kobayashi, M. Shirato, K. Endo, T. Yamamoto, T. Akiyama, K. Toyoshima and J. Konishi Persistently Human Immunodeficiency Virus Type 1-infected T Cell Clone Expressing Only Doubly Spliced mRNA Exhibits Reduced Cell Surface CD4 Expression M. Kishi, Y. Nishino, K. Ohki, T. Kimura and K. Ikuta Infrequent ras Mutation in Human Stomach Cancers M. Koshiba, O. Ogawa, T. Habuchi, S. Hamazaki, T. Shimada, R. Takahashi and T. Sugiyama Alterations of Integrin Expression in Human Lung Cancer S. Suzuki, T. Takahashi, S. Nakamura, K. Koike, Y. Ariyoshi, T. Takahashi and R. Ueda Quantitative Comparison of Initiation and Mutation Phenotypes in Hepatocytes of the Analbuminemic Rat Y. P. Dragan, C. Laufer, A. J. Koleske, N. Drinkwater and H. C. Pitot Reduced Expression of nm23 Is Associated with Metastasis of Human Gzstric Carcinomas H. Nakayama, W. Yasui, H. Yokozaki and E. Tahara Intracellular Metabolism and Cytotoxicity of Transferrin-Neocarzinostatin Conjugates of Differing Molar Ratios K. Sasaki, Y. Kohgo, J. Kato, H. Kondo and Y. Niitsu CONTENTS Comparative Studies on the Metabolism of New Fluorinated Pyrimidine Drugs in the Liver by in vivo ?F Magnetic Resonance Spectroscopic Observation M. Harada, H. Nishitani, K. Koga, I. Miura and A. Kimura Enhanced Antitumor Efficacy of a Combination of CPT-11, a New Derivative of Camptothecin, and Cisplatin against Human Lung Tumor Xenografts S. Kudoh, M. Takada, N. Masuda, K. Nakagawa, K. Itoh, Y. Kusunoki, S. Negoro, K. Matsui, N. Takifuji, H. Morino and M. Fukuoka Delivery of Lymph Node-targeted Adriamycin by Gastric Submucosal Liposomal Injection in Rabbits Y. Akamo, T. Yotsuyanagi, I. Mizuno, T. Ichino, N. Tanimoto, S. Kurahashi, T. Saito, T. Yamamoto, T. Yasui, Y. Itabashi and J. Yura 215-353 RAPID COMMUNICATIONS Differential Expression of a Human Sperm-specific Isozyme in Seminoma Cells Transplanted in Scid-nu™ Mice H. Takatera, T. Nomura and H. Itatani Abnormal Hepatic Iron Accumulation in LEC Rats J. Kato, Y. Kohgo, N. Sugawara, S. Katsuki, N. Shintani, K. Fujikawa, E. Miyazaki, M. Kobune, N. Takeichi and Y. Niitsu REGULAR PAPERS Possible Tumor-initiating and -promoting Activity of p-Methylcatechol and Methylhydroquinone in the Pyloric Mucosa of Rat Stomach C. Furihata, S. Oguchi and T. Matsushima Demonstration of Initiation Potential of Carcinogens by Induction of Preneoplastic Glutathione S-Transferase P-Form-positive Liver Cell Foci: Possible in vivo Assay System for Environmental Carcinogens H. Tsuda, K. Matsumoto, H. Ogino, M. Ito, I. Hirono, M. Nagao, K. Sato, R. Cabral and H. Bartsch Correlation between Medium-term Multi-organ Carcinogenesis Bioassay Data and Long-term Observation Results in Rats A. Hagiwara, H. Tanaka, K. Imaida, S. Tamano, S. Fukushima and N. Ito Genotypic Analysis of Epstein-Barr Virus Associated with Nasopharyngeal Carcinoma of Japanese Patients S. Tamura, M. Kunimoto, T. Tabata and O. Yoshie B-raf Oncogene: Activation by Rearrangements and Assignment to Human Chromosome 7 T. Kamiyama, N. Aoki and Y. Yuasa Molecular Heterogeneity of the PML Gene Rearrangement in Acute Promyelocytic Leukemia: Prevalence and Clinical Significance H. Fukutani, T. Naoe, H. Yoshida, S. Yamamori and R. Ohno Cell-density-dependent Expression of Cypla2 Gene in Monolayer-cultured Adult Mouse Hepatocytes N. Nemoto and J. Sakurai Activation of Cyplal and Cypla2 Genes in Adult Mouse Hepatocytes in Primary Culture N. Nemoto and J. Sakurai Structure of 85 kDa Subunit of Human Phosphatidylinositol 3-Kinase Analyzed by Using Monoclonal Antibodies S. Tanaka, M. Matsuda, S. Nagata, T. Kurata, K. Nagashima, Y. Shizawa and Y. Fukui Establishment and Characterization of a Simian Virus 40-Immortalized Osteoblastic Cell Line from Normal Human Bone H. Chiba, N. Sawada, T. Ono, S. Ishii and M. Mori JPN. J. CANCER RES. 84, 1993 Purification and Characterization of NF-R2 that Regulates the Expression of the Human Multidrug Resistance (MDR1) Gene T. Takatori, M. Ogura and T. Tsuruo Use of Serum Gamma-enolase and Aldolase A in Combination as Markers for Renal Cell Carcinoma M. Takashi, T. Sakata and K. Kato Morphometric Analysis of Colonic Adenomatous Polyps N. Tsuno, T. Muto, Y. Kubota, T. Sawada and H. Nagawa Transforming Growth Factor-8 (TGF-8)-mediated Immunosuppression in the Tumor-bearing State: Enhanced Production of TGF-8 and a Progressive Increase in TGF- Susceptibility of Anti-tumor CD4* T Cell Function X.-F. Li, H. Takiuchi, J.-P. Zou, T. Katagiri, N. Yamamoto, T. Nagata, S. Ono, H. Fujiwara and T. Hamaoka Antimetastatic Effect by Anti-adhesion Therapy with Cell-adhesive Peptide of Fibronectin in Combination with Anticancer Drugs I. Saiki, J. Yoneda, H. Kobayashi, Y. Igarashi, H.K omazawa, Y. Ishizaki, I. Kato and I. Azuma Hyperthermic Enhancement of Cytotoxicity and Increased Uptake of cis-Diamminedichloroplatinum(II) in Cultured Human Esophageal Cancer Cells T. Miyahara, K. Ueda, M. Akaboshi, Y. Shimada, M. Imamura and H. Utsumi Cytokines Induce Uridine Phosphorylase in Mouse Colon 26 Carcinoma Cells and Make the Cells More Susceptible to 5’-Deoxy-5-fluorouridine H. Eda, K. Fujimoto, S. Watanabe, T. Ishikawa, T. Ohiwa, K. Tatsuno, Y. Tanaka and H. Ishitsuka Caffeine Modulates the Antitumor Activity and Toxic Side Effects of Adriamycin Y. Sadzuka, E. Mochizuki and Y. Takino 355-479 RAPID COMMUNICATIONS Establishment of a Human Small Cell Lung Carcinoma Cell Line Carrying Amplification of c-myc Gene and Chromosomal Translocation of t(3p;6p) and t(12q;17p) A. Kato, T. Kamiyama, S. Yamaguchi, K. Sudo, S. Mori, M. Sekiguchi, N. Aoki and M. Shibuya Immunohistochemical Type Distinction of a-Fetoprotein in Various a-Fetoprotein-secreting Tumors T. Okamoto, K. Hirabayashi and T. Ishiguro REGULAR PAPERS Effect of Mass Screening for Breast Cancer from the Aspect of Psychosocial Assessment of the Quality of Life T. Yokoe, T. Ishida, S. Tominaga, T. Kuroishi, T. Morimoto, H. Tashiro, S. Itoh, R. Abe, J. Ota, T. Horino, T. Taguchi, K. Honda, M. Sasakawa, Y. Kashiki, S. Yamamoto, K. Enomoto, M. Ogita, K. Yoshida, C. Kido, M. Fukuda, H. Watanabe and M. Izuo Novel Interleukin-2 Dependent T-Cell Line Derived from Adult T-Cell Leukemia Not Associated with Human T-Cell Leukemia Virus Type I Y. Kagami, K. Tobinai, T. Kinoshita, H. Nagai, T. Hotta, M. Seto, R. Ueda and H. Saito Clonal Analysis of Multiple Point Mutations in the N-ras Gene in Patients with Acute Myeloid Leukemia K. Kubo, T. Naoe, H. Kiyoi, H. Fukutani, Y. Kato, T. Oguri, S. Yamamori, Y. Akatsuka, Y. Kodera and R. Ohno Variation in K-ras Codon 12 Point Mutation Rate with Histological Atypia within Individual Colorectal Tumors K. Soh, A. Yanagisawa, H. Hiratsuka, H. Sugano and Y. Kato CONTENTS p53 Mutations and c-erbB-2 Amplification in Intraductal and Invasive Breast Carcinomas of High Histologic Grade H. Tsuda, K. Iwaya, T. Fukutomi and S. Hirohashi Deletion Mapping of Chromosome Ip and 22q in Pheochromocytoma E. Shin, S. Fujita, K. Takami, H. Kurahashi, Y. Kurita, T. Kobayashi, T. Mori, I. Nishisho and S. Takai The Expression of Invasive Behavior of Differentiated Squamous Carcinoma Cell Line Evaluated by an in vitro Invasion Model E. Kawahara, Y. Okada, I. Nakanishi, K. Iwata, S. Kojima, S. Kumagai and E. Yamamoto A Case of Squamous Cell Lung Carcinoma with High Concentration of Parathyroid Hormone-related Peptide in Serum and Pleural Effusion Presenting Hypercalcemia H. Iguchi, H. Katakami, Y. Ichinose, Y. Nishi, S. Tanaka, N. Hara, M. Ohta, M. Haji and H. Nawata Enhancing Effect of Interleukin-2 on Production of Parathyroid Hormone-related Protein by Adult T-Cell Leukemia Cells N. Mori, K. Ohsumi, S. Murakami, A. Wake, F. Shirakawa, I. Morimoto, S. Oda and S. Eto Interleukin-2 Prevents Programmed Cell Death in Adult T-Cell Leukemia Cells H. Tsuda, R.-W. Huang and K. Takatsuki Effect of Accessory Cells on Stimulation of Murine T-Cell Leukemia with Antibodies to the CD3/T Cell Antigen Receptor Complex R. Suto, H. Udono, A. Yamamoto, H. Shiku and E. Nakayama Enhancement of Cytosine Arabinoside Cytotoxicity by Granulocyte/Macrophage Colony-stimulating Factor and Granulocyte Colony-stimulating Factor in a Human Myeloblastic Leukemia Cell Line R. Takauji, K. Tohyama, T. Ueda and T. Nakamura Lysosome Labilizers Potentiate the Antitumor Effects of Tumor Necrosis Factor-a T. Masegi, A. Kato, K. Kitai, M. Fukuoka, K. Soma, Y. Ichikawa, S. Nakamura, N. Watanabe and Y Niitsu Effects of Chemoendocrine Therapy on the Coagulation-Fibrinolytic Systems in Patients with Advanced Breast Cancer Japan Advanced Breast Cancer Study Group and Japan Clinical Oncology Group Inhibition of Cisplatin-mediated DNA Damage in vitro by Ribonucleotides S. Seki, A. Hongo, B. Zhang, K. Akiyama, A. H. Sarker and T. Kudo Pharmacokinetic Evaluation of (Glycolato-O,O’ )diammine Platinum(II) in Lung Lymph in Sheep T. Koizumi, K. Kubo, S. Shinozaki, S. Koyama, T. Amari, T. Hayano, K. Fujimoto, T. Kobayashi, M. Sekiguchi, R. Sakai, T. Ohshima and K. Miyamoto Ductectatic-type Mucinous Cystadenoma and Cystadenocarcinoma of the Human Pancreas: A Novel Clinicopathological Entity A. Yanagisawa, K. Ohashi, M. Hori, K. Takagi, T. Kitagawa, H. Sugano and Y. Kato 481-588 RAPID COMMUNICATIONS Strong Inhibition of 2-Amino-6-methyldipyrido[ 1,2-a:3',2’-d]imidazole-induced Mutagenesis and Hepatocarcinogenesis by 1-O-Hexyl-2,3,5-trimethylhydroquinone M. Hirose, K. Akagi, R. Hasegawa, T. Satoh, Y. Nihro, T. Miki, T. Sugimura and N. Ito Carboxyl-terminal Heparin-binding Fragments of Platelet Factor 4 Retain the Blocking Effect on the Receptor Binding of Basic Fibroblast Growth Factor Y. Sato, M. Waki, M. Ohno, M. Kuwano and T. Sakata Enhancement of Reversing Effect of Cyclosporin A on Vincristine Resistance by Anti-P-glycoprotein Monoclonal Antibody MRK-16 M. Naito, H. Tsuge, C. Kuroko, A. Tomida and T. Tsuruo JPN. J. CANCER RES. 84, 1993 Atypical Mitosis in Gastric Intestinal Metaplasia in Japanese Patients C. A. Rubio, Y. Kato and T. Kitagawa REGULAR PAPERS Effect of Experimental Hypochlorhydria on the Histological Differentiation of Adenocarcinomas in the Canine Stomach T. Sano, O. Kobori, S. Kuroki, H. Nagawa and T. Muto Different Effects of Regenerative and Direct Mitogenic Stimuli on the Growth of Initiated Cells in the Resistant Hepatocyte Model P. Coni, G. Pichiri-Coni, M. Curto, G. Simbula, L. Giacomini, D. S. R. Sarma, G. M. Ledda-Columbano and A. Columbano Elevated Level of 8-Hydroxydeoxyguanosine in DNA of Liver, Kidneys, and Brain of Long-Evans Cinnamon Rats F. Yamamoto, H. Kasai, Y. Togashi, N. Takeichi, T. Hori and S. Nishimura N-Nitroso-N-ethylurea-induced Hamster Melanoma: A New Method for Efficient Induction and Schwannian Differentiation of Melanoma T. Nemoto, T. Nakamura, K. Ohashi and T. Kasuga The Murine cot Proto-oncogene: Genome Structure and Tissue-specific Expression R. Ohara, J. Miyoshi, M. Aoki and K. Toyoshima Genetic Alterations in Thyroid Tumor Progression: Association with p53 Gene Mutations T. Ito, T. Seyama, T. Mizuno, N. Tsuyama, Y. Hayashi, K. Dohi, N. Nakamura and M. Akiyama Molecular Cloning of 19p13 Breakpoint Region in Infantile Leukemia with t(11;19)(q23;p13) Translocation S. Iida, M. Seto, K.Y amamoto, H. Komatsu, Y. Akao, S. Nakazawa, Y. Ariyoshi, T. Takahashi and R. Ueda Inhibitory Effects of Sizofiran on Anticancer Agent- or X-Ray-induced Sister Chromatid Exchanges and Mitotic Block in Murine Bone Marrow Cells Z. Yang, Y. Tsuchiya, T. Arika and M. Hosokawa Detection of Active Form of Transforming Growth Factor in Cerebrospinal Fluid of Patients with Glioma T. Tada, K. Yabu and S. Kobayashi Augmented Expression of a Type IV Collagen-binding Protein in a Highly Metastatic Murine Fibrosarcoma Clone K. Kogawa, Y. Mogi, T. Takayama, K. Koike, N. Yoshizaki, H.M uramatsu and Y. Niitsu Antimetastatic Activity of Polymeric RGDT Peptides Conjugated with Poly(ethylene glycol) I. Saiki, J. Yoneda, Y. Igarashi, M. Aoki, N. Kusunose, K. Ono and I. Azuma DNA Damage and Cell Killing by Camptothecin and Its Derivative in Human Leukemia HL-60 Cells A. Yoshida, T. Ueda, Y. Wano and T. Nakamura ED-110, a Novel Indolocarbazole, Prevents the Growth of Experimental Tumors in Mice H. Arakawa, T. Iguchi, T. Yoshinari, K. Kojiri, H. Suda and A. Okura Enhancement of Ultrasonically Induced Cell Damage by a Gallium-Porphyrin Complex, ATX-70 S. Umemura, N. Yumita and R. Nishigaki 589-702 RAPID COMMUNICATION Potentiation of Metastatic Capacity by Transforming Growth Factor-81 Gene Transfection N. Ueki, T. Ohkawa, Y. Yokoyama, J. Maeda, Y. Kawai, T. Ikeda, Y. Amuro, T. Hada and K. Higashino CONTENTS REGULAR PAPERS Protective Effects of Raw Vegetables and Fruit against Lung Cancer among Smokers and Ex-smokers: A Case-Control Study in the Tokai Area of Japan C. Gao, K. Tajima, T. Kuroishi, K. Hirose and M. Inoue Lung Cancer Incidence Rate for Male Ex-smokers According to Age at Cessation of Smoking T. Sobue, N. Yamaguchi, T. Suzuki, I. Fujimoto, M. Matsuda, O. Doi, T. Mori, K. Furuse, M. Fukuoka, T. Yasumitsu, O. Kuwahara, M. Ichitani, T. Taki, M. Kuwabara, K. Nakahara, S. Endo, K. Sawamura, M. Kurata and S. Hattori High Frequency of Thyroid Tumor Induction by N-Methyl-N’-nitro-N-nitrosoguanidine in the Hermaphroditic Fish Rivulus marmoratus E.-H. Park, H.-H. Chang, K.-C. Lee, H.-S. Kweon, O.-S. Heo and K.-W. Ha Deletion of WTI and WITI Genes and Loss of Heterozygosity on Chromosome 11p in Wilms Tumors in Japan Y. Kaneko, O. Takeda, C. Homma, N. Maseki, H. Miyoshi, Y. Tsunematsu, B. G. Williams, G. F. Saunders and M. Sakurai Changes of Proliferative Activity and Phenotypes in Spontaneous Differentiation of a Colon Cancer Cell Line A. Hara, T. Hibi, M. Yoshioka, K. Toda, N. Watanabe, A. Hayashi, Y. Iwao, H. Saito, T. Watanabe and M. Tsuchiya Increased Cell-surface Urokinase in Advanced Ovarian Cancer H. Kobayashi, N. Moniwa, M. Sugimura, H. Shinohara, H. Ohi and T. Terao Development and Characterization of a Novel Anti-fucosylated Antigen Monoclonal Antibody YB-2 and Its Usefulness in the Immunohistochemical Diagnosis of Colorectal Cancer S. Yazawa, S. Akamatsu, T. Tachikawa, H. Naito, J. Nakamura, T. Asao, Y. Nagamachi, T. Nakajima, S. Shin and D. Chia Transforming Growth Factor-a Expression of Renal Proximal Tubules in Wistar Rats Treated with Ferric and Aluminum Nitrilotriacetate J. Deguchi, T. Kawabata, A. Kondo and S. Okada Inhibitory Effect of a Somatostatin Analogue (SMS 201-995) on the Growth of An¢rogen-dependent Mouse Mammary Tumor (Shionogi Carcinoma 115) S. Noguchi, Y. Nishizawa, K. Motomura, H. Inaji, S. Imaoka, H. Koyama and K. Matsumotc Human Cervical Epidermal Carcinoma-associated Intracellular Localization of Glycosphingolipid with Blood Group A Type 3 Chain Y. Cui, H. Noguchi, K. Kiguchi, D. Aoki, N. Susumu, S. Nozawa, H. Kawakami, H. Hirano and M. Iwamori Cellular Stress- and Transformation-associated Cell Surface Antigens Expressed on Human and Rodent Tumor Cells T. Torigoe, N. Tsuboi, Y. Wada, W. Qi, S. Ohtani, A. Kishi, N. Sato and K. Kikuchi Potentiation of in vivo Antitumor Effects of Recombinant Interleukin-1a@ by Gelatin Conjugation Y. Tabata, K. Uno, Y. Ikada, T. Kishida and S. Muramatsu Interferon-7-producing Tumor Induces Host Tumor-specific T Cell Responses Y. Teramura, Y. Watanabe, N. Kan, T. Masuda and K. Kuribayashi Relationship between Development of Diarrhea and the Concentration of SN-38, an Active Metabolite of CPT-11, in the Intestine and the Blood Plasma of Athymic Mice Following Intraperitoneal Administration of CPT-11 E. Araki, M. Ishikawa, M. ligo, T. Koide, M. Itabashi and A. Hoshi JPN. J. CANCER RES. 84, 1993 703-820 RAPID COMMUNICATION Relationships among Tenascin Expression, DNA Ploidy Patterns, and Multidrug Resistance Gene Product (P-Glycoprotein) in Human Colon Carcinoma I. Sugawara, J. Hirakoshi, M. Kusakabe, A. Masunaga, S. Itoyama and T. Sakakura REGULAR PAPERS A Hospital-based Case-Control Study on Hepatocellular Carcinoma in Fukuoka and Saga Prefectures, Northern Kyushu, Japan K. Fukuda, A. Shibata, I. Hirohata, K. Tanikawa, G. Yamaguchi and M. Ishii HTLV-I, HIV-I, and Hepatitis B and C Viruses in Western Province, Papua New Guinea: A Serological Survey K. Yamaguchi, T. Inaoka, R. Ohtsuka, T. Akimichi, T. Hongo, T. Kawabe, M. Nakazawa, M. Futatsuka and K. Takatsuki Effect of Physical Exercise on the Content of 8-Hydroxydeoxyguanosine in Nuclear DNA Prepared from Human Lymphocytes T. Inoue, Z. Mu, K. Sumikawa, K. Adachi and T. Okochi Loss of VLA-2 Collagen Receptor in Breast Carcinoma, Facilitating Invasion and Metastasis K. Arihiro, K. Inai, K. Kurihara, S. Takeda, M. Kaneko, K. Kuroi and T. Toge Long-term Preservation of Renin-secreting Ability by Human Adult Juxtaglomerular Tumor Cells in Explant Culture U. Armato, D. D’Agostino, F. Romano, A. Salvetti and F. Mantero Lack of Correlation between the Gap Junctional Communication Capacity of Human Colon Cancer Cell Lines and Expression of the DCC Gene, a Homologue of a Cell Adhesion Molecule (N-CAM) M. Mesnil, C. Piccoli, J.-L. Klein, I. Morand and H. Yamasaki Head and Neck Carcinomas in Patients under the Age of Forty Years M. Tsukuda, K. Ooishi, I. Mochimatsu and H. Sato Levels of Complement Regulatory Molecules in Lung Cancer: Disappearance of the D17 Epitope of CD55 in Small-cell Carcinoma T. Sakuma, K. Kodama, T. Hara, Y. Eshita, N. Shibata, M. Matsumoto, T. Seya and Y. Mori A Novel Human Monoclonal Antibody Directed to a Tumor-associated Antigen T. Kudo, S. Kobayashi, K. Murakami, R. Takano, M. Nose, N. Sato, H. Saeki, S. Saijyo, S. Hiyamuta, A. Kadota and T. Tachibana Generation of Monoclonal Antibodies to the Rabbit Interleukin-2 Receptor @ Chain (CD25) and Its Distribution in HTLV-1-transformed Rabbit T Cells M. Kotani, Y. Yamamura, M. Tsudo, T. Tamatani, F. Kitamura and M. Miyasaka Expression Behavior of 85-kDa Membrane Protein in Adriamycin-resistant Tumor Cells and the Inhibition of Human Tumor Growth in Athymic Mice by MRK-20 Monoclonal Antibody against the Protein S. Ishii, M. Naito and T. Tsuruo Effect of 5-Fluorouracil and UFT on Experimental Liver Metastasis Model of Colorectal Cancer Using Mouse Colon 26 Cells T. Tominaga, Y. Yoshida, G. Kosaki and M. Kurihara Enhancement of Antitumor Activity of Cisplatin on Human Gastric Cancer Cells in vitro and in vivo by Buthionine Sulfoximine Y. Saikawa, T. Kubota, T.-H. Kuo, T. Furukawa, H. Tanino, M. Watanabe, K. Ishibiki and M. Kitajima CONTENTS Synergistic Antitumor Effects of Carboplatin and Interferons on Hepatic Metastases of Colon Carcinoma 26 and M5076 Reticulum Cell Sarcoma M. ligo, I. Shimizu and K. Sagawa Stereo(C7)-dependent Topoisomerase II Inhibition and Tumor Growth Suppression by a New Quinolone, BO-2367 T. Yoshinari, E. Mano, H. Arakawa, M. Kurama, T. Iguchi, S. Nakagawa, N. Tanaka and A. Okura Improved Detection Rate of Early Breast Cancer in Mass Screening Combined with Mammography N. Ohuchi, K. Yoshida, M. Kimura, A. Ouchi, S. Kamioki, K. Shiiba, N. Matoba, S. Kojima, K. Takahashi, S. Matsuno, A. Fukao, R. Abe and S. Mori Rapid Diagnosis of Gastric Malignant Lymphoma from Biopsy Specimens: Detection of Immunoglobulin Heavy Chain Rearrangement by Polymerase Chain Reaction H. Ono, H. Kondo, D. Saito, S. Yoshida, K. Shirao, H. Yamaguchi, T. Yokota, K. Hosokawa, H. Fukuda, S. Hayashi, A. Ochiai and Y. Oguro LETTER TO THE EDITOR Unusual Interactions of Adenovirus 5 and 12 E1B Proteins with p53 A. J. van der Eb 821-927 Perspectives on Cancer in Japan and the United States S. Broder RAPID COMMUNICATIONS HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis-like Rats by Intravenous Injection of HTLV-1-producing Rabbit or Human T-Cell Line into Adult WKA Rats S. Kushida, M. Matsumura, H. Tanaka, Y. Ami, M. Hori, M. Kobayashi, K. Uchida, K. Yagami, T. Kameyama, T. 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Hayashi Effects of Chronic Administration of Low Doses of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline on Glutathione S-Transferase Placental Form-positive Foci Development in the Livers of Rats Fed a Choline-deficient Diet H. Sone, K. Wakabayashi, H. Kushida, M. Ochiai, T. Sugimura and M. Nagao JPN. J. CANCER RES. 84, 1993 Inhibitory Effects of Benzyl Isothiocyanate and Benzyl Thiocyanate on Diethylnitrosamine-induced Hepatocarcinogenesis in Rats S. Sugie, A.O kumura, T. Tanaka and H. Mori Analysis of Oncogenes and Tumor Suppressor Genes in Human Breast Cancer H. Yamashita, S. Kobayashi, H. Iwase, Y. Itoh, T. Kuzushima, H. Iwata, K. Itoh, A. Naito, T. Yamashita, A. Masaoka and N. Kimura Expression of Amphiregulin, a Novel Gene of the Epidermal Growth Factor Family, in Human Gastric Carcinomas Y. Kitadai, W. Yasui, H. Yokozaki, H. Kuniyasu, A. Ayhan, K. Haruma, G. Kajiyama, G. R. Johnson and E. Tahara c-Myc Selectively Regulates the Latent Period and Erythroid-specific Genes in Murine Erythroleukemia Cell Differentiation W. Shoji, Y. Ohmori and M. Obinata Genetic Changes and Histopathological Grades in Human Hepatocellular Carcinomas M. Konishi, R. Kikuchi-Yanoshita, K. Tanaka, C. Sato, K. Tsuruta, Y. Maeda, M. Koike, S. Tanaka, Y. Nakamura, N. Hattori and M. Miyaki Infiltrating Lymphocytes and Accessory Cells in Nasopharyngeal Carcinoma Y.-S. Zong, C.-Q. Zhang, F. Zhang, J.-B. Ruan, M.-Y. Chen, K.-T. Feng and Z.-F. Yu Brefeldin A Blocks the Cytotoxicity of T Cell Receptor c/ and 7/ö Cytotoxic T Lymphocyte Clones Reacting against Human Autologous Cancer Cells Y. Wada, H. Ikeda, D. Ueda, M. Ohta, S. Takahashi, K. Hirata, N. Sato and K. Kikuchi Enhanced Tumor Localization of Radiolabeled Fab Fragments of Monoclonal Antibody A7 in Nude Mice Bearing Human Pancreatic Carcinoma Xenografts E. Otsuji, T. Yamaguchi, N. Yamaoka, M. Kato, T. Kotani, K. Kitamura, N. Yamaguchi and T. Takahashi Enhanced Antitumor Effect of Recombinant Human Tumor Necrosis Factor in Combination with Recombinant Human Granulocyte Colony-stimulating Factor in BALB/c Mice M. Maeda, N. Watanabe, N. Tsuji, Y. Tsuji, T. Okamoto, H. Sasaki, S. Akiyama and Y. Niitsu 929-995 REVIEW Guidelines for Analysis and Reporting of Clinical Trials in Oncology S. Piantadosi, N. Saijo and T. Tamura REGULAR PAPERS Benign Breast Disease as a Breast Cancer Risk in Japanese Women Y. Nomura, H. Tashiro and Y. Katsuda Enhancing Effects of Calcium-deficient Diet on Gastric Carcinogenesis by N-Methyl-N -nitro-N-nitroso- guanidine in Wistar Rats M. Tatsuta, H. lishi, M. Baba, H. Uehara, A. Nakaizumi and H. Taniguchi Enhancing Effects of Estrogens on Endometrial Carcinogenesis Initiated by N-Methyl-N-nitrosourea in ICR Mice K. Niwa, T. Murase, T. Furui, S. Morishita, H. Mori, T. Tanaka, H. Mori and T. 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