Intestinal Anisakiasis in Japan: Infected Fish, Sero-Immunological Diagnosis, and Prevention

260 Pages·1990·8.44 MB·English

by  H. Ishikura (auth.)

H.Ishikura K. Kikuchi (Eds.)
Intestinal
Anisakiasis in Japan
Infected Fish, Sero-Immunological
Diagnosis, and Prevention
With 109 Figures, 27 in Color
Springer-Verlag
Tokyo Berlin Heidelberg
New York London Paris
Hong Kong Barcelona
HAJIME ISHIKURA
Honorary Member of the Japanese Society of Clinical Surgery
Director, The Ishikura Hospital
Iwanai, 045 Japan
KOKICHI KIKUCHI
President and
Professor, Department of Pathology
Sapporo Medical College
Sapporo, 060 Japan
ISBN-13:978-4-431-68301-8 e-ISBN-13:978-4-431-68299-8
DOl: 10.1 007/978-4-431-68299-8
Library of Congress Cataloging-in-Publication Data
Intestinal anisakiasis in Japan: infected fish, sero-immunological diagnosis,
and prevention / H. Ishikura, K. Kikuchi (eds.). p. cm. Includes bibliog
raphical references. Includes index. ISBN-13:978-4-431-68301-8:
DM234.00 (approx.) 1. Anisakiasis. 2. Intestines-
Infections. I. Ishikura, H. (Hajime), 1914- . II. Kikuchi, Kokichi.
[DNLM: 1. Immunologic Tests. 2. Intestinal Diseases, Parasitic-
. diagnosis. 3. Intestinal Diseases, Parasitic-prevention & control
Japan. 4. Nematode Infections-diagnosis. 5. Nematode Infections
prevention & control-Japan. WC 850 161]. RC840.A56158 1990.
616.9'654-dc20. DNLMlDLC. 90-10120
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© Springer-Verlag Tokyo 1990
Softcover reprint of the hardcover 1st edition 1990
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Typesetting: Asco Trade Typesetting Ltd., Hong Kong
Preface
This monograph follows the previously published "Gastric Anisa
kiasis in Japan." As is well-known from experimental examination,
the pathogenic species of Anisakidae larvae are Anisakis simplex,
Anisakis physeteris, Pseudoterranova decipiens, and Contracaecum
osculatum sp., but only Anisakis simplex larvae get into the human
intestinal wall by the consumption of raw paratenic host fish and
squid. Normally, this larva is not only paratenic in the tissue of the
gastrointestinal tract but may also invade the peritoneal or thoracic
cavity, causing extra-gastrointestinal anisakiasis.
The fulminant form of gastric anisakiasis is diagnosed by gas
trofiberscopy with larvae easily removed endoscopically. The mild
form of gastric anisakiasis which produces a tumor (granuloma) is
diagnosed by biopsy using a gastrofiberscope.
However, intestinal anisakiasis is hard to diagnose, and when the
fulminant form of intestinal anisakiasis is clinically suspected, roent
genographic, ultrasonographic or seroimmunological examination
should be performed.
Intestinal anisakiasis may produce severe symptoms of ileus due to
an Arthus-type allergic reaction. However, an emergency lapar
otomy is not always necessary.
There are rare mild cases in which the tumor is found in the intes
tinal wall by roentgenography, and is sometimes misdiagnosed as a
neoplasm ..
The total number of intestinal anisakiasis cases reported in Japan is
567, with most of these of the fulminant form.
This monograph explains intestinal anisakiasis from several view
points. Recent morphological findings and advances in larvae iden
tification have helped in warning of new causative species.
We hope "to deal with the different kinds of paratenic hosts which
are captured in the neighboring waters of Japan.
Histopathological and seroimmunological findings with improved
technology have helped to establish the specific monoclonal antibody
of Anisakis simplex larva as a new method of immune diagnosis.
Studies on eosinophilia and lymphokine are included to further
clarify the subject.
vi Preface
Finally, we hope this book will be of help to doctors who are in
terested in intestinal anisakiasis and Anisakidae itself.
HAJIME ISHIKURA
KOKICHI KIKUCHI
Table of Contents
Introduction
H. ISHIKURA ................................................. 1
Epidemiological Aspects of Intestinal Anisakiasis and Its
Pathogenesis
H. ISHIKURA ................................................. 3
Anisakis Larvae in Intermediate and Paratenic Hosts in Japan
K. NAGASAwA. . . . . .. . . . .. . . . . . . . .. . . . . .. . . . . . .. . . . . . . . . .. . .. . 23
The Life Cycle of Anisakis simplex: A Review
K. NAGASAwA................................................ 31
Prevalence of Larval Anisakid Nematodes
in Fresh Fish from Coastal Waters of Hokkaido
K. MIYAMOTO. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
Infection Rate of Anisakinae Larvae in Fish Taken from the
Offing of Ishikawa Prefecture
Y. OIKAWi\, T. IKEDA. . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . .. . . . . . . . . 45
Anisakinae in Sanin Waters of the Japan Sea
J. MAEJIMA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
Anisakinae in the Seto Inland Sea
T. An, T. FUKUDA, Y. TONGU ................................ 57
Survey of Anisakidae Larvae from Marine Fish Caught in the
Sea Near Kyushu Island, Japan
Y. TAKAO.................................................... 61
Surface Ultrastructure of Anisakidae Larvae
Y. TONGU, T. FUKUDA, T. AJI ................................ 73
Restriction Endonuclease Analysis of Anisakis Genome
K. SUGANE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81
Clinical Features of Intestinal Anisakiasis
H.IsHIKURA ................................................. 89
viii Table of Contents
Radiographic Features of Intestinal Anisakiasis
T. MATSUI, M.IIDA, M. FUJISHIMA, T. YAO.................... 101
Diagnosis of Intestinal Anisakiasis by Ultrasonography
T. YAMAMOTO, K. MINAMI.................................... 109
Differential Diagnosis of Intestinal Anisakiasis
H.IsHIKURA ................................................. 119
Pathology of Intestinal Anisakiasis
Y. KIKUCHI, H. ISHIKURA, K. KIKUCHI......................... 129
Clinical Patho-Parasitology of Extra-Gastrointestinal
Anisakiasis
H. yOSHIMURA............................................... 145
Immunodiagnosis for Intestinal Anisakiasis
M. TSUJI. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155
Skin (Intradermal) Testing Using Several Kinds of Anisakis
Larva Antigens
H. ISHIKURA, Y. KIKUCHI, O. TOYOKAWA, H. HAYASAKA,
K. KIKUCHI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159
Passive Hemagglutination Test (Boyden)
K. ASAIsm, C. NISHINO, H. HAYASAKA. . . . . . . . . . . . . . . . . . . . . . . . 167
Immune Adherence (IA), Sarles Phenomenon (SP) and
Diffusion Chamber Method (DC)
H. ISHIKURA, Y. KIKUCHI, O. TOYOKAWA, H. HAYASAKA,
K. KIKUCHI.................................................. ·173
Ouchterlony Test and Immunoelectrophoresis
M. TSUJI. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183
Immunodiagnosis for Anisakiasis with Detection of IgE
Antibody to Human Anisakiasis by Enzyme-Linked
Immunosorbent Assay
Y. TAKEMOTO, M. TSUJI, Y. IWANAGA . . . . . .. . . . . . . . . . . . . . . . . . . 187
Detection of Cellular Immunity by Migration Inhibition Test
on Rabbits and Guinea Pigs Immunized with Anisakis Larval
Antigens
Y. KIKUCHI, H. SAEKI, H. ISHIKURA ........................... 191
Measurement by ELISA of Anisakis-Specific Antibodies of
Different Immunoglobulin Classes in Paired Sera of Gastric
Anisakiasis
N. AKAo..................................................... 199
Detection of Anti-Anisakis Antibody of IgE Type in Sera of
Patients with Intestinal Anisakiasis
Y. YAMAMOTO, H. NAKATA, Y. yAMAMOTO..................... 205
Table of Contents ix
Development of Monoclonal Antibodies Reacting with
Anisakis simplex Larvae
S. TAKAHASHI, A. YAGIHASHI, N. SATO, K. KIKUCHI............ 217
Serodiagnosis of Intestinal Anisakiasis Using Micro-ELISA
Diagnostic Significance of Patients' IgE
S. TAKAHASHI, A. YAGIHASHI, N. SATO, K. KIKUCHI............ 221
Mechanism of Eosinophilia in Parasitic Infection with Special
Emphasis on the Eosinophil Chemotactic Lymphokines
Directed Against Different Maturation Stages of Eosinophils
Y. NAWA, M. OWHASHI, H. MARUYAMA. . . . . . . . . . . . . . . . . . . . . . . 225
Antigenicity of the Cuticle with Emphasis on the Immuno
cytochemical Approach
Y. TAKAHASHI, T. ARAKI..................................... 239
Immune Response to Anisakis Larvae in Healthy Humans
C. NISHINO, K. ASAISHI, H. HAYASAKA........................ 251
Conclusion
H. ISHIKURA, K. KIKUCHI. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257
Subject Index. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259
List of Contributors
* An, TOSHIKI Department of Parasitology, Okayama
University Medical School, Okayama, 700
Japan
* AKAo, NOBUAKI Assistant Professor, Department of Para
sitology, School of Medicine Kanazawa
University, Kanazawa, 920 Japan
ARAKI, TsuNEn Professor, Department of Parasitology,
Nara Medical University, Kashihara, Nara,
634 Japan
* ASAISHI, KAZUAKI Assistant Professor, The First Department
of Surgery, Sapporo Medical College and
Hospital, Sapporo, 060 Japan
FUJISHIMA, MASATOSHI Professor, The Second Department of Inter
nal Medicine, Faculty of Medicine, Kyushu
University, Fukuoka, 812 Japan
FUKUDA, TOMIO Okayama Fisheries Experimental Station,
Okayama, 700 Japan
HAYASAKA, HIROSHI Honorary Professor, The First Department
of Surgery, Sapporo Medical College and
Hospital, Sapporo, 060 Japan
IIDA, MITSUO Lecturer, The Second Department of Inter
nal Medicine, Faculty of Medicine, Kyushu
University, Fukuoka, 812 Japan
IKEDA, TERUAKI Assistant Professor, Department of Medical
Zoology, Kanazawa Medical University,
Uchinada, Kahoku, Ishikawa, 920-02 Japan
* ISHIKURA, HAJIME Honorary Member of Japanese Society of
Clinical Surgery, Director, The Ishikura
Hospital, Iwanai, Hokkaido, 045 Japan
Xli List of Contributors
IWANAGA, YUZURU Assistant Professor, Department of Para
sitology, School of Medicine, Hiroshima
University, Hiroshima, 734 Japan
KIKUCHI, KOKICHI President and Professor, Department of
Pathology, Sapporo Medical College, Sap
poro, 060 Japan
* KIKUCHI, YUKO Director, Sapporo City Institute of Public
Health, Sapporo, 003 Japan
* MAEJIMA, JOJI Lecturer, Department of Medical Zoology,
Tottori University, School of Medicine,
Yonago, 683 Japan
MARUYAMA, HARUHIKO Department of Parasitology, Miyazaki
Medical College, Kiyotake, Miyazaki,
889-16 Japan
* MATSUI, TOSHIYUKI Assistant Professor, Fukuoka University
School of Medicine, Chikushi Hospital, Chi
kushino, 818 Japan
MINAMI, KOUHEI Section of Internal Medicine, Niwa Hospi
tal, Odawara, 406 Japan
* MIYAMOTO, KENJI Assistant Professor, Department of Para
sitology, Asahikawa Medical School, Asahi
kawa, 078 Japan
*NAGASAWA, KAZUYA Hokkaido Fisheries Experimental Station,
Yoichi, Hokkaido, 046 Japan
NAKATA, HIROFUMI The First Department of Internal Medicine,
Kochi Medical School, Nangoku, 781-51
Japan
*NAWA, YUKIFUMI Professor, Department of Parasitology,
Miyazaki Medical College, Kiyotake,
Miyazaki, 889-16 Japan
* NISHINO, CHISATO Assistant Professor, The First Department
of Surgery, Sapporo Medical College and
Hospital, Sapporo, 060 Japan
*OIKAWA, YOSABURO Department of Medical Zoology, Kanazawa
Medical University, Uchinada, Kahoku,
Ishikawa, 920-62 Japan
OWHASHI, MAKOTO Department of Parasitology, Miyazaki
Medical College, Kiyokake, Miyazaki,
889-16 Japan
SAEKI, HISASHI Director, Saeki Surgical Hospital, Shiro
ishi-ku, Sapporo, 004 Japan