International position paper on women's health and menopause: a comprehensive approach PDF
Preview International position paper on women's health and menopause: a comprehensive approach
N"a t i o n a I Heart, Lung, and Blood Institute Office of Research on Women’s Health Giovanni Lorenzini Medical Science Foundation International Position Paper on Women’s Health AND Menopause: A Comprehensive Approach International Position Paper on Women’s Health AND Menopause: A Comprehensive Approach NAIiONAL iMSTlTUTES OF HEALTH NIH AUG 2 4 2002 1 BLDG 10, IT C.TFTCr' DR. nr"!"! 'j Kfl National Heart, Lung, AND Blood Institute Oeeice of Research on Women’s Health National Institutes of Health AND Giovanni Lorenzini Medical Science Foundation NIH Publication No. 02-3284 July 2002 CHAIRS AND EDITORS Chair and Editor Cochair and Coeditor Nanette K. Wenger, M.D. Claude J. M. Lenfant, M.D. Professor ofMedicine (Cardiology) Director Emory University School of Medicine National Heart, Lung, and Blood Institute Atlanta, GA, U.S.A. National Institutes ofHealth Bethesda, MD, U.S.A. Cochair and Coeditor Rodolfo Paoletti, M.D. Cochair and Coeditor Professor ofPharmacology Vivian W. Pinn, M.D. Director, Department of Pharmacological Sciences Associate Director for Research on University of Milan Women’s Health Milan, Italy Director, Office of Research on Women’s Health National Institutes of Health Bethesda, MD, U.S.A. PANEL MEMBERS Elizabeth Barrett-Connor, M.D. Louise A. Brinton, Ph.D. Professor and Chief Chief, Environmental Epidemiology Branch Division ofEpidemiology National Cancer Institute Department of Family and Preventive Medicine National Institutes of Health University of California, San Diego School of Bethesda, MD, U.S.A. Medicine La Jolla, CA, U.S.A. Aila Collins, Ph.D. Associate Professor Martin H. Birkhauser, M.D. Psychology Section Professor Department of Clinical Neuroscience Division of Gynecological Endocrinology Karolinska Institute Department of Obstetrics and Gynecology Stockholm, Sweden University of Bern Bern, Switzerland II Peter Collins, M.D. Susan Hendrix, D.O. Reader and Honorary Consultant Cardiologist Associate Professor Imperial College School ofMedicine and Royal Division of Gynecology Brompton Hospital Department of Obstetrics and Gynecology London, United Kingdom Wayne State University School ofMedicine Hutzel Hospital Pier Giorgio Crosignani, M.D. Detroit, MI, U.S.A. Professor and Chairman First Department of Obstetrics and Gynecology Carlo La Vecchia, M.D. University ofMilan Head, Laboratory ofEpidemiology Milan, Italy Mario Negri Institute for Pharmacological Research Lorraine Dennerstein, A.O., M.B.B.S., Ph.D., Professor ofEpidemiology D.P.M., F.R.A.N.Z.C.P. University ofMilan Professor and Director Milan, Italy Office for Gender and Health Department ofPsychiatry Robert Lindsay, M.D., Ph.D. University ofMelbourne Chairman of Medicine Royal Melbourne Hospital Helen Hayes Hospital Parkville, VIC, Australia Professor of Clinical Medicine College of Physicians and Surgeons Bruce Ettinger, M.D. Columbia University Senior Investigator New York, NY, U.S.A. Division ofResearch Kaiser Permanente Medical Care Program Adriana Maggi, Ph.D. Oakland, CA, U.S.A. Professor ofBiotechnology and Pharmacology Director, Molecular Pharmacology Laboratory Jan-Ake Gustafsson, M.D., Ph.D. Department ofPharmacological Sciences Professor and Chairman University ofMilan Department ofMedical Nutrition Milan, Italy Chairman, Department ofBiosciences Karolinska Institute Joan A. McGowan, Ph.D. Novum, Huddinge University Hospital Director, Musculoskeletal Diseases Branch Huddinge, Sweden National Institute ofArthritis and Musculoskeletal and Skin Diseases VictorW. Henderson, M.D., M.S. National Institutes ofHealth Professor Bethesda, MD, U.S.A. Departments of Geriatrics and Neurology Donald W. Reynolds Center onAging Alzheimer’s Disease Center University ofArkansas for Medical Sciences Little Rock, AR, U.S.A. Anne McTieman, M.D., Ph.D. Susan M. Resnick, Ph.D. Associate Member Investigator Public Health Sciences Division Cognition Section Fred Hutchinson Cancer Research Center Laboratory ofPersonality and Cognition Research Associate Professor National Institute on Aging Department ofEpidemiology National Institutes of Health University ofWashington Schools ofMedicine and Baltimore, MD, U.S.A. Public Health and Community Medicine Seattle, WA, U.S.A. Jacques E. Rossouw, M.D. Acting Director, Women’s Health Initiative Maryann Redford, D.D.S., M.P.H. National Heart, Lung, and Blood Institute Director, Clinical Trials and Epidemiologic National Institutes of Health Studies Program Bethesda, MD, U.S.A. National Institute ofDental and Craniofacial Research Sherry Sherman, Ph.D. National Institutes of Health Director, Clinical Endocrinology and Bethesda, MD, U.S.A. Osteoporosis Research National Institute on Aging National Institutes of Health Bethesda, MD, U.S.A. NONPANEL COAUTHORS Janet R. Guthrie, Ph.D., M.Sc. Stefan Nilsson, Dr. Med. Sci. Research Fellow Associate Professor Office for Gender and Health Affiliated to Department of Medical Nutrition Department of Psychiatry Karolinska Institute Faculty of Medicine, Dentistry, and Novum, Huddinge University Hospital Health Sciences Huddinge, Sweden The University ofMelbourne Parkville, VIC, Australia Nanette Santoro, M.D. Division Director Barbara E. K. Klein, M.D., M.P.H. Division ofReproductive Endocrinology Professor of Ophthalmology and Visual Sciences Department of Obstetrics, Gynecology, and Ocular Epidemiology Women’s Health University ofWisconsin-Madison Albert Einstein College of Medicine Madison, WI, U.S.A. Bronx, NY, U.S.A. IV WITH APPRECIATION FOR THE EXPERTISE OF THE FOLLOWING, WHO GRACIOUSLY REVIEWED AND COMMENTED ON THE PRELIMINARY INDIVIDUAL CHAPTERS: Beth Alder, Ph.D. Silvia Franceschi, M.D. Professor and Director of Research Chief, Unit of Field and Intervention Studies Faculty of Health and Life Sciences International Agency for Research on Cancer Napier University Lyon Cedex, France Edinburgh, United Kingdom Ulysses J. Gaspard, M.D., Ph.D. GloriaA. Bachmann, M.D. Professor and Chief Professor Service of Gynecology Department of Obstetrics and Gynecology University Center ofLiege Robert Wood Johnson Medical School Liege, Belgium University of Medicine and Dentistry of New Jersey Anna Glasier, M.D., Ph.D. New Brunswick, NJ, U.S.A. Consultant and Director Family Planning and Well Woman Services Linda Cardozo, M.D. Lothian Primary Care Professor of Urogynecology Edinburgh, United Kingdom Department of Obstetrics and Gynecology King’s College Hospital Elina Hemminki, M.D., Ph.D. London, United Kingdom Research Professor National Research and Development Centre for Sir Richard Doll Welfare and Health, STAKES Emeritus Professor ofMedicine Helsinki, Finland Clinical Trial Service Unit and Epidemiology Study Unit (CTSU) Myra S. Hunter, Ph.D. University of Oxford Department of Psychology Harkness Laboratory St. Thomas Hospital Oxford, United Kingdom London, United Kingdom Timothy M. M. Farley, Ph.D. Won-Whe Kim, M.D. Epidemiological Research Professor Special Programme of Research Department of Obstetrics and Gynecology Development and Research Training in Human Pusan National University School ofMedicine Reproduction Pusan, Korea Department of Reproductive Health and Research World Health Organization Britt-Marie Landgren, M.D., Ph.D. Geneva, Switzerland Professor Department of Obstetrics and Gynecology Marcha Flint, Ph.D. Huddinge University Hospital Department ofAnthropology Stockholm, Sweden Montclair State University Upper Montclair, NJ, U.S.A. v Lenore Manderson, Ph.D. Henri Rochefort, M.D., Ph.D. Director and Professor Hormones and Cancer Unit Key Centre for Women’s Health in Society INSERM U540 Faculty ofMedicine, Dentistry, and Montpellier, France Health Sciences The University ofMelbourne Giuseppe Rosano, M.D., Ph.D. Carlton, VIC, Australia Institute of Cardiology San Raffaele del Monte Tabor Hospital Olav Meirik, M.D., Ph.D. Rome, Italy Senior Research Associate Chilean Institute ofReproductive Medicine Raymond Rosen, Ph.D. Providencia, Santiago, Chile Robert Wood Johnson Medical School Department ofPsychiatry Daniel R. Mishell, Jr., M.D. Piscataway, NJ, U.S.A. Lyle G. McNeile Professor and Chairman Department of Obstetrics and Gynecology Karin Schenck-Gustafsson, M.D., Ph.D. Keck School ofMedicine Associate Professor, Department ofCardiology University of Southern California Director, Women’s Health Center Los Angeles, CA, U.S.A. Karolinska Institute Stockholm, Sweden Bert O’Malley, M.D. Department ofMolecular and Cellular Biology Peter Schmidt, M.D. Baylor College ofMedicine National Institute ofMental Health Houston, TX, U.S.A. National Institutes of Health Bethesda, MD, U.S.A. Bent Ottesen, M.D. Department of Obstetrics and Gynecology Ethel Siris, M.D. Hvidovre Hospital Madeline C. Stabile Professor of University of Copenhagen Clinical Medicine Copenhagen, Denmark Director ofthe Toni Stabile Osteoporosis Center Columbia University David Purdie, M.D. New York, NY, U.S.A. Centre for Metabolic Bone Disease Hull Royal Infirmary Sven O. Skouby, M.D. Hull, United Kingdom Professor, D.M.Sc. Department of Obstetrics and Gynecology Lawrence G. Raisz, M.D. Frederiksberg University Hospital Program Director Copenhagen, Denmark General Clinical Research Center University ofConnecticut Health Center Leon Speroff, M.D. Farmington, CT, U.S.A. Department of Obstetrics and Gynecology Oregon Health Sciences University Portland, OR, U.S.A. VI John C. Stevenson, M.B.B.S. Cornelia Van Duijn, M.D. Endocrinology and Metabolic Medicine Department ofEpidemiology and Biostatistics Mint Wing, St. Mary’s Hospital Erasmus University Medical School London, United Kingdom Rotterdam, The Netherlands David W. Sturdee, M.D. Nancy F. Woods, Ph.D., R.N. Consultant, Obstetrician and Gynecologist Dean, School of Nursing Department of Obstetrics and Gynecology University ofWashington Solihull Hospital Seattle, WA, U.S.A. Senior Clinical Lecturer Birmingham University West Midlands, United Kingdom WITH APPRECIATION FOR THE EXPERTISE OF THE FOLLOWING, WHO GRACIOUSLY REVIEWED AND COMMENTED ON THE PRELIMINARY COMPOSITE MANUSCRIPT: Takeshi Aso, M.D., Ph.D. Peter Kenemans, M.D., Ph.D. Professor and Chairman Professor and Chairman Comprehensive Reproductive Medicine Department of Obstetrics and Gynecology Department of Obstetrics and Gynecology Director Menopause Project “Ageing Women” Graduate School, Tokyo Medical and Vrije University Medical Centre Dental University Amsterdam, The Netherlands Tokyo, Japan Luella Klein, M.D. Giuseppe Benagiano, M.D. Charles Howard Candler Professor Professor and Past Director Department of Gynecology and Obstetrics National Institute ofHealth Emory University School of Medicine Rome, Italy Director, Maternal and Infant Care Project Grady Memorial Hospital Henry Burger, M.D., Ph.D. Atlanta, GA, U.S.A. Professor, Prince Henry’s Institute of Medical Research Rogerio A. Lobo, M.D. Monash Medical Center Willard C. Rappleye Professor of Obstetrics and Clayton, VIC, Australia Gynecology Chairman ofthe Department Desmond Julian, M.D. College ofPhysicians and Surgeons of Emeritus Professor, Department of Cardiology Columbia University Medical School University ofNewcastle upon Tyne Director, Sloane Hospital for Women London, United Kingdom Columbia-Presbyterian Medical Center New York, NY, U.S.A. VII Michael Mendelsohn, M.D. Isaac Schiff, M.D. Director, Molecular Cardiac Research Institute Joe Vincent Meigs Professor of Gynecology, New England Medical Center Harvard Medical School Professor of Medicine and Physiology Chief ofVincent Memorial, Obstetrics and Tufts University School of Medicine Gynecology Service Boston, MA, U.S.A. The Women’s Care Division of the Massachusetts General Hospital Henri Rozenbaum, M.D. Boston, MA, U.S.A. President French Association for the Study of Piero Sismondi, M.D., Ph.D. Menopause (AFEM) Professor ofGynecologic Oncology Federation of European Menopause Director, Department of Obstetrics and Societies (FEMS) Gynecology Paris, France Umberto I Mauriziano Hospital Institute for Cancer Research and Treatment Goran Samsioe, M.D. (I.R.C.C.) Professor Candiolo (Turin), Italy Department of Obstetrics and Gynecology Lund University Hospital Wulf H. Utian, M.D. President-Elect Chairman European Menopause and Andropause Society The North American Menopause Society Lund, Sweden Mayfield Heights, OH, U.S.A. Nelson Watts, M.D. Director, University of Cincinnati Osteoporosis Center Cincinnati, OH, U.S.A. SPECIAL ACKNOWLEDGMENT Suzanne S. Hurd, Ph.D. Ruth Johnsson Hegyeli, M.D. Scientific Director Associate Director for International Programs Medical Communications Resources, Inc. National Heart, Lung, and Blood Institute Gaithersburg, MD, U.S.A. National Institutes of Health Bethesda, MD, U.S.A. VIII
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