International Journal of Radiation Oncology, Biology, Physics 1993: Vol 26 Table of Contents

10 Pages·1993·2.6 MB·English

Int. J. Radiation Oncology Biol. Phys., Vol. 26, pp. II-X VIII 0360-3016/93 $6.00 + .00
Printed in the U.S.A. All rights reserved. Copyright © 1993 Pergamon Press Ltd.
INTERNATIONAL JOURNAL OF
RADIATION ONCOLOGY
BIOLOGY: PHYSICS
VOLUME 26, NUMBER | APRIL 30, 1993
TABLE OF CONTENTS
Editor’s Note
P. Rubin l
@ CLINICAL ORIGINAL CONTRIBUTIONS
Evaluation of the Dose for Postoperative Radiation Therapy of Head and Neck Cancer: First Report of a Pro-
spective Randomized Trial
L. J. Peters, H. Goepfert, K. K. Ang, R. M. Byers, M. H. Maor, O. Guillamondegui, W. H. Morrison, R. S.
Weber, A. S. Garden, R. A. Frankenthaler, M. J. Oswald and B. W. Brown 3
A Prospective Trial of Accelerated Radiotherapy in the Postoperative Treatment of High-Risk Squamous Cell
Carcinoma of the Head and Neck
A. Trotti, D. Klotch, J. Endicott, M. Ridley and H. Greenberg 13
Effect of Delay in Radiation in the Combined Modality Treatment of Breast Cancer
T. A. Buchholz, M. M. Austin-Seymour, R. E. Moe, G. K. Ellis, R. B. Livingston, J. G. Pelton and T. W. Griffin 23
Primary Chemotherapy and Radiosurgical Breast-conserving Treatment for Patients with Locally Advanced
Operable Breast Cancers
G. Calais, P. Descamps, S. Chapet, V. Turgeon, A. Reynaud-Bougnoux, E. Lemarié, A. Fignon, G. Body, P.
Bougnoux, J. Lansac and O. Le Floch 37
Radiation-induced Brachial Plexopathy: Neurological Follow-up in 161 Recurrence-free Breast Cancer Patients
N. K. Olsen, P. Pfeiffer, L. Johannsen, H. Schrader and C. Rose 43
Brachytherapy for Stage I & II Oral Tongue Cancer: An Analysis of Past Cases Focusing on Control and
Complications
H. Shibuya, M. Hoshina, M. Takeda, S. Matsumoto, S. Suzuki and N. Okada
Radiotherapy is Successful Treatment for Orbital Lymphoma
M. C. Smitt and S. S. Donaldson
Management of Inverted Papilloma of the Nasal Cavity and Paranasal Sinuses: Importance of Radiation Therapy
E. B. Hug, C. C. Wang, W. W. Montgomery and M. L. Goodman
Radiotherapy Alone for Squamous Cell Carcinoma of the Nasal Vestibule: Management of the Primary Site and
Regional Lymphatics
W. M. McCollough, N. P. Mendenhall, J. T. Parsons, W. M. Mendenhall, S. P. Stringer, N. J. Cassisi and
R. R. Million
@ BIOLOGY ORIGINAL CONTRIBUTIONS
Alterations in Growth Phenotype and Radiosensitivity After Fractionated Irradiation of Breast Carcinoma Cells
from a Single Patient
D. E. Wazer, M. Joyce, L. Jung and V. Band
Effect of Conjoint Administration of Tamoxifen and High-Dose Radiation on the Development of Mammary
Carcinoma
D. A. Kantorowitz, H. J. Thompson and P. Furmanski
Nicotinamide Exerts Different Acute Effects on Microcirculatory Function and Tissue Oxygenation in Rat Tumors
D. K. Kelleher and P. W. Vaupel
Therapeutic Effect of Infused Fluosol-DA/Carbogen with Ephedrine, Flunarizine, or Nitroprusside
B. A. Teicher, S. A. Holden, D. Northey, M. W. Dewhirst and T. S. Herman
@ HYPERTHERMIA ORIGINAL CONTRIBUTION
Deep Regional Hyperthermia: Comparison Between the Annular Phased Array and the Sigma-60 Applicator in
the Same Patients
H. J. Feldmann, M. Molls, S. Kriimpelmann, M. Stuschke and H. Sack
Ill
@ BRIEF COMMUNICATIONS
Bronchoalveolar Lavage Fluid Findings Following Radiotherapy for Non-small Cell Lung Cancer
P. Maasilta, M. Hallman, E. Taskinen, L. Kivisaari and K. Mattson 117
Anaplastic Carcinoma of the Thyroid Gland Treated by Radiation Therapy
P. C. Levendag, P. M. Z. R. De Porre and W. L. J. van Putten 125
Good Performance Status of Long-term Disease-free Survivors of Intracranial Gliomas
L. Kleinberg, K. Wallner and M. G. Malkin 129
Angiosarcoma of the Breast Following Lumpectomy, Axillary Lymph Node Dissection, and Radiotherapy for
Primary Breast Cancer: Three Case Reports and a Review of the Literature
A. Wijnmaalen, B. van Ooijen, B. N. van Geel, S. C. Henzen-Logmans and A. D. Treurniet-Donker 135
Malignant Spinal Cord Compression: A Prospective Evaluation
S. Turner, B. Marosszeky, I. Timms and J. Boyages 141
@ TECHNICAL INNOVATIONS AND NOTES
3-Dimensional Optimization of Multiple Arcs for Stereotactic Radiosurgery
K. J. Weeks, L. Marks, S. K. Ray, D. P. Spencer, D. A. Turner and A. H. Friedman 147
The Investigation and Rectification of Field Placement Errors in the Delivery of Complex Head and Neck Fields
P. B. Dunscombe, K. Fox, S. Loose and K. Leszczynski 155
A CT-based Evaluation Method for Permanent Implants: Application to Prostate
J. N. Roy, K. E. Wallner, P. J. Harrington, C. C. Ling and L. L. Anderson 163
Dose, Volume, and Tumor-control Predictions in Radiotherapy
D. J. Brenner 171
@ EDITORIALS
Postoperative Irradiation in Head and Neck Cancer
J. S. Cooper
Sequencing Adjuvant Chemotherapy and Radiotherapy in Breast Cancer Patients
J. R. Harris and A. Recht
Inverted Papilloma of the Nasal Cavity or Paranasal Sinuses: A Malignant Benign Tumor
R. R. Million
@ CORRESPONDENCE
In Response to Drs. Harris and Recht: Optimal Sequencing of Chemotherapy and Radiation
T. A. Buchholz
In Response to Dr. Million: Radiation Therapy for Inverted Papilloma
C. C. Wang
@ MEETINGS
VOLUME 26, NUMBER 2 MAY 20, 1993
TABLE OF CONTENTS
Editor’s Note
P. Rubin
@ CLINICAL ORIGINAL CONTRIBUTIONS
Twenty Years Follow-up of Patients with Inoperable Cancer of the Prostate (Stage C) Treated by Radiotherapy:
Report of a National Cooperative Study
J. A. del Regato, with the collaboration of A. H. Trailins and D. D. Pittman
Carcinoma of the Prostate: Results of Radical Radiotherapy (1970-1985)
W. Duncan, P. Warde, C. N. Catton, A. J. Munro, R. Lakier, T. Gadalla and M. K. Gospodarowicz
Effect of Split-course Radiotherapy on Survival and Local Control in Advanced Localized Prostatic Carcinoma
M. Kajanti, L. R. Holsti, P. Holsti and K. M6ykkynen
IV
Adverse Effect of Transurethral Resection on Disease-free Survival in Locally Advanced Prostatic Cancer Treated
with Irradiation
C. Landmann, R. Hunig and G. Rutishauser 217
Exclusive Radiation Therapy in Endometrial Carcinoma
P. Rouanet, J. B. Dubois, S. Gely and H. Pourquier 223
A Retrospective Study of the Effects of Pelvic Irradiation for Carcinoma of the Cervix on Gastrointestinal
Function
E. Yeoh, M. Horowitz, A. Russo, T. Muecke, A. Ahmad, T. Robb and B. Chatterton 229
Influence of Location and Extent of Surgical Resection on Survival of Patients with Glioblastoma Multiforme:
Results of Three Consecutive Radiation Therapy Oncology Group (RTOG) Clinical Trials
J. R. Simpson, J. Horton, C. Scott, W. J. Curran, P. Rubin, J. Fischbach, S. Isaacson, M. Rotman, S. O. Asbell,
J. S. Nelson, A. S. Weinstein and D. F. Nelson 239
The Treatment of 783 Keloid Scars by Iridium 192 Interstitial Irradiation After Surgical Excision
P. Escarment, S. Zimmerman, A. Amar, J.-L. Ratoanina, A. Moris, H. Azaloux, H. Francois, O. Gosserez,
M. Michel and R. G’Baguidi 245
@ HYPERTHERMIA ORIGINAL CONTRIBUTION
Feasibility and Toxicity of Transrectal Ultrasound Hyperthermia in the Treatment of Locally Advanced Ade-
nocarcinoma of the Prostate
H. Fosmire, K. Hynynen, G. W. Drach, B. Stea, P. Swift and J. R. Cassady
@ PHYSICS ORIGINAL CONTRIBUTION
Commissioning and Quality Assurance of Treatment Planning Computers
J. Van Dyk, R. B. Barnett, J. E. Cygler and P. C. Shragge
@ BIOLOGY ORIGINAL CONTRIBUTIONS
Marrow Toxicity of Fractionated vs. Single Dose Total Body Irradiation is Identical in a Canine Model
R. Storb, R. F. Raff, T. Graham, F. R. Appelbaum, H. Joachim Deeg, F. G. Schuening, H. Shulman
and M. Pepe
Rapid Vascular Escape of Arterially Injected 16alpha-Radioiodo,17beta-Estradiol
A. Scharl and J. A. Holt
@ BRIEF COMMUNICATIONS
Charged Particle Irradiation of Sacral Chordomas
R. Schoenthaler, J. R. Castro, P. L. Petti, K. Baken-Brown and T. L. Phillips
Radiation Therapy for Giant Cell Tumor of Bone
C. J. Bennett, Jr., R. B. Marcus, Jr., R. R. Million and W. F. Enneking
Static and Dynamic Vascular Impact of Large Artery Irradiation
M. J. Goodman, S. G. Lalka and S. Reddy
@ TECHNICAL INNOVATIONS AND NOTES
Development of a Second-generation Fiber-optic On-line Image Verification System
J. W. Wong, A. Y. Cheng, W. R. Binns, J. W. Epstein, J. Klarmann and C. A. Perez
Objective Evaluation of 3-D Radiation Treatment Plans: A Decision-Analytic Tool Incorporating Treatment
Preferences of Radiation Oncologists
N. L. Jain, M. G. Kahn, R. E. Drzymala, B. E. Emami and J. A. Purdy
Gain in Target Dose from Using Computer Controlled Radiation Therapy (CCRT) in the Treatment of Non-
small Cell Lung Cancer
C. S. Ha, P. K. Kijewski and M. P. Langer
Rectal Thermoluminescent Dosimeter Measurements Using the MicroSelectron High Dose Rate Afterloader in
Postoperative Intravaginal Radiation Cases
N. Kessaris and D. Nori
A Template for Rigid Stereotaxic Afterloading Brachytherapy of the Brain
L. Beach, A. B. Young and R. A. Patchell
@ ONCOLOGY INTELLIGENCE
Why Shorter Half-times of Repair Lead to Greater Damage in Pulsed Brachytherapy
J. F. Fowler
Concerning the Inferior Portion of the Spinal Radiotherapy Field for Malignancies that Disseminate Via the
Cerebrospinal Fluid
E. C. Halperin 357
@ EDITORIALS
Incomparable Report of Clinical Trial for Locally Advanced Carcinoma of the Prostate
J. D. Cox 363
Conventional External Beam Radiation Therapy for Prostatic Cancer: Where Do We Go from Here?
M. J. Zelefsky, S. A. Leibel and Z. Fuks 365
Prostate Cancer: Hot, But Hot Enough?
J. R. Oleson 369
Comments on: Commissioning and Quality Assurance of Treatment Planning Computers
D. L. McShan 371
@ CORRESPONDENCE
Response to Oleson
H. Fosmire and K. Hynynen 373
Response to Zelefsky et al.
W. Duncan 373
@ MEETINGS
VOLUME 26, NUMBER 3 JUNE 15, 1993
TABLE OF CONTENTS
Editor’s Note
P. Rubin
@ CLINICAL ORIGINAL CONTRIBUTIONS
Postorchiectomy Radiotherapy for Stages I and II Testicular Seminoma
M. A. Dosmann and G. K. Zagars
Breast Conservation Therapy for Intraductal Carcinoma of the Breast
R. R. Kuske, J. M. Bean, D. M. Garcia, C. A. Perez, D. Andriole, G. Philpott and B. Fineberg
Combined Chemotherapy-Radiotherapy in Advanced Hodgkin’s Disease: Results of a Prospective Clinical Trial
with 70 Stage IIIB-IV Patients
C. Fermé, E. Lepage, P. Brice, M.-F. D’Agay, J.-P. Fermand, S. Castaigne, J. Frija, C.M iot, M. Marty and
C. Gisselbrecht 397
Clinical Study of Radioprotective Effects of Amifostine (YM-08310, WR-2721) on Long-term Outcome for
Patients with Cervical Cancer
N. Mitsuhashi, I. Takahashi, M. Takahashi, K. Hayakawa and H. Niibe
A Double-blind, Randomized, Prospective Trial to Evaluate Topical Vitamin C Solution for the Prevention of
Radiation Dermatitis
E. C. Halperin, L. Gaspar, S. George, D. Darr and S. Pinnell for the CNS Cancer Consortium
@ BIOLOGY ORIGINAL CONTRIBUTIONS
Interleukin-1 Modulatory Effect on the Action of Chemotherapeutic Drugs and Localized Irradiation of the Lip,
Duodenum, and Tumor
M. S. Zaghloul, M. J. Dorie and R. F. Kallman
Failure of Hyperfractionated Radiotherapy to Reduce Bone Growth Arrest in Rats
K. Wechsler-Jentzsch, H. Hiiepfel, W. Schmidt, E. Wandl and B. Kahn
(Contents continued on page 00)
(Contents continued)
Radiosensitization by a New Potent Nucleoside Analog: 1-(1',3',4'-Trihydroxy-2'-Butoxy)Methyl-2-Nitroimid-
azole(RP-343)
C. Murayama, A. Suzuki, C. Sato, Y. Tanabe, T. Shoji, Y. Miyata, A. Nishio, T. Suzuki, M. Sakaguchi and
T. Mori
VI
Combination of Aziridinylbenzoquinone and Cis-Platinum with Radiation Therapy in the 9L Rat Brain Tumor
Model
B. F. Kimler, C. Liu, R. G. Evans and R. A. Morantz 445
@ HYPERTHERMIA ORIGINAL CONTRIBUTION
Prediction of Treatment Temperatures in Clinical Hyperthermia of Locally Advanced Breast Carcinoma: The
Use of Contrast Enhanced Computed Tomography
H. Lyng, O. R. Monge, E. M. Sager and E. K. Rofstad 451
@ PHASE I/II CLINICAL TRIALS
A Phase I/II Study to Evaluate Accelerated Fractionation via Concomitant Boost for Squamous, Adeno, and
Large Cell Carcinoma of the Lung: Report of Radiation Therapy Oncology Group 84-07
R. W. Byhardt, T. F. Pajak, B. Emami, A. Herskovic, R. S. Doggett and L. A. Olsen 459
Report of Phase II Trial of Concurrent Chemoradiotherapy with Radical Thoracic Irradiation (60 Gy), Infu-
sional Fluorouracil, Bolus Cisplatin and Etoposide for Clinical Stage IIIB and Bulky IIIA Non-small Cell
Lung Cancer
C. J. Langer, W. J. Curran, Jr., S. M. Keller, R. Catalano, W. Fowler, K. Blankstein, S. Litwin, P. Bagchi,
S. Nash and R. Comis 469
@ BRIEF COMMUNICATIONS
Radiation Induced Lumbosacral Plexopathy in Gynecologic Tumors: Clinical Findings and Dosimetric Analysis
A. Georgiou, P. W. Grigsby and C. A. Perez 479
Patterns of Failure in Grossly Resected Pancreatic Ductal Adenocarcinoma Treated with Adjuvant Irradiation
+ 5 Fluorouracil
M. L. Foo, L. L. Gunderson, D. M. Nagorney, D. C. McLIrath, J. A. van Heerden, J. S. Robinow, L. K. Kvols,
G. R. Garton, J. A. Martenson and S. S. Cha 483
Gorham’s Massive Osteolysis: The Role of Radiation Therapy and a Review of the Literature
S. F. Dunbar, A. Rosenberg, H. Mankin, D. Rosenthal and H. D. Suit 491
@ TECHNICAL INNOVATIONS AND NOTES
Optimized Low Dose Rate Pellet Configurations for Intravaginal Brachytherapy
R. S. Sloboda, R. G. Pearcey and S. J. Gillan
Positional Stability of Sources During Low-Dose-Rate Brachytherapy for Cervical Carcinoma
B. W. Corn, J. M. Galvin, E. M. Soffen, G. Henze and F. Schwaibold
Concept of Dose Nonuniformity in Interstitial Brachytherapy
C. B. Saw, N. Suntharalingam and A. Wu
The Reliability of Optimization Under Dose-Volume Limits
M. Langer, R. Brown, P. Kijewski and C. Ha
The Effect of Advanced Age on the Efficacy of Radiation Therapy for Early Breast Cancer, Local Prostate
Cancer and Grade III-IV Gliomas
R. E. Peschel, L. Wilson, B. Haffty, D. Papadopoulos, K. Rosenzweig and M. Feltes
@ EDITORIALS
Stage I, II Seminoma—Then and Now
G. M. Thomas
Breast Conservation Therapy for Ductal Carcinoma Jn Situ
B. L. Fowble
@ CORRESPONDENCE
Response to Editorial by Dr. Gillian M. Thomas
G. K. Zagars
Current Issues in the Management of Intraductal Breast Cancer: Response to Dr. Fowble’s Editorial
R. R. Kuske
@ RAPID COMMUNICATION
Late Rectal Bleeding Following Combined X-Ray and Proton High Dose Irradiation for Patients with Stages
T3-T4 Prostate Carcinoma
V. A. Benk, J. A. Adams, W. U. Shipley, M. M. Urie, P. L.M cManus, J. T. Efird, C. G. Willett and M. Goitein
Vil
@ MEETINGS
@ ERRATUM 563
VOLUME 26, NUMBER 4 JULY 15, 1993
TABLE OF CONTENTS
Editor’s Note
P. Rubin 565
@ 1992 ASTRO GOLD MEDAL ADDRESS
Quest for Excellence: The Ultimate Goal of the Radiation Oncologist: Astro Gold Medal Address, 1992
C. A. Perez 567
@ CLINICAL ORIGINAL CONTRIBUTIONS
Technical and Tumor-Related Factors Affecting Outcome of Definitive Irradiation for Localized Carcinoma of
the Prostate
C. A. Perez, H. K. Lee, A. Georgiou, M. D. Logsdon, P. P. Lai and M. A. Lockett 581
Regional Nodal Management and Patterns of Failure Following Conservative Surgery and Radiation. Therapy
for Stage I and II Breast Cancer
K. J. Halverson, M. E. Taylor, C. A. Perez, D. M. Garcia, R. Myerson, G. Philpott, J. Levy, J. R. Simpson,
G. Tucker and C. Rush
Influence of Dose-rate and Dose Per Fraction on Clinical Outcome of Breast Cancer Treated by External Beam
Irradiation Plus Iridium-192 Implants: Analysis of 289 Cases
S. M. Deore, R. Sarin, K. A. Dinshaw and S. K. Shrivastava
Survival in Patients with Paraaortic Lymph Node Metastases from Endometrial Adenocarcinoma Clinically
Limited to the Uterus
M. L. Hicks, M. S. Piver, J. L. Puretz, R. E. Hempling, T. R. Baker, M. Mcauley and D. L. Walsh
High Intensity 125-Iodine ('*5I) Plaque Treatment of Uveal Melanoma
J. M. Quivey, D. H. Char, T. L. Phillips, K. A. Weaver, J. R. Castro and S. M. Kroll
Treatment of Choroidal Melanoma with I-125 Plaque
J. Fontanesi, D. Meyer, S. Xu and D. Tai
Cataractogenesis After Cobalt-60 Eye Plaque Radiotherapy
M. Kleineidam, J. J. Augsburger, C. Hernandez, P. Glennon and L. W. Brady
@ BIOLOGY ORIGINAL CONTRIBUTIONS
Oxygen Tension Distributions are Sufficient to Explain the Local Response of Human Breast Tumors Treated
with Radiation Alone
P. Okunieff, M. Hoeckel, E. P. Dunphy, K. Schlenger, C. Knoop and P. Vaupel
Halogenated Pyrimidine Sensitization of Low Dose Rate Irradiation in Human Malignant Glioma
P. W. McLaughlin, W. R. Mancini, P. L. Stetson, H. S. Greenberg, N. Nguyen, H. Seabury, D. B. Heidorn and
T. S. Lawrence
Late Effects of Radiation on the Lumbar Spinal Cord of Guinea Pigs: Re-treatment Tolerance
K. A. Mason, H. R. Withers and C.-S. Chiang
@ PHASE I/II CLINICAL TRIALS
Lack of Complications in Long-term Survivors After Treatment with Fluosol® and Oxygen as an Adjuvant to
Radiation Therapy for High-grade Brain Tumors
R. G. Evans, B. F. Kimler, R. A. Morantz and S. Batnitzky
Phase I/II Trial of Accelerated Fractionation in Brain Metastases RTOG 85-28
W. T. Sause, C. Scott, R. Krisch, M. Rotman, P. K. Sneed, N. Janjan, L. Davis, W. Curran, K. N. Choi,
H. Selim, M. Mohiuddin and P. Grigsby
@ THERAPEUTIC ONCOLOGIC IMAGING
The Utility of SPECT Lung Perfusion Scans in Minimizing and Assessing the Physiologic Consequences of
Thoracic Irradiation
L. B. Marks, D. P. Spencer, G. C. Bentel, S. K. Ray, G. W. Sherouse, M. R. Sontag, R. E. Coleman,
R. J. Jaszczak, T. G. Turkington, V. Tapson and L. R. Prosnitz
Vill
Radiologic Determination of the Caudal Border of the Spinal Field in Cranial Spinal Irradiation
S. F. Dunbar, P. D. Barnes and N. J. Tarbell
@ BRIEF COMMUNICATION
Breast Conserving Surgery and Irradiation: The Importance of Demarcating the Excision Cavity with
Surgical Clips
J. Bedwinek
@ TECHNICAL INNOVATIONS AND NOTES
A Large Screen Digitizer System for Radiation Therapy Treatment Planning
D. L. McShan, G. Matrone, B. A. Fraass and A. S. Lichter
Three-Dimensional Conformal Radiation Therapy May Improve the Therapeutic Ratio of High Dose Radiation
Therapy for Lung Cancer
J. G. Armstrong, C. Burman, S. Leibel, D. Fontenla, G. Kutcher, M. Zelefsky and Z. Fuks
A Phantom for Beam Positioning and Visualization
M. K. Woo and S. Wong
The Transit Dose Component of High Dose Rate Brachytherapy: Direct Measurements and Clinical Implications
K. T. Bastin, M. B. Podgorsak and B. R. Thomadsen
@ LETTERS FROM ABROAD
Simple Radiotherapy Techniques
C. Papavasiliou
@ EDITORIALS
The Challenge for Conformal Therapy for Prostate Cancer
C. J. Beard, I. D. Kaplan and C. N. Coleman
Regional Lymph Node Management in Conservation Treatment of Early Stage Invasive Breast Carcinoma
L. J. Solin
Insights in Para-aortic Radiation Therapy for Endometrial Carcinoma
M. Rotman, H. Aziz and R. Boronow
Radiation-induced Cataracts: Simple But Difficult to Quantify
R. H. Sagerman
Retreatment Tolerance of the Spinal Cord
A. J. van der Kogel
@ CORRESPONDENCE
Slow Progress in the Treatment of Para-aortic Lymph Node Metastasis from Clinical Stage I Endo-
metrial Adenocarcinoma
M. S. Piver
@ RAPID COMMUNICATION
Effect of Subcutaneous Recombinant Human Erythropoietin in Cancer Patients Receiving Radiotherapy: Prelim-
inary Results of a Randomized, Open-Labeled, Phase II Trial
S. Vijayakumar, M. Roach III, W. Wara, S. K. Chan, C. Ewing, S. Rubin, H. Sutton, H. Halpern, A. Awan,
A. Houghton, C. Quiet and R. Weichselbaum
@ AWARDS
1992 ASTRO Gold Medal Recipients: Drs. E. D. Montague and C. A. Perez
@ MEETINGS
VOLUME 26, NUMBER 5 AUGUST 1, 1993
TABLE OF CONTENTS
This Issue is Dedicated to the Women of Radiation Oncology Who have Advanced
the Science and Bettered the Art of Cancer Patient Care
Editor’s Note
P. Rubin
@ SPECIAL FEATURE: 1992 ASTRO PRESIDENTIAL ADDRESS
Lessons from Our Children
S. S. Donaldson 739
@ CLINICAL ORIGINAL CONTRIBUTIONS
Pharyngeal Wall Carcinoma Treated with Radiotherapy: Impact of Treatment Technique and Fractionation
D. A. Fein, W. M. Mendenhall, J. T. Parsons, S. P. Stringer, N. J. Cassisi and R. R. Million 751
The Management of the Clinically Positive Neck as Part of a Larynx Preservation Approach
J. Armstrong, D. Pfister, E. Strong, R. Heimann, D. Kraus, A. Polishook, M. Zelefsky, G. Bosl, J. Shah,
R. Spiro and L. Harrison 759
Prognostic Factors for Local Control and Survival in T1 Squamous Cell Carcinoma of the Glottis
M. S. Rudoltz, A.B enammar and M. Mohiuddin 767
Retrospective Analysis of Patients with Nasopharyngeal Carcinoma Treated During 1976-1985: Survival After
Local Recurrence
A. W. M. Lee, S. C. K. Law, W. Foo, Y. F. Poon, F. K. Cheung, D. K. K. Chan, S. Y. Tung, M. Thaw
and J. H. C. Ho 773
Re-Irradiation of Laryngeal Carcinoma—Techniques and Results
C. C. Wang and J. McIntyre 783
Computed Tomography Evaluation of Neck Node Metastases from Nasopharyngeal Carcinoma
J.S. T. Sham, Y. K. Cheung, D. Choy, F. L. Chan and L. Leong
@ PHASE I/II CLINICAL TRIALS
In Vivo Measurement of the Potential Doubling Time by Flowcytometry in Oropharyngeal Cancer Treated by
Conventional Radiotherapy
J. Bourhis, G. Wilson, P. Wibault, J. Bosq, N. Chavaudra, F. Janot, B. Luboinski, F. Eschwege and E. P. Malaise
Cisplatin, Hyperthermia, and Radiation (Trimodal Therapy) in Patients with Locally Advanced Head and Neck
Tumors: A Phase I-II Study
M. Amichetti, C. Graiff, G. Fellin, G. Pani, A. Bolner, S. Maluta and R. Valdagni
Combined Radiotherapy and Chemotherapy in the Management of Local-Regionally Advanced Vulvar Cancer
W.-J. Koh, H. J. Wallace III, B. E. Greer, J. Cain, K. J. Stelzer, K. J. Russell, H. K. Tamimi, D. C. Figge,
A. H. Russell and T. W. Griffin
@ BIOLOGY ORIGINAL CONTRIBUTIONS
Mathematical Models of Marrow Cell Kinetics: Differential Effects of Protracted Irradiations on Stromal and
Stem Cells in Mice
T. D. Jones, M. D. Morris and R. W. Young
Expression of p210 BCR/ABL Increases Hematopoietic Progenitor Cell Radiosensitivity
M. A. Santucci, P. Anklesaria, P. Laneuville, I. J. Das, M. A. Sakakeeny, T. J. FitzGerald and J. S. Greenberger
The Differential Induction of Collateral Resistance to 62.5 MeV (p—Be* ) Neutrons and 4 MeV Photons by
Exposure to Cis-Platinum
R. A. Britten, H. M. Warenius, J. R. W. Masters and J. H. Peacock
@ BRIEF COMMUNICATIONS
Use of Recombinant Granulocyte-Colony Stimulating Factor to Treat Neutropenia Occurring During Cranio-
spinal Irradiation
M. P. Mac Manus, J. Clarke, D.M cCormick and W. P. Abram
The Management of Desmoid Tumors
J. C. Acker, E. H. Bossen and E. C. Halperin
Intraoperative Radiotherapy In Locally Advanced Recurrent Colorectal Cancer
O. Abuchaibe, F. A. Calvo, I. Azinovic, J. Aristu, F. Pardo and J. Alvarez-Cienfuegos
@ TECHNICAL INNOVATIONS AND NOTES
Objective Decision-Making Following a Portal Film: The Results of a Pilot Study
J. W. Denham, M. J. Dally, K. Hunter, J. Wheat, P. P. Fahey and C. S. Hamilton
A New Technique for Positioning Tangential Fields
J. M. Galvin, W. Powlis, B. Fowble and R. L. Goodman
Tolerances in Setup and Dosimetric Errors in the Radiation Treatment of Breast Cancer
I. J. Das, C.-W. Cheng, H. Fosmire, K. R. Kase and T. J. Fitzgerald 883
Analysis of Temperature Distributions of Interstitial Hyperthermia Using a Hot Water System
G. Stuecklschweiger, K. S. Arian-Schad, D. S. Kapp, L. Handl-Zeller and A. G. Hackl 891
Solid Phantom Material for the Dosimetry of Iodine-125 Seed Ophthalmic Plaques
K.-P. Hermann, W. Alberti, P. Tabor, B. Pothmann, S. Divoux and D. Harder 897
@ EDITORIALS
Decision Making for Re-Irradiation of Nasopharyngeal Carcinoma
C. C. Wang 903
The Use of G-CSF During Craniospinal Irradiation
L. B. Marks and E. C. Halperin 905
@ CORRESPONDENCE
Response to Editorial by Dr. Wang
A. W. M. Lee 907
Response to Drs. Marks and Halperin
M. P. Mac Manus, J. Clarke, D. McCormick and W. P. Abram 907
@ MEETINGS
@ LIST OF CONTENTS, AUTHOR INDEX, AND SUBJECT INDEX FOR
VOLUME 26, 1993