Influenza and Respiratory Care

104 Pages·2017·1.87 MB·English

by  Mieczyslaw Pokorski (eds.)

Advances in Experimental Medicine and Biology 968
Neuroscience and Respiration
Mieczyslaw Pokorski Editor
Infl uenza and
Respiratory
Care
Advances in Experimental Medicine
and Biology
Neuroscience and Respiration
Volume 968
Editorial Board
Irun R. Cohen, The Weizmann Institute of Science, Rehovot, Israel
N.S.AbelLajtha,KlineInstituteforPsychiatricResearch,Orangeburg,NY,USA
John D. Lambris, University of Pennsylvania, Philadelphia, PA, USA
Rodolfo Paoletti, University of Milan, Milan, Italy
Subseries Editor
Mieczyslaw Pokorski
Moreinformationaboutthisseriesathttp://www.springer.com/series/13457
Mieczyslaw Pokorski
Editor
Influenza and
Respiratory Care
Editor
MieczyslawPokorski
OpoleMedicalSchool
Opole,Poland
ISSN0065-2598 ISSN2214-8019 (electronic)
AdvancesinExperimentalMedicineandBiology
ISBN978-3-319-51711-7 ISBN978-3-319-51712-4 (eBook)
DOI10.1007/978-3-319-51712-4
LibraryofCongressControlNumber:2017942751
#SpringerInternationalPublishingAG2017
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Preface
The book series Neuroscience and Respiration presents contributions by
expert researchers and clinicians in the multidisciplinary areas of medical
research and clinical practice. Particular attention is foused on pulmonary
disorders asthe respiratorytract is upfrontat the first line of defense of the
organism against pathogens and environmental or other sources of toxic or
diseasecausingeffects.Thearticlesprovidetimelyoverviewsofcontentious
issuesorrecentadvancesinthediagnosis,classification,andtreatmentofthe
entirerangeofdiseasesanddisorders,bothacuteandchronic.Thetextsare
thoughtasamergerofbasicandclinicalresearchdealingwithbiomedicine
atbothmolecularandfunctionallevels,andwiththeinteractiverelationship
betweenrespirationandotherneurobiologicalsystemssuchascardiovascu-
larfunction,immunogenicity,endocrinologyandhumoralregulation,orthe
mind-to-body connection. The authors focus on the modern diagnostic
techniques and the leading-edge therapeutic concepts, methodologies, and
innovative treatments. The action and pharmacology of existing drugs and
thedevelopmentandevaluationofnewagentsaretheheadyareaofresearch.
Practical, data-driven options to manage patients will be considered. New
research is presented regarding older drugs, performed from a modern
perspectiveorfromadifferentpharmacotherapeuticangle.Theintroduction
of new drugs and treatment approaches in both adults and children also is
discussed.
Body functions, including lung ventilation and its regulation, are ulti-
mately driven by the brain. However, neuropsychological aspects of
disordersarestillmostlyamatterofconjecture.Afterdecadesofmisunder-
standingandneglect,emotionshavebeenrediscoveredasapowerfulmodi-
fieroreventheprobablecauseofvarioussomaticdisorders.Today,thelink
between stress and health is undeniable. Scientists accept a powerful psy-
chological connection that can directly affect our quality of life and health
span. Psychologicalapproaches,bydecreasingstress, canplayamajor role
inthedevelopmentandtherapyofdiseases.
Neuromolecular and carcinogenetic aspects relating to gene polymor-
phism and epigenesis, involving both heritable changes in the nucleotide
sequenceandfunctionallyrelevantchangestothegenomethatdonotinvolve
achangeinthenucleotidesequence,leadingtodisorderswillalsobetackled.
Clinical advances stemming from molecular and biochemical research are
but possible if the research findings are translated into diagnostic tools,
v
vi Preface
therapeutic procedures, and education, effectively reaching physicians and
patients.Allthatcannotbeachievedwithoutamultidisciplinary,collabora-
tive, bench-to-bedside approach involving both researchers and clinicians.
The role of science in shaping medical knowledge and transforming it into
practicalcareisundeniable.
Concerningtherespiratorydisorders,theirsocietalandeconomicburden
has beenontheriseworldwideleading todisabilities andshorteningoflife
span.COPDalonecausesmorethanthreemilliondeathsgloballyeachyear.
Concerted efforts are required to improve this situation, and part of those
efforts are gaining insights into the underlying mechanisms of disease and
staying abreast with the latest developments in diagnosis and treatment
regimens. It is hoped that the articles published in this series will assume a
leading position as a source of information on interdisciplinary medical
research advancements, addressing the needs of medical professionals and
alliedhealthcareworkers,andbecomeasourceofreferenceandinspiration
forfutureresearchideas.
I would like to express my deep gratitude to Mr. Paul Roos, Ms. Tanja
Koppejan,andMs.CynthiaKroonenofSpringerSBMNLfortheirgenuine
interest in making this scientific endeavor come through and in the expert
managementoftheproductionofthisnovelbookseries.
MieczyslawPokorski
Contents
RapidInfluenzaDiagnosticTestsImproveSuitability
ofAntiviralTreatmentinHospitalizedChildren. . . . . . . . . . . . . . 1
AnetaNitsch-Osuch,ErnestKuchar,IzabelaGołe˛biak,
KrzysztofKanecki,PatrykTarka,andLidiaB.Brydak
Co-infectionwithInfluenzaVirusesandInfluenza-Like
VirusDuringthe2015/2016EpidemicSeason. . . . . . . . . . . . . . . . . 7
K.Szyman´ski,K.Cies´lak,D.Kowalczyk,andL.B.Brydak
InfluenzaandInfluenza-likeVirusesinChildrenintheEpidemic
Season2015/2016inPoland. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
K.Cies´lak,K.Szyman´ski,D.Kowalczyk,andL.B.Brydak
InfluenzaVaccinationCoverageAmongPolishPatients
withChronicDiseases. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
AnetaNitsch-Osuch,IzabellaGołe˛biak,DorotaWyszkowska,
RenataRosin´ska,LidiaKargul,Boz˙enaSzuba,PiotrTyszko,
andLidiaB.Brydak
CirculationofAntibodiesAgainstInfluenzaVirus
Hemagglutininsinthe2014/2015EpidemicSeasoninPoland. . . . . 35
D.Kowalczyk,K.Szyman´ski,K.Cies´lak,andL.B.Brydak
InfluenceofSocioeconomicandAnthropometricFactors
onRespiratoryFunctioninFemaleUniversityStudents. . . . . . . . . 41
D.Nowakowski,K.Klis´,M.Z˙urawiecka,A.Dubrowski,
andI.Wronka
RelationshipsBetweenQualityofLifeinthePsychological
Domain,AcceptanceofIllness,andHealthcareServices
inPatientswithAsthma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
Boz˙enaMroczek,KatarzynaParzuchowska,
MariaJasin´ska-Starczewska,TomaszGrodzki,andDonataKurpas
TheRelationshipBetweenBurnoutSyndromeAmong
theMedicalStaffandWorkConditionsinthePolish
HealthcareSystem. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
AlicjaGłe˛bocka
vii
viii Contents
AssociationofEstrogen-RelatedTraitswithAllergicRhinitis. . . . 71
KatarzynaKlis´andIwonaWronka
AlphaWaveletPowerasaBiomarkerofAntidepressant
TreatmentResponseinBipolarDepression. . . . . . . . . . . . . . . . . . 79
WojciechJernajczyk,PawełGosek,MiroslawLatka,
KlaudiaKozlowska,ŁukaszS´wie˛cicki,andBruceJ.West
Index. . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . 95
AdvsExp.Medicine,Biology-NeuroscienceandRespiration(2017)30:1–6
DOI10.1007/5584_2016_181
#SpringerInternationalPublishingSwitzerland2017
Publishedonline:18March2017
Rapid Influenza Diagnostic Tests Improve
Suitability of Antiviral Treatment
in Hospitalized Children
Aneta Nitsch-Osuch, Ernest Kuchar, Izabela Gołe˛biak,
Krzysztof Kanecki, Patryk Tarka, and Lidia B. Brydak
Abstract
Influenza may have a complicated course in young children. The aim of
the study was to analyze the suitability of influenza treatment among
childrenyoungerthan5yearshospitalizedduetoaninfluenza-likeillness.
Weconductedacomparisonofthetreatmentamongchildrenhospitalized
intwo consecutive years: 2015, when no rapid influenza diagnostic tests
(RIDT) were in use, and 2016, when RIDT were implemented into a
routine practice in the pediatric ward. In both seasons, nasopharyngeal
swabswerecollectedandexaminedwithrealtimeqRT-PCR.Inthe2015
season, influenza was diagnosed in 15/52 (28 %) children and none of
them received oseltamivir, while 14/15 (93 %) patients received
antibiotics.Inthe2016season,influenzawasdiagnosedin11/63(17%)
children, 7/11 (64 %) of them received oseltamivir and another 7/11
(64 %) received antibiotics. In four cases antibiotics overlapped
oseltamivir. These differences in the use of oseltamivir and antibiotics
werestatisticallysignificant(p<0.05).Weconcludethattheimplemen-
tation of RIDT improves the suitability of influenza treatment and
decreases the frequency of antibiotic therapy. RIDT should be available
inpediatricdepartmentstooptimizeinfluenzatreatment.
Keywords
Antibiotic Therapy (cid:129) Antiviral Treatment (cid:129) Children (cid:129) Hospitalization (cid:129)
Influenza-LikeIllness(cid:129)NeuraminidaseInhibitors
A.Nitsch-Osuch(*),I.Gołe˛biak,K.Kanecki,and
P.Tarka
DepartmentofSocialMedicineandPublicHealth,
MedicalUniversityofWarsaw,3OczkiStreet,02-007
Warsaw,Poland
e-mail:[email protected]
L.B.Brydak
E.Kuchar DepartmentofInfluenzaResearch,NationalInfluenza
DepartmentofPediatricswithClinicalAssessmentUnit, Center,NationalInstituteofPublicHealth–National
MedicalUniversityofWarsaw,Warsaw,Poland InstituteofHygiene,Warsaw,Poland
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