Table Of Content

IMMUNOLOGY REFERENCE EDITION TODAY Volume 12 1991 CONTENTS January page TRENDS To B, or not to B: that is the question Richard B. Gallagher and Dennis G. Osmond Lymphocytes play the music but the macrophage calls the tune Werner Solbach, Heidrun Moll and Martin Rollinghoff Today’s Immunology Today Richard B. Gallagher and Christine Doberska VIEWPOINT T-ceil development in the fetus and the invariant series hypothesis Richard Aspinall, Jaap Kampinga and Johan van den Bogaerde A mouse model for Borrelia burgdorferi infection: approach to a vaccine against Lyme disease M.M. Simon, U.E. Schaible, R. Wallich and M.D. Kramer 11 REVIEW Fibrogenic cytokines: the role of immune mediators in the development of scar tissue Elizabeth J. Kovacs 17 Barrier cells in the spleen 24 Leon Weiss Prominence of y8 T cells in the ruminant immune system Wayne R. Hein and Charles R. Mackay 30 Phosphatidylinositol membrane anchors and T-cell activation Peter J. Robinson 35 KALEIDOSCOPE Immunology Yesterday: The discovery of the immunological function of the thymus J.F.A.P. Miller 42 Letters 45 Book reviews 48 February TRENDS Bispecific antibodies and targeted cellular cytotoxicity Michael W. Fanger, David M. Segal and Jean-Loup Romet-Lemonne 51 New cytokines and receptors make their debut in San Antonio Scott K. Durum, Daniel G. Quinn and Kathrin Muegge 54 VIEWPOINT Genetic variation in the stress response: susceptibility to experimental allergic encephalomyelitis and implications for human inflammatory disease Don Mason 57 Autoimmunity to lysosomal enzymes: new clues to vasculitis and glomerulonephritis? C.G.M. Kallenberg, J.W. Cohen Tervaert, F.J. van der Woude, R. Goldschmeding, A.E.G. Kr. von dem Borne and J.J. Weening 61 REVIEW Special Feature: T-cell development Phenotypic and functional stages in the intrathymic development of aB T cells Janko Nikolié-Zugié 65 Towards an integrated view of thymopoiesis Richard L. Boyd and Patrice Hugo 71 T-cell development and transmembrane signaling: changing biological responses through an unchanging receptor Terri Helman Finkel, Ralph T. Kubo and John C. Cambier 79 Towards a molecular understanding of T-cell differentiation Hans C. Clevers and Michael J. Owen 86 KALEIDOSCOPE Letters 93 Book reviews 96 March Immunoparasitology Today INTRODUCTION Co-evolution of parasites and adaptive immune responses Graham F. Mitchell A2 NONSPECIFIC DEFENCE The acute phase protein response during parasitic infection Andrew W. Stadnyk and Jack Gauldie A7 The involvement of TNF, IL-1 and IL-6 in the immune response to protozoan parasites Richard G. Titus, Barbara Sherry and Anthony Cerami A13 Nonspecific defence mechanism: the role of nitric oxide F.Y. Liew and F.E.G. Cox Al17 Strategies of obligate intracellular parasites for evading host defences B. Fenton Hall and Keith A. Joiner A22 KEY MOLECULES Molecular genetics of antigenic variation Piet Borst A29 Antigenic polymorphism in malaria: is it an important mechanism for immune evasion? Kamini N. Mendis, Peter H. David and Richard Carter A34 Heat shock proteins in host—parasite interactions Barbara S. Polla A38 Genetic control of innate resistance to mycobacterial infections Erwin Schurr, Danielle Malo, Danuta Radzioch, Ellen Buschman, Kenneth Morgan, Philippe Gros and Emil Skamene A42 Life cycles A46 T-CELL SUBSETS The role of IL-10 in crossregulation of T,,1 and T,,2 responses Tim R. Mosmann and Kevin W. Moore A49 Regulation of the immune response in lymphatic filariasis and onchocerciasis Christopher L. King and Thomas B. Nutman AS4 Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function Richard M. Locksley and Phillip Scott Regulation and biological function of helminth-induced cytokine responses Fred D. Finkelman, Edward J. Pearce, Joseph F. Urban Jr and Alan Sher IMMUNOEPIDEMIOLOGY Naturally acquired immunity to Plasmodium falciparum Karen P. Day and Kevin Marsh Immunoepidemiology of lymphatic filariasis: the relationship between infection and disease Donald A.P. Bundy, Bryan T. Grenfell and P.K. Rajagopalan Helminths, immunology and equations Nicky Schweitzer and Roy Anderson TRENDS The molecular biology of MHC genes Roberto S. Accolla, Charles Auffray, Dinah S. Singer and John Guardiola Lymphocyte antigen receptors: a common design? Frits Koning VIEWPOINT Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis Jean Claude Ameisen and André Capron Autoimmunity, microbial immunity and the immunological homunculus Irun R. Cohen and Douglas B. Young REVIEW The distinctive specificity of antigen-specific suppressor T cells Eli Sercarz and Urszula Krzych Immunomodulation by ultraviolet light: clinical studies and biological effects D.H. Pamphilon, A.A. Alnaqdy and T.B. Wallington Antigen presentation: structural themes and functional variations Thomas J. Braciale and Vivian L. Braciale KALEIDOSCOPE From laboratory to clinic: the development of an immunological reagent Susan Bright, John Adair and David Secher Letters Book reviews TRENDS Rapamycin: FK506’s fraternal twin or distant cousin? Randall Ellis Morris More insights into the complex physiology of TNF Salem Chouaib, Didier Branellec and Wim A. Buurman VIEWPOINT Phospholipase A, — a mediator between proximal and distal effectors of inflammation W. Pruzanski and P. Vadas Staphylococcal-enterotoxin-dependent cell-mediated cytotoxicity Mikael Dohlsten, Gunnar Hedlund and Terje Kalland Thyroid-associated ophthalmopathy — a model for the association of organ-specific autoimmune disorders Jack R. Wall, Mario Salvi, Nicole F. Bernard, Andrée Boucher and David Haegert 150 REVIEW Natural autoantibodies: from ‘horror autotoxicus’ to ‘gnothi seauton’ S. Avrameas 154 Second generation immune networks Francisco J. Varela and Antonio Coutinho 159 KALEIDOSCOPE Immunology Yesterday: The discovery of thyroid autoimmunity Noel R. Rose 167 Letters 169 Book reviews 172 June TRENDS Tolerance and immune regulation Ellen Robey and Jacques Urbain 175 Immunotherapy of rheumatic diseases — practice and prospects Gabrielle Kingsley, Gabriel Panayi and Jerry Lanchbury 177 VIEWPOINT Primitive cytokines: harbingers of vertebrate defense Gregory Beck and Gail $. Habicht 180 The synergy between naive and memory T cells during activation Arne N. Akbar, Michael Salmon and George Janossy 184 T-cell memory: the connection between function, phenotype and migration pathways Charles R. Mackay 189 The dominant self and the cryptic self: shaping the autoreactive T-cell repertoire Guy Gammon, Eli E. Sercarz and Gilles Benichou 193 REVIEW The B-cell antigen receptor complex Michael Reth, Joachim Hombach, Jiirgen Wienands, Kerry S$. Campbell, Nadine Chien, Louis B. Justement and John C. Cambier 196 Signalling in B cells José E. Alés-Martinez, Eduardo Cuende, Carlos Martinez-A., R.M.E. Parkhouse, Luis Pezzi and David W. Scott 201 KALEIDOSCOPE Letters 206 Book reviews 208 July TRENDS Epitope mapping Angela C. Horsfall, Frank C. Hay, Andy J. Soltys and Meinir G. Jones 211 Hard graft? Future challenges in transplantation Robert Lechler, Richard B. Gallagher and Hugh Auchincloss 214 Peripheral lymph node homing receptor (LECAM-1) Donald C. Anderson, Eugene C. Butcher, Michael Gallatin et al. 216 VIEWPOINT Is amyloidogenesis during Alzheimer’s disease due to an IL-1-/1L-6-mediated ‘acute phase response’ in the brain? Peter Vandenabeele and Walter Fiers A new superfamily of cell surface proteins related to the nerve growth factor receptor Susan Mallett and A. Neil Barclay T,,2 cells in systemic autoimmunity: insights from allogeneic diseases and chemically-induced autoimmunity Michel Goldman, Philippe Druet and Ernst Gleichmann REVIEW Delayed-type hypersensitivity and cell-mediated immunity in the pathogenesis of tuberculosis Arthur M. Dannenberg, Jr Molecular targets in pernicious anaemia Paul A. Gleeson and Ban-Hock Toh 233 Cytokines in T-cell development Simon R. Carding, Adrian C.Hayday and Kim Bottomly 239 KALEIDOSCOPE Letters 246 Book reviews 250 August TRENDS Autoimmune myocarditis: concepts and questions Noel R. Rose, David A. Neumann and Ahvie Herskowitz 253 Immune parameters in HIV infection — a practical guide George Janossy 255 Human T,,1 and T,,2 subsets: doubt no more Sergio Romagnani 256 VIEWPOINT Mitogenic properties of major extracellular proteins Jean-Pierre Lévesque, Antoinette Hatzfeld and Jacques Hatzfeld 258 Recognition of self within self: specific lymphocyte positioning and the extracellular matrix Maria de Sousa, Nicholas L. Tilney and Jerzy W. Kupiec-Weglinski 262 What is the basis for HLA-DQ associations with autoimmune disease? Daniel M. Altmann, David Sansom and Steven G.E. Marsh 267 REVIEW The Mycoplasma arthritidis T-cell mitogen, MAM: a model superantigen Barry C. Cole and Curtis L. Atkin 271 T-cell recognition of myelin basic protein Kai W. Wucherpfennig, Howard L. Weiner and David A. Hafler 277 KALEIDOSCOPE Immunology Yesterday: Experiments of nature in the development of modern immunology Robert A. Good 283 Letters 287 Book reviews 288 September The biology of complement OVERVIEW Biology of complement: the overture Taroh Kinoshita 291 Evolution of the complement system Timothy C. Farries and John P. Atkinson 295 Complement deficiency and disease B. Paul Morgan and Mark J. Walport 301 MECHANISMS C1: molecular interactions with activating systems R.B. Sim and K.B.M.Reid 307 The control of homologous lysis Peter J. Lachmann 312 : Debate: the mechanism of complement lysis Big MAC attack: complement proteins cause leaky patches Alfred F. Esser 316 Complement lysis: a hole is a hole Sucharit Bhakdi and Jorgen Tranum-Jensen 318 INTERACTIONS The role of complement in inflammation and phagocytosis ; Michael M. Frank and Louis F. Fries 322 Complement evasion strategies of microorganisms Neil R. Cooper 327 The role of C3 in the immune response Anna Erdei, George Fiist and Janos Gergely 332 The response of human platelets to activated components of the complement system Peter J. Sims and Therese Wiedmer 338 October TRENDS Multiple interactions at the natural killer workshop Klas Karre, Mona Hansson and Rolf Kiessling 343 The role of T-cell subsets and cytokines in the regulation of infection Phillip Scott and Stefan H.E. Kaufmann 346 VIEWPOINT A new view of prostaglandin E regulation of the immune response Richard P. Phipps, Sidney H. Stein and Rachel L. Roper 349 Does antibody-dependent epitope masking permit progressive tumour growth in the face of cell-mediated cytotoxicity? Lionel A. Manson 352 REVIEW Mls — a retrovirus exploits the immune system Hans Acha-Orbea and Ed Palmer 356 Signalling through CSF receptors Gino Vairo and John A. Hamilton 362 Modulation of T-cell function by gliomas Thomas Roszman, Lucinda Elliott and William Brooks 370 KALEIDOSCOPE Science training for European journalists Byron H. Waksman 375 Letters 377 Book reviews 378 November TRENDS ISCOMS — a novel strategy for mucosal immunization? Allan Mcl. Mowat and Anne M. Donachie 383 How do peptides associate with MHC class I molecules? Tim Elliott 386 A new nomenclature for B cells Aaron B. Kantor et al. 388 The development and repertoire of B-1 cells (CDS B cells) Aaron B. Kantor 389 VIEWPOINT Functional subsets of allergen-reactive human CD4+* T cells Martien L. Kapsenberg, Eddy A. Wierenga, Jan D. Bos and Henk M. Jansen 392 Debate: the mechanism of lymphocyte-mediated killing Lymphocyte-triggered internal target disintegration Gideon Berke 396 Perforin-induced pore formation Olivier Krahenbihl and Jiirg Tschopp 399 REVIEW Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro Charles A. Dinarello and Robert C. Thompson 404 Shared epitopes among HLA class II alleles: gene conversion, common ancestry and balancing selection Henry A. Erlich and Ulf B. Gyllensten 411 Expression of perforin and granzymes in vivo: potential diagnostic markers for activated cytotoxic cells Gillian M. Griffiths and Christoph Mueller 415 KALEIDOSCOPE Letters 420 Book reviews 424 December TRENDS Modulation of MHC antigen expression by viruses and oncogenes D. John Maudsley and John D. Pound 429 VIEWPOINT On the nature and function of human uterine granular lymphocytes Ashley King and Yung Wai Loke 432 Extrathymic differentiation of intraepithelial lymphocytes: generation of a separate and unequal T-cell repertoire? Leo Lefrangois 436 Maintenance of immunological memory: a role for CDS* B cells? Fons UytdeHaag, Roger van der Heijden and Albert Osterhaus 439 Map of the human major histocompatibility complex John Trowsdale, Jiannis Ragoussis and R. Duncan Campbell 443 REVIEW Naturally-occurring peptide antigens derived from MHC class-I-restricted processing pathway Olaf Rétzschke and Kirsten Falk 447 X-linked immunodeficiencies: clues to genes involved in T- and B-cell differentiation Geneviéve de Saint Basile and Alain Fischer 456 KALEIDOSCOPE Budapest beckons Richard B. Gallagher and Janos Gergely Letters Book reviews Author Index Subject Index