Imaging Inside the Human Body g g y with Light g g y with Light PDF
Preview Imaging Inside the Human Body g g y with Light g g y with Light
Imaging Inside the Human Body withi Ltighht L i g h t Arjun G. Yodh University of Pennsylvania Department of Physics & Astronomy U n i v e r s i t y o f P e n n s y l v a n i a Goals • Dreams • Red/Near-infrared Transmission Window • Why is this hard? • How does light travel in the body? • Random Walks / Diffusion Models • Spectroscopy, Imaging, Blood Flow Monitoring • Primer on Blood Dynamics • Examples Breast Cancer Imaging, Stroke Monitoring U n i v e r s i t y o f P e n n s y l v a n i a The Dream. from: Star Trek from: Minority Report U n i v e r s i t y o f P e n n s y l v a n i a Red/Near-infrared Transmission Window • Near Infrared Light Penetrates Tissue • Non-invasive, safe, rapid, portable, continuous, inexpensive ... U n i v e r s i t y o f P e n n s y l v a n i a Why is this hard? Ice in Water Ice in Milk? U n i v e r s i t y o f P e n n s y l v a n i a Why is this hard? Water Water + Little Milk Milk Light doesn’t get Absorbed, it Scatters U n i v e r s i t y o f P e n n s y l v a n i a How does light travel in the body? "Random" Walk U n i v e r s i t y o f P e n n s y l v a n i a Random Walks and Diffusion U n i v e r s i t y o f P e n n s y l v a n i a Example: Random Walks from Philadelphia’s City Hall U n i v e r s i t y o f P e n n s y l v a n i a Example: Random Walks from Philadelphia’s City Hall U n i v e r s i t y o f P e n n s y l v a n i a
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