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neonatal Vol. 22 No. 7 November/December 2009 INTENSIVE CARE Human milk Blood Sampling aneStHeSia Bone diSeaSe StillBirtHS reSearcH Ventilation The first and only available CO detector indicated For patients with a body weight of 1 - 15 kg 2 for patients from 0.25 kg - 2 kgs - preemies/tiny babies Vivid breath-to-breath color change Vivid breath-to-breath color change Detects up to 50/breaths/minute Detects to 1 ml tidal volume 24-hour continuous performance Detects up to 100 breaths/minute Works in 100% humidity 24-hour continuous performance Convenient Pull Tab activates the device WWorks in 100% humidity Inspiratory Expiratory Neo-StatCO <KgTM or Mini StatCO ® effectively provides 2 2 24-hour performance with breath-to-breath color changes for ET Tube placement verification. PPlelaesaes veis ivt tihsei tM Berocourtyh M #e5di2ca8l ,B 9oo/2th3s - 9/26 Go to www.mercurymed.com for detailed information #N42A4N aNnd, #A42u6s atitn th, eT AeAxRaCs, San Antonio, Clearwater, Florida 33762-4807 ·(800) 237-6418 ·727-573-0088 Texas on December 5 - 7, 2009. Mercury Med EDIT ND09.indd 1 9/4/09 10:42:32 AM neonatal November/OVcotol.b 2e2r N2o00. 79 Editorial INTENSIVE CARE Perspective A recent article posted on e-medicine by Brian Carter of Vanderbilt University reminds neonatal healthcare practitioners not to lose sight of their goals. Dr Carter raises the following questions: Who deserves access to neonatal specialty care? Who pays for it? Are the costs acceptable? Is the distribution of care equitable? Are some babies too small or sick for care? What outcomes are too burdensome? Who decides about who gets care? How are these decisions made? But Carter points out that many of these questions are often vaguely posed, if at all, and typically in reverse order. He says neonatal caregivers may also wonder, Why are we doing this? Did we make a Vol. 22 No. 7 difference? What were we trying to accomplish with our efforts? Failing to approach and try to answer these questions, he says, leads to moral uncertainty and distress. November-December 2009 Another way to put the picture in perspective, he notes, is to posit the following questions before proceeding: what are the goals of neonatal intensive care? What place do guidelines have in ethical practice, and how should they be developed? What’s good for the infant, and who says so? Neonatal caregivers, he says, can’t simply say their job is to “save all babies,” or “reduce infant mortality.” The physical constraints of the Table of Contents NICU need to be considered, he says, and the ends to which care is provided should be kept in mind: Goals need to include more than the simple application of critical care technology, such as ventilators, monitors, medications, invasive devices, and a multiplicity of laboratory measurements, to sick and premature newborn patients. They should include stabilization of the newborn and, ultimately, facilitation of the DEPARTMENTS transition to normal, extrauterine, neonatal physiology. This transition takes longer 4 for some infants and may require significant intervention and support. The reversal of Editorial: Perspective acute disease processes, such as infection and respiratory distress, is one recognized 15 News end to aim for. Care should be provided, he says, with a reasonable expectation of steady improvement, and shouldn’t cause needless pain. When apportioning care, 20 Monitoring the “capacity for the newborn to enjoy and participate in the human experience over a life prolonged beyond infancy” must be considered. Carter also reminds us 21 Products that “parents are considered to be the spokespersons [for infants], and thus their input must be considered, and that decisions should be shared and communicated among all parties.” Finally, he says, data about outcomes can’t rely solely on national, generalized information, because it may not apply to the local situation. Carter ARTICLES notes, “Perhaps the final consideration in answering these questions is that each day, 13 healthcare professionals must work within the realities of the cases before them. Commentary: WIC vs Breastfeeding Each patient has a unique set of problems that prompt action, moral reflection, 22 and reevaluation. Each healthcare dilemma reminds caregivers of their limitations, Human Milk in the NICU including uncertainty, the human predicament, lack of knowledge, and decision- 27 Umbilical Blood Sampling making abilities. All of these are tempered by the moral constraints under which they act. Healthcare professionals must, at times, accept the reality that tragic cases have 29 Anesthesia for C-Sections tragic outcomes… [The practitioner is] asked to not only inquire, ‘What good are we doing here?’ but also to move toward defining goals for the individual patient.” 33 Bone Disease and Nutrition 39 Stillbirth Intervention 44 Vaginal vs Cesarean 47 Les Plesko, Editor Maternal Health 56 Prioritizing Research From E-medicine, Ethical Issues in Neonatal Care, Brian S. Carter, MD, FAAP, Professor of Pediatrics (Neonatology), Vanderbilt University School of Medicine; Co- 58 ASV Mode for Ventilation director, Pediatric Advance Comfort Team, Monroe Carell Jr Children’s Hospital at Vanderbilt. http://emedicine.medscape.com. From WebMD. All material on the website is protected by copyright, Copyright© 1994-2009 by Medscape. 4 neonatal INTENSIVE CARE Vol. 22 No. 7 n November-December 2009 Special Delivery... BiliSoft™ LED Phototherapy System The next generation LED and fi beroptic based technology for treatment of indirect hyperbilirubinemia in newborns. Increased surface area, high spectral irradiance, and long lasting blue narrow-band LED light provide intensive, effi cacious phototherapy as recommended by AAP Guidelines. Plus, it supports and promotes developmental care, enables infant-parent bonding and provides healing light where it is needed – in the Neonatal ICU, Pediatrics, Well Baby Nursery and at home. Announcing the latest additions to our Maternal-Infant Care family. We have given birth to a series of new, innovative solutions in microenvironments, phototherapy, resuscitation, intra-hospital mobility, monitoring, information solutions, ventilation, and education. Together we can re-think, re-invent, and re-discover. For more information visit www.gehealthcare.com/perinatal or call 800-558-5120, select Option 7, then Option 3 (8am – 5pm CDT) to speak with a Maternal-Infant Care representative. A B D © 2009 General Electric Company – All rights reserved. GE and GE Monogram are trademarks of General Electric Company. GEHC_NICU_Oct09_v1.indd 1 7/27/09 1:26:27 PM Editorial Advisory Board Arie L. Alkalay, MD Ivan Frantz, III, MD Ataturk School of Medicine Clinical Professor of Pediatrics Professor of Pediatrics Erzurum, Turkey UCLA School of Medicine Chief, Division of Newborn Medicine Published seven times each year by Los Angeles, CA Tufts University School of Medicine Michael O’Shea Boston, MA Wake Forest University School of Medicine Goldstein and Associates, M. A. Arif, MD Winston-Salem, NC Professor of Pediatrics & Head, Philippe S. Friedlich, MD Inc. Neonatology Assistant Professor of Pediatrics G. Battisita Parigi, MD National Institutes of Child Health Keck School of Medicine Associate Professor of Pediatric Surgery 10940 Wilshire Blvd., Suite 600 Karachi, Pakistan University of Southern California University of Pavia Los Angeles CA 90024 Los Angeles, CA Italy Muhammad Aslam, MD Phone: 310-443-4109 Clinical Fellow in Newborn Medicine G. Paolo Gancia, MD Richard Paul, MD Harvard Neonatal-Perinatal Fellowship Neonatologist, Terapia Intensiva Chief, Maternal & Fetal Medicine Fax: 310-443-4110 Program Neonatale-Neonatologia Department of Obstetrics & Gynecology E-mail: [email protected] Children’s Hospital Boston Cuneo, Italy University of Southern California Harvard Medical School/ Harvard Los Angeles, CA Web: www.nicmag.ca University, Boston, MA. GPreoofersgsoer Aof. PGerdeiagtoricrsy ,a nMdD A nesthesia Max Perlman, MD Publisher Edward Austin, MD University of California Professor of Pediatrics Steve Goldstein APesdsiisattarinct SCulringiecrayl Professor San Francisco, CA TThoero Hntoos,p Oitnatl aforiro ,S Cicakn Cahdialdren ELdesit Porlesko USanniv Ferrasnitcyi socfo C, CalAifornia-San Francisco WNDeeipollaniraattmmale RnRte. soHpf iarRaleltisobpryiur arCttaoorreny ,CC RoaorRerT d,i nRaCtoPr BProorfeiss sPoer torf iOkbosvtestkriyc,s ManDd Gynecology Richard L. Auten, MD Hillcrest Baptist Medical Center Nassau Health Care Corporation Senior Editor Assistant Professor of Pediatrics Waco, TX East Meadow, NY Carol Brass DDuukrhea Umn, ivNeCrsity Medical Center MAsasorcyi aCtea tPhroefreisnsoer Hofa Prerdisia, tMricDs APrroufens sPorra omf Paendiiakt,r iMcsD Associate Editor Bruce G. Bateman, MD Division of Neonatology Section of Neonatology Department of Obstetrics & Gynecology University of Pennsylvania School of Louisiana State University Laszlo Sandor University of Virginia Medicine Health Sciences Center Charlottesville, VA The Children’s Hospital of Medicine Shreveport, LA Design, Typography, Prepress and Production Management DWaakvei dF oDre. sBt eUrnriyve, rMsitDy School of Medicine PDhailvaidde lJp.h Hiao, fPfAman, MD BCheinefa omf aNneoanhaatolllio Kgy. Rajegowda, MD http://accugraphics.net Winston-Salem, NC Clinical Associate Professor of Pediatrics Lincoln Medical and Mental Health Center Penn State College of Medicine Professor of Clinical Pediatrics Circulation, Coverage, Advertising D. Spencer Brudno, MD Staff Neonatologist Weill Medical College of Cornell University, Rates: Complete details regarding Associate Professor of Pediatrics The Reading Hospital and Medical Center NY Medical Director, Pediatric Therapy circulation, coverage, advertising Medical College of Georgia West Reading, PA Koravangattu Sankaran, FRCP(C), rates, space sizes, and similar Augusta, GA Michael R. Jackson, RRT FAAP, FCCM CWN 6 Neonatal Respiratory Care Professor of Pediatrics and Director of information are available to Curtis D. Caldwell, NNP Brigham & Women’s Hospital Neonatology and Neonatal Research prospective advertisers. Closing date UNM School of Medicine Boston, MA Department of Pediatrics Department of Pediatrics Royal University Hospital is 45 days preceding date of issue. Albuquerque, NM Chang-Ryul Kim, MD University of Saskatchewan Associate Professor of Pediatrics Saskatoon, Saskatchewan, Canada Change of Address notices should Ed Coombs, MA, RRT College of Medicine be sent promptly to Circulation Sr. Marketing Manager - Ventilation Hanyang University Kuri Hospital Istvan Seri, MD, PhD Department: provide old mailing DTerlafeogrde,r PMAedical Seoul, South Korea PHreoafde,s sUoSrC o fD Piveidsiioantr iocsf Neonatal Medicine label as well as new address: include David M. Kissin BS, RRT University of Southern California Jonathan Cronin, MD Perinatal/Pediatric Specialist Los Angeles, CA zip code or postal code. Allow two Associate Chief of Neonatology Maine Medical Center months for change. Massachusetts General Hospital for Portiand, ME Otwell D. Timmons, MD Children Assistant Professor of Pediatrics Editorial Contributions may be Harvard Medical School Sheldon Korones, MD University of Utah Medical Center Cambridge, MA Director of Newborn Center Salt Lake City, UT sent by e-mail and will be handled College of Medicine with reasonable care: however, Michael P. Czervinske, RRT Memphis, TN Maya Vazirani, MD, FAAP Neonatal and Pediatric Critical Care Board Certified Neonatology and publishers assume no responsibility University of Kansas Medical Center Raymond Malloy, BS, RRT Pediatrics for safety of art work, photographs, Kansas City, KS Director of Pulmonary Care Lancaster, CA or manuscripts. Every precaution Professor Adekunle H. Dawodu TPhhoilmadaesl pJehfiafe, rPsAon University Hospital Max Vento, MD is taken to ensure accuracy, but Chairman of Pediatrics Associate Professor of Pediatrics Faculty of Medicine and Health Sciences Paul J. Mathews, PhD, RRT, Chief, Pediatric Services the publishers cannot accept United Arab Emirates University FCCM, FCCP, FAARC Neonatologia Hospital Virgin del Consuelo responsibility for the correctness Al Anin, UAE Associate Professor of Respiratory Care Valencia, Spain or accuracy of informa tion supplied University of Kansas Medical Center Jayant Deodhar, MD Kansas City, KS Dharmapuri Vidyasagar, MD herein or for any opinion expressed. Associate Professor of Clinical Pediatrics Professor of Pediatrics Editorial closing date is the first day Children’s Hospital Center William Meadow, MD Department of Pediatrics Cincinnati, OH Associate Professor University of Illinois of the month preceding month of Department of Pediatrics Chicago, IL issue. Leonard Eisenfeld, MD The University of Chicago Associate Professor of Pediatrics Chicago, IL University of Connecticut School of ©2009 by Goldstein & Associates, Medicine David G. Oelberg, MD Inc. All rights reserved. Reproduction Division of Neonatology Center for Pediatric Research in whole or in part without written Connecticut Children’s Medical Center Eastern Virginia Medical School Hartford, CT Children’s Hospital of The King’s Daughters permission is strictly prohibited. Norfolk, VA Sami Elhassani, MD Neonatologist Rahmi Ors, MD Spartanburg, SC Chief, Division of Neonatology 6 neonatal INTENSIVE CARE Vol. 22 No. 7 n November-December 2009 INL-006 NIC-RT.eps 8/9/07 9:10:19 AM B G R 0 0 1 5 9 kc 75 a Bl 50 5 2 5 0 0 1 5 9 w 5 o 7 Yell 50 5 2 5 0 0 1 5 9 a t 5 n 7 e g 0 a 5 M 5 2 5 0 0 1 5 9 5 n 7 a y 0 C 5 5 2 5 BLACKYELLOWMAGENTACYAN INL-006_NIC-RT_1-Page 1.pgs 08.09.2007 09:17 NEW_NICMagAdQuiet5.qxd:NIC Mag Ad Quiet 5.qxd 9/3/09 11:42 AM Page 1 High-Frequency Ventilation now just a whisper. T h e B u n n e l l L i f e P u l s e H F V w i t h n e w s o u n d 4 decibels below r e d u c t i o n t e c h n o l o g y is the A m e r i c a n A c a d e m y o f P e d i a t r i c s ’ s o u n d l e v e l recommendation for the NICU. This upgrade represents a 60% sound reduction from our current mod e l. If High-Frequency ventilator noise is a concern in your NICU, you should evaluate the Life Pulse. Call Bunnell for a free trial and experience the difference for yourself. Quiet is only a phone call away. 800.800.4358 ext. 15 Neopuff™ Infant T-Piece Resuscitator Continuing to raise the standard of care in infant resuscitation THE NEOPUFF™ INFANT T-PIECE RESUSCITATOR PROVIDES OPTIMAL RESUSCITATION BY DELIVERING CONTROLLED PIP AND CONSISTENT PEEP. (cid:59)(cid:77)(cid:88)(cid:76)(cid:4)(cid:83)(cid:90)(cid:73)(cid:86)(cid:4)(cid:22)(cid:20)(cid:4)(cid:93)(cid:73)(cid:69)(cid:86)(cid:87)(cid:4)(cid:83)(cid:74)(cid:4)(cid:91)(cid:83)(cid:86)(cid:80)(cid:72)(cid:91)(cid:77)(cid:72)(cid:73)(cid:4)(cid:89)(cid:87)(cid:73)(cid:4)(cid:69)(cid:82)(cid:72)(cid:4)(cid:69)(cid:71)(cid:71)(cid:73)(cid:84)(cid:88)(cid:69)(cid:82)(cid:71)(cid:73)(cid:4) (cid:77)(cid:82)(cid:90)(cid:83)(cid:80)(cid:90)(cid:77)(cid:82)(cid:75)(cid:4)(cid:81)(cid:77)(cid:80)(cid:80)(cid:77)(cid:83)(cid:82)(cid:87)(cid:4)(cid:83)(cid:74)(cid:4)(cid:87)(cid:69)(cid:74)(cid:73)(cid:4)(cid:69)(cid:82)(cid:72)(cid:4)(cid:73)(cid:74)(cid:74)(cid:73)(cid:71)(cid:88)(cid:77)(cid:90)(cid:73)(cid:4)(cid:86)(cid:73)(cid:87)(cid:89)(cid:87)(cid:71)(cid:77)(cid:88)(cid:69)(cid:88)(cid:77)(cid:83)(cid:82)(cid:87)(cid:18) (cid:56)(cid:76)(cid:73)(cid:4)(cid:50)(cid:73)(cid:83)(cid:84)(cid:89)(cid:74)(cid:74)(cid:141)(cid:4)(cid:45)(cid:82)(cid:74)(cid:69)(cid:82)(cid:88)(cid:4)(cid:56)(cid:17)(cid:52)(cid:77)(cid:73)(cid:71)(cid:73)(cid:4)(cid:54)(cid:73)(cid:87)(cid:89)(cid:87)(cid:71)(cid:77)(cid:88)(cid:69)(cid:88)(cid:83)(cid:86)(cid:4)(cid:71)(cid:83)(cid:82)(cid:88)(cid:77)(cid:82)(cid:89)(cid:73)(cid:87)(cid:4)(cid:88)(cid:83)(cid:4) (cid:86)(cid:69)(cid:77)(cid:87)(cid:73)(cid:4)(cid:88)(cid:76)(cid:73)(cid:4)(cid:87)(cid:88)(cid:69)(cid:82)(cid:72)(cid:69)(cid:86)(cid:72)(cid:4)(cid:83)(cid:74)(cid:4)(cid:71)(cid:69)(cid:86)(cid:73)(cid:4)(cid:74)(cid:83)(cid:86)(cid:4)(cid:77)(cid:82)(cid:74)(cid:69)(cid:82)(cid:88)(cid:4)(cid:86)(cid:73)(cid:87)(cid:89)(cid:87)(cid:71)(cid:77)(cid:88)(cid:69)(cid:88)(cid:77)(cid:83)(cid:82)(cid:18) (cid:56)(cid:83)(cid:4)(cid:73)(cid:92)(cid:84)(cid:73)(cid:86)(cid:77)(cid:73)(cid:82)(cid:71)(cid:73)(cid:4)(cid:88)(cid:76)(cid:73)(cid:4)(cid:50)(cid:73)(cid:83)(cid:84)(cid:89)(cid:74)(cid:74)(cid:4)(cid:45)(cid:82)(cid:74)(cid:69)(cid:82)(cid:88)(cid:4)(cid:56)(cid:17)(cid:52)(cid:77)(cid:73)(cid:71)(cid:73)(cid:4)(cid:54)(cid:73)(cid:87)(cid:89)(cid:87)(cid:71)(cid:77)(cid:88)(cid:69)(cid:88)(cid:83)(cid:86)(cid:4) (cid:84)(cid:80)(cid:73)(cid:69)(cid:87)(cid:73)(cid:4)(cid:90)(cid:77)(cid:87)(cid:77)(cid:88)(cid:4)(cid:89)(cid:87)(cid:4)(cid:69)(cid:88)(cid:4)(cid:88)(cid:76)(cid:73)(cid:4)(cid:37)(cid:59)(cid:44)(cid:51)(cid:50)(cid:50)(cid:4)(cid:22)(cid:20)(cid:20)(cid:29)(cid:4)(cid:39)(cid:83)(cid:82)(cid:90)(cid:73)(cid:82)(cid:88)(cid:77)(cid:83)(cid:82)(cid:4)(cid:77)(cid:82)(cid:4)(cid:4) (cid:55)(cid:69)(cid:82)(cid:4)(cid:40)(cid:77)(cid:73)(cid:75)(cid:83)(cid:18)(cid:4)(cid:4)(cid:51)(cid:86)(cid:4)(cid:71)(cid:69)(cid:80)(cid:80)(cid:4)(cid:89)(cid:87)(cid:4)(cid:83)(cid:82)(cid:4)(cid:12)(cid:28)(cid:20)(cid:20)(cid:13)(cid:4)(cid:24)(cid:24)(cid:26)(cid:17)(cid:23)(cid:29)(cid:20)(cid:28)(cid:4)(cid:69)(cid:82)(cid:72)(cid:4)(cid:91)(cid:73)(cid:171)(cid:80)(cid:80)(cid:4)(cid:4) (800) 446-3908 (cid:75)(cid:80)(cid:69)(cid:72)(cid:80)(cid:93)(cid:4)(cid:71)(cid:83)(cid:81)(cid:73)(cid:4)(cid:69)(cid:82)(cid:72)(cid:4)(cid:90)(cid:77)(cid:87)(cid:77)(cid:88)(cid:4)(cid:93)(cid:83)(cid:89)(cid:18) [email protected] F&P INFANT RESPIRATORY CARE CONTINUUM RESUSCITATION INVASIVE NON-INVASIVE NASAL FACE MASK LOW FLOW HUMIDITY VENTILATION VENTILATION HIGH FLOW OXYGEN (cid:42)(cid:77)(cid:87)(cid:76)(cid:73)(cid:86)(cid:4)(cid:10)(cid:4)(cid:52)(cid:69)(cid:93)(cid:79)(cid:73)(cid:80)(cid:4)(cid:44)(cid:73)(cid:69)(cid:80)(cid:88)(cid:76)(cid:71)(cid:69)(cid:86)(cid:73)(cid:16)(cid:4)(cid:21)(cid:25)(cid:23)(cid:26)(cid:25)(cid:4)(cid:38)(cid:69)(cid:86)(cid:86)(cid:69)(cid:82)(cid:71)(cid:69)(cid:4)(cid:52)(cid:69)(cid:86)(cid:79)(cid:91)(cid:69)(cid:93)(cid:16)(cid:4)(cid:45)(cid:86)(cid:90)(cid:77)(cid:82)(cid:73)(cid:16)(cid:4)(cid:39)(cid:37)(cid:4)(cid:29)(cid:22)(cid:26)(cid:21)(cid:28)(cid:4)(cid:57)(cid:55)(cid:37)(cid:4) (cid:56)(cid:73)(cid:80)(cid:4)(cid:17)(cid:4)(cid:28)(cid:20)(cid:20)(cid:4)(cid:24)(cid:24)(cid:26)(cid:4)(cid:23)(cid:29)(cid:20)(cid:28)(cid:4)(cid:83)(cid:86)(cid:4)(cid:15)(cid:21)(cid:4)(cid:29)(cid:24)(cid:29)(cid:4)(cid:24)(cid:25)(cid:23)(cid:4)(cid:24)(cid:20)(cid:20)(cid:20)(cid:4)(cid:4)(cid:42)(cid:69)(cid:92)(cid:4)(cid:17)(cid:4)(cid:15)(cid:21)(cid:4)(cid:29)(cid:24)(cid:29)(cid:4)(cid:24)(cid:25)(cid:23)(cid:4)(cid:24)(cid:20)(cid:20)(cid:21) 1338_RH Neopuff Ad_Re-size.indd 1 23/6/09 11:08:52 AM Improved Outcomes. Real-Time Data Accuracy. Based on clinical evidence, INVOS® System labeling for site- specifi c blood oxygen monitoring has been expanded. This makes it the only commercially-available cerebral/somatic oximeter to be backed by the following claims. (cid:116)(cid:1) (cid:42)(cid:78)(cid:81)(cid:83)(cid:80)(cid:87)(cid:70)(cid:69)(cid:1)(cid:80)(cid:86)(cid:85)(cid:68)(cid:80)(cid:78)(cid:70)(cid:84)(cid:1)(cid:66)(cid:71)(cid:85)(cid:70)(cid:83)(cid:1)(cid:68)(cid:66)(cid:83)(cid:69)(cid:74)(cid:66)(cid:68)(cid:1)(cid:80)(cid:83)(cid:1)(cid:78)(cid:66)(cid:75)(cid:80)(cid:83)(cid:1)(cid:72)(cid:70)(cid:79)(cid:70)(cid:83)(cid:66)(cid:77)(cid:1)(cid:84)(cid:86)(cid:83)(cid:72)(cid:70)(cid:83)(cid:90)(cid:1)(cid:74)(cid:79)(cid:1) patients > 2.5 kg (cid:116)(cid:1) (cid:48)(cid:79)(cid:14)(cid:77)(cid:66)(cid:67)(cid:70)(cid:77)(cid:1)(cid:85)(cid:83)(cid:70)(cid:66)(cid:85)(cid:78)(cid:70)(cid:79)(cid:85)(cid:1)(cid:80)(cid:71)(cid:1)(cid:81)(cid:66)(cid:85)(cid:74)(cid:70)(cid:79)(cid:85)(cid:84)(cid:1)(cid:66)(cid:85)(cid:1)(cid:66)(cid:79)(cid:90)(cid:1)(cid:88)(cid:70)(cid:74)(cid:72)(cid:73)(cid:85)(cid:1) (cid:1) (cid:80)(cid:1) (cid:31)(cid:1)(cid:19)(cid:15)(cid:22)(cid:1)(cid:76)(cid:72)(cid:27)(cid:1)(cid:83)(cid:70)(cid:66)(cid:77)(cid:14)(cid:85)(cid:74)(cid:78)(cid:70)(cid:1)(cid:69)(cid:66)(cid:85)(cid:66)(cid:1)(cid:66)(cid:68)(cid:68)(cid:86)(cid:83)(cid:66)(cid:68)(cid:90) o < 2.5 kg: trend monitoring (cid:116)(cid:1) (cid:47)(cid:80)(cid:79)(cid:74)(cid:79)(cid:87)(cid:66)(cid:84)(cid:74)(cid:87)(cid:70)(cid:1)(cid:74)(cid:79)(cid:69)(cid:74)(cid:68)(cid:66)(cid:85)(cid:74)(cid:80)(cid:79)(cid:1)(cid:80)(cid:71)(cid:1)(cid:48) changes in the cerebral and 2 (cid:81)(cid:70)(cid:83)(cid:74)(cid:81)(cid:73)(cid:70)(cid:83)(cid:66)(cid:77)(cid:1)(cid:68)(cid:74)(cid:83)(cid:68)(cid:86)(cid:77)(cid:66)(cid:85)(cid:80)(cid:83)(cid:90)(cid:1)(cid:84)(cid:90)(cid:84)(cid:85)(cid:70)(cid:78)(cid:84) o Often providing an early warning of O defi cits associated 2 with impending shock and anaerobiosis Labeling claims not applicable to other devices as data was derived using the INVOS System and its proprietary algorithm. © Somanetics Corporation. Somanetics, INVOS and “Refl ecting the color of life” are registered trademarks of Somanetics Corporation. US federal regulations restrict the sale of this device to, or on the order of, licensed medical practitioners. Learn more at www.somanetics.com | 800.359.7662 Somanetics_NeonatalIntensiveCare_Jun09_SMS1084.indd 1 5/7/09 9:25:32 PM

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