HPV and Head and Neck Cancers PDF
Preview HPV and Head and Neck Cancers
Head and Neck Cancer Clinics Series Editors: Rehan Kazi · Raghav C. Dwivedi Carole Fakhry Gypsyamber D’Souza Editors HPV and Head and Neck Cancers Head and Neck Cancer Clinics Series editors Rehan Kazi Head and Neck Cancer Manipal University Manipal, Karnataka , India Raghav C. Dwivedi Head and Neck Cancer Royal Marsden Hospital London , United Kingdom Other titles in the series Clinical Approach to Well-Differentiated Thyroid Cancers Frederick L. Greene and Andrzej L. Komorowski Tumours of the Skull Base and Paranasal Sinuses Ziv Gil and Dan M. Fliss Controversies in Oral Cancer K.A. Pathak and Richard W. Nason Management of Thyroid Cancer: Special Considerations K.A. Pathak, Richard W. Nason and Janice L. Pasieka Non-Melanoma Skin Cancer of the Head and Neck Faruque Riffat, Carsten E. Palme and Michael Veness Carole Fakhry (cid:129) Gypsyamber D’Souza Editors HPV and Head and Neck Cancers Editors Carole Fakhry Gypsyamber D’Souza Oto-Head and Neck Surgery Epidemiology Johns Hopkins University School Johns Hopkins Bloomberg School Baltimore , Maryland Baltimore , Maryland USA USA ISSN 2364-4060 ISSN 2364-4079 (electronic) Head and Neck Cancer Clinics ISBN 978-81-322-2412-9 ISBN 978-81-322-2413-6 (eBook) DOI 10.1007/978-81-322-2413-6 Library of Congress Control Number: 2015944199 Springer New Delhi Heidelberg New York Dordrecht London © Carole Fakhry, Gypsyamber D’Souza, Rehan Kazi and Raghav C. Dwivedi 2015 T his work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifi cally the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfi lms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. T he use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specifi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. T he publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Cover illustration by Dan Gibbons DCR(R), PgCert(CT) Printed on acid-free paper S pringer New Delhi Heidelberg New York Dordrecht London is part of Springer Science+Business Media (www.springer.com) Byword Books Private Limited, Delhi, India (www.bywordbooks.in) This series is dedicated to the research and charity efforts of Cancer Aid and Research Foundation (CARF), Mumbai, India (www.cancerarfoundation.org). A Note on the Series H ead and Neck Cancer (HNC) is a major challenge to public health. Its manage- ment involves a multidisciplinary team approach, which varies depending on the subtle differences in the location of the tumour, stage and biology of disease and availability of resources. In the wake of rapidly evolving diagnostic technologies and management techniques, and advances in basic sciences related to HNC, it is important for both clinicians and basic scientists to be up-to-date in their knowledge of new diagnostic and management protocols. This series aims to cover the entire range of HNC-related issues through independent volumes on specifi c topics. Each volume focuses on a single topic relevant to the current practice of HNC, and con- tains comprehensive chapters written by experts in the fi eld. The reviews in each volume provide vast information on key clinical advances and novel approaches to enable a better understanding of relevant aspects of HNC. Individual volumes pres- ent different perspectives and have the potential to serve as stand-alone reference guides. We believe these volumes will prove useful to the practice of head and neck surgery and oncology, and medical students, residents, clinicians and general prac- titioners seeking to develop their knowledge of HNC will benefi t from them. Manipal, Karnataka, India Rehan Kazi London, UK Raghav C. Dwivedi vii Foreword Dr. Jatin P. Shah The publishers (Byword Books) and the Series Editors Drs. Rehan Kazi and Raghav Dwivedi are to be complimented for conceiving and introducing the ‘Head and Neck Cancer Clinics’ series, a much-needed educational and informational resource on focused topics with contributions from world leaders in the specialty of head and neck oncology. The selection of topics and volume editors is crucial to the success of this series, and the volumes published to date, or to be published as listed, clearly refl ect that this series is bound to succeed and here to stay. T he current volume on ‘Human Papillomavirus and Head and Neck Cancers’ is very timely and much needed to bring to fore the many misconceptions and lacunae in knowledge about this ‘new entity’ in the arena of clinical care of head and neck cancer patients, by all involved specialists. The editors, Drs. Carole Fakhry and Gypsyamber D’Souza, from the Johns Hopkins Medical Center, have assembled an outstanding group of authors in this volume, all of whom are world leaders in their area of interest, with their contributions culminating into an up-to-date status report. Clearly, this is the most concise treatise on this topic with state-of-the-art informa- tion available today. T he global incidence of HPV infections is rising, and so is the incidence of HPV- related cancers in the head and neck, particularly in the oropharynx (OPC), while there is a steady decline in tobacco-induced OPCs. Misconceptions about the role of HPV-positivity and promiscuity are sensitive, personal and social issues and need ix
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