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Hospital Physician 2005: Vol 41 Index PDF

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2005 Index KEY: Bakanas E Review questions: neurobiology of mood CB = Code Blue Stories A 54-year-old man with fever, skin rash, and disorders, 41 (9):36, 43 (RQ) CPE = Clinical Practice Exam oral ulcers, 41 (12):22—24, 32 (CPE) DocesJ G CR = Case Report Barry TB Sudden cardiac death in a 30-year-old preg- CRA = Clinical Review Article A slight resemblance, 41(8):18 (CB) nant woman, 41 (2):37—41 (CR) GR = Geriatric Rounds Beckman HB D’Silva KJ IDU = Infectious Diseases Update Finding the practice that is right for you: tips Atypical presentation of hepatocellular car- LE = Letter to the Editor for a successfujlo b search after residency, cinoma, 41 (9):33-—35, 52 (CR) PLI = Primer in Literature Interpretation 41(4):52-63 (SMP) Dwivedi AJ PR = Pediatric Rounds Bhalodia R Atypical presentation of hepatocellular car- RCS = Review of Clinical Signs A 54-year-old man with fever, skin rash, and cinoma, 41 (9):33-—35, 52 (CR) RQ = Review Questions oral ulcers, 41 (12):22-24, 32 (CPE) El-Hakim A SA = State oft he Art Bhatt DL Robotic laparoscopic radical prostatectomy, SAQ = Self-Assessment Questions Mechanical complications of acute myocar- 41(9):37—43 (SA) SMP = Seminars in Medical Practice article dial infarction: review questions, 41 (5): Espinas P 23-24 (SAQ) A helpful clinical pearl, 41 (2):42 (CB) AUTHOR/EDITOR Blackman SC Fama T Adigun AQ Headache and forehead swelling in a 9-year- Do no harm, 41 (10):30 (CB) Cardiac resynchronization therapy for treat- old boy with sinusitis, 41 (2):43—49 (PR) FaulknerJ M Borden WB ment of congestive heart failure, 41 (1): Acute disseminated encephalomyelitis in a 15-17, 24 (SA) Approach to routine interactions with indus- 4-year-old girl, 41(5):37—43 (CR) try: a primer for residents, 41 (10):55-63 Adler DG FrohnaJ G DxRay: a 70-year-old man with an abdomi- (SMP) Applying evidence to decisions about col- Carlone V nal mass, 41 (1):29-—34 (CPE) orectal cancer screening: how to use a Gastrointestinal and liver disease during Thyrotoxicosis, 41 (3):46-56 (CRA) clinical practice guideline, 41 (6):45—56 pregnancy: review questions, 41 (2):29-30 Carolan PL (SMP) (SAQ) Acute disseminated encephalomyelitis in a Finding current best evidence in the care of a Malabsorption and vitamin deficiencies due 4+-year-old girl, 41(5):37—43 (CR) patient with possible pulmonary embolism: Chan MR to gastrointestinal illness: review ques- how to use evidence resources, 41 (2): Acute abdomen in a patient with systemic tions, 41 (6):35-36 (SAQ) 50-60 (SMP) Metastatic cancers of unknown primary site, lupus erythematosus, 41 (4):27-31 (CR) Funnell MA 41(4):33-40 (CRA) Chang SS Medication errors involving “L insulins,” A 55-year-old man with chest pain, 41(11): Severe hypertension in an adolescent girl, 41 (6):19-22, 40 (CRA) 17-20 (CPE) 41(9):27-32 (PR) Review questions: medication errors involv- Al Chekakie MO CharlesJ C ing “L insulins,” 41 (6):39-40, 44 (RQ) EGG 41(9i)nt:e1r0p r(eLtEa)t ion and digoxin toxicity, CMehtaaubhoalni c Ka cidosis, 41 (3):37—42 (CRA) Gaffar M Upper extremity deep vein thrombosis, A 93-year-old woman with an abnormal Review questions: shock with jugular venous 41(6):29-34 (CRA) electrocardiogram, 41 (6):23-25, 40 distention, 41 (10):36, 56 (RQ) Gandhi HA (CPE) Shock with jugular venous distention, 41 (10): Al-Halaseh W 17-24, 29 (CRA) An unusual case of orbital metastasis from adenocarcinoma of prostate, 4] (6):41-—43 Right ventricular thrombus mimicking a Chavda K myxoma in a 19-year-old man, 41 (8): A vegetarian with neurocysticercosis, 41 (3):2 Gen(uCaRr)d i F] 39-42, 56 (CR) (LE) Alangaden GJ Coca SG Pedi$a1 t(r9i)c :4g5a-s4t6r oe(nStAeQro)l ogy: review questions, Hospital epidemiology and infection con- Strategies to prevent radiocontrast nephrop- Giardino AP trol: review questions, 41 (3):25-26 (SAQ) athy, 41 (11):29-38 (CRA) Alkotob ML Coffman DR Headache and forehead swelling in a 9-year- old boy with sinusitis, 41 (2):43-—49 (PR) A 93-year-old woman with an abnormal elec- Pertussis, 41 (7):44—52 (CRA) trocardiogram, 41 (6):23-25, 40 (CPE) Crawford-Faucher AD A 3:month-old girl with a persistent cough Anastasopoulou C A 3-month-old girl with a persistent cough and respiratory distress, 41 (7):35—42 (PR) Diagnosis and treatment of pituitary gland and respiratory distress, 41 (7):35—42 (PR) Severe hypertension in an adolescent girl, disorders: review questions, 41 (8):29-30 Daubert GP 41 (9):27—32 (PR) (SAQ) EGG interpretation and digoxin toxicity, Gisondi MA Anderson ML 41(9):10 (LE) Basic principles of informed consent in the Osteoarthritis, 41(7):17—24, 42, (CRA) Dec GW acute care setting, 41(4):45-—52 (SMP) Review questions: osteoarthritis, 41 (7):34, 52 Asymmetric ST-segment elevations in menin- Glister BC (RQ) gococcal meningitis, 41 (11):25-27 (CR) Hypertriglyceridemia, 41 (3):17-24 (CRA) Arora V DeGregorioJ Goldberg LH Approach to routine interactions with indus- Right ventricular thrombus mimicking a A survey of hospice and palliative care part try: a primer for residents, 41 (10):47—55 myxoma in a 19-year-old man, 41 (8): 2: therapeutic interventions, 41 (1):45—52, (SMP) 39-42, 56 (CR) 60 (CRA) AtriA Dilda V Goodman S$ Differential diagnosis of common demen- Neurobiology of mood disorders, 41 (9): Anemias of bone marrow failure, 41 (2):19-26 tias: review questions, 41 (4):25-26 (SAQ) 17-26, 43 (CRA) (CRA) Hospital Physician December 2005 45 www.turner-white.com 2005 Index Grabowski MV JewellJ A Lievense S Sudden cardiac death in a 30-year-old preg- Intramedullary spinal cord abscess, 41 (11): Suppression of herpes simplex virus during nant woman, 41 (2):37—41 (CR) 44-47 (CR) pregnancy, 41 (4):19-22 (CRA) Graeber CW Jitendranath L Lin S Acute renal failure following intravenous Work-up of fever of unknown origin in adult Hemodynamic monitoring: review ques- immunoglobulin therapy, 41 (3):29-32 patients, 41(11):9-15 (CRA) tions, 41 (4):23-24 (SAQ) (CR) Review questions: work-up of fever of un- Lindquist LA Grate I Jr known origin in adult patients, 41 (11):28, Acute confusion in an independent, A 55-year-old man with chest pain, 41 (11): 41 (RQ) community-dwelling elderly woman, 17-20 (CPE) Johnson BE 41(8):33-38, 44 (GR) Haag BL Diplopia after otitis media: osteomyelitis of Mangrulkar RS Thyrotoxicosis, 41 (3):46—56 (CRA) the petrous temporal bone, 41 (3):33-36 Applying evidence to decisions about col- Harrison SA (CR) orectal cancer screening: how to use a Antiviral therapy for the management of clinical practice guideline, 41 (6):45-56 JohnsonJ K hepatitis C, 41 (2):31-36 (CRA) A case-based approach to teaching practice- (SMP) HaymanJ L Manku K based learning and improvement on the Intramedullary spinal cord abscess, 41 (11): The changing face of Lyme disease—rural wards, 41 (12):34—44 (SMP) 44-47 (CR) to urban, 41(1):20-24 (CR) Josephson ME Haymore BR Marchand WR Evaluation of pseudo-infarction ECG pat- Hypertriglyceridemia, 41 (3):17-24 (CRA) Evaluation and treatment of generalized tern, 41(2):14 (LE) Heilman RL anxiety disorder: review questions, 41 (7): Karnath BM Metabolic acidosis, 41 (3):37—42 (CRA) 27-28 (SAQ) Heisler M Approach to the patient with lymphadenop- Evaluation and treatment of obsessive- Helping your patients with chronic disease: athy, 41 (7):29-33 (RCS) compulsive disorder: review questions, effective physician approaches to support Easy bruising and bleeding in the adult pa- 41 (3):27-28 (SAQ) self-management, 41 (8):45-56 (SMP) tient: a sign of underlying disease, 41 (1): Neurobiology of mood disorders, 41 (9): Hemady N 35-39 (RCS) 17-26, 43 (CRA) The changing face of Lyme disease—rural Pruritus: a sign of underlying disease, 41 (10): Review questions: neurobiology of mood to urban, 41(1):20-—24 (CR) 25-29 (RCS) disorders, 41 (9):36, 43 (RQ) Neurocysticercosis: an unusual cause of Signs of dermatomyositis, 41 (4):41—44 (RCS) Marinella MA epileptic seizures, 41 (1):40-—44 (CR) Kaushik AP Clostridium difficile colitis: review questions, HoballahJ J Evaluation and management of the hand 41 (7):25-26 (SAQ) Preoperative cardiac evaluation of noncar- and wrist: review questions, 41(10):15-16 Markova T diac surgical patients: review questions, (SAQ) Abdominal aortic aneurysm in a patient with 41 (1):25-26 (SAQ) Kawji AS systemic lupus erythematosus, 41 (12): Howell G A 55-year-old man with chest pain, 41 (11): 29-32 (CR) Hydropneumothorax caused by inadvertent 17-20 (CPE) Martin P placement of a Dobhoff tube, 41 (11): Klimkowski WJ My youngest patient ever, 41 (3):32 (CB) 39-41 (CR) Abdominal aortic aneurysm in a patient with McCarthyJ J Humphrey HJ systemic lupus erythematosus, 41 (12): Hematuria and abdominal pain in a 60-year- Approach to routine interactions with indus- 29-32 (CR) old woman, 41(10):31—35 (CR) try: a primer for residents, 41 (10):47-55 Kross K McDonald GP (SMP) Enterococcus faecalis: an unusual case of tho- Awake and aware, 41(5):12 (CB) Hyun CB Mehta V racic empyema, 41 (9):49—51 (CR) Periampullary Dieulafoy’s lesion, 41 (8):23-27 KunzJ S A code close to home, 41(4):16 (CB) (CR) Acquired factor VIII deficiency treated with Metchick LN Itani KMF Thyrotoxicosis, 41 (3):46-56 (CRA) porcine factor VIII infusion followed by Surgical site infections: review questions, Mirza MA cyclophosphamide, 41 (5):44—47 (CR) 41 (12):25-26 (SAQ) Enterococcus faecalis. an unusual case of tho- Kwaku KF Jacobsen E racic empyema, 41 (9):49-51 (CR) Evaluation of pseudo-infarction ECG pat- Non-Hodgkin’s lymphoma: review ques- MitchellJ E tions, 41 (11):23-24 (SAQ) LatSearnl, l4eJ1R ( 2):14 (LE) Identifying and treating patients at high risk Jacofsky DJ for heart failure, 41 (5):27—35 (CRA) Management of type 2 diabetes: focus on Osteoarthritis, 41 (7):17-24, 42, (CRA) Moore AF Review questions: osteoarthritis, 41 (7):34, 52 the thiazolidinediones, 41 (10):37—42, 46 Asymmetric ST-segment elevations in menin- (RQ) (CRA) gococcal meningitis, 41 (11):25-27 (CR) Lee CY JarvisJ L Morgan EB Jr Signs of dermatomyositis, 41 (4):41-—44 (RCS) Antiviral therapy for the management of A clipped response, 41 (4):64 (CB) Jean-Baptiste E hepatitis C, 41 (2):31-36 (CRA) Moudgal V Management of hemoptysis in the emer- Levandoski LA Tropical and travel medicine: review ques- gency department, 41 (1):53-59 (CRA) Medication errors involving “L insulins,” tions, 41 (12):27—28 (SAQ) Jensen CR 41(6):19-22, 40 (CRA) Nee M Neurobiology of mood disorders, 41 (9): Review questions: medication errors involv- Enterococcus faecalis. an unusual case of tho- 17-26, 43 (CRA) ing “L insulins,” 41 (6):39-40, 44 (RQ) racic empyema, 41 (9):49-51 (CR) Review questions: neurobiology of mood Levsky ME NeherJ O disorders, 41 (9):36, 43 (RQ) We don’t admit dead people, 41 (2):49 (CB) Perspective, 41 (7):43 (CB) 46 Hospital Physician December 2005 www.turner-white.com 2005 Index Nguyen DD Quisling Schoene RB Hematuria and abdominal pain in a 60-year- Diplopia after otitis media: osteomyelitis of Sudden cardiac death in a 30-year-old preg- old woman, 41(10):31-—35 (CR) the petrous temporal bone, 41 (3):33-36 nant woman, 4i (2):37—41 (CR) Nguyen-Oghalai TU (CR) Schoeneman MJ Signs of dermatomyositis, 41 (4):41—44 (RCS) Rambaldini G Severe hypertension in an adolescent girl, Nielsen C Finding current best evidence in the care of a $1(9):27-32 (PR) ECG interpretation and digoxin toxicity, patient with possible pulmonary embolism: Schwartz DA 41(9):10 (LE) how to use evidence resources, 41 (2): Inflammatory bowel disease: diagnostic and A 93-year-old woman with an abnormal elec- 50-60 (SMP) treatment options, 41(12):11-19 (CRA) Nogthrroceayr dBiJo gram, 41 (6):23-25, 40 (CPE) Rifkin BS Inflammatory bowel disease: diagnostic and Analgesic therapy in patients with chronic treatment options, 41 (12):33, 44 (RQ) Severe hypertension in an adolescent girl, kidney disease: a case-based approach, Seifeldin RR $1 (9):27-32 (PR) $1 (5):13-22, 43 (CRA) The changing face of Lyme disease—rural Norris RE Review questions: analgesic therapy in pa- to urban, 41(1):20-24 (CR) Basic principles of informed consent in the tients with chronic kidney disease: a case- Neurocysticercosis: an unusual cause of acute care setting, 41 (4):45—52 (SMP) based approach, 41 (5):36, 47 (RQ) epileptic seizures, 41(1):40-—44 (CR) Oliver TG e Rist KE Shah MK Hypertriglyceridemia, 41 (3):17-—24 (CRA) Cardiac resynchronization therapy for treat- An unusual case of orbital metastasis from OropelloJM ment of congestive heart failure, 41 (1): adenocarcinoma of prostate, 41 (6):41-—43 Hemodynamic monitoring: review questions, 15-17, 24 (SA) (CR) $1 (4):23-24 (SAQ) Ross AF Shah NA Palazzo EG Preoperative cardiac evaluation of noncar- Right ventricular thrombus mimicking a myx- Sudden cardiac death in a 30-year-old preg- diac surgical patients: review questions, oma in a 19-year-old man, 41 (8):39-—42, nant woman, 41 (2):37—41 (CR) #1 (1):25-26 (SAQ) 56 (CR) Paris K Roy A Shah SMA Food allergies in children: review questions, Acute renal failure following intravenous im- Perioperative use of f-blocker therapy in 41(11):21-22 (SAQ) munoglobulin therapy, 41 (3):29-32 (CR) patients undergoing noncardiac surgery, ParksJ R Shen FH $1 (8):19-22 (CRA) Hypertriglyceridemia, 41 (3):17-24 (CRA) Evaluation and management of the hand Review questions: perioperative use of Pasquariello PS and wrist: review questions, 41 (10):15-16 B-blocker therapy in patients undergoing Headache and forehead swelling in a 9-year- (SAQ) noncardiac surgery, 41(8):27, 43—44 (RQ) old boy with sinusitis, 41 (2):43-49 (PR) Low back pain: review questions, 41 (1):27-28 Roychoudhury P A 3-month-old girl with a persistent cough (SAQ) Abdominal aortic aneurysm in a patient with and respiratory distress, 41 (7):35-—42 (PR) Sports-related nerve injuries: review questions, systemic lupus erythematosus, 41 (12): Severe hypertension in an adolescent girl, #1 (5):25-26 (SAO) 29-32 (CR) $1 (9):27-32 (PR) Shepherd B Ryan LM PattonJ N Inflammatory bowel disease: diagnostic and Acute abdomen in a patient with systemic Perioperative use of B-blocker therapy in treatment options, 41 (12):11-19 (CRA) lupus erythematosus, 41 (4):27—31 (CR) patients undergoing noncardiac surgery, Inflammatory bowel disease: diagnostic and 41(8):19-22 (CRA) Saini SD treatment options, 41 (12):33, 44 (RQ) Applying evidence to decisions about col- Review questions: perioperative use of Shishehbor MH orectal cancer screening: how to use a B-blocker therapy in patients undergoing Mechanical complications of acute myocar- clinical practice guideline, 41 (6):45-—56 noncardiac surgery, 41 (8):27, 43-44 (RQ) dial infarction: review questions, 41(5 ): Perazella MA (SMP) 23-24 (SAQ) Analgesic therapy in patients with chronic Sarin S Shriver RL kidney disease: a case-based approach, Enterococcus faecalis. an unusual case of tho- Diagnosis of pleural effusions: review ques- 41 (5):13-22, 43 (CRA) racic empyema, 41 (9):49—51 (CR) tions, 41 (9):47—48 (SAQ) Review questions: analgesic therapy in pa- Savoy ML Hydropneumothorax caused by inadvertent tients with chronic kidney disease: a case- \ 3anonth-old girl with a persistent cough placement of a Dobhoff tube, 41(11): based approach, 41 (5):36, 47 (RQ) and respiratory distress, 41 (7):35—42 (PR) 39-41 (CR) Strategies to prevent radiocontrast nephrop- Schleiss MR SlimJ athy, 41(11):29-38 (CRA) Headache and forehead swelling in a 9-year- Age prevalence of HPV infection in HIV- PieringW F old boy with sinusitis, 41 (2):43-49 (PR) negative men who have sex with men, Acute abdomen in a patient with systemic Schneider John A #1 (2):15 (IDU) lupus erythematosus, 41 (4):27—31 (CR) Approach to routine interactions with indus- Antibiotic prophylaxis in neutropenic Pinto S try: a primer for residents, 41 (10):47—55 patients, 41(8):17 (IDU) Neurocysticercosis: an unusual cause of (SMP) Anubiotic use and resistance in European epileptic seizures, 41 (1):40—44 (CR) Schneider Jonathan A outpatients, 41(5):10 (IDU) Podrazik PM Metastatic cancerso f unknown primary site, Antimicrobial regimens for treating acne, A case-based approach to teaching practice- 41 (4):33-40 (CRA) $1(2):15 (DU) based learning and improvement on the Schocken DD Burden of infection in long-term dialysis wards, 41 (12):34—44 (SMP) Shock with jugular venous distention, 41 (10): patients, 41 (2):15 (IDU) Pukkila-Worley R 17-24, 29 (CRA) Changing antimicrobial resistance to Siepto- Asymmetric ST-segment elevations in menin- Review questions: shock with jugular venous coccus pneumoniae in the United States, gococcal meningitis, 41 (11):25-27 (CR) distention, 41 (10):36, 56 (RQ) $1(10):11 (IDU) www.turner-white.com Hospital Physician December 2005 47 , 2005 Index Clonality of Staphylococcus aureus nasal car- Review questions: work-up of fever of un- WengerJ riage, 41(4):18 (IDU) known origin in adult patients, 41 (11):28, The warmth of human arms, 41 (6):28 (CB) Combined pegylated interferon alfa—2b and 41 (RQ) Weston C lamivudine for HBeAG-positive chronic Rifaximin for prevention of travelers’ diar- Atypical presentation of hepatocellular car- hepatitis B, 41(3):15 (IDU) rhea, 41(7):13 (IDU) cinoma, 41 (9):33—35, 52 (CR) Dexamethasone for the treatment of tuber- The role of human metapneumovirus infec- Whelan CT culous meningitis, 41(1):6 (IDU) tion in acute asthma exacerbations in A case-based approach to teaching practice- Echinacea for treatment of the common adults, 41(12):9 (IDU) based learning and improvement on the cold, 41(5):10 (IDU) Safety and immunogenicity of group A Strep- wards, 41(12):34—44 (SMP) Effect of antiseptic-coated catheters on tococcus vaccine in healthy adult volun- Williams PJ catheter-related infections, 41(12):9 (IDU) teers, 41(12):9 (IDU) Acquired factor VIII deficienry treated with Effect of BCG vaccination on tuberculin Sexual transmission of human T-lymphotropic porcine factor VIII infusion followed by skin test reaction, 41 (3):15 (IDU) virus | and 2, 41(7):13 (IDU) cyclophosphamide, 41 (5):44—47 (CR) Effect of daily microbiological surveillance Work-up of fever of unknown origin in adult Wolff LH Il as an infection control measure for MRSA patients, 4] (11):9-15 (CRA) Osteoarthritis, 41 (7):17-24, 42, (CRA) Smith LW in the MICU, 41(4):18 (IDU) Review questions: osteoarthritis, 41 (7):34, 52 Effect of handwashing on children’s health, Unpredicted outcomes, 41 (3):14 (CB) (RQ) Sorensen RU 41(10):11 (IDU) ZonderJ A Effect of initial drug resistance on outcomes Food allergies in children: review questions, Chronic myelogenous leukemia and other 41(11):21-22 (SAQ) in tuberculosis patients receiving short- myeloproliferative disorders: review ques- Spinn MP Efftiecramcy cohfe HmoAtAhReTra pfyo,r r4e1d(u1c):i6n g (IhDetUe)r osexu- DxRay: a 70-year-old man with an abdomi- tions, 41 (8):31-—32 (SAQ) al HIV transmission, 41 (11):7 (IDU) nal mass, 41 (1):29-34 (CPE) SUBJECT Spitalnic S Hepatitis A testing and vaccination in pa- tients with chronic liver disease due to Eye emergencies: review questions, 41 (2): Acid-base disorders hepatitis C infection, 41(11):7 (IDU) 27-28 (SAQ) Metabolic acidosis, 41 (3):37—42 (CRA) High-dose azithromycin more effective for Risk assessment I: relative risk and absolute Acquired factor VIII deficiency Group A streptococcal tonsillopharyngi- risk reduction, 41 (10):43-—46 (PLI) Acquired factor VIII deficiency treated with tis, 41(8):17 (IDU) Vascular emergencies: review questions, porcine factor VIII infusion followed by 41(10):13-14 (SAQ) Impact of varicella vaccination on varicella cyclophosphamide, 41 (5):44—47 (CR) Stein RS Allergy and immunology and herpes zoster incidence, 41 (9):16 (IDU) Anemias of bone marrow failure, 41 (2):19-26 Food allergies in children: review questions, (CRA) 41(11):21-22 (SAQ) Incidence of hepatitis A with route vaccina- Straus SE Anemia Novteilo n PoCRf chialsdsarye nr,a pi4d1l(y9 )i:d1e6nt if(iIeDsU )m ethicillin- Finding current best evidence in the care of a Anemias of bone marrow failure, 41 (2):19-26 patient with possible pulmonary embolism: (CRA) resistant Staphylococcus aureus infection, 41 (6):16 (IDU) how to use evidence resources, 41 (2): Aneurysm 50-60 (SMP) Outcome of HIV-associated tuberculosis in Sunkureddi P Abdominal aortic aneurysm in a patient with the era of HAART, 41(1):6 (IDU) Signs of dermatomyositis, 41 (4):41-44 (RCS) systemic lupus erythematosus, 41 (12): Pneumococcal vaccination for elderly per- 29-32 (CR) Tandyopadhyay T sons in Spain, 41(7):13 (IDU) Antiphospholipid antibodies Poor outcome with metronidazole for TMeawya rhie Ar est in peace, 41(11):16 (CB) Right ventricular thrombus mimicking a Clostridium difficile colitis, 41(8):17 (IDU) Robotic laparoscopic radical prostatectomy, myxoma in a 19-year-old man, 41 (8): Population-based assessment of macrolide 41(9):37-43 (SA) 39-42, 56 (CR) resistance of Streptococcus pneumoniae Thompson PW Autoimmune disease before and after vaccine introduction, Sports-related nerve injuries: review ques- Signs of dermatomyositis, 41 (4):41-44 (RCS) 41(5):10 (IDU) Thyrotoxicosis, 41 (3):46—56 (CRA) tions, 41 (5):25-26 (SAQ) Prevalence of and risk factors for fluoro- Underwood D B-Blockers quinolone-resistant Neisseria gonorrhoeae, A 93-year-old woman with an abnormal elec- Perioperative use of B-blocker therapy in pa- 41(11):7 (IDU) trocardiogram, 41 (6):23-25, 40 (CPE) tients undergoing noncardiac surgery, Prevalence of methicillin-resistant Staphylo- Ural SH 41(8):19-22 (CRA) coccus aureus, 41(9):16 (IDU) Review questions: suppression of herpes sim- Review questions: perioperative use of Preventing nosocomial bloodstream infec- plex virus during pregnancy, 41 (4):32, 64 B-blocker therapy in patients undergoing tion in critically ill neonates with central (RQ) noncardiac surgery, 41 (8):27, 43-44 (RQ) venous catheters, 41(10):11 (IDU) Rhesus alloimmunization: review questions, Bleeding Purpura fulminans due to Staphylococcus 41(6):37-38 (SAQ) Easy bruising and bleeding in the adult pa- aureus, 41(6):16 (IDU) Suppression of herpes simplex virus during tient: a sign of underlying disease, 41 (1): Rapid progression to AIDS in a patient with pregnancy, 41 (4):19-22 (CRA) 35-39 (RCS) multidrug-resistant, dual-tropic HIV-1, Vasudev M Hematuria and abdominal pain in a 41(6):16 (IDU) Acute abdomen in a patient with systemic 60-year-old woman, 41 (10):31-35 (CR) Reducing nosocomial MRSA infection in lupus erythematosus, 41 (4):27—31 (CR) Management of hemoptysis in the emer- the ICU, 41(4):18 (IDU) Weisman DS gency department, 41(1):53-59 (CRA) Reliability of tuberculin skin test readings, A 55-year-old woman with unilateral facial Periampullary Dieulafoy’s lesion, 41(8): 41(3):15 (IDU) paralysis and pain, 41 (3):43-—45 (CPE) 23-27 (CR) 48 Hospital Physician December 2005 www.turner-white.com 2005 Index Boerhaave’s syndrome My youngest patient ever, 41(3):32 clinical practice guideline, 41 (6):45-56 A 55-year-old man with chest pain, 41 (11): Perspective, 41 (7):43 (SMP) 17-20 (CPE) A slight resemblance, 41(8):18 Finding current best evidence in the care of a Cancer Unpredicted outcomes, 41 (3):14 patient with possible pulmonary embolism: Atypical presentation of hepatocellular car- The warmth of human arms, 41 (6):28 how to use evidence resources, 41 (2): cinoma, 41 (9):33—35, 52 (CR) We don’t admit dead people, 41 (2):49 50-60 (SMP) DxRay: a 70-year-old man with an abdomi- Communication Fever of unknown origin nal mass, 41 (1):29-34 (CPE) Helping your patients with chronic disease: Review questions: work-up of fever of un- Metastatic cancers of unknown primary site, effective physician approaches to support known origin in adult patients, 41 (11):28, 41(4):33-40 (CRA) selfmanagement, 41 (8):45-—56 (SMP) 41 (RQ) Non-Hodgkin’s lymphoma: review questions, Critical care medicine Work-up of fever of unknown origin in adult 41(11):23-24 (SAQ) Hemodynamic monitoring: review questions, patients, 41(11):9-15 (CRA) Robotic laparoscopic radical prostatectomy, 41(4):23-24 (SAQ) Gastroenterology 41(9):37—43 (SA) Deep vein thrombosis DxRay: a 70-year-old man with an abdomi- An unusual case of orbital metastasis from Upper extremity deep vein thrombosis, 41 nal mass, 41 (1):29-34 (CPE) adenocarcinoma of prostate, 41 (6):41-—43 (6):29-34 (CRA) Gastrointestinal and liver disease during (CR) Dermatologic conditions pregnancy: review questions, 41 (2):29-—30 Cardiac disease Pruritus: a sign of underlying disease, 41 (10): (SAQ) Cardiac resynchronization therapy for treat- 25-29 (RCS) Hematuria and ahdominal pain in a 60-year- ment of congestive heart failure, 41 (1): Signs of dermatomyositis, 41 (4):41—44 (RCS) old woman, 41 (:9):31—35 (CR) 15-17, 24 (SA) A 54-year-old man with fever, skin rash, and Inflammatory bowel disease: diagnostic and Identifying and treating patients at high risk oral ulcers, 41 (12):22-—24, 32 (CPE) treatment options, 41 (12):11-19 (CRA) for heart failure, 41 (5):27—35 (CRA) Diabetes mellitus Inflammatory bowel disease: diagnostic and Review questions: shock with jugular venous Management of type 2 diabetes: focus on treatment options, 41 (12):33, 44 (RQ) distention, 41 (10):36, 56 (RQ) the thiazolidinediones, 41 (10):37—42, 46 Malabsorption and vitamin deficiencies due Right ventricular thrombus mimicking a myx- (CRA) to gastrointestinal illness: review questions, oma in a 19-year-old man, 41 (8):39-42, Medication errors involving “L insulins,” 41(6):35-36 (SAQ) 56 (CR) 41(6):19-22, 40 (CRA) Pediatric gastroenterology: review questions, Shock with jugular venous distention, 41 (10): Review questions: medication errors involv- $1 (9):45-46 (SAQ) 17-24, 29 (CRA) ing “L insulins,” 41(6):39-—40, 44 (RQ) Periampullary Dieulafoy's lesion, 41 (8): Sudden cardiac death in a 30-year-old preg- Digoxin toxicity 23-27 (CR) nant woman, 41 (2):37—41 (CR) EGG interpretation and digoxin toxicity, Geriatric Rounds A 93-year-old woman with an abnormal elec- 41(9):10 (LE) Acute confusion in an independent, trocardiogram, 41 (6):23-25, 40 (CPE) A 93-year-old woman with an abnormal elec- community-dwelling elderly woman, Cardiovascular disease trocardiogram, 41 (6):23-25, 40 (CPE) $1 (8):33-38, 44 Evaluation of pseudo-infarction ECG pat- Diverticulitis Heart failure tern, 41 (2):14 (LE) Hematuria and abdominal pain in a 60-year- Cardiac resynchronization therapy for treat- Hypertriglyceridemia, 41 (3):17-24 (CRA) old woman, 41 (10):31—35 (CR) ment of congestive heart failure, 41 (1): Mechanical complications of acute myocar- Emergency medicine 15-17, 24 (SA) dial infarction: review questions, 41 (5): Eye emergencies: review questions, 41 (2): Identifying and treating patients at high risk 23-24 (SAQ) 27-28 (SAQ) for heart failure, 41 (5):27—35 (CRA) Upper extremity deep vein thrombosis, 41 (6): Management of hemoptysis in the emer- Hematology 29-34 (CRA) gency department, 41 (1):53-59 (CRA) Acquired factor VIII deficiency treated with Clinical Practice Exam Vascular emergencies: review questions, porcine factor VIII infusion followed by DxRay: a 70-year-old man with an abdomi- 41(10):13-14 (SAQ) cyclophosphamide, 41 (5):44—47 (CR) nal mass, 41 (1):29-34 Empyema Anemias of bone marrow failure, 41 (2): A 55-year-old man with chest pain, 41 (11): Enterococcus faecalis. an unusual case of tho- 19-26 (CRA) 17-20 racic empyema, 41 (9):49-51 (CR) Chronic myelogenous leukemia and other A 54-year-old man with fever, skin rash, and Encephalomyelitis myeloproliferative disorders: review ques- oral ulcers, 41 (12):22-24, 32 Acute disseminated encephalomyelitis in a tions, 41(8):31-32 (SAQ) A 55-year-old woman with unilateral facial 4year-old girl, 41 (5):37—43 (CR) Hemoptysis paralysis and pain, 41 (3):43—45 Endocrinology Management of hemoptysis in the emer- A 93-year-old woman with an abnormal Diagnosis and treatment of pituitary gland gency department, 41 (1):53-—59 (CRA) electrocardiogram, 41 (6):23-25, 40 disorders: review questions, 41 (8):29-30 Hepatitis C virus Clinical practice guidelines (SAQ) Antiviral therapy for the management of Applying evidence to decisions about col- Management of type 2 diabetes: focus on hepatitis C, 41 (2):31—36 (CRA) orectal cancer screening: how to use a the thiazolidinediones, 41 (10):37—42, 46 Herpes simplex virus clinical practice guideline, 41 (6):45—56 (CRA) Review questions: suppression of herpes sim- (SMP) Medication errors involving “L insulins,” plex virus during pregnancy, 41 (4):32, 64 Code Blue Stories 41(6):19-22, 40 (CRA) (RQ) Awake and aware, 41 (5):12 Review questions: medication errors involv- Suppression of herpes simplex virus during A clipped response, 41 (4):64 ing “L insulins,” 41 (6):39-—40, 44 (RQ) pregnancy, 41 (4):19-22 (CRA) A code close to home, 41 (4):16 Thyrotoxicosis, 41 (3):46-—56 (CRA) Hydropneumothorax Do no harm, 41(10):30 Evidence-based medicine Hydropneumothorax caused by inadvertent A helpful clinical pearl, 41 (2):42 Applying evidence to decisions about col- placement of a Dobhoff tube, 41 (11): May he rest in peace, 41(11):16 orectal cancer screening: how to use a 39-41 (CR) www.turner-white.com Hospital Physician December 2005 49 2005 Index Hypertension Effect of daily microbiological surveillance Informed consent Severe hypertension in an adolescent girl, as an infection control measure for MRSA Basic principles of informed consent in the 41(9):27-32 (PR) in the MICU, 41(4):18 acute care setting, 41 (4):45-52 (SMP) Hypertriglyceridemia Effect of handwashing on children’s health, Job searching Hypertrigiycciidemia, 41 (3):17-24 (CRA) 41(10):11 Finding the practice that is right for you: tips Infectious diseases Effect of initial drug resistance on outcomes for a successfujlob search after residency, Antiviral therapy for the management of in tuberculosis patients receiving short- 41(4):52-63 (SMP) hepatitis C, 41 (2):31-36 (CRA) term chemotherapy, 41 (1):6 Jugular venous distention Asymmetric ST-segment elevations in menin- Efficacy of HAART for reducing heterosexu- Review questions: shock with jugular venous gococcal meningitis, 41 (11):25-27 (CR) al HIV transmission, 41 (11):7 distention, 41 (10):36, 56 (RQ) The changing face of Lyme disease—rural Hepatitis A testing and vaccination in patients Shock with jugular venous distention, 41 (10): to urban, 41 (1):20-24 (CR) with chronic liver disease due to hepatitis C 17-24, 29 (CRA) Clostridium difficile colitis: review questions, infection, 41 (11):7 Kidney disease 41(7):25-26 (SAQ) High-dose azithromycin more effective for Acute renal failure following intravenous Enterococcus faecalis. an unusual case of tho- Group A streptococcal tonsillopharyngi- immunoglobulin therapy, 41 (3):29-32 racic empyema, 41 (9):49-51 (CR) tis, 41(8):17 (CR) Analgesic therapy in patients with chronic Hospital epidemiology and infection con- Impact of varicella vaccination on varicella trol: review questions, 41 (3):25-26 (SAQ) and herpes zoster incidence, 41 (9):16 kidney disease: a case-based approach, 41(5):13-22, 43 (CRA) Intramedullary spinal cord abscess, 41 (11): Incidence of hepatitis A with route vaccina- Review questions: analgesic therapy in pa- Neu4r4o-c4ys7t ic(eCrRc)o sis: an unusual cause of epi- Novteilo n PoCRf chaislsdary enr,a pi4d1l(y9 )i:d1e6nt ifies methicillin- btiaesnetds waiptphr ocahcrho,n ic 41 k(i5d)n:3e6y, d4i7s ea(sReQ: ) a case- leptic seizures, 41 (1):40—44 (CR) r4e1s(is6t)a:n1t6 Staphylococcus aureus infection, Strategies to prevent radiocontrast nephropa- Pertussis, 41 (7):44—52 (CRA) Outcome of HIV-associated tuberculosis in thy, 41 (11):29-38 (CRA) Review questions: suppression of herpes sim- Liver disease the era of HAART, 41(1):6 plex virus during pregnancy, 41 (4):32, 64 Pneumococcal vaccination for elderly per- Antiviral therapy for the management of (RQ) hepatitisC , 41 (2):31—36 (CRA) Suppression of herpes simplex virus during sons in Spain, 41(7):13 Lyme disease Poor outcome with metronidazole for pregnancy, 41 (4):19-22 (CRA) The changing face of Lyme disease—rural Clostridium difficile colitis, 41 (8):17 Surgical site infections: review questions, to urban, 41 (1):20-24 (CR) Population-based assessment of macrolide 41(12):25-26 (SAQ) Lymphadenopathy resistance of Streptococcus pneumoniae Tropical and travel medicine: review ques- Approach to the patient with lymphadenopa- before and after vaccine introduction, tions, 41 (12):27-28 (SAQ) thy, 41(7):29-33 (RCS) 41(5):10 A vegetarian with neurocysticercosis, 41 (3):2 Medication safety Prevalence of and risk factors for fluoro- (LE) Medication errors involving “L insulins,” A 55-year-old woman with unilateral facial quinolone-resistant Neisseria gonorrhoeae, 41(6):19-22, 40 (CRA) 41(11):7 paralysis and pain, 41 (3):43-—45 (CPE) Review questions: medication errors involv- Prevalence of methicillin-resistant Staphylo- Infectious Diseases Update \abstracts] ing “L insulins,” 41(6):39-40, 44 (RQ) Age prevalence of HPV infection in HIV- coccus aureus, 41 (9):16 Meningitis Preventing nosocomial bloodstream infec- negative men who have sex with men, Asymmetric ST-segment elevations in menin- tion in critically ill neonates with central 41(2):15 gococcal meningitis, 41 (11):25-27 (CR) Antibiotic prophylaxis in neutropenic pa- venous catheters, 41(10):11 Metabolic acidosis Purpura fulminans due to Staphylococcus tients, 41(8):17 Metabolic acidosis, 41 (3):37—42 (CRA) Antibiotic use and resistance in European aureus, 41(6):16 Milk-alkali syndrome outpatients, 41 (5):10 Rapid progression to AIDS in a patient with Acute confusion in an independent, multidrug-resistant, dual-tropic HIV-1, community-dwelling elderly woman, Antimicrobial regimens for treating acne, $1(6):16 41 (8):33-38, 44 (GR) 41(2):15 Reducing nosocomial MRSA infection in Neurocysticercosis Burden of infection in long-term dialysis the ICU, 41(4):18 Neurocysticercosis: an unusual cause of patients, 41(2):15 Reliability of tuberculin skin test readings, epileptic seizures, 41 (1):40-—44 (CR) Changing antimicrobial resistance to Strepto- $1(3):15 A vegetarian with neurocysticercosis, 41 (3):2 coccus pneumoniae in the United States, Rifaximin for prevention of travelers’ diar- (LE) 41(10):11 rhea, 41(7):13 Neurology Clonality of Staphylococcus aureus nasal car- The role of human metapneumovirus infec- Differential diagnosis of common demen- riage, 41(4):18 tion in acute asthma exacerbations in tias: review questions, 41 (4):25-26 (SAQ) Combined pegylated interferon alfa—2b and adults, 41(12):9 Orthopaedic sports medicine lamivudine for HBeAG-positive chronic Safety and immunogenicity of group A Strep- Sports-related nerve injuries: review ques- hepatitis B, 41(3):15 lococcus vaccine in healthy adult volun- tions, 41 (5):25-26 (SAQ) Dexamethasone for the treatment of tuber- teers, 41(12):9 Osteoarthritis culous meningitis, 41 (1):6 Sexual transmission of human T-lymphotropic Osteoarthritis, 41 (7):17-24, 42, (CRA) Echinacea for treatment of the common virus | and 2, 41(7):13 Review questions: osteoarthritis, 41 (7):34, 52 cold, 41(5):10 Inflammatory bowel disease (RQ) Effect of antiseptic-coated catheters on Inflammatory bowel disease: diagnostic and Otitis media catheter-related infections, 41(12):9 treatment options, 41 (12):11-19 (CRA) Diplopia after otitis media: osteomyelitis of Effect of BCG vaccination on tuberculin Inflammatory bowel disease: diagnostic and the petrous temporal bone, 41 (3):33-36 skin test reaction, 41(3):15 treatment options, 41 (12):33, 44 (RQ) (CR) 50 Hospital Physician December 2005 www.turner-white.com 2005 Indéx Pain management Pulmonary disease Combunox, 41(1):14 Analgesic therapy in patients with chronic Diagnosis of pleural effusions: review ques- Enablex, 41(2):18 kidney disease: a case-based approach, tions, 41 (9):47—48 (SAQ) Exjade, 41(12):10 41(5):13-22, 43 (CRA) Enterococcus faecalis: an unusual case of tho- Humira, 41(11):8 Review questions: analgesic therapy in pa- racic empyema, 41 (9):49-51 (CR) Levemir, 41(8):16 tients with chronic kidney disease: a case- Hydropneumothorax caused by inadvertent Lipitor, 41(11):8 based approach, 41 (5):36, 47 (RQ) placement of a Dobhoff tube, 41 (11): Macugen, 41 (2):18 Palliative care 39-41 (CR) Merrem IV, 41 (7):16 A survey of hospice and palliative care part 2: Radiocontrast nephropathy Mycamine, 41 (5):11 therapeutic interventions, 41 (1):45—52, 60 Strategies to prevent radiocontrast nephropa- Nasonex, 41(2):18 thy, 41(11):29-38 (CRA) (CRA) Nexium IV, 41(6):11 Patient self-management Review of Clinical Signs Pegasys and Copegus, 41 (4):17 Approach to the patient with lymphadenopa- Helping your patients with chronic disease: Prialt, 41(3):16 thy, 41 (7):29-33 effective physician approaches to support Proquad, 41:(10):12 Easy bruising and bleeding in the adult selfmanagement, 41 (8):45—56 (SMP) Requip, 41 (7):16 patient: a sign of underlying disease, Pediatric Rounds Revatio, 41 (7):16 $1 (1):35-39 Headache and forehead swelling in a 9-year- Rozerem, 41(9):13 Pruritus: a sign of underlying disease, old boy with sinusitis, 41 (2):43-—49 Symlin, 41(5):11 #1 (10):25-29 \ 3-month-old girl with a persistent cough Synera, 41(9):13 Signs of dermatomyositis, 41 (4):41-—44 and respiratory distress, 41 (7):35—42 Tygacil, 41(8):16 Review Questions Severe hypertension in an adolescent girl, Inflammatory bowel disease: diagnostic and Tysabri, 41 (1):14 $1 (9):27-32 treatment options, 41 (12):33, 44 Ventavis, 41(3):16 Pertussis Review questions: analgesic therapy in VESIcare, 41(1):14 Pertussis, 41 (7):44—52 (CRA) patients with chronic kidney disease: a Self-Assessment Questions Practice-based learning and improvement case-based approach, 41 (5):36, 47 Chronic myelogenous leukemia and other A case-based approach to teaching practice- Review questions: medication errors involv- myeloproliferative disorders: review ques- based learning and improvement on the ing “L insulins,” 41 (6):39-—40, 44 tions, 41(8):31-32 wards, 41 (12):34-—44 (SMP) Review questions: neurobiology of mood Clostridium difficile colitis: review questions, Pregnancy disorders, 41 (9):36, 43 #1 (7):25-26 Gastrointestinal and liver disease during Review questions: osteoarthritis, 41 (7):34, 52 Diagnosis and treatment of pituitary gland pregnancy: review questions, 41 (2):29-30 Review questions: perioperative use of disorders: review questions, 41 (8):29-30 (SAQ) B-blocker therapy in patients undergoing Diagnosis of pleural effusions: review ques- Review questions: suppression of herpes sim- noncardiac surgery, 41 (8):27, 43-44 tions, 41 (9):47—48 plex virus during pregnancy, 41 (4):32, 64 Review questions: shock with jugular venous Differential diagnosis of common demen- (RQ) distention, 41 (10):36, 56 tias: review questions, 41 (4):25-26 Rhesus alloimmunization: review questions, Review questions: suppression of herpes sim- Evaluation and management of the hand 41 (6):37-38 (SAQ) plex virus during pregnancy, 41 (4):32, 64 and wrist: review questions, 41(10):15-16 Suppression of herpes simplex virus during Review questions: work-up of fever of un- Evaluation and treatment of generalized pregnancy, 41 (4):19-22 (CRA) known origin in adult patients, 41 (11):28, anxiety disorder: review questions, 4(17 ): Primer in Literature Interpretation 1] 27-28 Risk assessment I: relative risk and absolute Rheumatologic conditions Evaluation and treatment of obsessive- risk reduction, 41 (10):43—46 Ihe changing face of Lyme disease—rural compulsive disorder: review questions, Professionalism to urban, 41(1):20-24 (CR) $1 (3):27-28 Approach to routine interactions with indus- Osteoarthritis, 41 (7):17-24, 42, (CRA) Eye emergencies: review questions, 41 (2): Review questions: osteoarthritis, 41 (7):34, 52 try: a primer for residents, 41 (10):47—55 27-28 (RQ) (SMP) Food allergies in children: review questions, Severe hypertension in an adolescent girl, Basic principles of informed consent in the 11(11):21-22 $1 (9):27—32 (PR) acute care setting, 41 (4):45-—52 (SMP) Gastrointestinal and liver disease during Risk assessment Pruritus pregnancy: review questions, 41 (2):29-30 Risk assessment I: relative risk and absolute Pruritus: a sign of underlying disease, 41 (10): Hemodynamic monitoring: review ques- risk reduction, 41 (10):43-—46 (PLI) 25-29 (RCS) Rx Update tions, 41 (4):23-24 Psychiatry Hospital epidemiology and infection control: Abraxane, 41(3):16 Differential diagnosis of common demen- ACTOplus met, 41:(10):12 review questions, 41 (3):25-26 lias: review questions, 41 (4):25-26 (SAQ) Aptivus, 41 (8):16 Low back pain: review questions, 41 (1):27-28 Evaluation and treatment of generalized Aromasin, 41(11):8 Malabsorption and vitamin deficiencies due anxiety disorder: review questions, 41 (7): Arranon, 41 (12):10 to gastrointestinal illness: review questions, 27-28 (SAQ) Asmanex Twisthaler, 41(5):11 $1 (6):35-36 Evaluation and treatment of obsessive- Atacand, 41(4):17 Mechanical complications of acute myocar- compulsive disorder: review questions, BiDil, 41(9):13 dial infarction: review questions, 41 (5): 41 (3):27-28 (SAQ) Boostrix, 41(6):11 23-24 Neurobiology of mood disorders, 41 (9): Byetta, 41(6):11 Non-Hodgkin's lymphoma: review questions, 17-26, 43 (CRA) Celebrex, 41:(10):12 $1(11):23-24 Review questions: neurobiology of mood Claritin-D 24 Hour, 41 (4):17 Pediatric gastroenterology: review questions, disorders, 41(9):36, 43 (RQ) Clobex Spray, 41(12):10 $1 (9):45-—46 www.turner-white.com Hospital Physician December 2005 51 and 0.0; rash 1.4a nd 7.1; oral monili0.a9s anid s4. 0;f ev0.5e anrd 3 .0; pruriattun son -application site Creatinine (mg/dL) 0.4 and 0.0 respectively. The percent of pediatric patients witha t least one 0.0 and 2.0; and anaphylaxis 0.0 ve 10.1" respectively. La Changes ZYVOX has been substantially abnormal serum chemistry value in patients treated with ZYVOX or vancomycin for any associated with thrombocytopenia when used in doses up to and including 600 mg every 12 hours other indication’ were as follows: ALT (U/L 10.1 and 12.5; amylase (U/U 0.6 and 1.3; total bilirubin for up to 28 days. In Phase 3 comparator-controlled trials, the percentage of adult patients who (mg/d6.L3) an d 5.2; and creatinine (mg/dU 2.4 and 1.0 respectively. Postmarketing Experience developed a substantially low platelet count (defined as less than 75% of lower limit of normal and/or Myelosuppression (including anemia, leukopenia, pancytopenia, and Seosnecacenas has been baseline) was 2.4% (range among studies: 0.3 to 10.0%) with ZYVOX and 1.5% (range among studies: reported during postmarketing use of ZYVOX (see WARNINGS). Peripheral neuropathy, and optic 0.4 to 7.0%) with a comparator. In a study of a pediatric patients ranging in age from birth through 11 years, the percentage of patients who developed a substantially low platelet count (defined as less than 75% of lower limit of normal and/or baseline) was 12.9% with ZYVOX and 13.4% reports have primarily been in patients treated for longer than the maximum recommended with vancomycin. In an poy ae studyo f pediatric patients aged from 5 through 17 years, the duration of 28 days, Se ee ee eee eee percentage of patients who developed a substantially low platelet count was 0% with ZYVOX and therapy. Serotonin syndromhea s been reported in patients receiving concomitant 0.4% with cefadroxil. Thrombocytopenia associated with the use of ZYVOX appears to be dependent agents and ZYVOX (see PRECAUTIONS). These events have been chosen for inclusion due to either on duration of therapy, + gotane greater than 2 weeks of treatment). The platelet counfotr smos t their seriousness, frequency of reporting, possible causal connection to ZYVOX, or a combination of patients retumed to the normal range/baseline during the follow-up period. No related clinical these factors. Because they are reported voluntarily from a population of unknown size, estimates adverse events were identified in Phase 3 clinical trials in patients developing thrombocytopenia. of frequency cannot be made and causal relationship cannot be precisely established. Bleeding events were identified in thrombocytopenic patients in a compassionate use program for In the event of supportive care is advised, with maintenance of ZYVOX; the role of linezolid in these events cannot be determined (see WARNINGS). Changes seen in glomerular filtration. Hemodialysis may facilitate more rapid elimination of linezolid. in a Phase 1 other laboratory parameters, without regard to drug relationship, revealed no substantial differences Clinical trial, approximately 30% of a dose of linezolid was removed during a 3-hour hemodialysis between ZYVOX and the comparators. These changes were generally not clinically significant, did not session beginning 3 hours after the dose of linezolid was administered. Data are not available for lead to discontinuoaft thieoranpy , and were reversible. The percent of adult patients wiatth lea st removal of linezolid with peritoneal dialysis or hemoperfusion. Clinical signs of acute toxicity in one substantially abnormal hematologic” value in patients treated with ZYVOX 400 mg q12h or animals were decreased activity and ataxia in rats and vomiting and tremors in dogs treated with 3000 Clarithromycin 250 mg q12h for uncomplicated skin and skin structure infections were as follows: mg/kg/day and 2000 mg/kg/day, respectively. hemoglobin (g/dL) 0.9 and 0.0; platelet count (x 108/mm+*) 0.7 and 0.8; WBC (x 10°/mm) 0.2 and 0.6; * MDRSP refers to isolates resistant to 2 or more of the following antibiotics: penicillin, second- neutrophils (x 108/mm®*) 0.0 and 0.2 respectivelyT.h e percent of adult patients with at least one neration conhdospamns, macrolides, tetracycline, and ns ag ye substantially abnormal hematologic” value in patients treated with ZYVOX 600 mg 12h or a ¢ Crparators ind cefpodoxime ‘proxetil 200 mg POq 12h; ceftriaxone 1 g IV q12h; comparator’ were as follows: hemoglobin (g/dL 7.1 and 6.6; platelet count (x 10°/mm*) 3.0 and 1.8; eee 250 mg PO q12h; dicloxacillin 500 mg PO a pad 2 9 IV q6h; vancomycin WBC (x 10°/mm*) 2.2 and 1.3 and neutrophils (x 10°/mm*) 1.1 and 1.2 respectively. The percent of 19NVq adult patients with at least one substantially abnormal serum chemistry*t value in patients treated * The most commonly reported drug-related adverse events leading to discontinuation in patients with ZYVOX 400 mg q12h or clarithromycin 250 mg q12h for uncomplicated skin and skin structure treated with ZYVOX were nausea, headache, diarrhea, and vomiting infections were as follows: AST (U/L) 1.7 and 1.3; ALT (U/L) 1.7 and 1.7; LDH (U/L 0.2 and 0.2; alkaline § Comparators included cefpodoxime proxetil 200 mg PO q12h; ceftriaxone 1 g IV q12h; dicloxacillin phosphatase (U/L 0.2 and 0.2; lipase (U/L) 2.8 and 2.6; amylase (U/L) 0.2 and 0.2; total bilirubin (mg/dL) 500 mg PO a6h; oxacillin 2 g IV q6h; vancomycin 1 g IV q12h. 0.2 and 0.0; BUN (mg/dL) 0.2 and 0.0; and creatinine (mg/dL 0.2 and 0.0 respectively. The percent of ' Patients 5 through 11 years of age received ZYVOX 10 mg/kg PO q12h or cefadroxil 15 ma/kg PO adult patients with at least one substantially abnormal serum chemistry‘t value in patients treated 12h, Patients 12 years or older received ZYVOX 600 mg PO q12h or cefadroxil 500 mg PO q12h. with ZYVOX 600 mg q12h or a comparatowre’r e as follows: AST (U/L) 5.0 and 6.8; ALT (U/L) 9.6 and 1 Patients from birth through 11 years of age received ZYVOX 10 mg/kg IV/PO a8h or vancomycin 9.3; LDH (U/U 1.8 ~ 1.5; alkaline phosphatase (U/L 3.5 and 3.1; lipase (U/L 4.3 and 4.2; amylase (U/L) 10 to 15 mg/kg IV q6-24h, depending on age and renal clearance. 2.4 and 2.0; total bilirubin (mg/dL) .9 and 1.1; BUN (mg/dL 2.1 and 1.5; and creatinine (mg/dL) 0.2 These reports were of ‘red-man syndrome,’ which were coded as anaphylaxis. and 0.6 res , The percento f pediatric patients with at least one substantially abnormal * <75% (<50% for neutrophils) of Lower Limit of Normal (LLN) for values normal at baseline; <75% hematologic* value in patients treated with ZYVOX or cefadroxil for uncomplicated skin and skin (<50% for neutrophils) of LLN and of baseline for values abnormal at baseline. structure infections! were as follows: hemoglobin (g/dL) 0.0 and 0.0; platelet count (x 108/mm+*)o n: *t >2 x Upper Limit of Normal (ULN) for values normal at baseline; >2 x ULN and >2 x baseline for and 0.4; WBC (x 108/mm+*) 0.8 and 0.8; neutrophils (x 10°/mm*) 1.2 and 0.8 respectively. The per values abnormal at baseline. of pediatric patients with at least one substantially abnormal hematologic** value in patients rab * <75% (<50% for neutrophils) of Lower Limit of Normal (LLN) for values normal at baseline; <75% with ZYVOX or vancomycin for any other indication’ were as follows: hemoglobin (g/dL 15.7 and (<50% for neutrophils) of LLN and <75% (<50% for neutrophils, <90% for hemoglobin if baseline 12.4; platelet count (x 10°/mm*) 12.9 and 13.4; WBC (x 108/mm*) 12.4 and 10.3 and neutrophils (x <LLN) of baseline for values abnormal at baseline. 10°/mmi) 5.9 and 4.3 respectively. The percent of pediatric patients with at least one substantially # >2 x Upper Limit of Normal (ULN) for values normal at baseline; >2 x ULN and >2 (>1.5 for total abnormal serum chemistry value in patients treated with ZYVOX or cefadroxil for uncomplicated skin bilirubin) x baseline for values abnormal at baseline. and skin structure infections! were as follows: ALT (U/L) 0.0 and 0.0; lipase (U/U 0.4 and 1.2; and Rx only Rev. May 2005 ZV236405 © 2005 Pfizer Inc. All rights reserved. CD U.S, Pharmaceuticals 2005 Index Preoperative cardiac evaluation of noncar- Helping your patients with chronic disease: f-blocker therapy in patients undergoing diac surgical patients: review questions, effective physician approaches to support noncardiac surgery, 41 (8):27, 43-44 (RQ) 41(1):25-26 selfmanage ment, 41(8):45-56 Robotic laparoscopic radical prostatectomy, Rhesus alloimmunization: review questions, Shock 41(9):37—43 (SA) 41(6):37-38 Review questions: shock with jugular venous Surgical site infections: review questions, Sports-related nerve injuries: review ques- distention, 41 (10):36, 56 (RQ) 41 (12):25-26 (SAQ) tions, 41 (5):25-26 Shock with jugular venous distention, Surgical site infections: review questions, 41(10):17-24, 29 (CRA) Systemic lupus erythematosus 41 (12):25-26 Sinusitis, complications of Acute abdomen in a patient with systemic Tropical and travel medicine: review ques- Headache and forehead swelling in a 9-year- lupus erythematosus, 41 (4):27—31 (CR) tions, 41 (12):27-28 old boy with sinusitis, 41 (2):43-—49 (PR) Abdominal aortic aneurysm in a patient with ee emergencies: review questions, Spinal cord abscess systemic lupus erythematosus, 41 (12): 41(10):13-14 Intramedullary spinal cord abscess, 41 (11): 29-32 (CR) Seminars in Medical Practice 44-47 (CR) Takayasu’s arteritis Applying evidence to decisions about col- Stevens-Johnson syndrome Severe hypertension in an adolescent girl, orectal cancer screening: how to use a A 54-year-old man with fever, skin rash, and clinical practice guideline, 41 (6):45-56 oral ulcers, 41 (12):22-—24, 32 (CPE) 41(9):27-32 (PR) Approach to routine interactions with indus- Surgery Thiazolidinediones try: a primer for residents, 41 (10):47-55 Evaluation and management of the hand Management of type 2 diabetes: focus on Basic principles of informed consent in the and wrist: review questions, 41(10):15-16 the thiazolidinediones, 41 (10):37—42, 46 acute care setting, 41 (4):45-52 (SAQ) (CRA) A case-based approach to teaching practice- Low back pain: review questions, 41 (1):27-28 Thyroid disease based learning and improvement on the (SAQ) Thyrotoxicosis, 41 (3):46-56 (CRA) wards, 41 (12):34—44 Perioperative use of B-blocker therapy in pa- Varicella zoster virus Finding current best evidence in the care of a tients undergoing noncardiac surgery, A 55-year-old woman with unilateral facial patient with possible pulmonary embolism: 41(8):19-22 (CRA) how to use evidence resources, 41 (2):50—60 Preoperative cardiac evaluation of noncar- paralysis and pain, 41 (3):43-45 (CPE) Finding the practice that is right for you: tips diac surgical patients: review questions, Vascular rings for a successfujlob search after residency, 41(1):25-26 (SAQ) A 3-month-old girl with a persistent cough 41(4):52-63 Review questions: perioperative use of and respiratory distress, 41 (7):35-—42 (PR) 52 Hospital Physician December 2005 www.turner-white.com

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