Hormone Action Part K: Neuroendocrine Peptides

940 Pages·1989·25.674 MB·English

by  P. Michael Conn (Eds.)

Contributors to Volume 168
Article numbers are in parentheses following the names of contributors.
Affiliations listed are current.
S. AGRAWAL (54), Medical Research Coun- ROBERT C. BAXTER (20), Department of -nE
cil (MRC), Laboratory of Molecular Biol- docrinology, Royal Prince Alfred Hospi-
ogy, Cambridge 2BC 2QH, England tal, Camperdown, New South Wales,
M. C. AGUILA (51), Department of Physiol- Australia 2050
ogy, Neuropeptide Division, ehT Univer- MARGERY C. BEINFELD (1), Department of
• sity of Texas Southwestern Medical Cen- Pharmacology, St. Louis University Med-
ter at Dallas, Dallas, Texas 53257 ical School, St. Louis, Missouri 40136
WILFRIED ALLAERTS (5), Laboratory of lleC NIRA BEN-JONATHAN (9, 15), Department
Pharmacology, University of Leuven, of Physiology and Biophysics, Indiana
School of Medicine, B-3000 Leuven, University, School of Medicine, Indian-
Belgium apolis, Indiana 32264
ROBERTA ALLEN (32), Autonomic Physiol- M. BERG (35), Protein Chemistry, Rorer
ogy Laboratory, Department of Medi- Biotechnology Inc., Rockville, Maryland
cine, University of California, San Diego, 05802
Medical Center, San Diego, California THOMAS A. BICSAK (31), Department of Re-
30129 productive Medicine, University of -ilaC
P. C. ANDREWS (6), Department of Bio- fornia, San Diego, La Jolla, California
chemistry, Purdue University, West La- 39029
fayette, Indiana 47907 A. E. BISHOP (57), Department of Histo-
H. ARAI (54), Department of Psychophar- chemistry, Royal Postgraduate Medical
macology, "cirtaihcysP Research Institute School, University of London, Hammer-
of Tokyo, Setagaya-ku, Tokyo 156, Japan smith Hospital, London WI2 0NN, -nE
WILLIAM McD. ARMSTRONt~ (9), Depart- gland
ment of Physiology and Biophysics, Indi- J. EDWIN BLALOCK (3), Department of
ana University, School of Medicine, Indi- Physiology and Biophysics, ehT Univer-
anapolis, Indiana 32264 sity of Alabama at Birmingham, Birming-
FRANr BAEDINO, JR. (55), Cephalon, Inc., ham, Alabama 49253
West Chester, Pennsylvania 08391 M. BLUM (43), Fishberg Research Center
WILLIAM A. BANKS (45), Veterans Adminis- for Neurobiology, ehT Mount Sinai
tration, Medical Center, and Tulane Uni- Medical Center, New York, New York
versity School of Medicine, New Orleans, 92001
Louisiana 64107 KENNETH L. BOST (3), Department of Phys-
C. WAYNE BARDIN (42), ehT Population iology and Biophysics, ehT University of
Council, Center for Biomedical Research, Alabama at Birmingham, Birmingham,
New York, New York 12001 Alabama 49253
AYALLA BARNEA (50), Departments of -bO THOMAS BROCK (24), Departments of Medi-
stetrics and Gynecology and of Physiol- cine and Pharmacology, ehT Neurobiol-
ogy, ehT University of Texas Southwest- ogy Curriculum and the Biological Sci-
nre Medical Center at Dallas, Dallas, ences Research Center, ehT University of
Texas 53257 North Carolina at Chapel Hill, School of
xi
xii CONTRIBUTORS TO VOLUME 168
Medicine, Chapel Hill, North Carolina tics Branch, National Institutes of
99572 Health, Bethesda, Maryland 29802
ELAINE R. BROWN (44), Department of P. MICHAEL CONN (18), Department of
Anatomy and Neurobiology, Washington Pharmacology, The University of Iowa,
University School of Medicine, St. Louis, College of Medicine, Iowa City, Iowa
Missouri 01136 24225
NIVRAM R. BROWN (32), Autonomic Physi- ANNE Z. NAGIRROC (42), The Clayton Foun-
ology Laboratory, Departments of Medi- dation Laboratories for Peptide Biology,
cine and Surgery, University of Califor- The Salk Institute, La Jolla, California
nia, San Diego, Medical Center, San 73029
Diego, California 30129 DAVID W. CRABB (48), Departments of
Medicine and Biochemistry, Indiana Uni-
J. PETER H. HCABRUB (28, 29), Rudolf Mag-
versity, School of Medicine, Indianapolis,
nus Institute for Pharmacology, Medical
Indiana 32264
Faculty, University of Utrecht, 3521 GD
Utrecht, The Netherlands JEAN D. SNIMERC (44), Department of Anat-
omy and Neurobiology, Washington Uni-
JOHN C. CAMBIER (22), Department of Pedi-
versity School of Medicine, St. Louis,
atrics, National Jewish Center for Immu-
Missouri 01136
nology and Respiratory Medicine, Den-
ver, Colorado 60208 SAMOHT L. CROXTON (9), Department of
Physiology and Biophysics, Indiana Uni-
NYLORAC A. CAMPEN (42), ehT Clayton
versity, School of Medicine, Indianapolis,
Foundation Laboratories for Peptide Bi-
Indiana 32264
ology, ehT Salk Institute, La Jolla, Cali-
MICHAEL D. CULLER (37), Reproductive
fornia 73029
Neuroendocrinology Section, Laboratory
PETER CARMELIET (5), Laboratory of Cell of Molecular and Integrative Neuro-
Pharmacology, University of Leuven,
science, National Institute of Environ-
School of Medicine, B-3000 Leuven,
mental Health Sciences, National Insti-
Belgium
tutes of Health, Research Triangle Park,
MARK S. CARTER (44), Department of Anat- North Carolina 90772
omy and Neurobiology, Washington Uni- KRISTINE D. DAnE (30), Veterans Adminis-
versity School of Medicine, St. Louis, tration, Medical Center, Seattle, Wash-
Missouri 01136
ington 80189
ESIOCNARF-EIRAM TELESSEHC (55), Depart- CARL DENEF (5), Laboratory of Cell Phar-
ment of Pharmacology, The Medical Col- macology, University of Leuven, School
lege of Pennsylvania, Philadelphia, Penn- of Medicine, B-3000 Leuven, Belgium
sylvania 92191
TREBOR A. SlANRAHSED (59), Laboratory of
MILLIE M. CHIEN (22), Department of Pedi- Populations, ehT Rockefeller University,
atrics, National Jewish Center for Immu- New York, New York 12001
nology and Respiratory Medicine, Den- KCAJ E. DIXON (6, 48), Department of Bio-
ver, Colorado 60208
chemistry, Purdue University, West La-
C. UOLUODOTSIRHC (54), Medical Research fayette, Indiana 47907
Council (MRC), Laboratory of Molecular SELRAHC H. NOSREME (26, 40), Department
Biology, Cambridge 2BC 2QH, England of Medicine, Division of Endocrinology,
ELBIB M. CHRONWALL (56), Division of University of Massachusetts, School of
Structural and Systems Biology, Kansas Medicine, Worcester, Massachusetts
City School of Basic Life Sciences, Uni- 55610
versity of Missouri, Kansas City, Mis- P. C. EMSON (54), Medical Research Coun-
souri 64801, and Experimental Therapeu- cil ( MRC) Group, Agricultural and Food
CONTRIBUTORS TO VOLUME 168 xiii
Research Council (A.F.R.C.), Institute of NORAA J. W. HSUEH (30, 31), Department
Animal Physiology and Genetics Re- of Reproductive Medicine, University of
search (I.A.P.G.R.), Babraham, Cam- California, San Diego, La Jolla, Califor-
bridge 2BC 4AT, England nia 39029
JOHN ENG (19), Solomon A. Berson Re- JANE HUMM (24, 25), Departments of Medi-
search Laboratory, Veterans Administra- cine and Pharmacology, ehT Neurobiol-
tion, Medical Center, Bronx, New York ogy Curriculum and the Biological Sci-
,86401 and Mount Sinai School of Medi- ences Research Center, ehT University of
cine, City University of New York North Carolina at Chapel Hill, School of
(CUNY), New York, New York 92001 Medicine, Chapel Hill, North Carolina
LAUREL A. FISHER (32), Department of 99572
Pharmacology, The University of Ari- W. C. HYMER (21), Department of Molecu-
zona, College of Medicine, Tucson, Ari- lar and Cell Biology, Paul M. Althouse
zona 42758 Laboratory, ehT Pennsylvania State Uni-
GARY FISKUM (35), Department of Bio- versity, University Park, Pennsylvania
chemistry, The George Washington Uni- 20861
versity School of Medicine and Health XIAO-CHI JIA (30), Department of Repro-
Sciences, Washington, D.C. 20037 ductive Medicine, University of Califor-
EDWARD D. FRENCH (7), Department of nia, San Diego, La Jolla, California 39029
Pharmacology, The University of Ari- DIANE JOLEEY (42), ehT Clayton Founda-
zona, College of Medicine, Tucson, Ari- tion Laboratories for Peptide Biology,
zona 42758 ehT Salk Institute, La Jolla, California
M. J. GAIT (54), Medical Research Council 73O29
(MRC), Laboratory of Molecular Biol- ABBA J. KASTIN (45), Veterans Administra-
ogy, Cambridge 2BC 2QH, England tion, Medical Center, and Tulane Univer-
MARVIN C. NROGNEHSREG (13), Depart- sity School of Medicine, New Orleans,
ment of Medicine, Division of Endocrinol- Louisiana 64107
ogy and Metabolism, Cornell University HCEICJOW IKSREIZDEK (27), Department of
Medical College, New York, New York Obstetrics and Gynecology, ehT Univer-
12001 sity of Texas Southwestern Medical Cen-
MICHEL GOEDERT (34), Medical Research ter at Dallas, Dallas, Texas 53257
Council (MRC), Laboratory of Molecular AICRAM E. KENDALL (21), Department of
Biology, Cambridge 2BC 2QH, England Molecular and Cell Biology, Paul M.
HECTOR A. GONZALEZ (27), Servicio de AIthouse Laboratory, ehT Pennsylvania
Dermatologia, Hospital Clinico de al State University, University Park, Penn-
Universidad de Chile, Santos Dumont sylvania 20861
,999 Santiago, Chile KEITH M. KENDRICK (11), Department of
ELI HAZUM (36, 52), Department of Bio- Behavioural Physiology, Agricultural
chemistry, Glaxo Research Laboratories, Food and Research Council (A.F.R.C.),
Research Triangle Park, North Carolina Institute of Animal Physiology and Genet-
90772 ics Research (I.A.P.G.R.), Babraham,
Cambridge 2BC 4AT, England
ALRAC M. HEKMAN (31), Department of Ba-
sic and Clinical Research, Scripps Clinic USHIO KIKKAWA (23), Department of Bio-
and Research Foundation, La Jolla, Cali- chemistry, Kobe University School of
fornia 73029 Medicine, Kobe 650, Japan
KLAUS NNAMREH (39), Dermatology Clinic, JOHN S. KIZER (24, 25), Departments of
University of Munich, Munich, Federal Medicine and Pharmacology, ehT Neuro-
Republic of Germany biology Curriculum and the Biological
xiv CONTRIBUTORS TO VOLUME 168
Sciences Research Center, ehT Univer- BIN LIU (28), Rudolf Magnus Institute for
sity of North Carolina at Chapel Hill, Pharmacology, Medical Faculty, Univer-
School of Medicine, Chapel Hill, North sity of Utrecht, 3521 GD Utrecht, ehT
Carolina 99572 Netherlands
JEANNE B. KOGER (25), Departments of RETLAW C. LOW (15), Department of Physi-
Medicine and Pharmacology, The Neuro- ology and Biophysics, Indiana University,
biology Curriculum and the Biological School of Medicine, Indianapolis, Indi-
Sciences Research Center, ehT Univer- ana 32264
sity of North Carolina at Chapel Hill, CRAIG A. MCARDLE (18), Institute for Hor-
School of Medicine, Chapel Hill, North mone and Fertility Research (IHF),
Carolina 99572 0002-D Hamburg ,45 Federal Republic of
JAMES E. KRAUSE (44), Department of Germany
Anatomy and Neurobiology, Washington JOSEPH T. MCCABE (59), Laboratory of
University School of Medicine, St. Louis, Neurobiology and Behavior, ehT Rocke-
Missouri 01136 feller University, New York, New York
HPLODUR G. KRAUSE II (58), Medical Prod- 12001
ucts Department, E. .1 ud Pont de Ne- S. M. MCCANN (51), Department of Physi-
mours & Company, Incorporated, Experi- ology, Neuropeptide Division, ehT Uni-
mental Station Laboratory, Wilmington, versity of Texas Southwestern Medical
Delaware 89891 Center at Dallas, Dallas, Texas 53257
DRAHCIR M. KRIS (35), Protein Chemistry, DRAHCIR KCOTN1LCCM (42), ehT Clayton
Rorer Biotechnology Inc., Rockville, Foundation Laboratories for Peptide Bi-
Maryland 05802 ology, ehT Salk Institute, La Julia, Cali-
fornia 73029
EDMUND F. LAGAMMA (47), Department of
Pediatrics and Department of Neurobiol- TERAGRAM R. MACDONALD (44), Depart-
ogy and Behavior, State University of ment of Anatomy and Neurobiology,
New York (SUNY) at Stony Brook, Stony Washington University School of Medi-
Brook, New York 49711 cine, St. Louis, Missouri 01136
ECNERWAL H. SURAZAL (33), Laboratory of PHILIPPE SNETREAM (5), Laboratory of Cell
Pharmacology, University of Leuven,
Molecular and Integrative Neuroscience,
School of Medicine, B-3000 Leuven,
Peptide Neurochemistry Group, National
Belgium
Institute of Environmental Health Sci-
ences, National Institutes of Health, Re- SAMOHT F. J. MARTIN (14), Department of
search Triangle Park, North Carolina Zoology, ehT University of Wisconsin,
90772 Madison, Wisconsin 60735
DENIS A. LEONG (17), Departments of In- OLAZNOG MARTfNEZ ED AL ARELACSE (16),
ternal Medicine and Neuroscience, Uni- Instituto de lnvestigaciones Biomddicas,
versity of Virginia Medical Center, Universidad Naeional Aut6noma de M~x-
Charlottesville, Virginia 80922 ico, 04510, Mexico DF., Mexico
NOJ E. LEVINE (10), Department of Neuro- ANNICK MIGNON (5), Laboratory of Cell
biology and Physiology, Northwestern Pharmacology, University of Leuven,
University, Evanston, Illinois 80206 School of Medicine, B-3000 Leuven,
LEAHCIM E. LEWIS (55, 56, 58), Cephalon, Belgium
Inc., West Chester, Pennsylvania 08391 NYLORAC D. MINTH (48), Department of
LORAC D. LINDEN (35), Department of Bio- Biochemistry, Purdue University, West
chemistry, The George Washington Uni- Lafayette, Indiana 47907
versity School of Medicine and Health YRRET W. MOODY (35), Department of Bio-
Sciences, Washington, D.C. 20037 chemistry, ehT George Washington Uni-
CONTRIBUTORS TO VOLUME 168 XV
versity School of Medicine and Health nre Medical Center at Dallas, Dallas,
Sciences, Washington, D.C. 20037 Texas 53257
ORIHCI MURAl (15), Department of Physiol- KEITH D. POWELL (10), Department of
ogy and Biophysics, Indiana University, Neurobiology and Physiology, North-
School of Medicine, Indianapolis, Indi- western University, Evanston, Illinois
ana 32264 80206
S~IRDNA NEGRO-VILAR (37, 38), Reproduc- MOHAN K. RAIZADA (39), Department of
tive Neuroendocrinology Section, Labo- Physiology, University of Florida, Col-
ratory of Molecular and Integrative lege of Medicine, Gainesville, Florida
Neuroscience, National Institute of Envi- 01623
ronmental Health Sciences, National In- DENNIS D. NESSUMSAR (12), Department of
stitutes of Health, Research Triangle Reproductive Medicine, University of
Park, North Carolina 90772 California, San Diego, La JoUa, Califor-
NOMIS NEUBORT (41), Neurology Research nia 39029
Center, State of New York, Department HPESOJ R. REEVE, JR. (46), Department of
of Health, Helen Hayes Hospital, West Medicine, UCLA School of Medicine,
Haverstraw, New York 39901 University of California, Los Angeles,
IMOTUSAY NISHIZUKA (23), Department of Los Angeles, California 42009
Biochemistry, Kobe University School of ENIREHTAC RIVIER (42), ehT Clayton Foun-
Medicine, Kobe 650, Japan dation Laboratories for Peptide Biology,
SAMOHT L. O'DONOHUE t (1), Central Ner- ehT Salk Institute, La Jolla, California
vous System Disease Research, Mon- 73O29
santo-G. D. Searle and Company, St. JEAN RIVIER (42), ehT Clayton Foundation
Louis, Missouri 89136 Laboratories for Peptide Biology, ehT
KouJl OGITA (23), Department of Biochem- Salk Institute, La Jolla, California 73029
istry, Kobe University School of Medi- WIM THCEREBBOR (5), Laboratory of Cell
cine, Kobe 650, Japan Pharmacology, University of Leuven,
DRAHNIER A. KICVOLAP (8), Department of School of Medicine, B-3000 Leuven, Bel-
Neuroscience, University of Florida, Col- gium
lege of Medicine, Gainesville, Florida
WADE T. SREGOR (58), Engineering Physics
01623
Laboratory, E. .1 du Pont ed Nemours &
DONALD W. PFAFF (59), Laboratory of Company, Incorporated, Experimental
Neurobiology and Behavior, ehT Rocke- Station Laboratory, Wilmington, Dela-
feller University, New York, New York ware 89891
12001
HPESOJ REGNISSELHCS (35), Rorer Biotech-
M. NAI PHILLIPS (8, 39), Department of nology Inc., Rockville, Maryland 05802
Physiology, University of Florida, Col-
SEMAJ S. SCHWABER (56, 58), Medical
lege of Medicine, Gainesville, Florida
Products Department, E. I. du Pont ed
01623
Nemours & Company, Incorporated, Ex-
J. M. POLAK (57), Department of Histo- perimental Station Laboratory, Wil-
chemistry, Royal Postgraduate Medical
mington, Delaware 89891
School, University of London, Hammer-
JEFFREY ZTRAWHCS (4), Medical Research
smith Hospital, London 21W ONN, En-
Centre, Prince Henry's Hospital, Mel-
gland
bourne, Australia 4003
JOHN C. PORTER (27), Departments of -bO
NYLORAC D. SCOTT (20), Department of En-
stetrics and Gynecology and of Physiol-
docrinology, Royal Prince Alfred Hospi-
ogy, ehT University of Texas Southwest-
tal, Camperdown, New South Wales,
Deceased. Australia 2050
xvi CONTRIBUTORS OT VOLUME 168
MARK S. SHEARMAN (23), Department of iology, National Yang-Ming Medical Col-
Biochemistry, Kobe University School of lege, Shih-Pai, Taipei, Taiwan ,12111
Medicine, Kobe 650, Japan Republic of China
KAREN C. SWEARINGEN (16), Department DRAHCIR I. WEINER (16), Department of
of Biology, Mills College, Oakland, Cali- Obstetrics, Gynecology and Reproductive
fornia 31649 Sciences, School of Medicine, University
of California, San Francisco, San Fran-
Luc SWENNEN (5), Laboratory of Cell
cisco, California 34149
Pharmacology, University of Leuven,
School of Medicine, B-3000 Leuven, Bel- W. WETSEL (38), Reproductive Neuroendo-
gium crinology Section, Laboratory of Molecu-
lar and Integrative Neuroscience, Na-
SEMAJ P. TAM (2), The Rockefeller Univer-
tional Institute of Environmental Health
sity, New York, New York 12001
Sciences, National Institutes of Health,
EGROEG R. UHL (53), Gene Neuroscience
Research Triangle Park, North Carolina
Unit and Departments of Neurology and
90772
Neuroscience, Addiction Research Cen-
ter, National Institute on Drug Abuse and JEFFREY D. WHITE (47), Division of Endo-
crinology, Department of Medicine and
ehT Johns Hopkins School of Medicine,
Department of Neurobiology and Behav-
Baltimore, Maryland 42212
ior, State University of New York (SUNY)
WYLIE VALE (4, 42), ehT Clayton Founda-
at Stony Brook, Stony Brook, New York
tion Laboratories for Peptide Biology,
49711
The Salk Institute, La Jolla, California
73O29 JOHN T. WILLIAMS (7), Institute for Ad-
vanced Biomedical Research, The Ore-
GuY ETTEUQILAV (41), Department of Med-
gon Health Sciences University, Port-
icine, State of New York, Department of
land, Oregon 10279
Health, Helen Hayes Hospital, West
WILLIAM E. WILSON (33), Laboratory of
Haverstraw, New York 10993, and De-
Molecular and Integrative Neuroscience,
partment of Neurology, College of Physi-
Peptide Neurochemistry Group, National
cians and Surgeons of Columbia Univer-
Institute of Environmental Health Sci-
sity, New York, New York 23001
ences, National Institutes of Health, Re-
HUBERT H. M. VAN TOE (29), Rudolf Mag-
search Triangle Park, North Carolina
nus Institute for Pharmacology, Medical
90772
Faculty, University of Utrecht, 3521 GD
IRENE WINICOV (13), Department of Medi-
Utrecht, The Netherlands
cine, Division of Endocrinology and Me-
JOAN M. VAUGHAN (42), The Clayton Foun- tabolism, Cornell University Medical -loC
dation Laboratories for Peptide Biology,
lege, New York, New York 12001
The Salk Institute, La Jolla, California
NYLASOR S. YALOW (19), Solomon A. Ber-
73O29
son Research Laboratory, Veterans Ad-
JOSEF K. RYAMLGOV (42), Division of Re- ministration, Medical Center, Bronx,
productive Biology, Florida Institute of New York ,86401 and Mount Sinai School
Technology, Melbourne, Florida 10923
of Medicine, City University of New York
JOHN H. WALSH (46), Department of Medi- (CUNY), New York, New York 92001
cine, UCLA School of Medicine, Univer- W. SCOTT YOUNG III (49), Laboratory of
sity of California, Los Angeles, Los Cell Biology, National Institute of Mental
Angeles, California 42009 Health, National Institutes of Health, Be-
SULUAP S. WANG (27), Department of Phys- thesda, Maryland 29802
Preface
This volume supplements Volumes 301 and 421 of Methods ni Enzy-
mology, which also deal with neuroendocrine peptides, and is consider-
ably less archival than its predecessors. In many cases the methods pre-
sented include shortcuts and conveniences not included in the sources
from which they were taken. The techniques are described in a context
that allows comparisons to other related methodologies. The authors have
been encouraged to do this in the belief that such comparisons are valu-
able to readers who must adapt extant procedures to new systems. Also,
so far as possible, methodologies have been presented in a manner that
stresses their general applicability and potential limitations. Special atten-
tion has been paid to statistics and means of data analysis and assessment.
Although some topics for various reasons are not covered, the three
volumes dealing with neuroendocrine peptides provide a substantial and
current overview of the extant methodology in the field and a view of its
rapid development.
This volume does not include a cross-index since the recent, preceding
volumes included comprehensive indexes. Since publication of Volume
124, most ancillary information is contained in Methods in Enzymology
Volumes 139 Cellular Regulators (Part A: Calcium- and Calmodulin-
Binding Proteins) and 141 Cellular Regulators (Part B: Calcium and
Lipids).
Particular thanks go to the authors for their attention to meeting dead-
lines and for maintaining high standards of quality, to the series editors for
their encouragement, and to the staff of Academic Press for their help and
timely publication of the volume.
P. MICHAEL CONN
iivx
METHODS IN ENZYMOLOGY
EMULOV I. Preparation and Assay of Enzymes
Edited by YENDIS P. KCIWOLOC DNA NAHTAN O. NALPAK
EMULOV II. Preparation and Assay of Enzymes
Edited by SIDNEY P. KClWOLOC DNA NAHTAN O. NALPAK
EMULOV III. Preparation and Assay of Substrates
Edited by YENDIS P. KCIWOLOC DNA NAHTAN O. NALPAK
EMULOV IV. Special Techniques for the Enzymologist
Edited by YENDIS P. KCIWOLOC DNA NAHTAN O. NALPAK
EMULOV V. Preparation and Assay of Enzymes
Edited by SIDNEY P. KC1WOLOC DNA NAHTAN O. NALPAK
EMULOV VI. Preparation and Assay of Enzymes (Continued)
Preparation and Assay of Substrates
Special Techniques
Edited by YENDIS P. KCIWOLOC DNA NAHTAN O. NALPAK
EMULOV VII. Cumulative Subject Index
Edited yb SIDNEY P. KCIWOLOC DNA NAHTAN O. NALPAK
EMULOV VIII. Complex Carbohydrates
Edited yb ELIZABETH F. NEUFELD DNA ROTCIV GRUBSNIG
EMULOV IX. Carbohydrate Metabolism
Edited by WILLIS A. DOOW
EMULOV X. Oxidation and Phosphorylation
Edited by DLANOR W. KOORBATSE DNA DRANYAM E. NAMLLUP
EMULOV XI. Enzyme Structure
Edited by C. H. W. HIRS
EMULOV XII. Nucleic Acids (Parts A and B)
Edited by ECNERWAL NAMSSORG DNA KlVlE EVADLOM
xix
XX SDOHTEM NI YGOLOMYZNE
EMULOV XIII. Citric Acid Cycle
Edited by J. M. NIETSNEWOL
VOLUME XIV. Lipids
Edited by J. M. NIETSNEWOL
EMULOV XV. Steroids and Terpenoids
Edited by RAYMOND B. CLAYTON
VOLUME XVI. Fast Reactions
Edited by HTENNEK NITSUK
EMULOV XVII. Metabolism of Amino Acids and Amines (Parts A and B)
Edited by HERBERT TABOR AND CELIA WHITE TABOR
EMULOV XVIII. Vitamins and Coenzymes (Parts A, B, and C)
Edited by DONALD I. MCCORMICK AND LEMUEL D. WRIGHT
VOLUME XIX. Proteolytic Enzymes
Edited by GERTRUDE E. PERLMANN AND LASZLO LORAND
EMULOV XX. Nucleic Acids and Protein Synthesis (Part C)
Edited by KIVIE MOLDAVE AND LAWRENCE GROSSMAN
EMULOV XXI. Nucleic Acids (Part D)
Edited by ECNERWAL NAMSSORG DNA KIVIE MOLDAVE
EMULOV XXII. Enzyme Purification and Related Techniques
Edited by WILLIAM I. JAKOBY
EMULOV XXIII. Photosynthesis (Part A)
Edited by ANTHONY SAN PIETRO
EMULOV XXIV. Photosynthesis and Nitrogen Fixation (Part B)
Edited by ANTHONY SAN PIETRO
EMULOV XXV. Enzyme Structure (Part B)
Edited by C. H. W. HIRS DNA EGRES N. EFEHSAMIT
EMULOV XXVI. Enzyme Structure (Part C)
Edited by C. H. W. HIRS DNA EGRES N. EFEHSAMIT
METHODS IN ENZYMOLOGY xxi
EMULOV XXVII. Enzyme Structure (Part D)
Edited by C. H. W. HIRS DNA EGRES N. FFEHSAMIT
EMULOV XXVIII. Complex Carbohydrates (Part B)
Edited by ROTCIV GRUBSNIG
EMULOV XXIX. Nucleic Acids and Protein Synthesis (Part E)
Edited by ECNERWAL NAMSSORG DNA KIVIE EVADLOM
EMULOV XXX. Nucleic Acids and Protein Synthesis (Part F)
Edited by KIVIE EVADLOM DNA ECNERWAL NAMSSORG
EMULOV XXXI. Biomembranes (Part A)
Edited by SIDNEY REHCSIELF DNA LESTER REKCAP
EMULOV XXXII. Biomembranes (Part B)
Edited by YENDIS REHCSIELF DNA RETSEL REKCAP
EMULOV XXXIII. Cumulative Subject Index Volumes I-XXX
Edited by AHTRAM G. DENNIS DNA DRAWDE A. SINNED
EMULOV XXXIV. Affinity Techniques (Enzyme Purification: Part B)
Edited by WILLIAM B. YBOKAJ DNA MElR KEHCLIW
EMULOV XXXV. Lipids (Part )B
Edited by JOHN M. NIETSNEWOL
EMULOV XXXVI. Hormone Action (Part A: Steroid Hormones)
Edited by BERT W. O'MALLEY DNA JOEL G. NAMDRAH
EMULOV XXXVII. Hormone Action (Part B: Peptide Hormones)
Edited by BERT W. O'MALLEY DNA JOEL G. NAMDRAH
EMULOV XXXVIII. Hormone Action (Part C: Cyclic Nucleotides)
Edited by JOEL G. NAMDRAH DNA BERT W. O'MALLEY
EMULOV XXXIX. Hormone Action (Part D: Isolated Cells, Tissues, and
Organ Systems)
Edited by JOEL G. NAMDRAH DNA BERT W. O'MALLEY
EMULOV XL. Hormone Action (Part E: Nuclear Structure and Function)
Edited by BERT W. O'MALLEY DNA JOEL G. NAMDRAH