Evidence-Based Complementary and Alternative Medicine High-Tech Acupuncture and Integrative Laser Medicine 2013 Guest Editors: Gerhard Litscher, Xin-Yan Gao, Lu Wang, and Bing Zhu High-Tech Acupuncture and Integrative Laser Medicine 2013 Evidence-Based Complementary and Alternative Medicine High-Tech Acupuncture and Integrative Laser Medicine 2013 Guest Editors: Gerhard Litscher, Xin-Yan Gao, Lu Wang, and Bing Zhu Copyright©2013HindawiPublishingCorporation.Allrightsreserved. Thisisaspecialissuepublishedin“Evidence-BasedComplementaryandAlternativeMedicine.”Allarticlesareopenaccessarticles distributedundertheCreativeCommonsAttributionLicense,whichpermitsunrestricteduse,distribution,andreproductioninany medium,providedtheoriginalworkisproperlycited. Editorial Board TerjeAlraek,Norway AnwarulH.Gilani,Pakistan AndreasMichalsen,Germany ShrikantAnant,USA MichaelGoldstein,USA DavidMischoulon,USA SedighehAsgary,Iran SveinHaavik,Norway Hyung-InMoon,RepublicofKorea HyunsuBae,RepublicofKorea Seung-HeonHong,Korea AlbertMoraska,USA LijunBai,China MarkusHorneber,Germany MarkMoss,UK SarangBani,India Ching-LiangHsieh,Taiwan MinKyunNa,RepublicofKorea VassyaBankova,Bulgaria BennyT.K.Huat,Singapore RichardL.Nahin,USA WinfriedBanzer,Germany RomanHuber,Germany VitalyNapadow,USA VernonA.Barnes,USA AngeloAntonioIzzo,Italy F.R.F.Nascimento,Brazil JairoK.Bastos,Brazil K.Jarukamjorn,Thailand IsabellaNeri,Italy SujitBasu,USA StefanieJoos,Germany T.B.Nguelefack,Cameroon DavidBaxter,NewZealand Z.Kain,USA MartinOffenbacher,Germany Andre-MichaelBeer,Germany OsamuKanauchi,Japan Ki-WanOh,RepublicofKorea AlvinJ.Beitz,USA KrishnaKaphle,Nepal Y.Ohta,Japan YongC.Boo,RepublicofKorea KenjiKawakita,Japan OlumayokunA.Olajide,UK FrancescaBorrelli,Italy JongY.Kim,RepublicofKorea ThomasOstermann,Germany GloriaBrusotti,Italy YounC.Kim,RepublicofKorea StaceyA.Page,Canada ArndtBu¨ssing,Germany C.-H.Kim,RepublicofKorea Tai-LongPan,Taiwan RaffaeleCapasso,Italy YoshiyukiKimura,Japan BhushanPatwardhan,India OpherCaspi,Israel ToshiakiKogure,Japan BeritS.Paulsen,Norway Shun-WanChan,HongKong ChingLan,Taiwan AndreaPieroni,Italy Il-MooChang,RepublicofKorea AlfredLa¨ngler,Germany RichardPietras,USA RajnishChaturvedi,India LixingLao,USA XianqinQu,Australia Tzeng-JiChen,Taiwan Jang-HernLee,RepublicofKorea CassandraL.Quave,USA YunfeiChen,China MyeongS.Lee,UK RojaRahimi,Iran KevinChen,USA TatleangLee,Singapore KhalidRahman,UK Juei-TangCheng,Taiwan ChristianLehmann,Canada CheppailRamachandran,USA EvanP.Cherniack,USA MarcoLeonti,Italy KeRen,USA Jen-HweyChiu,Taiwan Ping-ChungLeung,HongKong Mee-RaRhyu,RepublicofKorea WilliamC.S.Cho,HongKong ChunGuangLi,Australia Jose´LuisR´ıos,Spain JaeYoulCho,Korea Xiu-MinLi,USA PaoloR.diSarsina,Italy Shuang-EnChuang,Taiwan ShaoLi,China B.Saad,PalestinianAuthority EdwinL.Cooper,USA SabinaLim,Korea A.Sandner-Kiesling,Austria VincenzoDeFeo,Italy WenChuanLin,China AdairSantos,Brazil R.DelaP.Va´zquez,Spain ChristopherG.Lis,USA G.Schmeda-Hirschmann,Chile AlexandraDeters,Germany GerhardLitscher,Austria RosaSchnyer,USA MohamedEddouks,Morocco I-MinLiu,Taiwan AndrewScholey,Australia TobiasEsch,Germany KeLiu,China VeroniqueSeidel,UK YibinFeng,HongKong YijunLiu,USA SenthamilR.Selvan,USA J.Fernandez-Carnero,Spain GaofengLiu,China TuhinadriSen,India JulianoFerreira,Brazil GailB.Mahady,USA RonaldSherman,USA PeterFisher,UK SubhashC.Mandal,India KarenJ.Sherman,USA RomainForestier,France JeanineMarnewick,SouthAfrica KanShimpo,Japan JoelJ.Gagnier,Canada VirginiaS.Martino,Argentina Byung-CheulShin,Korea MuhammadN.Ghayur,Pakistan JamesH.McAuley,Australia RachidSoulimani,France MohdR.Sulaiman,Malaysia ManiVasudevan,Malaysia HarukiYamada,Japan VenilN.Sumantran,India CarloVentura,Italy NobuoYamaguchi,Japan TokuTakahashi,USA WagnerVilegas,Brazil Yong-QingYang,China RabihTalhouk,Lebanon PradeepVisen,Canada KenYasukawa,Japan CheChunTao,USA AristoVojdani,USA M.Yoon,RepublicofKorea MeiTian,China Chong-ZhiWang,USA HongQ.Zhang,HongKong YaoTong,HongKong Shu-MingWang,USA BoliZhang,China K.V.Trinh,Canada Y.Wang,USA RuixinZhang,USA VolkanTugcu,Turkey ChenchenWang,USA HongZhang,Sweden Yew-MinTzeng,Taiwan KenjiWatanabe,Japan HaiboZhu,China DawnM.Upchurch,USA W.Weidenhammer,Germany AlfredoVannacci,Italy J.M.Wilkinson,Australia Contents High-TechAcupunctureandIntegrativeLaserMedicine2013,GerhardLitscher,Xin-YanGao,LuWang, andBingZhu Volume2013,ArticleID590718,2pages ClinicalEffectofAcupunctureonEndemicSkeletalFluorosis:ARandomizedControlledTrial, ZhouJincao,WuZhongchao,ChenZhongjie,ZhaoXiaoguang,HuJing,JiaoYue,LiGuiran,andPangLi Volume2013,ArticleID839132,5pages TheInfraredRadiationTemperatureCharacteristicofAcupointsofMammaryGlandHyperplasia Patients,JuanjuanZheng,YiZhao,YafangWang,ShengfangHu,PingLu,andXueyongShen Volume2013,ArticleID567987,5pages EffectsofLowLevelLaserTherapyonOvalbumin-InducedMouseModelofAllergicRhinitis, BinhyeChoi,MunSeogChang,HaYoungKim,Jae-WooPark,BonghaRyu,andJinsungKim Volume2013,ArticleID753829,8pages Wave-InducedFlowinMeridiansDemonstratedUsingPhotoluminescentBioceramicMaterialon AcupuncturePoints,C.WillChen,Chen-JeiTai,Cheuk-SingChoy,Chau-YunHsu,Shoei-LoongLin, WingP.Chan,Han-SunChiang,Chang-AnChen,andTing-KaiLeung Volume2013,ArticleID739293,11pages EffectofLow-LevelLaserStimulationonEEGPowerinNormalSubjectswithClosedEyes,Jih-HuahWu andYang-ChyuanChang Volume2013,ArticleID476565,10pages EffectofElectroacupunctureatST36onGastric-RelatedNeuronsinSpinalDorsalHornandNucleus TractusSolitarius,XiaoyuWang,HongShi,HongyanShang,WeiHe,ShuliChen,GerhardLitscher, IngridGaischek,andXianghongJing Volume2013,ArticleID912898,6pages EffectofLaserIrradiationatDifferentWavelengths(940,808,and658nm)onPressureUlcerHealing: ResultsfromaClinicalStudy,J.Taradaj,T.Halski,M.Kucharzewski,T.Urbanek,U.Halska,andC.Kucio Volume2013,ArticleID960240,8pages IntravenousLaserBloodIrradiationIncreasesEfficacyofEtanerceptinSelectedSubtypesofJuvenile IdiopathicArthritis:AnInnovativeClinicalResearchApproach,DragosAndreiChiran, GerhardLitscher,MichaelWeber,LauraMarinelaAilioaie,ConstantinAilioaie,andDanielaLitscher Volume2013,ArticleID168134,9pages TheTimeCourseEffectsofElectroacupunctureonPromotingSkeletalMuscleRegenerationand InhibitingExcessiveFibrosisafterContusioninRabbits,RongguoWang,DanLuo,ChengXiao,PengLin, ShouyaoLiu,QianweiXu,andYuntingWang Volume2013,ArticleID869398,16pages AuricularAcupuncturewithLaser,ReginaRound,GerhardLitscher,andFrankBahr Volume2013,ArticleID984763,22pages Near-InfraredSpectroscopyforObjectifyingCerebralEffectsofLaserAcupunctureinTermand PretermNeonates,WolfgangRaith,GerhardPichler,IrisSapetschnig,AlexanderAvian, ConstanzeSommer,NariaeBaik,MartinKoestenberger,GeorgM.Schmo¨lzer,andBerndtUrlesberger Volume2013,ArticleID346852,6pages HindawiPublishingCorporation Evidence-BasedComplementaryandAlternativeMedicine Volume2013,ArticleID590718,2pages http://dx.doi.org/10.1155/2013/590718 Editorial High-Tech Acupuncture and Integrative Laser Medicine 2013 GerhardLitscher,1,2Xin-YanGao,2LuWang,1andBingZhu2 1StronachResearchUnitforComplementaryandIntegrativeLaserMedicine, ResearchUnitofBiomedicalEngineeringinAnesthesiaandIntensiveCareMedicine,TCMResearchCenterGraz, MedicalUniversityofGraz,Auenbruggerplatz29,8036Graz,Austria 2InstituteofAcupunctureandMoxibustion,ChinaAcademyofChineseMedicalSciences,Beijing100700,China CorrespondenceshouldbeaddressedtoGerhardLitscher;[email protected] Received1November2013;Accepted1November2013 Copyright©2013GerhardLitscheretal. This is an open access article distributed under the Creative Commons Attribution License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly cited. Thisisanannualspecialissue.Thecurrentissueisthe2013 (iv)scientific evaluation of complementary medical issuewhichincludeseleveninterestingpapers. methods(acupuncture,electroacupuncture,andlow Acupuncture has been used for medical treatment for levellasertherapy), thousands of years. A large number of empirical data is (v)clinicaleffectsofacupuncture, available, but the technical quantification of effects was not (vi)intravenouslaserbloodirradiation, possible up to now. Using electroacupuncture, needle, or laserstimulationandmodernbiomedicaltechniques,itwas (vii)laserneedleacupuncture, possible for the first time to quantify changes in biological (viii)redandinfraredlaserstimulation, activitiescausedbyacupuncture. (ix)auricularacupuncturewithlaser, As mentioned above, this special issue contains eleven publications, of which six are related to laser acupuncture, (x)biomedicalassessmentofacupuncture, three to electroacupuncture, two to needle acupuncture, Modernization of acupuncture is performed by high-tech and one to photoluminescent bioceramic material. Apart acupuncture and integrative laser stimulation. Eastern and from body acupuncture, special emphasis is also given to Western medicine are getting closer to each other using auricularacupuncture.Onereviewarticle,22pagesinlength, modernbiomedicalengineeringtechnology,asdescribedin deals with the topic auricular acupuncture with laser. The thisannualspecialissue. investigationscoveranimalexperimentalstudiesandstudies inhealthyvolunteers,pretermneonates,andpatients,aswell as basic and clinical research on evidence-based high-tech ConflictofInterests acupuncture, integrative laser irradiation, and translational Theauthorsstatethatthereisnoconflictofinterestsregard- medicine. ingthepublicationofthiseditorial. Ithastobementionedthatthisannualspecialissue2013 contains,amongothers,thefollowingtopics: Acknowledgments (i)modernization of acupuncture (evidence-based medicine,integrativelasermedicine), As in the first annual special issue, the Lead Guest Editor againwishestothanktheotherthreeGuestEditors,Professor (ii)high-techacupuncture, Bing Zhu, (Director of the Institute of Acupuncture and (iii)development of innovative acupuncture stimulation Moxibustion,ChinaAcademyofChineseMedicalSciences, methods, Beijing, China), Associate Professor Xin-Yan Gao (Head of 2 Evidence-BasedComplementaryandAlternativeMedicine theDepartmentofPhysiology,InstituteofAcupunctureand Moxibustion,ChinaAcademyofChineseMedicalSciences, Beijing,China),andProfessorLuWang(StronachResearch UnitforComplementaryandIntegrativeLaserMedicineand TCM Research Center Graz, Medical University of Graz, Graz,Austria),fortheexcellentcooperation.Inthiscontext, I would also like to thank all authors for their excellent contributions and patience during the review process. The workofallreviewersonthepaperswithinthisspecialissueis highlyappreciated. We want to thank Ms. Ingrid Gaischek (Stronach Research Unit for Complementary and Integrative Laser Medicine,ResearchUnitofBiomedicalEngineeringinAnes- thesia and Intensive Care Medicine, and TCM Research CenterGraz,MedicalUniversityofGraz,Graz,Austria)for hervaluablesupportineveryrespect. GerhardLitscher Xin-YanGao LuWang BingZhu HindawiPublishingCorporation Evidence-BasedComplementaryandAlternativeMedicine Volume2013,ArticleID839132,5pages http://dx.doi.org/10.1155/2013/839132 Research Article Clinical Effect of Acupuncture on Endemic Skeletal Fluorosis: A Randomized Controlled Trial ZhouJincao,WuZhongchao,ChenZhongjie,ZhaoXiaoguang,HuJing,JiaoYue, LiGuiran,andPangLi AcupunctureandMoxibustionInstituteofChinaAcademyofChineseMedicalScience,Beijing100700,China CorrespondenceshouldbeaddressedtoWuZhongchao;[email protected] Received22August2013;Accepted16October2013 AcademicEditor:LuWang Copyright©2013ZhouJincaoetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense, whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited. Objective. To evaluate the effect of acupuncture on endemic skeletal fluorosis (ESF) through the randomized controlled trial. Methods.Ninety-ninecasesweredividedintothetreatmentgroup(68cases)andthecontrolgroup(31cases)randomly.Normal acupuncturecombinedwithelectroacupuncturewasusedintreatmentgroup,whileCaltratewithvitaminDtabletswereapplied incontrolgroup.After2courses,theVAS,urinaryfluoride,serumcalcium,andserumphosphatewereevaluatedbeforeandafter treatment.Results.Bothofthesetwomethodscouldrelievepaineffectivelyandtheeffectofacupuncturewasbetter(𝑃 < 0.05). Intreatmentgroup,thecontentofurinaryfluorideaftertreatmentwashigherthanbefore(𝑃<0.05),whilethecontentofserum calciumandphosphatewaslower(𝑃<0.05).Conclusion.Theeffectofacupunctureonrelievingpainandpromotingdischargeof urinaryfluorideisbetterthanthatofwesternmedicine.Acupuncturecanreducethecontentofserumcalciumandphosphate. 1.Introduction studiedprofoundlyandgetsapositiveeffect.Thedysfunction ofjointsactuallybelongstoafibrousankylosis,areversible Endemic fluorosis, known as endemic skeletal fluorosis change,whichresultsfromlowtensityofmuscle,tendon,and (ESF), is a kind of chronic poisoning disease caused by ligament, around the affected joint after pain relief [4]. The excessive intake of fluorine for a long time during people’s calciumcancoordinatewithfluorionintheintestinaltract, lives. It usually includes dental and skeletal fluorosis. The andthecoordinationcompound-calciumfluorideisexcreted disease, endemic skeletal fluorosis in drink-water type, is tolowertheabsorptionoffluorion;ontheotherhand,thediet caused by high content of fluorine in drinking water in structure with profuse calcium is suitable for patients with prevalentareas.Atpresent,thepandemicdiseasehasaffected skeletalfluorosis[5]. 35countriesandregions. Thestudyisdesignedasarandomizedcontrolledtrialand The pathogenesis of skeletal fluorosis is unclear, so the obeysthescientificresearchprincipleofrandom,blindness, method of descending fluorine though water improvement control,andsoforth,alsofollowstheTCMtreatingprinciple is the only effective one [1, 2], but it needs a long time for of promoting blood circulation to remove blood stasis, theeliminationoffluorineinbodyandtheimprovementof dispellingwindtoeliminatedampness,anddredgingcollat- clinical symptoms. Drug therapy usually includes chemical erals to resolve pain, and aims to evaluate the acupuncture elementssuchascalcium,magnesium,andaluminum,vita- treatment on skeletal fluorosis for 99 patients by means of mins,andaminoacid[3].Thoughthesedrugscanproduce clinicaloutcomesaspainalleviation,urinaryfluoride,serum certaineffect,theirunstableeffectandsideeffectsstillshould phosphate,andserumcalcium. beconsidered. This study applies acupuncture therapy to treat skeletal 2.MaterialsandMethods fluorosis,whichpromotesqicirculation,regulatesmeridians, dredges collaterals to relieve pain, and improves the joint 2.1. General Data. From May 2009 to June 2010, the motion. The mechanism of acupunctureanalgesia has been study enrolled 99 patients suffering from skeletal fluorosis
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