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Evidence-Based Complementary and Alternative Medicine High-Tech Acupuncture and Integrative Laser Medicine Guest Editors: Gerhard Litscher, Xin-Yan Gao, Lu Wang, and Bing Zhu High-Tech Acupuncture and Integrative Laser Medicine Evidence-Based Complementary and Alternative Medicine High-Tech Acupuncture and Integrative Laser Medicine Guest Editors: Gerhard Litscher, Xin-Yan Gao, Lu Wang, and Bing Zhu Copyright©2012HindawiPublishingCorporation.Allrightsreserved. Thisisaspecialissuepublishedin“Evidence-BasedComplementaryandAlternativeMedicine.”Allarticlesareopenaccessarticles distributedundertheCreativeCommonsAttributionLicense,whichpermitsunrestricteduse,distribution,andreproductioninany medium,providedtheoriginalworkisproperlycited. Editorial Board TerjeAlraek,Norway JulianoFerreira,Brazil CynthiaR.Long,USA ShrikantAnant,USA PeterFisher,UK IreńeLund,Sweden SedighehAsgary,Iran JoelJ.Gagnier,Canada GailMahady,USA HyunsuBae,RepublicofKorea M.NabeelGhayur,Canada JeanineL.Marnewick,SouthAfrica LijunBai,China AnwarulHassanGilani,Pakistan FrancescoMarotta,Italy SarangBani,India MichaelGoldstein,USA VirginiaS.Martino,Argentina VassyaBankova,Bulgaria SveinHaavik,Norway JamesH.McAuley,Australia WinfriedBanzer,Germany S.-H.Hong,RepublicofKorea AndreasMichalsen,Germany VernonA.Barnes,USA MarkusHorneber,Germany DavidMischoulon,USA DebraL.Barton,USA ChingLiangHsieh,Taiwan Hyung-InMoon,RepublicofKorea JairoKenuppBastos,Brazil BennyTanKwongHuat,Singapore AlbertMoraska,USA DavidBaxter,NewZealand RomanHuber,Germany MarkMoss,UK Andre´-MichaelBeer,Germany AlysonHuntley,UK MinKyunNa,RepublicofKorea AlvinJ.Beitz,USA AngeloAntonioIzzo,Italy VitalyNapadow,USA PaoloBellavite,Italy KanokwanJarukamjorn,Thailand F.R.F.Nascimento,Brazil YongChoolBoo,RepublicofKorea StefanieJoos,Germany IsabellaNeri,Italy FrancescaBorrelli,Italy Z.Kain,USA TB˙enoˆıtNguelefack,Cameroon GloriaBrusotti,Italy OsamuKanauchi,Japan MartinOffenbacher,Germany ArndtBu¨ssing,Germany KenjiKawakita,Japan Ki-WanOh,RepublicofKorea SubhashC.Mandal,India JongYeolKim,RepublicofKorea Y.Ohta,Japan LeighF.Callahan,USA Cheorl-HoKim,RepublicofKorea OlumayokunA.Olajide,UK RaffaeleCapasso,Italy YounChulKim,RepublicofKorea ThomasOstermann,Germany OpherCaspi,Israel YoshiyukiKimura,Japan StaceyA.Page,Canada Shun-WanChan,HongKong ToshiakiKogure,Japan Tai-LongPan,Taiwan Il-MooChang,RepublicofKorea ChingLan,Taiwan PatchareewanPannangpetch,Thailand Chun-TaoChe,USA AlfredLa¨ngler,Germany BhushanPatwardhan,India YunfeiChen,China LixingLao,USA BeritSmestadPaulsen,Norway Tzeng-JiChen,Taiwan CharlotteLeboeuf-Yde,Denmark AndreaPieroni,Italy KevinW.Chen,USA TatleangLee,Singapore RichardPietras,USA Juei-TangCheng,Taiwan MyeongSooLee,RepublicofKorea XianqinQu,Australia EvanPaulCherniack,USA Jang-HernLee,RepublicofKorea CassandraL.Quave,USA Jen-HweyChiu,Taiwan ChristianLehmann,Canada RojaRahimi,Iran JaeYoulCho,RepublicofKorea MarcoLeonti,Italy KhalidRahman,UK WilliamC.S.Cho,HongKong Ping-ChungLeung,HongKong CheppailRamachandran,USA Shuang-EnChuang,Taiwan ShaoLi,China KeRen,USA EdwinL.Cooper,USA Xiu-MinLi,USA Mee-RaRhyu,RepublicofKorea VincenzoDeFeo,Italy ChunGuangLi,Australia Jose´ LuisR´ıos,Spain RocioDelaPuerta,Spain SabinaLim,RepublicofKorea PaoloRobertidiSarsina,Italy AlexandraDeters,Germany WenChuanLin,China BasharSaad,PalestinianAuthority DrissaDiallo,Norway ChristopherG.Lis,USA AndreasSandner-Kiesling,Austria MohamedEddouks,Morocco GerhardLitscher,Austria A.RobertoSoaresSantos,Brazil AmrE.Edris,Egypt I.-MinLiu,Taiwan G.Schmeda-Hirschmann,Chile TobiasEsch,Germany KeLiu,China RosaSchnyer,USA YibinFeng,HongKong YijunLiu,USA AndrewScholey,Australia JosueFernandez-Carnero,Spain GaofengLiu,China VeroniqueSeidel,UK DanaSeidlova-Wuttke,Germany K.V.Trinh,Canada WolfgangWeidenhammer,Germany SenthamilR.Selvan,USA VolkanTugcu,Turkey JennyM.Wilkinson,Australia TuhinadriSen,India Yew-MinTzeng,Taiwan V.C.N.Wong,HongKong RonaldSherman,USA CatherineUlbricht,USA CharlieChangliXue,Australia KarenJ.Sherman,USA DawnM.Upchurch,USA HarukiYamada,Japan KanShimpo,Japan AlfredoVannacci,Italy NobuoYamaguchi,Japan B.-C.Shin,RepublicofKorea ManiVasudevan,Malaysia HitoshiYamashita,Japan Jian-nanSong,China JosephR.Vedasiromoni,India YongQingYang,China RachidSoulimani,France CarloVentura,Italy KenYasukawa,Japan ElisabetStener-Victorin,Sweden WagnerVilegas,Brazil E.Yesilada,Turkey MohdRoslanSulaiman,Malaysia PradeepVisen,Canada M.Yoon,RepublicofKorea VenilN.Sumantran,India AristoVojdani,USA HongQ.Zhang,HongKong TokuTakahashi,USA DietlindWahner-Roedler,USA HongZhang,China TakashiTakahashi,Japan Chong-ZhiWang,USA BoliZhang,China RabihTalhouk,Lebanon Shu-MingWang,USA RuixinZhang,USA JoannaThompson-Coon,UK ChenchenWang,USA HaiboZhu,China MeiTian,China Y.Wang,USA YaoTong,HongKong KenjiWatanabe,Japan Contents High-TechAcupunctureandIntegrativeLaserMedicine,GerhardLitscher,Xin-YanGao,LuWang, andBingZhu Volume2012,ArticleID363467,2pages LongitudinalAnti-MllerianHormoneinWomenwithPolycysticOvarySyndrome:AnAcupuncture RandomizedClinicalTrial,JasonFranasiak,StevenL.Young,ChristopherD.Williams,andLisaM.Pastore Volume2012,ArticleID973712,7pages HowtoDesigntheControlGroupinRandomizedControlledTrialsofAcupuncture?,Jaung-GengLin, Chao-HsunChen,Yu-CheHuang,andYi-HungChen Volume2012,ArticleID875284,7pages LocalandSystemicCardiovascularEffectsfromMonochromaticInfraredTherapyinPatientswithKnee Osteoarthritis:ADouble-Blind,Randomized,Placebo-ControlledStudy,Ru-LanHsieh,Wei-ChengLiao, andWen-ChungLee Volume2012,ArticleID583016,9pages EvaluationoftheEffectsofAcupunctureonBloodFlowinHumanswithUltrasoundColorDoppler Imaging,ShinTakayama,MasashiWatanabe,HirokoKusuyama,SatoruNagase,TakashiSeki, ToruNakazawa,andNobuoYaegashi Volume2012,ArticleID513638,8pages DevelopmentandClinicalApplicationofaPreciseTemperature-ControlDeviceasanAlternatefor ConventionalMoxibustionTherapy,ShinTakayama,ShigeruTakashima,JunnosukeOkajima, MasashiWatanabe,TetsuharuKamiya,TakashiSeki,MiyakoYamasaki,NobuoYaegashi,TomoyukiYambe, andShigenaoMaruyama Volume2012,ArticleID426829,6pages TemperatureandSafetyProfilesofNeedle-WarmingTechniquesinAcupunctureandMoxibustion, X.Y.Gao,C.Y.Chong,S.P.Zhang,K.W.E.Cheng,andB.Zhu Volume2012,ArticleID168393,6pages MathematicalReflectionsonAcupointCombinationsintheTraditionalMeridianSystems, SvenSchroeder,SusanneEppleé,JianweiZhang,GesaMeyer-Hamme,ThomasFriedemann,andWeiguoHu Volume2012,ArticleID268237,10pages RoleofAC-cAMP-PKACascadeinAntidepressantActionofElectroacupunctureTreatmentinRats, Jian-huaLiu,Zhi-fengWu,JianSun,LiJiang,ShuoJiang,andWen-binFu Volume2012,ArticleID932414,7pages SystemIdentificationAlgorithmAnalysisofAcupunctureEffectonMeanBloodFluxofContralateral HeguAcupoint,GuangjunWang,JianguoHan,GerhardLitscher,andWeiboZhang Volume2012,ArticleID951928,7pages ExplorationofNewElectroacupunctureNeedleMaterial,SanghunLee,Gwang-HoChoi, ChangHoonLee,YuKyoungKim,SaebhomLee,SungjinCho,SunheeYeon,Sun-MiChoi, andYeon-HeeRyu Volume2012,ArticleID612545,10pages HeterogeneityofSkinSurfaceOxygenLevelofWristinRelationtoAcupuncturePoint,MinyoungHong, SarahS.Park,YejinHa,JaegeunLee,KwangsikYoo,Gil-JaJhon,MinahSuh,andYoungmiLee Volume2012,ArticleID106762,7pages ThermographicalMeasuringoftheSkinTemperatureUsingLaserNeedleAcupunctureinPreterm Neonates,WolfgangRaith,GerhardLitscher,IrisSapetschnig,SebastianBauchinger,EvelyneZiehenberger, WilhelmMller,andBerndtUrlesberger Volume2012,ArticleID614210,5pages TheEffectsofScrapingTherapyonLocalTemperatureandBloodPerfusionVolumeinHealthySubjects, Qin-YanXu,Jin-ShengYang,BingZhu,LiYang,Ying-YingWang,andXin-YanGao Volume2012,ArticleID490292,6pages Sino-EuropeanTranscontinentalBasicandClinicalHigh-TechAcupunctureStudies—Part4:“Fireof Life”AnalysisofHeartRateVariabilityduringAcupunctureinClinicalStudies,GerhardLitscher, Lin-PengWang,LuWang,Cun-ZhiLiu,andXiao-MinWang Volume2012,ArticleID153480,5pages NMDAReceptorsofGastric-ProjectingNeuronsintheDorsalMotorNucleusoftheVagusMediatethe RegulationofGastricEmptyingbyEAatWeishu(BL21),XinZhang,BinCheng,XianghongJing, YongfaQiao,XinyanGao,HuijuanYu,BingZhu,andHaifaQiao Volume2012,ArticleID583479,7pages TechnicalParametersforLaserAcupuncturetoElicitPeripheralandCentralEffects:State-of-the-Artand ShortGuidelinesBasedonResultsfromtheMedicalUniversityofGraz,theGermanAcademyof Acupuncture,andtheScientificLiterature,GerhardLitscherandGerhardOpitz Volume2012,ArticleID697096,5pages Sino-EuropeanTranscontinentalBasicandClinicalHigh-TechAcupunctureStudies—Part3:Violet LaserStimulationinAnesthetizedRats,Xin-YanGao,GerhardLitscher,KunLiu,andBingZhu Volume2012,ArticleID402590,8pages Laser-InducedEvokedPotentialsintheBrainafterNonperceptibleOpticalStimulationattheNeiguan Acupoint:APreliminaryReport,GerhardLitscher,GuentherBauernfeind,GernotMueller-Putz, andChristaNeuper Volume2012,ArticleID292475,6pages IntegrativeLaserMedicineandHigh-TechAcupunctureattheMedicalUniversityofGraz,Austria, Europe,GerhardLitscher Volume2012,ArticleID103109,21pages BiomedicalTeleacupuncturebetweenChinaandAustriaUsingHeartRateVariability—Part2:Patients withDepression,GerhardLitscher,GuangyuCheng,LuWang,WeipingCheng,HangSu,QianqianNiu, TianyuZou,YongyueWang,XiaoFeng,IngridGaischek,ZeminSheng,andHaixueKuang Volume2012,ArticleID145904,5pages ManualandElectroacupunctureforLabourPain:StudyDesignofaLongitudinalRandomized ControlledTrial,LindaVixner,LenaB.Ma˚rtensson,ElisabetStener-Victorin,andEricaSchytt Volume2012,ArticleID943198,9pages Sino-EuropeanTranscontinentalBasicandClinicalHigh-TechAcupunctureStudies—Part2:Acute StimulationEffectsonHeartRateandItsVariabilityinPatientswithInsomnia,GerhardLitscher, GuangyuCheng,WeipingCheng,LuWang,QianqianNiu,XiaoFeng,IngridGaischek,andHaixueKuang Volume2012,ArticleID916085,5pages Sino-EuropeanTranscontinentalBasicandClinicalHigh-TechAcupunctureStudies—Part1:Auricular AcupunctureIncreasesHeartRateVariabilityinAnesthetizedRats,Xin-YanGao,KunLiu,BingZhu, andGerhardLitscher Volume2012,ArticleID817378,7pages AnInnovativeHigh-TechAcupunctureProduct:SXDZ-100NerveMuscleStimulator,ItsTheoretical Basis,Design,andApplication,XinyanGao,PeijingRong,LiangLi,WeiHe,HuiBen,andBingZhu Volume2012,ArticleID626395,6pages AuricularAcupunctureMaySuppressEpilepticSeizuresviaActivatingtheParasympatheticNervous System:AHypothesisBasedonInnovativeMethods,WeiHe,Pei-JingRong,LiangLi,HuiBen,BingZhu, andGerhardLitscher Volume2012,ArticleID615476,5pages TranscutaneousElectricalNerveStimulationonthePC-5andPC-6PointsAlleviatedHypotensionafter EpiduralAnaesthesia,DependingontheStimulusFrequency,Young-ChangP.Arai,AkihiroIto, KenjiOhshima,SokiHibino,SinnosukeNiwa,JunKawanishi,HirokiNumanami,YoshikazuSakakima, ShoujiMizuno,YusukeTawada,YukiMaruyama,JunSato,MakotoNishihara,ShinsukeInoue, andTakahiroUshida Volume2012,ArticleID727121,4pages HindawiPublishingCorporation Evidence-BasedComplementaryandAlternativeMedicine Volume2012,ArticleID363467,2pages doi:10.1155/2012/363467 Editorial High-Tech Acupuncture and Integrative Laser Medicine GerhardLitscher,1,2Xin-YanGao,1,2LuWang,1andBingZhu2 1StronachResearchUnitforComplementaryandIntegrativeLaserMedicine,ResearchUnitofBiomedicalEngineeringin AnesthesiaandIntensiveCareMedicine,TCMResearchCenterGraz,MedicalUniversityofGraz,8036Graz,Austria 2InstituteofAcupunctureandMoxibustion,ChinaAcademyofChineseMedicalSciences,Beijing100700,China CorrespondenceshouldbeaddressedtoGerhardLitscher,[email protected] Received19July2012;Accepted19July2012 Copyright©2012Gerhard Litscher et al. This is an open access article distributed under the Creative Commons Attribution License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly cited. Basicresearchonhigh-techacupunctureandintegrativelaser andmoxibustion.Afirstintroductionofnewdevelopments medicinehasbeensuccessfullyperformedallovertheworld of acupuncture stimulation equipment is also featured duringthelastdecades,usingabroadspectrumofinnovative amongthepapers. biomedical engineering methods. One of the main goals is Ithastobementionedthatthisspecialissuehasatotal to combine basic research on high-tech acupuncture with impactfactorof124.124andcontains,amongothers,thefol- necessary further experimental and clinical pilot studies lowingtopics:(i)modernizationofacupuncture(evidence- for the first time. Acupuncture has been used for medical based medicine, integrative laser medicine), (ii) high-tech treatmentforthousandsofyears.Usingelectroacupuncture, acupuncture, (iii) development of innovative acupuncture needle or laser needle stimulation, and modern biomedical stimulation methods (needle, laser, and electroacupunc- techniques, it was possible for the first time to quantify ture), (iv) methods for the quantification of peripheral changesinbiologicalactivitiescausedbyacupuncture. and central effects of acupuncture, (v) scientific evaluation The patient is in China—the analysis for the effi- of complementary medical methods (acupuncture, acu- cacy of acupuncture is performed by experts in Europe. pressure, moxibustion, and laser therapy), (vi) computer- This “transcontinental teleacupuncture” is a way which was controlled acupuncture, (vii) teleacupuncture, (viii) laser realized by our research team within joint Sino-Austrian needleacupuncture,(ix)red-andinfraredlaserstimulation, and Sino-European projects. The investigations are carried (x) violet laser acupuncture, (xi) biomedical assessment of out over thousands of kilometers; for example, 24-hour acupuncture. electrocardiographic (ECG) recordings from patients are Modernization of acupunctureis a contemporary issue. registered in China, and the data are transferred directly The bridging between Eastern and Western medicine was after the acupuncture treatment to an analysis computer at successfulusingmodernbiomedicalengineeringtechnology, theMedicalUniversityofGraz.TheacupuncturistsinChina asdescribedinthisspecialissue.Thenexttaskistomakethe are informed about the results immediately based on the arising possibilities and results useable for all involved per- analysisprotocol. sons. These Sino-European studies included this special issue that contains 26 interesting publications, of which 12 are Acknowledgments relatedtoneedleacupuncture,5tolaseracupuncture,and9 to electroacupuncture. Apart from body acupuncture, spe- The lead guest editor thanks the other three guest editors, cial emphasis is also given to auricular acupuncture. The Professor B. Zhu, M.D. Ph.D. (Director of the Institute of investigationscoveranimalexperimentalstudiesandstudies Acupuncture and Moxibustion, China Academy of Chinese inhealthyvolunteersandpatients,aswellasbasicandclinical Medical Sciences, Beijing, China), Associate Professor Xin- researchonevidence-basedhigh-techacupuncture,integra- YanGao,M.D.Ph.D.(HeadoftheDepartmentofPhysiology, tivelaser,andtranslationalmedicinebasedonacupuncture InstituteofAcupunctureandMoxibustion,ChinaAcademy

Description:

Benny Tan Kwong Huat, Singapore. Roman Huber, Germany .. of acupuncture stimulation equipment is also featured among the papers. It has to be mentioned .. The comparison cohort is graphed as a heavy red line in. Figure 3.