Heart Transplantation

314 Pages·2023·7.45 MB·English

by  Hashim Talib Hashim, Naseer Ahmed, Giuseppe Faggian, Martí Manyalich, Francesco Onorati

Heart
Transplantation
Hashim Talib Hashim
Naseer Ahmed
Giuseppe Faggian
Martí Manyalich
Francesco Onorati
Editors
Heart Transplantation
· ·
Hashim Talib Hashim Naseer Ahmed
· ·
Giuseppe Faggian Martí Manyalich
Francesco Onorati
Editors
Heart Transplantation
Editors
Hashim Talib Hashim Naseer Ahmed
College of Medicine Rehman Medical Institute
University of Baghdad Hayatabad, Peshawar, Pakistan
Baghdad, Iraq
Martí Manyalich
Giuseppe Faggian Parc Científic de Barcelona
Department of Cardiac Surgery President of Donation and Transplantation
Azienda Ospedaliera Universitaria Integrata Barcelona, Spain
Verona
Verona, Italy
Francesco Onorati
Division of Cardiac Surgery
University of Verona
Verona, Italy
ISBN 978-3-031-17310-3 ISBN 978-3-031-17311-0 (eBook)
https://doi.org/10.1007/978-3-031-17311-0
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To my family: my father (Talib), my mother
(Jawaher), and my grandmothers (Hamdia
and Alya).
To my grandfathers (Hashim and Mutar),
hoping they are resting in peace.
To my uncle (Abbas) and aunts (Shafaa and
Rasha).
To all my friends and especially Mustafa,
Mohammed, Ahmed, Zanyar, Mahdi, and
Abdalla.
Finally, to those who supported me and be
with me all the times passed and still being
my support, my brothers (Ali, Mustafa,
Mujtaba, Hussein, and Mortada), my sister
(Noor Alhuda), my nephew (Razan), and my
brother’s wife (Zainab).
Preface
Heart Transplantation: Theory and Practice is a translational and comprehensive
reference which broadly covers a range of topics within Heart Transplantation
including surgical procedure, requirements, potential complications, and follows up
with the most up-to-date research and literature review. The book first lay out the
anatomy, physiology, embryology, and pathology of the heart as an introduction,
then goes into the details of cardiac transplantation including the surgical proce-
dure, the potential complications, and cardio-immunology. It also delves into other
aspects of heart transplantation including organ procurement, religious aspects, the
ethical issues that can emerge prior or during the surgery, and artificial heart. Then
it explores multi-organ transplantations including transplants that have been done
in the specialized centers and their outcomes and complications. All these topics
are discussed in a scientific medical language with illustrations and charts to aid
understanding, allowing readers to gain a full understanding of the whole procedure
easily.
This book is—to our knowledge—the first book that vastly focuses on cardiosur-
gical and medical aspects of heart transplantation, emerging from the significant need
to fill a defect in the related cardiology and surgical resource map and incorporate
meaningful updates regarding all aspects of the procedures. Many books were dedi-
cated to the subject over the years, but those were rather superficial, immunological,
or pathological.
“Heart Transplantation Surgery: Theory and Practice” is composed of 12 chapters,
containing concise and up-to-date information within about 200 pages.
The book contains around 100 diagrams, tables, illustrations, and figures
attempting to make it more interesting and easier to memorize by readers.
More than 70 single-best-answer multiple choice questions (MCQs), distributed
along the chapters, cover important aspects of heart transplantation surgery, from the
basic sciences to ultimately surgery.
Authors believe that heart transplantation has many aspects that should be more
widely discussed, and through this proposed book the authors hope to stimulate
further research and clinical trials for heart transplantation, as well as more discussion
in the field especially related to the ethical and religious aspects. The book also
vii
viii Preface
focuses on multi-organ transplantations including heart and artificial heart, and how
this could be developed to solve the problem of lack of donors. At the end of each
chapter, a list of MCQs related to the topics of that chapter and a list of references that
readers can look up for additional information are provided. What makes our book
novel is that the book looks at heart transplantation from all the aspects of medicine
and surgery in addition to the ethical issues. It is written in simple medical language
that makes it possible for various medical healthcare workers and students to build
their knowledge base about the topic.
It talks about these topics from the surgical perspective and covers the details of
heart transplantation surgery in a step-by-step fashion. In this book, we are presenting
new, unique, and sequenced surgical guidelines in heart transplantation surgery either
in childhood or adulthood with pros and cons. Detailed ways with highly organized,
attractive graphs and photos will make this book easily understandable for medical
students, surgical residents, and surgeons alike. Finally, we have put more than 30
multiple-choice questions at the end of each chapter that cover all the topics and
subjects discussed within that chapter. These could serve to boost the question banks
for medical schools and residency programs.
Baghdad, Iraq Hashim Talib Hashim
Peshawar, Pakistan Naseer Ahmed
Verona, Italy Giuseppe Faggian
Barcelona, Spain Martí Manyalich
Verona, Italy Francesco Onorati
25 October 2022
Contents
Anatomy of the Heart .............................................. 1
Rema Yousif Bakose, Ahmed Dheyaa Al-Obaidi,
Mustafa Najah Al-Obaidi, Hasan Al-Abbasi,
Mohammed Omer AL-Bayati, Ali Talib Hashim, Abdullah Muhanned,
Adil Alhaideri, and Jaafar Dhiaa Al-Dabagh
Physiology of the Heart ............................................ 19
Mustafa Raad Kamil
Embryology of the Heart ........................................... 49
Abbas Mohammad, Adil Alhaideri, and Zanyar Qais
The Pathological Changes Seen in Cardiac Diseases Indicated
for Transplantation ................................................ 67
Ahmed Dheyaa Al-Obaidi, Mohammed Tareq Mutar, Mustafa Majid,
Sara Shihab Ahmad, Rema Yousif Bakose, Mustafa Najah Al-Obaidi,
Hasan Al-Abbasi, Shaymaa Saadi Shaalan, and Mustafa Ismail
Cardioimmunology and Heart Transplantation ....................... 97
Ali Talib Hashim, Ahed El Abed El Rassoul, Inas Khalifa Sharquie,
and Haya Mohammed Abujledan
Heart Failure Outcomes and Management ........................... 111
Ibad Ur Rehman, Khadija Iqbal, Vanya Ibrahim, Alaa bakhtyar,
and Belan Mikael
Donor Management and Organ Procurement ........................ 117
Annalisa Bernabei, Ilaria Tropea, Giuseppe Faggian,
and Francesco Onorati
Heart Transplantation Procedure ................................... 129
Abbas Mohammad
ix
x Contents
Complications and Follow Up ....................................... 155
Morad Al Mostafa, Qasim Mehmood, Haya Mohammed Abujledan,
and Maryam Salma Babar
Outcomes and Impact on Life Quality ............................... 177
Ilaria Tropea, Annalisa Bernabei, Giuseppe Faggian,
and Francesco Onorati
Heterotopic Heart Transplantation .................................. 199
Mohammed Mohammed Hussein
Artificial Heart, Cellular, Regenerative, and Xenotransplantation ...... 219
Ali Talib Hashim, Ibrahim Dheyaa Al-Hasani, and Rebecca Caruana
Multi-organ Transplantation ....................................... 231
Fahtiha Nasreen, Tasnia Noor Salim, Avishek Kunda,
Ibad Ur Rehman, Maryam Aman, and Rebecca Caruana
Ethical Issues of Heart Transplantation .............................. 249
Tonazzina Hossain Sauda, Myesha Maliha Binte Mamun,
Asadur Rahman Nabin, Monzer Ousseily, and Sarah Meribout
Cultural and Religious Aspects of Heart Transplantation .............. 271
Jose-Maria Dominguez-Roldan, Ikran ul Haq, Naseer Ahmed,
Visist Dhitavat, Feng Huo, Jie Zhao, and Marti Manyalich-Vidal
Bridging Strategies for Heart Transplantation ........................ 295
Ahmed Gamal Abouarab, Mohammed Mustafa Mohammed,
Karim Heweidy, and Abdelrahman Mohamed Nasreldin
Heart Memory and Feelings ........................................ 305
Ali Talib Hashim, Ahmed Sattar Albayati, and Ethar Nazal
Index ............................................................. 311