. ,^'v'•: ..J9/ . •- ^'- '/'>• •'• '''.ixa . -ti •:j. .r- 1»>- ' 1 '"..•< -1 ' •, • It . •4.^ - f->] •'>' /.'.v* ;^l'•' ', '^ ^ ' "- ' -''.,''*.' '' \;. ,.\^ '''' 'v '"'r- '.'.''/''•'. ;\' i r- ;-,'f^ ' V'^i."•, ' , 1 i; •1? '('* -:U, f\\ i •.-<%,.' '. '* * .''" m'.^i^ii r," \^^H 'I. ^. 'V'- «5 ' - >: >' ''^-^ .- i "^1 y^ .'• '''•. r-' Harvard Medical ALUMNI BULLETIN SPRING 1996 :^t- •_» IB » "'" E>lil H.-m IMgr M> HIiKli.-s 1:^0:.' P'M .D if.> Take two aspirins r ^and me e-mail the morning. in ^^^^^^^^^ '^^^^H i j^5 ^^S ' The Virtual Physician THE TRAGEDY THAT ISN'T SHE HAS CANCER. THAT IT'S WHEN WAS THIS PICTURE WAS TAKEN SHE MISSING HER TREATMENT. It's sad, but true. You see, even thoush medical science has siven more cancer more Datients iope than ever before, one of the most critical challenses facins these people is simply settins to their treatments. But you can help. And we hope you will. Throush the American Cancer Society's Road To m^. Recovery prosram, you can volunteer to drive a cancer patient to and from J^-^ ?^^^ treatment. And, in turn, help them enjoy a fuller, lonser life. To find out more, call your American Cancer Society at 1 -800-ACS-2345. Because the only thins sadder than we AMERICAN this picture is that have more of V CANCER them. f SOCIETY' THERE'S NOTHING MIGHTIERTHANTHESWORD Harvard Medical Spring 1996 Volume 69 Number ALUMNI BULLETIN , 14 TheNextGeneration 44 BraveNewInterviewer byRobeitA. Greenes by WarnerSlack Health care has metcyberspace and Thehistoryand dynamics ofusing willneverbe the same. computers forpatientinteractions. 20 MedicineOn-Line 50 TheSeniorSetonthe Net byJeromeKassirer by GeorgeRichardson More revolutionarythan the Vistas andvalleys on the information CoverphotobyStuartDarsch currentrestructuringinhealth care highway. maybe cultural changes due to the computer. Departments 3 Letters 22 SolitaireConfinement by WilliamIraBennett 4 Pulse Whatthis countryneeds as badlyas Geriatric education, newInstitute of aV-chipis a G-chip to blockout Medicine members, second-year seductive computer games. show, newprofessorships, HST 25th TheGiantBrainstorm anniversary, HMS andJapan exchange byEllen Barlow students, centerto studydrugabuse and managed care, firstExcellence in 27 HMSSpinsaWeb MentoringAward, centerformini- by TerriL. Rutter mallyinvasive surgeryopened, The medical school's on-line face Howard HughesMedical Institute to theworld. grant. elicitTripThroughtheBrain byEllen Barlow 10 President'sReport GettingStarted byStephanieH. Pincus by TernL. Rutter 11 OntheQuadrangle 32 Operatingin3-D HMS-BIHealthcare Foundation, byEllen Barlow juncture oflaw andmedicine. Real-time image-guidedsurgeryis avirtual reality. 53 Alumni Notes 36 Tel-a-Doctor 59 In Memoriam by TeiTiL. Rutter Alexander Bill Telemedicine maybe creatinga Lewis Dexter global medicalvillage. 62 Death Notices 40 Digital Clinic byLuke Sato Usingmultimediain case-based learning and beyond. Slightin Hand by TeiriL. Rutter Inside hmab Harvard Medical BULLETIN A L u M N In the lastyear or so, several ofmy patients have said something Editor-in-chief WilliamIraBennett'68 like the following: "I read about those drugs on the Web, and I really don't want to take one ofthem" or "Do you think I should EEdlilteonrBarlow take X? I read about it on the Web." Thus, what only recently AssociateEditor seemed futuristic to me is starting to lookvery much like the pre- TerriL.Rutter sent. I don't suppose the essays in this edition ofthe Bulletin will AssistantEditor SarahJaneNelson be out ofdate by the time this issue reaches you, but I confess they seem less visionary than when we first started reading the manu- EditorialBoard ElissaA.Ely'88 scripts. MelindaFan'96 RobertM.Goldwyn'56 As Robert Greenes contends, information is becoming radical- JoshuaHauser'95 ly less centralized in the new world ofthe Internet. In manyways, VPiacutloariAa.JMochEnvsooyn''7854 this will doubtless be a Good Thing, though from time to time, it JamesJ.O'Connell'82 GabrielOtterman'91 may also be problematic. To pursue my humble example, most DeborahProthrow-Stith'79 GuillermoC.Sanchez'49 physicians are accustomed to having patients come in with infor- J.GordonScarmell'40 mation from a current best-seller (in my case. Listening to Prozac or JEolhenanDo.rSSthooercekl'e55'47 Driven to Distraction). It is quite a different experience when this RichardJ.Wolfe information comes from a community ofpatients describing their DesignDirection SametzBlackstoneAssociates,Inc. experience on the Web. There can be little doubt that the Web will increasingly ASstseopchiaatniioenHOf.fiPciernscus'68,president "democratize" medical information.Jerome Kassirer, editor of The SuzanneFletcher'66,president-electi RobertS.Lawrence'64,president-elect2 New EnglandJournalofMedicine, sketches a view ofhow this might RomanW.DeSanctis'55,vicepresident NancyA.Rigotti'78,secretary work, and ofhow medical care may overcome certain limitations ArthurR.Kravitz'54,treasurer ofspace and time through the burgeoning capacity ofcomputer Councillors and network systems. KennethRolandBridges'76 DavidP.Gilmour'66 Other contributors to this issue ofHMAB describe various ways KatherineL.Griem'82 DanaLeifer'85 in which new computer technology is changing the reach ofour SharonB.Murphy'69 knowledge and understanding. For most, this takes the form ofa GilbertS.Omenn'65 BruceJ.SamsJr. '55 dramatic enhancement ofintellectual resources or mental capacity. JohnB.Stanbury'39 LorraineDudleyStanfield'87 (I offer a minor autobiographical exception to this trend.) DirectorofAlumniRelations With this issue ofHMAB we must say goodbye to Associate DanielD.Federman'53 We Editor Terri L. Rutter. have greatly benefited from her prose, RepresentativetotheHarvardAlumniAssociation passion, vision and humor. Ms. Rutter has led us into the myster- Chesterd'Autremont'44 ies ofthe Internet, and she was the moving spirit behind the issue IDStatement: celebrating 50 years ofwomen at HMS. Both in signed articles and TquhaertHearil-yuaatrd25MeSdhiactatluAclkuSmtnreietB,ulBloetsitnonis,pAuLb\l0i2sh1e1d5 We ©bytheHarvardMedicalAlumniAssociation. in tactful editing she has helped to shape this magazine. thank Telephone:(617)432-1548.Emailaddress: her and wish her all the best as she moves into the next phase of [email protected] paidatBoston,Massachusetts.Postmaster,sendform her writing career. 3579to25ShattuckStreet,Boston,MA02115, ISSN0191-7757.PrintedintheU.S.A. William Ira Bennett ^68 HarvardMedicalAlumni Bulletin Letters John Schott, M.D. HMS '66 InvestmentAdvisor ObstructedView the seed moneyfor a largersum. In Managed accounts, The articles onthe topic ofHMOs and anycase, I remain confused byyour retirement accounts, so called managed care (Winter '96) assumption that$500millionwould be family trusts were timelyandveryinteresting; how- required to renderHMS tuition-free. Dr. Schott provides highly ever, somepageswereverytryingto Assumingthatin today's market personalized investment read. Pagesprinted on a grayback- HMS could obtain a (tax-free) return on management to individuals, ground ofvaryingdensitywere diffi- investmentofatleast 10 percent, 5 families and institutions cultto see clearly, especiallyunder percentwould generate $25 million, artificial light. And lastly, "Changes in enough to more than equal the annual His unique approach and theAmphitheatre" in three divided tuition bills of1,000 students (HMS has established record merit your columns on each page added to the less than 700). I do notmean to befit- consideration frustrations oftrjdngto read my tle the taskofraisingsuch a sum; but We Schott Investment favorite alumnimagazine. older bymakingitunnecessarilylarge, you Corporation alums have trouble enoughwith our inhibitanyserious discussion ofgener- PublisherofTheSchottLetter sight. atingfunds forsuch a purpose. 120Centre Street Arewetttyingtoo hard to be However, when the total costofsup- Dover, MA02030 trendy? porting astudentfor oneyear atHMS (508) 785-9996 • AlbertP. Ley '^^B approaches the annual income ofthe RegisteredInvestmentAdvisor averageAmerican family, novel solu- SECandCommonwealthof Grammatical Error tions must be soughtand testedwith Massachusetts Asentence in the recentissue (Winter real urgency. '96, P56) reminds me ofthe oldNew Itis ironic thatin the same issue of Yorkerquips: "Clementwas a psychia- theBulletin, theAlumni Councilis tristwho specialized in the treatment described as searchingfor "creative ofalcoholism on the staffofBuffalo ways to dealwith financial issues," General Hospital." withoutanyreference to the UPenn Buffalo is a toughplace to live but... (oranyother) initiative. Further, HMS EugeneE. Nattie '77 announces its pride in generatingfel- lowships forjunior facultywho, more CreativeSupport than likely, need the income to help Iwasveryinterested inyourcolumn in payofftheirstudentloans! the Winter '96Bulletin announcing Instead ofrepetitive solicitations of the arrival ofCushing Robinsonto moneyfrom alumni/ae to help the superintend the developmentcam- needieststudents from drowningin paign forHMS. Iwas heartened that debtwhile forcingmore affluentfami- HMS had chosen someonewith experi- lies to subsidize tuition for those encewith the Universityof unable to pay, shouldn'tHMS allocate PennsylvaniaMedical School's effort vigorous development effortto obtain- to realizewhatyousarcasticallyrefer inghard moneyfor a permanent to as the "pipe dream" ['a fantastic endowmentto defraytuition? notion orvain hope....from the fan- In an era ofdeclining income tasies induced bysmokingopium'] ofa expectations forphysicians (and tuition-fi-ee medical education forall increasing physician/physicianmar- students." riage), whatis Harvard teachingits There was insufficientdetail to studentswhen itencourages them to ascertainwhetherRobinson's $10 mil- aggravate theirindividual indebtedness lion allocation atPennwas enough to bymore than $100,000, orforces them generate the full tuition equivalent for to turn to theirparents to scavenge 24students, orwhetheritwas merely moneyfrom retirement funds orsib- Spring 1996 Letters Pulse lings' inheritances? Mixedwith the joy ABoostforGeriatric Medicine A$100,000 traininggrantfrom the ofbecominga doctorwill be the bit- The geriatric education center, partof JohnA. Hartford Foundation inNew terness ofprolonged financial hard- the HarvardMedical School Division Yorkwill assistthe school in the devel- ship. onAging, is developinga model edu- opmentofthe education program. Ifcreative thinkingornewinitia- cation program thatwill broaden the Levkoff, associate professorin social — — tives as well as funds are wanting, I scope ofgeriatric care. The program medicine, and Barbara Berkman, asso- and otherHMS graduateswill always be will train advanced-degree students in ciate directorofthe geriatric education eagerto help. ButIthinkthatperenni- an interdisciplinary approach to geri- centerand directorofsocialwork allydunningus to offsettuition is atrics, includingprimarycare skills. research atMGH, will coordinate the merelya stopgap measure. Ithas no Since 60 percentofall health care program's planningprocess. more grace, and farless moralweight, users are olderthan 65, almost every Underthe grant, the geriatric edu- thanassistingthe homeless. Itis time health care providersees elderly cation centerisworkingwith academic to reconsiderourpriorities so that patients and, accordingto Sue Levkoff, and clinical facultywithin Harvard and theyreflecta leadership role for director ofthe Harvard UpperNew at other educational institutions in the Harvard with regard to the support, as England Geriatric Education Center, Boston area to develop and initiate well as the content, ofmedical educa- physiciansneed topaymore attention fourproducts: a clinical teachingpath- tion. to givingthis population adequate and way, an interdisciplinarycurriculum Mark G. Perlroth '60 well-rounded care. forprovidinggeriatric care in the clin- "The care ofthe olderperson ical setting, interdisciplinarycommu- TooMuch Change demands this interdisciplinaryper- nication tools, and a model for I have putoffthis note (alongwith my spective because ofcomplex health teachingpatients and familymembers reducedyearly donation), because it care needs thatare exacerbated by to participate in planningtheirown gives me great pain to compose this. social determinants and outcomes as care. Ethical issues ofgeriatric primary While attendingmy 60th college well as environmental issues," says care will be emphasized in all aspects reunion, I thoughtIwould revisit Levkoff. ofthis education model. Vanderbiltand see howthingswere going. Itwas like mywalkinginto — some EastAsian school no responses to mygreetings and muchjabbering in BarbaraBerkman(left)andSueLevkoff foreign tongues. Then came the "MakingHerstory" issue (Spring '95) and the coverphoto awakened me (verysadly) as to what was goingon atAlmaMater. I am not prejudiced againstwomen as doctors, but the takeover ofthe school byaffir- mative action women studentsI can- notstand. Somethingisvery amiss among thosewho guide the admissions policy ofHarvardMedical School, and itis high time for a reversal ofthis trend. Ihad given a moderate sum to the schoolinmywill, butIhavehad my lawyer delete this. Iwillnotsupport this conversion. This upsets mevery much, butifthis is disloyalty, so be it. Wm. NeilCampbellJr. '^8 <M HarvardMedicalAlumni Bulletin FeltonEarls RobertGlickman FerencJolesz DavidLivingston Institute Honors Earls has been studyinghowsuch metabolism. The Institute ofMedicine ofthe factors as poverty, social devaluation, Joleszhas advanced imagingtech- National AcademyofSciences has physical and emotional abuse, and the niques used in neuroradiologyto guide appointed three newmembers from breakdown ofneighborhood commu- various surgicalinterventions. HarvardMedical School: FeltonEarls, nities can putchildren atriskformen- Recently, he spurred the development HMS professorofchild psychiatryand tal and emotional disorders. He is the ofaninnovativemagnetic-resonance HSPH assistantprofessorofhuman scientific director ofthe Projecton operatingenvironmentthatprovides behavior and development; Robert Human Developmentin Chicago surgeonswith real-time images oftis- Glickman, Herrman LudwigBlumgart Neighborhoods, a long-term studyof sues deep inside the brainand other ProfessorofMedicine atHMS and 9,000 children and theirfamilies. organs. (See storypage 32.) chairman ofthe Departmentof Glickman has studied the metabo- Livingston studies the DNAtumor Medicine atBethIsrael Hospital; and lism and absorption offats and virus SV40 and howitpromotes the FerencJolesz, HMS associateprofessor lipoproteins formorethan two cancerous growth ofmammalian cells. ofradiologyand director ofthe decades. Gfickman and colleagues dis- Livingston's group has also isolated Division ofMagnetic Resonance covered that the small intestine pro- and started defining the function ofa ImagingatBrigham andWomen's duces apoproteins thatcoat thevarious familyofproteins thatcontribute to Hospital. David Livingston, Emil Frei fat molecules as theytravel in the the growth ofmammalian cells; his Professor ofMedicine atHMS and bloodstream. His workhas helped laboratoryis partofan international chairoftheresearch executive com- reveal howfatmolecules make their effortto decipherthe basic biochemi- mittee atthe Dana-Farber Cancer wayinto the bloodstream from the calmechanisms thatthe Rb protein Institute, has been named to the diet, and underscores the important uses to maintain normal cell behavior. NationalAcademyofSciences. role ofthe intestine in hpoprotein TheSecond-YearShow expressedfearsofdebtin danceandsong: WhentheNewtisinthe SenateHouse AndHMOsareontherise MBAswillmoldhealthcare Andwelfare'sswiftdemise. Thisisthedawningofthe AgeofIndebtedness. Spring 1996 Pulse JudithPalfreyandT.BerryBrazelton DeanDanielTostesonisflankedbyFritzBach(left)andAnthonyMonaco. Three New ProfessorshipsFilled saidMonaco, in his tribute to the man HSTSilverJubilee Withthe finale of 1995 came the cele- whose name hewill carryonhis pro- TheHarvard-MIT Division ofHealth bration ofthreenewprofessorships fessorship. Monaco didnotpersonally Sciences andTechnology(hst)wel- and the selection oftheir firstincum- knowMedawar, who died in 1987, but comed back43 graduates fora 25th bents. Novemberwas a busymonthin he said thathe has pursuedMedawar's anniversarycelebration December 7 thefacultyroom, firstfeting two pro- line ofinquiryinto tissue transplanta- and 8, 1995. The HST SilverJubilee fessors in transplantation surgery, tion and its therapeutic applications honored the division's founders, show- FritzH. Bach '60 as the Lewis formore than 30years. Monaco is cased the achievements ofits alumni, Thomas ProfessorofSurgeryand chiefoforgan transplantation atthe and anticipated the future ofthe divi- AnthonyP. Monaco '56 as the Peter Deaconess. sionthrough discussionofits educa- MedawarProfessor ofSurgery, both T. BerryBrazelton is ahousehold tional and research activities. endowed bythe SandozPharmaceut- name forthosewho have children, and HSTis an interdisciplinarycollabo- ical Corporation. Then aweeklater, his namewill nowgrace the third new rative effortofHMS andMIT estab- Judith Palfrey, chiefofthe Children's professorship. Renowned forhis work lished in 1970 to focus science and Hospital division ofgeneral pediatrics, in child developmentand forcreating technologyonhuman healthprob- was saluted as the T. BerryBrazelton the neonatal behavioral assessment lems. "In 1970 combiningscience and ProfessorofPediatrics. scale, Brazelton haswritten 26 books engineeringwith compassionand care Bach, who is directorofthe Sandoz andmore than 180 scientific articles forpatientswas an untried idea," said Center ofImmunobiology atthe New and chapters. He was chiefof IrvingLondon '39, the founding England Deaconess Hospital, did his Children's Hospital's child develop- directorofHSTfor 15 years and apro- internship and medical residencyat mentunitfrom 1972 to 1989 andis fessor emeritus atbothHMS andMIT. NewYorkUniversity, where he said, professorofpediatrics emeritus. "We had to integrate two universities "LewisThomas became myfriend and JudithPalfi-eyis apediatricianwho with differentstrengths and decidedly mentor, who inspired byexample by has devotedherprofessional careerto differentcultures." providingwisdom and encourage- improvingcommunityhealth care ser- HST students optamongprograms ment." In 1964, underThomas's guid- vices forchildren. She recentlypub- thatlead to anMD, a combined ance, Bach developed the mixed lished the book Community Child MD/phD orjustaPho. In the historyof lymphocyte culture as a testfor tissue Health:AnAction FlanforToday. the program there have been 500 compatibilityfor transplantation, an "To be associatedwithT. Berry graduateswho receivedMDs (some of assaythatis still used fortissue tj^Ding. Brazelton's name has gotto be the whom also earned PhDs) and about 70 Though famous forhis poetic essays, greatesthonor," said Palfrey. "This is who gota PhD alone. HSTis one ofthe Thomas '37, who died in 1993, was an opportunityforus to listen and to five academicsocieties atHMS, renowned also as a medical scientist putthe child backin the center, back although forthe firsttwo preclinical whowrote prolificallyon avarietyof in the family, backin the community." years, HSTstudents attend separate interests, manyconcerned with the courses, atbothMIT and HMS. They hostresponse to infection. then join the restofthe medical stu- The otherprofessorshipinsurgery dents on thewards for clerkships. isnamedforPeterMedawar, apioneer The intentofthe HST curriculumis oftransplantation science and Nobel to "educate leaders in academicmedi- laureate forhis discoveries aboutrejec- cine and the biomedical sciences" and tion and "privileged" times fortrans- to imparta "quantitative and molecu- plantation. Though a zoologist, "Peter larunderstandingofpathophysiologic Medawarwas driven in his researchto processes."As summarized in a previ- help people solve clinical problems," ous course catalog: "Graduates appre- ciate therelevance offluid mechanics HarvardMedicalAlumni Bulletin