Handbook of Cholesterol: Biology, Function and Role in Health and Diseases

497 Pages·2016·3.816 MB·English

by  Ronald Ross Watson, Fabien De Meester (eds.)

of cholesterol
Biology, function and role in health
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ISBN 978-90-8686-276-4
edited by:
Human Health Handbooks no. 11
Ronald Ross Watson
ISSN 2212-375X
Fabien de Meester
Wageningen Academic 
P u b l i s h e r s
Wageningen Academic 
P u b l i s h e r s
Handbook of cholesterol

Handbook of
cholesterol
Biology, function and role in health and diseases
Edited by:
Ronald Ross Watson
Fabien de Meester
Human Health Handbooks no. 11
ISSN 2212-375X
Wageningen Academic
P u b l i s h e r s
Buy a print copy of this book at
www.WageningenAcademic.com/HHH10
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ISBN: 978-90-8686-276-4
e-ISBN: 978-90-8686-821-6 The individual contributions in this
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Table of contents
Acknowledgements 11
Preface 13
Fabien De Meester and Ronald Ross Watson, editors
Cholesterol and neurological functions
1. Hypercholesterolemia: a disease of the brain 17
R.B. Singh, M.A. Niaz, T. Takahashi, F. De Meester, A. Wilczynska, B. Saboo,
A. Maheshwari, G. Cornelissen, J. Singh and I.G. Telessy
2. Cholesterol and cognitive functioning in persons free from stroke and dementia 37
G.E. Crichton, K.J. Sullivan and M.F. Elias
3. The role of cholesterol in disorders of brain and behavior: human and animal perspectives 53
R.J. Stevenson and H.M. Francis
Cholesterol and cardiovascular health
4. Macrophage deposition of extracellular lipid particles with microdomains of ordered
cholesterol arrays 73
X. Jin and H.S. Kruth
5. Cellular cholesterol retention in atherosclerosis and direct anti-atherosclerosis therapy 89
A.N. Orekhov, E.A. Ivanova and Y.V. Bobryshev
6. Dietary cholesterol and the lack of evidence on heart disease risk 101
M.L. Fernandez and C. Blesso
7. Cholesterol: the most misunderstood marker 117
B. Lands
8. Sphingosine-1-phosphate-rich high-density lipoprotein in cardiovascular health and disease 137
E.E.A. Egom
9. Statins in the treatment and prevention of cardiovascular diseases 155
C.H. Hennekens, E.H. Lieberman, M.H. Rubenstein, P.R. Hebert, D.L. DeMets and
M.A. Pfeffer
Handbook of cholesterol 7
Table of contents
Cholesterol: metabolism and health
10. Cholesterol content and health effects in free range, organic and conventionally raised
poultry and eggs 181
C. Wynn, T. Williams, O. Allen and P. Inserra
11. Cholesterol and fatty acid content and health effects in grass-fed and conventionally
raised grain-fed beef 191
P. Inserra, J.C. Shultz and C. Wynn
12. Some chronobiological investigations relevant to cholesterol 203
G. Cornelissen, R. Singh, R.K. Singh, R.B. Singh and F. de Meester
13. Cholesterol and the etiology of malaria 235
O.C. Obode, O.L. Erukainure, I.L. Eboagwu, D.N. Ibekwe, D.O. Akinyele, O. Oluwole
and G. Elemo
14. Familial hypercholesterolemia 243
L. Vladimirova-Kitova and S. Kitov
Structure and function of body organs
15. Cholesterol-containing foods for children and adolescents: recommendations catching
up with research 269
K.S. Kubena and W.A. McIntosh
16. The relationship between cholesterol metabolism and inflammation in chronic disease 297
C.J. Andersen, A. Doerr, K.E. Murphy and T. McNeely
17. Cellular cholesterol retention in atherosclerosis 317
H.I.H. El-Sayyad
18. Polyunsaturated fatty acids, cholesterol, triglycerides and cardiometabolic disease 335
B.S. Muhlhausler, and G.E. Leghi
19. Cholesterol: chemistry, cancer metabolism and tumorigenesis 355
O.L. Erukainure, A. Muhammad, E.E. Okoro, O.C. Obode, M.Z. Zaruwa and
G.N. Elemo
20. Bariatric surgery for modified cholesterol metabolism 367
A. Benetti, S.G. Garbossa and A.E. Pontiroli
8 Handbook of cholesterol
Table of contents
21. Why measuring cholesterol is obsolete and costly 375
P.J. Rosch
Cholesterol modification by dietary components
22. Egg yolk cholesterol and its functions in human health 399
E.D.N.S. Abeyrathne, S.M.C. Himali and D.U. Ahn
23. The eggs and cholesterol: a liability or an opportunity? 413
V. Guyonnet and H. Jing
24. Cholesterol and vitamin D: how the ‘mother’ and ‘daughter’ molecules interact 427
B. Nkooyeh and T.R. Neyestani
25. Antioxidant system regulation: from vitamins to vitagenes 451
P.F. Surai and V.I. Fisinin
Index 483
About the editors 493
Handbook of cholesterol 9