P1:OSO/OVY P2:OSO/OVY QC:OSO/OVY T1:OSO Printer:DRC GRBT294-FM GRBT294-Neinstein-v5.cls May8,2008 23:34 H A N D B O O K O F ADOLESCENT HEALTH CARE EDITOR-IN-CHIEF Lawrence S. Neinstein, MD, FACP ProfessorofPediatricsandMedicine ExecutiveDirector USCUniversityParkHealthCenter Chief,DivisionofCollegeHealth DepartmentofPediatrics USCKeckSchoolofMedicine AssociateDeanofStudentAffairs UniversityofSouthernCalifornia LosAngeles,California ASSOCIATEEDITORS Catherine M. Gordon, MD, MSc Debra K. Katzman, MD, FRCP(C) David S. Rosen, MD, MPH Elizabeth R. Woods, MD, MPH i P1:OSO/OVY P2:OSO/OVY QC:OSO/OVY T1:OSO Printer:DRC GRBT294-FM GRBT294-Neinstein-v5.cls May8,2008 23:34 AcquisitionsEditor:SonyaSeigafuse ManagingEditor:RyanShaw ProjectManager:RosanneHallowell ManufacturingManager:KathleenBrown MarketingManager:KimberlySchonberger DesignCoordinator:StephenDruding CoverDesigner:LarryDidona ProductionServices:Aptara(cid:2)R Copyright© 2009byLippincottWilliams&Wilkins,aWoltersKluwerbusiness 530WalnutStreet Philadelphia,PA19106 LWW.com Allrightsreserved.Thisbookisprotectedbycopyright.Nopartofthisbookmaybe reproducedinanyformorbyanymeans,includingphotocopying,orutilizingbyany informationstorageandretrievalsystemwithoutwrittenpermissionfromthecopyright owner,exceptforbriefquotationsembodiedincriticalarticlesandreviews. PrintedintheUnitedStates LibraryofCongressCataloging-in-PublicationData Handbookofadolescenthealthcare/editor-in-chief,LawrenceS.Neinstein; associateeditors,CatherineM.Gordon...[etal.]. p.;cm. Condensedversionof:AdolescentHealthCare/editor-in-chief,LawrenceS. Neinstein;associateeditors,CatherineM.Gordon...[etal.].5thed. c2008. Includesbibliographicalreferencesandindex. ISBN-13:978-0-7817-9020-8 ISBN-10:0-7817-9020-4 1.Adolescentmedicine—Handbooks,manuals,etc. 2.Teenagers—Healthand hygiene—Handbooks,manuals,etc. I.Neinstein,LawrenceS. II.AdolescentHealthCare. [DNLM:1. AdolescentMedicine—Handbooks. WS39H23412009] RJ550.H242009 616.00835—dc22 2008017783 Carehasbeentakentoconfirmtheaccuracyoftheinformationpresentedandtodescribe generallyacceptedpractices.However,theauthors,editors,andpublisherarenotresponsible forerrorsoromissionsorforanyconsequencesfromapplicationoftheinformationinthis bookandmakenowarranty,expressedorimplied,withrespecttothecurrency, completeness,oraccuracyofthecontentsofthepublication.Applicationofthisinformation inaparticularsituationremainstheprofessionalresponsibilityofthepractitioner. Theauthors,editors,andpublisherhaveexertedeveryefforttoensurethatdrugselection anddosagesetforthinthistextareinaccordancewithcurrentrecommendationsand practiceatthetimeofpublication.However,inviewofongoingresearch,changesin governmentregulations,andtheconstantflowofinformationrelatingtodrugtherapyand drugreactions,thereaderisurgedtocheckthepackageinsertforeachdrugforanychangein indicationsanddosageandforaddedwarningsandprecautions.Thisisparticularly importantwhentherecommendedagentisaneworinfrequentlyemployeddrug. SomedrugsandmedicaldevicespresentedinthispublicationhaveFoodandDrug Administration(FDA)clearanceforlimiteduseinrestrictedresearchsettings.Itisthe responsibilityofhealthcareproviderstoascertaintheFDAstatusofeachdrugordevice plannedforuseintheirclinicalpractice. Thepublishershavemadeeveryefforttotracecopyrightholdersforborrowedmaterial.If theyhaveinadvertentlyoverlookedany,theywillbepleasedtomakethenecessary arrangementsatthefirstopportunity. 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VisitLippincottWilliams&WilkinsontheInternet:atLWW.com.LippincottWilliams& Wilkinscustomerservicerepresentativesareavailablefrom8:30amto6pm,EST. 10 9 8 7 6 5 4 3 2 1 ii P1:OSO/OVY P2:OSO/OVY QC:OSO/OVY T1:OSO Printer:DRC GRBT294-FM GRBT294-Neinstein-v5.cls May8,2008 23:34 To my incredible family My wife, Debra; My children, Yael and Yossi, Aaron, and David; My granddaughter, Bella; My parents, Shirley, Roz, and Ben; and in memory of my father, Alvin iii P1:OSO/OVY P2:OSO/OVY QC:OSO/OVY T1:OSO Printer:DRC GRBT294-FM GRBT294-Neinstein-v5.cls May8,2008 23:34 iv P1:OSO/OVY P2:OSO/OVY QC:OSO/OVY T1:OSO Printer:DRC GRBT294-FM GRBT294-Neinstein-v5.cls May8,2008 23:34 C O N T E N T S Contributors xiii Foreword xxiv Preface xxvi Acknowledgments xxvii SECTION I: GENERAL CONSIDERATIONS IN ADOLESCENT CARE CHAPTER 1 NormalPhysicalGrowthandDevelopment 1 JEREMIM.CARSWELLANDDIANEE.J.STAFFORD CHAPTER 2 PsychosocialDevelopmentinNormal Adolescents 14 MARIRADZIK,SARASHERER,ANDLAWRENCES.NEINSTEIN CHAPTER 3 OfficeVisit,InterviewTechniques,and RecommendationstoParents 18 ELIZABETHR.WOODSANDLAWRENCES.NEINSTEIN CHAPTER 4 PreventiveHealthCareforAdolescents 25 DAVIDS.ROSENANDLAWRENCES.NEINSTEIN CHAPTER 5 VitalStatisticsandInjuries 46 PONRATPAKPREO,JONATHAND.KLEIN,AND LAWRENCES.NEINSTEIN CHAPTER 6 Nutrition 66 MICHAELR.KOHN CHAPTER 7 UnderstandingLegalAspectsofCare 74 ABIGAILENGLISH SECTION II: ENDOCRINE PROBLEMS CHAPTER 8 AbnormalGrowthandDevelopment 79 JOANM.MANSFIELDANDLAWRENCES.NEINSTEIN CHAPTER 9 ThyroidDiseaseinAdolescents 90 STEPHENALBERTHUANGANDLAWRENCES.NEINSTEIN CHAPTER 10 DiabetesMellitus 100 DONALDP.ORR CHAPTER 11 Gynecomastia 108 ALAINJOFFE v P1:OSO/OVY P2:OSO/OVY QC:OSO/OVY T1:OSO Printer:DRC GRBT294-FM GRBT294-Neinstein-v5.cls May8,2008 23:34 vi CONTENTS SECTION III: CARDIOVASCULAR PROBLEMS CHAPTER 12 CardiacRiskFactorsandHyperlipidemia 113 MARCS.JACOBSON,MICHAELR.KOHN,AND LAWRENCES.NEINSTEIN CHAPTER 13 SystemicHypertension 126 JOSEPHT.FLYNN CHAPTER 14 HeartMurmursandMitralValveProlapse 138 AMYD.DIVASTAANDMARKE.ALEXANDER SECTION IV: ORTHOPEDIC PROBLEMS CHAPTER 15 ScoliosisandKyphosis 147 MATTHEWJ.BUECHE CHAPTER 16 CommonOrthopedicProblems 152 KEITHJ.LOUDANDROBERTJ.BIELSKI CHAPTER 17 BackPainintheAdolescent 161 JORDAND.METZLANDLAWRENCES.NEINSTEIN CHAPTER 18 GuidelinesforPhysicalActivityand SportsParticipation 169 KEITHJ.LOUDANDALBERTC.HERGENROEDER SECTION V: DERMATOLOGIC DISORDERS CHAPTER 19 Acne 189 MEI-LINT.PANGANDLAWRENCEF.EICHENFIELD CHAPTER 20 MiscellaneousDermatologicDisorders 199 MEI-LINT.PANGANDLAWRENCEF.EICHENFIELD SECTION VI: NEUROLOGIC DISORDERS CHAPTER 21 Epilepsy 215 WENDYG.MITCHELL,ARTHURPARTIKIAN,AND LAWRENCES.NEINSTEIN CHAPTER 22 Headaches 230 WENDYG.MITCHELL,KIARASHSADRIEH,AND LAWRENCES.NEINSTEIN CHAPTER 23 SyncopeandSuddenCardiacDeath 238 AMYD.DIVASTA,WENDYG.MITCHELL,AND MARKE.ALEXANDER P1:OSO/OVY P2:OSO/OVY QC:OSO/OVY T1:OSO Printer:DRC GRBT294-FM GRBT294-Neinstein-v5.cls May8,2008 23:34 CONTENTS vii CHAPTER 24 SleepDisorders 245 SHELLYK.WEISS SECTION VII: GENITOURINARY DISORDERS CHAPTER 25 GenitourinaryTractInfections 251 LAWRENCEJ.D’ANGELOANDLAWRENCES.NEINSTEIN CHAPTER 26 Enuresis 259 DIANETANAKA CHAPTER 27 AsymptomaticProteinuriaandHematuria 264 LAWRENCEJ.D’ANGELOANDLAWRENCES.NEINSTEIN CHAPTER 28 ScrotalDisorders 270 WILLIAMP.ADELMANANDALAINJOFFE SECTION VIII: INFECTIOUS DISEASES CHAPTER 29 InfectiousRespiratoryIllnesses 279 TERRILLBRAVENDERANDEMMANUELWALTER CHAPTER 30 Hepatitis 289 PRAVEENS.GODAY CHAPTER 31 HumanImmunodeficiencyVirusInfectionsand AcquiredImmunodeficiencySyndrome 301 MARVINE.BELZER,MIGUELMARTINEZ,AND LAWRENCES.NEINSTEIN SECTION IX: CONDITIONS AFFECTING NUTRITION AND WEIGHT CHAPTER 32 Obesity 313 MARCIESCHNEIDER CHAPTER 33 AnorexiaNervosaandBulimiaNervosa 321 DEBRAK.KATZMANANDNEVILLEH.GOLDEN SECTION X: PSYCHOSOMATIC ILLNESSES AND OTHER MEDICAL DISORDERS CHAPTER 34 PsychosomaticIllnessinAdolescents 333 DAVIDM.SIEGEL CHAPTER 35 FatigueandtheChronicFatigueSyndrome 337 MARTINFISHER P1:OSO/OVY P2:OSO/OVY QC:OSO/OVY T1:OSO Printer:DRC GRBT294-FM GRBT294-Neinstein-v5.cls May8,2008 23:34 viii CONTENTS CHAPTER 36 ChronicAbdominalPain 342 PAULAK.BRAVERMAN CHAPTER 37 ChestPain 347 JOHNKULIGANDLAWRENCES.NEINSTEIN CHAPTER 38 FibromyalgiaSyndromeandReflex SympatheticDystrophy 351 DAVIDM.SIEGEL SECTION XI: SEXUALITY AND CONTRACEPTION CHAPTER 39 AdolescentSexuality 357 MARTINM.ANDERSONANDLAWRENCES.NEINSTEIN CHAPTER 40 Gay,Lesbian,Bisexual,andTransgender Adolescents 370 ERICMEININGERANDGARYREMAFEDI CHAPTER 41 TeenagePregnancy 377 JOANNEE.COX CHAPTER 42 Contraception 389 ANITAL.NELSONANDLAWRENCES.NEINSTEIN CHAPTER 43 CombinationHormonalContraceptives 403 ANITAL.NELSONANDLAWRENCES.NEINSTEIN CHAPTER 44 IntrauterineContraception 418 PATRICIAA.LOHR CHAPTER 45 BarrierContraceptivesandSpermicides 423 PATRICIAA.LOHR CHAPTER 46 EmergencyContraception 434 LISAJOHNSONANDMELANIEA.GOLD CHAPTER 47 Long-ActingProgestins 439 ANITAL.NELSON SECTION XII: ADOLESCENT GYNECOLOGY CHAPTER 48 GynecologicalExaminationoftheAdolescent Female 451 MERRILLWEITZELANDJEANS.EMANS CHAPTER 49 NormalMenstrualPhysiology 457 SARIL.KIVESANDJUDITHA.LACY P1:OSO/OVY P2:OSO/OVY QC:OSO/OVY T1:OSO Printer:DRC GRBT294-FM GRBT294-Neinstein-v5.cls May8,2008 23:34 CONTENTS ix CHAPTER 50 DysmenorrheaandPremenstrualSyndrome 460 PAULAK.BRAVERMAN CHAPTER 51 DysfunctionalUterineBleeding 467 LAURIEA.P.MITANANDGAILB.SLAP CHAPTER 52 MenstrualDisorders:Amenorrheaand PolycysticOvarySyndrome 470 AMYFLEISCHMAN,CATHERINEM.GORDON,AND LAWRENCES.NEINSTEIN CHAPTER 53 PelvicMasses 479 PAULAJ.ADAMSHILLARD CHAPTER 54 PapSmearsandAbnormalCervicalCytology 484 ANNA-BARBARAMOSCICKI CHAPTER 55 VaginitisandVaginosis 491 LORISY.HWANGANDMARY-ANNSHAFER CHAPTER 56 EctopicPregnancyandOtherComplications ofPregnancy 499 MELISSAD.MIROSHANDMARYANNEJAMIESON CHAPTER 57 Galactorrhea 506 NORMANP.SPACKANDSANDRALOEBSALSBERG CHAPTER 58 HirsutismandVirilization 509 CATHERINEM.GORDONANDLAWRENCES.NEINSTEIN CHAPTER 59 AdolescentBreastDisorders 513 HEATHERR.MACDONALD SECTION XIII: SEXUALLY TRANSMITTED DISEASES CHAPTER 60 OverviewofSexuallyTransmittedDiseases 521 J.DENNISFORTENBERRYANDLAWRENCES.NEINSTEIN CHAPTER 61 Gonorrhea 547 MARGARETJ.BLYTHE CHAPTER 62 ChlamydiaTrachomatis 556 CATHERINEMILLERANDMARY-ANNSHAFER CHAPTER 63 PelvicInflammatoryDisease 564 LYDIAA.SHRIER CHAPTER 64 Syphilis 569 J.DENNISFORTENBERRYANDLAWRENCES.NEINSTEIN P1:OSO/OVY P2:OSO/OVY QC:OSO/OVY T1:OSO Printer:DRC GRBT294-FM GRBT294-Neinstein-v5.cls May8,2008 23:34 x CONTENTS CHAPTER 65 HerpesGenitalis 575 GALER.BURSTEINANDKIMBERLYA.WORKOWSKI CHAPTER 66 HumanPapillomavirusInfectionand AnogenitalWarts 580 JESSICAA.KAHN CHAPTER 67 OtherSexuallyTransmittedDiseasesIncluding GenitalUlcers,Pediculosis,Scabiesand Molluscum 584 WENDIG.EHRMAN,M.SUSANJAY,ANDLAWRENCES.NEINSTEIN SECTION XIV: DRUG USE AND ABUSE CHAPTER 68 AdolescentSubstanceUseandAbuse 593 ROBERTE.MORRISANDALAINJOFFE CHAPTER 69 Alcohol 601 MARTINM.ANDERSONANDLAWRENCES.NEINSTEIN CHAPTER 70 Tobacco 608 SETHD.AMMERMAN CHAPTER 71 PsychoactiveSubstancesofAbuseUsedby Adolescents 622 SHARONLEVYANDALAND.WOOLF CHAPTER 72 LaboratoryTestingforPsychoactive SubstancesofAbuse 652 SHARONLEVYANDJOHNR.KNIGHT CHAPTER 73 Office-BasedManagementofAdolescent SubstanceUseandAbuse 661 SHARONLEVYANDJOHNR.KNIGHT CHAPTER 74 IntensiveDrugTreatment 671 BRIGIDL.VAUGHANANDJOHNR.KNIGHT SECTION XV: PSYCHOSOCIAL PROBLEMS AND CONCERNS CHAPTER 75 CommonConcernsofAdolescentsandTheir Parents 677 MARIRADZIK,SARASHERER,ANDLAWRENCES.NEINSTEIN CHAPTER 76 High-RiskandDelinquentBehavior 681 ROBERTE.MORRISANDRALPHJ.DICLEMENTE