Growth Factors and their Receptors in Cancer Metastasis

309 Pages·2001·13.624 MB·English

by  Farhad Ravandi, Zeev Estrov (auth.), C. R. Snyder, Wen G. Jiang, Kunio Matsumoto, Toshikazu Nakamura (eds.)

Growth Factors and their Receptors in Cancer Metastasis
Cancer Metastasis – Biology and Treatment
VOLUME 2
Series Editors
Richard J. Ablin, Innapharma, Inc., Parkridge, U.S.A.
Wen G. Jiang, University of Wales College of Medicine, Cardiff, U.K.
Advisory Editorial Board
Harold F. Dvorak
Phil Gold
Ian R. Hart
Hiroshi Kobayashi
Robert E. Mansel
Marc Mareel
Growth Factors and
their Receptors in
Cancer Metastasis
Edited by
Wen G. Jiang
University of Wales College of Medicine,
Cardiff, The United Kingdom
Kunio Matsumoto
University of Osaka Medical School,
Osaka, Japan
and
Toshikazu Nakamura
University of Osaka Medical School,
Osaka, Japan
KLUWER ACADEMIC PUBLISHERS
NEW YORK,BOSTON, DORDRECHT, LONDON, MOSCOW
eBookISBN: 0-306-48399-8
Print ISBN: 0-7923-7141-0
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Table of Contents
Contributors vii
The Role of Leukemia Inhibitory Factor in Cancer and Cancer
Metastasis 1
FARHAD RAVANDI AND ZEEV ESTROV
Interleukin-2 and Its Receptors in Human Solid Tumours:
Immunobiology and Clinical Significance 27
THERESA L. WHITESIDE, TORSTEN E. REICHERT, AND QING PING DOU.
Interleukin-8 and Angiogenesis 51
TRACEY A. MARTIN.
The Role of Interleukin-11 in the Formation of Bone Metastases. 67
NAOYA FUJITA AND TAKASHI TSURUO.
Therapeutic Potential of Adenovirus Mediated Interleukin-12 Gene
Therapy for Prostate Cancer 79
SHIN EBARA, YASUTOMONASU, TAKEFUMI SATOH, SATORU SHIMURA,
CHRIS H. BANGMA, GERALD W. HULL, MARK A. MCCURDY, JIANXIANG
WANG,GUANG YANG, TERRY L. TIMME, AND TIMOTHY C. THOMPSON.
Fibroblast Growth Factors and Their Receptors in Metastases of
Prostate and Other Urological Cancers 93
ZORAN CULIG, MARCUS V. CRONAUER, ALFRED HOBISCH, GEORG
BARTSCH AND HELMUT KLOCKER.
vi Table of Contents
Insulin-Like Growth Factor Axis Elements in Breast Cancer
Progression 107
EMILIA MIRA, ROSA ANA LACALLE, CARLOS MARTÍNEZ-A. AND
SANTOS MAÑES.
The Role of Platelet Derived Growth Factor (PDGF) and Its
Receptors in Cancer and Metastasis 167
SARA WEISS FEIGELSON, CHERYL FITZER-ATTAS, LEA EISENBACH.
TGF receptor Signaling in Cancer and Metastasis 187
MARTINOFT.
VEGF-C/VEGFRS and Cancer Metastasis 223
YUTAKA YONEMURA, YOSHIO ENDOU, TAKUMA SASAKI, KAZUO
SUGIYAMA, TETUMOURI YAMASHIMA, TAINA PARTANEN, KARI
ALITALO.
HGF-c-met receptor Pathway in Tumor Invasion-Metastasis and
Potential Cancer Treatment with NK4 241
KUNIO MATSUMOTO AND TOSHIKAZU NAKAMURA.
Growth Factor Receptors and Cell Adhesion Complexes in
Cytoskeletal Assembly/Anchorage 277
GAYNOR DAVIES, MALCOLM D. MASON AND WEN G. JIANG
Index 291
vii
Contributors
Alitalo, Kari. Molecular/Cancer Biology Laboratory, Haatman Institute,
University of Helsinki, PL 21, 00014 Helsinki, Finland
Bangma, Chris H. Scott Department of Urology, Baylor College of
Medicine, Houston, Texas, USA
Bartsch, Georg. Department of Urology, University of Innsbruck,
Anichstrasse 35, A-6020 Innsbruck, Austria
Cronauer, Marcus V. Department of Urology, University of Innsbruck,
Anichstrasse 35, A-6020 Innsbruck, Austria
Culig, Zoran. Department of Urology, University of Innsbruck,
Anichstrasse 35, A-6020 Innsbruck, Austria
Davies, Gaynor. Metastasis Research Group, University Department of
Surgery, University of Wales College of Medicine, Heath Park, Cardiff,
CF14 4XN.UK.
Dou, Qing Ping. H. Lee Moffitt Cancer Center & Research Institute,
Tampa, FL 33612, USA
Ebara, Shin. Scott Department of Urology, Baylor College of
Medicine, Houston, Texas, USA
Eisenbach, Lea. Weizmann Institute of Science, Department of
Immunology, Rehovot, Israel
Endou, Yoshio. Experimental Therapeutics Cancer Research Institute,
Kanazawa University, Takara-Machi 13-1, Kanazawa 920, Japan
Estrov, Zeev. Department of Bioimmunotherapy, The University of
Texas, M. D. Anderson Cancer Center, Houston, Texas, U.S.A
viii Contributors
Feigelson, Sara Weiss. Weizmann Institute of Science, Department of
Immunology, Rehovot, Israel
Fitzer-Attas, Cheryl. Weizmann Institute of Science, Department of
Immunology, Rehovot, Israel
Fujita, Naoya. Institute of Molecular and Cellular Biosciences,
University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan
Hobisch, Alfred. Department of Urology, University of Innsbruck,
Anichstrasse 35, A-6020 Innsbruck, Austria
Hull, Gerald W. Scott Department of Urology, Baylor College of
Medicine, Houston, Texas, USA
Jiang, Wen G. Metastasis Research Group, University Department of
Surgery, University of Wales College of Medicine, Heath Park, Cardiff,
CF14 4XN, UK.
Klocker, Helmut. Department of Urology, University of Innsbruck,
Anichstrasse 35, A-6020 Innsbruck, Austria
Lacalle, Rosa Ana. Department of Immunology and Oncology, Centro
Nacional de Biotecnología-CSIC, Campus de Cantoblanco, Universidad
Autónoma de Madrid, E-28049 Madrid, Spain.
Mañes, Santos. Department of Immunology and Oncology, Centro
Nacional de Biotecnología-CSIC, Campus de Cantoblanco, Universidad
Autónoma de Madrid, E-28049 Madrid, Spain.
Martínez, Carlos. Department of Immunology and Oncology, Centro
Nacional de Biotecnología-CSIC, Campus de Cantoblanco, Universidad
Autónoma de Madrid, E-28049 Madrid, Spain.
Mason, Malcolm D. Department of Medicine, Section of Clinical
Oncology, Velindre Hospital, Cardiff, CF4 7XL. UK
Martin, Tracey A. Metastasis Research Group, University Department
of Surgery, University of Wales College of Medicine, Heath Park, Cardiff,
CF14 4XN. UK.
Matsumoto, Kunio. Division of Biochemistry, Department of
Oncology, Biomedical Research Center, Osaka University Graduate School
of Medicine, Suita, Osaka 565-0871, Japan
McCurdy, Mark A. Scott Department of Urology, Baylor College of
Medicine, Houston, Texas, USA
Contributors ix
Mira, Emilia. Department of Immunology and Oncology, Centro
Nacional de Biotecnología-CSIC, Campus de Cantoblanco, Universidad
Autónoma de Madrid, E-28049 Madrid, Spam.
Nakamura, Toshikazu. Division of Biochemistry, Department of
Oncology, Biomedical Research Center, Osaka University Graduate School
of Medicine, Suita, Osaka 565-0871, Japan
Nasu, Yasutomo. Scott Department of Urology, Baylor College of
Medicine, Houston, Texas, USA
Oft, Martin. UCSF Cancer Center - Box 0875, University of California,
San Francisco, 2340 Sutter Street, Room S271, San Francisco, CA 94143-
0128, USA
Partanen, Taina. Molecular/Cancer Biology Laboratory, Haatman
Institute, University of Helsinki, PL 21, 00014 Helsinki, Finland
Ravandi, Farhad. Department of Bioimmunotherapy, The University
of Texas, M. D. Anderson Cancer Center, Houston, Texas, U.S. A
Reichert, Torsten E. University of Mainz, Mainz, Germany
Sasaki, Takuma. Experimental Therapeutics Cancer Research Institute,
KanazawaUniversity, Takara-Machi 13-1, Kanazawa 920, Japan
Satoh, Takefumi. Scott Department of Urology, Baylor College of
Medicine, Houston, Texas, USA
Shimura, Satoru. Scott Department of Urology, Baylor College of
Medicine, Houston, Texas, USA
Sugiyama, Kazuo. Virology Division, National Cancer Center Research
Institute, 5-1-1 Tsukiji, Chuoo-Ku, Tokyo 104, Japan
Thompson, Timothy C. Scott Department of Urology, Cell Biology
and Radiology, Baylor College of Medicine, Houston, Texas, USA
Timme, Terry L. Scott Department of Urology, Baylor College of
Medicine, Houston, Texas, USA
Tsuruo, Takashi. Institute of Molecular and Cellular Biosciences,
University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan
Wang, Jianxiang G. Scott Department of Urology, Baylor College of
Medicine, Houston, Texas, USA
Wang Yang, Guang. Scott Department of Urology, Baylor College of
Medicine, Houston, Texas, USA
x Contributors
Whiteside, Theresa L. University of Pittsburgh Cancer Institute,
Pittsburgh, PA 15213, USA
Yamashima, Tetumori. Department of Neurosurgery, School of
Medicine, Kanazawa University, Takara-Machi 13-1, Kanazawa 920, Japan
Yonemura, Yutaka. Second Department of Surgery, School of
Medicine, Kanazawa University, Takara-Machi 13-1, Kanazawa 920, Japan