Green’s Child and Adolescent Clinical Psychopharmacology PDF
Preview Green’s Child and Adolescent Clinical Psychopharmacology
Green’s Child and adolesCent CliniCal PsyChoPharmaColoGy (c) 2014 Wolters Kluwer. All Rights Reserved. Green’S Child and adoleSCent CliniCal PSyChoPharmaColoGy 5TH EDITION William m. KlyKylo, am, mD chRistina Weston, mD Professor and Director Associate Professor Division of Child and Adolescent Psychiatry Division of Child and Adolescent Psychiatry Wright State University Boonshoft Wright State University Boonshoft School of Medicine School of Medicine Dayton, Ohio Dayton, Ohio RicK BoWeRs, mD Julia JacKson, mD Clinical Associate Professor Assistant Professor Division of Child and Adolescent Psychiatry Division of Child and Adolescent Psychiatry Wright State University Boonshoft Wright State University Boonshoft School of Medicine School of Medicine Dayton, Ohio Dayton, Ohio (c) 2014 Wolters Kluwer. All Rights Reserved. Acquisitions Editor: Julie Goolsby Product Manager: Tom Gibbons Vendor Manager: Alicia Jackson Senior Manufacturing Manager: Beth Welsh Marketing Manager: Alexander Burns Design Coordinator: Steve Druding Production Service: S4Carlisle Publishing Services © 2014 by Lippincott WiLLiams & WiLkins, a WoLters kLuWer business two commerce square 2001 market street philadelphia, pa 19103 usa LWW.com © 2007, 2001 by Lippincott Williams & Wilkins, a Wolters Kluwer business. Copyright © 1995, 1991 by Williams & Wilkins. All rights reserved. This book is protected by copyright. No part of this book may be reproduced in any form by any means, including photocopying, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. Printed in China Library of congress cataloging-in-publication Data Klykylo, William M., author. Green’s child and adolescent clinical psychopharmacology / William M. Klykylo.—Fifth edition. p. ; cm. Child and adolescent clinical psychopharmacology Preceded by Child and adolescent clinical psychopharmacology / Wayne Hugo Green. 4th ed. c2007. Includes bibliographical references and index. ISBN 978-1-4511-0714-2—ISBN 1-4511-0714-5 I. Green, Wayne H. Child and adolescent clinical psychopharmacology. Preceded by (work): II. Title. III. Title: Child and adolescent clinical psychopharmacology. [DNLM: 1. Mental Disorders—drug therapy. 2. Adolescent. 3. Child. 4. Psychopharmacology— methods. 5. Psychotropic Drugs—therapeutic use. WS 350.2] RC483 616.89'18—dc23 2013018393 Care has been taken to confirm the accuracy of the information presented and to describe gener- ally accepted practices. However, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, expressed or implied, with respect to the currency, completeness, or accuracy of the con- tents of the publication. Application of the information in a particular situation remains the profes- sional responsibility of the practitioner. The authors, editors, and publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accordance with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new or infrequently employed drug. Some drugs and medical devices presented in the publication have Food and Drug Administration (FDA) clearance for limited use in restricted research settings. It is the responsibility of the health care provider to ascertain the FDA status of each drug or device planned for use in their clinical practice. To purchase additional copies of this book, call our customer service department at (800) 638-3030 or fax orders to (301) 223-2320. International customers should call (301) 223-2300. Visit Lippincott Williams & Wilkins on the Internet: at LWW.com. Lippincott Williams & Wilkins customer service representatives are available from 8:30 am to 6:00 pm, EST. 10 9 8 7 6 5 4 3 2 1 (c) 2014 Wolters Kluwer. All Rights Reserved. To our teachers, our students, our patients, and our families, and to Wayne Hugo Green (c) 2014 Wolters Kluwer. All Rights Reserved. Contributor Ryan Mast, MBA, DO Assistant Professor Division of Child and Adolescent Psychiatry Wright State University Boonshoft School of Medicine Dayton, Ohio vii (c) 2014 Wolters Kluwer. All Rights Reserved. Preface It has been both a great honor and a daunting challenge to prepare a fifth edition of Wayne Hugo Green’s seminal Child and Adolescent Clinical Psychopharmacology. Words cannot express our respect for Dr. Green’s magnum opus; perhaps it is best demonstrated by our efforts as four editors to revisit what Dr. Green has done by himself through four editions. This book has exerted a major beneficial influence on the conduct of our specialty and the care of our patients, and we have endeav- ored to be worthy of this tradition. We have maintained Dr. Green’s attention to FDA Black Box and Bold Print warnings, as increasing evidence appears that modern psychopharmacology, de- spite its great benefits, is no more exempt from adversity than other medical in- terventions. Modern agents are not without undesirable effects in some cases, and they are never panaceas or replacements for psychosocial and educational inter- ventions. The possibility of misadventure becomes increasingly apparent as more of these agents are administered to more children. At the same time, however, the increasing use of these medications is also an indication of their utility and promise to children. We have approached this book as we approach our clinical work, with optimism balanced by realistic expectations and clinical caution. The general format of this book has been carried on from previous editions, but with some modifications. Notably, drugs used to enhance attentional function are now grouped together. A number of older drugs that are less commonly used today are covered in an appendix. We have done this in the interest of utility and not as a disparagement of the continued value and frequent cost-effectiveness of these agents for some patients. We have included mention of thioridazine not as endorsement but in recognition of the use of that agent by a few practitioners. Since the last edition, there has been an increase in the number of extended-release psychostimulant preparations and of new second-generation antipsychotic drugs, and these are noted herein. Child and adolescent psychopharmacology has largely been conducted on an “off-label” basis, but with evolving research, an increasing number of indications for specific drugs have been approved by the FDA, and we have recognized these. Inevitably, indications (and possible contraindications) will continue to appear after any book goes to print, and the reader is strongly encour- aged to maintain currency with www.fda.gov and related sources. Finally, in view of the growing recognition of the moral as well as legal challenges related to the use of psychotropic medication in minors, we have added a section on the ethics of psychopharmacology. ix (c) 2014 Wolters Kluwer. All Rights Reserved. x Preface We hope that this edition will continue the book’s tradition of authority and utility. Whatever its merits, preparing it required the help of many others. Dr. Green has been personally supportive, and we would not have undertaken this project without his kind encouragement. The staff of Lippincott Williams & Wilkins, most notably Tom Gibbons, have made our work pleasurable through their encour- agement, advice, and patience. Here at Wright State University, Megan Schwartz assisted with research and Elizabeth Huber employed her very considerable edito- rial abilities in organizing our texts and references. No such work as this could ever come about without the assistance of our colleagues and the tolerance of our families, to whom we are forever in debt. WMK, RB, CGW, JJ (c) 2014 Wolters Kluwer. All Rights Reserved.
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