107 Advances in Biochemical Engineering/Biotechnology SeriesEditor:T.Scheper EditorialBoard: W.Babel·I.Endo·S.-O.Enfors·A.Fiechter·M.Hoare·W.-S.Hu B.Mattiasson·J.Nielsen·H.Sahm·K.Schügerl·G.Stephanopoulos U.vonStockar·G.T.Tsao·C.Wandrey·J.-J.Zhong AdvancesinBiochemicalEngineering/Biotechnology SeriesEditor:T.Scheper RecentlyPublishedandForthcoming Volumes GreenGeneTechnology MarineBiotechnologyI ResearchinanAreaofSocialConflict VolumeEditors:LeGal,Y.,Ulber,R. VolumeEditors:Fiechter,A.,Sautter,C. Vol.96,2005 Vol.107,2007 MicroscopyTechniques WhiteBiotechnology VolumeEditor:Rietdorf,J. VolumeEditors:Ulber,R.,Sell,D. Vol.95,2005 Vol.105,2007 RegenerativeMedicineII AnalyticsofProtein-DNAInteractions ClinicalandPreclinicalApplications VolumeEditor:Seitz,H. VolumeEditor:Yannas,I.V. Vol.104,2007 Vol.94,2005 TissueEngineeringII RegenerativeMedicineI BasicsofTissueEngineeringandTissue Theories,ModelsandMethods Applications VolumeEditor:Yannas,I.V. VolumeEditors:Lee,K.,Kaplan,D. 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SpringerWWWhomepage:springer.com VisittheABEcontentatspringerlink.com LibraryofCongressControlNumber:2007922570 ISSN0724-6145 ISBN978-3-540-71321-0SpringerBerlinHeidelbergNewYork DOI10.1007/978-3-540-71323-4 Thisworkissubjecttocopyright.Allrightsarereserved,whetherthewholeorpartofthematerial isconcerned,specificallytherightsoftranslation,reprinting,reuseofillustrations,recitation,broad- casting,reproductiononmicrofilmorinanyotherway,andstorageindatabanks.Duplicationof thispublicationorpartsthereofispermittedonlyundertheprovisionsoftheGermanCopyrightLaw ofSeptember9,1965,initscurrentversion,andpermissionforusemustalwaysbeobtainedfrom Springer.ViolationsareliableforprosecutionundertheGermanCopyrightLaw. 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Coverdesign:WMXDesignGmbH,Heidelberg TypesettingandProduction:LE-TEXJelonek,Schmidt&VöcklerGbR,Leipzig Printedonacid-freepaper 02/3180YL–543210 SeriesEditor Prof.Dr.T.Scheper InstituteofTechnicalChemistry UniversityofHannover Callinstraße3 30167Hannover,Germany [email protected] VolumeEditors Prof.Dr.ArminFiechter PDDr.ChristofSautter InstituteofBiotechnology InstituteofPlantScience, EidgenössischeTechnischeHochschule SwissFederalInstituteofTechnologyZurich ETH-Hönggerberg Universitätsstr.2 8093Zürich,Switzerland 8092Zürich,Switzerland ae.fi[email protected] [email protected] EditorialBoard Prof.Dr.W.Babel Prof.Dr.M.Hoare SectionofEnvironmentalMicrobiology DepartmentofBiochemicalEngineering Leipzig-HalleGmbH UniversityCollegeLondon Permoserstraße15 TorringtonPlace 04318Leipzig,Germany London,WC1E7JE,UK [email protected] [email protected] Prof.Dr.S.-O.Enfors Prof.Dr.I.Endo DepartmentofBiochemistryand SaitamaIndustrialTechnologyCenter Biotechnology 3-12-18,KamiaokiKawaguchi-shi RoyalInstituteofTechnology Saitama,333-0844,Japan Teknikringen34, [email protected] 10044Stockholm,Sweden [email protected] Prof.Dr.A.Fiechter InstituteofBiotechnology EidgenössischeTechnischeHochschule ETH-Hönggerberg 8093Zürich,Switzerland ae.fi[email protected] VI EditorialBoard Prof.Dr.W.-S.Hu Prof.Dr.J.Nielsen ChemicalEngineering CenterforProcessBiotechnology andMaterialsScience TechnicalUniversityofDenmark UniversityofMinnesota Building223 421WashingtonAvenueSE 2800Lyngby,Denmark Minneapolis,MN55455-0132,USA [email protected] [email protected] Prof.Dr.K.Schügerl Prof.Dr.B.Mattiasson InstituteofTechnicalChemistry DepartmentofBiotechnology UniversityofHannover,Callinstraße3 ChemicalCenter,LundUniversity 30167Hannover,Germany P.O.Box124,22100Lund,Sweden [email protected] [email protected] Prof.Dr.U.vonStockar Prof.Dr.H.Sahm LaboratoiredeGénieChimiqueet InstituteofBiotechnolgy Biologique(LGCB),DépartmentdeChimie ForschungszentrumJülichGmbH SwissFederalInstitute 52425Jülich,Germany ofTechnologyLausanne [email protected] 1015Lausanne,Switzerland urs.vonstockar@epfl.ch Prof.Dr.G.Stephanopoulos DepartmentofChemicalEngineering Prof.Dr.C.Wandrey MassachusettsInstituteofTechnology InstituteofBiotechnology Cambridge,MA02139-4307,USA ForschungszentrumJülichGmbH [email protected] 52425Jülich,Germany [email protected] Prof.Dr.G.T.Tsao ProfessorEmeritus PurdueUniversity WestLafayette,IN47907,USA [email protected] [email protected] Prof.Dr.J.-J.Zhong Bio-Building#3-311 CollegeofLifeScience&Biotechnology KeyLaboratoryofMicrobialMetabolism, MinistryofEducation ShanghaiJiaoTongUniversity 800Dong-ChuanRoad Minhang,Shanghai200240,China [email protected] AdvancesinBiochemicalEngineering/Biotechnology AlsoAvailableElectronically For all customers who have a standing order to Advances in Biochemical Engineering/Biotechnology, we offerthe electronic version via SpringerLink freeofcharge.Pleasecontactyourlibrarianwhocanreceiveapasswordorfree accesstothefullarticlesbyregisteringat: springerlink.com Ifyoudonothaveasubscription,youcanstillviewthetablesofcontentsofthe volumesandtheabstractofeacharticlebygoingtotheSpringerLinkHome- page,clickingon“BrowsebyOnlineLibraries”,then“ChemicalSciences”,and finallychooseAdvancesinBiochemicalEngineering/Biotechnology. 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Preface Greengenetechnology(GGT),understoodasapartofmodernbiotechnology, has been on a steady, triumphal progression over the last ten years (ISAAA 2007,seethecontributionbyEinseleinthisissue).Thisvolume,jointlyedited byProf.Fiechterandme,dealswithsomeactualscientificandsocio-economic aspects with regard to genetically modified plants (GMP). Worldwide more than 100 million hectares of agronomicalland are covered by GMP. This in- cludes some prominent industrialised Western countries like the USA and Canada,aseriesofthresholdcountrieslikeArgentina,Brazil,IndiaandChina, andanumber ofdeveloping countries. Clearly, someofthesecountrieshave todealwithcropplantproductionandhumannutritioninaverypragmatic waysince,forexample, Indiahastofeedabouta1/5oftheworldpopulation on about 3% of the arable land. In contrast, the situation in Europe appears verydifferent. Foodsupply ismorethansufficient andcomparablyinexpen- sive. This surplus of food is on one hand convenient, since starvation has beenlargelyunknowninEuropeforabout50years,withonlycomparatively fewexceptionsofsociallyperipheralindividuals. Ontheotherhanditmakes thepopulationcarelessaboutthefuturefoodsupply.Evenbeyondmerefood supply,Europegaineditsculturalvaluesfromitsagriculturalsuccessoverthe centuries.Asinglefarmerbecameabletofeedmoreandmorepeoplemaking themfreetoworkoutsideofagricultureasacraftsman,artist,poet,scientist, engineer,mayor,administrativeofficial,priest,philosopher,orsoldier–togive onlyafewexamples.Inthepublicperceptionthisconnectionbetweenagron- omyandculturalwelfareisnotsufficientlyappreciatedinEurope.Switzerland, geographicallyin the centre ofEurope (although not a member of the polit- ical union) has the same cultural tradition, only somewhat shifted towards themoreconservativemoodcommontomountainpopulations.Insummary, amajorityofEuropeans,andtheSwisspopulationinparticular,arereluctant tonewmethodsinagronomy. Switzerlandisprobablytheonlycountryworldwidethathasamoratorium onthecommercialgrowthofgeneticallymodifiedplantsinitsconstitution.In contrast,themoratoriumforGMPintheEuropeanUnionbetween 1999and 2004 was not legally binding. In Switzerland it was thepopulation itself that establishedthismoratoriumintofundamentallawbymeansofareferendum. Moreover,allSwisslegislationaboutgenetechnology,theso-called“Genlex”,
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