Golwalla’s Medicine for Students PDF
Preview Golwalla’s Medicine for Students
mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com Golwalla’s MEDICINE for Students mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com Golwalla’s MEDICINE for Students A Reference Book for the Family Physician Twenty-Fifth Edition ASPI F GOLWALLA MD FACC FCPS FCCP Emeritus Professor of Medicine Seth GS Medical College and KEM Hospital Mumbai, Maharashtra, India SHARUKH A GOLWALLA MD (Med) DM (Card) FCCP Visiting Cardiologist Breach Candy Hospital, Jaslok Hospital and HN Reliance Hospital Mumbai, Maharashtra, India Edited by MILIND Y NADKAR MD FICP FACP Professor of Medicine & Chief of Rheumatology & Emergency Medicine Seth GS Medical College and KEM Hospital Mumbai, Maharashtra, India The Health Sciences Publisher New Delhi | London | Panama mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com Jaypee Brothers Medical Publishers (P) Ltd Headquarters Jaypee Brothers Medical Publishers (P) Ltd. 4838/24, Ansari Road, Daryaganj New Delhi 110 002, India Phone: +91-11-43574357 Fax: +91-11-43574314 E-mail: Preface The purpose and scope of this widely read book at times referred to as a Bible in Medicine remains the same when it was frst published in the year 1952 namely to help the undergraduate medical students with necessary information presented on easily imbibable form for the fnal MBBS examination both for Theory and Viva. Over the years, the book has spread its wings. To add to this its aim is the acceptance by the students of Homeopathy, Dentistry, Physiotherapy and even Ayurveda, where the question papers in the subject of Medicine have found wide approval. The original author of the book has been aging but the younger author is aware that new vigour and fresh ideas are needed to ensure that every aspect in the test is kept up-to-date. The authors welcome the Editor, a pupil of the senior author in yesteryears and now a distinguished head of the leading monthly journal in the country and other literary achievements as a collaborator in this revised edition, and also for such future revisions that will be called for. Illustrations have been used freely whenever it was thought they would be purposeful in pathogenesis and diagnosis of diseases. There are more number of tables and fgures introduced in this edition. There might be room for improvement in some aspects, notwithstanding the amount of time and labour bestowed upon it. Criticisms and suggestions are invited and will be received with gratitude by the authors and Editor. Date of Publication December 2016 Aspi F Golwalla Sharukh A Golwalla Edited by Milind Y Nadkar mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com contents 1. Gastroenterology .............................................................................................................................................1 Investigations of gastrointestinal disease 1 The tongue in diagnosis 4 Stomatitis and oral ulceration 7 Dysphagia 7 Gastro-oesophageal refux disease 11 Achalasia of the cardia 12 Hiatal hernia 14 Dyspepsia 14 H. pylori infections 15 Gastritis 17 Peptic ulcer 17 Gastric cancer 23 Hematemesis and melaena 24 Lower gastrointestinal haemorrhage 27 Diarrhoea 29 Constipation 32 Malabsorption 33 Coeliac disease 36 Abdominal tuberculosis 38 Irritable bowel syndrome 39 Diverticular disease 41 Infammatory bowel disease 42 Ischemic bowel disease 47 Drug-induced gastrointestinal disorders 48 Factitious gastrointestinal symptoms and Munchausen 49 2. Hepatobiliary and Pancreatic Disease .......................................................................................................51 Investigating and imaging the liver, biliary tract and pancreas 51 Viral hepatitis 55 Autoimmune liver disease 61 Metabolic liver disease 64 Hepatic encephalopathy 67 Acute liver failure 69 Jaundice 71 Cirrhosis of liver 78 Ascites 84 Portal hypertension 90 Hepatomegaly 92 Liver disease in pregnancy 95 Drug-induced liver disease 95 mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com viii Medicine for Students Liver transplantation 95 Gallstones 97 Pancreatic disease 99 3. The Respiratory System ..............................................................................................................................103 Investigations of respiratory disease 103 Cough and expectoration 110 Haemoptysis 112 Infammation of the bronchial tree 114 Bronchial asthma 119 Chronic obstructive pulmonary disease (COPD) 124 Cystic fbrosis 129 Pneumonia 130 Lung abscess 136 Pulmonary tuberculosis 139 Pulmonary eosinophilia 147 Lung cancer 150 Pulmonary oedema 154 Pulmonary thromboembolism 155 Fungal infections of the lung 157 Airway problems in children 160 Pulmonary sarcoidosis 161 Diffuse parenchymal lung disease 162 Occupational lung disease 166 Lobar collapse of the lung 168 Sleep apnoea syndrome 169 Respiratory failure 171 Acute lung injury and acute respiratory distress syndrome 173 Severe acute respiratory syndrome (SARS) 175 Systemic diseases and the lungs 176 Pleural disease 178 Therapeutic aerosols 192 Drugs and the lungs 193 Respiratory problems in immunosuppressed patients 193 Lung transplantation 193 Miscellaneous 195 4. The Cardiovascular System ........................................................................................................................196 Investigations in cardiovascular diseases 196 Pulse 204 Cardiac arrhythmias 207 Cardiac murmurs 230 Congenital heart disease 233 Valvular heart disease 249 Infective endocarditis 265 Cardiovascular syphilis 270 Ischaemic heart disease 271 Cardiac arrest 289 mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com Contents ix Heart failure 291 Shock 296 Hypertension 298 Heart muscle disease 307 Neurocirculatory asthenia 312 Pericardial disease 313 Pulmonary hypertension 319 Heart disease and pregnancy 321 Paroxysmal dyspnoea 322 Diseases of vessels 324 5. Haematology ................................................................................................................................................335 Laboratory diagnosis in haematology 335 Haematopoiesis 342 Anaemias 345 Bone marrow failure 363 Amegakaryocytic thrombocytopenia 366 Porphyrias 366 Disorders of haemostasis 366 Anticoagulant drugs 376 Myelodysplastic syndromes 378 Leukemias 382 Lymphomas 391 Blood transfusion 400 Antiplatelet drug therapy 402 The spleen 403 Bone marrow transplantation 409 The blood in systemic disease 410 6. Endocrine Disorders ....................................................................................................................................412 Pituitary gland 412 Obesity 421 Thyroid disease 424 Thyroid goiter 433 Parathyroid disorders 435 The adrenals 439 Pancreas 445 Hypoglycaemia 466 Multiple endocrine neoplasia men 468 Carcinoid syndrome 468 Miscellaneous 470 7. Neurology .....................................................................................................................................................471 Investigations in neurology 471 Disorders of speech 480 The cranial nerves 483 Pupillary disorders 491 mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com x Medicine for Students Sensory impairment 493 The refexes 494 Neurological disturbances of bladder and bowel 495 Involuntary movements 497 Gaits 501 Headache 503 Epilepsy 507 Cerebrovascular diseases 514 Coma and brainstem death 530 Neurosyphilis 537 Tuberculosis of the central nervous system 539 Intracranial tumours 542 Disorders of the spinal cord 546 Defciency disorders of the nervous system 561 Extrapyramidal syndromes 562 Hereditary and degenerative disorders 567 Cerebellum and its disorders 571 Myopathies 574 Myasthenia gravis 580 Muscular wasting 583 Peripheral neuropathy 584 Root and plexus syndromes 592 8. Renal Disorders ...........................................................................................................................................597 Investigations in renal disease 597 Hematuria 606 Glomerular diseases 608 Acute renal failure (ARF) 615 Chronic kidney disease (CKD) 619 Urinary tract infection (UTI) 627 Polycystic disease of kidneys 630 Tubulo-interstitial disorders 631 Urinary calculi 633 Incontinence of urine 634 Kidney in systemic disease 636 Adverse effects of drugs on the kidney 637 Renal disease and pregnancy 637 Urinary catheterization 639 Stem cell therapy for kidney disease 641 9. Rheumatology ..............................................................................................................................................642 Investigations 642 Rheumatoid arthritis 645 Spondyloarthropathies 653 Joint and bone infections 660 Osteoarthritis 662 mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com Contents xi Metabolic and crystal athropathies 664 Autoimmune diseases 669 Vasculitides 680 Bone disorders 686 Miscellaneous 691 1 0. Infectious Diseases and Infections ............................................................................................................693 Diphtheria 693 Meningitis 695 Viral infections 698 Acute childhood exanthemas 708 Mumps 714 Whooping cough (pertussis) 715 Enterovirus infections 716 Toxoplasmosis 720 Tetanus and other clostridial diseases 720 Lyme disease 724 Legionnaires’ disease 724 11. Tropical Diseases .........................................................................................................................................727 Protozoal infections 727 Protozoal GI infections 736 Gastroenteritis 741 Plague 746 Brucellosis 747 Leprosy 749 Rickettsial diseases 752 Rabies 753 Dengue 755 Chikungunya 757 Hantavirus infection 758 Japanese B encephalitis 758 Rat-bite fever 759 Leptospirosis 759 Anthrax 760 Filarial infections 761 Tropical polymyositis 763 Intestinal helminths 763 Schistosomiasis (bilhariziasis) 768 Hydatid disease 770 Dracunculiasis (guinea-worm disease) 772 Tropical sprue 773 Effects of heat 774 Endemic fuorosis 775 1 2. Diseases of Children ...................................................................................................................................777 Newborn infants 777 Diseases of the newborn 780 mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com mebooksfree.com
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