Nages Nagaratnam Kujan Nagaratnam Gary Cheuk Geriatric Diseases Evaluation and Management Geriatric Diseases (cid:129) Nages Nagaratnam Kujan Nagaratnam Gary Cheuk Geriatric Diseases Evaluation and Management With90Figuresand79Tables NagesNagaratnam KujanNagaratnam TheUniversityofSydney TheUniversityofSydney WestmeadClinicalSchool WestmeadClinicalSchool Westmead,NSW,Australia Westmead,NSW,Australia GaryCheuk RehabilitationandAgedCareService Blacktown-MtDruittHospital MountDruitt,NSW,Australia ISBN978-3-319-33433-2 ISBN978-3-319-33434-9(eBook) ISBN978-3-319-33435-6(printandelectronicbundle) https://doi.org/10.1007/978-3-319-33434-9 LibraryofCongressControlNumber:2017964114 #SpringerInternationalPublishingAG,partofSpringerNature2018 Thisworkissubjecttocopyright.AllrightsarereservedbythePublisher,whetherthewholeor part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations,recitation,broadcasting,reproductiononmicrofilmsorinanyotherphysicalway, andtransmissionorinformationstorageandretrieval,electronicadaptation,computersoftware,or bysimilarordissimilarmethodologynowknownorhereafterdeveloped. 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Printedonacid-freepaper ThisSpringerimprintispublishedbytheregisteredcompanySpringerInternationalPublishing AGpartofSpringerNature Theregisteredcompanyaddressis:Gewerbestrasse11,6330Cham,Switzerland To our wives Rajarajeswari, Gowrie and Danielle Preface Many developed countries have experienced ageing demographics since the early 1900s, especially in the oldest old, the ones over 85. This trend of increased longevity showed little signs of abatement thus far, but with the increasedprevalenceoflifestylediseasessuchasobesity,typeIIdiabetesand hypertension,somehadpredictedthatitwillslowormayevenreverse. Ageing is associated with a multitude of physiological changes and a prevalence of multiple co-morbidities. This often leads to atypical presenta- tionsofcommondiseases.Forexample,itiscommonforaninfectiveillnessto presentwithfalls,cognitiveorfunctionaldecline.Itisalsoknownthattheage ofonsetcanleadtodifferentdiseasepresentationasinthecaseoflate-onset Parkinson’s disease, where the typical resting tremor is often absent. It is therefore important for clinicians managing older persons to have an acute awarenessofthe way that age-related physiological changes and co-existing co-morbiditiescaninfluencethewayanolderpersonpresents. Geriatric Medicine: Evaluation and Management provides a comprehen- siveoverviewoftheimportanceofageofonsetonthepresentationofcommon diseasesin the elderly. Apart from providing intense information on a given subject, it also provides means for self-assessment with a combination of multiple choice, short answer and extended matching questions which are basedonthetext.Interestingshortcasesarealsoincluded.Theextensiveuse oftablesandfiguresthroughoutthebookandaboxforkeypointsattheendof eachpartshouldbeagreatassistancetotime-poorreaders. Thebookcontains21partsarrangedbyorgansystemandisstructuredto coverthespecificclinicalsub-specialitieswithemphasisontheageatonset. Theyaredividedintointroduction,clinicalexpressionfollowedbydiagnosis and treatment. Many parts follow a common pattern with headings and sub- headings.Thetextofferstheprimarycarephysicians,juniordoctors,medical undergraduates, specialist nurses and others working in aged-care settings a systematic approach to geriatric medicine. The book we believe will be a companion to theone publishedearlier, by thesame authors Diseases inthe Elderly:Age-RelatedChangesandPathophysiology. NagesNagaratnam KujanNagaratnam GaryCheuk vii Acknowledgements WethankMr.LukeElias(PhysicalMedicine),Dr.DuncanGuy(Cardiology), Dr. Logan Kanagaratnam (Cardiology), Prof. Arumugam Manoharan (Haematology), Prof. Mahendra Somasunderam (Neurology), Dr. J. Sarks (Ophthalmology), Dr. A. PunniaMoorthy (Oral and Maxillofacial) for their helpinmanyways.AspecialthankstoAssoc.Prof.WMAmoaku(University of Nottingham), Dr. Derek Davies (Dermatology), Prof. Nicholas Manolios (The University of Sydney), Dr. Thiaga Nadaraja (ENT) and Dr.P.Nithianandan(Ophthalmology)forkindlyprovidingnumerousfigures, and Mr. Yogan Nagaratnam, Mr. Panjan Nagaratnam (for photographs), Sai AditiyaNagaratnam,NathanNagaratnamandManishaNagaratnamfortheir assistance. ix Disclaimer Continuous development and research in the fields of medicine, science technologyandhealthcareresultinongoingchangesinthedomainsofclinical practice as evidence continues to evolve rapidly. We have taken reasonable careandefforttoprovidematerialswhicharecurrent,accurateandbalancedat thetimeofpublication. Weandthepublishersdonotacceptresponsibilityorliabilityforanyerrors inthetextoranyconsequencesarisingfromtheinformation,forinstance,to takethedrugdosagesascorrect.Theinformationprovidedisneutralandfor general education and does not replace interaction with the practicing clini- cian.Cliniciansshoulddependontheirownexperiencewhenprovidingadvice ortreatment. We have acknowledged the sources and works of the cited sites at the appropriate locations in the text and references. We have used the source materials in the sense of fair use and extend our apology for any oversight. Readersareadvisedtocross-referenceandconfirmpointsrelevanttothem. xi Contents PartI CardiovascularDiseasesintheElderly ................ 1 1 HeartFailure ...................................... 3 2 CardiacArrhythmias ............................... 17 3 InfectiveEndocarditis ............................... 29 4 CoronaryArteryDisease ............................. 37 5 ValvularHeartDiseaseintheElderly .................. 47 6 HypertensionintheElderly .......................... 57 7 PeripheralArterialDisease ........................... 67 PartII RespiratoryDiseasesintheElderly ................... 75 8 PneumoniainGeriatricPatients ....................... 77 9 ChronicObstructivePulmonaryDisease(COPD) ......... 89 10 AsthmaintheElderly ............................... 99 11 LungCancerintheElderly ........................... 105 12 PulmonaryEmbolism ............................... 113 13 SleepDisorders .................................... 121 PartIII DisordersoftheDigestiveTractintheElderly ....... 125 14 TheOesophagusandOesophagealDisorders ............ 127 15 PepticUlcerDiseaseintheElderly ..................... 143 16 ColorectalCancer .................................. 147 17 InflammatoryBowelDiseaseintheElderly .............. 153 18 GastrointestinalBleedingintheElderly ................ 161 xiii xiv Contents 19 AcuteAbdominalPainintheElderly ................... 169 20 InfectiousDiarrhoeasintheElderly .................... 179 PartIV LiverDiseasesintheElderly ........................ 187 21 ViralHepatitisintheElderly ......................... 189 22 ChronicLiverDisease ............................... 203 23 HepatocellularCarcinoma ........................... 217 24 AscitesintheElderly ................................ 221 PartV BloodDisordersintheElderly ....................... 227 25 TheAnaemias ..................................... 229 26 MyelodysplasticSyndromes .......................... 239 27 MyeloproliferativeNeoplasms ........................ 243 28 ImmunoproliferativeDisorders ....................... 253 29 LymphoproliferativeDisorders ........................ 259 PartVI RenalandLowerUrinaryTractDisordersin theElderly .................................................. 267 30 GlomerularDiseaseintheElderly ..................... 269 31 RenovascularDiseaseintheElderly .................... 273 32 AcuteKidneyInjury ................................ 277 33 ChronicKidneyDiseaseintheElderly .................. 287 34 ProstateGlandandRelatedDisorders .................. 297 35 MaleSexualDysfunction:ErectileDysfunction(ED) ...... 309 PartVII NeurologicalDisordersintheElderly ............... 315 36 Parkinson’sDisease ................................. 317 37 MultisystemAtrophy(MSA) .......................... 329 38 MotorNeuroneDisease .............................. 333 39 MultipleSclerosis ................................... 337 40 PeripheralNeuropathy .............................. 343 41 DisordersofNeuromuscularTransmission .............. 351 42 Epilepsy .......................................... 361