Downloaded from UvA-DARE, the institutional repository of the University of Amsterdam (UvA) http://hdl.handle.net/11245/2.94782 File ID uvapub:94782 Filename Thesis Version unknown SOURCE (OR PART OF THE FOLLOWING SOURCE): Type PhD thesis Title Screening, geriatric assessment and intervention strategies to prevent functional decline in hospitalized older patients Author(s) B.M. Buurman Faculty AMC-UvA Year 2011 FULL BIBLIOGRAPHIC DETAILS: http://hdl.handle.net/11245/1.366259 Copyright It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content licence (like Creative Commons). UvA-DARE is a service provided by the library of the University of Amsterdam (http://dare.uva.nl) (pagedate: 2014-11-22) S c r e e n in g , G Screening, Geriatric Assessment and e r ia t r Intervention Strategies to Prevent Functional ic A s s e s Decline in Hospitalized Older Patients s m Uitnodiging e n t a voor het bijwonen van de n d openbare verdediging van In t het proefschrift e r v e n t "Screening, Geriatric io n Assessment and S tr Intervention Strategies to a t e Prevent Functional Decline g ie in Hospitalized Older s t o Patients" P r e v e door n t F Bianca M. Buurman u n c t io Op vrijdag 16 september n a 2011, om 11:00 l D e Aula van de Universiteit, c lin Singel 411, Amsterdam e in H Receptie ter plaatse na o s p afloop van de promotie it a liz e Bianca M. Buurman d O Marsstraat 61 ld e 2024 GB Haarlem r P a [email protected] t ie n t s Paranimfen: B Bianca M. Buurman Marike van der Leeden ia [email protected] n c a 06-55848662 M . B & u Jacqueline Suijker u r m [email protected] a n 06-24218690 Screening, Geriatric Assessment and Intervention Strategies to Prevent Functional Decline in Hospitalized Older Patients Screening, Geriatric Assessment and Intervention Strategies to Prevent Functional Decline in Hospitalized Older Patients. PhD thesis, University of Amsterdam, The Netherlands © Bianca M. Buurman, Haarlem, The Netherlands 2011 All rights reserved. No part of this thesis may be reproduced or transmitted in any form or by any means without prior permission of the author. A digital version of this thesis can be found at www.dare.uva.nl Lay‐out & Cover: J.W. Broek Printed by: Gildeprint (www.gildeprint.nl) The printing of this thesis is financially supported by: Nutricia Advanced Medical Nutrition, Novartis Pharma B.V., Lundbeck B.V. Screening, Geriatric Assessment and Intervention Strategies to Prevent Functional Decline in Hospitalized Older Patients ACADEMISCH PROEFSCHRIFT ter verkrijging van de graad van doctor aan de Universiteit van Amsterdam op gezag van de Rector Magnificus prof. dr. D.C. van den Boom ten overstaan van een door het college voor promoties ingestelde commissie, in het openbaar te verdedigen in de Aula der Universiteit op vrijdag 16 september 2011, te 11.00 uur door Bianca Maria Van Es geboren te Rotterdam Promotiecommissie Promotores: Prof. dr. M.M. Levi Prof. dr. R.J. de Haan Co‐promotor Dr. S.E.J.A. de Rooij Overige leden: Prof. dr. P.J.M. Bakker Prof. dr. J. Gussekloo Prof. dr. M.G.M Olde‐Rikkert Prof. dr. E. Schadé Prof. dr. I.N. van Schaik Faculteit der Geneeskunde Contents Chapter 1 General Introduction 7 Chapter 2 Variability in Measuring (I)ADL Functioning and Functional Decline in Hospitalized Older Medical Patients: a Systematic Review 19 Chapter 3 Risk for Poor Outcomes in Older Patients Discharged from an Emergency Department: Feasibility of Four Screening Instruments 39 Chapter 4 Prognostication in Acutely Admitted Older Patients by Nurses and Physicians 55 Chapter 5 The Prediction of Functional Decline in Older Hospitalized Patients 77 Chapter 6 Geriatric Conditions in Acutely Hospitalized Older Patients: Prevalence and One‐year Survival, Functional Decline and Cognitive Impairment 95 Chapter 7 Clinical Characteristics and Outcomes of Hospitalized Older Patients with Distinct Risk Profiles for Functional Decline: a Prospective Cohort Study 115 Chapter 8 A Randomised Clinical Trial on Comprehensive Geriatric Assessment and Intensive Home Follow‐up after Hospital Discharge: the Transitional Care Bridge 135 Chapter 9 General Discussion 155 Chapter 10 Summary 169 Chapter 11 Summary in Dutch (Samenvatting) 175 Publications 181 Curriculum Vitae 187 Acknowledgements (Dankwoord) 189 General Introduction Chapter 1 Excerpt of the introduction and general discussion submitted for publication ‘Acute hospitalization and disability’ Chapter 1 Chronic diseases and the onset of disability The prevalence of chronic diseases gradually increases with age and has shown an overall growth in the past decades 1. This is partly due to early recognition of chronic diseases by screening programs and to aging of the population. Compared to patients younger than 65 years, older patients more frequently have a combination of chronic diseases. This co‐ occurrence of two or more diseases is defined as multimorbidity 2 and its prevalence in community‐dwelling patients ranges from 35‐65% in patients aged 60‐69 years, to 80‐99% in patients aged 80 years and older 3;4. Chronic diseases are often accompanied by disability. In order to structure and describe disease outcomes in a systematic and hierarchical manner the World health Organization developed the International Classification of Functioning, Disability and Health (ICF, Figure 1) 5 6. According to this scheme the disablement process starts with a certain disease or health condition in the body. The specific disease can lead to impairments in body functions and structures, such as retinopathy (impairment) in diabetes patients (underlying disease). Impairments can be clinically silent or can be detectable and may lead to functional limitations (disabilities) which in turn may result in societal disadvantages (restrictions in participation or handicap). Important components of the ICF are the environmental and personal factors of the patients that can speed up or slow down the disablement process. Environmental factors concern the presence of primary care givers, social support, technological devices and financial resources which can compensate a persons’ individual inability to perform certain activities. Personal factors such as personality traits, coping styles, educational level, and lifestyle are far more difficult to influence. 8
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