1600 John F. Kennedy Blvd. Ste 1800 Philadelphia, PA 19103-2899 GERIATRIC CLINICAL ADVISOR: INSTANT DIAGNOSIS AND TREATMENT ISBN-13: 978-0-323-04195-9 ISBN-10: 0-323-04195-7 Copyright © 2007 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Permissions may be sought directly from Elsevier's Health Sciences Rights Department in Philadelphia, PA, USA: phone: (+1) 215 239 3804, fax: (+1) 215 239 3805, e-mail: [email protected]. You may also complete your request on-line via the Elsevier homepage (http://www.elsevier.com), by selecting “Customer Support” and then “Obtaining Permissions.” Notice Knowledge and best practice in this field are constantly changing. As new research and experience broaden our knowledge, changes in practice, treatment, and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of the practitioner, relying on his or her own experience and knowledge of the patient, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the Editor assumes any liability for any injury and/or damage to persons or property arising out of or related to any use of the material contained in this book. The Publisher International Standard Book Number 0-323-04195-7 International Standard Book Number (PDA online) 0-323-04356-9 Acquisitions Editor:Rolla Couchman Developmental Editor:Mary Beth Murphy Printed in the United States of America Last digit is the print number: 9 8 7 6 5 4 3 2 1 The editors would like to dedicate this book to their families and friends. FM-A04195_i-xviii.qxd 6/16/06 12:39 PM Page v Associate Editors FRED F. FERRI, M.D., F.A.C.P. JOHN B. MURPHY, M.D. Clinical Professor Division of Geriatrics Department of Community Health Rhode Island Hospital Brown Medical School Providence, Rhode Island Providence, Rhode Island APPENDIX 1: SYSTEMS OF GERIATRIC CARE SECTION I: DISEASES AND DISORDERS, AMAN NANDA, M.D., C.M.D. SECTION II: DIFFERENTIAL DIAGNOSIS, SECTION III: CLINICAL ALGORITHMS, Assistant Professor in Medicine SECTION IV: LABORATORY TESTS AND INTERPRETATION Brown Medical School OF RESULTS Providence, Rhode Island APPENDIX 2: TOOLS OF GERIATRIC ASSESSMENT CYNTHIA HOLZER, M.D, C.M.D. Director, Geriatric Education TOM J. WACHTEL, M.D., F.A.C.P. Roger Williams Medical Center Division of Geriatrics Providence, Rhode Island Rhode Island Hospital Assistant Professor of Medicine Professor of Community Health and Medicine Boston University School of Medicine Brown Medical School Boston, Massachusetts Providence, Rhode Island SECTION V: CLINICAL PREVENTIVE SERVICES SECTION I: DISEASES AND DISORDERS, SECTION II: DIFFERENTIAL DIAGNOSIS, LYNN MCNICOLL, M.D. SECTION III: CLINICAL ALGORITHMS, Division of Geriatrics SECTION IV: LABORATORY TESTS AND INTERPRETATION Rhode Island Hospital OF RESULTS, Providence, Rhode Island APPENDIX 1: SYSTEMS OF GERIATRIC CARE SECTION I: DISEASES AND DISORDERS v FM-A04195_i-xviii.qxd 6/16/06 12:39 PM Page vi Contributors PHILIP J. ALIOTTA, M.D., M.S.H.A., F.A.C.S. JOHN E. CROOM, M.D., PH.D. Clinical Instructor Clinical Fellow in Neurology Department of Urology Harvard Medical School School of Medicine and Biomedical Sciences Beth Israel Deaconess Medical Center State University of New York at Buffalo Boston, Massachusetts Buffalo, New York Medical Director CLAUDIA L. DADE, M.D. Center for Urologic Research of Western New York Attending Physician Williamsville, New York Division of Infectious Diseases GEORGE O. ALONSO, M.D. Elmhurst Hospital Center Elmhurst, New York Director Instructor in Medicine Department of Infection Control Mount Sinai School of Medicine Elmhurst Hospital Center New York, New York Elmhurst, New York Instructor in Medicine Mount Sinai School of Medicine GEORGE T. DANAKAS, M.D., F.A.C.O.G. New York, New York Clinical Assistant Professor Department of Obstetrics and Gynecology MEL L. ANDERSON, M.D., F.A.C.P. State University of New York at Buffalo Clinical Assistant Professor of Medicine Buffalo, New York Brown Medical School Providence, Rhode Island AMAR DESAI, M.D., M.P.H. PATRICIA AREAN, PH.D. Resident Physician Associate Professor Department of Internal Medicine Department of Psychiatry University of California, San Francisco University of California, San Francisco San Francisco, California San Francisco, California MICHAEL G. BENATAR, M.B.CH.B., D.PHIL. JEFFREY S. DURMER, M.D., PH.D. Assistant Professor of Neurology Assistant Professor, Department of Neurology Department of Neurology Director, Emory Sleep Laboratory Emory University Director, Egleston Children’s Hospital Sleep Clinic Atlanta, Georgia Emory University School of Medicine Atlanta, Georgia SUSAN BERNER, M.D. Geriatrics Fellow, Department of Family Medicine GARY EPSTEIN-LUBOW, M.D. University of Cincinnati College of Medicine Postdoctoral Research Fellow Cincinnati, Ohio Department of Psychiatry and Human Behavior Brown Medical School LYNN BOWLBY, M.D. Staff Psychiatrist Attending Physician Butler Hospital Division of General Internal Medicine Providence, Rhode Island Rhode Island Hospital Clinical Instructor of Medicine Brown Medical School MARK J. FAGAN, M.D. Providence, Rhode Island Director Medical Primary Care Unit MARIA A. CORIGLIANO, M.D., F.A.C.O.G. Rhode Island Hospital Clinical Assistant Professor Associate Professor of Medicine Department of Obstetrics and Gynecology Brown Medical School State University of New York at Buffalo Providence, Rhode Island Buffalo, New York STEPHEN CORREIA, PH.D. GIL M. FARKASH, M.D. Dementia Research Fellow Assistant Clinical Professor Department of Psychiatry and Human Behavior State University of New York at Buffalo Brown Medical School School of Medicine Providence, Rhode Island Buffalo, New York vi FM-A04195_i-xviii.qxd 6/16/06 12:39 PM Page vii Contributors vii MITCHELL D. FELDMAN, M.D., M.PHIL. CYNTHIA HOLZER, M.D., C.M.D. Associate Professor of Clinical Medicine Director, Geriatric Education University of California, San Francisco Roger Williams Medical Center Division of General Internal Medicine Providence, Rhode Island San Francisco, California Assistant Professor of Medicine Boston University School of Medicine FRED F. FERRI, M.D., F.A.C.P. Boston, Massachusetts Clinical Professor Department of Community Health JASON IANNUCCILLI, M.D. Brown Medical School Department of Medicine Providence, Rhode Island Brown Medical School Providence, Rhode Island GLENN G. FORT, M.D., M.P.H. RICHARD S. ISAACSON, M.D. Clinical Associate Professor of Medicine Brown Medical School Director, Research Unit in Medical Education Chief Associate Medical Director Infectious Diseases Wien Center for Memory Disorders and Alzheimer’s Disease Our Lady of Fatima Hospital Assistant Professor of Medicine North Providence, Rhode Island University of Miami—Leonard M. Miller School of Medicine Departments of Medical Education, Internal Medicine, and MICHAEL P. GERARDO, D.O., M.P.H. Neurology Post-Doctoral Research Fellow Mount Sinai Medical Center Brown Medical School, Center for Gerontology and Health Miami Beach, Florida Care Research BREE JOHNSTON, M.D., M.P.H. Brown University Geriatric Medicine Fellow Associate Professor of Medicine Rhode Island and Miriam Hospitals Division of Geriatrics Providence, Rhode Island Department of Medicine Veterans Affairs Medical Center SUSAN E. HARDY, M.D., PH.D. University of California, San Diego Assistant Professor San Diego, California Geriatric Medicine University of Pittsburgh School of Medicine MELVYN KOBY, M.D. Pittsburgh, Pennsylvania Associate Clinical Professor of Medicine Department of Ophthalmology MIKE HARPER, M.D. University of Louisville School of Medicine Associate Professor of Medicine Louisville, Kentucky Division of Geriatrics Department of Medicine E. GORDON MARGOLIN, M.D. San Francisco Veterans Affairs Medical Center Professor, Internal Medicine and Geriatrician University of California, San Diego University of Cincinnati College of Medicine San Diego, California Cincinnati, Ohio TAYLOR HARRISON, M.D. DANIEL T. MATTSON, M.D., M.S.C.(MED.) Neuromuscular Fellow Clinical Fellow in Neurology Department of Neurology Beth Israel Deaconess Medical Center Emory University Harvard Medical School Atlanta, Georgia Boston, Massachusetts SHARON S. HARTMAN, M.D., PH.D. LYNN MCNICOLL, M.D. Clinical Associate Division of Geriatrics Department of Neurology Rhode Island Hospital Emory University Providence, Rhode Island Atlanta, Georgia LONNIE R. MERCIER, M.D. HOLLY M. HOLMES, M.D. Clinical Instructor Instructor Department of Orthopedic Surgery University of Chicago Creighton University School of Medicine Chicago, Illinois Omaha, Nebraska FM-A04195_i-xviii.qxd 6/16/06 12:39 PM Page viii Contributors viii DENNIS J. MIKOLICH, M.D., F.A.C.P., F.C.C.P. SEAN I. SAVITZ, M.D. Chief Clinical Fellow in Neurology Division of Infectious Diseases Harvard Medical School VA Medical Center Chief Resident in Neurology Clinical Associate Professor of Medicine Beth Israel Deaconess Medical Center Brown Medical School Boston, Massachusetts Providence, Rhode Island JOSEPH W. SHEGA, M.D. RAM R. MILLER, M.D.C.M., M.S., F.R.C.P.C. Assistant Professor, Division of Hematology/Oncology Northwestern University Assistant Professor The Feinberg School of Medicine University of Maryland School of Medicine Chicago, Illinois Division of Gerontology Department of Epidemiology and Preventive Medicine CLIFFORD MILO SINGER, M.D. Baltimore, Maryland Associate Professor of Psychiatry Director, Insomnia and Chronobiology Clinic ARVIND MODAWAL, M.D., M.P.H., M.R.C.G.P. Vermont Regional Sleep Center Associate Professor University of Vermont College of Medicine Department of Family Medicine, Section of Geriatrics Burlington, Vermont University of Cincinnati College of Medicine Cincinnati, Ohio U. SHIVRAJ SOHUR, M.D., PH.D. Clinical Fellow in Neurology JOHN B. MURPHY, M.D. Harvard Medical School Division of Geriatrics Chief Resident in Neurology Rhode Island Hospital Beth Israel Deaconess Medical Center Providence, Rhode Island Boston, Massachusetts JOHN A. STOUKIDES, M.D., R.PH. AMAN NANDA, M.D., C.M.D. Director of Geriatrics Assistant Professor in Medicine Roger Williams Medical Center Brown Medical School Providence, Rhode Island Providence, Rhode Island Clinical Assistant Professor of Medicine Boston University School of Medicine TAKUMA NEMOTO, M.D. Boston, Massachusetts Research Associate Professor of Surgery Adjunct Associate Professor of Pharmacy and Nursing State University of New York at Buffalo University of Rhode Island Buffalo, New York Kingston, Rhode Island PRANAV M. PATEL, M.D. JULIE ANNE SZUMIGALA, M.D. Clinical Associate Instructor, Division of Cardiology Clinical Instructor Department of Medicine Department of Obstetrics and Gynecology Brown Medical School State University of New York at Buffalo Providence, Rhode Island Buffalo, New York LAURA TRICE, M.D. PETER PETROPOULOS, M.D. Medical Director Department of Veterans Affairs Trihealth SeniorLink Providence, Rhode Island California, Kentucky ARUNDATHI G. PRASAD, M.D. EROBOGHENE E. UBOGU, M.D. Clinical Instructor Assistant Professor of Neurology Department of Obstetrics and Gynecology/Resident Education Case Western Reserve University School of Medicine State University of New York at Buffalo Staff Neurologist Women’s and Children’s Hospital Louis Stokes Cleveland Veterans Affairs Medical Center Buffalo, New York Cleveland, Ohio HARLAN G. RICH, M.D. TOM J. WACHTEL, M.D., F.A.C.P. Director of Endoscopy Division of Geriatrics Rhode Island Hospital Rhode Island Hospital Associate Professor of Medicine Professor of Community Health and Medicine Brown Medical School Brown Medical School Providence, Rhode Island Providence, Rhode Island FM-A04195_i-xviii.qxd 6/16/06 12:39 PM Page ix Contributors ix WEN-CHIH WU, M.D. MADHAVI YERNENI, M.D. Assistant Professor of Medicine Staff Physician, Academic Medical Center Brown Medical School Miriam Hospital Cardiologist Pawtucket, Rhode Island Providence VA Medical Center Providence, Rhode Island CINDY ZADIKOFF, M.D. BETH J. WUTZ, M.D. Fellow, Movement Disorders Clinical Assistant Professor of Medicine Morton and Gloria Shulman Movement Disorders Center Division of Internal Medicine/Pediatrics Toronto Western Hospital Kajeida Health–Buffalo General Hospital Toronto, Ontario State University of New York at Buffalo Buffalo, New York
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