SEVENTH EDITION L A N G E Q & A™ P E D I AT R I C S Mary Anne Jackson, MD Chief, Section of Pediatric Infectious Diseases Children’s Mercy Hospital & Clinics Professor of Pediatrics University of Missouri, Kansas City School of Medicine Kansas City, Missouri Sara S. Viessman, MD Former Director, Pediatric Residency Program and Associate Professor Former Director, Med-Peds Residency Program University of Missouri-Columbia School of Medicine Columbia, Missouri Former Associate Dean for Medical Education at Lehigh Valley Hospital Penn State College of Medicine Allentown, Pennsylvania New York Chicago San Francisco Lisbon London Madrid Mexico City Milan New Delhi San Juan Seoul Singapore Sydney Toronto Copyright © 2010 by The McGraw-Hill Companies, Inc. All rights reserved. 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Contents Contributors ........................................................................................................................................................... v Student Reviewers.............................................................................................................................................. vii Preface .................................................................................................................................................................... ix Acknowledgements .............................................................................................................................................. x 1. Warm-Up Questions and Exam-Taking Skills ......................................................................................... 1 MARYANNEJACKSON, MD Questions .......................................................................................................................................................... 2 Answers and Explanations ............................................................................................................................ 7 2. General Pediatrics ........................................................................................................................................ 15 CATALINAKERSTEN, MD Questions......................................................................................................................................................... 16 Answers and Explanations........................................................................................................................... 29 3. The Neonate .................................................................................................................................................. 49 EUGENIAK. PALLOTTO, MD Questions......................................................................................................................................................... 48 Answers and Explanations........................................................................................................................... 64 4. Growth and Development .......................................................................................................................... 81 SARAHE. HAMPL, MD Questions......................................................................................................................................................... 82 Answers and Explanations........................................................................................................................... 96 5. Feeding and Nutrition .............................................................................................................................. 109 SARAVIESSMAN, MD, MARYSTAHLLEVICK, MD, ANDWILLIAMJ KLISH, MD Questions........................................................................................................................................................ 110 Answers and Explanations.......................................................................................................................... 117 6. Fluids, Electrolytes, and Metabolic Disorders...................................................................................... 125 JOSEPHT. CERNICH, MD ANDANGELAL. TURPIN, MD Questions....................................................................................................................................................... 126 Answers and Explanations......................................................................................................................... 135 iii iv Contents 7. Infectious Diseases .................................................................................................................................... 147 EMILYA. THORELL, MD ANDANGELAMYERS, MD, MPH Questions....................................................................................................................................................... 148 Answers and Explanations......................................................................................................................... 164 8. Injuries, Poisoning, and Substance Abuse............................................................................................ 181 GARYS. WASSERMAN, DO, JENNIFERA. LOWRY, MD, ANDRICHARDJ. MAZZACCARO, PHD, MD Questions....................................................................................................................................................... 182 Answers and Explanations......................................................................................................................... 189 9. Pediatric Therapeutics .............................................................................................................................. 197 JASONW. CUSTER, MD, KRISTINEA. RAPAN, PHARMD,ANDR. BLAINEEASLEY, MD Questions....................................................................................................................................................... 198 Answers and Explanations......................................................................................................................... 213 10. Case Diagnosis and Management .......................................................................................................... 231 MARKA. WARD, MD ANDJOSEPHY. ALLEN, MD Questions....................................................................................................................................................... 232 Answers and Explanations......................................................................................................................... 252 11. Practice Test ................................................................................................................................................. 275 MARYANNEJACKSON, MD ANDSARAS. VIESSMAN, MD Questions....................................................................................................................................................... 276 Answers and Explanations......................................................................................................................... 296 Bibliography ...................................................................................................................................................... 315 Index..................................................................................................................................................................... 319 Contributors Joseph Y. Allen, MD, FAAP William J. Klish, MD Assistant Professor of Pediatrics Professor of Pediatrics Baylor College of Medicine Baylor College of Medicine Texas Children’s Hospital Texas Children’s Hospital Houston, Texas Houston, Texas Joseph T. Cernich, MD Mary Stahl-Levick, MD, FAAP Assistant Professor of Pediatrics Practicing General Pediatrician Section of Pediatric Endocrinology and Diabetes ABC Family Pediatricians Children’s Mercy Hospitals & Clinics Lehigh Valley Hospital and Health Network University of Missouri––Kansas City School Allentown, Pennsylvania of Medicine Kansas City, Missouri Jennifer A. Lowry, MD Assistant Professor Jason W. Custer, MD Division of Clinical Pharmacology and Medical Fellow Toxicology Department of Pediatric Critical Care University of Missouri––Kansas City School Johns Hopkins University of Medicine Baltimore, Maryland Children’s Mercy Hospitals & Clinics Kansas City, Missouri R. Blaine Easley, MD Assistant Professor Richard J. Mazzacarro, PhD, MD Department of Pediatrics, Anesthesiology Pediatric Hospitalist and Critical Care Department of Pediatrics Johns Hopkins Medical Institutes Lehigh Valley Hospital Baltimore, Maryland Allentown, Pennsylvania Sarah E. Hampl, MD Angela L. Myers, MD, MPH Assistant Professor of Pediatrics Associate Director, Infectious Diseases Children’s Mercy Hospitals & Clinics Fellowship Program University of Missouri––Kansas City School Assistant Professor of Pediatrics of Medicine University of Missouri––Kansas City School Kansas City, Missouri of Medicine Children’s Mercy Hospitals & Clinics Catalina M. Kersten, MD Kansas City, Missouri Assistant Clinical Professor Department of Child Health University of Missouri School of Medicine Columbia, Missouri v vi Contributors Eugenia K. Pallotto, MD Angela L. Turpin, MD Associate Medical Director Associate Medical Director of Diabetes Program Neonatal Intensive Care Unit Assistant Professor of Pediatrics Children's Mercy Hospital & Clinics University of Missouri––Kansas City School Assistant Professor of Pediatrics of Medicine University of Missouri––Kansas City School Children’s Mercy Hospitals & Clinics of Medicine Kansas City, Missouri Kansas City, Missouri Gary S. Wasserman, DO Kristine A. Parbuoni, PharmD, BCPS Chief, Section of Medical Toxicology Pediatric Clinical Pharmacy Specialist Professor of Pediatrics University of Maryland Medical Center University of Missouri––Kansas City Clinical Assistant Professor Children’s Mercy Hospitals & Clinics University of Maryland School of Pharmacy Kansas City, Missouri Baltimore, Maryland Emily Thorell, MD Visiting Instructor Department of Pediatric Infectious Disease University of Utah School of Medicine Salt Lake City, Utah Student Reviewers Joseph A. Bart Joshua Lynch, DO Lake Erie College of Osteopathic Medicine Resident, Emergency Medicine Class of 2009 University at Buffalo Steven Cohen Lisa A. Nowell, MD University of Missouri, Kansas City School of Medicine Resident, Morgan Stanley Children’s Hospital Class of 2009 New York Presbyterian, Columbia University Rose Ann Cyriac Crick Watkins University of Missouri, Kansas City School of Medicine Kansas City University of Medicine and Biosciences Class of 2009 Class of 2009 vii Preface If you are reading this book, you are likely engaged in one of the most important responsibilities of your career—caring for a child. Pediatric practitioners fulfill a unique role in medicine in that they see the patient across a continuum of time, often seeing the patient and their family for the first time in the first few minutes of life. As you look into the eyes of a parent and child, you recognize that the responsibility is beyond measure and the balance between providing comprehensive preventative health care and recognizing the need for more in-depth system-specific investigation or treatment can turn on a dime. It requires practitioners to have a solid knowledge base, be thorough in their assessments, be insightful regarding preventative care approaches, and, most importantly, be able to recognize when an urgent treatment plan is needed. This book should serve as an assessment tool for students, residents, and practitioners who wish to evalu- ate their pediatric knowledge base and clinical deductive skills. The question focus and organization of chap- ters were chosen to cover topics, by and large, consistent with the American Board of Pediatric general pediatric core competencies. Chapters cover a range of topics spanning ages from newborn, including the premature infant through adolescence. Comprehensive dedication to issues related to growth and development, feeding and nutrition, fluids, electrolytes, and metabolic disorders are included. The infectious disease chapter covers both common outpatient infection as well as life-threatening infections which occur in the healthy and immunocompromised host. The chapter on injuries, poisoning, and substance abuse provides review of clinical problems which may be seen on both outpatient and emergency care encounters. Critical care and pediatric therapeutic questions target distinctive clinical scenarios and require the clinician to make prompt, evidence- based medical decisions. The answers and discussion which follow each question include reference to key pediatric textbooks and American Academy of Pediatrics guidelines. To those who use this book, I hope you find it useful and that you are fueled throughout your career by the excitement of discovery stirred by your clinical experiences. Mary Anne Jackson, MD ix Acknowledgements Many thanks to Sara Viessman for trusting me to complete this labor of love, and to Dr. Martin Loren who first envisioned the text and brought the first five editions to fruition. It has been a pleasure to work with all of the authors that gave of their time and who represent expertise from pediatric centers across the United States. It has been my pleasure to work with Catherine Johnson, Cindy Yoo, and Kirsten Funk from McGraw-Hill. Their patience, advice, guidance, and encouragement have been invaluable. I would be remiss if I did not recognize my partners at work who daily remind me how lucky we are to do what we do. To Lindsay and Nick, seeing you challenge yourself throughout life, be it at work or play, has inspired me to broaden my own horizons. And to Jay, your unwavering love has energized me every day for 37 years. x
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