GeNeDis 2014: Geriatrics

135 Pages·2015·2.087 MB·English

by  Panayiotis Vlamos, Athanasios Alexiou (eds.)

Advances in Experimental Medicine and Biology 821
Panayiotis Vlamos
Athanasios Alexiou Editors
GeNeDis
2014
Geriatrics
Advances in Experimental Medicine and Biology
Volume 821
Editorial Board:
IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel
N.S.ABELLAJTHA,KlineInstituteforPsychiatricResearch,Orangeburg,NY,USA
RODOLFOPAOLETTI,UniversityofMilan,Milan,Italy
JOHND.LAMBRIS,UniversityofPennsylvania,Philadelphia,PA,USA
Moreinformationabout thisseries athttp://www.springer.com/series/5584

Panayiotis Vlamos (cid:129) Athanasios Alexiou
Editors
GeNeDis 2014
Geriatrics
Editors
PanayiotisVlamos AthanasiosAlexiou
DepartmentofInformatics DepartmentofInformatics
IonianUniversity IonianUniversity
Corfu,Greece Corfu,Greece
ISSN0065-2598 ISSN2214-8019(electronic)
ISBN978-3-319-08938-6 ISBN978-3-319-08939-3(eBook)
DOI10.1007/978-3-319-08939-3
SpringerChamHeidelbergNewYorkDordrechtLondon
LibraryofCongressControlNumber:2014954990
©SpringerInternationalPublishingSwitzerland2015
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Contents
1 Brain,BehaviourandEvolution. . . . . . . . . . . . . . . . . . . . . . . . . . . 1
GeorgePaxinos
2 SearchingforAD-RelatedBiologicalVulnerability
inCognitivelyIntactPeople:ANewPerspective
forMentalHealth. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
PanteleimonGiannakopoulos
3 ThePathfromObesityandHypertensiontoDementia. . . . . . . . . . 5
ArnoVillringer
4 ProteasomeActivationDelaysAgingandProtects
AgainstProteotoxicityinNeurodegenerativeDisease. . . . . . . . . . . 7
EfstathiosGonos
5 DecreaseinAmyloidDepositioninAging
Brain—AnAutopsyStudy. . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . 9
GabrielGold,Franc¸oisHerrmann,ConstantinBouras,
EnikoKo¨vari,andAikateriniXekardaki
6 NeuropathologicalChangesinAgingBrain. . . . . . . . . . . . . . . . . . 11
AikateriniXekardaki,EnikoKo¨vari,GabrielGold,
AdrianaPapadimitropoulou,EzioGiacobini,Franc¸oisHerrmann,
PanteleimonGiannakopoulos,andConstantinBouras
7 ArtificialHumanoidfortheElderlyPeople. . . . . . . . . . . . . . . . . . . 19
PanagiotaSimou,AthanasiosAlexiou,andKonstantinosTiligadis
8 DeprescribingPsychotropicMedicationsinAgedCare
Facilities:ThePotentialRoleofFamilyMembers. . . .. . . . . . .. . . 29
ChristosPlakiotis,J.SimonBell,Yun-HeeJeon,DimityPond,
andDanielW.O’Connor
v
vi Contents
9 FindingsRegardingtheRelationshipsBetween
Sociodemographic,Psychological,ComorbidityFactors,
andFunctionalStatus,inGeriatricInpatients. . . . . . . . . . . . . . . . 45
AnaCapisizu,SorinaAurelian,AndreeaZamfirescu,
IoanaOmer,MonicaHaras,CameliaCiobotaru,LilianaOnose,
TiberiuSpircu,andGeluOnose
10 TheRoleofChemicalEngineeringinMedicinalResearch
IncludingAlzheimer’s. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57
GeorgiosM.Kontogeorgis
11 OntheComparisonofaNovelSeriousGame
andElectroencephalographyBiomarkersforEarly
DementiaScreening. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63
IoannisTarnanas,NikosLaskaris,MagdaTsolaki,
Rene´ Muri,TobiasNef,andUrsP.Mosimann
12 OntheObservedSpecificandNon-specificEffects
ofComplexTherapeuticInterventions:TrulySeparate
orComplementary?. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
LionelR.Milgrom
13 TheEffectsofAgingonSleepArchitecture
inHealthySubjects. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93
GeorgDorffner,MartinVitr,andPeterAnderer
14 TheQuantumHumanCentralNeuralSystem. . . . . . . . . . . . . . . . 101
AthanasiosAlexiouandJohnRekkas
15 TheVitalForce“Reincarnated”:ModelingEntelechy
asaQuantizedSpinningGyroscopicMetaphor
forIntegratedMedicine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111
LionelR.Milgrom
16 BrainReserveandCognitiveTrainingintheElderly. . . . . . . . . . . 125
ParaskeviSakka
17 Non-pharmacologicalTreatmentsforPeoplewithDementia. . . . . 127
EleniS.Margioti
18 SOCIABLE:ASurfaceComputingPlatformEmpowering
EffectiveCognitiveTrainingforHealthyandCognitively
ImpairedElderly. . . . . . . . . . . .. . . . . . . . . . . . . . . . . . .. . . . . . . . 129
EvaDanassi
Index. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131
GeNeDis 2014 Information: Springer AEMB
GeNeDis 2014 Overview
The 1st World Congress on Geriatrics and Neurodegenerative Disease Research,
GeNeDis 2014 focused on recent advances in Geriatrics and Neurodegeneration,
rangingfrombasicsciencetoclinicalandpharmaceuticaldevelopments,providing
also an international forum for the latest scientific discoveries, medical practices,
andcareinitiatives.Leadingscientistsandexperts,students,physiciansandnurses,
professionals as well as industries representatives, and many other participants
discussed the latest major challenges, new drug targets, the development of new
biomarkers, imaging techniques, novel protocols for early diagnosis of neurode-
generative diseases, bioinformatics methods, and several other scientific achieve-
ments. While the European Union aims to strengthen the research and innovation
towards Horizon 2020, the translational research for healthy aging and
neurodegeneration will remove any barrier on multidisciplinary collaboration.
Novel approaches including biomarkers, stem cell therapy, protein misfolding,
immunotherapy, as well as developments in our understanding of the genetics,
the molecular mechanisms and signaling pathways contributing to neuronal dys-
function, nanotechnological products, and innovative computational methods will
offernewresearchdirectionsandstrategiesonfuturepreclinicalandclinicalstudies
on neurodegenerative diseases and further improvement of quality services on
rehabilitation and health education. Advanced information technologies have
been discussed concerning the various research, implementation, and policy, as
well as European and global issues in the funding of long-term care and medico-
socialpoliciesregardingelderlypeople.
Wecanresumethemajorobjectivesofthe1stWorldCongressonGeriatricsand
NeurodegenerativeDiseaseResearch,GeNeDis2014asfollows:
(cid:129) Topromotethescientificandresearchresultstotheresearchcommunitythrough
sharingandexchangingideas,experiences,andexpectationsfocusingonHealth
AgingandMentalWellnessinthenewdigitalera.
vii
viii GeNeDis2014Information:SpringerAEMB
(cid:129) To explore the beneficial (and not only) impact of scientific and technological
achievementsandfuturechallengesthatmayaffecttheHealthAgingandMental
Wellnessprocess.
(cid:129) To enhance the co-operation and the exchange of experiences and resources
amongorganizersofeventsandtheresearchcommunity,increasingfurtherthe
European dimension and added value of the activities of the Europe 2020 and
HORIZON2020.
(cid:129) Toincreasetheinterestofallthestakeholdersincontributingtotheresearchin
the field, while mental health is a basic human right, and is fundamental to all
human and social progress. It is a prerequisite to a happy and fulfilled life for
individual citizens, starting at birth, for functioning families and for societal
cohesion.
TheOrganizers
(cid:129) IonianUniversity,DepartmentofInformatics,BioinformaticsandHumanElec-
trophysiology,Greece
(cid:129) Ionian University, Department of Informatics, Computational Modeling Labo-
ratory,Greece
(cid:129) ScienceView,MemberoftheEuropeanScienceJournalistsEUSJA,Greece
TheCo-organizers
(cid:129) HellenicOpenUniversity,SchoolofScienceandTechnology,Greece
(cid:129) University of Salento, Department of Innovation Engineering, Laboratory of
AppliedMechanics,SectionofMechatronics,Italy
(cid:129) IonianUniversity,DepartmentofHistory,M.Sc.,inHistoricalResearch,Teach-
ingandNewTechnologies,Greece
(cid:129) RegionofIonianIslands,Greece
Scientific Program Committee
ConferenceChair
VlamosPanayiotis,DepartmentofInformatics,IonianUniversity,Greece
ConferenceVice-Chair
AlexiouAthanasios,DepartmentofInformatics,IonianUniversity,Greece
(cid:129) AcostaSandra,InstitutdeRechercheInterdisciplinaireenBiologieHumaineet
Mole´culaire,Belgium
(cid:129) AignerLudwig,ParacelsusMedizinischePrivatuniversita¨t,Austria
GeNeDis2014Information:SpringerAEMB ix
(cid:129) Alexopoulos Dimitrios, Dental Surgeon, Editorial Director Dentorama, Dental
JournalandDentalTribune,HygeiaHospital
(cid:129) AnagnostopoulosDimosthenis,HarokopeioUniversityofAthens,Greece
(cid:129) Ashraf Md Ghulam, King Fahd Medical Research Center, King Abdulaziz
University,SaudiArabia
(cid:129) Bilensoy Erem, Hacettepe U¨niversitesi Eczacılık Faku¨ltesi Farmaso¨tik
TeknolojiAnabilimDalı,Turkey
(cid:129) Bottalico Barbara, University of Pavia, European Center for Law, Science and
NewTechnologies,UniversityofPavia,Italy
(cid:129) ChrissikopoulosVassileios,IonianUniversity,Greece
(cid:129) ChatzidakiGeorgia,CorfuGeneralHospital,Greece
(cid:129) De Castro Fernardo, Grupo de Neurobiolog´ıa del Desarrollo-GNDe Hospital
NacionaldeParaple´jicos-SESCAM,Spain
(cid:129) DelabarJM,Universite´ ParisDiderot,France
(cid:129) Demetzos Costas, Dept. of Pharmaceutical Technology, Faculty of Pharmacy,
NationalandKapodistrianUniversityofAthens,Greece
(cid:129) D’MelloSantoshR.,UniversityofTexas,USA
(cid:129) Exarchos Themis, Department of Computer Science, University of Ioannina,
Greece
(cid:129) FjeldstedKatrin,PresidentStandingCommitteeofEuropeanDoctors
(cid:129) FotiadisDimitrios,UniversityofIoannina,Greece
(cid:129) Geoghegan-Quinn Maire, Commissioner of Research, Innovation and Science,
EU
(cid:129) GeorgiadisAdonis,MinisterForHealth,Greece
(cid:129) GiannakopoulosPanteleimon,Professor,ChairmanoftheDepartmentofMental
HealthandPsychiatry,UniversityHospitalsofGeneva,Switzerland
(cid:129) GhiatasAbraham,UniversityofTexas,USA
(cid:129) Gkigkitzis Ioannis, Departments ofMathematics and Biomedical Physics, East
Carolina,USA
(cid:129) GonosEfstathios,NationalHellenicResearchFoundation,InstituteofBiologi-
calResearchandBiotechnology,Greece
(cid:129) HadjinicolaouMaria,HellenicOpenUniversity,Greece
(cid:129) Haranas Ioannis, VDG Research and Development in Electromagnetic Theory
Applications,DepartmentofMathematics,EastCarolinaUniversity,USA
(cid:129) HuotilainenMinna,UniversityofHelsinki,Finland
(cid:129) IfantisIlias,HellenicNavalAcademy,Piraeus,Greece
(cid:129) KarabatsasKostantinos,GovernorofGeneralHospitalAchillopouleionofVolos
(cid:129) Karalis Vangelis, Faculty of Pharmacy, National Kapodistrian University of
Athens,Greece
(cid:129) KariotouFoteini,HellenicOpenUniversity,Greece
(cid:129) KontogeorgisGeorgios,TechnicalUniversityofDenmark
(cid:129) KoumoutsakosGeorgios,Commissioner,EU
(cid:129) KnyazevaMaria,LausanneUniversityHospital,Switzerland
(cid:129) LefkimmiatisKonstantinos, Department ofPhysiology Anatomy andGenetics,
UniversityofOxford