Gastrointestinal Anatomy and Physiology: The Essentials

200 Pages·2014·2.689 MB·English

by  John F. Reinus, Douglas Simon

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Gastrointestinal anatomy and physiology has its own resources website:
John F. Reinus and
www.wiley.com/go/reinus/gastro/anatomy
Douglas Simon
This companion website includes all figures from the book
www.wiley.com/go/gastro
Reinus_pbk_9780470674840.indd 1 04/02/14 15:00

Gastrointestinal Anatomy and Physiology
We dedicate this book to our teachers and students, and to our families, especially
our wives: Enid and Doreen, this book is for you with our undying gratitude for
your boundless love and support.
Gastrointestinal
Anatomy and
Physiology
The Essentials
EDiTED by
John F. Reinus, MD
Chief of Clinical Hepatology
Division of Gastroenterology and Liver Diseases
Montefiore Medical Center
Professor of Clinical Medicine
The Albert Einstein College of Medicine
bronx, Ny, USA
Douglas Simon, MD, FACG
Chief of Gastroenterology and Hepatology
Jacobi Medical Center
Professor of Clinical Medicine
The Albert Einstein College of Medicine
bronx, Ny, USA
This edition first published 2014 © 2014 by John Wiley & Sons, Ltd.
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Library of Congress Cataloging-in-Publication Data
Gastrointestinal anatomy and physiology : the essentials / edited by John F. Reinus, Douglas Simon.
p. ; cm.
includes bibliographical references and index.
iSbN 978-0-470-67484-0 (pbk. : alk. paper)
i. Reinus, John, editor of compilation. ii. Simon, Douglas, 1956– editor of compilation. [DNLM:
1. Digestive System–anatomy & histology. 2. Digestive System Physiological Phenomena. Wi 101]
QP145
612.3–dc23
2013034304
A catalogue record for this book is available from the british Library.
Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not
be available in electronic books.
Cover image: © Dream Designs image iD: 97229036
Cover design by Garth Stewart
Set in 9.5/13pt Meridien by SPi Publisher Services, Pondicherry, india
1 2014
Contents
Contributors, vi
Preface, ix
About the companion website, x
1 Structure and innervation of hollow viscera, 1
Laura D. Wood & Elizabeth A. Montgomery
2 Gastrointestinal hormones in the regulation of gut function in health
and disease, 15
John Del Valle
3 Gastrointestinal motility, 33
Ikuo Hirano & Darren Brenner
4 Gastrointestinal immunology and ecology, 46
Shehzad Z. Sheikh & Scott E. Plevy
5 Gastric physiology, 58
Mitchell L. Schubert
6 Structure and function of the exocrine pancreas, 78
James H. Grendell
7 Absorption and secretion of fluid and electrolytes, 92
Lawrence R. Schiller
8 Absorption of nutrients, 108
Lawrence R. Schiller
9 Hepatic structure and function, 129
Michelle T. Long & Lawrence S. Friedman
10 The splanchnic circulation, 149
Peter R. Kvietys & D. Neil Granger
11 Composition and circulation of the bile, 164
Allan W. Wolkoff
12 bilirubin metabolism, 173
Allan W. Wolkoff
index, 183
v
Contributors
Darren Brenner, MD
Assistant Professor of Medicine
Division of Gastroenterology
Northwestern University Feinberg School of Medicine
Chicago, iL, USA
John Del Valle, MD
Professor and Senior Associate Chair of Medicine
Department of internal Medicine
Division of Gastroenterology
University of Michigan Medical Center
Ann Arbor, Mi, USA
Lawrence S. Friedman, MD
Professor of Medicine
Harvard Medical School
Professor of Medicine
Tufts University School of Medicine
Assistant Chief of Medicine
Massachusetts General Hospital
boston, MA, USA
The Anton R. Fried, MD, Chair
Department of Medicine
Newton-Wellesley Hospital
Newton, MA, USA
D. Neil Granger, PhD
boyd Professor & Head
Department of Molecular & Cellular Physiology
LSU Health Sciences Center
Shreveport, LA, USA
James H. Grendell, MD
Professor of Medicine
School of Medicine
State University of New york at Stony brook
Stony brook, Ny, USA
Chief, Division of Gastroenterology, Hepatology & Nutrition
Winthrop University Hospital
Mineola, Ny, USA
vi
Contributors vii
Ikuo Hirano, MD
Professor of Medicine
Fellowship Program Director
Division of Gastroenterology
Northwestern University Feinberg School of Medicine
Chicago, iL, USA
Peter R. Kvietys, PhD
Professor of Physiology
College of Medicine
Alfaisal University
Riyadh, Saudi Arabia
Michelle T. Long, MD
Fellow, Division of Gastroenterology
boston University School of Medicine and
boston Medical Center
boston, MA, USA
Elizabeth A. Montgomery, MD
Professor of Pathology, Oncology, and Orthopedic Surgery
Department of Pathology
Johns Hopkins Hospital
baltimore, MD, USA
Scott E. Plevy, MD
Associate Professor
Departments of Medicine, Microbiology and immunology
University of North Carolina School of Medicine
Chapel Hill, NC, USA
Lawrence R. Schiller, MD
Professor of Medicine
Dallas Campus, Texas A&M College of Medicine
Attending Physician
Digestive Health Associates of Texas
Program Director
Gastroenterology Fellowship
baylor University Medical Center
Dallas, TX, USA
Mitchell L. Schubert, MD
Professor of Medicine and Physiology
Virginia Commonwealth University’s Medical College of Virginia
Chief, Division of Gastroenterology
McGuire Veterans Affairs Medical Center
Richmond, VA, USA
viii Contributors
Shehzad Z. Sheikh, MD, PhD
Assistant Professor of Medicine
Division of Gastroenterology and Hepatology
University of North Carolina School of Medicine
Chapel Hill, NC, USA
Allan W. Wolkoff, MD
The Herman Lopata Chair in Liver Disease Research
Professor of Medicine and Anatomy and Structural biology
Associate Chair of Medicine for Research
Chief, Division of Gastroenterology and Liver Diseases
Director, Marion bessin Liver Research Center
Albert Einstein College of Medicine and Montefiore Medical Center
bronx, Ny, USA
Laura D. Wood, MD, PhD
Assistant Professor of Pathology and Oncology
Department of Pathology
Johns Hopkins Hospital
baltimore, MD, USA