Future Perspectives in Gastroenterology Abstracts Poster Abstracts

182 Pages·2007·1.13 MB·English

Falk Symposium 161
Future Perspectives
in Gastroenterology
October 11–12, 2007
International Congress Center
Dresden
Abstracts
Poster Abstracts
©2007FalkFoundatione.V
Allrightsreserved.
Abstracts of Invited Lectures
Poster Abstracts

Falk Symposium 161

FUTURE PERSPECTIVES
IN GASTROENTEROLOGY

Dresden (Germany)
October 11–12, 2007

Scientific Organization:
M.C. Carey, Boston (USA)
P. Díte, Brno (Czech Republic)
A. Gabryelewicz, Bialystok (Poland)
V. Keim, Leipzig (Germany)
J. Mössner, Leipzig (Germany)
CONTENTS

Page

„Key Note Lecture“ in honor of Ernst Otto Riecken’s 75th birthday
Introduction
M. Zeitz, Berlin

Immune abnormalities that cause inflammatory bowel diseases
and biologic treatments that address these abnormalities
W. Strober, Bethesda 17 – 19

Session I

Inflammatory bowel diseases:
Summary of the workshop

Chair:
R.S. Blumberg, Boston
M.F. Neurath, Mainz

Cytokine pathways in IBD – The yin and the yang
C.O. Elson, Birmingham 23

New therapeutic strategies for chronic inflammatory bowel
diseases – Summary of the workshop „Intestinal inflammatory
mechanisms”
A. Stallmach, Jena 24 – 25

Session II

Esophagus and stomach

Chair:
P. Malfertheiner, Magdeburg

Physiology of acid secretion
E.M. El-Omar, Aberdeen 29 – 30

GERD – Endoluminal antireflux therapy
K. Caca, Ludwigsburg 31 – 32

Functional dyspepsia
H. Mönnikes, Berlin 33
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Session III

Lipoproteins and bile acids:
Physiology and pathophysiology

Chair:
F. Berr, Salzburg

Lipoprotein formation, structure and metabolism
D.E. Cohen, Boston 37

Chaperoning organic anion transporters through the hepatocyte
A.W. Wolkoff, Bronx 38

Pathophysiology of bile secretion
M.C. Carey, Boston 39 – 40

Session IV

Bile duct diseases

Chair:
T. Sauerbruch, Bonn

Pathogenesis of gallstone formation
F. Lammert, T. Sauerbruch, Bonn 43 – 44

Theories and techniques for resection of bile duct neoplasm –
Suggestions from the perspective of surgical anatomy and
pathology
W. Kimura, Yamagata 45 – 47

Surgical options in biliary diseases
P. Neuhaus, Berlin 48 – 49

Session V

Pancreatic physiology and pathophysiology

Chair:
J.C. Dagorn, Marseille

Mechanisms of pancreatic digestive enzyme secretion
J.A. Williams, Ann Arbor 53

Genes and the pancreas
H. Witt, Berlin 54 – 55
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Acute phase reaction of the pancreas
J.L. Iovanna, Marseille 56 – 57

Session VI

Pancreatic diseases

Chair:
P. Díte, Brno

Acute pancreatitis
G. Adler, Ulm 61

Chronic pancreatitis
D.C. Whitcomb, Pittsburgh 62

Gene expression analysis reveals the complexity of
pancreatic disease
C.D. Logsdon, Houston 63

„Key Note Lecture”
Introduction
M. Classen, Munich

The future of endoscopy in gastroenterology
J.F. Riemann, L. Helmstädter, Ludwigshafen 64

Session VII

Gastrointestinal oncology I

Chair:
M.C. Carey, Boston

Gastrointestinal endocrine tumors
B. Wiedenmann, Berlin 67

Gastrointestinal lymphoma
W. Fischbach, Aschaffenburg 68 – 69

Gastric cancer
M. Ebert, Munich 70

„Key Note Lecture”
Introduction
M.C. Carey, Boston
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Relationship between exocrine and endocrine pancreas
M. Otsuki, Kitakyushu 71

Session VIII

Gastrointestinal oncology II

Chair:
M.C. Carey, Boston

Pancreas
R.M. Schmid, Munich 75 – 78

Hepatocellular carcinoma
H.E. Blum, Freiburg 79

The role of the polyomavirus, JC virus, in the pathogenesis
of colorectal cancer
C.R. Boland, Dallas 80 – 81

„Key Note Lecture”
Introduction
A. Gabryelewicz, Bialystok

Gastroenterology in the tropics
R.K. Tandon, New Delhi 82

List of Speakers, Moderators and Scientific Organizers 83 – 86

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Poster Abstracts

Esophagus and Stomach: Physiology and Diseases

1. Helicobacter pylori in the gastric mucosa of children may induce apoptosis of
the helper lymphocytes
A. Kotlowska-Kmiec, M. Korzon, A. Bakowska, A. Szarszewski, B. Kaminska,
W. Radys, P. Landowski, J. Brodzicki, A. Liberek (Gdansk, PL)

2. pH monitoring in chronic respiratory disorders in children
G. Lesanu, V. Hurduc, C. Becheanu, C. Zapucioiu, C. Calcic, D. Pacurar,
R. Lesanu (Bucharest, RO)

3. Serum gastrin level in children with chronic gastritis with and without
Helicobacter pylori infection
G. Luczak, M. Czaja, A. Szarszewski, E. Kozielska, A. Delinska-Galinska,
K. Plata-Nazar, A. Borkowska, M. Korzon (Gdansk, Sztum, PL)

4. Hp infection in patients with gastric and duodenal ulcer and chronic liver
disease
P. Mitrut, A. Genunche-Dumitrescu (Craiova, RO)

5. New derivatives of nitric oxide (NO)-releasing aspirin in the mechanism of
gastric mucosal defense, comparison with classic (aspirin) NSAIDS
R. Pajdo, T. Brzozowski, D. Drozdowicz, A. Ptak-Belowska, S. Kwiecien,
M.W. Pawlik, S.J. Konturek, W.W. Pawlik (Cracow, PL)

6. Beneficial effect of esophagoprotection by proton pump inhibitor (PPI) and
tumor necrosis factor α (TNF-α) inhibition in rat model of acute reflux
esophagitis
M.W. Pawlik, T. Brzozowski, P.C. Konturek, R. Pajdo, Z. Sliwowski,
M. Mazurkiewicz, D. Drozdowicz, S.J. Konturek, W.W. Pawlik
(Cracow, PL; Erlangen, D)

7. Esophageal and systemic diseases due to aging
L.M. Susan, C. Banciu, S.R. Gotia, V.M. Ancusa, I. Romosan, C. Gorun
(Timisoara, RO)

Bile Ducts: Physiology and Diseases

8. Severe colitis following liver transplantation for primary sclerosing cholangitis
occurs mainly in young male adults with features of autoimmunity
O. Buchel, F. Nevens, J. Decaestecker, G. Van Assche, R. Aerts, J. Pirenne,
J. Fevery (Leuven, B)

9. Oxidative stress in extrahepatic cholestasis
K. Dagalp, C.N. Ercin, S. Bagci, Z. Yesilova, A. Aydin, A. Sayal, N. Karaeren
(Ankara, TR)
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10. Risk factors for gallstones in a patient population in Southern Transylvania
M. Deac, R. Elefterescu, R. Mihaila, O. Petrascu, A. Deac, R. Mihaila
(Sibiu, RO)

11. Malignancies developing in a cohort of 123 patients with primary sclerosing
cholangitis (PSC) during a median follow-up of 10 years
J. Fevery, O. Buchel, G.N. Lai, C. Verslype, W. Van Steenbergen, F. Nevens
(Leuven, B)

12. Gallstone pathogenesis: Reduced expression of OSTα and OSTβ as missing
link in ileal transporter function
S. Harsch, O. Renner, S. Schimmel, A. Strohmeyer, E.-F. Stange (Stuttgart, D)

13. Pharmacological boost of gastric emptying fails to improve the 13CO yield of
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the breath test with naturally 13C abundant corn groats
K. Jonderko, D. Bergel, M. Kaminska, A. Kasicka-Jonderko,
B. Blonska-Fajfrowska (Sosnowiec, PL)

14. Increase of the serum IgA and circulating immune complexes in the patients
with biliary diseases
S.A. Kosilko, N.M. Kozlova, J.L. Turumin (Irkutsk, R)

15. Increase of the blood glutathione in the patients with biliary diseases
V.I. Kulinsky, N.M. Kozlova, J.L. Turumin, Z.A. Leonova (Irkutsk, R)

16. Gallstone pathogenesis: Sequence analysis of the ileal bile acid transporter
gene
O. Renner, S. Harsch, E. Schäffeler, S. Schimmel, A. Strohmeyer, E.-F. Stange
(Stuttgart, D)

17. The potential role of endoscopic ultrasound (EUS) elastography in defining
thickening of ductus choledochus in primary sclerosing cholangitis (PSC)
N. Rustemovic, M. Opacic, S. Cukovic-Cavka, B. Vucelic (Zagreb, HR)

18. Cholestasis markers correlate with microhemorrheological disturbances
E.P. Sysoeva, E. Lukina, T. Solovjova, Z. Lichovetskaja, N. Khoroshko,
A.I. Vorobjev (Moscow, R)

19. Clinical aspects of the effective pathogenetic treatment of patients with chronic
acalculous cholecystitis
J.L. Turumin, N.M. Kozlova (Irkutsk, R)

20. Decrease of the portal blood flow in the patients with biliary diseases
H.E. Turumina, N.M. Kozlova, J.L. Turumin (Irkutsk, R)

21. Confirmation of the genes encoding the heterodimeric biliary cholesterol
transporter ABCG5/ABCG8 as gallstone susceptibility (Lith) genes in inbred
mice
H. Wittenburg, U. Kurtz, M.A. Lyons, D. Teupser, J. Mössner
(Leipzig, D; Perth, AUS)
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22. Structural and metabolic disturbances in rat brain histaminergic neurons under
cholestasis and their correction with Ursofalk®
S.M. Zimatkin, O.V. Baraban, S.V. Yemelyanchik (Grodno, WR)

Liver: Physiology and Diseases

23. Serological evidence for swine hepatitis E virus circulating in Taiwanese pig
herds
K.-H. Chang, C.-H. Wang, S.-H. Lee (Taipei, TJ; Tübingen, D)

24. Azathioprine-induced allergic hepatitis associated with thiopurine
methyltransferase (TPMT) genotype – Case report
S. Cukovic-Cavka, N. Bozina, Z. Krznaric, K. Grubelic-Ravic, M. Brinar,
J. Sertic, B. Vucelic (Zagreb, HR)

25. Diabetes type 2 and chronic viral C hepatitis
D. Damian, M. Grigorescu, M.D. Grigorescu, T. Zaharie, T. Mocanu
(Cluj-Napoca, RO)

26. Extrahepatic manifestations in chronic viral C hepatitis
D. Damian, M. Grigorescu (Cluj-Napoca, RO)

27. Perspectives of gastroenterological conservative and miniinvasive treatment of
liver echinococcosis
K. Kalinova, A. Ilieva (Stara Zagora, Pleven, BG)

28. The efficacy or ursodeoxycholic acid in cholestasis of pregnancy (ICP) –
A review of RCTs trials
E. Kuchar, L. Szenborn, T. Czerniak (Wroclaw, PL)

29. Genetic polymorphism of hemocoagulation factors in patients with prehepatic
portal hypertension
E. Lukina, E.P. Sysojeva, E. Voronkova, E. Kitsenko, E. Lubivy, G. Sukhanova,
S. Vasiljev (Moscow, R)

30. The prevalence of gallstones in chronic liver disease
D. Neagoe, G. Ianosi, T. Ciurea, C. Vere, M. Bezna, F. Racanel, A. Amzolini
(Craiova, RO)

31. Prevalence and characterization of SEN virus strains isolated from Taiwanese
patients with elevated liver enzymes
S.-Y. Tschen, S. Schleicher, S.-M. Lin, C.-C. Lee, A. Normann, C.-H. Wang,
B. Flehmig (Tübingen, D; Taipei, TJ)

32. MicroRNA 122 is overexpressed in primary liver nodules arising in hepatitis C
H. Varnholt, M. Scheffler, E. Konze, A. Manav, V. Dries, F. Schulze,
I. Wedemeyer, P. Schirmacher, U. Drebber, H.P. Dienes, M. Odenthal
(Cologne, Mannheim, Heidelberg, D)
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