Functional tasks exercise for older adults with cognitive impairment at risk of Alzheimer's disease

315 Pages·2014·1.8 MB·English

ResearchOnline@JCU

This file is part of the following reference:

Law, Lawla Lan Fong (2013) Functional tasks exercise
for older adults with cognitive impairment at risk of
Alzheimer's disease. PhD thesis, James Cook University.

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http://researchonline.jcu.edu.au/31456/

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http://researchonline.jcu.edu.au/31456/
Functional Tasks Exercise for Older Adults with
Cognitive Impairment at Risk of Alzheimer’s
Disease

Thesis submitted by
Lawla Lan Fong LAW
PDOT, BBA, PgCert (Gerontology), MSc OSH

July 2013

For the degree of Doctor of Philosophy
In the School of Public Health, Tropical Medicine and
Rehabilitation Sciences
James Cook University

I
STATEMENT OF ACCESS
I, the undersigned, author of this work, understand that James Cook
University will make this thesis available for use within the University
Library and via the Australian Digital Theses network, for use elsewhere.
I understand that, as an unpublished work, a thesis has significant
protection under the Copyright Act and I do not wish to place further
restrictions on this work.
_ _____ 5 August 2013
Signature LLaawwllllllllllllllllllllllllllllllllllllllllllllllaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa LLLLLLLLLLLLLaaww Date
II
STATEMENT OF SOURCES DECLARATION

I declare that this thesis is my own work and has not been submitted in any
form for another degree or diploma at any university or other institution of
tertiary education.
Information derived from the published or unpublished work of others has
been acknowledged in the text and a list of references is given.
Every reasonable effort has been made to gain permission and
acknowledge the owners of copyright material. I would be pleased to hear
from any copyright owner who has been omitted or incorrectly
acknowledged.

_______________________________________ 5 August 2013
Signature LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaawwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwllaa Law Date

III
STATEMENT ON THE CONTRIBUTION OF OTHERS

I declare that all persons whom have contributed to this thesis have been
included as co-authors for published papers or are acknowledged below.

The contribution of my three supervisors; Dr. Fiona Barnett, Professor
Matthew Yau and Professor Marion Gray throughout the research, in the
publication of papers and in the completion of this thesis is greatly
appreciated and acknowledged.

The author has received no external financial assistance for this thesis. All
expenses have been covered by James Cook University, School of Public
Health, Tropical Medicine and Rehabilitation Sciences or by the author

IV
List of Research Output and Jointly Authored Works Contained in
This Thesis

Published Paper
1. Law LL, Barnett F, Yau MK, Gray MA (2012). Measures of everyday
competence in older adults with cognitive impairment: A systematic review. Age
and Ageing, 41(1), 9-16. doi: 10.1093/ageing/afr104
(cid:289)
Author contribution: L. Law was involved in the design of the study, systematic
search, data extraction and analysis as well as the writing of the manuscript. F.
Barnett assisted in the design of the study, data extraction and writing of the
manuscript. M. Gray assisted in the writing of the manuscript. M. Yau assisted in
the writing of the manuscript.

2. Lawla LF Law, Fiona Barnett, Marion A Gray, Matthew K. Yau. Effects of
combined cognitive and exercise interventions on cognition in older adults with
and without cognitive impairment: A Systematic Review. (Submitted to
International Psychogeriatrics, currently under review)
(cid:289)
Author contribution: L. Law was involved in the design of the study, systematic
search, data extraction and analysis as well as the writing of the manuscript. F.
Barnett assisted in the design of the study, data extraction and writing of the
manuscript. M. Gray assisted in the writing of the manuscript. M. Yau assisted in
the writing of the manuscript.
(cid:289)
3. Lawla LF Law, Fiona Barnett, Matthew K. Yau, Marion A Gray (2013).
Development and initial testing of Functional Task Exercise on Older Adults with
Cognitive Impairment at Risk of Alzheimer’s Disease –FcTSim program a
feasibility study. Occupational Therapy International, June 2013, early view
published online.

Author contribution: L. Law was involved in the design of the study, data collection,
statistical analysis and the writing of the manuscript. F. Barnett assisted in the
design of the study and writing of the manuscript. M. Yau assisted in the writing of
the manuscript. M. Gray assisted in the writing of the manuscript.
(cid:289)
(cid:289)
V
4. Law LL, Barnett F, Gray MA, Yau MK. Translation and validation of Chinese
version of Problems in Everyday Living (PEDL) Test in patients with Mild
Cognitive Impairment. (Submitted to International Psychogeriatrics, currently
under review)
(cid:289)
Author contribution: L. Law was involved in the design of the study, data collection,
statistical analysis and the writing of the manuscript. F. Barnett assisted in writing
of the manuscript. M. Yau assisted in the writing of the manuscript. M. Gray
assisted in the writing of the manuscript.
(cid:289)
5. Law LL, Barnett F, Yau MK, Gray MA. Effects of Functional Tasks Exercise on
Older Adults with Cognitive Impairment at Risk of Alzheimer’s Disease – A
randomized controlled trial (Submitted to Alzheimer’s & Dementia, currently
under review)

Author contribution: L. Law was involved in the design of the study, data collection,
statistical analysis and the writing of the manuscript. F. Barnett assisted in the
design of the study, statistical analysis and writing of the manuscript. M. Yau
assisted in the writing of the manuscript. M. Gray assisted in the writing of the
manuscript.

Conference Presentation

1. Law LL, Barnett F, Yau MK, Gray MA (3013). Effect of Functional Tasks
Exercise Program on Older Adults with Cognitive Impairment at Risk of
Alzheimer’s Disease - A pilot study. Conference paper presentation at the
Occupational Therapy Australia National Conference July 2013

VI
Published Works Incorporated into The Thesis

1. Lawla LF Law, Fiona Barnett, Marion A Gray, Matthew K. Yau. Effects of
combined cognitive and exercise interventions on cognition in older adults with
and without cognitive impairment: A Systematic Review. (Submitted to
International Psychogeriatrics, under review)

Incorporated as Chapter 2

2. Law LL, Barnett F, Yau MK, Gray MA (2012). Measures of everyday competence
in older adults with cognitive impairment: A systematic review. Age and Ageing,
41(1), 9-16. doi: 10.1093/ageing/afr104

Incorporated as Chapter 3

3. Lawla LF Law, Fiona Barnett, Matthew K. Yau, Marion A Gray (2013).
Development and initial testing of Functional Task Exercise on Older Adults with
Cognitive Impairment at Risk of Alzheimer’s Disease –FcTSim program a
feasibility study. Occupational Therapy International, June 2013, early view
published online. DOI: 10.1002/oti.1355

Incorporated as Chapter 4

4. Law LL, Barnett F, Gray MA, Yau MK (In press). Translation and validation of
Chinese version of Problems in Everyday Living (PEDL) Test in patients with
Mild Cognitive Impairment. International Psychogeriatrics.

Incorporated as Chapter 5

5. Law LL, Barnett F, Yau MK, Gray MA. Effects of Functional Tasks Exercise on
Older Adults with Cognitive Impairment at Risk of Alzheimer’s Disease – A
randomized controlled trial (Submitted to Alzheimer’s & Dementia, under
review)

Incorporated as Chapter 6
VII
DECLARATION ON ETHICS

The research presented and reported in this thesis was conducted within the
guidelines for research ethics outlined in the National Statement on Ethical
Conduct in Research Involving Humans (2007) and the James Cook
University Code for the Responsible Conduct of Research (2007). The
research methodology outlined here received clearance from the James
Cook University Human Research Ethics Committee (approval number:
H4269) and the Hospital Authority Ethics Committee, Hong Kong
(approval number: KC/KE-11-0097/ER-3).

______________________________________ 5 August 2013
Signature LLaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaawwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwwllaa LLaw Date

VIII
ACKNOWLEDGEMENTS
I wish to start this acknowledgement to all those who have assisted and supported me in
finalizing this research by thanking God for his wisdom and blessing that have enabled
me to get through many long and hard days when doubt and uncertainty held sway.
To my supervisor, Dr. Fiona Barnett, I would like to express my sincerest gratitude for
her continuous guidance, support and encouragement throughout my candidature which
has enabled me to overcome many obstacles and progress towards the final destination.
She has always given me prompt and unwavering support despite her many other
academic and professional commitments. Today’s achievement would not have been
reached without her dedication, encouragement, mentorship and support. I will
remember: I need to have a thick skin to get the work published!
I would like to extend my warm and heartfelt thanks to my co-supervisors, Professor
Matthew Yau and Professor Marion Gray. Thanks to Professor Matthew Yau for
encouraging me to take this opportunity to grow as a researcher and scholar. The
experience has been challenging but rewarding. His professional experience and
invaluable suggestions guided me throughout the course of this work, supplemented by
his pain-staking effort in reviewing and polishing my draft works. Thanks also to
Professor Marion Gray for her meticulous guidance. She never failed to give insightful
opinions and positive feedback to my work.

I cannot thank my supervisor and co-supervisors enough for the continuous input and
effort which are indispensable to the accomplishment of this thesis.

Further, I greatly appreciate the kind assistance of the staff in the United Christian
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