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Food Contaminants and Residue Analysis, Volume 51 (Comprehensive Analytical Chemistry) PDF

848 Pages·2008·7.72 MB·English
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COMPREHENSIVE ANALYTICAL CHEMISTRY 5 1 VOLUME ADVISORY BOARD Joseph A. Caruso University of Cincinnati, Cincinnati, OH, USA Hendrik Emons Joint Research Centre, Geel, Belgium Gary Hieftje Indiana University, Bloomington, IN, USA Kiyokatsu Jinno Toyohashi University of Technology, Toyohashi, Japan Uwe Karst University of Mu¨nster, Mu¨nster, Germany Gyo¨rgy Marko-Varga AstraZeneca, Lund, Sweden Janusz Pawliszyn University of Waterloo, Waterloo, Ont., Canada Susan Richardson US Environmental Protection Agency, Athens, GA, USA Elsevier Radarweg29,POBox211,1000AEAmsterdam,TheNetherlands LinacreHouse,JordanHill,OxfordOX28DP,UK Firstedition2008 Copyrightr2008ElsevierB.V.Allrightsreserved Nopartofthispublicationmaybereproduced,storedinaretrievalsystemortransmittedinany form orby any meanselectronic,mechanical, photocopying,recording orotherwise without the priorwrittenpermissionofthepublisher Permissions maybesought directlyfromElsevier’sScience&Technology Rights Departmentin Oxford,UK:phone(+44)(0)1865843830;fax(+44)(0)1865853333;email:[email protected]. Alternatively you can submit your request online by visiting the Elsevier web site at http:// www.elsevier.com/locate/permissions,andselectingObtainingpermissiontouseElseviermaterial Notice Noresponsibilityisassumedbythepublisherforanyinjuryand/ordamagetopersonsorproperty as a matter of products liability, negligence or otherwise, or from any use or operation of any methods,products,instructionsorideascontainedinthematerialherein.Becauseofrapidadvances inthemedicalsciences,inparticular,independentverificationofdiagnosesanddrugdosagesshould bemade BritishLibraryCataloguinginPublicationData AcataloguerecordforthisbookisavailablefromtheBritishLibrary LibraryofCongressCataloging-in-PublicationData AcatalogrecordforthisbookisavailablefromtheLibraryofCongress ISBN: 978-0-444-53019-6 ISSN:0166-526X ForinformationonallElsevierpublications visitourwebsiteatbooks.elsevier.com PrintedandboundinHungary 0809101112 10987654321 Wilson & Wilson’s COMPREHENSIVE ANALYTICAL CHEMISTRY FOOD CONTAMINANTS AND RESIDUE ANALYSIS 51 VOLUME Edited by YOLANDA PICO´ Laboratori de Bromatologia i Toxicologia Facultat de Farmacia Universitat de Valencia Av. Vicent Andre´s Estelle´s s/n. 46100 Burjassot Valencia, Spain Amsterdam(cid:2)Boston(cid:2)Heidelberg(cid:2)London NewYork(cid:2)Oxford(cid:2)Paris(cid:2)SanDiego SanFrancisco(cid:2)Singapore(cid:2)Sydney(cid:2)Tokyo Wilson & Wilson’s COMPREHENSIVE ANALYTICAL CHEMISTRY Edited by D. BARCELO´ Research Professor Department of Environmental Chemistry IIQAB-CSIC Jordi Girona 18-26 08034 Barcelona Spain This page intentionally left blank CONTENTS Contributors to Volume 51 xiii Volumes in the Series xix Preface xxiii Series Editor’s Preface xxv 1. Challenges in Chemical Food Contaminants and Residue Analysis 1 Michel W.F.Nielenand HansJ.P. Marvin 1. Introduction 2 2. EmergingContaminants 7 3. MaskedContaminants 14 4. UnknownBioactive Contaminants 15 5. EmergingTechnologies 18 6. Validation and QA/QCChallenges 22 7. Conclusionsand FutureTrends 24 Acknowledgements 25 References 25 2. International Regulations on Food Contaminants and Residues 29 IoannisS. Arvanitoyannis 1. Introduction toEU andUSA Legislation 29 2. Topics/Categories Covered under EULegislation 31 3. Topics/Categories Covered under USALegislation 63 References 73 3. Guidelines on Quality Implementation for Analytical Methods 77 Sergio Caroli 1. Introduction 77 2. The RoleofQuality 78 3. Conclusions 86 References 87 vii viii Contents 4. Immunochemical and Receptor Technologies: The Role of Immunoassay, Immunoaffinity Chromatography, Immunosensors and Molecularly Imprinted Polymeric Sensors 91 Marinel (cid:2)la Farre´,Elena Mart´ınez andDamia` Barcelo´ 1. Introduction 92 2. Definitionsand Concepts 93 3. Immunoassay Formats 95 4. Immunoassay Development 96 5. Immunochemical Technologies 101 6. Biomimics: Molecularly ImprintedPolymers (MIPs) 113 7. Commercial Instrumentation andFuture Perspectives 122 References 125 5. Advanced Sample Preparation Techniques for the Analysis of Food Contaminants and Residues 131 Pat Sandra,Frank David andGerd Vanhoenacker 1. Introduction 131 2. Sample Preparation MethodsforVOCs 133 3. Sample Preparation MethodsforSVOCs andNVOCs 138 4. Fractionation and Clean-Up 162 5. Evaporation 170 6. Derivatization 170 7. Conclusion 171 References 172 6. Recent Developments in Chromatographic Techniques 175 Katerina Mastovska 1. Introduction 175 2. Fast Chromatographic Separation 176 3. Two-Dimensional Chromatographic Separation 188 4. OvercomingAdverse MatrixEffects 191 5. Future Trends 196 References 197 7. New Approaches in Mass Spectrometry 201 Yolanda Pico´ 1. Introduction 201 2. High Resolutionand AccurateMassAnalysers 204 3. Tandem MassSpectrometry 211 4. High ResolutionMassSpectrometers inTandem 219 5. Conclusionsand FutureTrends 227 References 228 Contents ix 8. Capillary-Based Separation Techniques 231 Peter Viberg 1. Introduction 231 2. Miniaturization andthe Capillary Format 232 3. Capillary LiquidChromatography 233 4. Capillary Electroseparations 235 5. DetectionTechniques inCapillary-Based Separations 250 6. Automation andOn-Line/In-Capillary CoupledSolid-Phase Extraction inCapillary Electrophoresis 251 7. ApplicationsinDetermination ofFoodContaminants UsingCapillary Electrophoresis 252 References 253 9. Pesticide Residues 257 Anna Sannino 1. Introduction 257 2. Physical andChemical Properties 258 3. HealthEffects 259 4. Analytical Methods 272 5. Instrumental Determination 278 6. LC-MS-MS Applications 295 7. Conclusionsand FutureTrends 301 References 302 10. Veterinary Drug Residues 307 Sherri B. Turnipseedand WendyC. Andersen 1. Introduction 307 2. Physical andChemical PropertiesAffecting Analytical Methodology 313 3. HumanHealth Effects fromVeterinary Drug Residues 315 4. Analytical Methods 317 5. OccurrenceinFood 328 6. FutureTrends 329 References 332 11. Analytical Strategies to Control the Illegal Use of Banned Growth Promoters in Meat Producing Animals 339 Bruno LeBizec,Jean-Philippe Antignac andGaud Pinel 1. Introduction 339 2. ChemicalProperties, Health effects 340 3. Analytical Methods 342 4. OccurrenceinFoods 357 5. FutureTrends 358 References 358

Description:
Food Contaminants and Residue Analysis treats different aspects of the analysis of contaminants and residues in food, and highlights some current concerns facing this field. The content is initiated by an overview on food safety, the objectives and importance of determining contaminants and residues
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