Table Of Content

PII: S0278-6915(99)00095-2 Index of Authors Abel S., 497 Chiang M., 141 Gembardt C., 165 Adams T. B., 249 Chiarello P. G., 929 Gerberick G. F., 327 Agrawal R. C., 975 Chipman J. K., 375 German J. B., 585 Ahokas J., 321 Chou M. W., 1053 Gescher A., 375 Ahr H. J., 979, 997 Chu I., 21 Gettings S. D., 47, 209 Akagi A., 1065 Chung H. L., 169 Gil-Martin E., 941 Amacher D. E., 831 Chung J. G., 761 Gingell R., 825 Andreoli C., 155 Chung K.-T., 1053 Gordon D. R., 429 Arcadi F. A., 963 Ciacci-Zanella J. R., 791 Gott D., 849 Arnold D. L., 771 Cifone M. A., 127 Grasso P., 1015 Ataya D. G., 1085 Clifford M. N., 617 Gray K., 14] Athar M., 485 Coenen T. M. M., 781 Greer D. B., 249 Attias L., 37 Cokelaere M., 13 Greger J. L., 505 Aughton P., 781 Collins H. E., 585 Gu L.-Q., 563 Avalos J. T., 183 Collins T. F. X., 397, 673, 1117 Guest D., 521 Ayres P. H., 191 Costa C., 963 Gupta S., 21 Costa G., 963 Guseva N. V., 1 Bach P. H., 335 Crebelli R., 155 Baijal P. K., 601 Hager M., 637 Bagar S. M., 1125 Daenens P., 13 Hagiwara A., 299 Bar E. A., 1139 Das M., 437 Hall R., 529 Barratt M. D., 233 David R. M., 429, 609 Hall R. L., 111 Barton P. T., 455, 647 Day A. J., 623 Hall-Manning T. J., 233 Basketter D. A., 199, 233, 327 De B., 937 Hansen D. K., 397, 673 Beamand J. A., 455, 647 Dearman R. J., 199 Hasegawa R., 1043 Bernard L. G., 429 Deckardt K., 165 Hawley R. S., 585 Bernardo-Filho M., 1079 Decuypere E., 13 Hayward S., 771 Bernt W. O., 1139 Deisinger P. J., 521 Helsby N. A., 375 Bestervelt L. L., 61 Delzenne N. M., 555 Henwood S. M., 135 Bird R. P., 601 Dethloff L. A., 61 Hepburn P. A., 747 Black T., 1117 Doolittle D. J., 183, 191 Hernaux N. A., 555 Black T. N., 397, 673 Doull J., 249 Hildebrand B., 165 Blair M., 121 Drugarin D., 245 Hines J., 233 Blankemeyer J. T., 383 Dunkelberg H., 897 Hintze K. L., 47, 209 Blonk C. G., 663 Durnev A. D., 1 Hiramoto K., 305 Boatman R. J., 825 Dutta A., 937 Hirose M., 299 Bodnar J. A., 169 Dwivedi P. D., 437 Hofmann P., 637 Hojo H., 421 Bolte H. F., 575 Bombick D. W., 183, 191 Edenharder R., 637, 897 Holland G. H., 233 Bomhard E., 979, 997 El-Nezami H., 321 Hori M., 1073 Bootman J., 849 English J. C., 609 Hosono A., 805 Borgerding M. F., 169 Enzmann H., 979, 997 Howard P. C., 397, 673 Borzelleca J. F., 1139 Eppley R. M., 397, 673 Howes D., 711, 719 Boysen B. G., 111, 135 Hsieh C. L., 761 Brooks K., 409 Faulkner B. C., 591 Hu M.-L., 755 Brown E. D., 279, 289 Feder P. I., 47, 209 Huang H.-P., 631 Brown R. D., 1107 Felton J. S., 279, 289 Hwang D. F., 239 Brunnemann K. D., 997 Felzenszwalb I., 1079 Bryant M. A., 397, 673 Fernandez-Briera A., 941 latropoulos M., 979, 997 Bu-Abbas A., 617 Field W. E., 111 Iglesias A. C., 929 Burdock G. A., 347 Fitzpatrick D. W., 601, 947, 955 Ikeda G. J., 907 Burkhardt J. E., 831 Flamm G., 1139 Imperatore C., 963 Butterworth L. F., 1107 Flo G., 13 Inoue R., 467 Ford R. A., 249 Inoue T., 1043 Caldeira-de-Araujo A., 1079 Fort D. J., 591 Ioannides C., 315, 617 Calvo P., 941 Foster W., 21 Iqbal M., 485 Frangart J., 637 Ito A., 697 Cao J., 1061 Carere A., 155 Freeman C., 705 Itoh N., 811 Chagnon M., 915 Friedman M., 383 Ivett J. L., 127 Chang W.-C., 631 Fujimoto N., 697 Izumi K., 1065 Chappel C. I., 81, 101, 111, 121, 135, Fujita H., 467 141, 915 Furusawa N., 811 Jagerstad M. I., 879 Chen G. W., 761 Furuya M., 445 James C. T., 719 Chen I. L., 513 Jeffery E. H., 365 Cheng H. M., 239 Garleb K. A., 1085 Johansson M. A. E., 879 Cheng W.-Q., 563 Gelderblom W. C. A., 497 Jones C., 791 13 14 Index of Authors Jordao Jr A. A., 929 McGuire P. F., 771 Rogers J. C., 169 Juberg D. R., 429 McWilliams M. L., 383 Rorie J., 1117 Mehrotra N. K., 1125 Rorie J. I., 397, 673 Kai S., 1043 Meijer G. W., 663 Rosenkranz H. S., 687 Kaneda M., 421 Merrill Jr A. H., 791 Ross I. A., 907 Kang J. J., 513 Miller D., 771 Rossi S., 279 Kankaanpaa P., 321 Minami T., 1065 Rothman N., 279, 289 Kato T., 305 Mitchell S. C., 923 Roy G., 697 Katz G. V., 429 Miyake T., 841 Ruggles D. I., 397, 673 Kawamura O., 445 Modderman J., 1139 Rumbeiha W. K., 1095 Kennepohl E., 1139 Moreno F., 929 Kerkhoff G., 897 Morgan W. T., 183 Sadrieh N., 1033 Kerr D., 375 Morinaga T., 1073 Saha A., 73, 937 Khanna S. K., 437 Morrison C. C., 169 Sai K., 1043 Kikugawa K., 305 Most E., 7 Sakaki S., 1073 Kim S. K., 655 Moyer C., 609 Salemi M., 963 Kim Y. C., 655, 655 Mukherjee A., 73, 937 Salminen S., 321 Kimber I., 199, 327 Mukhopadhyay M. J., 73, 937 Salmon C. P., 279, 289 King R. S., 1033 Munro I. C., 249, 529, 1139 Sano N., 1065 Kingston S., 365 Munson A. E., 1107 Sapienza P. P., 907 Kitano M., 811 Murli H., 183 Schardein J. L., 135 Kitts D. D., 543 Murray F. J., 591 Schlatter C., 971 Kligman A. M., 867 Musgrove D. L., 1107 Schlueter G., 979, 997 Kligman L. H., 867 Myhr B. C., 127 Schneider F., 245 Klimisch H.-J., 165 Schomaker S. J., 831 Klopman G., 687 Nagao M., 467 Schramm D. D., 585 Knize M. G., 279, 289 Nakatani T., 697 Schut H. A. J., 1033 van de Kooi A. J., 663 Newberne P., 249 Scimeca J. A., 391 Kotkoskie L. A., 705 Newton P. E., 575 Seki H., 1073 Kiihn E., 13 Nishimori T., 1073 Seredenin S. B., | Kumar S., 975 Shackelford M. E., 397, 673 Kuratko C. N., 819 O’Donoghue J. L., 609 Shephard G. S., 497 Kuroda K., 811 Obatomi D. K., 335 Shephard S. E., 971 Kurokawa Y., 1043 Olejnik N., 397, 673, 1117 Shibamoto T., 841 Kusamran W. R., 475 Oreshchenko A. V., 1 Shirai T., 299 Otsuka H., 1065 Shubik P., 529 Laborde J. B., 397 Ozaki A., 811 Shukla Y., 1125 Laborde J. B., 673 Simmons D. F., 169 Lake B. G., 455, 647 Pacchierotti F., 155 Sinha R., 279, 289 Lawlor T. E., 127 Pakhale S. S., 1131 Skog K. I., 879 Lecavalier P., 21 Pallauf J., 7 Smith M., 739, 743 Lee M.-J., 631 Palmer T. E., 135 Smith M. R., 747 Levander O. A., 279, 289 Paquet A., 771 Smith R. L., 249, 923 Lewis S., 825 Patmore S. J., 61 Smith S. Y., 915 Li X., 305 Paunescu V., 245 Snyderwine E. G., 1033 Liang R., 563 Pelielo de Mattos J. C., 1079 Snyman §S. D., 497 Lin J., 445 Perry L. G., 521 Sprando R. L., 397, 673, 1117 Lin J. G., 761 Pestka J. J., 409, 1095 Staack R., 365 Lin W.-L., 631 Poon R., 21 Stanescu D. I., 245 Lin Y.-L., 631 Portoghese P. S., 249 Stazi A. V., 37 Liu D.-L., 563 Price R. J., 455, 647 Stover E. L., 591 Liu J. W., 1061 Procter B. G., 101 Suber R. L., 575 Llewellyn G. C., 1107 Propst T. L., 591 Sugiura Y., 445 Lordo R. A., 47, 209 Putnam K., 191 Sutherland J. E., 505 Lu Z., 1053 Putnam K. P., 183 Swanevelder S., 497 Lynch B. S., 1139 Swanson C, A., 279 Rahi M., 575 Ma L., 563 Ramsey M. J., 467 Takenaka H., 1073 MacKenzie K. M., 111, 135 Rapisarda A., 963 Tamano §S., 299 Macri C., 37 Ratanavila A., 475 Tanaka H., 299 Maita K., 421 Rauscher R., 637 Tanaka N., 1073 Maki S., 445 Rayburn J. R., 383 Tanimura A., 1043 Malcolm S., 771 Reed Bombick B., 183, 191 Taper H. S., 555 Mangan P. P., 169 Rennie G., 233 Tatu C. A., 245 Mann A. H., 1015 Report M., 145 Tepsuwan A., 475 Mantovani A., 37 Revell P., 233 Teramoto S., 421 Maranghi F., 37 Reynolds R. C., 81, 95 Thomas B., 2! Marchese A., 963 Rhodes D., 279, 289 Tierney B. M.., 61 Marin-Martinez M. L., 409 Rhodes M. J. C., 623 Timmer W. G., 663 Maru G. B., 1131 Ricciardi C., 37 Tinkler J., 849 Masuda T., 811 Rimbach G., 7 Tisdel P. J., 111, 135 Matsushima T., 467 Risner C. H., 169 Tjurina L. S., |! McCay J. A., 1107 Ritskes-Hoitinga J., 663 Topping D. C., 429 Index of Authors Totman L. C., 609 Wagner B. M., 249 Wilson R., 711, 719, 739, 743, 747 Tredger J. M., 455 Walker R., 315, 617 Wingate D. E., 169 Trimarchi G. R., 963 Wallig M. A., 365 Winkler L. S., 169 Trucksess M. W., 397, 673 Walter A., 7 Wolf B. W., 1085 Tsai H.-H., 755 Walton K., 315 Wong S.-S., 409 Tsuchida M., 1073 Wang C.-J., 631 Woods L. A., 249 Tucker J. D., 467 Wang E., 791 Wang J., 947, 955 Yamada A., 1073 —_ Wang L. C., 239 Yamaguchi H., 811 nage ag re Watanabe H., 697 Yamaguchi Y., 1073 eno Y., 445 Uhrig M. S.. 169 Watarai K., 1073 Yan D., 1095 Weil C. S., 249 Yannai S., 623 Umemura T., 1043 a Weissenberg M., 383 Yao D.-S., 563 Ve, TS Wendelboe F. N., 169 Yen-Yang H. F., 513 West A. J., 135 Yoshida M., 305 Valli V. E., 21 van der Westhuizen L., 497 Young R. R., 127 Van Boven M.., 13 Weststrate J. A., 663 Van Schie B. J., 711 Wheeler K. B., 1085 Zandee J. C., 61 Vannucchi H., 929 White Jr K. L., 1107 Zapponi G. A., 37 Vermaut S., 13 Wiersma A., 663 Zhang A. Q., 923 Verschuren P. M., 663 Wijewickreme A. N., 543 Zhang Y. P., 687 Villani P., 155 Williams G. M., 979, 997 Zhao Y., 1061 Vlaovic M. S., 429 Williamson G., 623 Zhou H.-R., 409 Volgareva G. M., | Wilson J. R., 947, 955 Zijno A., 155 Vollmuth T. A., 591 Wilson N. H., 575 Zucoloto S., 929 PII: S0278-6915(99)00083-6 Index of Subjects A(a)C (2-Amino-9H-pyrido-[2,3-bjindole) DNA adduct 3.V ... flaxseed 3.1II ... ginseng 9/10.IV ... green tea formation and mammary gland bioassay 1033 3.VI ... maltitol 8.1 ... olive oil 8.1] Abortion petrochemicals and 3.VIII ... spontaneous and Antimony NOAEL (no-observed-adverse-effect level) in drinking water quality 6.V drinking water 21 ... subchronic toxicity in drinking Acesulfame-K chromosome damage and 3.1 water in rats 21 ... toxicity 3.X Acetochlor fertility and 78 Antimutagenicity Monascus pigments 77 Acrylates respiratory diseases 3.1X Apoptosis y-hexachlorocyclohexane induction and intra- Acrylic acid reproduction and 152 cellular Ca?* release pathway 513 Acylamino acids antibacterial agents properties of myris- Aquacoat" ECD ethyl cellulose toxicity and aequous toyl-methionine 771 dispersion 705 ADMUL WOL see Polyglycerol polyricinoleate (PGPR) Armillariella tabescens aflatoxin B, detoxification by Aflatoxin B, binding by Lactobacillus rhamnosus 321 ... enzymes of 563 detoxification by Armillariella tabescens enzymes 563 Aroclor 1254 Rhesus offspring sex ratios 451 Agaricus bisporus extract mutagenicity after baking/freeze- Arsenic stroke and 79 drying 315 Artherosclerosis n-3 polyunsaturated fatty acids (PUFA) Agaritine DNA binding 971 and diet 663 Air fresheners irritants 8.1V Arthritis avocado, treatment 4.III ... cosmetic mineral oils and 4.1V Air pollution new mutagen 3.XI Arylamine N-acetyltransferase activity in human colon Albania adult mortality rates 3.1V cancer cells and diallyl disulfide 761 Albumin bovine serum, allergy 4.III Asbestos environmental exposure and cancer 3.IX ... non- Alcoholization free-choice drinking water ingestion in rats occupational risks 9/10.1X 941 Aspartame mutagenicity 12.1 Alcohol breast cancer and 4.1 ... heaith benefits 149 ... Aspergillus niger safety evaluation of amino peptidase Helicobacter pylori 150 from 781... safety testing of aminopeptidase 12.1 Algae Nostoc flagelliforme safety evaluation as potential Aspirin digestive tract cancer 6.V food 1073 Assays mammary gland and A(a)C DNA adduct for- Alkaloids in mainstream and sidestream tobacco smoke mation 1033 ... mouse lymphoma 153 ... mouse skin 1131 tumour (review) 979 ... rat liver focus (review) 979 Alkyl/allyl sulfides liver enzyme activity and 78 Asthma fruit processing enzymes and 8.III ... occu- Allergens glue and plastic 3.VIII ... test for rat urinary pational and ethanolamines 8.III ... occupational and proteins 3.XI ... threshold for airborne latex 4.II pectin 79 Allergy (see also Anaphylaxis) bovine serum albumin 4.III Atherosclerosis dietary fish oils and 663 ... malonaldehyde ... carmine 77 ... epoxypropane 3.IX ... herbal tea 6.1 formation and Probucol 841 . inhaled nicotine 8.IV ... latex and fruit 9/10.11 ... Atractyloside biochemistry and toxicology 335 latex rubber and children 3.X ... menthol testing 9/10.II Auraptene anticancer effects 9/10.III carcinogenic ... Nail varnish components 12.1V ... peanut dose protection 149 ... citrus fruits and anticarcinogenicity threshold 3.1] ... peppermint oil testing 9/101] ... 4.11] piperazine diacrylamide 3.VIII ... protease 6.1V ... Avocado osteoarthritis treatment 4.III sunscreens and photocontact 3.XII ... tin 12.III ... 2,2’-Azobis(2-amidinopropane)dihydrochloride dermatitis 2,4,6-tris(dimethylaminomethy])phenol 9/10.VI from 9/10.VI “Alta” depigmentation and 8.1V Aluminium low dose toxicity 6.III ... oral dose and biliary vy. urinary excretion 505 Amaranth immunosuppression and 3.1 Bacteria intestinal growth and tannic acid 1053 Ames Salmonella typhimurium benzaldehyde mutagenic in Baking mutagenicity effect on Agaricus bisporus extracts new strains 6.1V 315 Amino acids daily requirements 8.1 Balkan endemic nephropathy haematotoxicity and 245 Amino peptidase safety evaluation of enzyme from Asper- Beans see specific types gillus niger 781 Bee toxicity and biological properties of propolis 347 Anaphylaxis carboxymethylcellulose 79 ...carmine 149... Beef heterocyclic amines content after cooking by different curry and 8.II ... millet 3.1] ... pine nuts 4.III ... methods 279 rambutan 12.11 ‘Bee glue’ see Propolis Anethole taste loss 9/10. VIII Benchmark dose comparison with NOAEL for carbenda- Angiosarcoma vinyl! chloride and 12.III zim toxicity 37 Antibacterial agents acylamino acids and properties of Benzaldehyde mutagenic in new Ames Salmonella typhi- myristoyl-methionine 771 murium strains 6.1V Anticancer properties 4-methylsulfinylbutyl glucosinate 8.1 Benzene DNA binding 3.VII, 3.VIII ... multiple myeloma ... auraptene 9/10.III ... carotenoids 3.V ... curcumins and 151 18 Index of Subjects Benzola|pyrene fruit and vegetables protective effect Cardioprotection grape juice 4.III ... salicylates 77 against clastogenicity 637 Cardiovascular disease (see also Heart disease) methyl Betaine chloroform hepatotoxicity and 655 chloride 8.1] Beverages sucrose acetate isobutyrate (SAID) toxicity Cardiovascular system soya phytoestrogens 3.1] studies (1988) 81 3-Carene guinea pig responses to 6.III Bile acids colonic phase I and II xenobiotic metabolizing Carmine allergy 77 ... anaphylaxis 149 enzymes 601 B-Carotene modulation of sister-chromatid exchanges 897 Biphenyl genotoxicity 3.VI Carotenoids anticarcinogenic effects 3.V ... breast cancer Births ratio of male to female in industrialized countries and 3.V ... influence on cyclophosphamide and dioxi- 6.V dine clastogenic activities | Bis(2-ethylhexyl) phthalate perinatal toxicity 963 Cashew nuts pectin cross-sensitization with 9/10.1] Bisphenol A_ genotoxicity 3.XI oestrogenic activity Castor oil fatty acids polyglycerol polyricinoleate (PGPR) 6.111, 9/10.1V glyceran ester 719 Bitter gourd fruits effect on enzyme activity and carcino- Cataracts vitamin C and 78 gen activation 475 CCK-B/gastrin receptor ligand CI-988 gastric effects in Bladder tumours sodium ascorbate and 9/10.1 cynomolgus monkeys 61 Blood-brain barrier T-2 toxin permeability and monamine Cell cycle arrest fumonisin B, sphingolipid concentration oxidase activity 955 and cyclin dependent kinase 791 Blood pressure (see a/so Hypertension) weight loss and Cellulose triacetate prostate cancer and fibre manufacture reduction of sodium intake 6.11 3.VII Bone mass_ milk and young women 78 Children diet and cancer in adults 3.1II ... latex rubber Bovine serum albumin allergy 4.1II allergy 3.X ... peanut allergy persistence 8.II ... vehicle Brain methylmercury exposure 153 exhaust gases and cancer 6.V ... zinc and growth 3.V Breast cancer alcohol and 4.1 ... carotenoids and 3.V ... Chinese tea low cholesterol 149 dietary fat and 4.1 ... green tea and 8.II ... occupational p-Chlorobenzotrifluoride inhalation toxicity 3.XI xenoestrogens 9/10.VI ... smoking and 9/10.X Chloroform betaine and hepatotoxicity 655 Breast implants connective tissue disorders 3.XI f-Chioroprene vapour carcinogenicity 9/10.VI Brick tea concentration and safety evaluation of fluorine Chiorpropham toxicity and sea urchin embryos 9/10.V in Pu’er and Bianxiao types 1061 Cholesterol Chinese tea and low levels 149 ... field beans British Toxicology Society BTS report on in vitro toxi- and 3.111 ... full-fat rice bran and blood 9/10.III ... cology 153 psyllium-enriched cereals and blood 77 ... rhubarb stalk Broccoli 4-methylsulfinylbutyl glucosinate anticancer fibre and 3.111 ... soya milk and 3.1] properties 8.1 ... colorectal cancer and 12.11 Cholic acid modulation of xenobiotic metabolizing Brussels sprouts liver enzymes and 4.II enzymes 601 1,3-Butadiene mutagenicity in man 3.VIII Choline dimethylamine formation and diet 923 Butter oesophageal cancer and 9/10.1I Chromosomes aberrations and chronic feeding of MeIQ Butylated hydroxyanisole (BHA) forestomach carcinogeni- 467 acesulfame-K and damage 3.1 meiotic city 299 ... rat strain sensitivity to carcinogenicity 299 segregation and quercetin diet, Drosophila melanogaster tert-Butylhydroquinone distribution and excretion 907 585 toluene effects in print workers 6.III ... vitamin B,» and damage 9/10.III C1-988 CCK-B gastrin receptor ligand gastric effects in Ca** release pathway y-hexachlorocyclohexane apoptosis cynomolgus monkeys 61 induction and 513 Cigarettes (see also Smoking ... Tobacco) flavoured 9 Cadmium osteoporosis risk factor 9/10.V . phytase effect lO.1X lung carcinogenicity and filters 153 ... primary on accumulation 7 tobacco heating design 7.1, 169... in vitro toxicology of Caffeine Frog Embryo Teratogenesis Assay~ Xenopus mainstream smoke condensate 183... in vitro toxicology (FETAX) evaluation of developmental toxicity of 59! of mainstream whole smoke 183 ... smoke from new ... green tea and induction of hepatic phase Il enzymes type less mutagenic 6.V 617 ... SIDS (sudden infant death syndrome) 3.1 Clastogenicity carotenoids influence on cyclophosphamide Calcium colon cancer and drinking water 150 prostate and dioxidine | fruit and vegetables protective effect cancer and 4.1 ... release pathway, )-hexachlorocyclo- against cyclophosphamide and benzo[a]pyrene 637 hexane apoptosis induction and 513 Coffee gastrointestinal cancer 4.1 ... heart disease and 3.1 Cancer see Carcinogenicity ... Tumours Helicobacter pylori 150 modulation of metal- Capsaicinoids carcinogenicity and 1065 induced genotoxicity by Maillard reaction products Carbamates Propoxur carcinogenicity 1125 trom 543 Carbaryl immune system and 12.111 Colon cancer broccoli and 12.11 .. . diallyl components of Carbendazim toxicity comparison of NOAEL and bench- garlic and human cells 761 . drinking water calcium mark dose 37 130 iron and manganese superoxide dismutase Carbodiimide — sensitization 9/10. VIII (MnSOD) activity in 819 ... pinto beans and 3.III ... Carbofuran toxicity 6.11! squalene and 3.1\ Carbon disulfide occupational exposure 9 10.‘ Colophony fumes and respiratory effects 151 patch Carboxymethyleellulose anaphylaxis 79 testing control 12.111 Carcinogenicity auraptene protection 1!49 available Connective tissue breast implants and disorders 3.XI experimental testing models 997 butylated hydroxy- Cooking HCA content beef 279 ... pork 289 anisole (BHA) 299 capsaicinoids 1065 Cooking oils polyunsaturated fatty acids (PUFA) in 8.1 i - chloroprene 9/10.VI ... cigarettes and filters 153 Copper toxicity and taurine 239 fragrances 687 ... heterocyclic amines 879 nickel 9 Cosmetics formaldehyde in 3.XIl mineral oils and 10.VI photocopier toner 9/10.VIII piperony! arthritis 4.1\ skin irritancy testing in man 3.XII butoxide 9/10.1V ... propoxur 1125 review of short- Coumarin unscheduled DNA synthesis in liver slices 647 and intermediate-term testing 979, 997 Creatine supplements and kidney function 8.1] sucTOSe acetate isobutyrate (SAID) 111 Cruciferous vegetables induction of glutathione S-transfer- Carcinogens potency labelling 3.XII Thai \ egetables ase and quinone reductase by glucosinolate derivatives and activation of 475 65 Index of Subjects 19 Curcumins anticarcinogenic effects 3.V Enzymes Armillariella tabescens, aflatoxin B, detoxification Curry anaphylaxis and 8.II by 563 ... colonic phase I and II xenobiotic metabolizing Cyclin dependent kinase fumonisin B, sphingolipid con- 601 ... cytochrome P450 role in quinalphos toxicity of centration and cell cycle arrest 791 antioxidant 437 ... fruit processing and asthma 8.III ... Cyclohexylamine plasma SH group oxidation enhance- improved testing by detergents 9/10.VII ... induction by ment 755 glucosinolate derivatives 365 ... microsomes 4.IV ... Cyclophosphamide carotenoids influence on clastogenesis | screening for respiratory sensitization by detergent 80 ... fruit and vegetables protective effect against clasto- Epoxypropane allergy 3.1X genicity 637 Epoxy resin hardener allergy 9/10.VI Cynomolgus monkeys CCK-B/gastrin receptor ligand CI- Equol cytochrome P450 inhibition 375 988 gastric effects in 61 Erratum primarily tobacco heating cigarette (TOB-HT) Cystamine bislactamide allergy 9/10.VIII and chemical composition of mainstream smoke 7.1 Cytochrome P450 inhibition by isoflavonoids (genistein . . . Erythritol safety data review 1139 equol) 375 ... role in quinalphos toxicity of antioxidant Ethanolamines occupational asthma and 8.III enzymes 437 3-Ethyl-1-propanol toxicity 151 Cytokines type 2 induction and platinum salt exposure 199 Ethylenebis(dicarbamate) genotoxicity 3.VI Ethylene glycol monomethyl ether genotoxicity 4.II Ethylene glycol mono-n-butyl ether acute toxicity in guinea DDT isomers _ oestrogenic activity 150 pigs 825 Decamethylcyclopentasiloxane inhalation toxicity 9/10.VII Ethylene oxide airborne contact dermatitis 12.II] DEHP low toxicity in primates 8.III 2-Ethylhexanoic acid oral toxicity 9/10.VII ... subchronic Deoxycholic acid modulation of xenobiotic metabolizing oral toxicity 429 enzymes 601 2-Ethylhexanol inhalation study 8.III ... NOAEL (no- Depigmentation ‘‘alta” and 8.1V observed-adverse-effect level) 165 ... vapour inhalation Dermatitis airborne contact , ethylene oxide 12.III ... 2,2’- toxicity 165 azobis(2-amidinopropane)dihydrochloride 9/10.VI 5-Ethylidene-2-norborene genotoxicity potential 8.II] Desmutagenicity Lactobacillus acidophilus cultured milk EU/COLIPA Phototoxicity screen study 9/10.X and tauco 805 Eye Draize irritation test and surfactant formulations 209 Detergents improved testing of enzymes 9/10.VII . irritation tests for oil water emulsions 47 ... low Detoxification aflatoxin B,; by enzymes of Armillariella volume irritation test and surfactant formulations 209 tabescens 563 . in vitro irritation test 47 ... surfactant formulations Dially! sulfide/disulfide arylamine N-acetyltransferase ac- 209 ... wine and age-related macular degeneration 3.1] tivity in human colon cancer cells 761 Diet childhood and cancer in adults 3.III ... lung cancer and 3.VI ... oral cancer and 3.III Dietary fat breast cancer and 4.1 False positives local lymph node assay and predictive skin N,N-Diethylaniline genotoxicity 3.VI, 3. VIII sensitization tests 327 Diethylene glycol dimethyl ether toxicity 9/10. VII Fats (see also Lipids) mood changes and diet 3.IV ... N,N-Diethylethanolamine toxicity 9/10. VIII trans-unsaturated and heart disease 77 Diethylnitrosamine vitamin E and necrogenicity 929 Fatty acids (see also Polyunsaturated fatty acids Digestive tract cancer see Gastrointestinal cancer (PUFA)) long chain polyunsaturated and infant devel- Diisocyanates mutagenicity testing 6.1V opment 12.I ... trans-unsaturated and heart disease 77 Dimethylamine formation from amine precursors 923 Dimethyl mercury extreme human toxicity 9/10.VI Fertility acetochlor and 78 Dioxidine carotenoids influence on clastogenesis | Fibre laxatives flatulence and 3.III Dioxin cancer in Seveso 153 Field beans cholesterol and 3.III Diterpenoid glycosides biochemistry and toxicology 335 Fish stir frying and MelIQx bacterial mutagen 3.V 2,5-Di(tert-butyl)-1,4-hydroquinone nerve damage 3.X Fish oils dietary, atherosclerosis and 663 Dithiocarbamate accelerator residues risk assessment and Flatulence fibre laxatives and 3.III latex-based medical devices 849 Flavanols green tea and induction of hepatic phase II Divinylbenzene inhalation toxicity 151 enzymes 617 DNA §agaritine and binding 971 ... benzene binding 3.VII, Flavonoids oestrogenic activity and 9/10.III ... quinone 3.VIII ... breaking activity of hydroxyfuranones in soy reductase induction and 623 sauce 305 ... coumarin and unscheduled synthesis in Flavour and Extract Manufacturers Association (FEMA) liver slices 647 ... fragmentation and y-hexachlorocy- GRAS assessment of lactone flavour ingredients 249 clohexane 513 ... mammary gland bioassay of A(a)C Flavour use of lactones 250 adduct formation 1033 ... melanoidin modulation of Flavouring substances safety evaluation principles of 529 damage 543 ... single strand breaks and Thiram 155... Flaxseed anticarcinogenic activity 3.III] unscheduled synthesis in liver slices and cooked food Fluoride long-term exposure and spermatogenesis mor- mutagens 455 ... welders and damage 4.II phology 1117 ... occupational genotoxicity 79 Docosahexaenoic acid dose—response 3.1V Fluorine concentration and safety evaluation in Pu’er Dogs methyl bromide dietary study in 575 Brick tea and Bianxiao brick tea 1061 Draize eye test oil/water emulsions 47 surfactant Folate heart disease and 3.V formulations 209 Folic acid lower homocysteine blood levels 6.11 Drinking water (see a/so Water) nitrate and cancer 4.11... Food colour UV irradiation decomposition and mutageni- spontaneous abortion and quality 6.V city 811 Drosophila melanogaster meiotic chromosome segregation Forestomach butylated hydroxyanisole (BHA) carcino- and quercetin diet 585 genicity 299 Formaldehyde cosmetics with 3.XII Fragrances respiratory effects 9/10.VIII ... SAR analyses ECVAM Task Force | skin irritation tests proposals 8.1V and potential carcinogenicity 687 Elderly heart disease 150 Freeze-drying mutagenicity effect on Agaricus bisporus Emulsions eye irritation tests for oil/water 47 extracts 315 20 Index of Subjects Frog Embryo Teratogenesis Assay—Xenopus (FETAX) Hepatic enzymes Brussels sprouts 4.I] phase II, evaluation of developmental toxicity of caffeine and flavanols and green tea 617 metabolites 591 Hepatobiliary system sucrose acetate isobutyrate (SAID) Fructose prostate cancer and 4.1 and human function 141 Fruit citrus, Auraptene and anticarcinogenicity 4.III ... Hepatotoxicity 2-nitropropane and green tea protective processing enzymes and asthma 8.III ... protective effect effects 1043 chloroform and betaine 655 against cyclophosphamide and benzo[a]pyrene clasto- microsomal enzyme induction and 831 genicity 637 Herbal tea allergy 6.II Fumonisin B, developmental toxicity and pregnancy 673 Heterocyclic amines content in beef cooked by different inhibition of sphingolipid biosynthesis 497 methods 279 ... formation, occurrence, intake and pregnancy and 397 ... sphingolipid concentration, cyclin carcinogenicity review 879 ... gravy content and meat dependent kinase and cell cycle arrest 791 drippings 279 ... mammary gland bioassays and A(a)C 1033 Hexachlorobenzene occupational toxicity 6.II] Garlic attenuation of iron-nitrilotriacetate (Fe-NTA)- y-Hexachlorocyclohexane apoptosis induction and intra- mediated renal oxidative stress 485 ... diallyl compo- cellular Ca** release pathway 513 ... DNA fragmenta- nents and human colon cancer cells 761 ... hypertension tion and 513 and 77 ... lipid-lowering effects 9/10.II Hexamethylphosphoramide oral toxicity 151 Gastrointestinal cancer (see a/so Colon cancer) aspirin and Homocysteine folic acid and vitamin B,> lower blood levels 6.11 6.V ... tea/coffee and 4.1 Genistein cytochrome P450 inhibition 375 a-Hop acids subchronic toxicity in dogs 915 Genotoxicity biphenyl 3.VI ... bisphenol A 3.XI ... bone Human immunodeficiency virus (HIV) Lactobacillus reuteri marrow, sennosides 937 ... N,N-diethylaniline 3.VIII ... supplement safety and tolerance 1085 Ethylenebis(dicarbamate) 3.VI ... ethylene glycol mono- Hydroquinones dermal cream application and toxicity 609 methyl ether 4.II ... 5-ethylidene-2-norborene 8.III ... ... genotoxicity 3.XI ... nephrotoxicity and 609 fluoride 79 ... glyphosate 12.III ... hydroquinones 3.X]I p-Hydroxybenzoic acid oestrogenicity 3.1 . isopropylammonium glyphosate 3.VII ... lignans, Hydroxyfuranones DNA breaking activity in soy sauce plant 6.1V ... lipids peroxidation 9/10.III ... modulation 305 of metal-induced by Maillard reaction products from Hypertension (see also Blood pressure) garlic and 77 ... coffee 543 ... nitroanilines 3.1X ... nitrobenzene 3.1X ... linseed oil and 77 ... salt intake and 8.1 ... sugar intake organophosphate 3.VI ... printing inks and pigments and 4.111 8.11 ... propyl gallate 3.1 ... pyrethroids 3.VII ... rimsulfron 12.111... roundup 3.VII ... safrole 3.1V ... soy sauce 9/10.IV ... sucrose acetate isobutyrate (SAID) IgA monoclonal antibodies =vomitoxin-induced and nephro- lack of 127 ... 1,2,3,4-tetrahydronaphthalene-|-hydro- pathy 1095 peroxide 9/10.VII ... titanium oxide after irradiation Immunoaffinity column-linked HPLC ochratoxin A tox- 152 ... triazine 8.1! ... trimethylbenzenes 8.III ... icity 445 vinclozolin’ 12.111 Immunoassay ochratoxin A toxicity 445 Gestation simmondsin or defatted jojoba meal effects on Immunosuppression amaranth and 3.1... tartrazine and 3.1 rat 13 Immunotoxicity patulin and 1107 Ginseng anticancer effects 9/10.1V Indian smoking products alkaloids in tobacco smoke 1131 Glucobrassicins indole-3-carbinol prevention of cyclopho- Indigo carmine UV irradiation and mutagenicity 12.1 samide-induced micronucleus formation 975 Indole-3-carbinol prevention of cyclophosamide-induced Glucosinolate enzymes induction by derivatives of 365 micronucleus formation 975 Glucuronosyl transferases green tea and 617 Insulin resistance and vitamin D deficiency 6.1 ... trichlor- Glutathione S-transferase green tea and 617 ... induction oethylene and 4.1] by glucosinolate derivatives from cruciferous vegetables Interleukin-1/ == vomitoxin modulation of secretion 409 365 ... Thai vegetables effect on activity 475 Interleukin-6 vomitoxin modulation of secretion 409 Glyceran esters polyglycerol polyricinoleate (PGPR) and Intestine (see also Colon cancer Gastrointestinal castor oil fatty acids 719 ... safety assessment and cancer) bacterial growth and tannic acid 1053 ingestion 719 Iran EU ban on pistachio nuts 3.II Glycoalkaloids toxicology 383 Iron manganese superoxide dismutase (MnSOD) activity Glyphosate genotoxicity 12.III] and colon cancer 819 Grape juice cardioprotection and 4.11] lron-nitrilotriacetate (Fe-NTA) garlic oil attenuation of GRAS (Generally Recognized as Safe) FEMA assessment oxidative renal stress 485 of lactone flavour ingredients 249 Irradiation titanium oxide and genotoxicity 152 Gravy HCA content and meat drippings 279 Irritants air fresheners 8.1V Green tea anticarcinogen effects 3.VI ... anti-genotoxicity Ischaemic heart disease (see also Heart disease) whole 78 ... breast cancer and 8.II ... caffeine and flavanols grains and 12.1] induction of hepatic phase II enzymes 617 ... hepato- Isoflavonoids cytochrome P450 inhibition 375 toxicity protective effects and 2-nitropropane 1043 Isohumulones subchronic toxicity in dogs 915 Guar gum partially hydrolysed subchronic toxicity 3.II Isopropylammonium glyphosate genotoxicity 3.VII Guinea pigs ethylene glycol mono-n-butyl ether acute toxicity in 825 Jet fuel lung toxicity 9/10.VII Jojoba defatted meal effects on rat gestation 13 Haematotoxicity Balkan endemic nephropathy and 245 Headaches triethylamine and 3.1X Heart disease coffee and 3.1 ... elderly 150 ... folate and Kidney cancer vegetables and 9/10.III vitamin Bs 3.V ... ischaemic, whole grains and 12.11... Kidneys (see a/so Renal stress) creatine supplements and passive and active smoking 3.XI ... trans-unsaturated 8.11... oral dose aluminium and urinary excretion 505 fats 77 ... turmeric 4.11] Kojic acid oral administration and thyroid tumour induc- Helicobacter pylori alcohol, coffee 150 tion 697 Index of Subjects Konjac flour sensitization 3.V 4-Methylsulfinylbutyl glucosinate anticancer properties in broccoli 8.1 Methylxanthines developmental toxicity 591 Lactic acid bacteria see Lactobacillus sp. Microcystin fatal poisoning 9/10.VIII Lactobacillus acidophilus desmutagenicity of cultured milk Micronuclei Thiram mutagenicity 155 and tauco 805 Microsomes enzyme induction and hepatotoxicity 831... Lactobacillus reuteri supplement safety and tolerance and in vitro solvents and enzymes 4.I'V potential HIV infections 1085 Milk bone mass and young women 78 Lactobacillus rhamnosus aflatoxin B, binding by 321 Millet anaphylaxis 3.1] Lactones_ chemical identity 250 ... FEMA GRAS assess- Monamine oxidase T-2 toxin blood-brain barrier per- ment of flavour ingredients 249 ... flavour use 250 ... meability and activity 955 metabolism 251 ... toxicology 255 Monascus_ anti-mutagenicity of pigments 77 Latex allergy and fruit 9/10.II ... allergy in children 3.X Monoethanolamine reproductive toxicity 152 ... glove quality control 3.X ... medical devices and Monooxygenases_ Thai vegetables effect on activity 475 dithiocarbamate accelerator residues risk assessment 849 Mood changes _ low fat diet and 3.1V . non-allergenic respiratory problems 3.XI ... rate of Mortality statistics Albania adult rates 3.1V sensitization to 6.III ... threshold for airborne allergens Mouse hairless model for chronic toxicity of topical 4.1] chemicals 867 Laxatives, fibre flatulence and 3.III Mouse skin tumour assay review 979 LDgpo tests 3. XIII Multiple myeloma benzene and 151 Lead phytase effect on accumulation 7 Mushrooms see specific types Lignan genotoxicity of plant 6.1V Mutagenicity aspartame 12.1 ... baking effect on Agaricus Linoleic acid conjugated toxicity 391 bisporus extracts 315 ... benzaldehyde in new Ames Linseed oil hypertension and 77 Salmonella typhimurium strains 6.1V ... 1,3-butadiene Lipids (see also Fats) fat intake and serum 3.IV ... 3.VIII ... cooking oils and fumes 12.11 ... diisocyanates, peroxidation and genotoxicity 9/10.1I] testing 6.1V ... indigo carmine 12.1... terpineol 12.1... Lithium skin disease and consumption 152 tetravinyl-tetramethylcyclotetrasiloxane 3.XII ... thiram Lithocolic acid modulation of xenobiotic metabolizing (tetramethylthiuram disulfide) and testing in mice 155... enzymes 601 UV irradiation decomposition of food colours 811 Liver (see also Hepatic enzymes) Brussels sprouts and Mutagens PBTA-1 80... and unscheduled DNA synthesis enzymes of 4.II cooked food mutagens and in liver slices 455 unscheduled DNA synthesis in slices 455 ... enzyme Mycotoxins (see also specific types) fumonisin B, and activity and alkyl/allyl sulfides 78 oral dose pregnancy 397 aluminium and excretion 505 Myristoyl-methionine antibacterial properties of acyl- Low volume eye test oil/water emulsions 47 amino acids 771 Lung carcinogenicity and cigarette filters 153 Lung cancer diet and 3.VI ... lycopene and 78 ... metal workers risk 12.II] ... theaflavins 3.VI Nail varnish components allergy 12.1V Lycopene lung cancer and 78 Nephropathy Balkan endemic 245 ... vomitoxin-induced Lymphoma mouse assays 153 IgA Mabs and 1095 Nephrotoxicity hydroquinones cream application and tox- icity 609 Maillard reaction modulation of metal-induced genotoxi- Nerves 2,5-di(tert-butyl)-1,4-hydroquinone damage 3.X city by products from coffee 543 Nickel occupational carcinogenicity 9/10.VI Malonaldehyde formation and probucol 841 Nicotine allergy to inhaled 8.1V Maltitol anticancer activity 8.1 Nitrate drinking water and cancer 4.II Mammary gland bioassay A(x)C and DNA adduct for- Nitroanilines genotoxicity 3.1X mation DNA 1033 Nitrobenzene genotoxicity 3.1X Manganese superoxide dismutase (MnSOD) iron and 2-Nitropropane green tea hepatotoxicity protective effects activity in colon cancer 819 and 1043 Meat diet, cancer and genetics 12.II N-Nitroso-N-(3-keto-1,2-butanediol)-3'-nitrotyramine tu- Medical devices dithiocarbamate accelerator residues risk mour promoter effect 631 assessment and latex-based 849 NOAEL (no-observed-adverse-effect level) antimony in Meiotic chromosome segregation in Drosophila melanoga- drinking water 21 ... comparison with benchmark dose ster On quercetin diet 585 for carbendazim toxicity 37 ... sucrose acetate isobuty- MeIQ (2-amino 3,4-dimethylimidazo[4,5-/ |])quinoline —chro- rate (SAID) 121 mosome aberrations and chronic feeding 467 ... human p-Nonylphenol oral toxicity 151 metabolism of 6.II ... stir frying fish and mutagen 3.V Nostoc flagelliforme safety evaluation as potential food Melanoidin modulation of DNA damage 543 1073 Melatonin contaminants in commercial preparations of Nutrients supplements potentially harmful 9/10.11] 6.11 Nutrition implications of macronutrient substitutes con- Menhaden oil steatosis and 555 ference report 145 Menstrual cycle PCB exposure and 3.VI Nuts (see also Peanut) cashew, pectin cross-sensitization Menthol allergy testing 9/10.II with 9/10.1I ... pine, anaphylaxis 4.III ... pistachio , EU Metals Maillard reaction products from coffee modulate ban on Iranian 3.1] induced-genotoxicity 543 Methoxychlor reproductive toxicity 150 3-Methyl-1-butanol toxicity 151 Occupational asthma ethanolamines 8.III ... pectin 79 Methyl bromide dietary study in dogs 575 ... and oral Occupational carcinogenicity nickel 9/10. VI teratogenicity 421 ... subchronic toxicity 9/10.1V Occupational exposure carbon disulfide 9/10.V Methyl chloride cardiovascular disease and 8.II Occupational exposure limits 12.111], 12.1V N-Methyl ethanolamine _ sensitising potential 6.1V Occupational toxicity genotoxicity of fluoride 79 Methylmercury maternal exposure and brain function 153 hexachlorobenzene 6.111 22 Index of Subjects Ochratoxin A human toxicity study in Tokyo 445 ... human toxicology studies 743 ... preparation, use and immunoassay and immunoaffinity column-linked HPLC biological properties 711 ... safety assessment 711 445 Polyoxyethylene surfactants instability 9/10.X Oesophageal cancer butter and 9/10.1I ... metalworking Polystyrene skin reactions 3.XII fluids and 9/10.VI Polyunsaturated fatty acids (PUFA) cooking oils and 8.1 Oestrogenic activity phthalates 79 ... p-Hydroxybenzoic ... long chain and infant development 12.1 ... n-3 , diet acid 3.1 and atherosclerosis 663 Oestrogens (see also Phytoestrogens) bisphenol A and Polyvinyl chloride (PVC) exposure and testicular cancer activity 6.1II ... DDT isomers and activity 150 ... 3.VII ... skin absorption of di(2-ethylhexyl)phthalate environment and 4.II ... flavanoids and activity 9/10.III from film 521 . occupational xenoestrogens and breast cancer 9/ Pork heterocyclic amines content after cooking by differ- 10.VI ... screening test reliability 9/10.1II ent methods 289 Oils cooking and fumes mutagenicity 12.I] ... hydrogen- Post-menopausal hot flushes soya supplements and 4.III ated vegetable, and stroke 9/10.II Potassium iodide salivary gland cancer 6.1V Olestra low-dose gastrointestinal effects 149 Pregnancy developmental toxicity and fumonisin B, 673 Oleth-3-phosphate sensitization 80 . fumonisin B,; and 397 ... outcome after male Oleth-5-phosphate sensitization 80 pesticide exposure 3.VII Olive oil anticancer properties 8.II Primarily tobacco heating cigarette (TOB-HT) and chemi- Oral cancer diet and 3.III ... smokeless tobacco and 1015 cal composition of mainstream smoke 7.I (Erratum), 169 Oral LDsp Test validation of alternatives 12.I1V Printing inks genotoxicity of pigments 8.III Oral toxicity 2-ethylhexanoic acid and subchronic 429 Print workers chromosome effects and toluene 6.III Organophosphate genotoxicity 3.VI Probiotics Lactobacillus reuteri supplements and HIV 1085 Osteoarthritis avocado/soybean treatment 4.III Probucol blood plasma oxidation 841 ... malonaldehyde Osteoporosis cadmium risk factor 9/10.V formation and 841 Propolis toxicity and biological properties 347 Propoxur carcinogenicity 1125 p53 protein vinyl chloride exposure and mutant 6.III Propyl gallate genotoxicity 3.1 Paraffin long-term feeding of liquid 3.X Prostate cancer calcium, fructose and vitamin D 4.I ... Paraquat respiratory tract and 3.VI cellulose triacetate fibre manufacture 3.VII ... selenium Patulin immunotoxicity and 1107 and 12.1] ... vitamin E supplements 6.1 PBTA-1 new mutagen 80 Protease allergy 6.1V PCBs see Polychlorinated biphenyls (PCBs) Psyllium enriched cereals and blood cholesterol 77 Peanut allergy and dose threshold 3.1] ... allergy persist- PVC see Polyvinyl chloride (PVC) ence in children 8.1] Pyrethroids genotoxicity 3.VII Pectin cross-sensitization with cashew nuts 9/10.II ... occupational asthma and 79 Pectinesterase safety of 12.1 Quercetin meiotic chromosome segregation in Drosophilia Peppermint oil allergy testing 9/10.II melanogaster 585 Pesticides pregnancy outcome after male exposure 3.VII Quinalphos cytochrome P450 role in toxicity of antiox- . regulatory testing and second species choice 9/10.V idant enzymes 437 . Sheep reproductive hormones and 9/10.IV Quinone reductase flavonoids and induction 623 Petrochemicals abortion and 3.VIII induction by glucosinolate derivatives from cruciferous Petrol multiple chemical sensitivity 9/10. VII vegetables 365 Pharmaceutical coatings Aquacoat" ECD ethyl cellulose aqueous dispersion toxicity and 705 Pharmacokinetics sucrose acetate isobutyrate (SAID) 95 . Sucrose octaisobutyrate (SOIB) 95 Rambutan anaphylaxis 12.II Phenylalanine daily requirements 8.1 Rat liver focus assay (review) 979 o-Phenyl phenol genotoxicity 3.VI Rats strain sensitivity to BHA carcinogenicity 299 Phosphine inhalation toxicity 9/10.V Rat urinary proteins allergens test 3.XI Photocopier toner lung carcinogenicity 9/10.VIII Reactive oxygen species shark-cartilage containing prep- Phototoxicity screen EU/COLIPA study 9/10.X aration scavenger activity 1079 di(2-ethythexy!)Phthalate percutaneous absorption from Rectal cancer broccoli and 12.1] PVC film 521 Renal stress garlic oil attenuation of iron-nitrilotriacetate Phthalates estrogenic activity 79 (Fe-NTA)-mediated oxidative 485 Phytase effect on zinc bioavailability and cadmium and Reproduction acrylic acid and 152 ... simmondsin or lead accumulation in rats 7 ... sensitization 79 defatted jojoba meal effects on rat gestation 13 ... Phytoestrogens (see also Odcstrogens) benefits 8.1 sucrose acetate isobutyrate (SAID) and 135 cardiovascular system and soya 3.11 ... resveratrol 3.1] Respiratory diseases acrylates 3.1X ... triphenylmethane Phytosterols lipid metabolism and 9/10.1 triisocyanate and 151 Pigments anti-mutagenicity of Monascus 77 ... printing Resveratrol phytoestrogen 3.1 inks and genotoxicity of 8.III Retinal modulation of sister-chromatid exchanges 897 Pine nuts anaphylaxis 4.IIl Retinol skin cancer suppression 150 Pinto beams colon cancer and 3.III Rhubarb cholesterol and stalk fibre 3.11] Piperazine diacrylamide allergy 3.VIII Riboflavin modulation of sister-chromatid exchanges 897 Piperonyl butoxide carcinogenicity 9/10.1V Rice full-fat bran and blood cholesterol 9/10.III Pistachio nuts EU ban on Iranian 3.1 Rimsulfron genotoxicity 12.11] Platinum type 2 cytokines induction and salt exposure 199 Roundup genotoxicity 3. VII Polychlorinated biphenyls (PCBs) exposure and menstrual Rubber latex see Latex cycle 3.V1... fish contamination and mink reproduction 9 10.1V Polyglycerol polyricinoleate (PGPR) carcinogenic poten- tial 747 digestion, metabolism and excretion 719 ... Saccharin long-term study in monkeys 6.I

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Food and Chemical Toxicology 1998: Vol 36 Index PDF

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Preview Food and Chemical Toxicology 1998: Vol 36 Index

PII: S0278-6915(99)00095-2 Index of Authors Abel S., 497 Chiang M., 141 Gembardt C., 165 Adams T. B., 249 Chiarello P. G., 929 Gerberick G. F., 327 Agrawal R. C., 975 Chipman J. K., 375 German J. B., 585 Ahokas J., 321 Chou M. W., 1053 Gescher A., 375 Ahr H. J., 979, 997 Chu I., 21 Gettings S. D., 47, 209 Akagi A., 1065 Chung H. L., 169 Gil-Martin E., 941 Amacher D. E., 831 Chung J. G., 761 Gingell R., 825 Andreoli C., 155 Chung K.-T., 1053 Gordon D. R., 429 Arcadi F. A., 963 Ciacci-Zanella J. R., 791 Gott D., 849 Arnold D. L., 771 Cifone M. A., 127 Grasso P., 1015 Ataya D. G., 1085 Clifford M. N., 617 Gray K., 14] Athar M., 485 Coenen T. M. M., 781 Greer D. B., 249 Attias L., 37 Cokelaere M., 13 Greger J. L., 505 Aughton P., 781 Collins H. E., 585 Gu L.-Q., 563 Avalos J. T., 183 Collins T. F. X., 397, 673, 1117 Guest D., 521 Ayres P. H., 191 Costa C., 963 Gupta S., 21 Costa G., 963 Guseva N. V., 1 Bach P. H., 335 Crebelli R., 155 Baijal P. K., 601 Hager M., 637 Bagar S. M., 1125 Daenens P., 13 Hagiwara A., 299 Bar E. A., 1139 Das M., 437 Hall R., 529 Barratt M. D., 233 David R. M., 429, 609 Hall R. L., 111 Barton P. T., 455, 647 Day A. J., 623 Hall-Manning T. J., 233 Basketter D. A., 199, 233, 327 De B., 937 Hansen D. K., 397, 673 Beamand J. A., 455, 647 Dearman R. J., 199 Hasegawa R., 1043 Bernard L. G., 429 Deckardt K., 165 Hawley R. S., 585 Bernardo-Filho M., 1079 Decuypere E., 13 Hayward S., 771 Bernt W. O., 1139 Deisinger P. J., 521 Helsby N. A., 375 Bestervelt L. L., 61 Delzenne N. M., 555 Henwood S. M., 135 Bird R. P., 601 Dethloff L. A., 61 Hepburn P. A., 747 Black T., 1117 Doolittle D. J., 183, 191 Hernaux N. A., 555 Black T. N., 397, 673 Doull J., 249 Hildebrand B., 165 Blair M., 121 Drugarin D., 245 Hines J., 233 Blankemeyer J. T., 383 Dunkelberg H., 897 Hintze K. L., 47, 209 Blonk C. G., 663 Durnev A. D., 1 Hiramoto K., 305 Boatman R. J., 825 Dutta A., 937 Hirose M., 299 Bodnar J. A., 169 Dwivedi P. D., 437 Hofmann P., 637 Hojo H., 421 Bolte H. F., 575 Bombick D. W., 183, 191 Edenharder R., 637, 897 Holland G. H., 233 Bomhard E., 979, 997 El-Nezami H., 321 Hori M., 1073 Bootman J., 849 English J. C., 609 Hosono A., 805 Borgerding M. F., 169 Enzmann H., 979, 997 Howard P. C., 397, 673 Borzelleca J. F., 1139 Eppley R. M., 397, 673 Howes D., 711, 719 Boysen B. G., 111, 135 Hsieh C. L., 761 Brooks K., 409 Faulkner B. C., 591 Hu M.-L., 755 Brown E. D., 279, 289 Feder P. I., 47, 209 Huang H.-P., 631 Brown R. D., 1107 Felton J. S., 279, 289 Hwang D. F., 239 Brunnemann K. D., 997 Felzenszwalb I., 1079 Bryant M. A., 397, 673 Fernandez-Briera A., 941 latropoulos M., 979, 997 Bu-Abbas A., 617 Field W. E., 111 Iglesias A. C., 929 Burdock G. A., 347 Fitzpatrick D. W., 601, 947, 955 Ikeda G. J., 907 Burkhardt J. E., 831 Flamm G., 1139 Imperatore C., 963 Butterworth L. F., 1107 Flo G., 13 Inoue R., 467 Ford R. A., 249 Inoue T., 1043 Caldeira-de-Araujo A., 1079 Fort D. J., 591 Ioannides C., 315, 617 Calvo P., 941 Foster W., 21 Iqbal M., 485 Frangart J., 637 Ito A., 697 Cao J., 1061 Carere A., 155 Freeman C., 705 Itoh N., 811 Chagnon M., 915 Friedman M., 383 Ivett J. L., 127 Chang W.-C., 631 Fujimoto N., 697 Izumi K., 1065 Chappel C. I., 81, 101, 111, 121, 135, Fujita H., 467 141, 915 Furusawa N., 811 Jagerstad M. I., 879 Chen G. W., 761 Furuya M., 445 James C. T., 719 Chen I. L., 513 Jeffery E. H., 365 Cheng H. M., 239 Garleb K. A., 1085 Johansson M. A. E., 879 Cheng W.-Q., 563 Gelderblom W. C. A., 497 Jones C., 791 13 14 Index of Authors Jordao Jr A. A., 929 McGuire P. F., 771 Rogers J. C., 169 Juberg D. R., 429 McWilliams M. L., 383 Rorie J., 1117 Mehrotra N. K., 1125 Rorie J. I., 397, 673 Kai S., 1043 Meijer G. W., 663 Rosenkranz H. S., 687 Kaneda M., 421 Merrill Jr A. H., 791 Ross I. A., 907 Kang J. J., 513 Miller D., 771 Rossi S., 279 Kankaanpaa P., 321 Minami T., 1065 Rothman N., 279, 289 Kato T., 305 Mitchell S. C., 923 Roy G., 697 Katz G. V., 429 Miyake T., 841 Ruggles D. I., 397, 673 Kawamura O., 445 Modderman J., 1139 Rumbeiha W. K., 1095 Kennepohl E., 1139 Moreno F., 929 Kerkhoff G., 897 Morgan W. T., 183 Sadrieh N., 1033 Kerr D., 375 Morinaga T., 1073 Saha A., 73, 937 Khanna S. K., 437 Morrison C. C., 169 Sai K., 1043 Kikugawa K., 305 Most E., 7 Sakaki S., 1073 Kim S. K., 655 Moyer C., 609 Salemi M., 963 Kim Y. C., 655, 655 Mukherjee A., 73, 937 Salminen S., 321 Kimber I., 199, 327 Mukhopadhyay M. J., 73, 937 Salmon C. P., 279, 289 King R. S., 1033 Munro I. C., 249, 529, 1139 Sano N., 1065 Kingston S., 365 Munson A. E., 1107 Sapienza P. P., 907 Kitano M., 811 Murli H., 183 Schardein J. L., 135 Kitts D. D., 543 Murray F. J., 591 Schlatter C., 971 Kligman A. M., 867 Musgrove D. L., 1107 Schlueter G., 979, 997 Kligman L. H., 867 Myhr B. C., 127 Schneider F., 245 Klimisch H.-J., 165 Schomaker S. J., 831 Klopman G., 687 Nagao M., 467 Schramm D. D., 585 Knize M. G., 279, 289 Nakatani T., 697 Schut H. A. J., 1033 van de Kooi A. J., 663 Newberne P., 249 Scimeca J. A., 391 Kotkoskie L. A., 705 Newton P. E., 575 Seki H., 1073 Kiihn E., 13 Nishimori T., 1073 Seredenin S. B., | Kumar S., 975 Shackelford M. E., 397, 673 Kuratko C. N., 819 O’Donoghue J. L., 609 Shephard G. S., 497 Kuroda K., 811 Obatomi D. K., 335 Shephard S. E., 971 Kurokawa Y., 1043 Olejnik N., 397, 673, 1117 Shibamoto T., 841 Kusamran W. R., 475 Oreshchenko A. V., 1 Shirai T., 299 Otsuka H., 1065 Shubik P., 529 Laborde J. B., 397 Ozaki A., 811 Shukla Y., 1125 Laborde J. B., 673 Simmons D. F., 169 Lake B. G., 455, 647 Pacchierotti F., 155 Sinha R., 279, 289 Lawlor T. E., 127 Pakhale S. S., 1131 Skog K. I., 879 Lecavalier P., 21 Pallauf J., 7 Smith M., 739, 743 Lee M.-J., 631 Palmer T. E., 135 Smith M. R., 747 Levander O. A., 279, 289 Paquet A., 771 Smith R. L., 249, 923 Lewis S., 825 Patmore S. J., 61 Smith S. Y., 915 Li X., 305 Paunescu V., 245 Snyderwine E. G., 1033 Liang R., 563 Pelielo de Mattos J. C., 1079 Snyman §S. D., 497 Lin J., 445 Perry L. G., 521 Sprando R. L., 397, 673, 1117 Lin J. G., 761 Pestka J. J., 409, 1095 Staack R., 365 Lin W.-L., 631 Poon R., 21 Stanescu D. I., 245 Lin Y.-L., 631 Portoghese P. S., 249 Stazi A. V., 37 Liu D.-L., 563 Price R. J., 455, 647 Stover E. L., 591 Liu J. W., 1061 Procter B. G., 101 Suber R. L., 575 Llewellyn G. C., 1107 Propst T. L., 591 Sugiura Y., 445 Lordo R. A., 47, 209 Putnam K., 191 Sutherland J. E., 505 Lu Z., 1053 Putnam K. P., 183 Swanevelder S., 497 Lynch B. S., 1139 Swanson C, A., 279 Rahi M., 575 Ma L., 563 Ramsey M. J., 467 Takenaka H., 1073 MacKenzie K. M., 111, 135 Rapisarda A., 963 Tamano §S., 299 Macri C., 37 Ratanavila A., 475 Tanaka H., 299 Maita K., 421 Rauscher R., 637 Tanaka N., 1073 Maki S., 445 Rayburn J. R., 383 Tanimura A., 1043 Malcolm S., 771 Reed Bombick B., 183, 191 Taper H. S., 555 Mangan P. P., 169 Rennie G., 233 Tatu C. A., 245 Mann A. H., 1015 Report M., 145 Tepsuwan A., 475 Mantovani A., 37 Revell P., 233 Teramoto S., 421 Maranghi F., 37 Reynolds R. C., 81, 95 Thomas B., 2! Marchese A., 963 Rhodes D., 279, 289 Tierney B. M.., 61 Marin-Martinez M. L., 409 Rhodes M. J. C., 623 Timmer W. G., 663 Maru G. B., 1131 Ricciardi C., 37 Tinkler J., 849 Masuda T., 811 Rimbach G., 7 Tisdel P. J., 111, 135 Matsushima T., 467 Risner C. H., 169 Tjurina L. S., |! McCay J. A., 1107 Ritskes-Hoitinga J., 663 Topping D. C., 429 Index of Authors Totman L. C., 609 Wagner B. M., 249 Wilson R., 711, 719, 739, 743, 747 Tredger J. M., 455 Walker R., 315, 617 Wingate D. E., 169 Trimarchi G. R., 963 Wallig M. A., 365 Winkler L. S., 169 Trucksess M. W., 397, 673 Walter A., 7 Wolf B. W., 1085 Tsai H.-H., 755 Walton K., 315 Wong S.-S., 409 Tsuchida M., 1073 Wang C.-J., 631 Woods L. A., 249 Tucker J. D., 467 Wang E., 791 Wang J., 947, 955 Yamada A., 1073 —_ Wang L. C., 239 Yamaguchi H., 811 nage ag re Watanabe H., 697 Yamaguchi Y., 1073 eno Y., 445 Uhrig M. S.. 169 Watarai K., 1073 Yan D., 1095 Weil C. S., 249 Yannai S., 623 Umemura T., 1043 a Weissenberg M., 383 Yao D.-S., 563 Ve, TS Wendelboe F. N., 169 Yen-Yang H. F., 513 West A. J., 135 Yoshida M., 305 Valli V. E., 21 van der Westhuizen L., 497 Young R. R., 127 Van Boven M.., 13 Weststrate J. A., 663 Van Schie B. J., 711 Wheeler K. B., 1085 Zandee J. C., 61 Vannucchi H., 929 White Jr K. L., 1107 Zapponi G. A., 37 Vermaut S., 13 Wiersma A., 663 Zhang A. Q., 923 Verschuren P. M., 663 Wijewickreme A. N., 543 Zhang Y. P., 687 Villani P., 155 Williams G. M., 979, 997 Zhao Y., 1061 Vlaovic M. S., 429 Williamson G., 623 Zhou H.-R., 409 Volgareva G. M., | Wilson J. R., 947, 955 Zijno A., 155 Vollmuth T. A., 591 Wilson N. H., 575 Zucoloto S., 929 PII: S0278-6915(99)00083-6 Index of Subjects A(a)C (2-Amino-9H-pyrido-[2,3-bjindole) DNA adduct 3.V ... flaxseed 3.1II ... ginseng 9/10.IV ... green tea formation and mammary gland bioassay 1033 3.VI ... maltitol 8.1 ... olive oil 8.1] Abortion petrochemicals and 3.VIII ... spontaneous and Antimony NOAEL (no-observed-adverse-effect level) in drinking water quality 6.V drinking water 21 ... subchronic toxicity in drinking Acesulfame-K chromosome damage and 3.1 water in rats 21 ... toxicity 3.X Acetochlor fertility and 78 Antimutagenicity Monascus pigments 77 Acrylates respiratory diseases 3.1X Apoptosis y-hexachlorocyclohexane induction and intra- Acrylic acid reproduction and 152 cellular Ca?* release pathway 513 Acylamino acids antibacterial agents properties of myris- Aquacoat" ECD ethyl cellulose toxicity and aequous toyl-methionine 771 dispersion 705 ADMUL WOL see Polyglycerol polyricinoleate (PGPR) Armillariella tabescens aflatoxin B, detoxification by Aflatoxin B, binding by Lactobacillus rhamnosus 321 ... enzymes of 563 detoxification by Armillariella tabescens enzymes 563 Aroclor 1254 Rhesus offspring sex ratios 451 Agaricus bisporus extract mutagenicity after baking/freeze- Arsenic stroke and 79 drying 315 Artherosclerosis n-3 polyunsaturated fatty acids (PUFA) Agaritine DNA binding 971 and diet 663 Air fresheners irritants 8.1V Arthritis avocado, treatment 4.III ... cosmetic mineral oils and 4.1V Air pollution new mutagen 3.XI Arylamine N-acetyltransferase activity in human colon Albania adult mortality rates 3.1V cancer cells and diallyl disulfide 761 Albumin bovine serum, allergy 4.III Asbestos environmental exposure and cancer 3.IX ... non- Alcoholization free-choice drinking water ingestion in rats occupational risks 9/10.1X 941 Aspartame mutagenicity 12.1 Alcohol breast cancer and 4.1 ... heaith benefits 149 ... Aspergillus niger safety evaluation of amino peptidase Helicobacter pylori 150 from 781... safety testing of aminopeptidase 12.1 Algae Nostoc flagelliforme safety evaluation as potential Aspirin digestive tract cancer 6.V food 1073 Assays mammary gland and A(a)C DNA adduct for- Alkaloids in mainstream and sidestream tobacco smoke mation 1033 ... mouse lymphoma 153 ... mouse skin 1131 tumour (review) 979 ... rat liver focus (review) 979 Alkyl/allyl sulfides liver enzyme activity and 78 Asthma fruit processing enzymes and 8.III ... occu- Allergens glue and plastic 3.VIII ... test for rat urinary pational and ethanolamines 8.III ... occupational and proteins 3.XI ... threshold for airborne latex 4.II pectin 79 Allergy (see also Anaphylaxis) bovine serum albumin 4.III Atherosclerosis dietary fish oils and 663 ... malonaldehyde ... carmine 77 ... epoxypropane 3.IX ... herbal tea 6.1 formation and Probucol 841 . inhaled nicotine 8.IV ... latex and fruit 9/10.11 ... Atractyloside biochemistry and toxicology 335 latex rubber and children 3.X ... menthol testing 9/10.II Auraptene anticancer effects 9/10.III carcinogenic ... Nail varnish components 12.1V ... peanut dose protection 149 ... citrus fruits and anticarcinogenicity threshold 3.1] ... peppermint oil testing 9/101] ... 4.11] piperazine diacrylamide 3.VIII ... protease 6.1V ... Avocado osteoarthritis treatment 4.III sunscreens and photocontact 3.XII ... tin 12.III ... 2,2’-Azobis(2-amidinopropane)dihydrochloride dermatitis 2,4,6-tris(dimethylaminomethy])phenol 9/10.VI from 9/10.VI “Alta” depigmentation and 8.1V Aluminium low dose toxicity 6.III ... oral dose and biliary vy. urinary excretion 505 Amaranth immunosuppression and 3.1 Bacteria intestinal growth and tannic acid 1053 Ames Salmonella typhimurium benzaldehyde mutagenic in Baking mutagenicity effect on Agaricus bisporus extracts new strains 6.1V 315 Amino acids daily requirements 8.1 Balkan endemic nephropathy haematotoxicity and 245 Amino peptidase safety evaluation of enzyme from Asper- Beans see specific types gillus niger 781 Bee toxicity and biological properties of propolis 347 Anaphylaxis carboxymethylcellulose 79 ...carmine 149... Beef heterocyclic amines content after cooking by different curry and 8.II ... millet 3.1] ... pine nuts 4.III ... methods 279 rambutan 12.11 ‘Bee glue’ see Propolis Anethole taste loss 9/10. VIII Benchmark dose comparison with NOAEL for carbenda- Angiosarcoma vinyl! chloride and 12.III zim toxicity 37 Antibacterial agents acylamino acids and properties of Benzaldehyde mutagenic in new Ames Salmonella typhi- myristoyl-methionine 771 murium strains 6.1V Anticancer properties 4-methylsulfinylbutyl glucosinate 8.1 Benzene DNA binding 3.VII, 3.VIII ... multiple myeloma ... auraptene 9/10.III ... carotenoids 3.V ... curcumins and 151 18 Index of Subjects Benzola|pyrene fruit and vegetables protective effect Cardioprotection grape juice 4.III ... salicylates 77 against clastogenicity 637 Cardiovascular disease (see also Heart disease) methyl Betaine chloroform hepatotoxicity and 655 chloride 8.1] Beverages sucrose acetate isobutyrate (SAID) toxicity Cardiovascular system soya phytoestrogens 3.1] studies (1988) 81 3-Carene guinea pig responses to 6.III Bile acids colonic phase I and II xenobiotic metabolizing Carmine allergy 77 ... anaphylaxis 149 enzymes 601 B-Carotene modulation of sister-chromatid exchanges 897 Biphenyl genotoxicity 3.VI Carotenoids anticarcinogenic effects 3.V ... breast cancer Births ratio of male to female in industrialized countries and 3.V ... influence on cyclophosphamide and dioxi- 6.V dine clastogenic activities | Bis(2-ethylhexyl) phthalate perinatal toxicity 963 Cashew nuts pectin cross-sensitization with 9/10.1] Bisphenol A_ genotoxicity 3.XI oestrogenic activity Castor oil fatty acids polyglycerol polyricinoleate (PGPR) 6.111, 9/10.1V glyceran ester 719 Bitter gourd fruits effect on enzyme activity and carcino- Cataracts vitamin C and 78 gen activation 475 CCK-B/gastrin receptor ligand CI-988 gastric effects in Bladder tumours sodium ascorbate and 9/10.1 cynomolgus monkeys 61 Blood-brain barrier T-2 toxin permeability and monamine Cell cycle arrest fumonisin B, sphingolipid concentration oxidase activity 955 and cyclin dependent kinase 791 Blood pressure (see a/so Hypertension) weight loss and Cellulose triacetate prostate cancer and fibre manufacture reduction of sodium intake 6.11 3.VII Bone mass_ milk and young women 78 Children diet and cancer in adults 3.1II ... latex rubber Bovine serum albumin allergy 4.1II allergy 3.X ... peanut allergy persistence 8.II ... vehicle Brain methylmercury exposure 153 exhaust gases and cancer 6.V ... zinc and growth 3.V Breast cancer alcohol and 4.1 ... carotenoids and 3.V ... Chinese tea low cholesterol 149 dietary fat and 4.1 ... green tea and 8.II ... occupational p-Chlorobenzotrifluoride inhalation toxicity 3.XI xenoestrogens 9/10.VI ... smoking and 9/10.X Chloroform betaine and hepatotoxicity 655 Breast implants connective tissue disorders 3.XI f-Chioroprene vapour carcinogenicity 9/10.VI Brick tea concentration and safety evaluation of fluorine Chiorpropham toxicity and sea urchin embryos 9/10.V in Pu’er and Bianxiao types 1061 Cholesterol Chinese tea and low levels 149 ... field beans British Toxicology Society BTS report on in vitro toxi- and 3.111 ... full-fat rice bran and blood 9/10.III ... cology 153 psyllium-enriched cereals and blood 77 ... rhubarb stalk Broccoli 4-methylsulfinylbutyl glucosinate anticancer fibre and 3.111 ... soya milk and 3.1] properties 8.1 ... colorectal cancer and 12.11 Cholic acid modulation of xenobiotic metabolizing Brussels sprouts liver enzymes and 4.II enzymes 601 1,3-Butadiene mutagenicity in man 3.VIII Choline dimethylamine formation and diet 923 Butter oesophageal cancer and 9/10.1I Chromosomes aberrations and chronic feeding of MeIQ Butylated hydroxyanisole (BHA) forestomach carcinogeni- 467 acesulfame-K and damage 3.1 meiotic city 299 ... rat strain sensitivity to carcinogenicity 299 segregation and quercetin diet, Drosophila melanogaster tert-Butylhydroquinone distribution and excretion 907 585 toluene effects in print workers 6.III ... vitamin B,» and damage 9/10.III C1-988 CCK-B gastrin receptor ligand gastric effects in Ca** release pathway y-hexachlorocyclohexane apoptosis cynomolgus monkeys 61 induction and 513 Cigarettes (see also Smoking ... Tobacco) flavoured 9 Cadmium osteoporosis risk factor 9/10.V . phytase effect lO.1X lung carcinogenicity and filters 153 ... primary on accumulation 7 tobacco heating design 7.1, 169... in vitro toxicology of Caffeine Frog Embryo Teratogenesis Assay~ Xenopus mainstream smoke condensate 183... in vitro toxicology (FETAX) evaluation of developmental toxicity of 59! of mainstream whole smoke 183 ... smoke from new ... green tea and induction of hepatic phase Il enzymes type less mutagenic 6.V 617 ... SIDS (sudden infant death syndrome) 3.1 Clastogenicity carotenoids influence on cyclophosphamide Calcium colon cancer and drinking water 150 prostate and dioxidine | fruit and vegetables protective effect cancer and 4.1 ... release pathway, )-hexachlorocyclo- against cyclophosphamide and benzo[a]pyrene 637 hexane apoptosis induction and 513 Coffee gastrointestinal cancer 4.1 ... heart disease and 3.1 Cancer see Carcinogenicity ... Tumours Helicobacter pylori 150 modulation of metal- Capsaicinoids carcinogenicity and 1065 induced genotoxicity by Maillard reaction products Carbamates Propoxur carcinogenicity 1125 trom 543 Carbaryl immune system and 12.111 Colon cancer broccoli and 12.11 .. . diallyl components of Carbendazim toxicity comparison of NOAEL and bench- garlic and human cells 761 . drinking water calcium mark dose 37 130 iron and manganese superoxide dismutase Carbodiimide — sensitization 9/10. VIII (MnSOD) activity in 819 ... pinto beans and 3.III ... Carbofuran toxicity 6.11! squalene and 3.1\ Carbon disulfide occupational exposure 9 10.‘ Colophony fumes and respiratory effects 151 patch Carboxymethyleellulose anaphylaxis 79 testing control 12.111 Carcinogenicity auraptene protection 1!49 available Connective tissue breast implants and disorders 3.XI experimental testing models 997 butylated hydroxy- Cooking HCA content beef 279 ... pork 289 anisole (BHA) 299 capsaicinoids 1065 Cooking oils polyunsaturated fatty acids (PUFA) in 8.1 i - chloroprene 9/10.VI ... cigarettes and filters 153 Copper toxicity and taurine 239 fragrances 687 ... heterocyclic amines 879 nickel 9 Cosmetics formaldehyde in 3.XIl mineral oils and 10.VI photocopier toner 9/10.VIII piperony! arthritis 4.1\ skin irritancy testing in man 3.XII butoxide 9/10.1V ... propoxur 1125 review of short- Coumarin unscheduled DNA synthesis in liver slices 647 and intermediate-term testing 979, 997 Creatine supplements and kidney function 8.1] sucTOSe acetate isobutyrate (SAID) 111 Cruciferous vegetables induction of glutathione S-transfer- Carcinogens potency labelling 3.XII Thai \ egetables ase and quinone reductase by glucosinolate derivatives and activation of 475 65 Index of Subjects 19 Curcumins anticarcinogenic effects 3.V Enzymes Armillariella tabescens, aflatoxin B, detoxification Curry anaphylaxis and 8.II by 563 ... colonic phase I and II xenobiotic metabolizing Cyclin dependent kinase fumonisin B, sphingolipid con- 601 ... cytochrome P450 role in quinalphos toxicity of centration and cell cycle arrest 791 antioxidant 437 ... fruit processing and asthma 8.III ... Cyclohexylamine plasma SH group oxidation enhance- improved testing by detergents 9/10.VII ... induction by ment 755 glucosinolate derivatives 365 ... microsomes 4.IV ... Cyclophosphamide carotenoids influence on clastogenesis | screening for respiratory sensitization by detergent 80 ... fruit and vegetables protective effect against clasto- Epoxypropane allergy 3.1X genicity 637 Epoxy resin hardener allergy 9/10.VI Cynomolgus monkeys CCK-B/gastrin receptor ligand CI- Equol cytochrome P450 inhibition 375 988 gastric effects in 61 Erratum primarily tobacco heating cigarette (TOB-HT) Cystamine bislactamide allergy 9/10.VIII and chemical composition of mainstream smoke 7.1 Cytochrome P450 inhibition by isoflavonoids (genistein . . . Erythritol safety data review 1139 equol) 375 ... role in quinalphos toxicity of antioxidant Ethanolamines occupational asthma and 8.III enzymes 437 3-Ethyl-1-propanol toxicity 151 Cytokines type 2 induction and platinum salt exposure 199 Ethylenebis(dicarbamate) genotoxicity 3.VI Ethylene glycol monomethyl ether genotoxicity 4.II Ethylene glycol mono-n-butyl ether acute toxicity in guinea DDT isomers _ oestrogenic activity 150 pigs 825 Decamethylcyclopentasiloxane inhalation toxicity 9/10.VII Ethylene oxide airborne contact dermatitis 12.II] DEHP low toxicity in primates 8.III 2-Ethylhexanoic acid oral toxicity 9/10.VII ... subchronic Deoxycholic acid modulation of xenobiotic metabolizing oral toxicity 429 enzymes 601 2-Ethylhexanol inhalation study 8.III ... NOAEL (no- Depigmentation ‘‘alta” and 8.1V observed-adverse-effect level) 165 ... vapour inhalation Dermatitis airborne contact , ethylene oxide 12.III ... 2,2’- toxicity 165 azobis(2-amidinopropane)dihydrochloride 9/10.VI 5-Ethylidene-2-norborene genotoxicity potential 8.II] Desmutagenicity Lactobacillus acidophilus cultured milk EU/COLIPA Phototoxicity screen study 9/10.X and tauco 805 Eye Draize irritation test and surfactant formulations 209 Detergents improved testing of enzymes 9/10.VII . irritation tests for oil water emulsions 47 ... low Detoxification aflatoxin B,; by enzymes of Armillariella volume irritation test and surfactant formulations 209 tabescens 563 . in vitro irritation test 47 ... surfactant formulations Dially! sulfide/disulfide arylamine N-acetyltransferase ac- 209 ... wine and age-related macular degeneration 3.1] tivity in human colon cancer cells 761 Diet childhood and cancer in adults 3.III ... lung cancer and 3.VI ... oral cancer and 3.III Dietary fat breast cancer and 4.1 False positives local lymph node assay and predictive skin N,N-Diethylaniline genotoxicity 3.VI, 3. VIII sensitization tests 327 Diethylene glycol dimethyl ether toxicity 9/10. VII Fats (see also Lipids) mood changes and diet 3.IV ... N,N-Diethylethanolamine toxicity 9/10. VIII trans-unsaturated and heart disease 77 Diethylnitrosamine vitamin E and necrogenicity 929 Fatty acids (see also Polyunsaturated fatty acids Digestive tract cancer see Gastrointestinal cancer (PUFA)) long chain polyunsaturated and infant devel- Diisocyanates mutagenicity testing 6.1V opment 12.I ... trans-unsaturated and heart disease 77 Dimethylamine formation from amine precursors 923 Dimethyl mercury extreme human toxicity 9/10.VI Fertility acetochlor and 78 Dioxidine carotenoids influence on clastogenesis | Fibre laxatives flatulence and 3.III Dioxin cancer in Seveso 153 Field beans cholesterol and 3.III Diterpenoid glycosides biochemistry and toxicology 335 Fish stir frying and MelIQx bacterial mutagen 3.V 2,5-Di(tert-butyl)-1,4-hydroquinone nerve damage 3.X Fish oils dietary, atherosclerosis and 663 Dithiocarbamate accelerator residues risk assessment and Flatulence fibre laxatives and 3.III latex-based medical devices 849 Flavanols green tea and induction of hepatic phase II Divinylbenzene inhalation toxicity 151 enzymes 617 DNA §agaritine and binding 971 ... benzene binding 3.VII, Flavonoids oestrogenic activity and 9/10.III ... quinone 3.VIII ... breaking activity of hydroxyfuranones in soy reductase induction and 623 sauce 305 ... coumarin and unscheduled synthesis in Flavour and Extract Manufacturers Association (FEMA) liver slices 647 ... fragmentation and y-hexachlorocy- GRAS assessment of lactone flavour ingredients 249 clohexane 513 ... mammary gland bioassay of A(a)C Flavour use of lactones 250 adduct formation 1033 ... melanoidin modulation of Flavouring substances safety evaluation principles of 529 damage 543 ... single strand breaks and Thiram 155... Flaxseed anticarcinogenic activity 3.III] unscheduled synthesis in liver slices and cooked food Fluoride long-term exposure and spermatogenesis mor- mutagens 455 ... welders and damage 4.II phology 1117 ... occupational genotoxicity 79 Docosahexaenoic acid dose—response 3.1V Fluorine concentration and safety evaluation in Pu’er Dogs methyl bromide dietary study in 575 Brick tea and Bianxiao brick tea 1061 Draize eye test oil/water emulsions 47 surfactant Folate heart disease and 3.V formulations 209 Folic acid lower homocysteine blood levels 6.11 Drinking water (see a/so Water) nitrate and cancer 4.11... Food colour UV irradiation decomposition and mutageni- spontaneous abortion and quality 6.V city 811 Drosophila melanogaster meiotic chromosome segregation Forestomach butylated hydroxyanisole (BHA) carcino- and quercetin diet 585 genicity 299 Formaldehyde cosmetics with 3.XII Fragrances respiratory effects 9/10.VIII ... SAR analyses ECVAM Task Force | skin irritation tests proposals 8.1V and potential carcinogenicity 687 Elderly heart disease 150 Freeze-drying mutagenicity effect on Agaricus bisporus Emulsions eye irritation tests for oil/water 47 extracts 315 20 Index of Subjects Frog Embryo Teratogenesis Assay—Xenopus (FETAX) Hepatic enzymes Brussels sprouts 4.I] phase II, evaluation of developmental toxicity of caffeine and flavanols and green tea 617 metabolites 591 Hepatobiliary system sucrose acetate isobutyrate (SAID) Fructose prostate cancer and 4.1 and human function 141 Fruit citrus, Auraptene and anticarcinogenicity 4.III ... Hepatotoxicity 2-nitropropane and green tea protective processing enzymes and asthma 8.III ... protective effect effects 1043 chloroform and betaine 655 against cyclophosphamide and benzo[a]pyrene clasto- microsomal enzyme induction and 831 genicity 637 Herbal tea allergy 6.II Fumonisin B, developmental toxicity and pregnancy 673 Heterocyclic amines content in beef cooked by different inhibition of sphingolipid biosynthesis 497 methods 279 ... formation, occurrence, intake and pregnancy and 397 ... sphingolipid concentration, cyclin carcinogenicity review 879 ... gravy content and meat dependent kinase and cell cycle arrest 791 drippings 279 ... mammary gland bioassays and A(a)C 1033 Hexachlorobenzene occupational toxicity 6.II] Garlic attenuation of iron-nitrilotriacetate (Fe-NTA)- y-Hexachlorocyclohexane apoptosis induction and intra- mediated renal oxidative stress 485 ... diallyl compo- cellular Ca** release pathway 513 ... DNA fragmenta- nents and human colon cancer cells 761 ... hypertension tion and 513 and 77 ... lipid-lowering effects 9/10.II Hexamethylphosphoramide oral toxicity 151 Gastrointestinal cancer (see a/so Colon cancer) aspirin and Homocysteine folic acid and vitamin B,> lower blood levels 6.11 6.V ... tea/coffee and 4.1 Genistein cytochrome P450 inhibition 375 a-Hop acids subchronic toxicity in dogs 915 Genotoxicity biphenyl 3.VI ... bisphenol A 3.XI ... bone Human immunodeficiency virus (HIV) Lactobacillus reuteri marrow, sennosides 937 ... N,N-diethylaniline 3.VIII ... supplement safety and tolerance 1085 Ethylenebis(dicarbamate) 3.VI ... ethylene glycol mono- Hydroquinones dermal cream application and toxicity 609 methyl ether 4.II ... 5-ethylidene-2-norborene 8.III ... ... genotoxicity 3.XI ... nephrotoxicity and 609 fluoride 79 ... glyphosate 12.III ... hydroquinones 3.X]I p-Hydroxybenzoic acid oestrogenicity 3.1 . isopropylammonium glyphosate 3.VII ... lignans, Hydroxyfuranones DNA breaking activity in soy sauce plant 6.1V ... lipids peroxidation 9/10.III ... modulation 305 of metal-induced by Maillard reaction products from Hypertension (see also Blood pressure) garlic and 77 ... coffee 543 ... nitroanilines 3.1X ... nitrobenzene 3.1X ... linseed oil and 77 ... salt intake and 8.1 ... sugar intake organophosphate 3.VI ... printing inks and pigments and 4.111 8.11 ... propyl gallate 3.1 ... pyrethroids 3.VII ... rimsulfron 12.111... roundup 3.VII ... safrole 3.1V ... soy sauce 9/10.IV ... sucrose acetate isobutyrate (SAID) IgA monoclonal antibodies =vomitoxin-induced and nephro- lack of 127 ... 1,2,3,4-tetrahydronaphthalene-|-hydro- pathy 1095 peroxide 9/10.VII ... titanium oxide after irradiation Immunoaffinity column-linked HPLC ochratoxin A tox- 152 ... triazine 8.1! ... trimethylbenzenes 8.III ... icity 445 vinclozolin’ 12.111 Immunoassay ochratoxin A toxicity 445 Gestation simmondsin or defatted jojoba meal effects on Immunosuppression amaranth and 3.1... tartrazine and 3.1 rat 13 Immunotoxicity patulin and 1107 Ginseng anticancer effects 9/10.1V Indian smoking products alkaloids in tobacco smoke 1131 Glucobrassicins indole-3-carbinol prevention of cyclopho- Indigo carmine UV irradiation and mutagenicity 12.1 samide-induced micronucleus formation 975 Indole-3-carbinol prevention of cyclophosamide-induced Glucosinolate enzymes induction by derivatives of 365 micronucleus formation 975 Glucuronosyl transferases green tea and 617 Insulin resistance and vitamin D deficiency 6.1 ... trichlor- Glutathione S-transferase green tea and 617 ... induction oethylene and 4.1] by glucosinolate derivatives from cruciferous vegetables Interleukin-1/ == vomitoxin modulation of secretion 409 365 ... Thai vegetables effect on activity 475 Interleukin-6 vomitoxin modulation of secretion 409 Glyceran esters polyglycerol polyricinoleate (PGPR) and Intestine (see also Colon cancer Gastrointestinal castor oil fatty acids 719 ... safety assessment and cancer) bacterial growth and tannic acid 1053 ingestion 719 Iran EU ban on pistachio nuts 3.II Glycoalkaloids toxicology 383 Iron manganese superoxide dismutase (MnSOD) activity Glyphosate genotoxicity 12.III] and colon cancer 819 Grape juice cardioprotection and 4.11] lron-nitrilotriacetate (Fe-NTA) garlic oil attenuation of GRAS (Generally Recognized as Safe) FEMA assessment oxidative renal stress 485 of lactone flavour ingredients 249 Irradiation titanium oxide and genotoxicity 152 Gravy HCA content and meat drippings 279 Irritants air fresheners 8.1V Green tea anticarcinogen effects 3.VI ... anti-genotoxicity Ischaemic heart disease (see also Heart disease) whole 78 ... breast cancer and 8.II ... caffeine and flavanols grains and 12.1] induction of hepatic phase II enzymes 617 ... hepato- Isoflavonoids cytochrome P450 inhibition 375 toxicity protective effects and 2-nitropropane 1043 Isohumulones subchronic toxicity in dogs 915 Guar gum partially hydrolysed subchronic toxicity 3.II Isopropylammonium glyphosate genotoxicity 3.VII Guinea pigs ethylene glycol mono-n-butyl ether acute toxicity in 825 Jet fuel lung toxicity 9/10.VII Jojoba defatted meal effects on rat gestation 13 Haematotoxicity Balkan endemic nephropathy and 245 Headaches triethylamine and 3.1X Heart disease coffee and 3.1 ... elderly 150 ... folate and Kidney cancer vegetables and 9/10.III vitamin Bs 3.V ... ischaemic, whole grains and 12.11... Kidneys (see a/so Renal stress) creatine supplements and passive and active smoking 3.XI ... trans-unsaturated 8.11... oral dose aluminium and urinary excretion 505 fats 77 ... turmeric 4.11] Kojic acid oral administration and thyroid tumour induc- Helicobacter pylori alcohol, coffee 150 tion 697 Index of Subjects Konjac flour sensitization 3.V 4-Methylsulfinylbutyl glucosinate anticancer properties in broccoli 8.1 Methylxanthines developmental toxicity 591 Lactic acid bacteria see Lactobacillus sp. Microcystin fatal poisoning 9/10.VIII Lactobacillus acidophilus desmutagenicity of cultured milk Micronuclei Thiram mutagenicity 155 and tauco 805 Microsomes enzyme induction and hepatotoxicity 831... Lactobacillus reuteri supplement safety and tolerance and in vitro solvents and enzymes 4.I'V potential HIV infections 1085 Milk bone mass and young women 78 Lactobacillus rhamnosus aflatoxin B, binding by 321 Millet anaphylaxis 3.1] Lactones_ chemical identity 250 ... FEMA GRAS assess- Monamine oxidase T-2 toxin blood-brain barrier per- ment of flavour ingredients 249 ... flavour use 250 ... meability and activity 955 metabolism 251 ... toxicology 255 Monascus_ anti-mutagenicity of pigments 77 Latex allergy and fruit 9/10.II ... allergy in children 3.X Monoethanolamine reproductive toxicity 152 ... glove quality control 3.X ... medical devices and Monooxygenases_ Thai vegetables effect on activity 475 dithiocarbamate accelerator residues risk assessment 849 Mood changes _ low fat diet and 3.1V . non-allergenic respiratory problems 3.XI ... rate of Mortality statistics Albania adult rates 3.1V sensitization to 6.III ... threshold for airborne allergens Mouse hairless model for chronic toxicity of topical 4.1] chemicals 867 Laxatives, fibre flatulence and 3.III Mouse skin tumour assay review 979 LDgpo tests 3. XIII Multiple myeloma benzene and 151 Lead phytase effect on accumulation 7 Mushrooms see specific types Lignan genotoxicity of plant 6.1V Mutagenicity aspartame 12.1 ... baking effect on Agaricus Linoleic acid conjugated toxicity 391 bisporus extracts 315 ... benzaldehyde in new Ames Linseed oil hypertension and 77 Salmonella typhimurium strains 6.1V ... 1,3-butadiene Lipids (see also Fats) fat intake and serum 3.IV ... 3.VIII ... cooking oils and fumes 12.11 ... diisocyanates, peroxidation and genotoxicity 9/10.1I] testing 6.1V ... indigo carmine 12.1... terpineol 12.1... Lithium skin disease and consumption 152 tetravinyl-tetramethylcyclotetrasiloxane 3.XII ... thiram Lithocolic acid modulation of xenobiotic metabolizing (tetramethylthiuram disulfide) and testing in mice 155... enzymes 601 UV irradiation decomposition of food colours 811 Liver (see also Hepatic enzymes) Brussels sprouts and Mutagens PBTA-1 80... and unscheduled DNA synthesis enzymes of 4.II cooked food mutagens and in liver slices 455 unscheduled DNA synthesis in slices 455 ... enzyme Mycotoxins (see also specific types) fumonisin B, and activity and alkyl/allyl sulfides 78 oral dose pregnancy 397 aluminium and excretion 505 Myristoyl-methionine antibacterial properties of acyl- Low volume eye test oil/water emulsions 47 amino acids 771 Lung carcinogenicity and cigarette filters 153 Lung cancer diet and 3.VI ... lycopene and 78 ... metal workers risk 12.II] ... theaflavins 3.VI Nail varnish components allergy 12.1V Lycopene lung cancer and 78 Nephropathy Balkan endemic 245 ... vomitoxin-induced Lymphoma mouse assays 153 IgA Mabs and 1095 Nephrotoxicity hydroquinones cream application and tox- icity 609 Maillard reaction modulation of metal-induced genotoxi- Nerves 2,5-di(tert-butyl)-1,4-hydroquinone damage 3.X city by products from coffee 543 Nickel occupational carcinogenicity 9/10.VI Malonaldehyde formation and probucol 841 Nicotine allergy to inhaled 8.1V Maltitol anticancer activity 8.1 Nitrate drinking water and cancer 4.II Mammary gland bioassay A(x)C and DNA adduct for- Nitroanilines genotoxicity 3.1X mation DNA 1033 Nitrobenzene genotoxicity 3.1X Manganese superoxide dismutase (MnSOD) iron and 2-Nitropropane green tea hepatotoxicity protective effects activity in colon cancer 819 and 1043 Meat diet, cancer and genetics 12.II N-Nitroso-N-(3-keto-1,2-butanediol)-3'-nitrotyramine tu- Medical devices dithiocarbamate accelerator residues risk mour promoter effect 631 assessment and latex-based 849 NOAEL (no-observed-adverse-effect level) antimony in Meiotic chromosome segregation in Drosophila melanoga- drinking water 21 ... comparison with benchmark dose ster On quercetin diet 585 for carbendazim toxicity 37 ... sucrose acetate isobuty- MeIQ (2-amino 3,4-dimethylimidazo[4,5-/ |])quinoline —chro- rate (SAID) 121 mosome aberrations and chronic feeding 467 ... human p-Nonylphenol oral toxicity 151 metabolism of 6.II ... stir frying fish and mutagen 3.V Nostoc flagelliforme safety evaluation as potential food Melanoidin modulation of DNA damage 543 1073 Melatonin contaminants in commercial preparations of Nutrients supplements potentially harmful 9/10.11] 6.11 Nutrition implications of macronutrient substitutes con- Menhaden oil steatosis and 555 ference report 145 Menstrual cycle PCB exposure and 3.VI Nuts (see also Peanut) cashew, pectin cross-sensitization Menthol allergy testing 9/10.II with 9/10.1I ... pine, anaphylaxis 4.III ... pistachio , EU Metals Maillard reaction products from coffee modulate ban on Iranian 3.1] induced-genotoxicity 543 Methoxychlor reproductive toxicity 150 3-Methyl-1-butanol toxicity 151 Occupational asthma ethanolamines 8.III ... pectin 79 Methyl bromide dietary study in dogs 575 ... and oral Occupational carcinogenicity nickel 9/10. VI teratogenicity 421 ... subchronic toxicity 9/10.1V Occupational exposure carbon disulfide 9/10.V Methyl chloride cardiovascular disease and 8.II Occupational exposure limits 12.111], 12.1V N-Methyl ethanolamine _ sensitising potential 6.1V Occupational toxicity genotoxicity of fluoride 79 Methylmercury maternal exposure and brain function 153 hexachlorobenzene 6.111 22 Index of Subjects Ochratoxin A human toxicity study in Tokyo 445 ... human toxicology studies 743 ... preparation, use and immunoassay and immunoaffinity column-linked HPLC biological properties 711 ... safety assessment 711 445 Polyoxyethylene surfactants instability 9/10.X Oesophageal cancer butter and 9/10.1I ... metalworking Polystyrene skin reactions 3.XII fluids and 9/10.VI Polyunsaturated fatty acids (PUFA) cooking oils and 8.1 Oestrogenic activity phthalates 79 ... p-Hydroxybenzoic ... long chain and infant development 12.1 ... n-3 , diet acid 3.1 and atherosclerosis 663 Oestrogens (see also Phytoestrogens) bisphenol A and Polyvinyl chloride (PVC) exposure and testicular cancer activity 6.1II ... DDT isomers and activity 150 ... 3.VII ... skin absorption of di(2-ethylhexyl)phthalate environment and 4.II ... flavanoids and activity 9/10.III from film 521 . occupational xenoestrogens and breast cancer 9/ Pork heterocyclic amines content after cooking by differ- 10.VI ... screening test reliability 9/10.1II ent methods 289 Oils cooking and fumes mutagenicity 12.I] ... hydrogen- Post-menopausal hot flushes soya supplements and 4.III ated vegetable, and stroke 9/10.II Potassium iodide salivary gland cancer 6.1V Olestra low-dose gastrointestinal effects 149 Pregnancy developmental toxicity and fumonisin B, 673 Oleth-3-phosphate sensitization 80 . fumonisin B,; and 397 ... outcome after male Oleth-5-phosphate sensitization 80 pesticide exposure 3.VII Olive oil anticancer properties 8.II Primarily tobacco heating cigarette (TOB-HT) and chemi- Oral cancer diet and 3.III ... smokeless tobacco and 1015 cal composition of mainstream smoke 7.I (Erratum), 169 Oral LDsp Test validation of alternatives 12.I1V Printing inks genotoxicity of pigments 8.III Oral toxicity 2-ethylhexanoic acid and subchronic 429 Print workers chromosome effects and toluene 6.III Organophosphate genotoxicity 3.VI Probiotics Lactobacillus reuteri supplements and HIV 1085 Osteoarthritis avocado/soybean treatment 4.III Probucol blood plasma oxidation 841 ... malonaldehyde Osteoporosis cadmium risk factor 9/10.V formation and 841 Propolis toxicity and biological properties 347 Propoxur carcinogenicity 1125 p53 protein vinyl chloride exposure and mutant 6.III Propyl gallate genotoxicity 3.1 Paraffin long-term feeding of liquid 3.X Prostate cancer calcium, fructose and vitamin D 4.I ... Paraquat respiratory tract and 3.VI cellulose triacetate fibre manufacture 3.VII ... selenium Patulin immunotoxicity and 1107 and 12.1] ... vitamin E supplements 6.1 PBTA-1 new mutagen 80 Protease allergy 6.1V PCBs see Polychlorinated biphenyls (PCBs) Psyllium enriched cereals and blood cholesterol 77 Peanut allergy and dose threshold 3.1] ... allergy persist- PVC see Polyvinyl chloride (PVC) ence in children 8.1] Pyrethroids genotoxicity 3.VII Pectin cross-sensitization with cashew nuts 9/10.II ... occupational asthma and 79 Pectinesterase safety of 12.1 Quercetin meiotic chromosome segregation in Drosophilia Peppermint oil allergy testing 9/10.II melanogaster 585 Pesticides pregnancy outcome after male exposure 3.VII Quinalphos cytochrome P450 role in toxicity of antiox- . regulatory testing and second species choice 9/10.V idant enzymes 437 . Sheep reproductive hormones and 9/10.IV Quinone reductase flavonoids and induction 623 Petrochemicals abortion and 3.VIII induction by glucosinolate derivatives from cruciferous Petrol multiple chemical sensitivity 9/10. VII vegetables 365 Pharmaceutical coatings Aquacoat" ECD ethyl cellulose aqueous dispersion toxicity and 705 Pharmacokinetics sucrose acetate isobutyrate (SAID) 95 . Sucrose octaisobutyrate (SOIB) 95 Rambutan anaphylaxis 12.II Phenylalanine daily requirements 8.1 Rat liver focus assay (review) 979 o-Phenyl phenol genotoxicity 3.VI Rats strain sensitivity to BHA carcinogenicity 299 Phosphine inhalation toxicity 9/10.V Rat urinary proteins allergens test 3.XI Photocopier toner lung carcinogenicity 9/10.VIII Reactive oxygen species shark-cartilage containing prep- Phototoxicity screen EU/COLIPA study 9/10.X aration scavenger activity 1079 di(2-ethythexy!)Phthalate percutaneous absorption from Rectal cancer broccoli and 12.1] PVC film 521 Renal stress garlic oil attenuation of iron-nitrilotriacetate Phthalates estrogenic activity 79 (Fe-NTA)-mediated oxidative 485 Phytase effect on zinc bioavailability and cadmium and Reproduction acrylic acid and 152 ... simmondsin or lead accumulation in rats 7 ... sensitization 79 defatted jojoba meal effects on rat gestation 13 ... Phytoestrogens (see also Odcstrogens) benefits 8.1 sucrose acetate isobutyrate (SAID) and 135 cardiovascular system and soya 3.11 ... resveratrol 3.1] Respiratory diseases acrylates 3.1X ... triphenylmethane Phytosterols lipid metabolism and 9/10.1 triisocyanate and 151 Pigments anti-mutagenicity of Monascus 77 ... printing Resveratrol phytoestrogen 3.1 inks and genotoxicity of 8.III Retinal modulation of sister-chromatid exchanges 897 Pine nuts anaphylaxis 4.IIl Retinol skin cancer suppression 150 Pinto beams colon cancer and 3.III Rhubarb cholesterol and stalk fibre 3.11] Piperazine diacrylamide allergy 3.VIII Riboflavin modulation of sister-chromatid exchanges 897 Piperonyl butoxide carcinogenicity 9/10.1V Rice full-fat bran and blood cholesterol 9/10.III Pistachio nuts EU ban on Iranian 3.1 Rimsulfron genotoxicity 12.11] Platinum type 2 cytokines induction and salt exposure 199 Roundup genotoxicity 3. VII Polychlorinated biphenyls (PCBs) exposure and menstrual Rubber latex see Latex cycle 3.V1... fish contamination and mink reproduction 9 10.1V Polyglycerol polyricinoleate (PGPR) carcinogenic poten- tial 747 digestion, metabolism and excretion 719 ... Saccharin long-term study in monkeys 6.I

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