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First Aid for the USMLE Step 1 2015 PDF

769 Pages·2015·39.177 MB·English
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FIRST AID FOR THE® USMLE STEP 1 2015 TAO LE, MD, MHS VIKAS BHUSHAN, MD Associate Clinical Professor Diagnostic Radiologist Chief, Section of Allergy and Immunology Los Angeles Department of Medicine University of Louisville MATTHEW SOCHAT, MD PATRICK SYLVESTER Resident, Department of Neurology The Ohio State University College of Medicine New York University School of Medicine Class of 2015 MICHAEL MEHLMAN KIMBERLY KALLIANOS, MD University of Queensland, Australia Resident, Department of Radiology and Biomedical Imaging Class of 2015 University of California, San Francisco New York / Chicago / San Francisco / Lisbon / London / Madrid / Mexico City Milan / New Delhi / San Juan / Seoul / Singapore / Sydney / Toronto FAS1_2015_00_Frontmatter_i-xxiv.indd 1 11/9/14 12:35 AM Copyright © 2015 by Tao Le and Vikas Bhushan. All rights reserved. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without the prior written permission of the publisher, with the exception that the program listings may be entered, stored, and executed in a computer system, but they may not be reproduced for publication. ISBN: 978-0-07-184007-1 MHID: 0-07-184007-9 The material in this eBook also appears in the print version of this title: ISBN: 978-0-07-184006-4, MHID: 0-07-184006-0. eBook conversion by codeMantra Version 1.0 All trademarks are trademarks of their respective owners. Rather than put a trademark symbol after every occurrence of a trademarked name, we use names in an editorial fashion only, and to the benefit of the trademark owner, with no intention of infringement of the trademark. Where such designations appear in this book, they have been printed with initial caps. McGraw-Hill Education eBooks are available at special quantity discounts to use as premiums and sales promotions or for use in corporate training programs. To contact a representative, please visit the Contact Us page at www.mhprofessional.com. Notice Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work. Readers are encouraged to confirm the information contained herein with other sources. For example and in particular, readers are advised to check the product information sheet included in the package of each drug they plan to administer to be certain that the information contained in this work is accurate and that changes have not been made in the recommended dose or in the contraindications for administration. This recommendation is of particular importance in connection with new or infrequently used drugs. 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Under no circumstances shall McGraw-Hill Education and/or its licensors be liable for any indirect, incidental, special, punitive, consequential or similar damages that result from the use of or inability to use the work, even if any of them has been advised of the possibility of such damages. This limitation of liability shall apply to any claim or cause whatsoever whether such claim or cause arises in contract, tort or otherwise. Dedication To the contributors to this and past editions, who took time to share their knowledge, insight, and humor for the benefit of students. FAS1_2015_00_Frontmatter_i-xxiv.indd 3 11/9/14 12:35 AM This page intentionally left blank Contents Contributing Authors vii General Acknowledgments xv Associate Authors viii How to Contribute xix Faculty Reviewers ix How to Use This Book xxi Twenty-Fifth Anniversary Foreword xi Common USMLE Laboratory Values xxii Preface xiii First Aid Checklist for the USMLE Step 1 xxiv Special Acknowledgments xiv ``SECTION I GUIDE TO EFFICIENT EXAM PREPARATION 1 Introduction 2 Test-Taking Strategies 18 USMLE Step 1—The Basics 2 Clinical Vignette Strategies 20 Defining Your Goal 11 If You Think You Failed 20 Excelling in the Preclinical Years 12 If You Failed 21 Timeline for Study 13 Testing Agencies 21 Study Materials 17 References 22 ``SECTION I SUPPLEMENT SPECIAL SITUATIONS 23 First Aid for the International Medical Graduate 24 First Aid for the Podiatric Medical Student 39 First Aid for the Osteopathic Medical Student 34 First Aid for the Student with a Disability 41 ``SECTION II HIGH-YIELD GENERAL PRINCIPLES 43 How to Use the Database 44 Immunology 197 Behavioral Science 47 Pathology 221 Biochemistry 61 Pharmacology 241 Microbiology 117 v FAS1_2015_00_Frontmatter_i-xxiv.indd 5 11/9/14 12:35 AM ``SECTION III HIGH-YIELD ORGAN SYSTEMS 263 Approaching the Organ Systems 264 Neurology 447 Cardiovascular 267 Psychiatry 503 Endocrine 311 Renal 525 Gastrointestinal 341 Reproductive 557 Hematology and Oncology 381 Respiratory 599 Musculoskeletal, Skin, and Connective Tissue 415 Rapid Review 623 ``SECTION IV TOP-RATED REVIEW RESOURCES 643 How to Use the Database 644 Cell Biology and Histology 649 Question Banks 646 Microbiology and Immunology 649 Question Books 646 Pathology 650 Internet Sites 646 Pharmacology 651 Mobile Apps 647 Physiology 652 Comprehensive 647 Commercial Review Courses 653 Anatomy, Embryology, and Neuroscience 647 Publisher Contacts 659 Behavioral Science 648 Abbreviations and Symbols 661 Biochemistry 648 Photo Acknowledgments 669 `` Index 687 About the Authors 743 vi FAS1_2015_00_Frontmatter_i-xxiv.indd 6 11/9/14 12:35 AM Contributing Authors DANIEL AARONSON JOUZIF IBRAHIM, MD Sackler School of Medicine Resident, Department of Anesthesiology Class of 2016 New York State University at Buffalo School of Medicine MARK D. ARD, MA MEHBOOB KALANI Editor, firstaidteam.com Loma Linda University School of Medicine University of St. Eustatius School of Medicine Class of 2016 Class of 2015 YASH CHAVDA NYIT College of Osteopathic Medicine M. SCOTT MOORE, DO Class of 2015 Resident, Department of Pathology University of Arizona School of Medicine FRANCIS DENG Washington University School of Medicine in St. Louis Class of 2016 JUDITH RAMEL, MD American University of the Caribbean NATHANIEL R. GREENBAUM Class of 2014 Sackler School of Medicine Class of 2016 NINO SIKHARULIDZE, MD ANN R. HUA Department of Endocrinology University of Texas Health Science Center at San Antonio Tbilisi State Medical University Class of 2017 JACK HUA JARED A. WHITE, MS University of Texas Health Science Center at San Antonio University of Mississippi School of Medicine Class of 2015 Class of 2016 Image and IllustratIon team PRAMOD THEETHA KARIYANNA, MD RICHARD P. USATINE, MD Resident, Department of Internal Medicine Professor, Dermatology and Cutaneous Surgery Brookdale University Hospital and Medical Center Professor, Family and Community Medicine University of Texas Health Science Center San Antonio vii FAS1_2015_00_Frontmatter_i-xxiv.indd 7 11/9/14 12:35 AM Associate Authors JESSIE DHALIWAL ERIC DAEHO KIM Western University of Health Sciences College of Osteopathic Medicine Western University of Health Sciences College of Osteopathic Medicine Class of 2016 Class of 2016 ASHWANI GORE RYAN K. MEYER St. George’s University School of Medicine Rutgers New Jersey Medical School Class of 2015 Class of 2016 JAN ANDRE GRAUMAN, MA SATYAJIT REDDY San Juan Bautista School of Medicine Alpert Medical School of Brown University Class of 2016 Class of 2015 Image and IllustratIon team WENDY E. ABBOTT JOCELYN T. COMPTON Kentucky College of Osteopathic Medicine Columbia University College of Physicians and Surgeons Class of 2015 Class of 2015 KEVIN AU JULIA KING Albany Medical College New York University School of Medicine Class of 2015 MD/PhD Candidate viii FAS1_2015_00_Frontmatter_i-xxiv.indd 8 11/9/14 12:35 AM Faculty Reviewers MARIA ANTONELLI, MD JEFFREY J. GOLD, MD Rheumatology Fellow, Department of Medicine Associate Professor, Department of Neurology Case Western Reserve University School of Medicine University of California, San Diego School of Medicine BRIAN S. APPLEBY, MD WHITNEY GREEN, MD Associate Professor, Department of Neurology Resident, Department of Pathology Case Western Reserve University School of Medicine Johns Hopkins Hospital HERMAN BAGGA, MD RYAN C. W. HALL, MD Fellow, Department of Urology Assistant Professor, Department of Psychiatry Cleveland Clinic University of South Florida ADITYA BARDIA, MBBS, MPH MARGARET HAYES, MD Attending Physician, Massachusetts General Hospital Pulmonary and Critical Care Fellow Harvard Medical School Johns Hopkins Hospital JOHN BARONE, MD JEFFREY W. HOFMANN, PhD Anatomic and Surgical Pathology BaroneRocks.com The Warren Alpert Medical School of Brown University MD Candidate BROOKS D. CASH, MD DEEPALI JAIN, MD Professor of Medicine, Division of Gastroenterology University of South Alabama School of Medicine Assistant Professor, Department of Pathology All India Institute of Medical Sciences LINDA S. COSTANZO, PhD BRIAN C. JENSEN, MD Professor of Physiology & Biophysics Virginia Commonwealth University School of Medicine Assistant Professor of Medicine and Pharmacology University of North Carolina McAllister Heart Institute ANTHONY L. DeFRANCO, PhD Professor of Microbiology and Immunology JENNIFER LE, MD University of California, San Francisco School of Medicine Associate Professor, Division of Child and Adolescent Psychiatry University of Louisville School of Medicine CHARLES S. DELA CRUZ, MD, PhD Assistant Professor, Department of Pulmonary and Critical Care Medicine GERALD LEE, MD Yale School of Medicine Assistant Professor, Department of Pediatrics University of Louisville School of Medicine CONRAD FISCHER, MD Residency Program Director, Brookdale University Hospital KACHIU LEE, MD, MPH Brooklyn, New York Associate Professor of Medicine, Physiology, and Pharmacology Department of Dermatology Touro College of Medicine Harvard Medical School STUART D. FLYNN, MD WARREN LEVINSON, MD, PhD Dean, College of Medicine Professor, Department of Microbiology & Immunology University of Arizona College of Medicine, Phoenix University of California, San Francisco School of Medicine ix FAS1_2015_00_Frontmatter_i-xxiv.indd 9 11/9/14 12:35 AM

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