Fight Heart Disease with Vitamins and Antioxidants

246 Pages·2014·2.55 MB·English

by  Kedar N. Prasad Ph.D.

HealtH/NutritioN $16.95 P
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“Kedar Prasad has put forward an original and logical approach for prevention and a
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improved management of heart disease. His suggested strategy is simple and easy to
follow and involves no potentially harmful drugs. I strongly recommend this book.”
StepHeN C. BoNdy, pH.d., professor, Center for Occupational and
Environmental Health, Department of Medicine, University of California, Irvine
F
In this practical scientific guide, leading researcher in cancer, heart disease, and diabetes
prevention Kedar N. Prasad, Ph.D., reveals the latest revolutionary discoveries on the i
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use of antioxidants and micronutrients to treat heart disease. He details how the proper
combinations of vitamin and antioxidant supplements can greatly increase the effective- h
ness of standard medical treatments for heart disease as well as help balance cholesterol
t
levels and blood pressure, minimize plaque and clot formation, reduce angina and ath-
erosclerosis, and prevent the onset of heart disease despite family history. H
Prasad shows how chronic inflammation, oxidative stress, homocysteine levels,
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and free radical damage are the chief culprits in the progression of heart disease and
that merely changing your diet and activity level and regulating cholesterol and blood a
pressure cannot fully counteract an unhealthy internal state. He provides an easy-to- r
follow daily supplement regime for multiple age groups to target free radical damage t
and cell injury and stop the progression of heart disease and its related complications.
Sharing the scientific data on familial heart disease and antioxidant use, he debunks D
the flawed conclusions of the medical community that vitamins and antioxidants are
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ineffective for heart disease, revealing how their studies focused on specific micronu- s
trients rather than synergistic combinations. e
Offering the missing complement to the standard care of medications, diet, exer-
a
cise, and lifestyle changes promoted by mainstream medicine, this guide provides a
s
powerful approach to heart disease prevention, treatment, and care.
e
KEDAR N. PRASAD, Ph.D., is the chief scientific officer of the Premier Micronutrient
Corporation, the former director of the Center for Vitamins and Cancer Research aw
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at the University of Colorado School of Medicine, and the former president of the dit
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International Society of Nutrition and Cancer. The author of Fight Diabetes with
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Vitamins and Antioxidants and coauthor of Fighting Cancer with Vitamins and n
i
Antioxidants, he lives in the San Francisco Bay Area. tt
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HEALING ARTS PRESS as
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ROCHESTER, VERMONT t
s
www.HealingArtsPress.com
Cover design by Peri Swan
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Fight Heart
Disease
Vitamins
with and
Antioxidants
Kedar N. Prasad, Ph.D.
Healing Arts Press
Rochester, Vermont • Toronto, Canada
FiHeDi.indd 1 10/21/14 10:55 AM
Healing Arts Press
One Park Street
Rochester, Vermont 05767
www.HealingArtsPress.com
Healing Arts Press is a division of Inner Traditions International
Copyright © 2014 by Kedar N. Prasad, Ph.D.
All rights reserved. No part of this book may be reproduced or utilized in any form
or by any means, electronic or mechanical, including photocopying, recording, or by
any information storage and retrieval system, without permission in writing from
the publisher.
Note to the reader: This book is intended as an informational guide. The remedies,
approaches, and techniques described herein are meant to supplement, and not to be a
substitute for, professional medical care or treatment. They should not be used to treat
a serious ailment without prior consultation with a qualified health care professional.
Library of Congress Cataloging-in-Publication Data
Prasad, Kedar N.
Fight heart disease with vitamins and antioxidants / Kedar N. Prasad, Ph.D.
pages cm
Includes bibliographical references and index.
ISBN 978-1-62055-296-4 (paperback) — ISBN 978-1-62055-172-1 (e-book)
1. Heart—Diseases—Diet therapy. 2. Heart—Diseases—Nutritional aspects. 3.
Vitamin therapy. 4. Antioxidants—Therapeutic use. I. Title.
RC684.D5.P73 2014
616.1'20654—dc23
2014015926

Text design and layout by Virginia Scott Bowman
This book was typeset in Garamond Premier Pro and Helvetica Neue with Avant
Garde and Helvetica Neue used as display typefaces
To send correspondence to the author of this book, mail a first-class letter to the
author c/o Inner Traditions • Bear & Company, One Park Street, Rochester, VT
05767, and we will forward the communication, or contact the author directly at
[email protected].
FiHeDi.indd 2 10/21/14 10:55 AM
Contents

Foreword by Jeffrey L. Boone, M.D. v

Preface Why Should You Read This Book? ix
1
What Is Heart Disease? History, Types, 1
and Cost to Society
2
Causes of Heart Disease:
The Healthy Human Heart and Risk Factors
That Threaten It 14
3
Compounding Factors of Heart Disease:
Oxidative Stress and Inflammation 31
4
The Antioxidant Defense System:
History and Actions, Sources, and Properties
of Antioxidants 48
5
The Antioxidant Defense System Further
Defined: Properties, Doses, and Risks 66
6
The Search for Prevention:
The Laboratory and Epidemiologic Studies 84
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7
The Search for Prevention Further Defined:
The Intervention Studies 99
8
Clinical Studies to Date:
A Flawed Methodology 132
9
Heart Disease Prevention and Management:
Multi-micronutrients, Diet, and Lifestyle
Recommendations 144

afterword The Road Ahead 168

aPPendix Values of Recommended Dietary Allowances
(RDA)/Dietary Reference Intakes (DRI) 172
■■■

Abbreviations and Terminologies 199

Bibliography 202

About the Author 218

Index 220
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Foreword
Jeffrey L. Boone, M.D.
Medical training encompasses the basics of human nutrition as well
as the biochemistry and history of elemental vitaminology and nutri-
tion science. However, as a profession and as a society, we have moved
beyond the mere daily allowances required to avoid rickets, scurvy, and
the like into a world that demands erudite answers regarding optimal
dietary supplementation. As a physician specializing in preventive cardi-
ology, I stood at the center of this controversy amidst patients in search
of answers, often skeptical medical colleagues, and a growing body of
literature debating the effectiveness of dietary supplementation. Then I
met Kedar N. Prasad, Ph.D., a scientist with the brilliance and academic
credibility to illuminate the truth with regard to dietary supplements.
I was first attracted to Prasad’s work with NASA as a radiation biol-
ogist charged with helping to protect military personnel from the dan-
gers of radiation exposure. His groundbreaking work delineated a unique
supplement that seemed to protect the subject from the DNA damage
and eventual carcinogenesis caused by ionizing radiation. Persuaded by
Prasad’s detailed research, I began to use his protective formulation of
dietary supplements to shield my patients’ internal cellular environment
from the radiation they received from ultrafast CT scans of the heart. A
recent study in Germany showed Prasad’s radiation-protection formula-
tion reduced double-strand DNA breakage by 58 percent versus placebo
v
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vi Foreword
in a study of people before and after diagnostic CT scanning. To this
day I continue to use Prasad’s formula before CT scans to mitigate the
effects of radiation exposure caused by advanced imaging.
As I continued with my work in preventive cardiology, Prasad
and his group initiated numerous research trials with disparate groups
across the country. I tracked these developments closely, always seek-
ing to remain on the cutting edge of disease prevention. Over the years
research emerged that demonstrated a myriad of benefits to Prasad’s
formulas. Supplement formulations developed around his ideas were
shown to enhance immunity, reduce oxidative stress, improve hearing,
promote concussion recovery, lessen tinnitus, treat post-traumatic stress
disorder, and reduced inflammation! Such widespread benefits can be
traced back to the unifying concepts of cellular protection from the
basic tenets of Prasad’s work—the control of oxidative stress and chronic
inflammation. In fact, over the last thirty years it has become increas-
ingly apparent throughout the medical world that most disease and
even aging itself can be traced to a core of inflammation and oxidation.
Excited by these widespread applications, I decided to embark upon
a research trial in my own field of expertise: the prevention and eradica-
tion of heart disease and stroke. Several anecdotal cases of remarkable cho-
lesterol profile improvements were seen in my practice as I expanded my
use of Prasad’s Heart Formulation beyond radiation protection to daily
use in selected patients. These exciting results led Prasad and I to initiate
the Boone Heart Institute’s MAVRIC Trial (Multivitamin Antioxidant
Vitamin Reversal of Intima-Media Thickness of the Carotid Artery).
Our study group consisted of seventy robust professional firefighters from
South Metro Fire Rescue in Denver, Colorado. They took no medication
or other supplements for the duration of the trial. For one year these fire-
fighters took Prasad’s Heart Formulation as directed while my medical
team tracked their cardiovascular risk factors. As always, the key tenets
of the Heart Formulation* revolve around the control of the free radicals
causing oxidative stress and chronic inflammation. The Heart Formulation
*See www.multimmunity.com for product information.
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Foreword vii
accomplishes this control through a unique blend of micronutrients that
include dietary and endogenous antioxidants coupled with vitamin D,
B-vitamins, and minerals (avoiding heavy metals) in a twice-daily dosing
schedule. To our amazement, but confirming our hope, Prasad’s approach
controlled anatomic measurements of the growth of firefighter atheroscle-
rosis, as well as remarkably optimizing the firefighter cholesterol profile
(i.e., LDL [bad] cholesterol decreased from 132 mg/DL to 111 mg/DL;
HDL [good] cholesterol improved from 42 mg/DL to 51 mg/DL, which
constitutes a 30.3% improvement in LDL to HDL ratio). In addition,
echocardiographic measurements of heart stiffness (E/A ratio) improved
13 percent. To this day, I recommend Dr. Prasad’s formula to many of my
patients, often in conjunction with powerful drugs and lifestyle changes.
Read Fight Heart Disease with Vitamins and Antioxidants to see
how Kedar Prasad has provided us all with a new day of clarity in nutri-
tion science . . . but more importantly, take his formula as I do!
Jeffrey L. Boone, M.D., is an internationally recognized expert on the effects
of mental stress on the heart. He is the founder and director of the Boone Heart
Institute in Denver, Colorado. In 2007, he was selected as one of the 160 Top
Doctors in America by Men’s Health Magazine and was listed as one of the seven-
teen Top Cardiovascular Doctors in America for Men. In addition, he works as
a consultant in preventive cardiology for the Denver Broncos and the Colorado
Rockies. Dr. Boone is a member of the NFL’s Cardiovascular Committee, as
well as the founder of the NFL Alumni Association’s Cardiovascular Screening
Program, an ongoing investigation into the cardiovascular health of former NFL
players. As an international lecturer, Dr. Boone has spoken to tens of thousands
of health care professionals around the world. His unique clinical approach
focuses on aggressive prevention of cardiovascular disease, including the evalua-
tion of the cardiovascular consequences of mental stress, the early clinical use of
the latest cardiac imaging techniques, and the advanced detection and treatment
of cardiometabolic risk.
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