1600 John F. Kennedy Blvd. Ste 1800 Philadelphia, PA 19103-2899 FERRI’S CLINICAL ADVISOR, 2016 ISBN: 978-0-323-28047-1 Copyright © 2016 by Elsevier, Inc. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions. This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein). Notices Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary. Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility. With respect to any drug or pharmaceutical products identified, readers are advised to check the most current infor- mation provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibil- ity of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. ISBN 978-0-323-28047-1 Content Strategist: Suzanne Toppy Content Development Specialist: Lauren Boyle Publishing Services Manager: Catherine Jackson Project Manager: Kate Mannix Design Direction: Paula Catalano Printed in the United States Last digit is the print number: 9 8 7 6 5 4 3 2 1 Section Editors RUBEN ALVERO, M.D. RICHARD J. GOLDBERG, Professor of Obstetrics and M.D., M.S. Gynecology Psychiatrist-in-Chief Director, Assisted Reproductive Rhode Island Hospital Technologies The Miriam Hospital; Division Director REI Professor Vice Chairman for Education Department of Psychiatry and Department of Obstetrics and Human Behavior Gynecology Alpert Medical School University of Colorado Denver Brown University Aurora, Colorado Providence, Rhode Island FRED F. FERRI, M.D., HARALD A. HALL, M.D. F.A.C.P. Rheumatologist Clinical Professor Providence, Rhode Island Alpert Medical School Brown University Providence, Rhode Island GLENN G. FORT, M.D., SIDDHARTH KAPOOR, M.P.H., F.A.C.P., F.I.D.S.A. M.D., F.A.H.S. Clinical Associate Professor of Assistant Professor Medicine Department of Neurology Alpert Medical School Director, UK Epilepsy Care Network Brown University; Director, Headache Medicine Chief, Infectious Diseases Program Director, Fellowship in Our Lady of Fatima Hospital Headache Medicine Providence, Rhode Island; University of Kentucky College of Landmark Medical Center Medicine Woonsocket, Rhode Island Lexington, Kentucky iii Section Editors iv GAGAN SAHNI, M.D., IRIS L. TONG, M.D. F.A.C.C., F.A.C.P. Director Director of Cardio-Oncology Women’s Primary Care Director of Cardiology Consult Women’s Medicine Collaborative; Service Assistant Professor Cardiovascular Institute Department of Medicine Mount Sinai Hospital Alpert Medical School New York, New York Brown University Providence, Rhode Island STEVEN M. SEPE, M.D., Ph.D. Clinical Professor of Medicine Assistant Dean Boston University School of Medicine Boston, Massachusetts Preface This book is intended to be a clear and concise reference for physicians and Section III includes clinical algorithms to guide and expedite the allied health professionals. Its user-friendly format was designed to provide patient’s workup and therapy. Fifteen new algorithms have been added a fast and efficient way to identify important clinical information and to for the 2016 edition. Many physicians describe this section as particularly offer practical guidance in patient management. The book is divided into valuable in today’s managed-care environment. five sections and an appendix, each with emphasis on clinical information. Section IV includes normal laboratory values and interpretation of The tremendous success of the previous editions and the enthusiastic results of commonly ordered laboratory tests. By providing interpretation of comments from numerous colleagues have brought about several positive abnormal results, this section facilitates the diagnosis of medical disorders changes. Each section has been significantly expanded from prior editions, and further adds to the comprehensive, “one-stop” nature of our text. bringing the total number of medical topics covered in this book to more Section V focuses on preventive medicine. Information in this section than 1000. Nearly 500 new illustrations and tables have been added to the includes recommendations for the periodic health examination, screening edition to enhance recollection of clinically important facts. The expedited for major diseases and disorders, patient counseling, and immunization claims submission and reimbursement ICD-10CM codes have been added and chemoprophylaxis recommendations. to all the topics, along with existing ICD-9CM codes. Please note that the The Appendix has been divided into six major sections. Section I con- implementation of the ICD-10CM codes has been delayed until at least tains extensive information on complementary and alternative medicine 2016; therefore, for billing purposes please use the ICD-9CM codes until (CAM). With the material in this appendix, we hope to lessen the current the ICD-10CM codes are officially implemented. scarcity of exposure of allopathic and osteopathic physicians to the diver- Section I describes in detail more than 800 medical disorders. Twenty- sity of CAM therapies. Section II focuses on nutrition, with an emphasis on one new topics have been added to the 2016 edition. Each medical topic dietary supplements, vitamins, and minerals. Section III deals with diagno- in this section is arranged alphabetically, and the material in each topic is sis and treatment of acute poisoning. Section IV is a guide on impairment presented in outline format for ease of retrieval. Topics with an accompa- and disability evaluation. Section V, available online, contains an extensive nying algorithm in Section III are identified with an algorithm symbol (ALG). section on primary care procedures. Section VI contains several patient Similarly, if topics also have a Patient Teaching Guide (PTG) available online, teaching guides not linked to Section I topics. this has been noted. Throughout the text, key quick-access information is As clinicians, we all realize the importance of patient education and the consistently highlighted, clinical photographs are used to further illustrate need for clear communication with our patients. Toward that end, practi- selected medical conditions, and relevant ICD-9CM and ICD-10CM codes cal patient instruction sheets, organized alphabetically and covering the are listed. Most references focus on current peer-reviewed journal articles majority of the topics in this book, are available online and can be easily rather than outdated textbooks and old review articles. Evidence-based customized and printed from any computer. They represent a valuable medicine data have been added to relevant topics. addition to patient care and are useful for improving physician-patient Topics in Section I use the following structured approach: communication, patient satisfaction, and quality of care. 1. Basic Information (Definition, Synonyms, ICD-9CM and ICD-10CM Codes, I believe that we have produced a state-of-the-art information system Epidemiology & Demographics, Physical Findings & Clinical Presenta- with significant differences from existing texts. It contains five sections tion, Etiology) and patient education guides that could be sold separately based on their 2. Diagnosis (Differential Diagnosis, Workup, Laboratory Tests, Imaging content, yet are available under a single cover, offering the reader a tre- Studies) mendous value. I hope that the Clinical Advisor’s user-friendly approach, 3. Treatment (Nonpharmacologic Therapy, Acute General Rx, Chronic Rx, numerous unique features, and yearly updates will make this book a Disposition, Referral) valuable medical reference, not only to primary care physicians but also to 4. Pearls & Considerations (Comments, Suggested Readings) physicians in other specialties, medical students, and allied health profes- 5. Evidence-Based Data and References sionals. Section II includes the differential diagnosis, etiology, and classification of signs and symptoms. This section has been significantly expanded for Fred F. Ferri, M.D., F.A.C.P. the 2016 edition with the addition of 22 new topics. It is a practical section that allows the user investigating a physical complaint or abnormal labora- Note: Comments from readers are always appreciated and can be tory value to follow a “workup” leading to a diagnosis. The physician can forwarded directly to Dr. Ferri at [email protected]. then easily look up the presumptive diagnosis in Section I for the informa- tion specific to that illness. xxiv Preface xxv EVALUATION OF EVIDENCE SOURCES OF EVIDENCE Ferri’s Clinical Advisor evaluates all evidence based on a rating system Evidence is summarized principally from three critically evaluated, very published by the American Academy of Family Physicians. In order to indi- highly regarded sources: cate the strength of the supporting evidence, each summary statement is • Cochrane Systematic Reviews are respected throughout the world as accorded one of three levels: one of the most rigorous searches of medical journals for randomized LEVEL A controlled trials. They provide highly structured systematic reviews, with • Systematic reviews of randomized controlled trials, including meta- evidence included or excluded on the basis of explicit quality-related analyses criteria, and they often use meta-analyses to increase the power of the • Good-quality randomized controlled trials findings of numerous studies. LEVEL B • Clinical Evidence is produced by the BMJ Publishing Group. It provides • Good-quality nonrandomized clinical trials synopses of the best currently available evidence on the treatment and • Systematic reviews not in Level A prevention of many clinical conditions, based on searches and apprais- • Lower-quality randomized controlled trials not in Level A als of the available literature. • Other types of study: case-control studies, clinical cohort studies, cross- • The National Guideline Clearinghouse™ is a comprehensive data- sectional studies, retrospective studies, and uncontrolled studies base of evidence-based clinical practice guidelines and related docu- LEVEL C ments produced by the Agency for Healthcare Research and Quality in • Evidence-based consensus statements and expert guidelines partnership with the American Medical Association and the American Association of Health Plans. In addition, where evidence exists that has not yet been critically reviewed in one of the three sites above, the evidence is summarized briefly, categorized, and fully referenced. Guidelines are also sourced from government and professional bodies. Contents SECTION I Diseases and Disorders, 1 SECTION II Differential Diagnosis, 1323 SECTION III Clinical Algorithms, 1469 SECTION IV Laboratory Tests and Interpretation of Results, 1639 SECTION V Clinical Practice Guidelines, 1691 APPENDIX I Complementary and Alternative Medicine, 1761 APPENDIX II Nutrition, 1775 APPENDIX III Acute Poisoning, 1787 APPENDIX IV Impairment and Disability Issues, 1795 APPENDIX V Primary Care Procedures, available online APPENDIX VI Patient Teaching Guides, available online xxvii Detailed Contents SECTION I Diseases and Disorders Abdominal aortic aneurysm, 3 Amyotrophic lateral sclerosis, 106 Benign paroxysmal positional vertigo, 211 Abdominal compartment syndrome, 6 Anaerobic infections, 107 Benign prostatic hyperplasia, 214 Abruptio placentae, 8 Anal fissure, 108 Biceps tendonitis, 217 Abscess, breast, 10 Anaphylaxis, 109 Bipolar disorder, 219 Abscess, epidural, 11 Angina pectoris, 110 Bite wounds, 221 Abscess, liver, 12 Angioedema, 115 Bites and stings, arachnids, 223 Abscess, lung, 14 Ankle fracture, 117 Bites and stings, insect, 224 Abscess, pelvic, 16 Ankle sprain, 119 Bites, snake, 226 Abscess, perirectal, 17 Ankylosing spondylitis, 121 Bladder cancer, 229 Abscess, peritonsillar, 18 Anorectal fistula, 123 Blepharitis, 232 Abscess, renal, 19 Anorexia nervosa, 124 Body dysmorphic disorder, 233 Abscess, retropharyngeal, 20 Anoxic brain injury, 126 Bone tumor, primary malignant, 234 Absence seizures, 22 Antiphospholipid antibody syndrome, 128 Borderline personality disorder, 235 Abuse, child, 23 Anxiety (generalized anxiety disorder), 131 Botulism, 237 Abuse, drug, 26 Aortic dissection, 132 Brain abscess, 238 Abuse, elder, 29 Aortic regurgitation, 135 Brain metastases, 240 Acetaminophen poisoning, 31 Aortic stenosis, 137 Brain neoplasm, benign, 242 Achalasia, 32 Aplastic anemia, 139 Brain neoplasm, glioblastoma, 244 Achilles tendon rupture, 34 Appendicitis, acute, 141 Breast cancer, 246 Acne vulgaris, 35 Arrhythmogenic right ventricular dysplasia, Breech birth, 252 Acoustic neuroma, 37 143 Bronchiectasis, 253 Acquired immunodeficiency syndrome, 38 Asbestosis, 145 Brugada syndrome, 255 Actinic keratosis, 40 Ascariasis, 146 Bruxism, 258 Actinomycosis, 42 Ascites, 147 Budd-Chiari syndrome, 259 Acute bronchitis, 44 Aspergillosis, 149 Bulimia nervosa, 261 Acute colonic pseudo-obstruction (Ogilvie’s Aspiration pneumonia, 151 Bullous pemphigoid, 263 syndrome), 45 Asthma, 152 Burning mouth syndrome, 264 Acute coronary syndrome, 47 Astrocytoma, 162 Burns, 265 Acute fatty liver of pregnancy, 52 Ataxia, 164 Bursitis, 268 Acute kidney injury, 53 Atelectasis, 165 Calcium pyrophosphate dihydrate crystal Acute liver failure, 58 Atopic dermatitis, 166 deposition disease, 269 Acute lymphoblastic leukemia, 61 Atrial fibrillation, 167 Candidiasis, cutaneous, 271 Acute myelogenous leukemia, 64 Atrial flutter, 171 Candidiasis, invasive, 273 Acute pancreatitis, 69 Atrial myxoma, 173 Carbon monoxide poisoning, 275 Acute respiratory distress Atrial septal defect, 174 Carcinoid syndrome, 277 syndrome, 73 Attention deficit hyperactivity disorder, 177 Cardiac tamponade, 279 Acute stress disorder, 77 Autism spectrum disorder, 179 Cardiomyopathy, chemical-induced, 281 Acute tubular necrosis, 79 Autoimmune hemolytic anemia, 181 Cardiomyopathy, dilated, 283 Acute urinary retention (AUR), 80 Autoimmune hepatitis, 184 Cardiomyopathy, hypertrophic, 285 Adrenal insufficiency, 81 AV malformations, cerebral, 186 Cardiomyopathy, restrictive, 288 Alcoholic hepatitis, 83 Avascular necrosis, 188 Cardiorenal syndrome, 291 Alcoholism, 85 Babesiosis, 191 Carotid sinus syndrome, 293 Aldosteronism, 89 Bacterial meningitis, 193 Carotid stenosis, 295 Allergic rhinitis, 91 Bacterial pneumonia, 196 Carpal tunnel syndrome, 297 Alopecia, 92 Bacterial vaginosis, 199 Cataracts, 298 Alpha-1-antitrypsin deficiency, 94 Baker’s cyst, 200 Cat-scratch disease, 299 Alzheimer’s disease, 95 Balanitis, 201 Celiac disease, 300 Amaurosis fugax, 97 Barrett esophagus, 202 Cellulitis, 302 Amblyopia, 98 Basal cell carcinoma, 204 Cervical cancer, 304 Amebiasis, 99 Bedbug bite, 205 Cervical dysplasia, 305 Amenorrhea, 100 Behçet’s disease, 207 Cervical insufficiency, 308 Amnestic disorders, 104 Bell’s palsy, 209 Cervical polyps, 310 xxviii Detailed Contents xxix Cervicitis, 311 Diabetic polyneuropathy, 422 Frozen shoulder, 518 Charcot-Marie-Tooth disease, 312 Diabetic retinopathy, 425 Galactorrhea, 519 Charcot’s joint, 313 Diffuse idiopathic skeletal hyperostosis, Ganglia, 520 Chemotherapy-induced nausea and 427 Gastric cancer, 521 v omiting, 314 Discoid lupus, 429 Gastrinoma, 523 Chlamydia genital infections, 315 Disseminated intravascular coagulation, Gastritis, 525 Cholangitis, 316 430 Gastroenteritis, 526 Cholecystitis, 317 Dissociative disorders, 432 Gastroesophageal reflux disease, 528 Cholelithiasis, 318 Diverticular disease (diverticulosis, Gender dysphoria disorder and gender Chronic fatigue syndrome, 319 diverticulitis), 434 nonconformity, 530 Chronic inflammatory demyelinating Down syndrome, 435 Generalized tonic clonic seizures, 533 polyneuropathy (CIDP), 320 Dupuytren’s contracture, 436 Gestational diabetes mellitus (GDM), 534 Chronic kidney disease, 322 Dysfunctional uterine bleeding, 437 Giant cell arteritis, 536 Chronic lymphocytic leukemia, 326 Dysmenorrhea, 439 Giardiasis, 538 Chronic myelogenous leukemia, 328 Dyspareunia, 440 Gilbert’s syndrome, 539 Chronic obstructive pulmonary disease, 330 Dyspepsia, nonulcerative, 442 Gingivitis, 540 Chronic pain management, 335 Dysphagia, 443 Glaucoma, open-angle, 541 Chronic pancreatitis, 339 Dystonia, 445 Glaucoma, primary angle-closure, 542 Cirrhosis, 340 Echinococcosis, 447 Glenohumeral dislocation, 543 Claudication, 342 Eclampsia, 449 Glomerulonephritis, acute, 544 Clostridium difficile infection, 345 Ectopic pregnancy, 450 Glossitis, 547 Cluster headache, 347 Ehrlichiosis and anaplasmosis, 452 Gonococcal urethritis, 548 Cocaine overdose, 348 Ejaculation and orgasm disorders, 454 Gonorrhea, 549 Coccidioidomycosis, 350 Electrical and lightning injury, 456 Goodpasture’s syndrome, 551 Colorectal cancer, 352 Empyema, 458 Gout, 552 Compartment syndrome, 355 Encephalitis, acute viral, 459 Granuloma annulare, 554 Complex regional pain syndrome, 357 Encephalopathy, 461 Granulomatosis with polyangiitis Concussion, 358 Endocarditis, infective, 462 (Wegener’s granulomatosis), 555 Conduct disorder, 360 Endometrial cancer, 466 Graves’ disease, 557 Condyloma acuminatum, 361 Endometriosis, 468 Guillain-Barré syndrome, 559 Conjunctivitis, 362 Endometritis, 470 Gynecomastia, 561 Contact dermatitis, 364 Enuresis, 471 Hairy cell leukemia, 562 Contraception, 365 Epicondylitis, 473 Hand-foot-mouth disease, 563 Conversion disorder, 367 Epididymitis, 474 Health care-associated infections (HAIs), Cor pulmonale, 368 Epidural hematoma, 475 564 Corneal abrasion, 371 Epiglottitis, 477 Heart block, complete, 568 Corneal ulceration, 372 Episcleritis, 478 Heart block, second-degree, 570 Coronary artery disease, 373 Epistaxis, 479 Heart failure, 572 Costochondritis, 377 Epstein-Barr virus infection, 481 Heat exhaustion and heat stroke, 579 Craniopharyngioma, 378 Erectile dysfunction, 482 Helicobacter pylori infection, 581 Crohn’s disease, 379 Erysipelas, 484 HELLP syndrome, 583 Cryoglobulinemia, 381 Erythema multiforme, 485 Hemochromatosis, 585 Cryptococcosis, 382 Erythema nodosum, 486 Hemolytic-uremic syndrome, 587 Cryptosporidium infection, 383 Esophageal tumors, 487 Hemophilia, 589 Cubital tunnel syndrome, 384 Esophageal varices, 490 Hemorrhoids, 591 Cushing’s disease and syndrome, 355 Essential tremor, 493 Henoch-Schönlein purpura, 592 Cystic fibrosis, 387 Failure to thrive (pediatric), 494 Heparin-Induced Thrombocytopenia, 594 Cysticercosis, 389 Falls in the elderly, 496 Hepatic encephalopathy, 596 Cytomegalovirus infection, 391 Familial adenomatous polyposis and Hepatitis A, 598 Deep vein thrombosis, 392 Gardner’s syndrome, 498 Hepatitis B, 600 Delayed puberty, 395 Febrile seizures, 500 Hepatitis C, 603 Delirium, 398 Fetal alcohol syndrome, 501 Hepatocellular carcinoma, 605 Delirium tremens, 400 Fever of undetermined origin, 503 Hepatopulmonary syndrome, 608 Delusional parasitosis, 401 Fibrocystic breast disease, 505 Hepatorenal syndrome, 609 Dementia with Lewy bodies, 402 Fibromyalgia, 506 Hereditary neuropathy, 611 Dependent personality disorder, 404 Fifth Disease (Parvovirus B19 infection), Herpes simplex, 613 Depression, major, 405 508 Herpes zoster, 615 De Quervain’s tenosynovitis, 407 Folliculitis, 510 Hiatal hernia, 617 Dermatitis herpetiformis, 408 Food allergies, 511 Hidradenitis suppurativa, 619 Diabetes mellitus, 410 Food poisoning, bacterial, 513 High-altitude sickness, 621 Diabetic foot, 417 Friedreich’s ataxia, 515 Hip fracture, 623 Diabetic ketoacidosis, 419 Frostbite, 516 Hirsutism, 625 Detailed Contents xxx Histoplasmosis, 628 Lichen sclerosus, 743 Myocardial infarction, 843 HIV cognitive dysfunction, 630 Lichen simplex chronicus, 744 Myocarditis, 850 Hodgkin’s lymphoma, 631 Listeriosis, 745 Myoclonus, 853 Hookworm, 635 Long QT syndrome, 746 Myofascial pain syndrome, 854 Hordeolum (stye), 636 Lumbar disc syndrome, 749 Myopathies, idiopathic inflammatory, 856 Horner’s syndrome, 637 Lung neoplasms, primary, 751 Myxedema coma, 859 Hot flashes, 638 Lyme disease, 755 Narcolepsy, 860 Human immunodeficiency virus, 639 Lymphangitis, 756 Necrotizing fasciitis, 862 Huntington’s disease, 646 Lymphedema, 757 Nephroblastoma, 864 Hydrocele, 647 Lynch syndrome, 759 Nephrogenic systemic fibrosis, 865 Hydrocephalus, normal pressure, 648 Macular degeneration, 760 Nephrotic syndrome, 866 Hydronephrosis, 649 Malaria, 761 Neuroblastoma, 869 Hypercholesterolemia, 651 Malignant hyperthermia, 765 Neurofibromatosis, 871 Hypercoagulable state, 654 Mallory-Weiss tear, 767 Neuroleptic malignant syndrome, 873 Hyperemesis gravidarum, 657 Marfan’s syndrome, 768 Neuropathic pain, 874 Hyperlipoproteinemia, primary, 658 Mastitis, 770 Nonalcoholic fatty liver disease, 877 Hyperosmolar hyperglycemic syndrome, Mastodynia, 772 Nongonococcal urethritis, 878 660 Mastoiditis, 773 Non-Hodgkin lymphoma, 879 Hyperparathyroidism, 661 Meckel diverticulum, 774 Obesity, 882 Hypersensitivity pneumonitis, 663 Mediastinitis, 775 Obsessive-compulsive disorder (OCD), 886 Hypersplenism, 665 Meigs’ syndrome, 776 Ocular foreign body, 887 Hypertension, 666 Melanoma, 777 Onychomycosis, 888 Hyperthyroidism, 672 Ménière’s disease, 780 Opioid dependence, 890 Hypertrophic osteoarthropathy, 674 Meningioma, 781 Optic atrophy, 893 Hyperuricemia, 676 Menopause, 783 Optic neuritis, 894 Hypoaldosteronism, 677 Menorrhagia, 785 Oral cancer, 895 Hypogonadism, male, 678 Meralgia paresthetica, 786 Oral hairy leukoplakia, 897 Hypoparathyroidism, 681 Mesenteric ischemia, acute, 788 Orchitis, 898 Hypopituitarism, 683 Mesenteric venous thrombosis, 790 Orthostatic hypotension, 899 Hypothermia, 686 Mesothelioma, malignant, 791 Osgood-Schlatter disease, 901 Hypothyroidism, 688 Metabolic syndrome, 793 Osteoarthritis, 902 Idiopathic pulmonary fibrosis, 689 Methanol and ethylene glycol poisoning, 795 Osteochondritis dissecans, 904 IgA nephropathy, 691 Methicillin-resistant staphylococcus aureus Osteomyelitis, 905 Illness anxiety disorder, 693 (MRSA), 797 Osteoporosis, 907 Immune thrombocytopenic purpura, 694 Microscopic polyangiitis, 798 Otitis externa, 910 Impetigo, 696 Microsporidiosis, 800 Otitis media, 912 Inclusion body myositis, 697 Migraine headache, 801 Ovarian cancer, 914 Incontinence, bowel, elderly patient, 698 Mild cognitive impairment (MCI), 803 Ovarian neoplasm, benign, 916 Incontinence, urinary, 699 Mitral regurgitation, 804 Paget’s disease of bone, 917 Infertility, 701 Mitral stenosis, 807 Paget’s disease of the breast, 918 Inflammatory anemia, 703 Mitral valve prolapse, 810 Pancreatic cancer, (exocrine), 919 Influenza, 705 Mixed connective tissue disease, 812 Panic disorder, with or without Insomnia, 708 Molar pregnancy, 813 a goraphobia, 921 Intermittent explosive disorder, 711 Molluscum contagiosum, 815 Panniculitis, 923 Interstitial cystitis, 712 Monoclonal gammopathy of undetermined Paraneoplastic syndromes, 925 Interstitial lung disease, 714 significance (MGUS), 816 Paraphilic disorders, 927 Interstitial nephritis, 718 Mononucleosis, 818 Parkinson’s disease, 929 Intraventricular conduction delay, 720 Morton neuroma, 819 Paronychia, 931 Iron deficiency anemia, 721 Motion sickness, 821 Partial seizures, 932 Irritable bowel syndrome, 723 Mucormycosis, 822 Patellofemoral pain syndrome, 933 Jaundice in the adult patient, 725 Multidrug-resistant gram-negative rods Patent ductus arteriosus, 934 Juvenile idiopathic arthritis, 728 (MRG-GNRs), 823 Pediculosis, 936 Kaposi’s sarcoma, 730 Multifocal atrial tachycardia, 824 Pelvic inflammatory disease, 937 Kawasaki disease, 731 Multiple myeloma, 825 Pelvic organ prolapse (uterine prolapse), Keloid, 733 Multiple sclerosis, 828 939 Labyrinthitis, 735 Mumps, 830 Pemphigus vulgaris, 941 Lactose intolerance, 736 Muscular dystrophy, 832 Peptic ulcer disease, 943 Laryngeal carcinoma, 737 Mushroom poisoning, 834 Pericarditis, 945 Laryngotracheobronchitis, 738 Myasthenia gravis, 835 Peripheral arterial disease, 948 Lead poisoning, 740 Mycoplasma pneumonia, 836 Peritonitis, secondary, 951 Legg-Calvé-Perthes disease, 741 Mycosis fungoides, 838 Pernicious anemia, 952 Lichen planus, 742 Myelodysplastic syndrome, 840 Pertussis, 954
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