UvA-DARE (Digital Academic Repository) Exposure to nickel and palladium from dental appliances Ventura Da Cruz Rodrigues Milheiro, A.M. Publication date 2015 Document Version Final published version Link to publication Citation for published version (APA): Ventura Da Cruz Rodrigues Milheiro, A. M. (2015). Exposure to nickel and palladium from dental appliances. [Thesis, fully internal, Universiteit van Amsterdam]. General rights It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: https://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl) Download date:20 Jan 2023 Exposure to nickel and palladium from dental appliances Ana Maria Ventura da Cruz Rodrigues Milheiro Cover: Ana Milheiro, photography / Filipe Álvaro, design Printed by: GVO printers & designers B.V. | Ponsen & Looijen Copyright: © A. Milheiro All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, mechanically, by photocopy, by recording or otherwise, without permission of the author. Exposure to nickel and palladium from dental appliances ACADEMISCH PROEFSCHRIFT Ter verkrijging van de graad van doctor aan de Universiteit van Amsterdam op gezag van de Rector Magnificus prof. dr. D.C. van den Boom ten overstaan van een door het college voor promoties ingestelde commissie, in het openbaar te verdedigen in de Aula der Universiteit op vrijdag 27 november 2015, te 11:00 uur door Ana Maria Ventura da Cruz Rodrigues Milheiro geboren te Coimbra, Portugal Promotiecommissie Promotor Prof. dr. A.J. Feilzer, Universiteit van Amsterdam en Vrije Universiteit Amsterdam Co-promotor Dr. C.J. Kleverlaan, Universiteit van Amsterdam Overige leden Prof. dr. M. Özcan, Rijksuniversiteit Groningen, Universität Zurich Prof. dr. F.R. Rozema, Universiteit van Amsterdam Prof. dr. S. Gibbs, Vrije Universiteit Amsterdam Prof. dr. F.J.M. Roeters, Universiteit van Amsterdam Prof. dr. F. Lobbezoo, Universiteit van Amsterdam Prof. dr. T. Rustemeyer, Vrije Universiteit Amsterdam Faculteit der Tandheelkunde “Not all those who wander are lost” JRR Tolkien To my family This thesis was supported by ACTA Research Institute as well as MOVE research institute and prepared at the Department of Dental Materials Science of the Academic Center for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University, the Netherlands. CONTENTS Chapter 1 Introduction – A review of the literature 9 RELEASE OF METAL IONS IN VITRO Chapter 2 Nickel release from orthodontic retention wires – mechanical loading 45 and pH Chapter 3 Influence of shape and finishing on the corrosion of palladium-based 57 dental alloys A SIMPLIFIED BIOLOGIC APPROACH Chapter 4 In vitro cytotoxicity of metallic ions released from dental alloys 69 Chapter 5 Metal release and cytotoxicity of orthodontic retention wires 83 ON THE WAY TO A METAL-FREE ALTERNATIVE Chapter 6 In vitro debonding of Orthodontic Retainers analyzed with Finite 95 Element Analysis Discussion, Summary and Conclusions 109 Discussie, Samenvatting en Conclusies 113 Acknowledgements 119 About the author 125
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