Table Of Content

AUTHOR INDEX Adelman, R.C., 1 Fleming, J.E., 511 Luk, G.D., 45 Adler-Kunin, S., 357 Fligiel, S.E.G., 45 Aiello, V.R., 487 Fourtanier, A., 375 Majumdar, A.P.N., 45, 57 Akiyama, J., 29 Makinodan, T., 281 Allen, R.G., 515 Gibson, D.C., 1 Massie, H.R., 487 Allsopp, R., 385 Goonewardene, I.M., 269 Matour, D., 269 Aminoff, D., 315, 327 Grindeland, R.E., 257 Matsuo, M., 525 Armatis, P., 541 Gutowski, K.A., 315 McDougall, S., 281 Astier, H., 347 Miller, S., 97 Hahn, T.J., 281 Monk, T.H., 233 Bakala, H., 573 Hammel, I., 89 Morioka, S., 397 Barringer, D.L., 65 Hart, R., 97 Moriyama, K., 397 Bensch, K.G., 511 Hart, R.W., 453 Moshier, J.A., 45 Beregi, E., 601 Hashimoto, M., 397 Murasko, D.M., 269 Berg, H. van den, 589 Hatfield, J.S., 45 Bode, W., 589 Hayflick, L., 523 Nelson, B.J., 269 Bodner, L., 89, 357 Hazzard, D.G., 411 Nelson, G.A., 299 Boyer, B., 375 Heller, D.A., 467 Noble, R.C., 601 Bruce, S.A., 3, 17 Heller, K.E., 479 Bungo, M.W., 163 Higgins, K.A., 467 Ogden, L.L., 327 Bufiag, R.D., 65 Hirsch, H.R., 549 Ohara, T., 441 Busbee, D., 97 Honda, M., 397 Ohoka, M., 397 Busbee, D.L., 453 Horster, F.A., 347 Omann, G.M., 327 Hudson, J.L., 315 Ooka, H., 525 Carlson, J.C., 385 Hughes-Fulford, M., 247 Charles, J.B., 163 Hymer, W.C., 257 Parker, R.F., 467 Chiasera, A.J., 217 Pastoris, O., 77 Chimovitz, N., 89 lida-Klein, Akiko, 281 Penzes, L., 601 Cristofalo, V.J., 137 Ishinaga, Y., 397 Perichon, M., 573 Criswell-Hudak, B.S., 289 Izsak, J., 601 Porth, C.J.M., 141 Czeisler, C.A., 217 Johnson, T.E., 299 Rangan, S.R.S., 541 Danon, D., 357 Ray, E.K., 123 Dayan, D., 89 Kaji, K., 525 Roberts, B.E., 495 Deamond, S.F., 17 Kan, S., 365 Rolfes-Curl, A., 327 Dean, W., 615, 616, 618 Kawashima, S., 365 Rossum, J.P. van, 37 Devi, S.A., 365 Kaye, D., 269 Dossena, M., 77 Kern, P., 375 Saito, K., 29 Dubick, M.A., 57 Kiebzak, G.M., 171 Schaeverbeke, J., 573 Duffy, J.F., 217 Knyszynski, A., 357 Schamhart, D.H.J.,3 7 Kondo, H., 525 Schneider, V., 189 Ebbesen, P., 479 Kranz, D., 601 Schubert, K., 601 Edgerton, E.A., 45 Kyriazis, M., 569 Schultheis, L., 203 Schultheiss, H., 347 Fang, M., 281 Labat-Robert, J., 375 Sestini, E. A., 385 Finch, C.E., 411 LeBlanc, A., 189 Sheehy, M.R.J., 495 X AUTHOR INDEX Shibata, Y., 525 Sulzman, F.M., 131 Villadsen, J.A., 479 Shindo, Y., 29 Szabolcs, I., 347 Shumway, M.E., 487 Warner, H.R., 411 Smith, J.J., 141 Takase, Y., 29 Whitney, S.J.P., 487 Sohal, R.S., 515 Tasaki, Y., 441, 525 Williams, T.F., 121 Sprott, R.L., 135, 139, 169, Tilley, R.D., 97, 453 Witten, M., 549 215, 245, 267, 297 Utakoji, T., 525 Srivastava, V.K., 97, 453 Yamaguchi, D.T., 281 Sternick, S.M., 487 Yamamoto, K., 441, 525 Stout, J.T., 467 Vercesi, L., 77 Yamamoto, M., 441 Sudey, I., 573 Villadsen, H.D., 479 Yamazaki, Y., 29 KEYWORD INDEX abnormal proteins, 569 cholinergic blockade, 65 acetyl LDL receptor, 397 circadian rhythms, 233 age, 233, 541 human, 217 age determination, 495 cold tolerance, 601 age-related changes, 441, 525, 573 collagen(s), 3, 375 aging, 3, 45, 57, 65, 77, 97, 123, 171, collagen denaturation, 467 203, 217, 247, 269, 299, 365, conjugated Schiff base, 495 375, 397, 453, 487, 589, 601 contaminating polar pteridines, 495 and circulation, 141 continuous normobaric hypoxia, 77 correlations of space effects and, 123 Crustacea, 495 aging erythrocytes, 315, 327 culture, 365, 397 amylase, 57 ascorbic acid, 487 dermis, 3, 17 autofluorescence, 89 development, 299 autoimmune antibodies, 315, 327 dietary restriction, 89, 453 differential rates of change, 467 B-adrenergic blockade, 65 differentiation, 3 B-lymphocytes, 541 disposable soma theory, 569 baroreflexes, 65 DNA polymerase, 97, 453 bed rest, 189 DNA repair, 299 biokinetics, 589 dominance, 479 biomechanics, 171 Drosophila, 385, 487 biopsy, 17 biosynthesis, 375 EBV, 541 blood, 541 echocardiography, 163 blood pressure, 65 endothelial cells, 397 bone cells, 171 enzyme activities, 77 bone control system, 203 erythrocytes, aging, 315, 327 bone loss, 171 erythrocytes, senescent, 327 bone matrix, 171 exercise, 189 bone mechanical strain, 203 extracellular matrix, 3, 375 bone mineral, 171 density, 189 feeding, 479 bone strength, 171 fiber variability, 467 fibroblast, 3 calorie, 97 fibronectin, 375 cardiovascular physiology, 163 fish, 495 catalase, 29 flow cytometry, 315, 327 cell growth, 247 fluorescent material, 365 cell loss, 281 free radicals, 299, 385, 569 cell size, 315, 327 frequency, 541 cellular identification, 441 cellular immune response, 289 gastric mucosal injury, 45 central venous pressure (CVP), 163 gastrin, 57 cerebral cortical cell, 365 genetic variation, 269 chaos theory, 569 genetics, 299 XII KEYWORD INDEX geriatric conditions, 37 muscular metabolism, 77 glomerular cell membrane, 573 mutants, 299 glutathione peroxidase, 29 glycosaminoglycans, 573 nematodes, 299 gravity, 299 nutrition, 281 growth hormone, 257 bioassayable, 257 ODC gene expression, 45 immunoassayable, 257 old age, 347 ornithine decarboxylase, 45 headward fluid shift, 163 orthostatic hypotension, 141 heart rate, 65 orthostatic tolerance, 163 hepatic tissue, 453 osteoporosis, 171, 203 homeostasis, 171 oxidation-reduction potential, 37 human, 233, 315, 327 oxidative stress, 299 human diploid cell strains, 441 new, 525 pancreas, 57 human skin fibroblast, 29 parasympathetic, 65 perioral muscles, 89 immobilization, 189 pharmacological treatment, 77 immunological aging, 569 phase shift, 233 immunopotentiation, 281 phospholipase A,, 385 immunoreactive ODC, 45 physiological adaptation, 131 immunosenescence, 281 pituitary, 257 inhibition of TSH by T3, 347 postural changes, 141 insects, 495 proteoglycans, 573 interleukin-2, 269 pyridoxal, 589 isozyme polymorphism, 441 pyridoxal-5’-phosphate, 589 kidney, 573 qualitative changes, 281 lectins, 315, 327 radiation, 299 licking, 357 radiobiology, 299 life-history traits, 299 ranking, 479 life span, 385, 479, 487 rat(s), 57, 347 light, 217 aging, 257 lipid peroxidation, 385 conscious, 65 lipid pigments, 89 spaceflown, 257 lipofuscin, 89, 365 tail-suspended, 257 lipofuscin solvent extraction, 495 rat aorta, 397 longevity, 299 rat tongue muscle, 89 lower body negative pressure, 141 remodeling of bone, 171 lymphocyte activity, 289 salivary glands, 357 melatonin, 217 Sarcophaga bullata, 495 metabolism, 589 senescence, 3 mice, 357, 453, 601 senescent erythrocytes, 327 DBA/2 male, 479 sialidase treatment, 315, 327 skin, 375 skeletal muscle pump, 141 microgravity, 123, 131, 247, 257, 281 skin, 357 mitogen-induced lymphoproliferation, 269 mouse, 357 modulation, 281 sleep, 217, 233 molecular aging, 569 space, 299 mRNA, 57 space adaptation, 247 KEYWORD INDEX spaceflight, 123, 163, 189, 203, 247, 257, 269 tendon group differences, 467 human response to, 131 thoracic blood volume, 141 manned, 217 thyroid, 601 space immunity, 289 thyroid hormones, 601 space life sciences, 123, 131 TIG-7, 525 space medicine, 131 comparison with TIG-1, 525 Space Shuttle, 163 tissue grafting, 281 Space Station Freedom, 131 TRH-induced TSH release, 347 spontaneous cells lines, 541 trypsin, 57 storage excretion, 495 subordination, 479 upright posture, 141 superfused pituitary fragments, 347 superoxide dismutase, 29, 385 vitamin B-6, 589 survival, 479 vitamin C, 487 susceptibility to leukemia virus, 479 vitamin E, 365 sympathetic, 65 Syrian hamster, 3, 17 weightlessness, 141, 163 wound healing, 17, 357 T cells, 281