VViirrggiinniiaa CCoommmmoonnwweeaalltthh UUnniivveerrssiittyy VVCCUU SScchhoollaarrss CCoommppaassss Theses and Dissertations Graduate School 2015 EEvvaalluuaattiioonn aanndd CCoommppaarriissoonn ooff TThheeoorreettiiccaall MMooddeellss’’ AAbbiilliittiieess ttoo EExxppllaaiinn aanndd PPrreeddiicctt CCoolloorreeccttaall CCaanncceerr SSccrreeeenniinngg BBeehhaavviioorrss Anthony J. Molisani Virginia Commonwealth University Follow this and additional works at: https://scholarscompass.vcu.edu/etd Part of the Public Health Commons, and the Social and Behavioral Sciences Commons © The Author DDoowwnnllooaaddeedd ffrroomm https://scholarscompass.vcu.edu/etd/4017 This Dissertation is brought to you for free and open access by the Graduate School at VCU Scholars Compass. It has been accepted for inclusion in Theses and Dissertations by an authorized administrator of VCU Scholars Compass. For more information, please contact [email protected]. ©Anthony J. Molisani 2015 All Rights Reserved Evaluation and Comparison of Theoretical Models’ Abilities to Explain and Predict Colorectal Cancer Screening Behaviors A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University. by Anthony Molisani, Bachelor of Science, University of Rochester, 2008 Master of Public Health, Drexel University, 2010 Director: Robin K Matsuyama, Ph. D., Associate Professor, Department of Health Behavior and Policy Virginia Commonwealth University Richmond, Virginia November, 2015 Acknowledgement The author wishes to thank several people for guiding and supporting him throughout his work. I’d like to thank Robin Matsuyama, Ph.D. for her dedication and immense support in advising me throughout my time at Virginia Commonwealth University. Thank you to my committee: Levent Dumenci, Ph.D., Kellie Carlyle, Ph.D., M.P.H., Robert Perera, Ph.D., and Kathleen Ingram, Ph.D. Each of you has provided unique perspective and guidance that has greatly enriched my work and research approach. Thank you to the Department of Health Behavior and Policy, including Laura Siminoff, Ph.D. Completion of this program would not have been possible without the collective and individual support from all within the department. Also, I’d like to thank my family: Rick, Lynne, Michael, and Joseph Molisani for being the foundation of my values and talents. Thank you to Emily Brown for her unyielding strength and love. Lastly, thank you to Luca, my best friend that has been unconditionally by my side throughout my entire graduate career. Finally, I’d like to dedicate this work to the memory of Lisa Ulmer, Sc.D., M.S.W. Your faith and vision set me on this path for which I am truly grateful. ii Table of Contents List of Tables ................................................................................................................................ vii List of Figures .............................................................................................................................. viii Abstract .......................................................................................................................................... xi Introduction ................................................................................................................................... 13 Background ................................................................................................................................... 14 Colorectal Cancer...................................................................................................................... 14 Staging of Colon and Rectum Cancers. ................................................................................ 14 Colorectal cancer rates and trends. ....................................................................................... 17 Screening Methods, Guidelines, and Rates............................................................................... 20 Types of colorectal cancer screening. ................................................................................... 20 Colorectal Screening Recommendations and Guidelines ..................................................... 22 Screening Rates ..................................................................................................................... 23 Screening Behaviors and Cues to Action.................................................................................. 24 Conceptual Framework ............................................................................................................. 26 Behavioral Theory .................................................................................................................... 27 Health Belief Model. ............................................................................................................. 30 Theory of Reasoned Action. ................................................................................................. 36 Theory of Planned Behavior. ................................................................................................ 40 iii Attribution Theory. ............................................................................................................... 43 Theory Application in Colorectal Cancer Screening ................................................................ 45 Behavioral Value. ................................................................................................................. 45 Outcome Value. .................................................................................................................... 50 Summary. .............................................................................................................................. 51 Methods......................................................................................................................................... 53 Overview ................................................................................................................................... 53 Theory Testing .......................................................................................................................... 53 Study Design ............................................................................................................................. 57 Participant Criteria. ............................................................................................................... 57 Survey Administration. ......................................................................................................... 58 Variables and Measures ............................................................................................................ 60 Theory of Reasoned Action/Theory of Planned Behavior. ................................................... 60 Attribution Theory. ............................................................................................................... 61 Health Belief Model. ............................................................................................................. 62 Colorectal Cancer Screening Behavioral Intention............................................................... 63 Previous Colorectal Cancer Screening Behavior. ................................................................. 63 Participant Characteristics. ................................................................................................... 63 Analysis..................................................................................................................................... 63 Behavioral Theory Model Testing. ....................................................................................... 64 Theoretical Model Comparison. ........................................................................................... 75 Sample Size and Power Consideration ..................................................................................... 75 Methodological Considerations ................................................................................................ 78 Meeting Study Goals................................................................................................................. 79 Results ........................................................................................................................................... 80 iv Descriptive Statistics ................................................................................................................. 80 Sociodemographics. .............................................................................................................. 80 Health Status. ........................................................................................................................ 81 Previous Colorectal Cancer Screening Behavior. ................................................................. 82 Colorectal Cancer Screening Behavioral Intentions. ............................................................ 84 Colorectal Cancer Screening Modality Preference. .............................................................. 86 Confirmatory Factor Analyses .................................................................................................. 87 Health Belief Model. ............................................................................................................. 87 Theory of Reasoned Action. ................................................................................................. 92 Theory of Planned Behavior. ................................................................................................ 94 Attribution Theory. ............................................................................................................... 96 Theoretical Structural Equation Models ................................................................................... 98 Health Belief Model. ........................................................................................................... 100 Theory of Reasoned Action. ............................................................................................... 106 Theory of Planned Behavior. .............................................................................................. 110 Attribution Theory. ............................................................................................................. 114 Discussion ................................................................................................................................... 119 Model Analyses ...................................................................................................................... 119 Confirmatory Factor Analyses. ........................................................................................... 119 Whole Theoretical Models. ................................................................................................. 124 Theoretical Models Comparison. ........................................................................................ 141 Theoretical Application .......................................................................................................... 144 Theory Evaluation. .............................................................................................................. 144 Theory Integration. ............................................................................................................. 148 Colorectal Cancer Screening Practical Application ................................................................ 152 v Limitations .............................................................................................................................. 157 Design Limitations. ............................................................................................................. 157 Execution Limitations. ........................................................................................................ 158 Theoretical Limitations. ...................................................................................................... 159 Future Approach ..................................................................................................................... 160 Summary ..................................................................................................................................... 164 References ................................................................................................................................... 166 Appendix A – Survey Instrument ............................................................................................... 179 vi List of Tables 1. Comparison of Summary Staging and Extent of Disease Codes for Colon Cancer as Classified by the Surveillance, Epidemiology and End Results (SEER) Program (National Cancer Institute, 2009)..…………………...................................................... ....16 2. Stages of Colorectal Cancer (National Cancer Institute, 2006)……................................... ....17 3. Sociodemographics……………………………………………………………………….. ....81 4. Study sample health status…..…..…..…..…....................................................................... ....82 5. General CRC screening adherence…...……...…………………………………………… ....83 6. Previous CRC screening behavior by modality…………………………………………... ....84 7. CRC screening behavioral intentions…………………………………………………….......85 8. Confirmatory factor analyses models information……………………………………...... ....99 9. Structural equation models information………………………………………………….....100 vii List of Figures 1. Conceptual Framework for Colorectal Cancer Screening with Examples of Each Value Type…………………………………………………………………………………… 27 2. Conceptual Model of Health Belief Model (Rosenstock, 1974b)………………………… 32 3. Conceptual Model of the Theory of Reasoned Action (Madden et al., 1992)…………… 40 4. Conceptual Model of the Theory of Planned Behavior (Ajzen, 1991)…………………… 41 5. Dimensions of Attribution Theory by perceived Locus of Control and Causal Stability… 45 6. Illustrative example of a linear regression model of a 4-construct theory……………….. 54 7. Structural Equation Model of a 4-construct theory……………………………………….. 56 8. Attitudes TRA/TPB construct………………………………………….............................. 67 9. Subjective norms TRA/TPB construct……………………………………......................... 68 10. Perceived behavioral control TPB construct……………………………………………… 68 11. Internal locus of control AT construct………………………………................................. 69 12. Stability AT construct……………………………………………….................................. 69 13. Perceived susceptibility HBM construct………………………………….......................... 70 viii
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