Table Of Content

European Journal of Pharmacology — Molecular Pharmacology Section, 226 (1992) 383-385 © 1992 Elsevier Science Publishers B.V. All rights reserved 0922-/4921 /$0056.0 0 Author index Abdel-Latif, A.A., Yousufzai, S.Y.K., De, S. and Tachado, S.D. Duncia, J.V., see Reilly, T.M. (226) 179 Carbachol stimulates adenylate cyclase and phospholipase C and Durell, S.R., see Cruciani, R.A. (226) 287 muscle contraction-relaxation in a reciprocal manner in dog iris sphincter smooth muscle (226) 351 Ericson, H. and Ross, S.B. Acuna Castroviejo, D., Del Aguila, C.M., Fernandez, B., Gomar, Subchronic treatment of rats with remoxipride fails to modify 7 M.D. and Castillo, J.L. binding sites in the brain (226) 157 Characterization of ouabain high-affinity binding to rat cerebral Errol, C., see Hall, A.S. (226) 253 cortex. Modulation by melatonin (226) 59 Esbenshade, T.A., see Han, C. (226) 141 Aktories, K., see Koch, G. (226) 87 Aleppo, G., see Sortino, M.A. (226) 273 Fauq, A.H., see Reynolds, I.J. (226) 53 Allgaier, C., see Jackisch, R. (226) 245 Fernandez, B., see Acufia Castroviejo, D. (226) 59 Forn, J., see Marmol, F. (226) 93 Ball, S.G., see Hall, A.S. (226) 253 Friedman, E., see Undie, A.S. (226) 297 Balmforth, A.J., see Hall, A.S. (226) 253 Barker, J.L., see Cruciani, R.A. (226) 287 Gacel, G.A., see Cheng, J. (226) 15 Bernad, N., see Galas, M.C. (226) 35 Galas, M.C., Bernad, N. and Martinez, J. Boddeke, H.W.G.M., see Pombo-Villar, E. (226) 317 Pharmacological studies on CCK, receptors in guinea pig synap- Boeynaems, J.-M., see Coquette, A. (226) 1 toneurosomes (226) 35 Bormann, J., see Miller, W.E.G. (226) 209 Gallager, D.W., see Primus, R.J. (226) 21 Brabec, V., see Vrana, O. (226) 5 Gerlach, M., Riederer, P. and Youdim, M.B.H. Branch, R.A., see Sabra, R. (226) 79 The molecular pharmacology of L-deprenyl (226) 97 Bryson, S.E., see Hall, A.S. (226) 253 Glenert, U. Buckland, P.R., see O’Donovan, M.C. (226) 335 Effects of chronic anethole trithione and amitriptyline treatment Budohoski, L., see Challiss, R.A.J. (226) 121 on rat parotid gland signalling (226) 43 Gomar, M.D., see Acufia Castroviejo, D. (226) 59 Canonico, P.L., see Sortino, M.A. (226) 273 Graham, D., Darles, G. and Langer, S.Z. Carbonell, L., see Marmol, F. (226) 93 The neuroprotective properties of ifenprodil, a novel NMDA Castillo, J.L., see Acuna Castroviejo, D. (226) 59 receptor antagonist, in neuronal cell culture toxicity studies (226) Challiss, R.A.J., Richards, S.J. and Budohoski, L. 373 Characterization of the adenosine receptor modulating insulin Greene, C., Schwindt, P. and Crill, W. action in rat skeletal muscle (226) 121 Metabotropic receptor mediated afterdepolarization in neocorti- Cheng, J., Roques, B.P., Gacel, G.A., Huang, E. and Pasternak, cal neurons (226) 279 G.W. GroB, R., see Theis, J.G.W. (226) 149 _ K3 Opiate receptor binding in the mouse and rat (226) 15 Guy, H.R., see Cruciani, R.A. (226) 287 Christ, D.D., see Reilly, T.M. (226) 179 Chun, M., see Sun, L. (226) 367 Habermann, B., see Koch, G. (226) 87 Coquette, A., Boeynaems, J.-M. and Vray, B. Hall, A.S., Errol, C., Bryson, S.E., Ball, S.G. and Balmforth, A.J. Eicosanoids modulate CR1- and Fc-dependent bacterial phagocy- Thiol group identification at or near the agonist binding site of tosis (226) 1 the vascular dopamine receptor (226) 253 Crill, W., see Greene, C. (226) 279 Hammerland, L.G., Olivera, B.M. and Yoshikami, D. Cruciani, R.A., Barker, J.L., Durell, S.R., Raghunathan, G., Guy, Conantokin-G selectively inhibits N-methyl-D-aspartate-induced H.R., Zasloff, M. and Stanley, E.F. currents in Xenopus oocytes injected with mouse brain mRNA Magainin 2, a natural antibiotic from frog skin, forms ion chan- (226) 239 nels in lipid bilayer membranes (226) 287 Han, C., Esbenshade, T.A. and Minneman, K.P. Cuffi, M.L., see Marmol, F. (226) 93 Subtypes of a,-adrenoceptors in DDT, MF-2 and BC3H-1 clonal cell lines (226) 141 Dapper, J., see Miller, W.E.G. (226) 209 Hartmann, M. and Schrader, J. Darles, G., see Graham, D. (226) 373 Protein kinase C phosphorylates a 15 kDa protein but not phos- Davies, M.F., see Maguire, P.A. (226) 233 pholamban in intact rat cardiac myocytes (226) 225 Davis, J.M., see Pandey, G.N. (226) 303 Hertting, G., see Jackisch, R. (226) 245 De, S., see Abdel-Latif, A.A. (226) 351 Hill, S.J., see Iredale, P.A. (226) 163 Del Aguila, C.M., see Acuna Castroviejo, D. (226) 59 Holmes, P.V. and Drugan, R.C. Dellweg, H., see Theis, J.G.W. (226) 149 Angiotensin II rapidly modulates the renal peripheral benzodi- DeLuca, A.W., see Valliere, J.E. (226) 191 azepine receptor (226) 189 De Weille, J.R., see Szewczyk, A. (226) 175 Honscha, W., Ottallah, M., Schenk, A., Schuh, K. and Petzinger, E. Drugan, R.C., see Holmes, P.V. (226) 189 Separation and purification by two-dimensional gel electrophore- 384 sis of a 52-54 kDa bumetanide binding protein from rat liver Nahorski, S.R., see Safrany, S.T. (226) 265 plasma membranes (226) 215 Nakajima, M., see Tsujino, T. (226) 69 Hsieh, S.-T., see Tsujino, T. (226) 69 Neuhaus, R. and Reber, B.F.X. Huang, E., see Cheng, J. (226) 15 Inhibition of membrane currents and rises of intracellular Ca?* Huang, H.Y., see Jackisch, R. (226) 245 in PC12 cells by CGS 9343B, a calmodulin inhibitor (226) 183 Newman, M.E. IJzerman, A.P., see Van der Bent, A. (226) 327 Serotonin inhibits adenylate cyclase in human platelet mem- Iredale, P.A., Martin, K.F., Hill, S.J. and Kendall, D.A. branes (226) 281 Agonist-induced changes in [Ca**}, in N1E-115 cells: differential Nicholls, D.G., see Pocock, J.M. (226) 343 effects of bradykinin and carbachol (226) 163 Nomoto, T., see Muraki, T. (226) 311 Irie, K., see Muraki, T. (226) 311 Isaac, L., see Pandey, G.N. (226) 303 Obermaier-Skrobranek, B., see Ungerer, M. (226) 381 O’Donovan, M.C., Buckland, P.R., Spurlock, G. and McGuffin, P. Jackisch, R., Huang, H.Y., Rensing, H., Lauth, D., Allgaier, C. and Bi-directional changes in the levels of messenger RNAs encoding Hertting, G. y-aminobutyric acid, receptor a subunits after flurazepam treat- a,-Adrenoceptor mediated inhibition of exocytotic noradrenaline ment (226) 335 release in the absence of extracellular Ca** (226) 245 Okajima, F., see Tomura, H. (226) 363 Jauzac, P., see Polastron, J. (226) 133 Okamoto, K., see Sakuta, H. (226) 199 Just, I., see Koch, G. (226) 87 Olivera, B.M., see Hammerland, L.G. (226) 239 Ottallah, M., see Honscha, W. (226) 215 Kendall, D.A., see Iredale, P.A. (226) 163 Kiseleva, V.I., see Vrana, O. (226) 5 Palacios, J.M., see Pombo-Villar, E. (226) 317 Koch, G., Habermann, B., Mohr, C., Just, I. and Aktories, K. Pandey, G.N., Pandey, S.C., Isaac, L. and Davis, J.M. ADP-ribosylation of rho proteins is inhibited by melittin, mast Effect of electroconvulsive shock on 5-HT, and a,-adrenoceptors cell degranulating peptide and compound 48/80 (226) 87 and phosphoinositide signalling system in rat brain (226) 303 Kondo, Y., see Tomura, H. (226) 363 Pandey, S.C., see Pandey, G.N. (226) 303 Kowatch, M.A., see Villalobos-Molina, R. (226) 129 Pasternak, G.W., see Cheng, J. (226) 15 Kozikowski, A.P., see Reynolds, I.J. (226) 53 Perzborn, E., see Theis, J.G.W. (226) 149 Kubota, Y., see Tsujino, T. (226) 69 Pettinger, W.A., see Sun, L. (226) 367 Petzinger, E., see Honscha, W. (226) 215 Lang, D. and Lewis, M.J. Pierce, S.K., see Reilly, T.M. (226) 179 The effects of flosequinan on endothelin-1-induced changes in Pocock, J.M. and Nicholls, D.G. inositol 1,4,5-trisphosphate levels and protein kinase C activity in A toxin (Aga-GI) from the venom of the spider Agelenopsis rat aorta (226) 259 aperta inhibits the mammalian presynaptic Ca?* channel coupled Langer, S.Z., see Graham, D. (226) 373 to glutamate exocytosis (226) 343 Lauth, D., see Jackisch, R. (226) 245 Polastron, J., Jauzac, P. and Meunier, J.-C. Lazdunski, M., see Szewczyk, A. (226) 175 The 6-opioid receptor in neuroblastoma X glioma NG 108-15 Lewis, M.J., see Lang, D. (226) 259 hybrid cells is strongly precoupled to a G-protein (226) 133 Liu, C., see Safrany, S.T. (226) 265 Pombo-Villar, E., Wiederhold, K.-H., Mengod, G., Palacios, J.M., Loew, G.H., see Maguire, P.A. (226) 233 Supavilai, P. and Boddeke, H.W.G.M. Lohse, M.J., see Ungerer, M. (226) 381 Stereoisomerism and muscarinic receptor agonists: synthesis and effects of the stereoisomers of 3-[5-(3-amino-1,2,4-oxadiazol)yl]- Maelicke, A., see Soskié, V. (226) 109 1-azabicyclo[2.2.1]heptane (226) 317 Maguire, P.A., Villar, H.O., Davies, M.F. and Loew, G.H. Potter, B.V.L., see Safrany, S.T. (226) 265 Thermodynamic analysis of binding to the cerebellar type I Poverenny, A.M., see Vrana, O. (226) 5 benzodiazepine receptor (226) 233 Pranzatelli, M.R., see Trifiletti, R.R. (226) 377 Marmol, F., Carbonell, L., Cuffi, M.L. and Forn, J. Primus, R.J. and Gallager, D.W. Demonstration of inhibition of cyclic AMP accumulation in brain GABA, receptor subunit mRNA levels are differentially influ- by very low concentrations of lithium in the presence of a-adren- enced by chronic FG 7142 and diazepam exposure (226) 21 oceptor blockade (226) 93 Martin, K.F., see Iredale, P.A. (226) 163 Raghunathan, G., see Cruciani, R.A. (226) 287 Martinez, J., see Galas, M.C. (226) 35 Rajdev, S., see Reynolds, I.J. (226) 53 McGuffin, P., see O’Donovan, M.C. (226) 335 Reber, B.F.X., see Neuhaus, R. (226) 183 Mengod, G., see Pombo-Villar, E. (226) 317 Reilly, T.M., Christ, D.D., Duncia, J.V., Pierce, S.K. and Timmer- Meunier, J.-C., see Polastron, J. (226) 133 mans, P.B.M.W.M. Minneman, K.P., see Han, C. (226) 141 Monoclonal antibodies to the nonpeptide angiotensin II receptor Miyajima, T., see Tsujino, T. (226) 69 antagonist, losartan (226) 179 Miyamoto, A., see Villalobos-Molina, R. (226) 129 Rensing, H., see Jackisch, R. (226) 245 Mohr, C., see Koch, G. (226) 87 Reynolds, I.J., Rothermund, K., Rajdev, S., Faugq, A.H. and Muller, W.E.G., Schroder, H.C., Ushijima, H., Dapper, J. and Bor- Kozikowski, A.P. mann, J. [!*°1]Thienylphencyclidine, a novel ligand for the NMDA recep- gp120 of HIV-1 induces apoptosis in rat cortical cell cultures: tor (226) 53 prevention by memantine (226) 209 Richards, S.J., see Challiss, R.A.J. (226) 121 Muraki, T., Irie, K., Uchida, Y. and Nomoto, T. Richelson, E., see Yamada, M. (226) 187 Developmental changes in the effect of atrial natriuretic peptide Riederer, P., see Gerlach, M. (226) 97 on tissue cyclic GMP content and particulate guanylate cyclase Roques, B.P., see Cheng, J. (226) 15 activity of aorta, kidney and lung of rats (226) 311 Ross, S.B., see Ericson, H. (226) 157 385 Roth, G.S., see Villalobos-Molina, R. (226). 129 Tomura, H., Okajima, F. and Kondo, Y. Rothermund, K., see Reynolds, I.J. (226) 53 Discrimination between two types of P, purinoceptors by suramin in rat hepatocytes (226) 363 Saavedra, J.M., see Tsutsumi, K. (226) 169 Trifiletti, R.R. and Pranzatelli, M.R. Sabra, R. and Branch, R.A. ACTH binds to [*H]MK-801-labelled rat hippocampal NMDA Effect of amphotericin B on intracellular calcium levels in cul- receptors (226) 377 tured glomerular mesangial cells (226) 79 Tsujino, T., Sano, H., Kubota, Y., Hsieh, S.-T., Miyajima, T., Saito, Safrany, S.T., Wilcox, R.A., Liu, C., Potter, B.V.L. and Nahorski, K., Nakajima, M., Saito, N. and Yokoyama, M. S.R. Expression of Fos-like immunoreactivity by yohimbine and cloni- 3-Position modification of myo-inositol 1,4,5-trisphosphate: con- dine in the rat brain (226) 69 sequences for intracellular Ca** mobilisation and enzyme recog- Tsutsumi, K., Zorad, S. and Saavedra, J.M. nition (226) 265 The AT, subtype of the angiotensin II receptors has differential Saito, K., see Tsujino, T. (226) 69 sensitivity to dithiothreitol in specific brain nuclei of young rats Saito, N., see Tsujino, T. (226) 69 (226) 169 Sakai, Y., see Sakuta, H. (226) 199 Sakuta, H., Sekiguchi, M., Okamoto, K. and Sakai, Y. Uchida, Y., see Muraki, T. (226) 311 Inactivation of glibenclamide-sensitive K* channels in Xenopus Umemura, S., see Sun, L. (226) 367 oocytes by various calmodulin antagonists (226) 199 Undie, A.S. and Friedman, E. Sano, H., see Tsujino, T. (226) 69 Selective dopaminergic mechanism of dopamine and SKF38393 Scapagnini, U., see Sortino, M.A. (226) 273 stimulation of inositol phosphate formation in rat brain (226) 297 Schenk, A., see Honscha, W. (226) 215 Ungerer, M., Obermaier-Skrobranek, B. and Lohse, M.J. Schrader, J., see Hartmann, M. (226) 225 Adenosine A, receptor gene structure and regulation in nor- Schroder, H.C., see Miiller, W.E.G. (226) 209 motensive and spontaneously hypertensive rats (226) 381 Schuh, K., see Honscha, W. (226) 215 Ushijima, H., see Miller, W.E.G. (226) 209 Schwindt, P., see Greene, C. (226) 279 Sekiguchi, M., see Sakuta, H. (226) 199 Valliere, J.E., DeLuca, A.W. and Shreeve, S.M. Shreeve, S.M. and Valliere, J.E. Reconstitution of a,-adrenoceptors having high affinity for pra- The a,-adrenoceptor is inactivated by alterations in membrane zosin (226) 191 phospholipids (226) 29 Valliere, J.E., see Shreeve, S.M. (226) 29 Shreeve, S.M., see Valliere, J.E. (226) 191 Van der Bent, A., Ter Laak, A.M., IJzerman, A.P. and Soudijn, W. Sortino, M.A., Aleppo, G., Scapagnini, U. and Canonico, P.L. Molecular modelling of asperlicin derived cholecystokinin A re- Ipriflavone inhibits phosphoinositide hydrolysis and Ca** uptake ceptor antagonists (226) 327 in the osteoblast-like UMR-106 cells (226) 273 Villalobos-Molina, R., Miyamoto, A., Kowatch, M.A. and Roth, G.S. Soskié, V. and Maelicke, A. a,-Adrenoceptors in parotid cells: age does not alter the ratio of Synthesis and characterization of biotinylated and photoactivat- a1, and a;p subtypes (226) 129 able neuroleptics. Novel bifunctional probes for dopamine recep- Villar, H.O., see Maguire, P.A. (226) 233 tors (226) 109 Vrana, O., Kiseleva, V.I., Poverenny, A.M. and Brabec, V. Soudijn, W., see Van der Bent, A. (226) 327 Conversion of DNA adducts of antitumour cis-diammine- Spurlock, G., see O’Donovan, M.C. (226) 335 dichloroplatinum(II). Immunochemical analysis (226) 5 Stanley, E.F., see Cruciani, R.A. (226) 287 Vray, B., see Coquette, A. (226) 1 Sun, L., Umemura, S., Chun, M. and Pettinger, W.A. Northern blot and ribonuclease protection study of a -adrenoc- Wiederhold, K.-H., see Pombo-Villar, E. (226) 317 eptor subtypes in cultured cell lines (226) 367 Wilcox, R.A., see Safrany, $.T. (226) 265 Supavilai, P., see Pombo-Villar, E. (226) 317 Szewczyk, A., De Weille, J.R. and Lazdunski, M. Yamada, M., Yamada, M. and Richelson, E. TMB-8 (8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate) in- Block of neurotensin receptor down-regulation by an aminos- hibits the ATP-sensitive K* channel (226) 175 teroid in N1E-115 cells (226) 187 Yamada, M., see Yamada, M. (226) 187 Tachado, S.D., see Abdel-Latif, A.A. (226) 351 Yokoyama, M., see Tsujino, T. (226) 69 Ter Laak, A.M., see Van der Bent, A. (226) 327 Yoshikami, D., see Hammerland, L.G. (226) 239 Theis, J.G.W., Dellweg, H., Perzborn, E. and GroB, R. Youdim, M.B.H., see Gerlach, M. (226) 97 pH dependency of the binding of [7H]BAY U 3405 and various Yousufzai, S.Y.K., see Abdel-Latif, A.A. (226) 351 non-labelled ligands to the thromboxane A,/prostaglandin H, receptor of human platelet membranes (226) 149 Zasloff, M., see Cruciani, R.A. (226) 287 Timmermans, P.B.M.W.M., see Reilly, T.M. (226) 179 Zorad, S., see Tsutsumi, K. (226) 169 European Journal of Pharmacology — Molecular Pharmacology Section, 226 (1992) 387-395 © 1992 Elsevier Science Publishers B.V. All rights reserved 0922-4106 /92/$05.00 Key word index ACTH Norepinephrine; Ca**; Smooth muscle (Han, C. (226) 141) Myoclonus; Epilepsy; NMDA receptors (Trifiletti, R.R. (226) 377) Electroconvulsive shock; Brain (rat); S-HT, receptors; Phosphoinosi- Adenosine tide hydrolysis (Pandey, G.N. (226) 303) Adenosine receptors; Insulin sensitivity; Glucose transport; Amino acid transport; Skeletal muscle (Challiss, R.A.J. (226) 121) a,-Adrenoceptors Fos; Yohimbine; Clonidine; Guanabenz (Tsujino, T. (226) 69) Adenosine receptors Adenosine; Insulin sensitivity; Glucose transport; Amino acid trans- 8 ,-Adrenoceptors port; Skeletal muscle (Challiss, R.A.J. (226) 121) Amitriptyline; Xerostomia; Cytosolic free Ca**: a ,-Adrenoceptors; Muscarinic acetylcholine receptors; Parotid gland; Salivary glands Adenosine A, receptors (Glenert, U. (226) 43) Polymerase chain reaction; Spontaneously hypertensive rat (SHR) (Ungerer, M. (226) 381) a ,-Adrenoceptor subtypes Parotid cells; Aging (Villalobos-Molina, R. (226) 129) Adenylate cyclase 5-Opioid receptors; NG 108-15 hybrid cell; [*H]Etorphine; [>H]Di- Afterdepolarization prenorphine; 5’-Guanylylimidophosphate (GppNHp); Sucrose gradi- Metabotropic receptors; Glutamate (Greene, C. (226) 279) ents; G-proteins (Polastron, J. (226) 133) Aging Platelets (human); 5-HT (5-hydroxytryptamine, serotonin) (Newman, a,-Adrenoceptor subtypes; Parotid cells (Villalobos-Molina, R. (226) M.E. (226) 281) 129) ADP-ribosyltransferase C3 (Clostridium botulinum) Amino acid transport Guanine nucleotide-binding proteins (small); rho proteins; Melittin; Adenosine; Adenosine receptors; Insulin sensitivity; Glucose trans- Mast cell degranulating peptide; Compound 48/80 (Koch, G. (226) port; Skeletal muscle (Challiss, R.A.J. (226) 121) 87) Amitriptyline a ,-Adrenoceptor Xerostomia; Cytosolic free Ca**; a,-Adrenoceptors; 8 ,-Adrenocep- Membrane lipids; Phospholipases; Phospholipase C; Phospholipids; tors; Muscarinic acetylcholine receptors; Parotid gland; Salivary Aorta (Shreeve, S.M. (226) 29) glands (Glenert, U. (226) 43) B-Adrenoceptor cAMP Calmodulin antagonist; Cromakalim; ATP-sensitive K* channel; Lithium chloride; Norepinephrine; Isoprenaline; Phenoxybenzamine; Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; Propranolol (Marmol, F. (226) 93) Chlorpromazine; Haloperidol; Sulfonylurea; Glibenclamide; cAMP; Isoproterenol (Sakuta, H. (226) 199) Calmodulin antagonist; Cromakalim; ATP-sensitive K~* channel; Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; a,-Adrenoceptor mechanism Chlorpromazine; Haloperidol; Sulfonylurea; Glibenclamide; B- 3,4-Diaminopyridine; Noradrenaline release; Hippocampus; Ca** Adrenoceptor; Isoproterenol (Sakuta, H. (226) 199) (intracellular); (Rat); (Rabbit) (Jackisch, R. (226) 245) Dopamine receptors; Vascular smooth muscle (rat); Mesenteric a,-Adrenoceptor mRNA artery; Thiol group (Hall, A.S. (226) 253) HT29 cells; OK cells; NG108 cells (Sun, L. (226) 367) Iris sphincter (dog); Smooth muscle; Muscarinic stimulation; Inositol a-Adrenoceptors trisphosphate; Ca**; Cross-talk; Contraction-relaxation (Abdel-Latif, Prazosin; Receptor reconstitution; Detergent solubilization; Recep- A.A. (226) 351) tor conformation (Valliere, J.E. (226) 191) cAMP accumulation Dopamine receptors; Inositol phosphates; Phosphoinositides; Stria- Cholecystokinin, CCK, receptors; Synaptoneurosomes (guinea pig, tum (rat); 5-HT receptors (Undie, A.S. (226) 297) cerebral cortex); Boc-[Leu*!]CCK-4 binding; Inositol phosphate ac- cumulation; *°Ca** efflux (Galas, M.C. (226) 35) a ,-Adrenoceptors Amitriptyline; Xerostomia; Cytosolic free Ca’*; B,-Adrenoceptors; Amphotericin B Muscarinic acetylcholine receptors; Parotid gland; Salivary glands Mesangial cells; Ca** (intracellular); Diltiazem; Theophylline (Sabra, (Glenert, U. (226) 43) R. (226) 79) 388 Angiotensin AT, receptor antagonists Benzodiazepine (receptor binding) Angiotensin II; Monoclonal antibodies; Losartan (Reilly, T.M. (226) Thermodynamics; Benzodiazepine receptor (type I); Cerebellum 179) (Maguire, P.A. (226) 233) Angiotensin II Benzodiazepine receptors (peripheral) Angiotensin AT, receptor antagonists; Monoclonal antibodies; Kidney (rat); Angiotensin II (Holmes, P.V. (226) 189) Losartan (Reilly, T.M. (226) 179) Benzodiazepine receptor (type I) Kidney (rat); Benzodiazepine receptors (peripheral) (Holmes, P.V. Benzodiazepine (receptor binding); Thermodynamics; Cerebellum (226) 189) (Maguire, P.A. (226) 233) Angiotensin II receptor subtypes Benzodiazepines AT, receptors; Sulfhydryl reducing agents; Dithiothreitol; Losartan Tolerance; GABA , receptor; mRNA levels; (Rat) (O’Donovan, M.C. (DuP 753); Brain development (Tsutsumi, K. (226) 169) (226) 335) Antibacterial peptide Boc-[Leu*!]CCK-4 binding Artificial bilayer; Ion channel reconstitution; Peptide ion channel Cholecystokinin; CCK, receptors; Synaptoneurosomes (guinea pig, (Cruciani, R.A. (226) 287) cerebral cortex); Inositol phosphate accumulation; cAMP accumula- tion; *Ca?* efflux (Galas, M.C. (226) 35) Aorta a,-Adrenoceptor; Membrane lipids; Phospholipases; Phospholipase Brain development C; Phospholipids (Shreeve, S.M. (226) 29) Angiotensin II receptor subtypes; AT, receptors; Sulfhydryl reducing agents; Dithiothreitol; Losartan (DuP 753) (Tsutsumi, K. (226) 169) Atrial natriuretic peptide (ANP); Guanylate cyclase; Ontogenesis; Kidney; Lung (Muraki, T. (226) 311) Brain (rat) Electroconvulsive shock; a,-Adrenoceptors; 5-HT, receptors; Phos- Apoptosis phoinositide hydrolysis (Pandey, G.N. (226) 303) Human immunodeficiency virus type 1 (HIV-1); Cortical cells; Me- mantine; NMDA receptor; gp120 (Miller, W.E.G. (226) 209) Bumetanide transport Artificial bilayer Loop diuretics; Photoaffinity labeling; Sinusoidal plasma membrane Antibacterial peptide; Ion channel reconstitution; Peptide ion chan- (rat liver); Integral plasma membrane proteins; Two-dimensional gel nel (Cruciani, R.A. (226) 287) electrophoresis (Honscha, W. (226) 215) Ca*+ ATP Suramin; P, purinoceptor; Hepatocytes; (Rat) (Tomura, H. (226) a,-Adrenoceptors; Norepinephrine; Smooth muscle (Han, C. (226) 363) 141) ATP-sensitive K * channel Iris sphincter (dog); Smooth muscle; Muscarinic stimulation; cAMP; Calmodulin antagonist; Cromakalim; Oocyte (Xenopus laevis); W-7; Inositol trisphosphate; Cross-talk; Contraction-relaxation (Abdel- W-5; Phenothiazines; Trifluoperazine; Chlorpromazine; Haloperidol; Latif, A.A. (226) 351) Sulfonylurea; Glibenclamide; cAMP; B-Adrenoceptor; Isoproterenol (Sakuta, H. (226) 199) Ca?+ channel Calmodulin; CGS 9343B; Patch clamp; Fura-2 (Neuhaus, R. (226) ATP-sensitive potassium channel 183) TMB-8 (8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate); B- Cells (Szewezyk, A. (226) 175) Ca?* channel (mammalian, presynaptic) Spider toxin; Glutamate (Pocock, J.M. (226) 343) AT, receptors Angiotensin II receptor subtypes; Sulfhydryl reducing agents; Dithio- 4SCa?* efflux threitol; Losartan (DuP 753); Brain development (Tsutsumi, K. (226) Cholecystokinin; CCK, receptors; Synaptoneurosomes (guinea pig, 169) cerebral cortex); Boc-[Leu*!]CCK-4 binding; Inositol phosphate ac- cumulation; cAMP accumulation (Galas, M.C. (226) 35) Atrial natriuretic peptide (ANP) Guanylate cyclase; Ontogenesis; Aorta; Kidney; Lung (Muraki, T. Ca?*+ (intracellular) (226) 311) Amphotericin B; Mesangial cells; Diltiazem; Theophylline (Sabra, R. (226) 79) BAY U 3405 Thromboxane A; Thromboxane A, receptor antagonist; Thrombox- ane A, receptor agonist; pH dependency; Radioligand binding; 3,4-Diaminopyridine; Noradrenaline release; Hippocampus; a,- Platelet membranes (human) (Theis, J.G.W. (226) 149) Adrenoceptor mechanism; (Rat); (Rabbit) (Jackisch, R. (226) 245) Benzodiazepine Calmodulin Tolerance; GABA, receptor complex (a, subunit; y, subunit; B, Ca**+ channel; CGS 9343B; Patch clamp; Fura-2 (Neuhaus, R. (226) subunit); (Rat) (Primus, R.J. (226) 21) 183) Calmodulin antagonist Clonidine Cromakalim; ATP-sensitive K* channel; Oocyte (Xenopus laevis); Fos; a,-Adrenoceptors; Yohimbine; Guanabenz (Tsujino, T. (226) W-7; W-5; Phenothiazines; Trifluoperazine; Chlorpromazine; 69) Haloperidol; Sulfonylurea; Glibenclamide; cAMP; B-Adrenoceptor; Isoproterenol (Sakuta, H. (226) 199) Compound 48 / 80 Guanine nucleotide-binding proteins (small); rho proteins; ADP- Ca** mobilization ribosyltransferase C3 (Clostridium botulinum); Melittin; Mast cell Second messenger; Inositdl phosphate analogues (Safrany, S.T. (226) degranulating peptide (Koch, G. (226) 87) 265) Conantokin NMDA receptor; Oocytes (Xenopus) (Hammerland, L.G. (226) 239) 4SCa?* uptake Ipriflavone; Phosphoinositides; UMR-106 cells (Sortino, M.A. (226) Contraction-relaxation 273) Iris sphincter (dog); Smooth muscle; Muscarinic stimulation; cAMP; Inositol trisphosphate; Ca?*; Cross-talk (Abdel-Latif, A.A. (226) CCK, receptor antagonists 351) Cholecystokinin receptor; Molecular modelling; Devazepide; L- 364,718 (Van der Bent, A. (226) 327) Cortical cells Human immunodeficiency virus type 1 (HIV-1); Apoptosis; Meman- CCK, receptors tine; NMDA receptor; gp120 (Miiller, W.E.G. (226) 209) Cholecystokinin; Synaptoneurosomes (guinea pig, cerebral cortex); Boc-[Leu*! ]CCK-4 binding; Inositol phosphate accumulation; cAMP Cromakalim accumulation; *°Ca?* efflux (Galas, M.C. (226) 35) Calmodulin antagonist; ATP-sensitive K* channel; Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; Chlorpromazine; Cell culture Haloperidol; Sulfonylurea; Glibenclamide; cAMP; B-Adrenoceptor; Ifenprodil; Neurotoxicity; NMDA receptors (Graham, D. (226) 373) Isoproterenol (Sakuta, H. (226) 199) Cross-talk B-Cells Iris sphincter (dog); Smooth muscle; Muscarinic stimulation; cAMP; TMB-8 (8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate); ATP- sensitive potassium channel (Szewcezyk, A. (226) 175) Inositol trisphosphate; Ca?*: Contraction-relaxation (Abdel-Latif, A.A. (226) 351) Cerebellum CRI receptors Benzodiazepine (receptor binding); Thermodynamics; Benzodi- Peritoneal cells (rat); Phagocytosis (bacterial); Eicosanoids; In- azepine receptor (type I) (Maguire, P.A. (226) 233) domethacin; Fc receptors (Coquette, A. (226) 1) Cerebral cortex (rat) Cultured cells Ouabain binding site (high affinity); Melatonin; [*H]Ouabain Cisplatin; Pt-DNA adducts; Enzyme-linked immunosorbent assay (Acuna Castroviejo, D. (226) 59) (ELISA); Epitope (Vrana, O. (226) 5) c-fos expression Cytosolic free Ca2* Muscarinic receptor subtypes; Muscarinic receptor agonists; Stereo- Amitriptyline; Xerostomia; a@,-Adrenoceptors; £6,-Adrenoceptors; chemistry (absolute); Superior cervical ganglion (rat); Hippocampal Muscarinic acetylcholine receptors; Parotid gland; Salivary glands slice (rat); Ileum (guinea pig); Hybridization (in situ) (Pombo- Villar, (Glenert, U. (226) 43) E. (226) 317) L-Deprenyl CGS 9343B Monoamine oxidase inhibitors; Parkinson’s disease; Neuroprotective Ca** channel; Calmodulin; Patch clamp; Fura-2 (Neuhaus, R. (226) mechanisms (Gerlach, M. (226) 97) 183) Detergent solubilization a-Adrenoceptors; Prazosin; Receptor reconstitution; Receptor con- Chlorpromazine formation (Valliere, J.E. (226) 191) Calmodulin antagonist; Cromakalim; ATP-sensitive K* channel; Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; Devazepide Haloperidol; Sulfonylurea; Glibenclamide; cAMP; B-Adrenoceptor; Cholecystokinin receptor; CCK, receptor antagonists; Molecular Isoproterenol (Sakuta, H. (226) 199) modelling; L-364,718 (Van der Bent, A. (226) 327) Cholecystokinin 3,4-Diaminopyridine CCK , receptors; Synaptoneurosomes (guinea pig, cerebral cortex); Noradrenaline release; Hippocampus; Ca** (intracellular); a@>- Boc-[Leu*! ]CCK-4 binding; Inositol phosphate accumulation; cAMP Adrenoceptor mechanism; (Rat); (Rabbit) (Jackisch, R. (226) 245) accumulation; *°Ca?* efflux (Galas, M.C. (226) 35) Diltiazem Cholecystokinin receptor Amphotericin B; Mesangial cells; Ca?* (intracellular); Theophylline CCK, receptor antagonists; Molecular modelling; Devazepide; L- (Sabra, R. (226) 79) 364,718 (Van der Bent, A. (226) 327) [3H] Diprenorphine Cisplatin 5-Opioid receptors; NG 108-15 hybrid cell; [*HJEtorphine; 5’- Pt-DNA adducts; Enzyme-linked immunosorbent assay (ELISA); Guanylylimidophosphate (GppNHp); Sucrose gradients; Adenylate Epitope; Cultured cells (Vrana, O. (226) 5) cyclase; G-proteins (Polastron, J. (226) 133) 390 Dithiothreitol GABA, receptor complex (a, subunit; y, subunit; 8, subunit) Angiotensin II receptor subtypes; AT, receptors; Sulfhydryl reducing Benzodiazepine; Tolerance; (Rat) (Primus, R.J. (226) 21) agents; Losartan (DuP 753); Brain development (Tsutsumi, K. (226) 169) Glibenclamide Calmodulin antagonist; Cromakalim; ATP-sensitive K* channel; Dopamine receptors Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; cAMP; Vascular smooth muscle (rat); Mesenteric artery; Thiol group Chlorpromazine; Haloperidol; Sulfonylurea; cAMP; 6-Adrenocep- (Hall, A.S. (226) 253) tor; Isoproterenol (Sakuta, H. (226) 199) Inositol phosphates; Phosphoinositides; Striatum (rat); a-Adreno- Glucose transport ceptors; 5-HT receptors (Undie, A.S. (226) 297) Adenosine; Adenosine receptors; Insulin sensitivity; Amino acid transport; Skeletal muscle (Challiss, R.A.J. (226) 121) Dopamine D, receptors Q Dopamine D, receptors (Soski¢, V. (226) 109) Glutamate Metabotropic receptors; Afterdepolarization (Greene, C. (226) 279) Dopamine D, receptors — Dopamine D, receptors (Soski¢, V. (226) 109) Spider toxin; Ca** channel (mammalian, presynaptic) (Pocock, J.M. (226) 343) Down-regulation gp120 Neurotensin receptors; U-73122 (Yamada, M. (226) 187) Human immunodeficiency virus type 1 (HIV-1); Apoptosis; Cortical cells; Memantine; NMDA receptor (Miiller, W.E.G. (226) 209) Eicosanoids Peritoneal cells (rat); Phagocytosis (bacterial); Indomethacin; CR1 G-proteins receptors; Fc receptors (Coquette, A. (226) 1) 5-Opioid receptors; NG 108-15 hybrid cell; [*H]Etorphine; [*H]Di- prenorphine; 5’-Guanylylimidophosphate (GppNHp); Sucrose gradi- Electroconvulsive shock ents; Adenylate cyclase (Polastron, J. (226) 133) Brain (rat); a@,-Adrenoceptors; 5-HT, receptors; Phosphoinositide hydrolysis (Pandey, G.N. (226) 303) Guanabenz Fos; a,-Adrenoceptors; Yohimbine; Clonidine (Tsujino, T. (226) 69) Endothelin-1 Inositol 1,4,5-trisphosphate; Protein kinase C; Flosequinan (Lang, D. Guanine nucleotide-binding proteins (small) (226) 259) rho proteins; ADP-ribosyltransferase C3 (Clostridium botulinum); Melittin; Mast cell degranulating peptide; Compound 48/80 (Koch, Enzyme-linked immunosorbent assay (ELISA) G. (226) 87) Cisplatin; Pt-DNA adducts; Epitope; Cultured cells (Vrana, O. (226) 5) Guanylate cyclase Atrial natriuretic peptide (ANP); Ontogenesis; Aorta; Kidney; Lung Epilepsy (Muraki, T. (226) 311) ACTH; Myoclonus; NMDA receptors (Trifiletti, R.R. (226) 377) 5’-Guanylylimidophosphate (GppNHp) Epitope 5-Opioid receptors; NG 108-15 hybrid cell; [*H]Etorphine; [*>H]Di- Cisplatin; Pt-DNA adducts; Enzyme-linked immunosorbent assay prenorphine; Sucrose gradients; Adenylate cyclase; G-proteins (ELISA); Cultured cells (Vrana, O. (226) 5) (Polastron, J. (226) 133) [3H] Etorphine Haloperidol 5-Opioid receptors; NG 108-15 hybrid cell; [*H]Diprenorphine; 5’- Remoxipride; o Recognition sites (Ericson, H. (226) 157) Guanylylimidophosphate (GppNHp); Sucrose gradients; Adenylate cyclase; G-proteins (Polastron, J. (226) 133) Calmodulin antagonist; Cromakalim; ATP-sensitive K* channel; Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; Fc receptors Chlorpromazine; Sulfonylurea; Glibenclamide; cAMP; $-Adrenoc- Peritoneal cells (rat); Phagocytosis (bacterial); Eicosanoids; In- eptor; Isoproterenol (Sakuta, H. (226) 199) domethacin; CR1 receptors (Coquette, A. (226) 1) Heart Flosequinan Protein kinase C; Protein (15 kDa); Phospholamban (Hartmann, M. Endothelin-1; Inositol 1,4,5-trisphosphate; Protein kinase C (Lang, (226) 225) D. (226) 259) Hepatocytes Fos Suramin; ATP; P, purinoceptor; (Rat) (Tomura, H. (226) 363) a,-Adrenoceptors; Yohimbine; Clonidine; Guanabenz (Tsujino, T. (226) 69) Hippocampal slice (rat) Muscarinic receptor subtypes; Muscarinic receptor agonists; Stereo- Fura-2 chemistry (absolute); Superior cervical ganglion (rat); Ileum (guinea Ca?* channel; Calmodulin; CGS 9343B; Patch clamp (Neuhaus, R. pig); c-fos expression; Hybridization (in situ) (Pombo-Villar, E. (226) (226) 183) 317) GABA , receptor Hippocampus Benzodiazepines; Tolerance; mRNA levels; (Rat) (O’Donovan, M.C. 3,4-Diaminopyridine; Noradrenaline release; Ca”* (intracellular); (226) 335) a,-Adrenoceptor mechanism; (Rat); (Rabbit) (Jackisch, R. (226) 245) HT29 cells Ion channel reconstitution a,-Adrenoceptor mRNA; OK cells; NG108 cells (Sun, L. (226) 367) Antibacterial peptide; Artificial bilayer; Peptide ion channel (Cruciani, R.A. (226) 287) 5-HT (5-hydroxytryptamine, serotonin) Adenylate cyclase; Platelets (human) (Newman, M.E. (226) 281) Ipriflavone Phosphoinositides; UMR-106 cells; “*Ca** uptake (Sortino, M.A. 5-HT receptors (226) 273) Dopamine receptors; Inositol phosphates; Phosphoinositides; Stria- Iris sphincter (dog) tum (rat); a-Adrenoceptors (Undie, A.S. (226) 297) Smooth muscle; Muscarinic stimulation; cAMP; Inositol trisphos- phate; Ca**; Cross-talk; Contraction-relaxation (Abdel-Latif, A.A. 5-HT, receptors (226) 351) Electroconvulsive shock; Brain (rat); a,-Adrenoceptors; Phospho- inositide hydrolysis (Pandey, G.N. (226) 303) Isoprenaline Lithium chloride; cAMP; Norepinephrine; Phenoxybenzamine; Pro- Human immunodeficiency virus type 1 (HIV-1) pranolol (Marmol, F. (226) 93) Apoptosis; Cortical cells; Memantine; NMDA receptor; gp120 (Miller, W.E.G. (226) 209) Isoproterenol Calmodulin antagonist; Cromakalim; ATP-sensitive K* channel; Hybridization (in situ) Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; Muscarinic receptor subtypes; Muscarinic receptor agonists; Stereo- Chlorpromazine; Haloperidol; Sulfonylurea; Glibenclamide; cAMP; chemistry (absolute); Superior cervical ganglion (rat); Hippocampal B-Adrenoceptor (Sakuta, H. (226) 199) slice (rat); Ileum (guinea pig); c-fos expression (Pombo-Villar, E. (226) 317) Kidney Atrial natriuretic peptide (ANP); Guanylate cyclase; Ontogenesis; Ifenprodil Aorta; Lung (Muraki, T. (226) 311) Neurotoxicity; Cell culture; NMDA receptors (Graham, D. (226) 373) Kidney (rat) Benzodiazepine receptors (peripheral); Angiotensin II (Holmes, P.V. Ileum (guinea pig) (226) 189) Muscarinic receptor subtypes; Muscarinic receptor agonists; Stereo- L-364,718 chemistry (absolute); Superior cervical ganglion (rat); Hippocampal Cholecystokinin receptor; CCK, receptor antagonists; Molecular slice (rat); c-fos expression; Hybridization (in situ) (Pombo-Villar, E. modelling; Devazepide (Van der Bent, A. (226) 327) (226) 317) © Lithium chloride Indomethacin cAMP; Norepinephrine; Isoprenaline; Phenoxybenzamine; Propra- Peritoneal cells (rat); Phagocytosis (bacterial); Eicosanoids; CR1 nolol (Marmol, F. (226) 93) receptors; Fc receptors (Coquette, A. (226) 1) Loop diuretics Inositol phosphate accumulation Bumetanide transport; Photoaffinity labeling; Sinusoidal plasma Cholecystokinin, CCK, receptors; Synaptoneurosomes (guinea pig, membrane (rat liver); Integral plasma membrane proteins; Two-di- cerebral cortex); Boc-[Leu*!]CCK-4 binding; cAMP accumulation; mensional gel electrophoresis (Honscha, W. (226) 215) SCa?* efflux (Galas, M.C. (226) 35) Losartan Inositol phosphate analogues Angiotensin II; Angiotensin AT, receptor antagonists; Monoclonal Second messenger; Ca** mobilization (Safrany, S.T. (226) 265) antibodies (Reilly, T.M. (226) 179) Losartan (DuP 753) Inositol phosphates Angiotensin II receptor subtypes; AT, receptors; Sulfhydryl reducing Dopamine receptors; Phosphoinositides; Striatum (rat); a-Adreno- ceptors; 5-HT receptors (Undie, A.S. (226) 297) agents; Dithiothreitol; Brain development (Tsutsumi, K. (226) 169) Lung Inositol trisphosphate Atrial natriuretic peptide (ANP); Guanylate cyclase; Ontogenesis; Iris sphincter (dog); Smooth muscle; Muscarinic stimulation; cAMP; Aorta; Kidney (Muraki, T. (226) 311) Ca**; Cross-talk; Contraction-relaxation (Abdel-Latif, A.A. (226) 351) Mast cell degranulating peptide Guanine nucleotide-binding proteins (small); rho proteins; ADP- Inositol 1,4,5-trisphosphate ribosyltransferase C3 (Clostridium botulinum); Melittin; Compound Endothelin-1; Protein kinase C; Flosequinan (Lang, D. (226) 259) 48 /80 (Koch, G. (226) 87) Insulin sensitivity Melatonin Adenosine; Adenosine receptors; Glucose transport; Amino acid Ouabain binding site (high affinity); [*H]Ouabain; Cerebral cortex transport; Skeletal muscle (Challiss, R.A.J. (226) 121) (rat) (Acuna Castroviejo, D. (226) 59) Integral plasma membrane proteins Melittin Bumetanide transport; Loop diuretics; Photoaffinity labeling; Sinu- Guanine nucleotide-binding proteins (small); rho proteins; ADP- soidal plasma membrane (rat liver); Two-dimensional gel elec- ribosyltransferase C3 (Clostridium botulinum); Mast cell degranulat- trophoresis (Honscha, W. (226) 215) ing peptide; Compound 48/80 (Koch, G. (226) 87) 392 Memantine Neurotoxicity Human immunodeficiency virus type 1 (HIV-1); Apoptosis; Cortical Ifenprodil; Cell culture; NMDA receptors (Graham, D. (226) 373) cells; NMDA receptor; gp120 (Miiller, W.E.G. (226) 209) NG108 cells Membrane lipids a,-Adrenoceptor mRNA; HT29 cells; OK cells (Sun, L. (226) 367) a,-Adrenoceptor; Phospholipases; Phospholipase C; Phospholipids; Aorta (Shreeve, S.M. (226) 29) NG 108-15 hybrid cell 5-Opioid receptors; [7H]Etorphine; [*H]Diprenorphine; 5’-Guanyl- Mesangial cells ylimidophosphate (GppNHp); Sucrose gradients; Adenylate cyclase; Amphotericin B; Ca’** (intracellular); Diltiazem; Theophylline G-proteins (Polastron, J. (226) 133) (Sabra, R. (226) 79) NMDA receptor [!>1]Thienylphencyclidine; Polyamines (Reynolds, I.J. (226) 53) Mesenteric artery cAMP; Dopamine receptors; Vascular smooth muscle (rat); Thiol group (Hall, A.S. (226) 253) Human immunodeficiency virus type 1 (HIV-1); Apoptosis; Cortical cells; Memantine; gp120 (Miiller, W.E.G. (226) 209) Metabotropic receptors Glutamate; Afterdepolarization (Greene, C. (226) 279) Oocytes (Xenopus) ;C onantokin (Hammerland, L.G. (226) 239) Molecular modelling NMDA receptors Cholecystokinin receptor; CCK, receptor antagonists; Devazepide; Ifenprodil; Neurotoxicity; Cell culture (Graham, D. (226) 373) L-364,718 (Van der Bent, A. (226) 327) ACTH; Myoclonus; Epilepsy (Trifiletti, R.R. (226) 377) Monoamine oxidase inhibitors Parkinson’s disease; L-Deprenyl; Neuroprotective mechanisms Noradrenaline release (Gerlach, M. (226) 97) 3,4-Diaminopyridine; Hippocampus; Ca’* (intracellular); a,-Adren- oceptor mechanism; (Rat); (Rabbit) (Jackisch, R. (226) 245) Monoclonal antibodies Angiotensin II; Angiotensin AT, receptor antagonists; Losartan Norepinephrine (Reilly, T.M. (226) 179) Lithium chloride; cAMP; Isoprenaline; Phenoxybenzamine; Propra- nolol (Marmol, F. (226) 93) Morphine k-Opioid receptor; Naloxone benzoylhydrazone (Cheng, J. (226) 15) a ,-Adrenoceptors; Ca**; Smooth muscle (Han, C. (226) 141) Muscarinic acetylcholine receptors OK cells Amitriptyline; Xerostomia; Cytosolic free Ca?*; a,-Adrenoceptors; a,-Adrenoceptor mRNA; HT29 cells; NG108 cells (Sun, L. (226) B,-Adrenoceptors; Parotid gland; Salivary glands (Glenert, U. (226) 367) 43) Ontogenesis Muscarinic receptor agonists Atrial natriuretic peptide (ANP); Guanylate cyclase; Aorta; Kidney; Muscarinic receptor subtypes; Stereochemistry (absolute); Superior Lung (Muraki, T. (226) 311) cervical ganglion (rat); Hippocampal slice (rat); Ileum (guinea pig); c-fos expression; Hybridization (in situ) (Pombo-Villar, E. (226) 317) Oocytes (Xenopus) NMDA receptor; Conantokin (Hammerland, L.G. (226) 239) Muscarinic receptor subtypes Muscarinic receptor agonists; Stereochemistry (absolute); Superior Oocyte (Xenopus laevis) cervical ganglion (rat); Hippocampal slice (rat); Ileum (guinea pig); Calmodulin antagonist; Cromakalim; ATP-sensitive K* channel; c-fos expression; Hybridization (in situ) (Pombo-Villar, E. (226) 317) W-7; W-5; Phenothiazines; Trifluoperazine; Chlorpromazine; Haloperidol; Sulfonylurea; Glibenclamide; cAMP; B-Adrenoceptor; Muscarinic stimulation Isoproterenol (Sakuta, H. (226) 199) Iris sphincter (dog); Smooth muscle; cAMP; Inositol trisphosphate; Ca?*; Cross-talk; Contraction-relaxation (Abdel-Latif, A.A. (226) «-Opioid receptor 351) Naloxone benzoylhydrazone; Morphine (Cheng, J. (226) 15) Myoclonus 5-Opioid receptors ACTH; Epilepsy; NMDA receptors (Trifiletti, R.R. (226) 377) NG 108-15 hybrid cell; [*HJEtorphine; [*H]Diprenorphine; 5’- Guanylylimidophosphate (GppNHp); Sucrose gradients; Adenylate Naloxone benzoylhydrazone cyclase; G-proteins (Polastron, J. (226) 133) k-Opioid receptor; Morphine (Cheng, J. (226) 15) [7H]O uabain Neuroprotective mechanisms Ouabain binding site (high affinity); Melatonin; Cerebral cortex (rat) Monoamine oxidase inhibitors; Parkinson’s disease; L-Deprenyl (Acuna Castroviejo, D. (226) 59) (Gerlach, M. (226) 97) Ouabain binding site (high affinity) Neurotensin receptors Melatonin; [*H]Ouabain; Cerebral cortex (rat) (Acufia Castroviejo, Down-regulation; U-73122 (Yamada, M. (226) 187) D. (226) 59)

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European Journal of Pharmacology. Molecular Pharmacology Section 1992: Vol 226 Index PDF

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Preview European Journal of Pharmacology. Molecular Pharmacology Section 1992: Vol 226 Index

European Journal of Pharmacology — Molecular Pharmacology Section, 226 (1992) 383-385 © 1992 Elsevier Science Publishers B.V. All rights reserved 0922-/4921 /$0056.0 0 Author index Abdel-Latif, A.A., Yousufzai, S.Y.K., De, S. and Tachado, S.D. Duncia, J.V., see Reilly, T.M. (226) 179 Carbachol stimulates adenylate cyclase and phospholipase C and Durell, S.R., see Cruciani, R.A. (226) 287 muscle contraction-relaxation in a reciprocal manner in dog iris sphincter smooth muscle (226) 351 Ericson, H. and Ross, S.B. Acuna Castroviejo, D., Del Aguila, C.M., Fernandez, B., Gomar, Subchronic treatment of rats with remoxipride fails to modify 7 M.D. and Castillo, J.L. binding sites in the brain (226) 157 Characterization of ouabain high-affinity binding to rat cerebral Errol, C., see Hall, A.S. (226) 253 cortex. Modulation by melatonin (226) 59 Esbenshade, T.A., see Han, C. (226) 141 Aktories, K., see Koch, G. (226) 87 Aleppo, G., see Sortino, M.A. (226) 273 Fauq, A.H., see Reynolds, I.J. (226) 53 Allgaier, C., see Jackisch, R. (226) 245 Fernandez, B., see Acufia Castroviejo, D. (226) 59 Forn, J., see Marmol, F. (226) 93 Ball, S.G., see Hall, A.S. (226) 253 Friedman, E., see Undie, A.S. (226) 297 Balmforth, A.J., see Hall, A.S. (226) 253 Barker, J.L., see Cruciani, R.A. (226) 287 Gacel, G.A., see Cheng, J. (226) 15 Bernad, N., see Galas, M.C. (226) 35 Galas, M.C., Bernad, N. and Martinez, J. Boddeke, H.W.G.M., see Pombo-Villar, E. (226) 317 Pharmacological studies on CCK, receptors in guinea pig synap- Boeynaems, J.-M., see Coquette, A. (226) 1 toneurosomes (226) 35 Bormann, J., see Miller, W.E.G. (226) 209 Gallager, D.W., see Primus, R.J. (226) 21 Brabec, V., see Vrana, O. (226) 5 Gerlach, M., Riederer, P. and Youdim, M.B.H. Branch, R.A., see Sabra, R. (226) 79 The molecular pharmacology of L-deprenyl (226) 97 Bryson, S.E., see Hall, A.S. (226) 253 Glenert, U. Buckland, P.R., see O’Donovan, M.C. (226) 335 Effects of chronic anethole trithione and amitriptyline treatment Budohoski, L., see Challiss, R.A.J. (226) 121 on rat parotid gland signalling (226) 43 Gomar, M.D., see Acufia Castroviejo, D. (226) 59 Canonico, P.L., see Sortino, M.A. (226) 273 Graham, D., Darles, G. and Langer, S.Z. Carbonell, L., see Marmol, F. (226) 93 The neuroprotective properties of ifenprodil, a novel NMDA Castillo, J.L., see Acuna Castroviejo, D. (226) 59 receptor antagonist, in neuronal cell culture toxicity studies (226) Challiss, R.A.J., Richards, S.J. and Budohoski, L. 373 Characterization of the adenosine receptor modulating insulin Greene, C., Schwindt, P. and Crill, W. action in rat skeletal muscle (226) 121 Metabotropic receptor mediated afterdepolarization in neocorti- Cheng, J., Roques, B.P., Gacel, G.A., Huang, E. and Pasternak, cal neurons (226) 279 G.W. GroB, R., see Theis, J.G.W. (226) 149 _ K3 Opiate receptor binding in the mouse and rat (226) 15 Guy, H.R., see Cruciani, R.A. (226) 287 Christ, D.D., see Reilly, T.M. (226) 179 Chun, M., see Sun, L. (226) 367 Habermann, B., see Koch, G. (226) 87 Coquette, A., Boeynaems, J.-M. and Vray, B. Hall, A.S., Errol, C., Bryson, S.E., Ball, S.G. and Balmforth, A.J. Eicosanoids modulate CR1- and Fc-dependent bacterial phagocy- Thiol group identification at or near the agonist binding site of tosis (226) 1 the vascular dopamine receptor (226) 253 Crill, W., see Greene, C. (226) 279 Hammerland, L.G., Olivera, B.M. and Yoshikami, D. Cruciani, R.A., Barker, J.L., Durell, S.R., Raghunathan, G., Guy, Conantokin-G selectively inhibits N-methyl-D-aspartate-induced H.R., Zasloff, M. and Stanley, E.F. currents in Xenopus oocytes injected with mouse brain mRNA Magainin 2, a natural antibiotic from frog skin, forms ion chan- (226) 239 nels in lipid bilayer membranes (226) 287 Han, C., Esbenshade, T.A. and Minneman, K.P. Cuffi, M.L., see Marmol, F. (226) 93 Subtypes of a,-adrenoceptors in DDT, MF-2 and BC3H-1 clonal cell lines (226) 141 Dapper, J., see Miller, W.E.G. (226) 209 Hartmann, M. and Schrader, J. Darles, G., see Graham, D. (226) 373 Protein kinase C phosphorylates a 15 kDa protein but not phos- Davies, M.F., see Maguire, P.A. (226) 233 pholamban in intact rat cardiac myocytes (226) 225 Davis, J.M., see Pandey, G.N. (226) 303 Hertting, G., see Jackisch, R. (226) 245 De, S., see Abdel-Latif, A.A. (226) 351 Hill, S.J., see Iredale, P.A. (226) 163 Del Aguila, C.M., see Acuna Castroviejo, D. (226) 59 Holmes, P.V. and Drugan, R.C. Dellweg, H., see Theis, J.G.W. (226) 149 Angiotensin II rapidly modulates the renal peripheral benzodi- DeLuca, A.W., see Valliere, J.E. (226) 191 azepine receptor (226) 189 De Weille, J.R., see Szewczyk, A. (226) 175 Honscha, W., Ottallah, M., Schenk, A., Schuh, K. and Petzinger, E. Drugan, R.C., see Holmes, P.V. (226) 189 Separation and purification by two-dimensional gel electrophore- 384 sis of a 52-54 kDa bumetanide binding protein from rat liver Nahorski, S.R., see Safrany, S.T. (226) 265 plasma membranes (226) 215 Nakajima, M., see Tsujino, T. (226) 69 Hsieh, S.-T., see Tsujino, T. (226) 69 Neuhaus, R. and Reber, B.F.X. Huang, E., see Cheng, J. (226) 15 Inhibition of membrane currents and rises of intracellular Ca?* Huang, H.Y., see Jackisch, R. (226) 245 in PC12 cells by CGS 9343B, a calmodulin inhibitor (226) 183 Newman, M.E. IJzerman, A.P., see Van der Bent, A. (226) 327 Serotonin inhibits adenylate cyclase in human platelet mem- Iredale, P.A., Martin, K.F., Hill, S.J. and Kendall, D.A. branes (226) 281 Agonist-induced changes in [Ca**}, in N1E-115 cells: differential Nicholls, D.G., see Pocock, J.M. (226) 343 effects of bradykinin and carbachol (226) 163 Nomoto, T., see Muraki, T. (226) 311 Irie, K., see Muraki, T. (226) 311 Isaac, L., see Pandey, G.N. (226) 303 Obermaier-Skrobranek, B., see Ungerer, M. (226) 381 O’Donovan, M.C., Buckland, P.R., Spurlock, G. and McGuffin, P. Jackisch, R., Huang, H.Y., Rensing, H., Lauth, D., Allgaier, C. and Bi-directional changes in the levels of messenger RNAs encoding Hertting, G. y-aminobutyric acid, receptor a subunits after flurazepam treat- a,-Adrenoceptor mediated inhibition of exocytotic noradrenaline ment (226) 335 release in the absence of extracellular Ca** (226) 245 Okajima, F., see Tomura, H. (226) 363 Jauzac, P., see Polastron, J. (226) 133 Okamoto, K., see Sakuta, H. (226) 199 Just, I., see Koch, G. (226) 87 Olivera, B.M., see Hammerland, L.G. (226) 239 Ottallah, M., see Honscha, W. (226) 215 Kendall, D.A., see Iredale, P.A. (226) 163 Kiseleva, V.I., see Vrana, O. (226) 5 Palacios, J.M., see Pombo-Villar, E. (226) 317 Koch, G., Habermann, B., Mohr, C., Just, I. and Aktories, K. Pandey, G.N., Pandey, S.C., Isaac, L. and Davis, J.M. ADP-ribosylation of rho proteins is inhibited by melittin, mast Effect of electroconvulsive shock on 5-HT, and a,-adrenoceptors cell degranulating peptide and compound 48/80 (226) 87 and phosphoinositide signalling system in rat brain (226) 303 Kondo, Y., see Tomura, H. (226) 363 Pandey, S.C., see Pandey, G.N. (226) 303 Kowatch, M.A., see Villalobos-Molina, R. (226) 129 Pasternak, G.W., see Cheng, J. (226) 15 Kozikowski, A.P., see Reynolds, I.J. (226) 53 Perzborn, E., see Theis, J.G.W. (226) 149 Kubota, Y., see Tsujino, T. (226) 69 Pettinger, W.A., see Sun, L. (226) 367 Petzinger, E., see Honscha, W. (226) 215 Lang, D. and Lewis, M.J. Pierce, S.K., see Reilly, T.M. (226) 179 The effects of flosequinan on endothelin-1-induced changes in Pocock, J.M. and Nicholls, D.G. inositol 1,4,5-trisphosphate levels and protein kinase C activity in A toxin (Aga-GI) from the venom of the spider Agelenopsis rat aorta (226) 259 aperta inhibits the mammalian presynaptic Ca?* channel coupled Langer, S.Z., see Graham, D. (226) 373 to glutamate exocytosis (226) 343 Lauth, D., see Jackisch, R. (226) 245 Polastron, J., Jauzac, P. and Meunier, J.-C. Lazdunski, M., see Szewczyk, A. (226) 175 The 6-opioid receptor in neuroblastoma X glioma NG 108-15 Lewis, M.J., see Lang, D. (226) 259 hybrid cells is strongly precoupled to a G-protein (226) 133 Liu, C., see Safrany, S.T. (226) 265 Pombo-Villar, E., Wiederhold, K.-H., Mengod, G., Palacios, J.M., Loew, G.H., see Maguire, P.A. (226) 233 Supavilai, P. and Boddeke, H.W.G.M. Lohse, M.J., see Ungerer, M. (226) 381 Stereoisomerism and muscarinic receptor agonists: synthesis and effects of the stereoisomers of 3-[5-(3-amino-1,2,4-oxadiazol)yl]- Maelicke, A., see Soskié, V. (226) 109 1-azabicyclo[2.2.1]heptane (226) 317 Maguire, P.A., Villar, H.O., Davies, M.F. and Loew, G.H. Potter, B.V.L., see Safrany, S.T. (226) 265 Thermodynamic analysis of binding to the cerebellar type I Poverenny, A.M., see Vrana, O. (226) 5 benzodiazepine receptor (226) 233 Pranzatelli, M.R., see Trifiletti, R.R. (226) 377 Marmol, F., Carbonell, L., Cuffi, M.L. and Forn, J. Primus, R.J. and Gallager, D.W. Demonstration of inhibition of cyclic AMP accumulation in brain GABA, receptor subunit mRNA levels are differentially influ- by very low concentrations of lithium in the presence of a-adren- enced by chronic FG 7142 and diazepam exposure (226) 21 oceptor blockade (226) 93 Martin, K.F., see Iredale, P.A. (226) 163 Raghunathan, G., see Cruciani, R.A. (226) 287 Martinez, J., see Galas, M.C. (226) 35 Rajdev, S., see Reynolds, I.J. (226) 53 McGuffin, P., see O’Donovan, M.C. (226) 335 Reber, B.F.X., see Neuhaus, R. (226) 183 Mengod, G., see Pombo-Villar, E. (226) 317 Reilly, T.M., Christ, D.D., Duncia, J.V., Pierce, S.K. and Timmer- Meunier, J.-C., see Polastron, J. (226) 133 mans, P.B.M.W.M. Minneman, K.P., see Han, C. (226) 141 Monoclonal antibodies to the nonpeptide angiotensin II receptor Miyajima, T., see Tsujino, T. (226) 69 antagonist, losartan (226) 179 Miyamoto, A., see Villalobos-Molina, R. (226) 129 Rensing, H., see Jackisch, R. (226) 245 Mohr, C., see Koch, G. (226) 87 Reynolds, I.J., Rothermund, K., Rajdev, S., Faugq, A.H. and Muller, W.E.G., Schroder, H.C., Ushijima, H., Dapper, J. and Bor- Kozikowski, A.P. mann, J. [!*°1]Thienylphencyclidine, a novel ligand for the NMDA recep- gp120 of HIV-1 induces apoptosis in rat cortical cell cultures: tor (226) 53 prevention by memantine (226) 209 Richards, S.J., see Challiss, R.A.J. (226) 121 Muraki, T., Irie, K., Uchida, Y. and Nomoto, T. Richelson, E., see Yamada, M. (226) 187 Developmental changes in the effect of atrial natriuretic peptide Riederer, P., see Gerlach, M. (226) 97 on tissue cyclic GMP content and particulate guanylate cyclase Roques, B.P., see Cheng, J. (226) 15 activity of aorta, kidney and lung of rats (226) 311 Ross, S.B., see Ericson, H. (226) 157 385 Roth, G.S., see Villalobos-Molina, R. (226). 129 Tomura, H., Okajima, F. and Kondo, Y. Rothermund, K., see Reynolds, I.J. (226) 53 Discrimination between two types of P, purinoceptors by suramin in rat hepatocytes (226) 363 Saavedra, J.M., see Tsutsumi, K. (226) 169 Trifiletti, R.R. and Pranzatelli, M.R. Sabra, R. and Branch, R.A. ACTH binds to [*H]MK-801-labelled rat hippocampal NMDA Effect of amphotericin B on intracellular calcium levels in cul- receptors (226) 377 tured glomerular mesangial cells (226) 79 Tsujino, T., Sano, H., Kubota, Y., Hsieh, S.-T., Miyajima, T., Saito, Safrany, S.T., Wilcox, R.A., Liu, C., Potter, B.V.L. and Nahorski, K., Nakajima, M., Saito, N. and Yokoyama, M. S.R. Expression of Fos-like immunoreactivity by yohimbine and cloni- 3-Position modification of myo-inositol 1,4,5-trisphosphate: con- dine in the rat brain (226) 69 sequences for intracellular Ca** mobilisation and enzyme recog- Tsutsumi, K., Zorad, S. and Saavedra, J.M. nition (226) 265 The AT, subtype of the angiotensin II receptors has differential Saito, K., see Tsujino, T. (226) 69 sensitivity to dithiothreitol in specific brain nuclei of young rats Saito, N., see Tsujino, T. (226) 69 (226) 169 Sakai, Y., see Sakuta, H. (226) 199 Sakuta, H., Sekiguchi, M., Okamoto, K. and Sakai, Y. Uchida, Y., see Muraki, T. (226) 311 Inactivation of glibenclamide-sensitive K* channels in Xenopus Umemura, S., see Sun, L. (226) 367 oocytes by various calmodulin antagonists (226) 199 Undie, A.S. and Friedman, E. Sano, H., see Tsujino, T. (226) 69 Selective dopaminergic mechanism of dopamine and SKF38393 Scapagnini, U., see Sortino, M.A. (226) 273 stimulation of inositol phosphate formation in rat brain (226) 297 Schenk, A., see Honscha, W. (226) 215 Ungerer, M., Obermaier-Skrobranek, B. and Lohse, M.J. Schrader, J., see Hartmann, M. (226) 225 Adenosine A, receptor gene structure and regulation in nor- Schroder, H.C., see Miiller, W.E.G. (226) 209 motensive and spontaneously hypertensive rats (226) 381 Schuh, K., see Honscha, W. (226) 215 Ushijima, H., see Miller, W.E.G. (226) 209 Schwindt, P., see Greene, C. (226) 279 Sekiguchi, M., see Sakuta, H. (226) 199 Valliere, J.E., DeLuca, A.W. and Shreeve, S.M. Shreeve, S.M. and Valliere, J.E. Reconstitution of a,-adrenoceptors having high affinity for pra- The a,-adrenoceptor is inactivated by alterations in membrane zosin (226) 191 phospholipids (226) 29 Valliere, J.E., see Shreeve, S.M. (226) 29 Shreeve, S.M., see Valliere, J.E. (226) 191 Van der Bent, A., Ter Laak, A.M., IJzerman, A.P. and Soudijn, W. Sortino, M.A., Aleppo, G., Scapagnini, U. and Canonico, P.L. Molecular modelling of asperlicin derived cholecystokinin A re- Ipriflavone inhibits phosphoinositide hydrolysis and Ca** uptake ceptor antagonists (226) 327 in the osteoblast-like UMR-106 cells (226) 273 Villalobos-Molina, R., Miyamoto, A., Kowatch, M.A. and Roth, G.S. Soskié, V. and Maelicke, A. a,-Adrenoceptors in parotid cells: age does not alter the ratio of Synthesis and characterization of biotinylated and photoactivat- a1, and a;p subtypes (226) 129 able neuroleptics. Novel bifunctional probes for dopamine recep- Villar, H.O., see Maguire, P.A. (226) 233 tors (226) 109 Vrana, O., Kiseleva, V.I., Poverenny, A.M. and Brabec, V. Soudijn, W., see Van der Bent, A. (226) 327 Conversion of DNA adducts of antitumour cis-diammine- Spurlock, G., see O’Donovan, M.C. (226) 335 dichloroplatinum(II). Immunochemical analysis (226) 5 Stanley, E.F., see Cruciani, R.A. (226) 287 Vray, B., see Coquette, A. (226) 1 Sun, L., Umemura, S., Chun, M. and Pettinger, W.A. Northern blot and ribonuclease protection study of a -adrenoc- Wiederhold, K.-H., see Pombo-Villar, E. (226) 317 eptor subtypes in cultured cell lines (226) 367 Wilcox, R.A., see Safrany, $.T. (226) 265 Supavilai, P., see Pombo-Villar, E. (226) 317 Szewczyk, A., De Weille, J.R. and Lazdunski, M. Yamada, M., Yamada, M. and Richelson, E. TMB-8 (8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate) in- Block of neurotensin receptor down-regulation by an aminos- hibits the ATP-sensitive K* channel (226) 175 teroid in N1E-115 cells (226) 187 Yamada, M., see Yamada, M. (226) 187 Tachado, S.D., see Abdel-Latif, A.A. (226) 351 Yokoyama, M., see Tsujino, T. (226) 69 Ter Laak, A.M., see Van der Bent, A. (226) 327 Yoshikami, D., see Hammerland, L.G. (226) 239 Theis, J.G.W., Dellweg, H., Perzborn, E. and GroB, R. Youdim, M.B.H., see Gerlach, M. (226) 97 pH dependency of the binding of [7H]BAY U 3405 and various Yousufzai, S.Y.K., see Abdel-Latif, A.A. (226) 351 non-labelled ligands to the thromboxane A,/prostaglandin H, receptor of human platelet membranes (226) 149 Zasloff, M., see Cruciani, R.A. (226) 287 Timmermans, P.B.M.W.M., see Reilly, T.M. (226) 179 Zorad, S., see Tsutsumi, K. (226) 169 European Journal of Pharmacology — Molecular Pharmacology Section, 226 (1992) 387-395 © 1992 Elsevier Science Publishers B.V. All rights reserved 0922-4106 /92/$05.00 Key word index ACTH Norepinephrine; Ca**; Smooth muscle (Han, C. (226) 141) Myoclonus; Epilepsy; NMDA receptors (Trifiletti, R.R. (226) 377) Electroconvulsive shock; Brain (rat); S-HT, receptors; Phosphoinosi- Adenosine tide hydrolysis (Pandey, G.N. (226) 303) Adenosine receptors; Insulin sensitivity; Glucose transport; Amino acid transport; Skeletal muscle (Challiss, R.A.J. (226) 121) a,-Adrenoceptors Fos; Yohimbine; Clonidine; Guanabenz (Tsujino, T. (226) 69) Adenosine receptors Adenosine; Insulin sensitivity; Glucose transport; Amino acid trans- 8 ,-Adrenoceptors port; Skeletal muscle (Challiss, R.A.J. (226) 121) Amitriptyline; Xerostomia; Cytosolic free Ca**: a ,-Adrenoceptors; Muscarinic acetylcholine receptors; Parotid gland; Salivary glands Adenosine A, receptors (Glenert, U. (226) 43) Polymerase chain reaction; Spontaneously hypertensive rat (SHR) (Ungerer, M. (226) 381) a ,-Adrenoceptor subtypes Parotid cells; Aging (Villalobos-Molina, R. (226) 129) Adenylate cyclase 5-Opioid receptors; NG 108-15 hybrid cell; [*H]Etorphine; [>H]Di- Afterdepolarization prenorphine; 5’-Guanylylimidophosphate (GppNHp); Sucrose gradi- Metabotropic receptors; Glutamate (Greene, C. (226) 279) ents; G-proteins (Polastron, J. (226) 133) Aging Platelets (human); 5-HT (5-hydroxytryptamine, serotonin) (Newman, a,-Adrenoceptor subtypes; Parotid cells (Villalobos-Molina, R. (226) M.E. (226) 281) 129) ADP-ribosyltransferase C3 (Clostridium botulinum) Amino acid transport Guanine nucleotide-binding proteins (small); rho proteins; Melittin; Adenosine; Adenosine receptors; Insulin sensitivity; Glucose trans- Mast cell degranulating peptide; Compound 48/80 (Koch, G. (226) port; Skeletal muscle (Challiss, R.A.J. (226) 121) 87) Amitriptyline a ,-Adrenoceptor Xerostomia; Cytosolic free Ca**; a,-Adrenoceptors; 8 ,-Adrenocep- Membrane lipids; Phospholipases; Phospholipase C; Phospholipids; tors; Muscarinic acetylcholine receptors; Parotid gland; Salivary Aorta (Shreeve, S.M. (226) 29) glands (Glenert, U. (226) 43) B-Adrenoceptor cAMP Calmodulin antagonist; Cromakalim; ATP-sensitive K* channel; Lithium chloride; Norepinephrine; Isoprenaline; Phenoxybenzamine; Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; Propranolol (Marmol, F. (226) 93) Chlorpromazine; Haloperidol; Sulfonylurea; Glibenclamide; cAMP; Isoproterenol (Sakuta, H. (226) 199) Calmodulin antagonist; Cromakalim; ATP-sensitive K~* channel; Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; a,-Adrenoceptor mechanism Chlorpromazine; Haloperidol; Sulfonylurea; Glibenclamide; B- 3,4-Diaminopyridine; Noradrenaline release; Hippocampus; Ca** Adrenoceptor; Isoproterenol (Sakuta, H. (226) 199) (intracellular); (Rat); (Rabbit) (Jackisch, R. (226) 245) Dopamine receptors; Vascular smooth muscle (rat); Mesenteric a,-Adrenoceptor mRNA artery; Thiol group (Hall, A.S. (226) 253) HT29 cells; OK cells; NG108 cells (Sun, L. (226) 367) Iris sphincter (dog); Smooth muscle; Muscarinic stimulation; Inositol a-Adrenoceptors trisphosphate; Ca**; Cross-talk; Contraction-relaxation (Abdel-Latif, Prazosin; Receptor reconstitution; Detergent solubilization; Recep- A.A. (226) 351) tor conformation (Valliere, J.E. (226) 191) cAMP accumulation Dopamine receptors; Inositol phosphates; Phosphoinositides; Stria- Cholecystokinin, CCK, receptors; Synaptoneurosomes (guinea pig, tum (rat); 5-HT receptors (Undie, A.S. (226) 297) cerebral cortex); Boc-[Leu*!]CCK-4 binding; Inositol phosphate ac- cumulation; *°Ca** efflux (Galas, M.C. (226) 35) a ,-Adrenoceptors Amitriptyline; Xerostomia; Cytosolic free Ca’*; B,-Adrenoceptors; Amphotericin B Muscarinic acetylcholine receptors; Parotid gland; Salivary glands Mesangial cells; Ca** (intracellular); Diltiazem; Theophylline (Sabra, (Glenert, U. (226) 43) R. (226) 79) 388 Angiotensin AT, receptor antagonists Benzodiazepine (receptor binding) Angiotensin II; Monoclonal antibodies; Losartan (Reilly, T.M. (226) Thermodynamics; Benzodiazepine receptor (type I); Cerebellum 179) (Maguire, P.A. (226) 233) Angiotensin II Benzodiazepine receptors (peripheral) Angiotensin AT, receptor antagonists; Monoclonal antibodies; Kidney (rat); Angiotensin II (Holmes, P.V. (226) 189) Losartan (Reilly, T.M. (226) 179) Benzodiazepine receptor (type I) Kidney (rat); Benzodiazepine receptors (peripheral) (Holmes, P.V. Benzodiazepine (receptor binding); Thermodynamics; Cerebellum (226) 189) (Maguire, P.A. (226) 233) Angiotensin II receptor subtypes Benzodiazepines AT, receptors; Sulfhydryl reducing agents; Dithiothreitol; Losartan Tolerance; GABA , receptor; mRNA levels; (Rat) (O’Donovan, M.C. (DuP 753); Brain development (Tsutsumi, K. (226) 169) (226) 335) Antibacterial peptide Boc-[Leu*!]CCK-4 binding Artificial bilayer; Ion channel reconstitution; Peptide ion channel Cholecystokinin; CCK, receptors; Synaptoneurosomes (guinea pig, (Cruciani, R.A. (226) 287) cerebral cortex); Inositol phosphate accumulation; cAMP accumula- tion; *Ca?* efflux (Galas, M.C. (226) 35) Aorta a,-Adrenoceptor; Membrane lipids; Phospholipases; Phospholipase Brain development C; Phospholipids (Shreeve, S.M. (226) 29) Angiotensin II receptor subtypes; AT, receptors; Sulfhydryl reducing agents; Dithiothreitol; Losartan (DuP 753) (Tsutsumi, K. (226) 169) Atrial natriuretic peptide (ANP); Guanylate cyclase; Ontogenesis; Kidney; Lung (Muraki, T. (226) 311) Brain (rat) Electroconvulsive shock; a,-Adrenoceptors; 5-HT, receptors; Phos- Apoptosis phoinositide hydrolysis (Pandey, G.N. (226) 303) Human immunodeficiency virus type 1 (HIV-1); Cortical cells; Me- mantine; NMDA receptor; gp120 (Miller, W.E.G. (226) 209) Bumetanide transport Artificial bilayer Loop diuretics; Photoaffinity labeling; Sinusoidal plasma membrane Antibacterial peptide; Ion channel reconstitution; Peptide ion chan- (rat liver); Integral plasma membrane proteins; Two-dimensional gel nel (Cruciani, R.A. (226) 287) electrophoresis (Honscha, W. (226) 215) Ca*+ ATP Suramin; P, purinoceptor; Hepatocytes; (Rat) (Tomura, H. (226) a,-Adrenoceptors; Norepinephrine; Smooth muscle (Han, C. (226) 363) 141) ATP-sensitive K * channel Iris sphincter (dog); Smooth muscle; Muscarinic stimulation; cAMP; Calmodulin antagonist; Cromakalim; Oocyte (Xenopus laevis); W-7; Inositol trisphosphate; Cross-talk; Contraction-relaxation (Abdel- W-5; Phenothiazines; Trifluoperazine; Chlorpromazine; Haloperidol; Latif, A.A. (226) 351) Sulfonylurea; Glibenclamide; cAMP; B-Adrenoceptor; Isoproterenol (Sakuta, H. (226) 199) Ca?+ channel Calmodulin; CGS 9343B; Patch clamp; Fura-2 (Neuhaus, R. (226) ATP-sensitive potassium channel 183) TMB-8 (8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate); B- Cells (Szewezyk, A. (226) 175) Ca?* channel (mammalian, presynaptic) Spider toxin; Glutamate (Pocock, J.M. (226) 343) AT, receptors Angiotensin II receptor subtypes; Sulfhydryl reducing agents; Dithio- 4SCa?* efflux threitol; Losartan (DuP 753); Brain development (Tsutsumi, K. (226) Cholecystokinin; CCK, receptors; Synaptoneurosomes (guinea pig, 169) cerebral cortex); Boc-[Leu*!]CCK-4 binding; Inositol phosphate ac- cumulation; cAMP accumulation (Galas, M.C. (226) 35) Atrial natriuretic peptide (ANP) Guanylate cyclase; Ontogenesis; Aorta; Kidney; Lung (Muraki, T. Ca?*+ (intracellular) (226) 311) Amphotericin B; Mesangial cells; Diltiazem; Theophylline (Sabra, R. (226) 79) BAY U 3405 Thromboxane A; Thromboxane A, receptor antagonist; Thrombox- ane A, receptor agonist; pH dependency; Radioligand binding; 3,4-Diaminopyridine; Noradrenaline release; Hippocampus; a,- Platelet membranes (human) (Theis, J.G.W. (226) 149) Adrenoceptor mechanism; (Rat); (Rabbit) (Jackisch, R. (226) 245) Benzodiazepine Calmodulin Tolerance; GABA, receptor complex (a, subunit; y, subunit; B, Ca**+ channel; CGS 9343B; Patch clamp; Fura-2 (Neuhaus, R. (226) subunit); (Rat) (Primus, R.J. (226) 21) 183) Calmodulin antagonist Clonidine Cromakalim; ATP-sensitive K* channel; Oocyte (Xenopus laevis); Fos; a,-Adrenoceptors; Yohimbine; Guanabenz (Tsujino, T. (226) W-7; W-5; Phenothiazines; Trifluoperazine; Chlorpromazine; 69) Haloperidol; Sulfonylurea; Glibenclamide; cAMP; B-Adrenoceptor; Isoproterenol (Sakuta, H. (226) 199) Compound 48 / 80 Guanine nucleotide-binding proteins (small); rho proteins; ADP- Ca** mobilization ribosyltransferase C3 (Clostridium botulinum); Melittin; Mast cell Second messenger; Inositdl phosphate analogues (Safrany, S.T. (226) degranulating peptide (Koch, G. (226) 87) 265) Conantokin NMDA receptor; Oocytes (Xenopus) (Hammerland, L.G. (226) 239) 4SCa?* uptake Ipriflavone; Phosphoinositides; UMR-106 cells (Sortino, M.A. (226) Contraction-relaxation 273) Iris sphincter (dog); Smooth muscle; Muscarinic stimulation; cAMP; Inositol trisphosphate; Ca?*; Cross-talk (Abdel-Latif, A.A. (226) CCK, receptor antagonists 351) Cholecystokinin receptor; Molecular modelling; Devazepide; L- 364,718 (Van der Bent, A. (226) 327) Cortical cells Human immunodeficiency virus type 1 (HIV-1); Apoptosis; Meman- CCK, receptors tine; NMDA receptor; gp120 (Miiller, W.E.G. (226) 209) Cholecystokinin; Synaptoneurosomes (guinea pig, cerebral cortex); Boc-[Leu*! ]CCK-4 binding; Inositol phosphate accumulation; cAMP Cromakalim accumulation; *°Ca?* efflux (Galas, M.C. (226) 35) Calmodulin antagonist; ATP-sensitive K* channel; Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; Chlorpromazine; Cell culture Haloperidol; Sulfonylurea; Glibenclamide; cAMP; B-Adrenoceptor; Ifenprodil; Neurotoxicity; NMDA receptors (Graham, D. (226) 373) Isoproterenol (Sakuta, H. (226) 199) Cross-talk B-Cells Iris sphincter (dog); Smooth muscle; Muscarinic stimulation; cAMP; TMB-8 (8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate); ATP- sensitive potassium channel (Szewcezyk, A. (226) 175) Inositol trisphosphate; Ca?*: Contraction-relaxation (Abdel-Latif, A.A. (226) 351) Cerebellum CRI receptors Benzodiazepine (receptor binding); Thermodynamics; Benzodi- Peritoneal cells (rat); Phagocytosis (bacterial); Eicosanoids; In- azepine receptor (type I) (Maguire, P.A. (226) 233) domethacin; Fc receptors (Coquette, A. (226) 1) Cerebral cortex (rat) Cultured cells Ouabain binding site (high affinity); Melatonin; [*H]Ouabain Cisplatin; Pt-DNA adducts; Enzyme-linked immunosorbent assay (Acuna Castroviejo, D. (226) 59) (ELISA); Epitope (Vrana, O. (226) 5) c-fos expression Cytosolic free Ca2* Muscarinic receptor subtypes; Muscarinic receptor agonists; Stereo- Amitriptyline; Xerostomia; a@,-Adrenoceptors; £6,-Adrenoceptors; chemistry (absolute); Superior cervical ganglion (rat); Hippocampal Muscarinic acetylcholine receptors; Parotid gland; Salivary glands slice (rat); Ileum (guinea pig); Hybridization (in situ) (Pombo- Villar, (Glenert, U. (226) 43) E. (226) 317) L-Deprenyl CGS 9343B Monoamine oxidase inhibitors; Parkinson’s disease; Neuroprotective Ca** channel; Calmodulin; Patch clamp; Fura-2 (Neuhaus, R. (226) mechanisms (Gerlach, M. (226) 97) 183) Detergent solubilization a-Adrenoceptors; Prazosin; Receptor reconstitution; Receptor con- Chlorpromazine formation (Valliere, J.E. (226) 191) Calmodulin antagonist; Cromakalim; ATP-sensitive K* channel; Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; Devazepide Haloperidol; Sulfonylurea; Glibenclamide; cAMP; B-Adrenoceptor; Cholecystokinin receptor; CCK, receptor antagonists; Molecular Isoproterenol (Sakuta, H. (226) 199) modelling; L-364,718 (Van der Bent, A. (226) 327) Cholecystokinin 3,4-Diaminopyridine CCK , receptors; Synaptoneurosomes (guinea pig, cerebral cortex); Noradrenaline release; Hippocampus; Ca** (intracellular); a@>- Boc-[Leu*! ]CCK-4 binding; Inositol phosphate accumulation; cAMP Adrenoceptor mechanism; (Rat); (Rabbit) (Jackisch, R. (226) 245) accumulation; *°Ca?* efflux (Galas, M.C. (226) 35) Diltiazem Cholecystokinin receptor Amphotericin B; Mesangial cells; Ca?* (intracellular); Theophylline CCK, receptor antagonists; Molecular modelling; Devazepide; L- (Sabra, R. (226) 79) 364,718 (Van der Bent, A. (226) 327) [3H] Diprenorphine Cisplatin 5-Opioid receptors; NG 108-15 hybrid cell; [*HJEtorphine; 5’- Pt-DNA adducts; Enzyme-linked immunosorbent assay (ELISA); Guanylylimidophosphate (GppNHp); Sucrose gradients; Adenylate Epitope; Cultured cells (Vrana, O. (226) 5) cyclase; G-proteins (Polastron, J. (226) 133) 390 Dithiothreitol GABA, receptor complex (a, subunit; y, subunit; 8, subunit) Angiotensin II receptor subtypes; AT, receptors; Sulfhydryl reducing Benzodiazepine; Tolerance; (Rat) (Primus, R.J. (226) 21) agents; Losartan (DuP 753); Brain development (Tsutsumi, K. (226) 169) Glibenclamide Calmodulin antagonist; Cromakalim; ATP-sensitive K* channel; Dopamine receptors Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; cAMP; Vascular smooth muscle (rat); Mesenteric artery; Thiol group Chlorpromazine; Haloperidol; Sulfonylurea; cAMP; 6-Adrenocep- (Hall, A.S. (226) 253) tor; Isoproterenol (Sakuta, H. (226) 199) Inositol phosphates; Phosphoinositides; Striatum (rat); a-Adreno- Glucose transport ceptors; 5-HT receptors (Undie, A.S. (226) 297) Adenosine; Adenosine receptors; Insulin sensitivity; Amino acid transport; Skeletal muscle (Challiss, R.A.J. (226) 121) Dopamine D, receptors Q Dopamine D, receptors (Soski¢, V. (226) 109) Glutamate Metabotropic receptors; Afterdepolarization (Greene, C. (226) 279) Dopamine D, receptors — Dopamine D, receptors (Soski¢, V. (226) 109) Spider toxin; Ca** channel (mammalian, presynaptic) (Pocock, J.M. (226) 343) Down-regulation gp120 Neurotensin receptors; U-73122 (Yamada, M. (226) 187) Human immunodeficiency virus type 1 (HIV-1); Apoptosis; Cortical cells; Memantine; NMDA receptor (Miiller, W.E.G. (226) 209) Eicosanoids Peritoneal cells (rat); Phagocytosis (bacterial); Indomethacin; CR1 G-proteins receptors; Fc receptors (Coquette, A. (226) 1) 5-Opioid receptors; NG 108-15 hybrid cell; [*H]Etorphine; [*H]Di- prenorphine; 5’-Guanylylimidophosphate (GppNHp); Sucrose gradi- Electroconvulsive shock ents; Adenylate cyclase (Polastron, J. (226) 133) Brain (rat); a@,-Adrenoceptors; 5-HT, receptors; Phosphoinositide hydrolysis (Pandey, G.N. (226) 303) Guanabenz Fos; a,-Adrenoceptors; Yohimbine; Clonidine (Tsujino, T. (226) 69) Endothelin-1 Inositol 1,4,5-trisphosphate; Protein kinase C; Flosequinan (Lang, D. Guanine nucleotide-binding proteins (small) (226) 259) rho proteins; ADP-ribosyltransferase C3 (Clostridium botulinum); Melittin; Mast cell degranulating peptide; Compound 48/80 (Koch, Enzyme-linked immunosorbent assay (ELISA) G. (226) 87) Cisplatin; Pt-DNA adducts; Epitope; Cultured cells (Vrana, O. (226) 5) Guanylate cyclase Atrial natriuretic peptide (ANP); Ontogenesis; Aorta; Kidney; Lung Epilepsy (Muraki, T. (226) 311) ACTH; Myoclonus; NMDA receptors (Trifiletti, R.R. (226) 377) 5’-Guanylylimidophosphate (GppNHp) Epitope 5-Opioid receptors; NG 108-15 hybrid cell; [*H]Etorphine; [*>H]Di- Cisplatin; Pt-DNA adducts; Enzyme-linked immunosorbent assay prenorphine; Sucrose gradients; Adenylate cyclase; G-proteins (ELISA); Cultured cells (Vrana, O. (226) 5) (Polastron, J. (226) 133) [3H] Etorphine Haloperidol 5-Opioid receptors; NG 108-15 hybrid cell; [*H]Diprenorphine; 5’- Remoxipride; o Recognition sites (Ericson, H. (226) 157) Guanylylimidophosphate (GppNHp); Sucrose gradients; Adenylate cyclase; G-proteins (Polastron, J. (226) 133) Calmodulin antagonist; Cromakalim; ATP-sensitive K* channel; Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; Fc receptors Chlorpromazine; Sulfonylurea; Glibenclamide; cAMP; $-Adrenoc- Peritoneal cells (rat); Phagocytosis (bacterial); Eicosanoids; In- eptor; Isoproterenol (Sakuta, H. (226) 199) domethacin; CR1 receptors (Coquette, A. (226) 1) Heart Flosequinan Protein kinase C; Protein (15 kDa); Phospholamban (Hartmann, M. Endothelin-1; Inositol 1,4,5-trisphosphate; Protein kinase C (Lang, (226) 225) D. (226) 259) Hepatocytes Fos Suramin; ATP; P, purinoceptor; (Rat) (Tomura, H. (226) 363) a,-Adrenoceptors; Yohimbine; Clonidine; Guanabenz (Tsujino, T. (226) 69) Hippocampal slice (rat) Muscarinic receptor subtypes; Muscarinic receptor agonists; Stereo- Fura-2 chemistry (absolute); Superior cervical ganglion (rat); Ileum (guinea Ca?* channel; Calmodulin; CGS 9343B; Patch clamp (Neuhaus, R. pig); c-fos expression; Hybridization (in situ) (Pombo-Villar, E. (226) (226) 183) 317) GABA , receptor Hippocampus Benzodiazepines; Tolerance; mRNA levels; (Rat) (O’Donovan, M.C. 3,4-Diaminopyridine; Noradrenaline release; Ca”* (intracellular); (226) 335) a,-Adrenoceptor mechanism; (Rat); (Rabbit) (Jackisch, R. (226) 245) HT29 cells Ion channel reconstitution a,-Adrenoceptor mRNA; OK cells; NG108 cells (Sun, L. (226) 367) Antibacterial peptide; Artificial bilayer; Peptide ion channel (Cruciani, R.A. (226) 287) 5-HT (5-hydroxytryptamine, serotonin) Adenylate cyclase; Platelets (human) (Newman, M.E. (226) 281) Ipriflavone Phosphoinositides; UMR-106 cells; “*Ca** uptake (Sortino, M.A. 5-HT receptors (226) 273) Dopamine receptors; Inositol phosphates; Phosphoinositides; Stria- Iris sphincter (dog) tum (rat); a-Adrenoceptors (Undie, A.S. (226) 297) Smooth muscle; Muscarinic stimulation; cAMP; Inositol trisphos- phate; Ca**; Cross-talk; Contraction-relaxation (Abdel-Latif, A.A. 5-HT, receptors (226) 351) Electroconvulsive shock; Brain (rat); a,-Adrenoceptors; Phospho- inositide hydrolysis (Pandey, G.N. (226) 303) Isoprenaline Lithium chloride; cAMP; Norepinephrine; Phenoxybenzamine; Pro- Human immunodeficiency virus type 1 (HIV-1) pranolol (Marmol, F. (226) 93) Apoptosis; Cortical cells; Memantine; NMDA receptor; gp120 (Miller, W.E.G. (226) 209) Isoproterenol Calmodulin antagonist; Cromakalim; ATP-sensitive K* channel; Hybridization (in situ) Oocyte (Xenopus laevis); W-7; W-5; Phenothiazines; Trifluoperazine; Muscarinic receptor subtypes; Muscarinic receptor agonists; Stereo- Chlorpromazine; Haloperidol; Sulfonylurea; Glibenclamide; cAMP; chemistry (absolute); Superior cervical ganglion (rat); Hippocampal B-Adrenoceptor (Sakuta, H. (226) 199) slice (rat); Ileum (guinea pig); c-fos expression (Pombo-Villar, E. (226) 317) Kidney Atrial natriuretic peptide (ANP); Guanylate cyclase; Ontogenesis; Ifenprodil Aorta; Lung (Muraki, T. (226) 311) Neurotoxicity; Cell culture; NMDA receptors (Graham, D. (226) 373) Kidney (rat) Benzodiazepine receptors (peripheral); Angiotensin II (Holmes, P.V. Ileum (guinea pig) (226) 189) Muscarinic receptor subtypes; Muscarinic receptor agonists; Stereo- L-364,718 chemistry (absolute); Superior cervical ganglion (rat); Hippocampal Cholecystokinin receptor; CCK, receptor antagonists; Molecular slice (rat); c-fos expression; Hybridization (in situ) (Pombo-Villar, E. modelling; Devazepide (Van der Bent, A. (226) 327) (226) 317) © Lithium chloride Indomethacin cAMP; Norepinephrine; Isoprenaline; Phenoxybenzamine; Propra- Peritoneal cells (rat); Phagocytosis (bacterial); Eicosanoids; CR1 nolol (Marmol, F. (226) 93) receptors; Fc receptors (Coquette, A. (226) 1) Loop diuretics Inositol phosphate accumulation Bumetanide transport; Photoaffinity labeling; Sinusoidal plasma Cholecystokinin, CCK, receptors; Synaptoneurosomes (guinea pig, membrane (rat liver); Integral plasma membrane proteins; Two-di- cerebral cortex); Boc-[Leu*!]CCK-4 binding; cAMP accumulation; mensional gel electrophoresis (Honscha, W. (226) 215) SCa?* efflux (Galas, M.C. (226) 35) Losartan Inositol phosphate analogues Angiotensin II; Angiotensin AT, receptor antagonists; Monoclonal Second messenger; Ca** mobilization (Safrany, S.T. (226) 265) antibodies (Reilly, T.M. (226) 179) Losartan (DuP 753) Inositol phosphates Angiotensin II receptor subtypes; AT, receptors; Sulfhydryl reducing Dopamine receptors; Phosphoinositides; Striatum (rat); a-Adreno- ceptors; 5-HT receptors (Undie, A.S. (226) 297) agents; Dithiothreitol; Brain development (Tsutsumi, K. (226) 169) Lung Inositol trisphosphate Atrial natriuretic peptide (ANP); Guanylate cyclase; Ontogenesis; Iris sphincter (dog); Smooth muscle; Muscarinic stimulation; cAMP; Aorta; Kidney (Muraki, T. (226) 311) Ca**; Cross-talk; Contraction-relaxation (Abdel-Latif, A.A. (226) 351) Mast cell degranulating peptide Guanine nucleotide-binding proteins (small); rho proteins; ADP- Inositol 1,4,5-trisphosphate ribosyltransferase C3 (Clostridium botulinum); Melittin; Compound Endothelin-1; Protein kinase C; Flosequinan (Lang, D. (226) 259) 48 /80 (Koch, G. (226) 87) Insulin sensitivity Melatonin Adenosine; Adenosine receptors; Glucose transport; Amino acid Ouabain binding site (high affinity); [*H]Ouabain; Cerebral cortex transport; Skeletal muscle (Challiss, R.A.J. (226) 121) (rat) (Acuna Castroviejo, D. (226) 59) Integral plasma membrane proteins Melittin Bumetanide transport; Loop diuretics; Photoaffinity labeling; Sinu- Guanine nucleotide-binding proteins (small); rho proteins; ADP- soidal plasma membrane (rat liver); Two-dimensional gel elec- ribosyltransferase C3 (Clostridium botulinum); Mast cell degranulat- trophoresis (Honscha, W. (226) 215) ing peptide; Compound 48/80 (Koch, G. (226) 87) 392 Memantine Neurotoxicity Human immunodeficiency virus type 1 (HIV-1); Apoptosis; Cortical Ifenprodil; Cell culture; NMDA receptors (Graham, D. (226) 373) cells; NMDA receptor; gp120 (Miiller, W.E.G. (226) 209) NG108 cells Membrane lipids a,-Adrenoceptor mRNA; HT29 cells; OK cells (Sun, L. (226) 367) a,-Adrenoceptor; Phospholipases; Phospholipase C; Phospholipids; Aorta (Shreeve, S.M. (226) 29) NG 108-15 hybrid cell 5-Opioid receptors; [7H]Etorphine; [*H]Diprenorphine; 5’-Guanyl- Mesangial cells ylimidophosphate (GppNHp); Sucrose gradients; Adenylate cyclase; Amphotericin B; Ca’** (intracellular); Diltiazem; Theophylline G-proteins (Polastron, J. (226) 133) (Sabra, R. (226) 79) NMDA receptor [!>1]Thienylphencyclidine; Polyamines (Reynolds, I.J. (226) 53) Mesenteric artery cAMP; Dopamine receptors; Vascular smooth muscle (rat); Thiol group (Hall, A.S. (226) 253) Human immunodeficiency virus type 1 (HIV-1); Apoptosis; Cortical cells; Memantine; gp120 (Miiller, W.E.G. (226) 209) Metabotropic receptors Glutamate; Afterdepolarization (Greene, C. (226) 279) Oocytes (Xenopus) ;C onantokin (Hammerland, L.G. (226) 239) Molecular modelling NMDA receptors Cholecystokinin receptor; CCK, receptor antagonists; Devazepide; Ifenprodil; Neurotoxicity; Cell culture (Graham, D. (226) 373) L-364,718 (Van der Bent, A. (226) 327) ACTH; Myoclonus; Epilepsy (Trifiletti, R.R. (226) 377) Monoamine oxidase inhibitors Parkinson’s disease; L-Deprenyl; Neuroprotective mechanisms Noradrenaline release (Gerlach, M. (226) 97) 3,4-Diaminopyridine; Hippocampus; Ca’* (intracellular); a,-Adren- oceptor mechanism; (Rat); (Rabbit) (Jackisch, R. (226) 245) Monoclonal antibodies Angiotensin II; Angiotensin AT, receptor antagonists; Losartan Norepinephrine (Reilly, T.M. (226) 179) Lithium chloride; cAMP; Isoprenaline; Phenoxybenzamine; Propra- nolol (Marmol, F. (226) 93) Morphine k-Opioid receptor; Naloxone benzoylhydrazone (Cheng, J. (226) 15) a ,-Adrenoceptors; Ca**; Smooth muscle (Han, C. (226) 141) Muscarinic acetylcholine receptors OK cells Amitriptyline; Xerostomia; Cytosolic free Ca?*; a,-Adrenoceptors; a,-Adrenoceptor mRNA; HT29 cells; NG108 cells (Sun, L. (226) B,-Adrenoceptors; Parotid gland; Salivary glands (Glenert, U. (226) 367) 43) Ontogenesis Muscarinic receptor agonists Atrial natriuretic peptide (ANP); Guanylate cyclase; Aorta; Kidney; Muscarinic receptor subtypes; Stereochemistry (absolute); Superior Lung (Muraki, T. (226) 311) cervical ganglion (rat); Hippocampal slice (rat); Ileum (guinea pig); c-fos expression; Hybridization (in situ) (Pombo-Villar, E. (226) 317) Oocytes (Xenopus) NMDA receptor; Conantokin (Hammerland, L.G. (226) 239) Muscarinic receptor subtypes Muscarinic receptor agonists; Stereochemistry (absolute); Superior Oocyte (Xenopus laevis) cervical ganglion (rat); Hippocampal slice (rat); Ileum (guinea pig); Calmodulin antagonist; Cromakalim; ATP-sensitive K* channel; c-fos expression; Hybridization (in situ) (Pombo-Villar, E. (226) 317) W-7; W-5; Phenothiazines; Trifluoperazine; Chlorpromazine; Haloperidol; Sulfonylurea; Glibenclamide; cAMP; B-Adrenoceptor; Muscarinic stimulation Isoproterenol (Sakuta, H. (226) 199) Iris sphincter (dog); Smooth muscle; cAMP; Inositol trisphosphate; Ca?*; Cross-talk; Contraction-relaxation (Abdel-Latif, A.A. (226) «-Opioid receptor 351) Naloxone benzoylhydrazone; Morphine (Cheng, J. (226) 15) Myoclonus 5-Opioid receptors ACTH; Epilepsy; NMDA receptors (Trifiletti, R.R. (226) 377) NG 108-15 hybrid cell; [*HJEtorphine; [*H]Diprenorphine; 5’- Guanylylimidophosphate (GppNHp); Sucrose gradients; Adenylate Naloxone benzoylhydrazone cyclase; G-proteins (Polastron, J. (226) 133) k-Opioid receptor; Morphine (Cheng, J. (226) 15) [7H]O uabain Neuroprotective mechanisms Ouabain binding site (high affinity); Melatonin; Cerebral cortex (rat) Monoamine oxidase inhibitors; Parkinson’s disease; L-Deprenyl (Acuna Castroviejo, D. (226) 59) (Gerlach, M. (226) 97) Ouabain binding site (high affinity) Neurotensin receptors Melatonin; [*H]Ouabain; Cerebral cortex (rat) (Acufia Castroviejo, Down-regulation; U-73122 (Yamada, M. (226) 187) D. (226) 59)

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