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European Journal of Pharmacology 1997: Vol 333 Index PDF

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Preview European Journal of Pharmacology 1997: Vol 333 Index

co European Journal of Pharmacology 333 (1997) 293-295 Author index Abe, Y., see Inamura, N. (333) 79 Diaz, A., Mayet, S. and Dickenson, A.H. Abiko, Y., see Chen, M. (333) 261 BU-224 produces spinal antinociception as an agonist at imidazoline Ahmad, S. I, receptors (333) 9 Angiotensin receptor antagonists delay nitric oxide-deficient stroke in Dickenson, A.H., see Diaz, A. (333) 9 stroke-prone rats (333) 39 Doak, GJ., see Sawynok, J. (333) | Anton, F., see Cortijo, J. (333) 69 D’Orléans-Juste, P., see Berthiaume, N. (333) 55 Aoba, A., see Miyamoto, S. (333) 279 Duridanova, D.B., Gagov, H.S. and Boev, K.K. Araki, T., see Ishizaki, K. (333) 207 Two populations of smooth muscle cells in the guinea-pig gastric Asai, T., see Matsushima, S. (333) 93 antrum (333) 105 Asaka, T., see Inoue, H. (333) 231 Asakura, M., see Miyamoto, S. (333) 279 Ebert, B., Mikkelsen, S., Thorkildsen, C. and Borgbjerg, F.M. Asano, M., see Inamura, N. (333) 79 Norketamine, the main metabolite of ketamine, is a non-competitive Aslan, N., Gren, Z., Onat, F. and Oktay, §. NMDA receptor antagonist in the rat cortex and spinal cord (333) 99 Carbachol-induced pressor responses and muscarinic M, receptors in Eto, T., see Khan, A.1. (333) 187 the central nucleus of amygdala in conscious rats (333) 63 Aura, J., Sirvié, J. and Riekkinen Jr., P. Fournier, A., see Pheng, L.H. (333) R3 Methoctramine moderately improves memory but pirenzepine disrupts Fu, M.L.X., see Skomedal, T. (333) 169 performance in delayed non-matching to position test (333) 129 Fujita, H., see Kageyama, M. (333) 223 Autelitano, F., see Weill, C. (333) 269 Fujiwara, T., see Inamura, N. (333) 79 Gagov, H.S., see Duridanova, D.B. (333) 105 Badran, S., Schmutz, M. and Olpe, H.-R. Giuliani, S., Tramontana, M., Lecci, A. and Maggi, C.A. Comparative in vivo and in vitro studies with the potent GABA, Effect of nociceptin on heart rate and blood pressure in anaesthetized receptor antagonist, CGP 56999A (333) 135 rats (333) 177 Berthiaume, N., Hess, F., Chen, A., Regoli, D. and D’Orléans-Juste, P. Goeldner, M., see Weill, C. (333) 269 Pharmacology of kinins in the arterial and venous mesenteric bed of Gordon, FJ., see Patterson, A.B. (333) 47 normal and B, knockout transgenic mice (333) 55 Giren, Z., see Aslan, N. (333) 63 Berto, L., see Cortijo, J. (333) 69 Goto, W., see Kageyama, M. (333) 223 Bodaiji, N., see Miyamoto, S. (333) 279 Boev, K.K., see Duridanova, D.B. (333) 105 Grau, M., see Cortijo, J. (333) 69 Gualix, J., see Hoyle, C.H.V. (333) RI Bone, H.-G., see Waurick, R. (333) 181 Guenet, C., see Weill, C. (333) 269 Booke, M., see Waurick, R. (333) 181 Borgbjerg, F.M., see Ebert, B. (333) 99 Gyérgy, K., see Vegh, A. (333) 33 Bosker, F.J., Klompmakers, A. and Westenberg, H.G.M. Haniuda, K., Nakane, T. and Chiba, S. Postsynaptic 5-HT,, receptors mediate 5-hydroxytryptamine release Different contributions of ATP and noradrenaline to neurotransmis- in the amygdala through a feedback to the caudal linear raphe (333) sion in the isolated canine intermediate auricular artery (333) 163 147 Hashizume, H., see Chen, M. (333) 261 Hatori, C., see Inamura, N. (333) 79 Carrasco, E., see Cortijo, J. (333) 69 Heitz, F., see Weill, C. (333) 269 Chariot, J., see Souli, A. (333) 87 Hess, F., see Berthiaume, N. (333) 55 Chen, A., see Berthiaume, N. (333) 55 Hirabayashi, N., see Ishizaki, K. (333) 207 Chen, M., Xiao, C.-Y., Hashizume, H. and Abiko, Y. Hirosumi, J., see Inamura, N. (333) 79 Differential effects of Ca** channel blockers on Ca’* overload Hjalmarson, A., see Skomedal, T. (333) 169 induced by lysophosphatidylicholine in cardiomyocytes (333) 261 Hoebeke, J., see Skomedal, T. (333) 169 Chiba, S., see Haniuda, K. (333) 163 Holtzman, S.G., see Patterson, A.B. (333) 47 Cortijo, J., Marti-Cabrera, M., Berto, L., Antén, F., Carrasco, E., Grau, Hoyle, C.H.V., Pintor, J., Gualix, J. and Miras-Portugal, M.T. M. and Morcillo, EJ. Antagonism of P2X receptors in guinea-pig vas deferens by diinosine Pharmacological activity of PF-904 in guinea pig in vivo, and on pentaphosphate (333) R1 human bronchus and neutrophils in vitro (333) 69 Curzon, G., see Datla, K.P. (333) 27 llien, B., see Weill, C. (333) 269 Imafuku, J., see Miyamoto, S. (333) 279 Dahl, R., see Thirstrup, S. (333) 215 Inada, H., see Matsushima, S. (333) 93 Datla, K.P. and Curzon, G. Inamura, N., Asano, M., Hatori, C., Sawai, H., Hirosumi, J., Fujiwara, T.. The effect of p-fenfluramine on brain 5-hydroxytryptamine and 5-hy- Kayakiri, H., Satoh, S., Abe, Y., Inoue, T., Sawada, Y., Oku, T. and droxyindoleacetic acid in male and female rats (333) 27 Nakahara, K. 294 Author index Pharmacological characterization of a novel, orally active, nonpeptide Nagata, N., see Inoue, H. (333) 231 bradykinin B, receptor antagonist, FR167344 (333) 79 Nagatani, T., see Takao, K. (333) 123 Inoue, H., Asaka, T., Nagata, N. and Koshihara, Y. Naka, M., see Matsushima, S. (333) 93 Mechanism of mustard oil-induced skin inflammation in mice (333) Nakahara, K., see Inamura, N. (333) 79 231 Nakane, T., see Haniuda, K. (333) 163 Inoue, T., see Inamura, N. (333) 79 Nakata, K., see Kageyama, M. (333) 223 Ishiguro, I., see Nishida, K. (333) 289 Nasu, T. and Shibata, A. Ishiyama, Y., see Khan, A.I. (333) 187 Na*-independent glucose utilization during Mn**-induced contrac- Ishizaki, K., Kinbara, S., Miyazawa, N., Takeuchi, Y., Hirabayashi, N.., tion in ileal longitudinal smooth muscle (333) 199 Kasai, H. and Araki, T. Nielsen-Kudsk, F., see Thirstrup, S. (333) 215 Effect of sodium tauroursodeoxycholate (UR-906) on liver dysfunc- Nishida, K., Ohta, Y. and Ishiguro, I. tion in bile duct-ligated rats (333) 207 Glycine facilitates y-glutamylcysteinylethy! ester-mediated increase in lyengar, S., see Pheng, L.H. (333) R3 liver glutathione level (333) 289 Kageyama, M., Fujita, H., Goto, W., Nakata, K., Shirasawa, E. and Ohta, Y., see Nishida, K. (333) 289 Kanai, A. Oktay, §., see Aslan, N. (333) 63 FK506-binding proteins regulate smooth muscle contractility by alter- Oku, T., see Inamura, N. (333) 79 ing neurotransmitter release (333) 223 Olpe, H.-R., see Badran, S. (333) 135 Kanai, A., see Kageyama, M. (333) 223 Onat, F., see Aslan, N. (333) 63 Kangawa, K., see Khan, A.1. (333) 187 Osada, K., see Miyamoto, S. (333) 279 Kasai, H., see Ishizaki, K. (333) 207 Osnes, J.-B., see Skomedal, T. (333) 169 Kaszala, K., see Vegh, A. (333) 33 Kato, J., see Khan, A.I. (333) 187 Papp, J.G., see Vegh, A. (333) 33 Katsube, Y., see Yokoshiki, H. (333) 249 Parratt, J.R., see Vegh, A. (333) 33 Kayakiri, H., see Inamura, N. (333) 79 Patterson, A.B., Gordon, FJ. and Holtzman, S.G. Kendall, D.A., see Randall, M.D. (333) 191 Naltrindole, a selective 5-opioid receptor antagonist, potentiates the Khan, A.L., Kato, J., Ishiyama, Y., Kitamura, K., Kangawa, K. and Eto, lethal effects of cocaine by a central mechanism of action (333) 47 1 2 Pézzola, A., see Popoli, P. (333) 143 Effect of chronically infused adrenomedullin in two-kidney, one-clip Pheng, L.H., Quirion, R., lyengar, S., Fournier, A. and Regoli, D. hypertensive rats (333) 187 The rabbit ileum: A sensitive and selective preparation for the neu- Kinbara, S., see Ishizaki, K. (333) 207 ropeptide Y Y, receptor (333) R3 Kitamura, K., see Khan, A.I. (333) 187 Pintor, J., see Hoyle, C.H.V. (333) RI Kitamura, Y., see Takao, K. (333) 123 Popoli, P., Reggio, R. and Pézzola, A. Klompmakers, A., see Bosker, F.J. (333) 147 Adenosine A, and A, receptor agonists significantly prevent the Koshihara, Y., see Inoue, H. (333) 231 electroencephalographic effects induced by MK-801 in rats (333) 143 Kubova, H., Vilagi, I., Mikuleck4, A. and Mare, P. Presset, O., see Souli, A. (333) 87 Non-NMDA receptor antagonist GYKI 52466 suppresses cortical Prien, T., see Waurick, R. (333) 181 afterdischarges in immature rats (333) 17 Quirion, R., see Pheng, L.H. (333) R3 Leander, J.D., see Wolff, M.C. (333) 113 Lecci, A., see Giuliani, S$. (333) 177 Randall, M.D., McCulloch, A.I. and Kendall, D.A. Lin, R.-H., see Liu, S.-H. (333) 241 Comparative pharmacology of endothelium-derived hyperpolarizing Lin-Shiau, S.-Y., see Liu, S.-H. (333) 241 factor and anandamide in rat isolated mesentery (333) 191 Liu, S.-H., Sheu, Z.-J., Lin, R.-H. and Lin-Shiau, S.-Y. Reggio, R., see Popoli, P. (333) 143 The in vivo effect of lipopolysaccharide on neuromuscular transmis- Regoli, D., see Berthiaume, N. (333) 55 sion in the mouse (333) 241 Regoli, D., see Pheng, L.H. (333) R3 Reid, A.R., see Sawynok, J. (333) | Maggi, C.A., see Giuliani, S$. (333) 177 Riekkinen Jr., P., see Aura, J. (333) 129 MareS, P., see Kubova, H. (333) 17 Rozé, C., see Souli, A. (333) 87 Marti-Cabrera, M., see Cortijo, J. (333) 69 Ruiz-Ortega, J.A. and Ugedo, L. Matsushima, S., Inada, H., Asai, T., Naka, M. and Tanaka, T. Activation of 5-HT,, receptors potentiates the clonidine inhibitory Propiverine hydrochloride, an anti-pollakiuric agent, inhibits the activ- effect in the locus coeruleus (333) 159 ity of actomyosin ATPase from the urinary bladder (333) 93 Mayet, S., see Diaz, A. (333) 9 Sasuga, Y., see Miyamoto, S. (333) 279 McCulloch, A.I., see Randall, M.D. (333) 191 Satoh, S., see Inamura, N. (333) 79 MeiBner, A., see Waurick, R. (333) 181 Sawada, Y., see Inamura, N. (333) 79 Meyer, J., see Waurick, R. (333) 181 Sawai, H., see Inamura, N. (333) 79 Mikkelsen, S., see Ebert, B. (333) 99 Sawynok, J., Zarrindast, M.-R., Reid, A.R. and Doak, G.J. Mikulecka, A., see Kubova, H. (333) 17 Adenosine A , receptor activation produces nociceptive behaviour and Miras-Portugal, M.T., see Hoyle, C.H.V. (333) R1 edema by release of histamine and 5-hydroxytryptamine (333) | Miyamoto, S., Asakura, M., Sasuga, Y., Osada, K., Bodaiji, N., Imafuku, Schiander, 1.G., see Skomedal, T. (333) 169 J. and Aoba, A. Schmutz, M., see Badran, S. (333) 135 Effects of long-term treatment with desipramine on microtubule pro- Sheu, Z.-J., see Liu, S.-H. (333) 241 teins in rat cerebral cortex (333) 279 Shibata, A., see Nasu, T. (333) 199 Miyazawa, N., see Ishizaki, K. (333) 207 Shirasawa, E., see Kageyama, M. (333) 223 Morcillo, E.J., see Cortijo, J. (333) 69 Sirvié, J., see Aura, J. (333) 129 Author index Skomedal, T., Fu, M.L.X., Hjalmarson, A., Hoebeke, J., Schiander, LG Vegh, A.. Papp, J.G., GyGrgy, K.. Kaszala, K. and Parratt, J.R. and Osnes, J.-B. Does the opening of ATP-sensitiveK * chanmodnifye islchasemi a- Anti-M, muscarinic receptor antibodies inhibit B-adrenoceptor-medi- induced ventricular arrhythmias in anaesthetised dogs? (333) 33 ated inotropic response in rat myocardium (333) 169 Vilégi, 1., see Kubové, H. (333) 17 Souli, A., Chariot, J., Presset, O., Tsocas, A. and Rozé, C. Neural modulation of the antisecretory effect of peptide YY in the rat Waurick, R., Bone, H.-G., Meyer, J., Booke, M., Meifner, A., Prien, T. jejunum (333) 87 and Van Aken, H. Sperelakis, N., see Yokoshiki, H. (333) 249 Haemodynamic effects of dopexamine and nitric oxide synthase Sunagawa, M., see Yokoshiki, H. (333) 249 inhibition in healthy and endotoxaemic sheep (333) 181 Weill, C., Autelitano, F., Guenet, C., Heitz, F_. Goeldner, M. and Hien, B. Takao, K., Nagatani, T., Kitamura, Y. and Yamawaki, S. Pharmanad sctructourall inotegrgity iof cmuscaarilnic M, acetyl- Effects of corticosterone on 5-HT,, and 5-HT, receptor binding and choline receptors produced in Sf9 insect cells (333) 269 on the receptor-mediated behavioral responses of rats (333) 123 Westenberg, H.G.M., see Bosker, FJ. (333) 147 Takeuchi, Y., see Ishizaki, K. (333) 207 Wolff, M.C. and Leander, J.D. Tanaka, T., see Matsushima, S. (333) 93 Differentiation of 5-HT,, receptor ligands by drug discrimination Thirstrup, S., Dahl, R. and Nielsen-Kudsk, F (333) 113 Interaction between prostaglandins and selective phosphodiesterase inhibitors in isolated guinea-pig trachea in vitro (333) 215 Xiao, C.-Y., see Chen, M. (333) 261 Thorkildsen, C., see Ebert, B. (333) 99 Tramontana, M., see Giuliani, S. (333) 177 Yamawaki, S., see Takao, K. (333) 123 Tsocas, A., see Souli, A. (333) 87 Yokoshiki, H., Katsube, Y.. Sunagawa, M. and Sperelakis, N. Levosimendan, a novel Ca’* sensitizer, activates the glibenclamide- Ugedo, L., see Ruiz-Ortega, J.A. (333) 159 sensitive K* channel in rat arterial myocytes (333) 249 Van Aken, H., see Waurick, R. (333) 181 Zarrindast, M.-R., see Sawynok, J. (333) | co European Journal of Pharmacology 333 (1997) 297-303 Keyword index Actomyosin ATPase activity Anandamide P-4 (1-methyl-4-piperidy! diphenylpropoxyacetate hydrochloride); Anti- Endothelium; EDHF (endothelium-derived hyperpolarizing factor), K* pollakiuric agent; Urinary bladder; Smooth muscle; Calmodulin channel; Cytochrome P-450 inhibitor; Cannabinoid (Randall, M.D. (333) (Matsushima, S. (333) 93) 191) Adenosine A , receptor Angiotensin II Pain; Histamine; 5-HT (S-hydroxytryptamine, serotonin) (Sawynok, J. Enalapril; L-nitro-arginine methyl ester (L-NAME), Nitric oxide (NO), (333) 1) Stroke (Ahmad, S. (333) 39) Adenosine receptor Antibody MK-801 ((+ )-5-methyl-10,1 1-dihydro-SH-dibenzo-(a,d cyclohepten- Muscarinic M, receptor; Peptide; Inotropic effect; Papillary muscle 5,10-imine maleate), Electroencephalogram; (Rat) (Popoli, P. (333) 143) (Skomedal, T. (333) 169) a ,-Adrenoceptor Anticonvulsant action Peptide YY; Intestinal secretion; VIP (vasoactive intestinal peptide), GYKI 52466 (1-(4-aminopheny!)-4-methyl-7,8-methylendioxy-SH-2,3- Intestinal nerve; o@ Receptor; (Rat) (Souli, A. (333) 87) benzo-diazepine), Excitatory amino acid; Motor system; Flumazenil (Kubova, H. (333) 17) a ,,-Adrenoceptor Locus coeruleus; 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)-tetralin), ARC 239 (2-{2-[4-(0-methoxyphen|y- y!lJ)etphiy!p}-e4,r4-adzimietnhy-|- Antidepressant 1,3(2H,4H)-isoquinolinedione); Chlorpromazine (Ruiz-Ortega, J.A. (333) Desipramine; Microtubule-associated protein 2; Microtubule assembly; 159) Phosphorylation (Miyamoto, S. (333) 279) Adrenomedullin Anti-pollakiuric agent Blood pressure; Renovascular hypertension; Renin; Aldosterone; (Rat) P-4 (\-methyl-4-piperidy! diphenylpropoxyacetate hydrochloride), Uri- (Khan, A.1. (333) 187) nary bladder; Smooth muscle; Actomyosin ATPase activity; Calmodulin (Matsushima, S. (333) 93) Airway PF-904; Airway, hyperreactivity; Eosinophil infiltration; Microvascular Apamin leakage; Bronchus, human, isolated; Phosphodiesterase activity; Neu- Smooth muscle; K* channels; Ca?* stores; Charybdotoxin; Pacemaker trophils, human; Superoxide anion generation; (Guinea pig) (Cortijo, J. cells (Duridanova, D.B. (333) 105) (333) 69) ARC 239 (2-[2-[4-(0-methoxypheny!)piperazin-1-yllethy!]-4,4-di- Airway, hyperreactivity methyl- 13 (2H,4H)-isoquinolinedione) PF-904; Airway; Eosinophil infiltration; Microvascular leakage; Bronchus, Locus coeruleus; a,,-Adrenoceptor,; 8-OH-DPAT (8-hydroxy-2-(di-n- human, isolated; Phosphodiesterase activity; Neutrophils, human; Super- propylamino)-tetralin), Chlorpromazine (Ruiz-Ortega, J.A. (333) 159) oxide anion generation; (Guinea pig) (Cortijo, J. (333) 69) Arrhythmia Airway tone, spontaneous Ischaemia; K* channel activator; Levcromakalim; Reperfusion (Vegh, A. Smooth muscle, airway; Phosphodiesterase inhibitor, Prostaglandin; (333) 33) (Guinea pig) (Thirstrup, S. (333) 215) Aldosterone Aryldiazonium salt Muscarinic receptor; Muscarinic receptor, m2 subtype; Sf9 cells; Cova- Adrenomedullin; Blood pressure; Renovascular hypertension; Renin; (Rat) lent labelling (Weill, C. (333) 269) (Khan, A.1. (333) 187) Alzheimer’s disease Ascomycin Muscarinic M, receptor; Muscarinic M, receptor, Scopolamine; Piren- FK506-binding protein; Neurotransmitter release; Smooth muscle con- zepine; Methoctramine; (Delay-dependent and -independent); (% correct traction; Tachykininergic nerve; Iris sphincter muscle, rabbit (Kageyama, choice) (Aura, J. (333) 129) M. (333) 223) Amygdala, central nucleus of ATP Muscarinic M, receptor; Carbachol; Blood pressure; (Rat) (Aslan, N. Diadenosine pentaphosphate; Diinosine pentaphosphate (Hoyle, C.H.V. (333) 63) (333) RI) 298 Keyword index Auricular artery Ca** overload Sympathetic nerve stimulation; Purinergic transmission; P, , purinoceptor Cardiomyocyte; Lysophosphatidylcholine; Ca** channel blocker; Crea- (Haniuda, K. (333) 163) tine kinase (Chen, M. (333) 261) Bile duct ligation Ca** stores Sodium tauroursodeoxycholate (UR-906); Dehydrocholic acid; Blood co- Smooth muscle; K* channels; Charybdotoxin; Apamin; Pacemaker cells agulation factor; Cholestasis; (Rat) (Ishizaki, K. (333) 207) (Duridanova, D.B. (333) 105) B, knockout mice Calmodulin Vasodilation; Vasoconstriction; Bradykinin; Bradykinin receptor; Mesen- P-4 (1-methyl-4-piperidy! diphenylpropoxyacetate hydrochloride); Anti- teric bed (Berthiaume, N. (333) 55) pollakiuric agent; Urinary bladder; Smooth muscle; Actomyosin ATPase activity (Matsushima, S. (333) 93) Blood coagulation factor Bile duct ligation; Sodium tauroursodeoxycholate (UR-906); Dehydro- Cannabinoid cholic acid; Cholestasis; (Rat) (Ishizaki, K. (333) 207) Endothelium; EDHF (endothelium-derived hyperpolarizing factor); Anan- damide; K* channel; Cytochrome P-450 inhibitor (Randall, M.D. (333) Blood pressure Adrenomedullin; Renovascular hypertension; Renin; Aldosterone; (Rat) 191) (Khan, A.I. (333) 187) Capsaicin Muscarinic M, receptor; Carbachol; Amygdala, central nucleus of; (Rat) Mustard oil; Neurogenic inflammation; Plasma extravasation; Ear oedema; (Aslan, N. (333) 63) SR 140333 (Inoue, H. (333) 231) Nociceptin; Hypotension; Heart rate; Vagal bradycardia (Giuliani, S. Carbachol (333) 177) Muscarinic M, receptor; Blood pressure; Amygdala, central nucleus of; (Rat) (Aslan, N. (333) 63) Opioid; Cocaine; Lethality; Cardiovascular; Seizure (Patterson, A.B. (333) 47) Cardiomyocyte Lysophosphatidylcholine; Ca?* overload; Ca’* channel blocker; Crea- Body temperature tine kinase (Chen, M. (333) 261) Corticosterone; 5-HT,, receptor; 5-HT, receptor; 5-HT (5-hydroxy- tryptamine, serotonin) syndrome; Wet-dog shake (Takao, K. (333) 123) Cardiovascular Bradykinin Opioid; Cocaine; Lethality; Blood pressure; Seizure (Patterson, A.B. (333) 47) Bradykinin receptor antagonist; FR167344; FR172357; Bradykinin B, receptor; Orally active (Inamura, N. (333) 79) CGP 56999A GABA, receptors; Epilepsy (rat); brain slices (Badran, S. (333) 135) Vasodilation; Vasoconstriction; Bradykinin receptor; Mesenteric bed; B, knockout mice (Berthiaume, N. (333) 55) Charybdotoxin Bradykinin B, receptor Smooth muscle; K* channels; Ca** stores; Apamin; Pacemaker cells Bradykinin; Bradykinin receptor antagonist; FR 167344; FR172357; Orally (Duridanova, D.B. (333) 105) active (Inamura, N. (333) 79) Chlorpromazine Bradykinin receptor Locus coeruleus; a,,-Adrenoceptor, 8-OH-DPAT (8-hydroxy-2-(di-n- Vasodilation; Vasoconstriction; Bradykinin; Mesenteric bed; B, knockout propylamino)-tetralin); ARC 239 (2-(2-[4-(o-methoxyphenyl)piperazin-| - mice (Berthiaume, N. (333) 55) ylJethy!]}-14, 3,(24H,-4Hd)-iisomqueintolhinyedlio-ne ) (Ruiz-Ortega, J.A. (333) 159) Bradykinin receptor antagonist Bradykinin; FR167344; FR172357; Bradykinin B, receptor; Orally active Cholestasis (Inamura, N. (333) 79) Bile duct ligation; Sodium tauroursodeoxycholate (UR-906); Dehydro- cholic acid; Blood coagulation factor; (Rat) (Ishizaki, K. (333) 207) Brain slices GABA, receptors; CGP 56999A; Epilepsy (rat) (Badran, S. (333) 135) Cocaine Bronchus, human, isolated Opioid; Lethality; Cardiovascular; Blood pressure; Seizure (Patterson, A.B. (333) 47) PF-904; Airway; Airway, hyperreactivity; Eosinophil infiltration; Mi- crovascular leakage; Phosphodiesterase activity; Neutrophils, human; Su- Cortex, rat peroxide anion generation; (Guinea pig) (Cortijo, J. (333) 69) NMDA receptor antagonist, non-competitive; Electrophysiology; Spinal BU-224 (2-(4,5-dihydroimidazol-2yl)-quinoline hydrochloride)) cord, rat; Enantiomer (Ebert, B. (333) 99) as Imidazoline receptor; Nociception; Spinal cord; (Rat) (Diaz, A. (333) 9) Corticosterone Ca?* channel 5-HT,, receptor; 5-HT, receptor; Body temperature; 5-HT (5-hydroxy- Mn?*; Ileum; Smooth muscle (Nasu, T. (333) 199) tryptamine, serotonin) syndrome; Wet-dog shake (Takao, K. (333) 123) Ca** channel blocker Covalent labelling Cardiomyocyte; Lysophosphatidylcholine; Ca** overload; Creatine ki- Muscarinic receptor; Muscarinic receptor, m2 subtype; Sf9 cells; Aryldia- nase (Chen, M. (333) 261) zonium salt (Weill, C. (333) 269) Keyword index Creatine kinase Eosinophil infiltration Cardiomyocyte; Lysophosphatidylcholine; Ca** overload; Ca** channel PF-904; Airway; Airway, hyperreactivity; Microvascular leakage: blocker (Chen, M. (333) 261) Bronchus, human, isolated; Phosphodiesterase activity; Neutrophils, hu- man; Superoxide anion generation; (Guinea pig) (Cortijo, J. (333) 69) Cytochrome P-450 inhibitor Endothelium; EDHF (endothelium-derived hyperpolarizing factor), Anan- Epilepsy (rat) damide; K* channel; Cannabinoid (Randall, M.D. (333) 191) GABA, receptors; CGP 56999A; brain slices (Badran, S$. (333) 135) Dehydrocholic acid Excitaatmionor ayci d Bile duct ligation; Sodium tauroursodeox ycholate (UR-906), Blood coag- GYKI 52466 (1-44-aminophenyl)-4-methy!-7,8-methylendioxy-SH-2,3- ulation factor; Cholestasis; (Rat) (Ishizaki, K. (333) 207) benzo-diazepine); Anticonvulsant action; Motor system; Flumazenil (Kubova, H. (333) 17) Desipramine Antidepressant; Microtubule-associated protein 2; Microtubule assembly; Feedback regulation Phosphorylation (Miyamoto, S. (333) 279) Flesinoxan; WAY 100635; 5-HT (S-hydroxytryptamine, serotonin), 5- HT,, receptor; Microdialysis; (Rat) (Bosker, FJ. (333) 147) Diadenosine pentaphosphate Diinosine pentaphosphate; ATP (Hoyle, C.H.V. (333) R1) D-Fenfluramine 5-HT (5-hydroxytryptamine, serotonin), D-Norfenfluramine; Sex differ- Diinosine pentaphosphate ence (Datla, K.P. (333) 27) Diadenosine pentaphosphate; ATP (Hoyle, C.H.V. (333) RI) FK506-binding protein Dopexamine Endotoxaemia; Hyperdynamic circulation; Nitric oxide (NO) synthase Ascomycin, Neurotransmitter release; Smooth muscle contraction; inhibition (Waurick, R. (333) 181) Tachykininergic nerve; Iris sphincter muscle, rabbit (Kageyama, M. (333) 223) Drug discrimination 5-HT,, receptor; Efficacy; (Pigeon) (Wolff, M.C. (333) 113) Flesinoxan WAY 100635; 5-HT (5-hydroxytryptamine, serotonin); 5-HT,, receptor; Ear oedema Feedback regulation; Microdialysis; (Rat) (Bosker, FJ. (333) 147) Mustard oil; Neurogenic inflammation; Plasma extravasation; Capsaicin; SR 140333 (Inoue, H. (333) 231) Flumazenil GYKI 52466 (1-(4-aminopheny!)-4-methyl-7,8-methylendioxy-SH-2,3- EDHF (endothelium-derived hyperpolarizing factor) benzo-diazepine), Excitatory amino acid; Anticonvulsant action; Motor Endothelium; Anandamide; K* channel; Cytochrome P-450 inhibitor; system (Kubova, H. (333) 17) Cannabinoid (Randall, M.D. (333) 191) FR167344 Efficacy Bradykinin; Bradykinin receptor antagonist; FR172357; Bradykinin B, 5-HT,, receptor; Drug discrimination; (Pigeon) (Wolff, M.C. (333) 113) receptor, Orally active (Inamura, N. (333) 79) Electroencephalogram FR172357 Adenosine receptor; MK-801 ((+ )-5-methyl-10,1 1-dihydro-SH-dibenzo- Bradykinin; Bradykinin receptor antagonist; FR167344; Bradykinin B, (a,d)cyclohepten-5,10-imine maleate); (Rat) (Popoli, P. (333) 143) receptor; Orally active (Inamura, N. (333) 79) GABA, receptors NMDA receptor antagonist, non-competitive; Cortex, rat; Spinal cord, rat; CGP 56999A; Epilepsy (rat); brain slices (Badran, S. (333) 135) Enantiomer (Ebert, B. (333) 99) y-Glutamyicysteinyletehsytle r Enalapril Glutathione, reduced; Hepatocyte; Glycine; Tert-butyl hydroperoxide Angiotensin Il; L-nitro-arginine methyl ester (L-NAME), Nitric oxide (Nishida, K. (333) 289) (NO), Stroke (Ahmad, S. (333) 39) Glutathione, reduced Enantiomer y-glutamylcysteinylethyl ester; Hepatocyte; Glycine; Tert-buty! hydroper- NMDA receptor antagonist, non-competitive; Electrophysiology; Cortex, oxide (Nishida, K. (333) 289) rat; Spinal cord, rat (Ebert, B. (333) 99) Endothelium Glycine EDHF (endothelium-derived hyperpolarizing factor), Anandamide; K* y-glutamylcysteinylethy! ester; Glutathione, reduced; Hepatocyte; Tert- channel; Cytochrome P-450 inhibitor; Cannabinoid (Randall, M.D. (333) butyl hydroperoxide (Nishida, K. (333) 289) 191) GYKI 52466 (1-(4-aminophenyl)-4-methy!-7,8-methylendioxy-SH- Endotoxaemia 2,3-benzo-diazepine) Hyperdynamic circulation; Nitric oxide (NO) synthase inhibition, Dopex- Excitatory amino acid; Anticonvulsant action; Motor system; Flumazenil amine (Waurick, R. (333) 181) (Kubova, H. (333) 17) Endotoxin Heart rate Neostigmine; Neurotransmission; Na*, K *-ATPase; N°-nitro-L-arginine Nociceptin; Blood pressure; Hypotension; Vagal bradycardia (Giuliani, S. (Liu, S.-H. (333) 241) (333) 177) 300 Keyword index Hepatocyte Ischaemia y-glutamylcysteinylethyl ester; Glutathione, reduced; Glycine; Tert-buty! Arrhythmia; K* channel activator, Levcromakalim; Reperfusion (Vegh, hydroperoxide (Nishida, K. (333) 289) A. (333) 33) Histamine K * channel Adenosine A, receptor; Pain; 5-HT (S-hydroxytryptamine, serotonin) Endothelium; EDHF (endothelium-derived hyperpolarizing factor), Anan- (Sawynok, J. (333) 1) damide; Cytochrome P-450 inhibitor; Cannabinoid (Randall, M.D. (333) 191) 5-HT (5-hydroxytryptamine, serotonin) syndrome Corticosterone; 5-HT,, receptor; 5-HT, receptor; Body temperature; Levosimendan; K* channel, ATP-sensitive; Patch clamp technique; Wet-dog shake (Takao, K. (333) 123) Mesenteric artery, rat (Yokoshiki, H. (333) 249) 5-HT (5-hydroxytryptamine, serotonin) K * channel activator p-Fenfluramine; D-Norfenfluramine; Sex difference (Datla, K.P. (333) 27) Arrhythmia; Ischaemia; Levcromakalim; Reperfusion (Vegh, A. (333) 33) Adenosine A, receptor; Pain; Histamine (Sawynok, J. (333) 1) K * channel, ATP-sensitive Levosimendan; K* channel; Patch clamp technique; Mesenteric artery, Flesinoxan; WAY 100635; 5-HT,, receptor; Feedback regulation; Micro- rat (Yokoshiki, H. (333) 249) dialysis; (Rat) (Bosker, F.J. (333) 147) K * channels 5-HT,, receptor Smooth muscle; Ca** stores; Charybdotoxin; Apamin; Pacemaker cells Corticosterone; 5-HT, receptor; Body temperature; 5-HT (5-hydroxy- (Duridanova, D.B. (333) 105) tryptamine, serotonin) syndrome; Wet-dog shake (Takao, K. (333) 123) Lethality Efficacy; Drug discrimination; (Pigeon) (Wolff, M.C. (333) 113) Opioid; Cocaine; Cardiovascular; Blood pressure; Seizure (Patterson, A.B. (333) 47) Flesinoxan; WAY 100635; 5-HT (S-hydroxytryptamine, serotonin); Feed- back regulation; Microdialysis; (Rat) (Bosker, FJ. (333) 147) Levcromakalim Arrhythmia; Ischaemia; K* channel activator; Reperfusion (Vegh, A. 5-HT, receptor (333) 33) Corticosterone; 5-HT,, receptor; Body temperature; 5-HT (5-hydroxy- tryptamine, serotonin) syndrome; Wet-dog shake (Takao, K. (333) 123) Levosimendan K* channel; K* channel, ATP-sensitive; Patch clamp technique; Mesen- Hyperdynamic circulation teric artery, rat (Yokoshiki, H. (333) 249) Endotoxaemia; Nitric oxide (NO) synthase inhibition; Dopexamine (Waurick, R. (333) 181) Locus coeruleus a@,,-Adrenoceptor; 8-OH-DPAT (8-hydroxy-2-di-n-propylamino)-tetra- Hypotension lin); ARC 239 (2-[2-[4-(0-methoxypheny!)|p- yilJpetehry!a}-z4i,4n-d-i- Nociceptin; Blood pressure; Heart rate; Vagal bradycardia (Giuliani, S. (333) 177) methyl-!,3(2H,4H)-isoquinolinedione), Chlorpromazine (Ruiz-Ortega, J.A. (333) 159) lleum Mn?*; Smooth muscle; Ca?* channel (Nasu, T. (333) 199) Lysophosphatidyicholine Cardiomyocyte; Ca** overload; Ca** channel blocker; Creatine kinase Neuropeptide Y; Neuropeptide Y Y,; receptor; (Rabbit) (Pheng, L.H. (Chen, M. (333) 261) (333) R3) Mesenteric artery, rat Imidazoline receptor Levosimendan; K* channel; K* channel, ATP-sensitive; Patch clamp BU-224 (2-(4,5-dihydroimidazol-2yl)-quinoline hydrochloride)); Nocicep- technique (Yokoshiki, H. (333) 249) tion; Spinal cord; (Rat) (Diaz, A. (333) 9) Mesenteric bed — Inotropic effect Vasodilation; Vasoconstriction; Bradykinin; Bradykinin receptor; B, Muscarinic M, receptor; Antibody; Peptide; Papillary muscle (Skomedal, knockout mice (Berthiaume, N. (333) 55) T. (333) 169) Methoctramine Intestinal nerve Muscarinic M, receptor; Muscarinic M, receptor; Scopolamine; Piren- Peptide YY; Intestinal secretion; VIP (vasoactive intestinal peptide), zepine, Alzheimer’s disease; (Delay-dependent and -independent), (% a,-Adrenoceptor, @ Receptor; (Rat) (Souli, A. (333) 87) correct choice) (Aura, J. (333) 129) Intestinal secretion M Peptide YY; VIP (vasoactive intestinal peptide); Intestinal nerve; a,- Flesinoxan; WAY 100635; 5-HT (S-hydroxytryptamine, serotonin); 5- Adrenoceptor; a Receptor; (Rat) (Souli, A. (333) 87) HT,, receptor; Feedback regulation; (Rat) (Bosker, FJ. (333) 147) Iris sphincter muscle, rabbit Microtubule assembly Ascomycin; FK506-binding protein; Neurotransmitter release; Smooth Antidepressant; Desipramine; Microtubule-associated protein 2; Phospho- muscle contraction; Tachykininergic nerve (Kageyama, M. (333) 223) rylation (Miyamoto, S. (333) 279) Keyword index Microtubule-associated protein 2 Neuropeptide Y Y, receptor Antidepressant; Desipramine; Microtubule assembly; Phosphorylation lleum; Neuropeptide Y; (Rabbit) (Pheng, L.H. (333) R3) (Miyamoto, S. (333) 279) Microvascular leakage Endotoxin; Neostigmine; Na*, K*-ATPase; N°-nitro-t-arginine (Liu, PF-904, Airway; Airway, hyperreactivity; Eosinophil infiltration; S.-H. (333) 241) Bronchus, human, isolated; Phosphodiesterase activity; Neutrophils, hu- man; Superoxide anion generation; (Guinea pig) (Cortijo, J. (333) 69) Neurotransmitter release Ascomycin,; FK506-binding protein; Smooth muscle contraction; MK-801 (( + )-5-methyl-10,11-dihydro-SH-dibenzo-(a,d)cyclohepten- Tachykininergic nerve; Iris sphincter muscle, rabbit (Kageyama, M. (333) 5,10-imine maleate) 223) Adenosine receptor; Electroencephalogram; (Rat) (Popoli, P. (333) 143) Neutrophils, human Mn’* PF-904, Airway; Airway, hyperreactivity; Eosinophil infiltration; Mi- Ileum; Smooth muscle; Ca** channel (Nasu, T. (333) 199) crovascular leakage; Bronchus, human, isolated; Phosphodiesterase activ- ity; Superoxide anion generation; (Guinea pig) (Cortijo, J. (333) 69) Motor system GYKI 52466 (1-(4-aminopheny!)-4-methyl-7,8-methylendioxy-5H-2,3- Nitric oxide (NO) benzo-diazepine); Excitatory amino acid; Anticonvulsant action; Angiotensin II; Enalapril; L-nitro-arginine methy! ester (L-NAME), Stroke Flumazenil (Kubova, H. (333) 17) (Ahmad, S. (333) 39) Muscarinic M, receptor Nitric oxide (NO) synthase inhibition Carbachol; Blood pressure; Amygdala, central nucleus of; (Rat) (Aslan, Endotoxaemia; Hyperdynamic circulation; Dopexamine (Waurick, R. N. (333) 63) (333) 181) Muscarinic M, receptor, Scopolamine; Pirenzepine, Methoctramine; N°-Nitro-t-arginine Alzheimer's disease; (Delay-dependent and -independent), (% correct Endotoxin; Neostigmine; Neurotransmission; Na*, K*-ATPase (Liu, S.- choice) (Aura, J. (333) 129) H. (333) 241) Muscarinic M, receptor NMDA receptor antagonist, non-competitive Antibody; Peptide; Inotropic effect; Papillary muscle (Skomedal, T. (333) Electrophysiology; Cortex, rat; Spinal cord, rat; Enantiomer (Ebert, B. 169) (333) 99) Muscarinic M, receptor, Scopolamine; Pirenzepine; Methoctramine; Nociceptin Alzheimer’s disease; (Delay-dependent and -independent); (% correct choice) (Aura, J. (333) 129) Blood pressure; Hypotension; Heart rate; Vagal bradycardia (Giuliani, S. (333) 177) Muscarinic receptor Muscarinic receptor, m2 subtype; Sf9 cells; Covalent labelling; Aryldia- Nociception zonium salt (Weill, C. (333) 269) Imidazoline receptor, BU-224 (244,5-dihydroimidazol-2yl)-quinoline hy- drochloride)), Spinal cord; (Rat) (Diaz, A. (333) 9) Muscarinic receptor, m2 subtype D-Norfenfluramine Muscarinic receptor; Sf9 cells; Covalent labelling; Aryldiazonium salt (Weill, C. (333) 269) D-Fenfluramine; 5-HT (5-hydroxytryptamine, serotonin), Sex difference (Datla, K.P. (333) 27) Mustard oil 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)-tetralin) Neurogenic inflammation; Plasma extravasation; Ear oedema; Capsaicin; SR 140333 (Inoue, H. (333) 231) Locus coeruleus; a@,,-Adrenoceptor, ARC 239 (2-(2-(4-0-metho- xypheny| )piperazin- | -ylJethyl}-4,4-di|m ethyl- 3(2H,4H)-isoquinolinedione ), Na*, K *-ATPase Chlorpromazine (Ruiz-Ortega, J.A. (333) 159) Endotoxin; Neostigmine; Neurotransmission; N°-nitro-L-arginine (Liu, S.-H. (333) 241) Opioid Cocaine; Lethality; Cardiovascular; Blood pressure; Seizure (Patterson, L-Nitro-arginine methyl ester (L-NAME) A.B. (333) 47) Angiotensin II, Enalapril; Nitric oxide (NO), Stroke (Ahmad, S. (333) 39) Orally active Neostigmine Bradykinin; Bradykinin receptor antagonist; FR167344; FR172357; Endotoxin; Neurotransmission; Na*, K*-ATPase; N“°-nitro-t-arginine Bradykinin B, receptor (Inamura, N. (333) 79) (Liu, S.-H. (333) 241) Pacemaker cells Smooth muscle; K* channels; Ca** stores; Charybdotoxin; Apamin Neurogenic inflammation Mustard oil; Plasma extravasation; Ear oedema; Capsaicin; SR 140333 (Duridanova, D.B. (333) 105) (Inoue, H. (333) 231) Pain Neuropeptide Y Adenosine A, receptor; Histamine; 5-HT (5-hydroxytryp lleum; Neuropeptide Y Y, receptor; (Rabbit) (Pheng, L.H. (333) R3) tonin) (Sawynok, J. (333) 1) Keyword index Papillary muscle Renovascular hypertension Muscarinic M, receptor; Antibody; Peptide; Inotropic effect (Skomedal, Adrenomedullin; Blood pressure; Renin; Aldosterone; (Rat) (Khan, A.1. T. (333) 169) (333) 187) Patch clamp technique Reperfusion Levosimendan; K* channel; K* channel, ATP-sensitive; Mesenteric Arrhythmia; Ischaemia; K* channel activator; Levcromakalim (Vegh, A. artery, rat (Yokoshiki, H. (333) 249) (333) 33) Peptide Scopolamine Muscarinic M, receptor; Antibody; Inotropic effect; Papillary muscle Muscarinic M, receptor; Muscarinic M, receptor; Pirenzepine; Methoc- (Skomedal, T. (333) 169) tramine; Alzheimer’s disease; (Delay-dependent and -independent), (% correct choice) (Aura, J. (333) 129) Peptide YY Intestinal secretion; VIP (vasoactive intestinal peptide); Intestinal nerve; Seizure a,-Adrenoceptor; a Receptor; (Rat) (Souli, A. (333) 87) Opioid; Cocaine; Lethality; Cardiovascular; Blood pressure (Patterson, A.B. (333) 47) PF-904 Sex difference Airway; Airway, hyperreactivity; Eosinophil infiltration; Microvascular leakage; Bronchus, human, isolated; Phosphodiesterase activity; Neu- D-Fenfluramine, 5-HT (S-hydroxytryptamine, serotonin); D-Norfenflura- trophils, human; Superoxide anion generation; (Guinea pig) (Cortijo, J. mine (Datla, K.P. (333) 27) (333) 69) Sf9 cells Phosphodiesterase activity Muscarinic receptor; Muscarinic receptor, m2 subtype; Covalent la- PF-904; Airway; Airway, hyperreactivity; Eosinophil infiltration; Mi- belling; Aryldiazonium salt (Weill, C. (333) 269) crovascular leakage; Bronchus, human, isolated; Neutrophils, human; Smooth muscle Superoxide anion generation; (Guinea pig) (Cortijo, J. (333) 69) K* channels; Ca** stores; Charybdotoxin; Apamin; Pacemaker cells (Duridanova, D.B. (333) 105) Phosphodiesterase inhibitor Smooth muscle, airway; Airway tone, spontaneous; Prostaglandin; Mn?*; Ieum; Ca?* channel (Nasu, T. (333) 199) (Guinea pig) (Thirstrup, S. (333) 215) P-4 (1-methyl-4-piperidyl diphenylpropoxyacetate hydrochloride); Anti- Phosphorylation pollakiuric agent; Urinary bladder; Actomyosin ATPase activity; Calmod- Antidepressant; Desipramine; Microtubule-associated protein 2; Micro- ulin (Matsushima, S. (333) 93) tubule assembly (Miyamoto, S. (333) 279) Smooth muscle, airway Pirenzepine Airway tone, spontaneous; Phosphodiesterase inhibitor; Prostaglandin; Muscarinic M, receptor; Muscarinic M, receptor; Scopolamine; Methoc- (Guinea pig) (Thirstrup, S. (333) 215) tramine; Alzheimer’s disease; (Delay-dependent and -independent); (% correct choice) (Aura, J. (333) 129) Smooth muscle contraction Ascomycin; FK506-binding protein; Neurotransmitter release; Plasma extravasation Tachykininergic nerve; Iris sphincter muscle, rabbit (Kageyama, M. (333) Mustard oil; Neurogenic inflammation; Ear oedema; Capsaicin; SR 223) 140333 (Inoue, H. (333) 231) Sedium tauroursodeoxycho(UlRa-9t0e6 ) P-4 (1-methyl-4-piperidyl diphenylpropoxyacetate hydrochloride) Bile duct ligation; Dehydrocholic acid; Blood coagulation factor; Anti-pollakiuric agent; Urinary bladder; Smooth muscle; Actomyosin Cholestasis; (Rat) (Ishizaki, K. (333) 207) ATPase activity; Calmodulin (Matsushima, S. (333) 93) Spinal cord P,, purinoceptor Imidazoline receptor, BU-224 (2-(4,5-dihydroimidazol-2y!)-quinoline hy- Auricular artery; Sympathetic nerve stimulation; Purinergic transmission drochloride)); Nociception; (Rat) (Diaz, A. (333) 9) (Haniuda, K. (333) 163) Spinal cord, rat Prostaglandin NMDA receptor antagonist, non-competitive; Electrophysiology; Cortex, Smooth muscle, airway; Airway tone, spontaneous; Phosphodiesterase rat; Enantiomer (Ebert, B. (333) 99) inhibitor; (Guinea pig) (Thirstrup, S. (333) 215) SR 140333 Purinergic transmission Mustard oil; Neurogenic inflammation; Plasma extravasation, Ear oedema; Auricular artery; Sympathetic nerve stimulation; P,, purinoceptor Capsaicin (Inoue, H. (333) 231) (Haniuda, K. (333) 163) Stroke o Receptor Angiotensin II; Enalapril; L-nitro-arginine methy! ester (L-NAME), Nitric Peptide YY; Intestinal secretion; VIP (vasoactive intestinal peptide); oxide (NO) (Ahmad, S. (333) 39) Intestinal nerve; a-Adrenoceptor; (Rat) (Souli, A. (333) 87) Superoxide anion generation Renin PF-904; Airway; Airway, hyperreactivity; Eosinophil infiltration; Mi- Adrenomedullin; Blood pressure; Renovascular hypertension; Aldos- crovascular leakage; Bronchus, human, isolated; Phosphodiesterase activ- terone; (Rat) (Khan, A.I. (333) 187) ity; Neutrophils, human; (Guinea pig) (Cortijo, J. (333) 69)

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