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European Journal of Pharmacology 1992: Vol 218 Index PDF

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European Journal of Pharmacology, 218 (1992) 379-382 © 1992 Elsevier Science Publishers B.V. All rights reserved 0014-2999 /92 /$05.00 Author index Abe, Y., see Nishiyama, A. (218) 311 Caricati-Neto, A., Sette, M. and Jurkiewicz, A. Abraham, S.T. and Rice, PJ. Increased density of a-adrenoceptors in vas deferens of sponta- Protein kinase C-mediated contractile response of the rat vas neously hypertensive rats (SHR), indicated by functional and deferens (218) 243 receptor binding studies (218) 51 Aceves, J., see Montafio, J.-A.A. (218) 335 Case, C.L., Ravin, R.R., Holani, R., Gillette, P.C. and Hewett, K.W. Ackerman, J.M. and White, F.J. The developmental electrophysiologic effects of moricizine HCI Decreased activity of rat Al0 dopamine neurons following with- on the canine cardiac purkinje fiber (218) 213 drawal from repeated cocaine (218) 171 Chamienia, A.L. and Johns, E_J. Aikawa, T., see Itabashi, S. (218) 187 The influence of changes in perfusion pressure and angiotensin II Aki, Y., see Nishiyama, A. (218) 311 on the renal excretory responses to atrial natriuretic peptides Alesiani, M., see Moroni, F. (218) 145 (218) 319 Andre, P., Ferrat, T., Steinman, M. and Olpe, H.-R. Cheng, C.H.K., see Barnes, N.M. (218) 91 Increased acetylcholine and quisqualate responsiveness after Chiba, S., see Iwatsuki, K. (218) 237 blockade of GABA, receptors (218) 137 Choiniere, D., see Wrathall, J.R. (218) 273 Andrews, N., see File, $.£. (218) 9 Ciuffi, M., see Moroni, F. (218) 145 Arhem, P., see Veintemilla, F. (218) 59 Cohen, M.L., see Killam, A.L. (218) 295 Arnt, J., Lembol, H.L., Meier, E. and Pedersen, H. Connell, T.A., see Zhou, L.-W. (218) 219 Discriminative stimulus properties of the muscarinic receptor Conroy, D.M., Samhoun, M.M. and Piper, P_J. agonists Lu 26-046 and O-Me-THPO in rats: evidence for in- Vasoactive intestinal peptide and helodermin inhibit the release volvement of different muscarinic receptor subtypes (218) 159 of cyclo-oxygenase products induced by leukotriene D, and bradykinin from guinea-pig perfused lung (218) 43 Barnes, N.M., Cheng, C.H.K., Costall, B., Ge, J., Kelly, M.E. and Costall, B., see Barnes, N.M. (218) 15 Naylor, RJ. Costall, B., see Barnes, N.M. (218) 91 Profiles of interaction of R(+)/S(—)-zacopride and anxiolytic agents in a mouse model (218) 91 Debaert, M., see Ong, J. (218) 343 Barnes, N.M., Costall, B., Ge, J., Kelly, M.E. and Naylor, R.J. De Witte, P., see Nijs, G. (218) 199 The interaction of R(+)- and S(—)-zacopride with PCPA to modify rodent aversive behaviour (218) 15 Elinder, F., see Veintemilla, F. (218) 59 Barrachina, M.D., see Martinez-Cuesta, M.A. (218) 351 Endoh, M., Takanashi, M. and Norota, I. Basilico, L., Parolaro, D., Rubino, T., Gori, E. and Giagnoni, G. Effects of vasopressin on phosphoinositide hydrolysis and my- Influence of w-conotoxin on morphine analgesia and withdrawal ocardial contractility (218) 355 syndrome in rats (218) 75 Engels, F., see Buckley, T.L. (218) 369 Beil, W., Staar, U. and Sewing, K.-Fr. Entzeroth, M., see Zhang, J. (218) 35 Pantoprazole: a novel H*/K*-ATPase inhibitor with an im- Eriksson, E., see Nilsson, C. (218) 205 proved pH stability (218) 265 Esplugues, J.V., see Martinez-Cuesta, M.A. (218) 351 Beinborn, M., see Hennies, S. (218) 303 Berthelot, P., see Ong, J. (218) 343 Facci, L., see Moroni, F. (218) 145 Bill, D.J., Fletcher, A., Glenn, B.D. and Knight, M. Fadda, E., see Moroni, F. (218) 145 Behavioural studies on WAY100289, a novel 5-HT, receptor Ferrat, T., see Andre, P. (218) 137 antagonist, in two animal models of anxiety (218) 327 File, S.E., Andrews, N., Wu, P.Y., Zharkovsky, A. and Zangrossi, Jr., Boja, J.W., see Rosténe, W. (218) 175 H. Bond, A. and Boot, J.R. Modification of chlordiazepoxide’s behavioural and neurochemi- The effect of calcium channel modulators on blood pressure and cal effects by handling and plus-maze experience (218) 9 pressor responses to noradrenaline in the guinea-pig (218) 179 Fletcher, A., see Bill, D.J. (218) 327 Boot, J.R., see Bond, A. (218) 179 Flouquet, N., see Ong, J. (218) 343 Bouzoukis, J., see Wrathall, J.R. (218) 273 Fukushima, Y., see Kawabata, A. (218) 153 Broccardo, M. and Improta, G. Fukuzumi, Y., see Kawabata, A. (218) 153 Antidiarrheal and colonic antipropulsive effects of spinal and supraspinal administration of the natural 6 opioid receptor ago- Galli, A., see Moroni, F. (218) 145 nist, [D-Ala? ]deltorphin II, in the rat (218) 69 Ge, J., see Barnes, N.M. (218) 15 Buckley, T.L., Van de Velde, M.J., Henricks, P:A.J., Engels, F. and Ge, J., see Barnes, N.M. (218) 91 Nijkamp, F.P. Geboes, K., see Nijs, G. (218) 199 13-Hydroxyoctadecadienoic acid attenuates oedema formation Giagnoni, G., see Basilico, L. (218) 75 induced by leukotriene B, in vivo in rabbit skin (218) 369 Giao-T. Rico, J.M., see Macara, B. (218) 27 Bunker, C.F., see Hanson, G.R. (218) 287 Gibb, J.W., see Hanson, G.R. (218) 287 Bush, L., see Hanson, G.R. (218) 287 Gillette, P.C., see Case, C.L. (218) 213 380 Glenn, B.D., see Bill, DJ. (218) 327 Kelly, M.E., see Barnes, N.M. (218) 15 Gommeren, W., see Schotte, A. (218) 373 Kelly, M.E., see Barnes, N.M. (218) 91 Gori, E., see Basilico, L. (218) 75 Kerr, D.1.B., see Ong, J. (218) 343 Gradin, K., Qadri, F., Nomikos, G.G., Hillegaart, V. and Svensson, Killam, A.L. and Cohen, M.L. T.H. Presence of B- but not a-adrenoceptors in the rat jugular vein: Substance P injection into the dorsal raphe increases blood autoradiographical evidence (218) 295 pressure and serotonin release in hippocampus of conscious rats Kindgen-Milles, D. and Klement, W. (218) 363 Pain and inflammation evoked in human skin by bradykinin Gross, R., see Hillaire-Buys, D. (218) 359 receptor antagonists (218) 183 Gundlach, A.L., see King, P.R. (218) 101 King, P.R., Gundlach, A.L., Jarrott, B. and Louis, W.J. a,-Adrenoceptor and catecholamine-insensitive binding sites for Hampson, D.R., Huang, X.-p., Wells, J.W., Walter, J.A. and Wright, {*H]rilmenidine in membranes from rat cerebral cortex (218) 101 J.L.C. Kiyomoto, H., see Nishiyama, A. (218) 311 Interaction of domoic acid and several derivatives with kainic Klement, W., see Kindgen-Milles, D. (218) 183 acid and AMPA binding sites in rat brain (218) 1 Knight, M., see Bill, D.J. (218) 327 Hanson, G.R., Bunker, C.F., Johnson, M., Bush, L. and Gibb, J.W. Ko, F.-N., Wu, T.-S., Liou, M.-J., Huang, T.-F. and Teng, C.-M. Response of monoaminergic and neuropeptide systems to 4- PAF antagonism in vitro and in vivo by aglafoline from Aglaia methylaminorex: a new stimulant of abuse (218) 287 elliptifolia Merr (218) 129 Harsing, Jr., L.G., Sershen, H., Toth, E., Hashim, A., Ramacci, M.T. Kuhar, M.J., see Rosténe, W. (218) 175 and Lajtha, A. Acetyl-L-carnitine releases dopamine in rat corpus striatum: an Lajtha, A., see Harsing, Jr., L.G. (218) 117 in vivo microdialysis study (218) 117 Lee, C.-R., see Huang, H.-C. (218) 123 Hashim, A., see Harsing, Jr., L-G. (218) 117 Lee, M.-C., see Huang, H.-C. (218) 123 He, H., see Nishiyama, A. (218) 311 Lee, Y.-T., see Huang, H.-C. (218) 123 Hennies, S., Beinborn, M. and Sewing, K.-F. Lembgl, H.L., see Arnt, J. (218) 159 Gastric prostaglandin E, receptors are the common antisecretory Lemli, J., see Nijs, G. (218) 199 target of mucosal prostanoids (218) 303 Leysen, J.E., see Schotte, A. (218) 373 Henricks, P.A.J., see Buckley, T.L. (218) 369 Liou, M.-J., see Ko, F.-N. (218) 129 Hewett, K.W., see Case, C.L. (218) 213 Lombardi, G., see Moroni, F. (218) 145 Hillaire-Buys, D., Gross, R., Roye, M., Ribes, G. and Loubatiéres- Lopez-Belmonte, J., see Whittle, B.J.R. (218) 339 Mariani, M.-M. Loubatiéres-Mariani, M.-M., see Hillaire-Buys, D. (218) 359 Adrenergic inhibition of insulin secretion involves pertussis Louis, W.J., see King, P.R. (218) 101 toxin-sensitive and -insensitive mechanisms (218) 359 Luyten, W.H.L.M., see Schotte, A. (218) 373 Hillegaart, V., see Gradin, K. (218) 363 Holani, R., see Case, C.L. (218) 213 Macara, B. and Giao-T. Rico, J.M. Huang, H.-C., Lee, C.-R., Weng, Y.-I., Lee, M.-C. and Lee, Y.-T. Effect of Ca?* modulators on acetylcholine-induced phasic and Vasodilator effect of scoparone (6,7-dimethoxycoumarin) from a tonic contractions and A23187-induced contractions in ileal longi- Chinese herb (218) 123 tudinal muscle and IP, production (218) 27 Huang, T.-F., see Ko, F.-N. (218) 129 Martinez-Cuesta, M.A., Barrachina, M.D., Piqué, J.M., Whittle, Huang, X.-p., see Hampson, D.R. (218) 1 B.J.R. and Esplugues, J.V. The role of nitric oxide and platelet-activating factor in the Improta, G., see Broccardo, M. (218) 69 inhibition by endotoxin of pentagastrin-stimulated gastric acid Inui, J., see Itoh, H. (218) 347 secretion (218) 351 Itabashi, S., Aikawa, T., Sekizawa, K., Sasaki, H. and Takishima, T. Martinez-Fong, D., see Montano, J.-A.A. (218) 335 Evidence that an atypical B-adrenoceptor mediates the prejunc- Masumura, H., see Nishiyama, A. (218) 311 tional inhibition of non-adrenergic non-cholinergic contraction in McDonough, J.R., see Mele, P.C. (218) 229 guinea-pig bronchi (218) 187 McLean, D.B., see Mele, P.C. (218) 229 Itoh, H., Sato, Y., Taniguchi, K., Nakagawa, H., Inui, J. and Takeuchi, Meier, E., see Arnt, J. (218) 159 J. Mele, P.C., McDonough, J.R., McLean, D.B. and O'Halloran, K.P. Differences between vasorelaxant responses of the canine and Cisplatin-induced conditioned taste aversion: attenuation by dex- human mesenteric arteries and veins to amrinone (218) 347 amethasone but not zacopride or GR38032F (218) 229 Ivy Carroll, F., see Rosténe, W. (218) 175 Messing, M.W.J., see Struijker Boudier, H.A.J. (218) 191 Iwao, H., see Nishiyama, A. (218) 311 Mihic, S.J., Van Berckel, B.N.M., O'Dowd, B.F., Nguyen, T. and Iwatsuki, K., Ren, L.-M. and Chiba, S. Wu, P.H. Effects of YM435, a novel dopamine D, receptor agonist, on Effects of sedatives on GABA-mediated chloride flux into cere- pancreatic exocrine secretion in anesthetized dogs (218) 237 bral cortical microsacs prepared from emotional and non-emo- tional mice (218) 283 Janssen, P.F.M., see Schotte, A. (218) 373 Moerlein, $.M. and Perlmutter, J.S. Jarrott, B., see King, P.R. (218) 101 Binding of 5-(2’-['*F]fluoroethyl)flumazenil to central benzodi- Johns, E.J., see Chamienia, A.L. (218) 319 azepine receptors measured in living baboon by positron emission Johnson, M., see Hanson, G.R. (218) 287 tomography (218) 109 Jurkiewicz, A., see Caricati-Neto, A. (218) 51 Moncada, S., see Whittle, B.J.R. (218) 339 Montano, J.-A.A., Martinez-Fong, D. and Aceves, J. Kawabata, A., Fukuzumi, Y., Fukushima, Y. and Takagi, H. GABA , receptor activation partially inhibits N-methyl-D-aspar- Antinociceptive effect of L-arginine on the carrageenin-induced tate-mediated tyrosine hydroxylase stimulation in rat striatal slices hyperalgesia of the rat: possible involvement of central opioider- (218) 335 gic systems (218) 153 Mori, F., see Moroni, F. (218) 145 Moroni, F., Alesiani, M., Facci, L., Fadda, E., Skaper, $.D., Galli, Roye, M., see Hillaire-Buys, D. (218) 359 A., Lombardi, G., Mori, F., Ciuffi, M., Natalini, B. and Pellic- Rubino, T., see Basilico, L. (218) 75 ciari, R. Thiokynurenates prevent excitotoxic neuronal death in vitro and Samhoun, M.M., see Conroy, D.M. (218) 43 in vivo by acting as glycine antagonists and as inhibitors of lipid Sasaki, H., see Itabashi, S. (218) 187 peroxidation (218) 145 Sato, Y., see Itoh, H. (218) 347 Miller, S. and Nigam, S. Satoh, H. and Sperelakis, N. Arachidonic acid release and platelet-activating factor formation Taurine inhibition of fast Na* current in embryonic chick ven- by staurosporine in human neutrophils challenged with n-formyl tricular myocytes (218) 83 peptide (218) 251 Scherman, D., see Rosténe, W. (218) 175 Schotte, A., Janssen, P.F.M., Gommeren, W., Luyten, W.H.L.M. and Nagase, H., see Portoghese, P.S. (218) 195 Leysen, J.E. Nakagawa, H., see Itoh, H. (218) 347 Autoradiographic evidence for the occlusion of rat brain Natalini, B., see Moroni, F. (218) 145 dopamine D, receptors in vivo (218) 373 Naylor, R.J., see Barnes, N.M. (218) 15 Sekizawa, K., see Itabashi, S. (218) 187 Naylor, R.J., see Barnes, N.M. (218) 91 Sershen, H., see Harsing, Jr., L.G. (218) 117 Nguyen, T., see Mihic, S.J. (218) 283 Sette, M., see Caricati-Neto, A. (218) 51 Nigam, S., see Miller, S. (218) 251 Sewing, K.-Fr., see Beil, W. (218) 265 Nijkamp, F.P., see Buckley, T.L. (218) 369 Sewing, K.-F., see Hennies, S. (218) 303 Nijs, G., De Witte, P., Geboes, K. and Lemii, J. Skaper, S.D., see Moroni, F. (218) 145 Influence of rhein anthrone and rhein on small intestine transit Sperelakis, N., see Satoh, H. (218) 83 rate in rats: evidence of prostaglandin mediation (218) 199 Staar, U., see Beil, W. (218) 265 Nilsson, C. and Eriksson, E. Steinman, M., see Andre, P. (218) 137 Partial dopamine D, receptor agonists antagonize prolactin-regu- Struijker Boudier, H.A.J., Messing, M.W.J. and Van Essen, H. lating D, receptors in a transfected clonal cell line (GH,ZR,) Preferential small arteriolar vasodilatation by the potassium (218) 205 channel opener, BRL 38227, in conscious spontaneously hyper- Nishiyama, A., Tamaki, T., Masumura, H., He, H., Kiyomoto, H., tensive rats (218) 191 Aki, Y., Yamamoto, A., Iwao, H. and Abe, Y. Sultana, M., see Portoghese, P.S. (218) 195 Effects of semotiadil fumarate (SD-3211) on renal hemodynamics Svensson, T.H., see Gradin, K. (218) 363 and function in dogs (218) 311 Nomikos, G.G., see Gradin, K. (218) 363 Taira, N., see Okada, Y. (218) 259 Norota, I., see Endoh, M. (218) 355 Takagi, H., see Kawabata, A. (218) 153 Takanashi, M., see Endoh, M. (218) 355 O'Dowd, B.F., see Mihic, S.J. (218) 283 Takemori, A.E., see Portoghese, P.S. (218) 195 O'Halloran, K.P., see Mele, P.C. (218) 229 Takeuchi, J., see Itoh, H. (218) 347 Okada, Y., Yanagisawa, T. and Taira, N. Takishima, T., see Itabashi, S. (218) 187 E4080 has a dual action, as a K* channel opener and a Ca?* Tamaki, T., see Nishiyama, A. (218) 311 channel blocker, in canine coronary artery smooth muscle (218) Taniguchi, K., see Itoh, H. (218) 347 259 Teng, C.-M., see Ko, F.-N. (218) 129 Olpe, H.-R., see Andre, P. (218) 137 Toth, E., see Harsing, Jr., L.G. (218) 117 Ong, J., Kerr, D.1.B., Berthelot, P., Vaccher, C., Flouquet, N. and Trifiletti, R.R. Debaert, M. Neuroprotective effects of N©-nitro-L-arginine in focal stroke in Actions of thienyl analogs of baclofen in the guinea-pig isolated the 7-day old rat (218) 197 ileum (218) 343 Vaccher, C., see Ong, J. (218) 343 Parolaro, D., see Basilico, L. (218) 75 Van Berckel, B.N.M., see Mihic, $.J. (218) 283 Pedersen, H., see Arnt, J. (218) 159 Van de Velde, M.J., see Buckley, T.L. (218) 369 Pellicciari, R., see Moroni, F. (218) 145 Van Essen, H., see Struijker Boudier, H.A.J. (218) 191 Perlmutter, J.S., see Moerlein, $.M. (218) 109 Van Meel, J.C.A., see Zhang, J. (218) 35 Piper, P.J., see Conroy, D.M. (218) 43 Veintemilla, F., Elinder, F. and Arhem, P. Piqué, J.M., see Martinez-Cuesta, M.A. (218) 351 Mechanisms of propofol action on ion currents in the myelinated Portoghese, P.S., Sultana, M., Nagase, H. and Takemori, A.E. axon of Xenopus laevis (218) 59 A highly selective 5,-opioid receptor antagonist: 7-benzyl- idenenaltrexone (218) 195 Walter, J.A., see Hampson, D.R. (218) 1 Weiss, B., see Zhou, L.-W. (218) 219 Qadri, F., see Gradin, K. (218) 363 Wells, J.W., see Hampson, D.R. (218) | Welsh, S., see Zhou, L.-W. (218) 219 Ramacci, M.T., see Harsing, Jr., L.G. (218) 117 Weng, Y.-I., see Huang, H.-C. (218) 123 Ravin, R.R., see Case, C.L. (218) 213 White, F.J., see Ackerman, J.M. (218) 171 Ren, L.-M., see Iwatsuki, K. (218) 237 Whittle, B.J.R., Lopez-Belmonte, J. and Moncada, S. Ribes, G., see Hillaire-Buys, D. (218) 359 Nitric oxide mediates rat mucosal vasodilatation induced by intra- Rice, P.J., see Abraham, S.T. (218) 243 gastric capsaicin (218) 339 Rosténe, W., Boja, J.W., Scherman, D., Ivy Carroll, F. and Kuhar, Whittle, B.J.R., see Martinez-~Cuesta, M.A. (218) 351 M.J. Wienen, W., see Zhang, J. (218) 35 Dopamine transport: pharmacological distinction between the Wrathall, J.R., Bouzoukis, J. and Choiniere, D. synaptic membrane and the vesicular transporter in rat striatum Effect of kynurenate on functional deficits resulting from trau- (218) 175 matic spinal cord injury (218) 273 382 Wright, J.L.C., see Hampson, D.R. (218) 1 Zhang, S.-P., see Zhou, L.-W. (218) 219 Wu, P.H., see Mihic, S.J. (218) 283 Zharkovsky, A., see File, S.E. (218) 9 Wu, P.Y., see File, S.E. (218) 9 Zhou, L.-W., Zhang, S.-P., Welsh, S., Connell, T.A. and Weiss, B. Wu, T.-S., see Ko, F.-N. (218) 129 Triazolam blocks the initial rotational effects of quinpirole but Yamamoto, A., see Nishiyama, A. (218) 311 permits the later developing reduction of dopamine D,-mediated rotational behavior and dopamine D, receptors (218) 219 Yanagisawa, T., see Okada, Y. (218) 259 Zangrossi, Jr., H., see File, S.E. (218) 9 Zhang, J., Entzeroth, M., Wienen, W. and Van Meel, J.C.A. Characterization of BIBS 39 and BIBS 222: two new nonpeptide angiotensin II] receptor antagonists (218) 35 European Journal of Pharmacology, 218 (1992) 383-391 © 1992 Elsevier Science Publishers B.V. All rights reserved 0014-/2929 /9$059.0 0 Key word index A23187 Amine uptake Smooth muscle; Ca**; Acetylcholine; Phasic and tonic responses; IP, Dopamine; Dopamine transporters; Synaptic vesicle (Rosténe, W. (inositol trisphosphate) (Macara, B. (218) 27) (218) 175) Acetylcholine cAMP Smooth muscle; Ca**; A23187; Phasic and tonic responses; IP, Sensory C-fibers; Neurogenic inflammation; Substance P; Atypical (inositol trisphosphate) (Macara, B. (218) 27) adrenoceptors (Itabashi, S. (218) 187) GABA (y-aminobutyric acid); GABAg receptors; Neocortex; AMPA Quisqualate; (Rat) (Andre, P. (218) 137) Domoic acid; Kainic acid; Excitatory amino acid receptor; Neuro- toxin (Hampson, D.R. (218) 1) Acetyl-L-carnitine Amphetamines Brain dialysis; Dopamine release; Striatum (Harsing, Jr., L.G. (218) Basal ganglia; Dopamine; Drug abuse; Dynorphin A; 4-Methyl- 117) aminorex;, Neurotensin; 5-HT (5-hydroxytryptamine, serotonin); Sub- stance P; Tryptophan hydroxylase (Hanson, G.R. (218) 287) Acoustic startle (potentiated) WAY 100289; Light: dark box; Anxiety; 5-HT, receptor antagonists Amrinone (Bill, D.J. (218) 327) Dibutyryl cAMP; Mesenteric artery; Mesenteric vein (Itoh, H. (218) 347) Adrenaline Pancreas (isolated, rat); Pertussis toxin; Insulin secretion; a »,-Adren- Anaesthetics (intravenous) oceptors (Hillaire-Buys, D. (218) 359) Propofol; lon channels; Myelinated nerve fibre; Voltage-clamp ex- periment (Veintemilla, F. (218) 59) a -Adrenoceptors Vas deferens; Smooth muscle; Spontaneously hypertensive rats Analgesia (SHR) (Caricati-Neto, A. (218) 51) w-Conotoxin; Morphine; Withdrawal syndrome (Basilico, L. (218) 75) B-Adrenoceptors; Aorta; Jugular vein; Autoradiography; ('S1)CYP Angiotensin II ({'*Iiodo-cyanopindolol); ('>IJHEAT (('*°1][B-(4-hydroxy-3-iodo- Atrial peptides; Natriuresis; Renal perfusion pressure (Chamienia, phenyl)-ethyl-aminomethyl]-tetralone) (Killam, A.L. (218) 295) ALL. (218) 319) a ,-Adrenoceptors Angiotensin II receptor antagonists Vas deferens (rat); Protein kinase C; Phorbol esters (Abraham, S.T. BIBS 39; BIBS 222 (Zhang, J. (218) 35) (218) 243) Anterior pituitary GH,ZR, cells; Cell culture; Prolactin; Dopamine D, receptors; Vasopressin; Phosphoinositide (P1) hydrolysis; Endothelin; Nonpep- Partial agonists; Transdihydrolisuride; (+ )3-PPP (( + )-3-43-hydroxy- tide V, receptor antagonists; Ventricular myocardium (rabbit) (En- phenyl)-N-n-propylpiperidine); (In vitro) (Nilsson, C. (218) 205) doh, M. (218) 355) nones a ,-Adrenoceptors Prostaglandins; Cathartics; Diarrhoea (Nijs, G. (218) 199) Pancreas (isolated, rat); Pertussis toxin; Insulin secretion; Adrenaline (Hillaire-Buys, D. (218) 359) Antiarrhythmics Development; Electrophysiologic effect (Case, C.L. (218) 213) B-Adrenoceptors a-Adrenoceptors; Aorta; Jugular vein; Autoradiography; ['*1)}CYP Antinociception ({'>Iiodo-cyanopindolol); ['SIJHEAT ({'*1][| B-(4-hydroxy-3-iodo- 5-Opioid receptor subtypes binding; 7-Benzylidenenaltrexone phenyl)-ethyl-aminomethyl]-tetralone) (Killam, A.L. (218) 295) (BNTX) (Portoghese, P.S. (218) 195) a,-Adrenoceptor subtypes Antinociceptive effect Rilmenidine; Oxazoline; Imidazoline; Guanidinium; Cerebral cortex L-Arginine; Opiodergic system; Kyotorphin; (Rat) (Kawabata, A. (rat) (King, P.R. (218) 101) (218) 153) Aglafoline Antisecretory potency PAF receptor antagonists; ( Aglaia elliptifolia Merr) (Ko, F.-N. (218) Gastric mucosa; Prostanoids; Radioligand binding; Prostaglandin 129) receptors; Parietal cells (Hennies, S. (218) 303) 384 Anxiety Benzodiazepines WAY 100289; Light: dark box; 5-HT, receptor antagonists; Acoustic GABA (y-aminobutyric acid); 5-HT (5-hydroxytryptamine, sero- startle (potentiated) (Bill, D.J. (218) 327) tonin); 5-HT release; Hippocampus; Frontal cortex (File, $.E. (218) 9) Anxiolytic agents Aversive behaviour; R( + )-Zacopride; S(— )-Zacopride; 5-HT (S-hy- 7-Benzylid Itrexone (BNTX) droxytryptamine, serotonin); (Mouse) (Barnes, N.M. (218) 91) Antinociception; 5-Opioid receptor subtypes binding (Portoghese, P.S. (218) 195) Aorta a-Adrenoceptors; B-Adrenoceptors; Jugular vein; Autoradiography; BIBS 39 {'S1CYP ({'*Ijiodo-cyanopindolol); ['SIHEAT ({'*>1][B-(4-hy- Angiotensin Il receptor antagonists; BIBS 222 (Zhang, J. (218) 35) droxy-3-iodophenyl)-ethyl-aminomethyl]-tetralone) (Killam, A.L. (218) 295) BIBS 222 Angiotensin II receptor antagonists; BIBS 39 (Zhang, J. (218) 35) Arachidonic acid VIP (vasoactive intestinal polypeptide); Helodermin; Leukotriene Blood pressure D,; Lung (perfused, guinea-pig); Cyclo-oxygenase products (Conroy, Substance P; Dorsal raphe nucleus; 5-HT release (Gradin, K. (218) D.M. (218) 43) 363) Neutrophils; PAF (platelet-activating factor, PAF-acether); Stau- Bradykinin receptor antagonists rosporine; Phospholipase A , (Miiller, S. (218) 251) Histamine liberation; Pain measurement; Skin response (Kindgen- Milles, D. (218) 183) L-Arginine Antinociceptive effect; Opiodergic system; Kyotorphin; (Rat) (Kawabata, A. (218) 153) Brain dialysis Acetyl-L-carnitine; Dopamine release; Striatum (HarsingJ,r. , L.G. Atrial peptides (218) 117) Natriuresis; Renal perfusion pressure; Angiotensin I] (Chamienia, ALL. (218) 319) BRL 38227 Potassium channel openers; Microcirculation; Spontaneously hyper- Atrium (guinea-pig) tensive rat (SHR) (Struijker Boudier, H.A.J. (218) 191) Muscarinic receptor subtypes; Superior cervical ganglion; Ileum (guinea-pig); Drug discrimination (Arnt, J. (218) 159) Ca** Smooth muscle; Acetylcholine; A23187; Phasic and tonic responses; Atypical adrenoceptors IP, (inositol trisphosphate) (Macara, B. (218) 27) Sensory C-fibers; Neurogenic inflammation; cAMP; Substance P (Itabashi, S. (218) 187) Ca** channel antagonists Cardiovascular effects; w-Conotoxin GVIA; (Guinea-pig) (Bond, A. Autoradiography (218) 179) a-Adrenoceptors; B-Adrenoceptors; Aorta; Jugular vein; ('*1}]CYP ({'**Iiodo-cyanopindolol); ['1JHEAT ({'*1)B-(4-hydroxy-3-iodo- E4080; K* channel openers; Ca?* concentration (intracellular); pheny!)-ethyl-aminomethyl]-tetralone) (Killam, A.L. (218) 295) Vasodilators; Coronary artery (dog) (Okada, Y. (218) 259) Aversive behaviour Ca** concentration (intracellular) R(+ )-Zacopride; S(—)-Zacopride; p-Chlorophenylalanine; (Rat); E4080; K* channel openers; Ca** channel antagonists; Vasodila- (Mouse) (Barnes, N.M. (218) 15) tors; Coronary artery (dog) (Okada, Y. (218) 259) R(+ )-Zacopride; S(—)-Zacopride; Anxiolytic agents; 5-HT (5-hy- Capsaicin droxytryptamine, serotonin); (Mouse) (Barnes, N.M. (218) 91) Nitric oxide (NO); Sensory neurons; CGRP (calcitonin gene-related peptide); L-NAME (N©-nitro-L-arginine methyl ester); Gastric mu- Baclofen cosa (Whittle, B.J.R. (218) 339) Tyrosine hydroxylase; NMDA receptors; GABAg_ receptors; Dopamine synthesis; Dopaminergic transmission (Montaho, J.-A.A. (218) 335) Cardiac muscle (electrophysiology of) Taurine; Na* currents (fast); Ventricular myocytes (embryonic chick); Voltage clamp (whole-cell) (Satoh, H. (218) 83) GABA, receptor agonists; Thienyl baclofen analogs; 2-Hydroxy- saclofen; Ileum (guinea-pig, isolated) (Ong, J. (218) 343) Cardiovascular effects Basal ganglia Ca?* channel antagonists; w-Conotoxin GVIA; (Guinea-pig) (Bond, Amphetamines; Dopamine; Drug abuse; Dynorphin A; 4-Methyl- A. (218) 179) aminorex; Neurotensin; 5-HT (5-hydroxytryptamine, serotonin); Sub- stance P; Tryptophan hydroxylase (Hanson, G.R. (218) 287) Castor-oil diarrhea [D-Ala?]deltorphin II; Gastrointestinal transit; Colonic bead expul- Benzodiazepine receptors sion; (L.c.v. and i.t. administration); (Rat) (Broccardo, M. (218) 69) PET (positron emission tomography); ('*F]FEF (5-(2’-('*F]Fluoro- ethyl)flumazenil); Imaging; Flumazenil; Neuroreceptors (Moerlein, Cathartics S.M. (218) 109) Prostaglandins; Anthraquinones; Diarrhoea (Nijs, G. (218) 199) Cell culture Diazepam GH,ZR, cells; Anterior pituitary; Prolactin; Dopamine D, recep- Emotionality; GABA (y-aminobutyric acid); Pentobarbital; Cl” flux: tors; Partial agonists; Transdihydrolisuride; (+ )3-PPP (( + )-3-(3-hy- (Mouse) (Mihic, S.J. (218) 283) droxyphenyl)-N-n-propylpiperidine); (In vitro) (Nilsson, C. (218) 205) Dibutyry! cAMP Cerebral cortex (rat) Amrinone; Mesenteric artery; Mesenteric vein (Itoh, H. (218) 347) Rilmenidine; Oxazoline; Imidazoline; Guanidinium; aj-Adrenocep- tor subtypes (King, P.R. (218) 101) Domoic acid Kainic acid; AMPA; Excitatory amino acid receptor; Neurotoxin CGRP (calcitonin gene-related peptide) (Hampson, D.R. (218) 1) Nitric oxide (NO); Capsaicin; Sensory neurons; L-NAME (N“©-nitro- L-arginine methyl ester); Gastric mucosa (Whittle, B.J.R. (218) 339) Dopamine Dopamine transporters; Synaptic vesicle; Amine uptake (Rosténe, ‘Sel. hh lal ‘ nor W. (218) 175) R( + )-Zacopride; S(—)-Zacopride; Aversive behaviour; (Rat); (Mouse) (Barnes, N.M. (218) 15) Amphetamines; Basal ganglia; Drug abuse; Dynorphin A; 4-Methyl- aminorex; Neurotensin; 5-HT (S-hydroxytryptamine, serotonin); Sub- Cisplatin stance P; Tryptophan hydroxylase (Hanson, G.R. (218) 287) 5-HT, receptor antagonists; Zacopride; GR38032F; Dexamethasone; Taste aversion (conditioned) (Mele, P.C. (218) 229) Dopamine D, receptors; Neuroleptics (Schotte, A. (218) 373) Cl~ flux Dopamine neurons Emotionality, GABA (y-aminobutyric acid); Diazepam; Pentobarbi- Cocaine; Withdrawal; Ventral tegmental area; Electrophysiology tal; (Mouse) (Mihic, S.J. (218) 283) (Ackerman, J.M. (218) 171) Cocaine Dopamine D, receptor agonists Dopamine neurons; Withdrawal; Ventral tegmental area; Electro- Pancreas (dog); Exocrine secretion; YM435 (Iwatsuki, K. (218) 237) physiology (Ackerman, J.M. (218) 171) Dopamine receptors Colonic bead expulsion Down-regulation; Triazolam; GABA (y-aminobutyric acid); Quinpi- [D-Ala?}deltorphin I]; Castor-oil diarrhea; Gastrointestinal transit; role; 6-Hydroxydopamine (6-OHDA) (Zhou, L.-W. (218) 219) (L.c.v. and i.t. administration); (Rat) (Broccardo, M. (218) 69) Dopamine D, receptors w -Conotoxin GH,ZR, cells; Cell culture; Anterior pituitary; Prolactin; Partial Morphine; Analgesia; Withdrawal syndrome (Basilico, L. (218) 75) agonists; Transdihydrolisuride; (+ )3-PPP (( + )-3-(3-hydroxypheny!)- N-n-propylpiperidine); (In vitro) (Nilsson, C. (218) 205) w-Conotoxin GVIA Ca’* channel antagonists; Cardiovascular effects; (Guinea-pig) Dopamine D, receptors (Bond, A. (218) 179) Dopamine; Neuroleptics (Schotte, A. (218) 373) Coronary artery (dog) E4080; K* channel openers; Ca** channel antagonists; Ca?* con- Dopamine release Acetyl-L-carnitine; Brain dialysis; Striatum (HarsingJ,r ., L.G. (218) centration (intracellular); Vasodilators (Okada, Y. (218) 259) 117) Cyc! v-oxygenase products VIP (vasoactive intestinal polypeptide); Helodermin; Leukotriene Dopaminergic transmission D,; Arachidonic acid; Lung (perfused, guinea-pig) (Conroy, D.M. Tyrosine hydroxylase; NMDA receptors; GABA, receptors; Ba- clofen; Dopamine synthesis (Montano, J.-A.A. (218) 335) (218) 43) ["*51)CYP ({'*51iedo-cyanopindolol) Dopamine synthesis a-Adrenoceptors; B-Adrenoceptors; Aorta; Jugular vein; Autoradio- Tyrosine hydroxylase; NMDA receptors; GABA, receptors; Ba- graphy; ['SIJHEAT ({'?>1][ B-(4-hydroxy-3-iodophenyl)-ethyl- clofen; Dopaminergic transmission (Montano, J.-A.A. (218) 335) aminomethyl}-tetralone) (Killam, A.L. (218) 295) Dopamine transporters [D-Ala? |deltorphin II Dopamine; Synaptic vesicle; Amine uptake (Rosténe, W. (218) 175) Castor-oil diarrhea; Gastrointestinal transit; Colonic bead expulsion; (L.c.v. and i.t. administration); (Rat) (Broccardo, M. (218) 69) Dorsal raphe nucleus Substance P; 5-HT release; Blood pressure (Gradin, K. (218) 363) Development Antiarrhythmics; Electrophysiologic effect (Case, C.L. (218) 213) Down-regulation Triazolam; GABA (y-aminobutyric acid); Dopamine receptors; Dexamethasone Quinpirole; 6-Hydroxydopamine (6-OHDA) (Zhou, L.-W. (218) 219) 5-HT, receptor antagonists; Zacopride; GR38032F; Cisplatin; Taste aversion (conditioned) (Mele, P.C. (218) 229) Drug abuse Amphetamines; Basal ganglia; Dopamine; Dynorphin A; 4-Methyl- Diarrhoea aminorex; Neurotensin; 5-HT (5-hydroxytryptamine, serotonin), Sub- Prostaglandins; Anthraquinones; Cathartics (Nijs, G. (218) 199) stance P; Tryptophan hydroxylase (Hanson, G.R. (218) 287) 386 Drug discrimination Frontal cortex Muscarinic receptor subtypes; Superior cervical ganglion; Ileum GABA (y-aminobutyric acid); 5-HT (S-hydroxytryptamine, sero- (guinea-pig); Atrium (guinea-pig) (Arnt, J. (218) 159) tonin); 5-HT release; Hippocampus; Benzodiazepines (File, S.E. (218) 9) DuP753 Semotiadil; Glomerular filtration rate; Renal blood flow; Renin- GABA (y-aminobutyric acid) angiotensin system (Nishiyama, A. (218) 311) 5-HT (5-hydroxytryptamine, serotonin); 5-HT release; Hippocampus; Frontal cortex; Benzodiazepines (File, $.E. (218) 9) Dynorphin A Amphetamines; Basal ganglia; Dopamine; Drug abuse; 4-Methyl- GABA, receptors; Neocortex; Acetylcholine; Quisqualate; (Rat) aminorex; Neurotensin; 5-HT (5-hydroxytryptamine, serotonin); Sub- (Andre, P. (218) 137) stance P; Tryptophan hydroxylase (Hanson, G.R. (218) 287) Down-regulation; Triazolam; Dopamine receptors; Quinpirole; 6-Hy- E4080 droxydopamine (6-OHDA) (Zhou, L.-W. (218) 219) K* channel openers; Ca?* + channel antagonists; Ca** concentration (intracellular); Vasodilators; Coronary artery (dog) (Okada, Y. (218) Emotionality; Diazepam; Pentobarbital; Cl flux; (Mouse) (Mihic, 259) S.J. (218) 283) Electrophysiologic effect GABA, receptor agonists Antiarrhythmics; Development (Case, C.L. (218) 213) Baclofen; Thienyl baclofen analogs; 2-Hydroxysaclofen; Ileum (guinea-pig, isolated) (Ong, J. (218) 343) Electrophysiology Cocaine; Dopamine neurons; Withdrawal; Ventral tegmental area GABA, receptors (Ackerman, J.M. (218) 171) GABA (y-aminobutyric acid); Neocortex; Acetylcholine; Quisqualate; (Rat) (Andre, P. (218) 137) Emotionality GABA (y-aminobutyric acid); Diazepam; Pentobarbital; Cl” flux; Tyrosine hydroxylase; NMDA receptors; Baclofen; Dopamine syn- (Mouse) (Mihic, S.J. (218) 283) thesis; Dopaminergic transmission (Montano, J.-A.A. (218) 335) Endothelin Gastric acid Vasopressin; Phosphoinositide (PI) hydrolysis; a,-Adrenoceptors; Endotoxin; PAF (platelet-activating factor, PAF-acether); Nitric ox- Nonpeptide V, receptor antagonists; Ventricular myocardium (rab- ide (NO); Pentagastrin (Martinez-Cuesta, M.A. (218) 351) bit) (Endoh, M. (218) 355) Gastric mucosa Endotoxin Prostanoids; Radioligand binding; Prostaglandin receptors; Parietal Gastric acid; PAF (platelet-activating factor, PAF-acether); Nitric cells; Antisecretory potency (Hennies, S. (218) 303) oxide (NO); Pentagastrin (Martinez-Cuesta, M.A. (218) 351) Nitric oxide (NO); Capsaicin; Sensory neurons; CGRP (calcitonin Excitatory amino acid receptor gene-related peptide); L-NAME (N°-nitro-L-arginine methyl! ester) Domoic acid; Kainic acid; AMPA; Neurotoxin (Hampson, D.R. (218) (Whittle, B.J.R. (218) 339) 1) Gastrointestinal transit Excitatory amino acids [D-Ala?]deltorphin Il; Castor-oil diarrhea; Colonic bead expulsion; Spinal cord contusion; NMDA receptor antagonists; Non-NMDA (L.c.v. and i.t. administration); (Rat) (Broccardo, M. (218) 69) receptor antagonists (Wrathall, J.R. (218) 273) GH,ZR,, cells Excitotoxicity Cell culture; Anterior pituitary; Prolactin; Dopamine D, receptors; Glycine; NMDA receptors; Kynurenates; Thiokynurenates; Ischemia Partial agonists; Transdihydrolisuride; (+ )3-PPP (( + )-3-(3-hydroxy- (Moroni, F. (218) 145) phenyl)-N-n-propylpiperidine); (In vitro) (Nilsson, C. (218) 205) Exocrine secretion Glomerular filtration rate Pancreas (dog); YM435; Dopamine D, receptor agonists (Iwatsuki, Semotiadil; DuP753; Renal blood flow; Renin—angiotensin system K. (218) 237) (Nishiyama, A. (218) 311) ('*FJFEF (5-(F] F2luo'roet-hy![)fl'umaz*eni l) Glycine Benzodiazepine receptors; PET (positron emission tomography); NMDA receptors; Kynurenates; Thiokynurenates; Ischemia; Excito- Imaging; Flumazenil; Neuroreceptors (Moerlein, $.M. (218) 109) toxicity (Moroni, F. (218) 145) Flumazenil GR38032F Benzodiazepine receptors; PET (positron emission tomography); 5-HT, receptor antagonists; Zacopride; Dexamethasone; Cisplatin; ('SFJFEF (5-(2’-{'*F]Fluoroethyl)flumazenil); Imaging; Neurorecep- Taste aversion (conditioned) (Mele, P.C. (218) 229) tors (Moerlein, $.M. (218) 109) Guanidinium Free radical scavenger Rilmenidine; Oxazoline; Imidazoline; a -Adrenoceptor subtypes; Vasodilator effect; Scoparone (Huang, H.-C. (218) 123) Cerebral cortex (rat) (King, P.R. (218) 101) (?S1)HEAT (('*51}[8-(4-hydroxy-3-iodophenyl)-ethyl-aminometh- Imaging yl)-tetralone) Benzodiazepine receptors; PET (positron emission tomography); a-Adrenoceptors; B-Adrenoceptors; Aorta; Jugular vein; Autoradio- ('SFJFEF (5-(2’-['*F]Fluoroethyl)flumazenil); Flumazenil; Neurore- graphy; ['*1)CYP ({'**Iiodo-cyanopindolol) (Killam, A.L. (218) 295) ceptors (Moerlein, $.M. (218) 109) Helodermin Imidazoline VIP (vasoactive intestinal polypeptide); Leukotriene D,; Arachidonic Rilmenidine; Oxazoline; Guanidinium; a -Adrenoceptor subtypes; acid; Lung (perfused, guinea-pig); Cyclo-oxygenase products (Con- Cerebral cortex (rat) (King, P.R. (218) 101) roy, D.M. (218) 43) Insulin secretion Hippocampus Pancreas (isolated, rat); Pertussis toxin; Adrenaline; a>-Adrenocep- GABA (y-aminobutyric acid); 5-HT (5-hydroxytryptamine, sero- tors (Hillaire-Buys, D. (218) 359) tonin); 5-HT release; Frontal cortex; Benzodiazepines (File, S.E. (218) 9) lon channels Propofol; Myelinated nerve fibre; Voltage-clamp experiment; Anaes- Histamine liberation thetics (intravenous) (Veintemilla, F. (218) 59) Bradykinin receptor antagonists; Pain measurement; Skin response IP, (inositol trisphosphate) (Kindgen-Milles, D. (218) 183) Smooth muscle; Ca**; Acetylcholine; A23187; Phasic and tonic H *,K *-ATPase responses (Macara, B. (218) 27) Omeprazole; Pantoprazole (Beil, W. (218) 265) Ischemia 13-HODE (13-hydroxyoctadecadienoic acid) Glycine; NMDA receptors; Kynurenates; Thiokynurenates; Excito- Oedema formation; Leukotriene B,; Skin (rabbit) (Buckley, T.L. toxicity (Moroni, F. (218) 145) (218) 369) Jugular vein 5-HT (5-hydroxytryptamine, serotonin) a-Adrenoceptors; $-Adrenoceptors; Aorta; Autoradiography; GABA (y-aminobutyric acid); 5-HT release; Hippocampus; Frontal ['1)CYP ({'**Iiodo-cyanopindolol), ['*IJHEAT ({'**1,B-44-hy- cortex; Benzodiazepines (File, S.E. (218) 9) droxy-3-iodophenyl)-ethyl-aminomethyl]-tetralone) (Killam, A.L. (218) 295) Aversive behaviour; R(+)-Zacopride; S(—)-Zacopride; Anxiolytic agents; (Mouse) (Barnes, N.M. (218) 91) Kainic acid Domoic acid; AMPA; Excitatory amino acid receptor; Neurotoxin Amphetamines; Basal ganglia; Dopamine; Drug abuse; Dynorphin (Hampson, D.R. (218) 1) A; 4-Methylaminorex; Neurotensin; Substance P; Tryptophan hy- droxylase (Hanson, G.R. (218) 287) K* channel openers E4080; Ca?* channel antagonists; Ca2* concentration (intracellular); 5-HT, receptor antagonists Vasodilators; Coronary artery (dog) (Okada, Y. (218) 259) Zacopride; GR38032F; Dexamethasone; Cisplatin; Taste aversion (conditioned) (Mele, P.C. (218) 229) Kynurenates Glycine; NMDA receptors; Thiokynurenates; Ischemia; Excitotoxic- WAY 100289; Light: dark box; Anxiety; Acoustic startle (potentiated) ity (Moroni, F. (218) 145) (Bill, D.J. (218) 327) Kyotorphin 5-HT release L-Arginine; Antinociceptive effect; Opiodergic system; (Rat) GABA (y-aminobutyric acid); 5-HT (5-hydroxytryptamine, sero- (Kawabata, A. (218) 153) tonin); Hippocampus; Frontal cortex; Benzodiazepines (File, S.E. (218) 9) Leukotriene B, 13-HODE (13-hydroxyoctadecadienoic acid); Oedema formation; Substance P; Dorsal raphe nucleus; Blood pressure (Gradin, K. (218) Skin (rabbit) (Buckley, T.L. (218) 369) 363) Leukotriene D, 6-Hydroxydopamine (6-OHDA) VIP (vasoactive intestinal polypeptide); Helodermin; Arachidonic Down-regulation; Triazolam; GABA (y-aminobutyric acid); Dop- acid; Lung (perfused, guinea-pig); Cyclo-oxygenase products (Con- amine receptors; Quinpirole (Zhou, L.-W. (218) 219) roy, D.M. (218) 43) 2-Hydroxysaclofen Lig:h dtar k box Baclofen; GABA , receptor agonists; Thienyl baclofen analogs; Ileum WAY 100289; Anxiety; 5-HT, receptor antagonists; Acoustic startle (guinea-pig, isolated) (Ong, J. (218) 343) (potentiated) (Bill, D.J. (218) 327) Hleum (guinea-pig) Lung (perfused, guinea-pig) Muscarinic receptor subtypes; Superior cervical ganglion; Atrium VIP (vasoactive intestinal polypeptide); Helodermin; Leukotriene (guinea-pig); Drug discrimination (Arnt, J. (218) 159) D,; Arachidonic acid; Cyclo-oxygenase products (Conroy, D.M. (218) 43) lleum (guinea-pig, isolated) Baclofen; GABA, receptor agonists; Thienyl baclofen analogs; 2- Mesenteric artery Hydroxysaclofen (Ong, J. (218) 343) Amrinone; Dibutyryl cAMP; Mesenteric vein (Itoh, H. (218) 347) 388 Mesenteric vein Nitric oxide (NO) Amrinone; Dibutyryl cAMP; Mesenteric artery (Itoh, H. (218) 347) Stroke; Neuroprotection (Trifiletti, R.R. (218) 197) 4-Methylaminorex Capsaicin; Sensory neurons; CGRP (calcitonin gene-related peptide); Amphetamines; Basal ganglia; Dopamine; Drug abuse; Dynorphin L-NAME (N°-nitro-L-arginine methyl ester); Gastric mucosa (Whit- A; Neurotensin; 5-HT (5-hydroxytryptamine, serotonin); Substance tle, B.J.R. (218) 339) P; Tryptophan hydroxylase (Hanson, G.R. (218) 287) Gastric acid; Endotoxin; PAF (platelet-activating factor, PAF- Microcirculation acether); Pentagastrin (Martinez-Cuesta, M.A. (218) 351) BRL 38227; Potassium channel openers; Spontaneously hypertensive rat (SHR) (Struijker Boudier, H.A.J. (218) 191) NMDA receptor antagonists Spinal cord contusion; Non-NMDA receptor antagonists; Excitatory Morphine amino acids (Wrathall, J.R. (218) 273) w-Conotoxin; Analgesia; Withdrawal syndrome (Basilico, L. (218) 75) NMDA receptors Muscarinic receptor subtypes Glycine; Kynurenates; Thiokynurenates; Ischemia; Excitotoxicity Superior cervical ganglion; Ileum (guinea-pig); Atrium (guinea-pig); (Moroni, F. (218) 145) Drug discrimination (Arnt, J. (218) 159) Tyrosine hydroxylase; GABA, receptors; Baclofen; Dopamine syn- Myelinated nerve fibre thesis; Dopaminergic transmission (Montano, J.-A.A. (218) 335) Propofol; Ion channels; Voltage-clamp experiment; Anaesthetics (in- travenous) (Veintemilla, F. (218) 59) Non-NMDA receptor antagonists Na* currents (fast) Spinal cord contusion; NMDA receptor antagonists; Excitatory amino Taurine; Ventricular myocytes (embryonic chick); Voltage clamp acids (Wrathall, J.R. (218) 273) (whole-cell); Cardiac muscle (electrophysiology of) (Satoh, H. (218) 83) Nonpeptide V, receptor antagonists Vasopressin; Phosphoinositide (PI) hydrolysis; a@,-Adrenoceptors; L-NAME (N®- nitro-L-arginine methyl ester) Endothelin; Ventricular myocardium (rabbit) (Endoh, M. (218) 355) Nitric oxide (NO); Capsaicin; Sensory neurons; CGRP (calcitonin gene-related peptide); Gastric mucosa (Whittle, B.J.R. (218) 339) Oedema formation 13-HODE (13-hydroxyoctadecadienoic acid); Leukotriene B,; Skin Natriuresis (rabbit) (Buckley, T.L. (218) 369) Atrial peptides; Renal perfusion pressure; Angiotensin II (Chamienia, A.L. (218) 319) Omeprazole H*,K*-ATPase; Pantoprazole (Beil, W. (218) 265) Neocortex GABA (y-aminobutyric acid); GABA, receptors; Acetylcholine; Opiodergic system Quisqualate; (Rat) (Andre, P. (218) 137) L-Arginine; Antinociceptive effect; Kyotorphin; (Rat) (Kawabata, A. (218) 153) Neurogenic inflammation Sensory C-fibers; cAMP; Substance P; Atypical adrenoceptors 5-Opioid receptor subtypes binding (Itabashi, S. (218) 187) Antinociception; 7-Benzylidenenaltrexone (BNTX) (Portoghese, P.S. (218) 195) Neuroleptics Dopamine; Dopamine D, receptors (Schotte, A. (218) 373) Oxazoline Rilmenidine; Imidazoline; Guanidinium; a ,-Adrenoceptor subtypes; Neuroprotection Cerebral cortex (rat) (King, P.R. (218) 101) Nitric oxide (NO); Stroke (Trifiletti, R.R. (218) 197) PAF (platelet-activating factor, PAF-acether) Neuroreceptors Neutrophils; Arachidonic acid; Staurosporine; Phospholipase A, Benzodiazepine receptors; PET (positron emission tomography); {'*FJFEF (5-(2'-['® F]JFluoroethy!)- (Miller, S. (218) 251) flumazenil); Imaging; Flumazenil (Moeriein, $.M. (218) 109) Gastric acid; Endotoxin; Nitric oxide (NO); Pentagastrin (Martinez- Neurotensin Cuesta, M.A. (218) 351) Amphetamines; Basal ganglia; Dopamine; Drug abuse; Dynorphin A; 4-Methylaminorex; 5-HT (5-hydroxytryptamine, serotonin); Sub- PAF receptor antagonists stance P; Tryptophan hydroxylase (Hanson, G.R. (218) 287) Aglafoline; ( Aglaia elliptifolia Merr) (Ko, F.-N. (218) 129) Neurotoxin Pain measurement Domoic acid; Kainic acid; AMPA; Excitatory amino acid receptor Bradykinin receptor antagonists; Histamine liberation; Skin response (Hampson, D.R. (218) 1) (Kindgen-Milles, D. (218) 183) Neutrophils Pancreas (dog) Arachidonic acid; PAF (platelet-activating factor, PAF-acether); Exocrine secretion; YM435; Dopamine D, receptor agonists Staurosporine; Phospholipase A , (Miiller, S. (218) 251) (Iwatsuki, K. (218) 237)

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