European Journal of Pharmacology 1991: Vol 206 Index

12 Pages·1991·3.8 MB·English

European Journal of Pharmacology — Molecular Pharmacology Section, 206 (1991) 351-353 351
© 1991 Elsevier Science Publishers B.V. 0922-4106 /91/$03.50
Author index
Abdel-Latif, A.A., see Akhtar, R.A. (206) 291 Falcone, R.C. and Aharony, D.
Agullé, L. and Garcia, A. Modulation of affinity and density of LTB, receptors on guinea
Norepinephrine increases cyclic GMP in astrocytes by a mecha- pig lung membranes by divalent cations and guanine nucleotides
nism dependent on nitric oxide synthesis (206) 343 (206) 333
Aharony, D., see Falcone, R.C. (206) 333 Fertel, R.H., see Xia, Y. (206) 231
Akhtar, R.A. and Abdel-Latif, A.A. Frew, R., see Lundy, P.M. (206) 61
The effect of M&B 22948 on carbachol-induced inositol tri- Fille, H.-J., Heim, J.-M. and Gerzer, R.
sphosphate accumulation and contraction in iris sphincter smooth Functional modulation of ANF-sensitive particulate guanylate
muscle (206) 291 cyclase by redox mechanisms (206) 69
Allgaier, C., see Huang, H.Y. (206) 221 Fuller, T.W., see Lundy, P.M. (206) 61
Andersen, P.H., Juhl, H., Pedersen, S.B. and Richelsen, B.
Phosphoinositide metabolism in adipocytes from hypothyroid rats
Galitzky, J., see Larrouy, D. (206) 139
(206) 81
Garcia, A., see Agullé, L. (206) 343
Garcia-Sainz, J.A., see Torres-Marquez, M.E. (206) 199
Baidan, L.V., see Xia, Y. (206) 231 Gerzer, R., see Fille, H.-J. (206) 69
Barnard, E.A., see Shingai, R. (206) 77 Gierschik, P., see Reithmann, C. (206) 53
Barnes, P.J., see Hamid, Q.A. (206) 133 Glibert, F., see Couraud, P.-O. (206) 191
Baron, B.M., Siegel, B.W., Slone, A.L., Harrison, B.L., Palfreyman, Goldblum, A. and Loew, G.H.
M.G. and Hurt, S.D. A molecular model for an anionic opiate p-receptor: affinity and
[°H]5,7-Dichlorokynurenic acid, a novel radioligand labels NUDA activation of morphine conformers (206) 119
receptor-associated glycine binding sites (206) 149 Gommeren, W., see Leysen, J.E. (206) 39
Barthelmebs, M., see Grima, M. (206) 203 Greil, W., see Van Calker, D. (206) 285
Baumann, D., see Lester, D.S. (206) 301 Grima, M., Mosser, J., Welsch, C., Barthelmebs, M. and Imbs, J.-L.
Bitran, J.A., see Manji, H.K. (206) 159 (*H]Ramiprilat binding to the angiotensin-converting enzyme in
Bockaert, J., see Schmidt, B.H. (206) 87 rat renal brush-border membranes: the effect of chloride (206) 203
Bormann, J., see Kornhuber, J. (206) 297 Guérineau, N., see Mollard, P. (206) 271
Gusovsky, F., Soergel, D.G. and Daly, J.W.
Effects of mastoparan and related peptides on phosphoinositide
Camus, J., see Waelbroeck, M. (206) 95
breakdown in HL-60 cells and cell-free preparations (206) 309
Challiss, R.A.J., see Whitham, E.M. (206) 181
Gusovsky, F., see Manji, H.K. (206) 159
Chen, G., see Manji, H.K. (206) 159
Chiavaroli, C., see Mollard, P. (206) 271
Chrétien, Y., see Lachaud-Pettiti, V. (206) 23 Hadamovsky, S., see Entzeroth, M. (206) 237
Christophe, J., see Waelbroeck, M. (206) 95 Halushka, P.V., see Mayeux, P.R. (206) 15
Colucci, W.S., see Sperti, G. (206) 279 Hamid, Q.A., Mak, J.C.W., Sheppard, M.N., Corrin, B., Venter, J.C.
Cooper, D.M.F., see Mollard, P. (206) 271 and Barnes, P.J.
Corrin, B., see Hamid, Q.A. (206) 133 Localization of B,-adrenoceptor messenger RNA in human and
Couraud, P.-O., Durieu-Trautmann, O., Le Nguyen, D., Marin, P., rat lung using in situ hybridization: correlation with receptor
Glibert, F. and Strosberg, A.D. autoradiography (206) 133
Functional endothelin-1 receptors in rat astrocytoma C6 (206) 191 Hamilton, M.G., see Lundy, P.M. (206) 61
Cusack, B., Stanton, T. and Richelson, E. Harrison, B.L., see Baron, B.M. (206) 149
Developmental regulation of neurotensin receptor expression and Hattori, R., see Hiki, K. (206) 163
function in murine neuroblastoma clone N1E-115 (206) 339 Heim, J.-M., see Fiille, H.-J. (206) 69
Henderson, A.K., Yamamura, H.I., Maggi, C.A., Roeske, W.R. and
Smith, T.L.
Daly, J.W., see Gusovsky, F. (206) 309
Neurokinin A receptors are coupled to calcium mobilization in
De Costa, B.R., see Moody, E.J. (206) 113
transfected fibroblasts (206) 251
Dragunow, M., Logan, B. and Laverty, R.
Hertting, G., see Huang, H.Y. (206) 221
3,4-Methylenedioxymethamphetamine induces Fos-like proteins in
Hiki, K., Yui, Y., Hattori, R., Eizawa, H., Kosuga, K. and Kawai, C.
rat basal ganglia: reversal with MK 801 (206) 255
Three regulation mechanisms of nitric oxide synthase (206) 163
Durieu-Trautmann, O., see Couraud, P.-O. (206) 191
Huang, H.Y., Hertting, G., Allgaier, C. and Jackisch, R.
3,4-Diaminopyridine-evoked noradrenaline release in rat hippo-
Eizawa, H., see Hiki, K. (206) 163 campus: role of Na* entry on Ca** pools and of protein kinase C
Entzeroth, M. and Hadamovsky, S. (206) 221
Angiotensin II receptors in the rat lung are of the AII-1 subtype Hiibers, M., see Kornhuber, J. (206) 297
(206) 237 Hurt, S.D., see Baron, B.M. (206) 149
352
IJzerman, A.P., see Van der Wenden, E.M. (206) 315 Manzoni, O.J.J., see Schmidt, B.H. (206) 87
Imaizumi, T., see Kawamoto, H. (206) 33 Marin, P., see Couraud, P.-O. (206) 191
Imbs, J.-L., see Grima, M. (206) 203 Mayeux, P.R., Mais, D.E. and Halushka, P.V.
Iwasaki, T., see Kawamoto, H. (206) 33 Interactions of dihydropyridine Ca** channel agonists with the
human platelet thromboxane A,/prostaglandin H, receptor (206)
Jackisch, R., see Huang, H.Y. (206) 221 15
Jakobs, K.H., see Reithmann, C. (206) 53 Mellerup, E.T., see Plenge, P. (206) 243
Janssen, P.A.J., see Leysen, J.E. (206) 39 Mollard, P., Guérineau, N., Chiavaroli, C., Schlegel, W. and Cooper,
Juhl, H., see Andersen, P.H. (206) 81 D.M.F.
Adenosine A, receptor-induced inhibition of Ca** transients lin-
Kanaide, H., see Yamamoto, H. (206) 175 ked to action potentials in clonal pituitary cells (206) 271
Kawai, C., see Hiki, K. (206) 163 Moody, E.J., Lewin, A.H., De Costa, B.R., Rice, K.C. and Skolnick,
Kawamoto, H., Watanabe, Y., Imaizumi, T., Iwasaki, T. and Yoshida, FP,
H. Site-specific acylation of GABA-gated Cl~™ channels: effects on
*°Cl~ uptake (206) 113
Effects of lithium ion on ADP ribosylation of inhibitory GTP-
binding protein by pertussis toxin, islet-activating protein (206) 33 Morgan, D.W., see Letari, O. (206) 211
Klotz, K.-N., see Van Calker, D. (206) 285 Mosser, J., see Grima, M. (206) 203
Komas, N., Le Bec, A., Stoclet, J.-C. and Lugnier, C. Musacchio, J.M., see Zhou, G.-Z. (206) 261
Cardiac cGMP-stimulated cyclic nucleotide phosphodiesterases: Mutschler, E., see Waelbroeck, M. (206) 95
effects of cGMP analogues and drugs (206) 5
Kondo, Y., see Nazarea, M. (206) 47 Nahorski, S.R., see Whitham, E.M. (206) 181
Kornhuber, J., Bormann, J., Hiibers, M., Rusche, K. and Riederer, P. Nakamura, M., see Yamamoto, H. (206) 175
Effects of the 1-amino-adamantanes at the MK-801-binding site of Nazarea, M., Okajima, F. and Kondo, Y.
the NMDA-receptor-gated ion channel: a human postmortem P,-purinergic activation of phosphoinositide turnover is potenti-
brain study (206) 297 ated by A,-receptor stimulation in thyroid cells (206) 47
Kosuga, K., see Hiki, K. (206) 163 Nicosia, S., see Letari, O. (206) 211
Lachaud-Pettiti, V., Podevin, R.-A., Chrétien, Y. and Parini, A. Okajima, F., see Nazarea, M. (206) 47
Imidazoline-guanidinium and a,-adrenergic binding sites in baso- Orsetti, M. and Sorba, G.
lateral membranes from human kidney (206) 23 Characterization of an accessory binding area in the histamine H,
Lafontan, M., see Larrouy, D. (206) 139 receptor (206) 167
Lambrecht, G., see Waelbroeck, M. (206) 95
Larrouy, D., Galitzky, J. and Lafontan, M. Palfreyman, M.G., see Baron, B.M. (206) 149
A, adenosine receptors in the human fat cell: tissue distribution Parini, A., see Lachaud-Pettiti, V. (206) 23
and regulation of radioligand binding (206) 139 Pedersen, S.B., see Andersen, P.H. (206) 81
Laursen, H., see Plenge, P. (206) 243 Plenge, P., Mellerup, E.T. and Laursen, H.
Laverty, R., see Dragunow, M. (206) 255 Affinity modulation of [*H]imipramine, [*H]paroxetine and [*H]-
Le Bec, A., see Komas, N. (206) 5 citalopram binding to the 5-HT transporter from brain and plate-
Le Nguyen, D., see Couraud, P.-O. (206) 191 lets (206) 243
Lester, D.S. and Baumann, D. Podevin, R.-A., see Lachaud-Pettiti, V. (206) 23
Action of organic solvents on protein kinase C (206) 301 Potter, W.Z., see Manji, H.K. (206) 159
Letari, O., Malgaroli, A., Morgan, D.W., Welton, A.F. and Nicosia, S. Pullan, L.M., see Stumpo, R.J. (206) 155
Cytosolic calcium ion and arachidonic acid release and metabo-
lism in macrophages (206) 211 Reithmann, C., Gierschik, P., Werdan, K. and Jakobs, K.H.
Lewin, A.H., see Moody, E.J. (206) 113 Tumor necrosis factor a up-regulates G,, and Gg proteins and
Leysen, J.E., Gommeren, W. and Janssen, P.A.J. adenylyl cyclase responsiveness in rat cardiomyocytes (206) 53
Identification of non-serotonergic [*H]ketanserin binding sites on Rice, K.C., see Moody, E.J. (206) 113
human platelets and their role in serotonin release (206) 39 Richelsen, B., see Andersen, P.H. (206) 81
Li, P.P., Tam, Y.-K., Young, L.T. and Warsh, J.J. Richelson, E., see Cusack, B. (206) 339
Lithium decreases Gs, Gi-1 and Gi-2 a-subunit mRNA levels in Riederer, P., see Kornhuber, J. (206) 297
rat cortex (206) 165 Roeske, W.R., see Henderson, A.K. (206) 251
Loew, G.H., see Goldblum, A. (206) 119 Royer, M., see Schmidt, B.H. (206) 87
Logan, B., see Dragunow, M. (206) 255 Rusche, K., see Kornhuber, J. (206) 297
Long, J.P., see Sheff, K.Y. (206) 105
Lugnier, C., see Komas, N. (206) 5 Salama, A.I., see Stumpo, R.J. (206) 155
Lugnier, C., see Schaeffer, P. (206) 325 Schaeffer, P., Lugnier, C. and Stoclet, J.-C.
Lundy, P.M., Frew, R., Fuller, T.W. and Hamilton, M.G. Interactions of calmodulin antagonists with calcium antagonists
Pharmacological evidence for an w-conotoxin, dihydropyridine-in- binding sites (206) 325
sensitive neuronal Ca** channel (206) 61 Schlegel, W., see Mollard, P. (206) 271
Schmidt, B.H., Manzoni, O.J.J., Royer, M., Bockaert, J. and Sladec-
Maggi, C.A., see Henderson, A.K. (206) 251 zek, F.A.J.
Mais, D.E., see Mayeux, P.R. (206) 15 Cholinergic inositol phosphate formation in striatal neurons is
Mak, J.C.W., see Hamid, Q.A. (206) 133 mediated by distinct mechanisms (206) 87
Malgaroli, A., see Letari, O. (206) 211 Sheff, K.Y., Yorek, M.A. and Long, J.P.
Manji, H.K., Chen, G., Bitran, J.A., Gusovsky, F. and Potter, W.Z. Hemicholinium-3 derivatives A-4 and A-5 affect choline and
Chronic exposure of C6 glioma cells to desipramine desensitizes acetylcholine metabolism (206) 105
B-adrenoceptors, but increases K; /Ky, ratio (206) 159 Sheppard, M.N., see Hamid, Q.A. (206) 133
Shingai, R., Sutherland, M.L. and Barnard, E.A. Van Galen, P.J.M., see Van der Wenden, E.M. (206) 315
Effects of subunit types of the cloned GABA, receptor on the Venter, J.C., see Hamid, Q.A. (206) 133
response to a neurosteroid (206) 77 Villalobos-Molina, R., see Torres-Marquez, M.E. (206) 199
Siegel, B.W., see Baron, B.M. (206) 149
Skolnick, P., see Moody, E.J. (206) 113
Sladeczek, F.A.J., see Schmidt, B.H. (206) 87 Waelbroeck, M., Camus, J., Tastenoy, M., Mutschler, E., Strohmann,
C., Tacke, R., Lambrecht, G. and Christophe, J.
Slone, A.L., see Baron, B.M. (206) 149
Binding affinities of hexahydro-difenidol and hexahydro-sila-dif-
Smith, T.L., see Henderson, A.K. (206) 251
Soergel, D.G., see Gusovsky, F. (206) 309 enidol analogues at four muscarinic receptor subtypes: constitu-
tional and stereochemical aspects (206) 95
Sorba, G., see Orsetti, M. (206) 167
Warsh, J.J., see Li, P.P. (206) 165
Soudijn, W., see Van der Wenden, E.M. (206) 315
Watanabe, Y., see Kawamoto, H. (206) 33
Sperti, G. and Colucci, W.S.
Calcium influx modulates DNA synthesis and proliferation in Welsch, C., see Grima, M. (206) 203
Welton, A.F., see Letari, O. (206) 211
A,r, vascular smooth muscle cells (206) 279
Werdan, K., see Reithmann, C. (206) 53
Stanton, T., see Cusack, B. (206) 339
Whitham, E.M., Challiss, R.A.J. and Nahorski, S.R.
Steber, R., see Van Calker, D. (206) 285
M, muscarinic cholinoceptors are linked to phosphoinositide
Stoclet, J.-C., see Komas, N. (206) 5
metabolism in rat cerebellar granule cells (206) 181
Stoclet, J.-C., see Schaeffer, P. (206) 325
Wood, J.D., see Xia, Y. (206) 231
Strohmann, C., see Waelbroeck, M. (206) 95
Strosberg, A.D., see Couraud, P.-O. (206) 191
Stumpo, R.J., Pullan, L.M. and Salama, A.I.
Xia, Y., Baidan, L.V., Fertel, R.H. and Wood, J.D.
The inhibition of [!*°I]w-conotoxin GVIA binding to neuronal
Determination of levels of cyclic AMP in the myenteric plexus of
membranes by neomycin may be mediated by a GTP-binding
guinea-pig small intestine (206) 231
protein (206) 155
Sutherland, M.L., see Shingai, R. (206) 77
Yamamoto, H., Kanaide, H. and Nakamura, M.
Tacke, R., see Waelbroeck, M. (206) 95 Dextran sulfate inhibits the inositol 1,4,5-trisphosphate-induced
Tam, Y.-K., see Li, P.P. (206) 165 Ca*t release from skinned and cultured smooth muscle cells (206)
Tastenoy, M., see Waelbroeck, M. (206) 95 175
Torres-Marquez, M.E., Villalobos-Molina, R. and Garcia-Sainz, J.A. Yamamura, H.I., see Henderson, A.K. (206) 251
a,-Adrenoceptor subtypes in aorta (a,, ) and liver (a,,) (206) 199
Yorek, M.A., see Sheff, K.Y. (206) 105
Yoshida, H., see Kawamoto, H. (206) 33
Van Calker, D., Steber, R., Klotz, K.-N. and Greil, W. Young, L.T., see Li, P.P. (206) 165
Carbamazepine distinguishes between adenosine receptors that
Yui, Y., see Hiki, K. (206) 163
mediate different second messenger responses (206) 285
Van der Wenden, E.M., Van Galen, P.J.M., IJzerman, A.P. and
Soudijn, W. Zhou, G.-Z. and Musacchio, J.M.
Mapping the xanthine C8-region of the adenosine A, receptor Computer-assisted modeling of multiple dextromethorphan and
with computer graphics (206) 315 sigma binding sites in guinea pig brain (206) 261

European Journal of Pharmacology — Molecular Pharmacology Section, 206 (1991) 355-361
© 1991 Elsevier Science Publishers B.V. 0922-4106 /91 /$03.50
Key word index
Acetylcholine Adipose tissue
Choline; Hemicholinium-3; Neuroblastoma-glioma; Hybrid cells; Hypothyroidism; Insulin; Epinephrine; Phosphoinositides (Andersen,
Choline transport (Sheff, K.Y. (206) 105) P.H. (206) 81)
Acetylcholine release ADP ribosylation
w-Conotoxin GVIA; Ca** influx; Ca** (intracellular free); Voltage- Li*; GTP-binding protein (inhibitory); Islet-activating protein;
sensitive Ca**+ channels (Lundy, P.M. (206) 61) Cardiac ventricular cell (rat) (Kawamoto, H. (206) 33)
8-Adrenoceptors
Action potential
Guanine nucleotide-binding proteins; Noradrenaline; Cytokine
Adenosine A, receptor; Cytosolic Ca?*; Pituitary (Mollard, P. (206)
(Reithmann, C. (206) 53)
271)
In situ hybridization; Lung; Autoradiography (Hamid, Q.A. (206)
Acylating agents
133)
t-Butylbicyclophosphorothionate (TBPS); t-Butylbicycloorthobenzo-
ate (TBOB); Cl” uptake; Synaptoneurosomes; Muscimol (Moody,
Desipramine; Cyclic AMP; K;/Ky; C6 glioma (Manji, H.K. (206)
E.J. (206) 113)
159)
Adamantane
a,-Adrenoceptor subtypes
Glutamate; NMDA (N-Methyl-D-aspartate); MK-801; Memantine;
Liver cells; Aorta; 5-Methyl urapidil (Torres-Marquez, M.E. (206)
Amantadine; Parkinson’s disease (Kornhuber, J. (206) 297)
199)
Adenosine Affinity modulation
Adenosine A, receptor; FRTL-5 thyroid cells; Phosphoinositide (?H]Imipramine; [?H]Paroxetine; [*H]Citalopram; 5-Hydroxytrypta-
turnover; Arachidonate release; Purine P, receptor (Nazarea, M. (206) mine transport complex; Brain; (Human); (Rat) (Plenge, P. (206) 243)
47)
Alcohols
Adenosine A, receptor Protein kinase C; Diacylglycerol; Lipid fluidity; Anesthetics (Lester,
Adenosine; FRTL-5 thyroid cells; Phosphoinositide turnover; D.S. (206) 301)
Arachidonate release; Purine P, receptor (Nazarea, M. (206) 47)
Amantadine
Cytosolic Ca**; Action potential; Pituitary (Mollard, P. (206) 271) Glutamate; NMDA (N-Methyl-D-aspartate); MK-801; Adamantane;
Memantine; Parkinson’s disease (Kornhuber, J. (206) 297)
Adenosine A, receptor antagonists; Xanthine C8-region; Computer
cAMP
graphics (Van der Wenden, E.M. (206) 315)
Cardiac ventricle; Sinoatrial node; cGMP; cGMP-stimulated phos-
phodiesterase; Phosphodiesterase inhibitors (Komas, N. (206) 5)
Adenosine A, receptor antagonists
Adenosine A, receptor; Xanthine C8-region; Computer graphics
Enteric nervous system; Myenteric neurons; Intestine; Synaptic trans-
(Van der Wenden, E.M. (206) 315)
mission; Forskolin (Xia, Y. (206) 231)
Adenosine receptors
Amphiphilic peptides
Cyclic AMP; Inositol phosphates; Astroglia; GH,-cells; Neutrophils
Mastoparan; Phospholipase C; G proteins (Gusovsky, F. (206) 309)
(human) (Van Calker, D. (206) 285)
Analgesics
Adenosine A, receptors Receptors; Morphine; Narcotics; Molecular model; Quantum theory;
Fat cell (human); Adipocytes; Guanine nucleotides; Lipolysis; (Addictive); (Chemistry); (Pharmaceuticals) (Goldblum, A. (206) 119)
[7H]DPCPX (P H]1,3-dipropyl-8-cyclopentylxanthine); [7H](—)-PIA
(? H\(-)-N®-phenylisopropyladenosine) (Larrouy, D. (206) 139)
Anesthetics
Protein kinase C; Diacylglycerol; Lipid fluidity; Alcohols (Lester,
Adipocytes D.S. (206) 301)
Adenosine A, receptors; Fat cell (human); Guanine nucleotides;
Lipolysis; [*H]DPCPX (( H]1,3-dipropyl-8-cyclopentylxanthine); Angiotensin-converting enzyme
(7H\(—)-PIA ((°H\(—)-N°-phenylisopropyladenosine) (Larrouy, D. Renal brush-border membranes; Ramiprilat binding; Cl” (Grima, M.
(206) 139) (206) 203)
356
Angiotensin II receptors t-Butylbicyclophosphorothionate (TBPS)
Lung; Angiotensin II receptor subtypes; (Rat) (Entzeroth, M. (206) Acylating agents; t-Butylbicycloorthobenzoate (TBOB); Cl” uptake;
237) Synaptoneurosomes; Muscimol (Moody, E.J. (206) 113)
Angiotensin II receptor subtypes Ca**
Angiotensin II receptors; Lung; (Rat) (Entzeroth, M. (206) 237) Macrophages; Arachidonic acid; Leukotriene B,; Prostacyclin; Fura2
(Letari, O. (206) 211)
Aorta
a,-Adrenoceptor subtypes; Liver cells; 5-Methyl urapidil (Torres- Smooth muscle (vascular); DNA; Proliferation; A7r, cells (Sperti, G.
Marquez, M.E. (206) 199) (206) 279)
Arachidonate release Ca** channel antagonists
Adenosine; Adenosine A, receptor; FRTL-5 thyroid cells; Phos- [?H]nitrendipine; [*H]d-cis-diltiazem; Calmodulin antagonists; Cyclic
phoinositide turnover; Purine P, receptor (Nazarea, M. (206) 47) nucleotide phosphodiesterase (Schaeffer, P. (206) 325)
Arachidonic acid Ca** influx
Macrophages; Ca?*; Leukotriene B,; Prostacyclin; Fura2 (Letari, O. w-Conotoxin GVIA; Acetylcholine release; Ca** (intracellular free);
(206) 211) Voltage-sensitive Ca** channels (Lundy, P.M. (206) 61)
Ajrs cells Ca** (intracellular free)
Smooth muscle (vascular); Ca*+: DNA; Proliferation (Sperti, G. w-Conotoxin GVIA; Acetylcholine release; Ca 2+ influx; Voltage-sen-
(206) 279) sitive Ca** channels (Lundy, P.M. (206) 61)
Astrocytes Ca** (intraneuronal) and Na* (intraneuronal)
Norepinephrine; Cyclic GMP; Nitric oxide (NO) (Agulldé, L. (206) 3,4-Diaminopyridine; Noradrenaline release; Phorbol ester; Protein
343) kinase C; Hippocampus (Huang, H.Y. (206) 221)
Astrocytoma C6 (rat) Calmodulin antagonists
Endothelin receptors (Couraud, P.-O. (206) 191) [*H]nitrendipine; [*H]d-cis-diltiazem; Cyclic nucleotide phos-
phodiesterase; Ca?* channel antagonists (Schaeffer, P. (206) 325)
Astroglia
Adenosine receptors; Cyclic AMP; Inositol phosphates; GH,-cells; Ca** mobilization
Neutrophils (human) (Van Calker, D. (206) 285) Fluo-3, AM; Neurokinin A (NKA); NK, receptor; Transfected
fibroblast (Henderson, A.K. (206) 251)
Atrial natriuretic factor (ANF)
Guanylate cyclase; Oxidation-reduction; cGMP; Thiol (Fille, H.-J. Carbachol
(206) 69) Iris sphincter (bovine); M&B 22948; Inositol trisphosphate; Contrac-
tion; Smooth muscle (Akhtar, R.A. (206) 291)
Autoradiography
B-Adrenoceptors; In situ hybridization; Lung (Hamid, Q.A. (206) Cardiac ventricle
133) Sinoatrial node; cAMP; cGMP; cGMP-stimulated phosphodiesterase;
Phosphodiesterase inhibitors (Komas, N. (206) 5)
Basal ganglia
MDMA (3,4-methylenedioxymethamphetamine); Dopamine; c-Fos Cardiac ventricular cell (rat)
protein; (Rat) (Dragunow, M. (206) 255) Li*; GTP-binding protein (inhibitory); ADP ribosylation; Islet-
activating protein (Kawamoto, H. (206) 33)
Basolateral membranes
(>H]Idazoxan; [*H]Rauwolscine; Kidney (human) (Lachaud-Pettiti, Ca** release
V. (206) 23) Dextran sulfate; Inositol 1,4,5-triphosphate; Smooth muscle cells
(Yamamoto, H. (206) 175)
Binding site (accessory)
Histamine H, receptor; Histamine H, receptor antagonists (Orsetti, Cerebellar granule cells
M. (206) 167) Muscarinic M, receptors; Phosphoinositide metabolism; Inositol
1,4,5-trisphosphate (Whitham, E.M. (206) 181)
I-BOP
TXA,/PGH, receptors; I-PTA-OH; Dihydropyridines; Platelets (hu- C6 glioma
man) (Mayeux, P.R. (206) 15) Desipramine; £-Adrenoceptors; Cyclic AMP; K; /Ky (Manji, H.K.
(206) 159)
Brain
[?H]Imipramine; (?H]Paroxetine; [*H]Citalopram; 5-Hydroxytrypta- Choline
mine transport complex; Affinity modulation; (Human); (Rat) Acetylcholine; Hemicholinium-3; Neuroblastoma-glioma; Hybrid
(Plenge, P. (206) 243) cells; Choline transport (Sheff, K.Y. (206) 105)
t-Butylbicycloorthobenzoate (TBOB) Choline transport
t-Butylbicyclophosphorothionate (TBPS); Acylating agents; Cl™ up- Choline; Acetylcholine; Hemicholinium-3; Neuroblastoma-glioma;
take; Synaptoneurosomes; Muscimol (Moody, E.J. (206) 113) Hybrid cells (Sheff, K.Y. (206) 105)
{>H]Citalopram Dextromethorphan
[*H]Imipramine; [*H]Paroxetine; 5-Hydroxytryptamine transport Haloperidol; (+ )-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine; 1,3-
complex; Affinity modulation; Brain; (Human); (Rat) (Plenge, P. Di-o-tolyl guanidine; o receptor; Computer-assisted modeling (Zhou,
(206) 243) G.-Z. (206) 261)
Ci~ Diacylglycerol
Angiotensin-converting enzyme; Renal brush-border membranes; Protein kinase C; Lipid fluidity; Alcohols; Anesthetics (Lester, D.S.
Ramiprilat binding (Grima, M. (206) 203) (206) 301)
Cloned subtypes 3,4-Diaminopyridine
Neurosteroid; GABA, receptors; Electrophysiology (Shingai, R. (206) Noradrenaline release; Phorbol ester; Protein kinase C; Ca** (in-
77) traneuronal) and Na® (intraneuronal); Hippocampus (Huang, H.Y.
(206) 221)
Cl” uptake
t-Butylbicyclophosphorothionate (TBPS); Acylating agents; t- 5,7-Dichloroquinoline-2-carboxylic acid (5,7-DCKA)
Butylbicycloorthobenzoate (TBOB); Synaptoneurosomes; Muscimol Glutamate; Glycine; (Antagonist); (Rat) (Baron, B.M. (206) 149)
(Moody, E.J. (206) 113)
Dihydropyridines
Computer-assisted modeling TXA,/PGH, receptors; I-PTA-OH; I-BOP; Platelets (human)
Dextromethorphan; Haloperidol; (+ )-3-(3-hydroxyphenyl)-N-(1-pro-
(Mayeux, P.R. (206) 15)
pyl)piperidine; 1,3-Di-o-tolyl guanidine; o receptor (Zhou, G.-Z. (206)
261) |* H]d-cis-diltiazem
[?H]nitrendipine; Calmodulin antagonists; Cyclic nucleotide phos-
Computer graphics
phodiesterase; Ca?* channel antagonists (Schaeffer, P. (206) 325)
Adenosine A, receptor; Adenosine A, receptor antagonists; Xanthine
C8-region (Van der Wenden, E.M. (206) 315)
1,3-Di-o-tolyl guanidine
Dextromethorphan; Haloperidol; (+ )-3-(3-hydroxyphenyl)-N-(1-pro-
w-Conotoxin GVIA
pyl)piperidine; o receptor; Computer-assisted modeling (Zhou, G.-Z.
Acetylcholine release; Ca** influx; Ca** (intracellular free);
(206) 261)
Voltage-sensitive Ca** channels (Lundy, P.M. (206) 61)
[SH|DPCPX (PHI 1,3-dipropyl-8-cyclopentylxanthine)
Neomycin; GTP; N-channel (Stumpo, R.J. (206) 155)
Adenosine A, receptors; Fat cell (human); Adipocytes; Guanine
nucleotides; Lipolysis; {*H](—)-PIA (P H\(-)-N®-phenylisopropyla-
Contraction
denosine) (Larrouy, D. (206) 139)
Iris sphincter (bovine); Carbachol; M&B 22948; Inositol tris-
phosphate; Smooth muscle (Akhtar, R.A. (206) 291)
Divalent cations
[?H]Leukotriene B,; Leukotriene B,; Leukotriene receptors; Guanine
Cyclic AMP
nucleotides; (Guanyl-5’-yl-imidodiphosphate) GppNHp (Falcone,
Desipramine; B-Adrenoceptors; K;/K,; C6 glioma (Manji, H.K.
R.C. (206) 333)
(206) 159)
DNA
Adenosine receptors; Inositol phosphates; Astroglia; GH,-cells; Neu-
Smooth muscle (vascular); Ca**; Proliferation; A7r, cells (Sperti, G.
trophils (human) (Van Calker, D. (206) 285)
(206) 279)
Cyclic GMP
Dopamine
Neurotensin receptors; Ontogeny (Cusack, B. (206) 339)
MDMA (3,4-methylenedioxymethamphetamine); c-Fos protein; Basal
ganglia; (Rat) (Dragunow, M. (206) 255)
Norepinephrine; Astrocytes; Nitric oxide (NO) (Agulld, L. (206) 343)
Electrophysiology
Cyclic nucleotide phosphodiesterase
(?H]nitrendipine; [?H]d-cis-diltiazem; Calmodulin antagonists; Ca** Neurosteroid; GABA, receptors; Cloned subtypes (Shingai, R. (206)
77)
channel antagonists (Schaeffer, P. (206) 325)
Cytokine Endothelin receptors
Guanine nucleotide-binding proteins; B-Adrenoceptors; Noradrena- Astrocytoma C6 (rat) (Couraud, P.-O. (206) 191)
line (Reithmann, C. (206) 53)
Enteric nervous system
Cytosolic Ca”* cAMP; Myenteric neurons; Intestine; Synaptic transmission; For-
Adenosine A, receptor; Action potential; Pituitary (Mollard, P. (206) skolin (Xia, Y. (206) 231)
271)
Epinephrine
Desipramine Adipose tissue; Hypothyroidism; Insulin; Phosphoinositides (Ander-
B-Adrenoceptors; Cyclic AMP; K,;/Ky,; C6 glioma (Manji, H.K. sen, P.H. (206) 81)
(206) 159)
Fat cell (human)
Dextran sulfate Adenosine A, receptors; Adipocytes; Guanine nucleotides; Lipolysis;
(SH]DPCPX ({°H]1,3-dipropyl-8-cyclopentylxanthine); [*H](—)-PIA
Inositol 1,4,5-triphosphate; Smooth muscle cells; Ca** release
(Yamamoto, H. (206) 175) (H\(-)-N®-phenylisopropyladenosine) (Larrouy, D. (206) 139)
358
Fluo-3, AM GTP-binding protein (inhibitory)
Ca?* mobilization; Neurokinin A (NKA); NK, receptor; Trans- Li*; ADP ribosylation; Islet-activating protein; Cardiac ventricular
fected fibroblast (Henderson, A.K. (206) 251) cell (rat) (Kawamoto, H. (206) 33)
p-Fluoro-hexahydro-sila-difenidol Guanine nucleotide-binding proteins
Muscarinic receptor subtypes (M,, M>, M3, and (putative) M4); B-Adrenoceptors; Noradrenaline; Cytokine (Reithmann, C. (206) 53)
Muscarinic receptor antagonists (selective); Hexahydro-sila-difenidol
analogues; Stereoselectivity (at muscarinic receptors) (Waelbroeck, M. Guanine nucleotides
(206) 95) Adenosine A, receptors; Fat cell (human); Adipocytes; Ii polysis;
[7H]DPCPX ((°H]1,3-dipropyl-8-cyclopentylxanthine); [7H](—)-PIA
Forskolin (P H\(—)-N°-phenylisopropyladenosine) (Larrouy, D. (206) 139)
cAMP; Enteric nervous system; Myenteric neurons; Intestine; Syn-
aptic transmission (Xia, Y. (206) 231) [*H]Leukotriene B,; Leukotriene B,; Leukotriene receptors; (Guanyl-
5’-yl-imidodiphosphate) GppNHp; Divalent cations (Falcone, R.C.
(206) 333)
c-Fos protein
MDMA (3,4-methylenedioxymethamphetamine); Dopamine; Basal
ganglia; (Rat) (Dragunow, M. (206) 255) Guanylate cyclase
Oxidation-reduction; Atrial natriuretic factor (ANF); cGMP; Thiol
(Fiille, H.-J. (206) 69)
FRTL-5 thyroid cells
Adenosine; Adenosine A, receptor; Phosphoinositide turnover;
Arachidonate release; Purine P, receptor (Nazarea, M. (206) 47) Haloperidol
Dextromethorphan; (+ )-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine;
1,3-Di-o-tolyl guanidine; o receptor; Computer-assisted modeling
Fura2
(Zhou, G.-Z. (206) 261)
Macrophages; Ca**t:; Arachidonic acid; Leukotriene B,; Prostacyclin
(Letari, O. (206) 211)
Hemicholinium-3
Choline; Acetylcholine; Neuroblastoma-glioma; Hybrid cells; Choline
GABA , receptors
transport (Sheff, K.Y. (206) 105)
Neurosteroid; Cloned subtypes; Electrophysiology (Shingai, R. (206)
77)
Hexahydro-sila-difenidol analogues
Muscarinic receptor subtypes (M,, M>, M3, and (putative) M,);
GH,-cells
Muscarinic receptor antagonists (selective); p-Fluoro-hexahydro-sila-
Adenosine receptors; Cyclic AMP; Inositol phosphates; Astroglia;
difenidol; Stereoselectivity (at muscarinic receptors) (Waelbroeck, M.
Neutrophils (human) (Van Calker, D. (206) 285)
(206) 95)
Glutamate
Hippocampus
Glycine; 5,7-Dichloroquinoline-2-carboxylic acid (5,7-DCKA);
3,4-Diaminopyridine; Noradrenaline release; Phorbol ester; Protein
(Antagonist); (Rat) (Baron, B.M. (206) 149)
kinase C; Ca** (intraneuronal) and Na‘ (intraneuronal) (Huang,
H.Y. (206) 221)
NMDA (N-Methyl-D-aspartate); MK-801; Adamantane; Memantine;
Amantadine; Parkinson’s disease (Kornhuber, J. (206) 297)
Histamine H_, receptor
Histamine H, receptor antagonists; Binding site (accessory) (Orsetti,
Glycine
M. (206) 167)
Glutamate; 5,7-Dichloroquinoline-2-carboxylic acid (5,7-DCKA);
(Antagonist); (Rat) (Baron, B.M. (206) 149)
Histamine H, receptor antagonists
Histamine H, receptor; Binding site (accessory) (Orsetti, M. (206)
cGMP
167)
Cardiac ventricle; Sinoatrial node; cAMP; cGMP-stimulated phos-
phodiesterase; Phosphodiesterase inhibitors (Komas, N. (206) 5)
5-HT release
[?H]Ketanserin binding; Platelets (human); Non-serotonergic binding
Guanylate cyclase; Oxidation-reduction; Atrial natriuretic factor sites (Leysen, J.E. (206) 39)
(ANF); Thiol (Fiille, H.-J. (206) 69)
Hybrid cells
cGMP-stimulated phosphodiesterase Choline; Acetylcholine; Hemicholinium-3; Neuroblastoma-glioma;
Cardiac ventricle; Sinoatrial node; cAMP; cGMP; Phosphodiesterase Choline transport (Sheff, K.Y. (206) 105)
inhibitors (Komas, N. (206) 5)
(+ )-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine
(Guanyl-5’-yl-imidodiphosphate) GppNHp Dextromethorphan; Haloperidol; 1,3-Di-o-tolyl guanidine; o recep-
[?H]Leukotriene B,; Leukotriene B,; Leukotriene receptors; Guanine tor; Computer-assisted modeling (Zhou, G.-Z. (206) 261)
nucleotides; Divalent cations (Falcone, R.C. (206) 333)
5-Hydroxytryptamine transport complex
G proteins [*H]Imipramine; [(*H]Paroxetine; [?H]Citalopram; Affinity modula-
Mastoparan; Phospholipase C; Amphiphilic peptides (Gusovsky, F. tion; Brain; (Human); (Rat) (Plenge, P. (206) 243)
(206) 309)
Hypothyroidism
GTP Adipose tissue; Insulin; Epinephrine; Phosphoinositides (Andersen,
w-Conotoxin GVIA; Neomycin; N-channel (Stumpo, R.J. (206) 155) P.H. (206) 81)
|*H]Leukotriene B,
|* H]Idazoxan
[?H]Rauwolscine; Kidney (human); Basolateral membranes (La- Leukotriene B,; Leukotriene receptors; Guanine nucleotides;
chaud-Pettiti, V. (206) 23) (Guanyl-5’-yl-imidodiphosphate) GppNHp; Divalent cations (Fal-
cone, R.C. (206) 333)
k H]Imipramine
[7H]Paroxetine; [*H]Citalopram; 5-Hydroxytryptamine transport Leukotriene receptors
complex; Affinity modulation; Brain; (Human); (Rat) (Plenge, P. [?H]Leukotriene B,; Leukotriene B,; Guanine nucleotides; (Guanyl-
(206) 243) 5’-yl-imidodiphosphate) GppNHp; Divalent cations (Falcone, R.C.
(206) 333)
Inositol phosphate formation (direct and indirect)
Muscarinic receptors; Striatal neurons in primary culture; Ontogeny 2
(Schmidt, B.H. (206) 87) GTP-binding protein (inhibitory); ADP ribosylation; Islet-activating
protein; Cardiac ventricular cell (rat) (Kawamoto, H. (206) 33)
Inositol phosphates
Adenosine receptors; Cyclic AMP; Astroglia; GH-cells; Neutrophils Lipid fluidity
(human) (Van Calker, D. (206) 285) Protein kinase C; Diacylglycerol; Alcohols; Anesthetics (Lester, D.S.
(206) 301)
Inositol 1,4,5-triphosphate
Dextran sulfate; Smooth muscle cells; Ca** release (Yamamoto, H. Lipolysis
(206) 175) Adenosine A, receptors; Fat cell (human); Adipocytes; Guanine
nucleotides; [*H]DPCPX ((° H]1,3-dipropyl-8-cyclopentylxanthine);
Inositol trisphosphate [7H\(—)-PIA ( H\(_)-N°-phenylisopropyladenosine) (Larrouy, D.
Iris sphincter (bovine); Carbachol; M& B 22948; Contraction; Smooth (206) 139)
muscle (Akhtar, R.A. (206) 291)
Liver cells
Inositol 1,4,5-trisphosphate
a,-Adrenoceptor subtypes; Aorta; 5-Methyl urapidil (Torres-Marquez,
Cerebellar granule cells; Muscarinic M, receptors; Phosphoinositide
M.E. (206) 199)
metabolism (Whitham, E.M. (206) 181)
Lung
In situ hybridization
B-Adrenoceptors; In situ hybridization; Autoradiography (Hamid,
B-Adrenoceptors; Lung; Autoradiography (Hamid, Q.A. (206) 133)
Q.A. (206) 133)
Insulin
Angiotensin II receptors; Angiotensin II receptor subtypes; (Rat)
Adipose tissue; Hypothyroidism; Epinephrine; Phosphoinositides
(Entzeroth, M. (206) 237)
(Andersen, P.H. (206) 81)
Macrophages
Intestine
Ca?*: Arachidonic acid; Leukotriene B,; Prostacyclin; Fura2 (Letari,
cAMP; Enteric nervous system; Myenteric neurons; Synaptic trans-
O. (206) 211)
mission; Forskolin (Xia, Y. (206) 231)
Mastoparan
Iris sphincter (bovine)
Phospholipase C; G proteins; Amphiphilic peptides (Gusovsky, F.
Carbachol; M & B 22948; Inositol trisphosphate; Contraction; Smooth
(206) 309)
muscle (Akhtar, R.A. (206) 291)
M&B 22948
Islet-activating protein
Li*; GTP-binding protein (inhibitory); ADP ribosylation; Cardiac Iris sphincter (bovine); Carbachol; Inositol trisphosphate; Contrac-
tion; Smooth muscle (Akhtar, R.A. (206) 291)
ventricular cell (rat) (Kawamoto, H. (206) 33)
MDMA (3,4-methylenedioxymethamphetamine)
{>H]Ketanserin binding
Dopamine; c-Fos protein; Basal ganglia; (Rat) (Dragunow, M. (206)
Platelets (human); Non-serotonergic binding sites; 5-HT release (Ley-
255)
sen, J.E. (206) 39)
Kidney (human) Memantine
[7H]Idazoxan; [*H]Rauwolscine; Basolateral membranes (Lachaud- Glutamate; NMDA (N-Methyl-D-aspartate); MK-801; Adamantane;
Amantadine; Parkinson’s disease (Kornhuber, J. (206) 297)
Pettiti, V. (206) 23)
K, /Ky 5-Methy! urapidil
a,-Adrenoceptor subtypes; Liver cells; Aorta (Torres-Marquez, M.E.
Desipramine; $-Adrenoceptors; Cyclic AMP; C6 glioma (Manji, H.K.
(206) 159) (206) 199)
Leukotriene B, MK-801
Macrophages; Ca?*; Arachidonic acid; Prostacyclin; Fura2 (Letari, Glutamate; NMDA (N-Methyl-pD-aspartate); Adamantane; Meman-
O. (206) 211) tine; Amantadine; Parkinson’s disease (Kornhuber, J. (206) 297)
[?H]Leukotriene B,; Leukotriene receptors; Guanine nucleotides; Molecular model
(Guanyl-5’-yl-imidodiphosphate) GppNHp; Divalent cations (Fal- Receptors; Morphine; Analgesics; Narcotics; Quantum theory; (Ad-
cone, R.C. (206) 333) dictive); (Chemistry); (Pharmaceuticals) (Goldblum, A. (206) 119)
360
Morphine Nitric oxide (NO)
Receptors; Analgesics; Narcotics; Molecular model; Quantum theory; Norepinephrine; Cyclic GMP; Astrocytes (Agullé, L. (206) 343)
(Addictive); (Chemistry); (Pharmaceuticals) (Goldblum, A. (206) 119)
NK, receptor
Muscarinic receptor antagonists (selective) Ca?* mobilization; Fluo-3, AM; Neurokinin A (NKA); Transfected
Muscarinic receptor subtypes (M,, M,, M3, and (putative) M,); fibroblast (Henderson, A.K. (206) 251)
Hexahydro-sila-difenidol analogues; p-Fluoro-hexahydro-sila-difen-
idol; Stereoselectivity (at muscarinic receptors) (Waelbroeck, M. (206) NMDA (N-Methyl-D-aspartate)
95) Glutamate; MK-801; Adamantane; Memantine; Amantadine;
Parkinson’s disease (Kornhuber, J. (206) 297)
Muscarinic receptors
Inositol phosphate formation (direct and indirect); Striatal neurons in Non-serotonergic binding sites
[°H]Ketanserin binding; Platelets (human); 5-HT release (Leysen, J.E.
primary culture; Ontogeny (Schmidt, B.H. (206) 87)
(206) 39)
Muscarinic M, receptors
Noradrenaline
Cerebellar granule cells; Phosphoinositide metabolism; Inositol 1,4,5-
Guanine nucleotide-binding proteins; f$-Adrenoceptors; Cytokine
trisphosphate (Whitham, E.M. (206) 181)
(Reithmann, C. (206) 53)
Muscarinic receptor subtypes (M,, M,, M3, and (putative) M ,)
Noradrenaline release
Muscarinic receptor antagonists (selective); Hexahydro-sila-difenidol
3,4-Diaminopyridine; Phorbol ester; Protein kinase C; ir (in-
analogues; p-Fluoro-hexahydro-sila-difenidol; Stereoselectivity (at
traneuronal) and Na* (intraneuronal); Hippocampus (Huang, H.Y.
muscarinic receptors) (Waelbroeck, M. (206) 95)
(206) 221)
Muscimol
Norepinephrine
t-Butylbicyclophosphorothionate (TBPS); Acylating agents; t-
Cyclic GMP; Astrocytes; Nitric oxide (NO) (Agulldé, L. (206) 343)
Butylbicycloorthobenzoate (TBOB); Cl” uptake; Synaptoneurosomes
(Moody, E.J. (206) 113)
Ontogeny
Muscarinic receptors; Inositol phosphate formation (direct and indi-
Myenteric neurons rect); Striatal neurons in primary culture (Schmidt, B.H. (206) 87)
cAMP; Enteric nervous system; Intestine; Synaptic transmission;
Forskolin (Xia, Y. (206) 231) Neurotensin receptors; Cyclic GMP (Cusack, B. (206) 339)
Narcotics Oxidation-reduction
Receptors; Morphine; Analgesics; Molecular model; Quantum the- Guanylate cyclase; Atrial natriuretic factor (ANF); cGMP; Thiol
ory; (Addictive); (Chemistry); (Pharmaceuticals) (Goldblum, A. (206) (Fille, H.-J. (206) 69)
119)
Parkinson’s disease
N-channel Glutamate; NMDA (N-Methyl-D-aspartate); MK-801; Adamantane;
w-Conotoxin GVIA; Neomycin; GTP (Stumpo, R.J. (206) 155) Memantine; Amantadine (Kornhuber, J. (206) 297)
[>H]Paroxetine
Neomycin
w-Conotoxin GVIA; GTP; N-channel (Stumpo, R.J. (206) 155) [?H]imipramine; [7H]Citalopram; 5-Hydroxytryptamine transport
complex; Affinity modulation; Brain; (Human); (Rat) (Plenge, P.
(206) 243)
Neuroblastoma-glioma
Choline; Acetylcholine; Hemicholinium-3; Hybrid cells; Choline
[°H](—)-PIA ((/H\(-)-N®-phenylisopropyladenosine)
transport (Sheff, K.Y. (206) 105)
Adenosine A, receptors; Fat cell (human); Adipocytes; Guanine
nucleotides; Lipolysis; [*>H]DPCPX (PH]1,3-dipropyl-8-cyclopentyl-
Neurokinin A (NKA)
xanthine) (Larrouy, D. (206) 139)
Ca?*+ mobilization; Fluo-3, AM; NK, receptor; Transfected fibro-
blast (Henderson, A.K. (206) 251)
Phorbol ester
3,4-Diaminopyridine; Noradrenaline release; Protein kinase C; Ca?t
Neurosteroid
(intraneuronal) and Na* (intraneuronal); Hippocampus (Huang, H.Y.
GABA, receptors; Cloned subtypes; Electrophysiology (Shingai, R&.
(206) 221)
(206) 77)
Phosphodiesterase inhibitors
Neurotensin receptors
Cardiac ventricle; Sinoatrial node; cAMP; cGMP; cGMP-stimulated
Cyclic GMP; Ontogeny (Cusack, B. (206) 339)
phosphodiesterase (Komas, N. (206) 5)
Neutrophils (human) Phosphoinositide metabolism
Adenosine receptors; Cyclic AMP; Inositol phosphates; Astroglia; Cerebellar granule cells; Muscarinic M, receptors; Inositol 1,4,5-
GH.,-cells (Van Calker, D. (206) 285) trisphosphate (Whitham, E.M. (206) 181)
[>H]nitrendipine Phosphoinositides
[?H]d-cis-diltiazem; Calmodulin antagonists; Cyclic nucleotide phos- Adipose tissue; Hypothyroidism; Insulin; Epinephrine (Andersen,
phodiesterase; Ca?* channel antagonists (Schaeffer, P. (206) 325) P.H. (206) 81)