Table Of Content

European Journal of Pharmacology, 203 (1991) 425-428 © 1991 Elsevier Science Publishers B.V. All rights reserved 0014-2999 /91 $03.50 Author index Adachi, H., see Kawamura, T. (203) 399 Chugh, Y., Saha, N., Sankaranarayanan, A. and Sharma, P.L Ahrén, B., see Gregersen, S. (203) 111 Memory enhancing effects of granisetron (BRL 43694) in a Alabadi, J.A., see Salom, J.B. (203) 33 passive avoidance task (203) 121 Alborch, E., see Salom, J.B. (203) 33 Conforti, L., see Tohse, N. (203) 307 Alper, R.H., see Pérgola, P.E. (203) 145 Costa, G., see Garcia-Pascual, A. (203) 259 Altura, B.M., see Zhang, A. (203) 223 Costentin, J., see Bousselmame, R. (203) 295 Altura, B.T., see Zhang, A. (203) 223 Cowan, A., see Liu-Chen, L.-Y. (203) 195 Alvarez, C., see Salom, J.B. (203) 33 Coy, D.H., see Zacharia, S. (203) 353 Amir, S. and English, A.M. Cridland, R.A., Sutak, M. and Jhamandas, K. An inhibitor of nitric oxide production, N“-nitro-L-arginine- Characteristics of precipitated withdrawal from spinal morphine methyl ester, improves survival in anaphylactic shock (203) 125 changes in [Met*]Jenkephalin levels (203) 93 BackhauB, C., see Prehn, J.H.M. (203) 213 Dabiré, H., Bajjou, R., Chaouche-Teyara, K., Fournier, B., Bajjou, R., see Dabiré, H. (203) 323 De Nanteuil, G., Laubie, M., Safar, M. and Schmitt, H. Bang Olsen, U. and Lund, A. $14063: a new potent 5-HT,, receptor antagonist devoid of Inhibition by glutamate antagonists, MK-801 and NBOX, of B-adrenoceptor blocking properties (203) 323 cutaneo-cardiovascular pain reflex in rats (203) 133 DeHaven-Hudkins, D.L., Hildebrand, L.M., Fleissner, L.C. and Bao, J.-X., Gonon, F. and Stjarne, L Ward, SJ Electrochemical and electrophysiological analysis of the effects of Lack of correlation between o binding potency and inhibition of SK&F 104078 on prejunctional a,-adrenoceptors (203) 159 contractions in the mouse vas deferens preparation (203) 329 Barbanti, G., see Giuliani, S. (203) 365 De Jongste, J., see Jongejan, R. (203) 187 Barr, A.J., Watson, S.P., Bernal, A.L. and Nimmo, A.J. Delay-Goyet, P. and Lundberg, J.M. The presence of NK , tachykinin receptors on rat uterus (203) 287 Cigarette smoke-induced airway oedema is blocked by the NK, Bartfai, T., see Gregersen, S. (203) 111 antagonist, CP-96,345 (203) 157 Bataille, D., see Carles-Bonnet, C. (203) 245 Della Bella, D., see Sala, R. (203) 17 Bernal, A.L., see Barr, A.J. (203) 287 Demiryurek, A.T., Wadsworth, R.M. and Kane, K.A Bielen, F.V., see Verdonck, F. (203) 371 Pharmacological evidence for the role of mediators in hypoxia-in- Bitran, M., Torres, G., Fournier, A., St Pierre, S. and Huidobro-Toro, duced vasoconstriction in sheep isolated intrapulmonary artery J.P rings (203) 1 Age and castration modulate the inhibitory action of neuropep- De Montis, G., see Devoto, P. (203) 67 tide Y on neurotransmission in the rat vas deferens (203) 267 De Nanteuil, G., see Dabiré, H. (203) 323 Black, C.K., see Schmidt, C.J. (203) 41 Desaulles, E., Boux, O. and Feltz, P. Boje, K., see Trullas, R. (203) 379 Caffeine-induced Ca?* release inhibits GABA, responsiveness Bonta, I., see Jongejan, R. (203) 187 in rat identified native primary afferents (203) 137 Borsini, F., Cesana, R., Vidi, A. and Mennini, T. De Souza, E.B., see Sharpe, L.G. (203) 141 Evidence that imipramine activates 5-HT,. receptor function Devoto, P., Pani, L.. Kuzmin, A. and De Montis, G. (203) 359 Inhibition of [>H]dopamine uptake by flunarizine (203) 67 Bourguignon, J.-J., see Schmidt, C. (203) 393 Donetti, A., see Turconi, M. (203) 203 Bousselmame, R., Michael-Titus, A. and Costentin, J. Dorje, F., Rettenmayr, N.M., Mutschler, E. and Lambrecht, G Desensitization of 4-opioid receptors does not modify the anal- Effect of extracellular calcium concentration on potency of mus- gesia induced by an enkephalinase inhibitor (203) 295 carinic agonists at M, and M, receptors in rabbit vas deferens Boux, O., see Desaulles, E. (203) 137 (203) 417 Bruning, J.W., see Van Furth, W.R. (203) 413 Duff, HJ., see Hill, R.J. (203) 51 Campbell, H.E., see Kiefer-Day, J.S. (203) 421 El-Fakahany, E.E., see Kiefer-Day, J.S. (203) 421 Canton, H., see Millan, M.J. (203) 319 Endo, T., see Ninomiya, H. (203) 299 Carella, A., see Zhang, A. (203) 223 English, A.M., see Amir, S. (203) 125 Carenzi, A., see Sala, R. (203) 17 Ertan, A., see Zacharia, S. (203) 353 Carles-Bonnet, C., Jarrousse, C., Niel, H., Martinez, J. and Bataille, Ertl, G., see Tian, R. (203) 71 D Oxyntomodulin and its (19-37) and (30-37) fragments inhibit Feltz, P., see Desaulles, E. (203) 137 histamine-stimulated gastric acid secretion in the conscious rat Fisone, G., see Gregersen, S. (203) 111 (203) 245 Fleissner, L.C., see DeHaven-Hudkins, D.L. (203) 329 Cesana, R., see Borsini, F. (203) 359 Folio, T., see Trullas, R. (203) 379 Cesana, R., see Turconi, M. (203) 203 Forn, J., see Marmol, F. (203) 181 Chaouche-Teyara, K., see Dabiré, H. (203) 323 Fournier, A., see Bitran, M. (203) 267 426 Fournier, B., see Dabiré, H. (203) 323 Jarrousse, C., see Carles-Bonnet, C. (203) 245 Frambes, N.A., see Spear, L.P. (203) 9 Jhamandas, K., see Cridland, R.A. (203) 93 Fukuda, H., see Ono, H. (203) 283 Jiang, N.-Y., see Zacharia, S. (203) 353 Fukuda, N., see Hashimoto, T. (203) 25 Jino, H., see Shibata, S. (203) 337 Fukushima, R., see Yoshida, Y. (203) 173 Jones, D.J., see Shibata, S. (203) 337 Jongejan, R., De Jongste, J., Raatgeep, R., Stijnen, T., Bonta, |. and Kerrebijn, K Galagan, M.E., Mordvintcev, P.I. and Vanin, A.F Effect of epithelial denudation, inflammatory mediators and mast Effect of riboflavin on hypotensive activity of dinitrosyl iron cell activation on the sensitivity of isolated human airways to complex with thiosulphate (203) 325 methacholine (203) 187 Gandhi, V., see Shibata, S. (203) 337 Garcia-Pascual, A., Costa, G., Isla, M. and Garcia-Sacristan, A Characterization of a-adrenoceptors in the preprostatic urethra of sexually immature male lambs (203) 259 Kamei, J., Mori, T., Igarashi, H. and Kasuya, Y Garcia-Sacristan, A., see Garcia-Pascual, A. (203) 259 Effects of 8-hydroxy-2-(di-n-propylamino)tetralin, a selective ago- Giachetti, A., see Giuliani, S. (203) 365 nist of 5-HT,, receptors, on the cough reflex in rats (203) 253 Giuliani, S., Barbanti, G., Turini, D., Quartara, L., Rovero, P., Kamei, J., Tanihara, H. and Kasuya, Y Giachetti, A. and Maggi, C.A Modulation of yu-mediated antitussive activity in rats by a 6 NK, tachykinin receptors and contraction of circular muscle of agonist (203) 153 the human colon: characterization of the NK, receptor subtype Kameyama, M., see Ninomiya, H. (203) 299 (203) 365 Kane, K.A., see Demiryurek, A.T. (203) 1 Gobaille, S., see Schmidt, C. (203) 393 Karkoutly, C., see Prehn, J.H.M. (203) 213 Gonon, F., see Bao, J.-X. (203) 159 Kasuya, Y., see Kamei, J. (203) 153 Goodwin, G., see Spear, L.P. (203) 9 Kasuya, Y., see Kamei, J. (203) 253 Gregersen, S., Hermansen, K., Langel, U , Fisone, G., Bartfai, T Kawamura, T., Adachi, H. and Ogawa, T and Ahrén, B. Cardiovascular effects of E4080, a novel bradycardiac agent with Galanin-induced inhibition of insulin secretion from rat islets coronary vasodilating properties, in anesthetized dogs (203) 399 effects of rat and pig galanin and galanin fragments and ana- Kerrebijn, K., see Jongejan, R. (203) 187 logues (203) 111 Kiefer-Day, J.S., Campbell, H.E., Towles, J. and El-Fakahany, E.E Gunn, L.K. and Piper, P.J Muscarinic subtype selectivity of tetrahydroaminoacridine: possi- Potential sources of artefact in the co-axial bioassay (203) 405 ble relationship to its capricious efficacy (203) 421 Kizu, A., see Yoshida, Y. (203) 173 Haas, U., see Tian, R. (203) 71 Kodama, I., see Shibata, S. (203) 337 Hamdi, A. and Kostrzewa, R.M Kostrzewa, R.M., see Hamdi, A. (203) 115 Ontogenic homologous supersensitization of dopamine D, recep- Kozikowski, A.P., see McKinney, M. (203) 303 tors (203) 115 Krieglistein, J., see Prehn, J.H.M. (203) 213 Hasegawa, S., see Ninomiya, H. (203) 299 Kuzmin, A., see Devoto, P. (203) 67 Hashimoto, T. and Fukuda, N Effect of thyrotropin-releasing hormone on the neurologic im- pairment in rats with spinal cord injury: treatment starting 24 h Lambert, N.A. and Teyler, T.J and 7 days after injury (203) 25 Cholinergic disinhibition in area CA1 of the rat hippocampus is Hechler, V., see Schmidt, C. (203) 393 not mediated by receptors located on inhibitory neurons (203) Hermansen, K., see Gregersen, S. (203) 111 129 Hester, R.K., see Shibata, S. (203) 337 Lambrecht, G., see Dérje, F. (203) 417 Hildebrand, L.M., see DeHaven-Hudkins, D.L. (203) 329 Langel, U., see Gregersen, S. (203) 111 Hill, R.J., Thakore, E., Taouis, M., Duff, H.J. and Sheldon, R.S Laubie, M., see Dabiré, H. (203) 323 Transcainide: biochemical evidence for state-dependent interac- Laubie, M., see Millan, M.J. (203) 319 tion with the class I antiarrhythmic drug receptor (203) 51 Lavielle, G., see Millan, M.J. (203) 319 Hisa, H., see Takagi, H. (203) 291 Leander, J.D., see Schoepp, D.D. (203) 237 Ho, I.K., see Horan, P. (203) 387 Lejeune, F., see Millan, M.J. (203) 319 Hojo, M., see Shibata, S. (203) 337 Lewis, $.J., Machado, B.H., Ohta, H. and Talman, W.T. Homma, I., see Inazu, M. (203) 79 Processing of cardiopulmonary afferent input within the nucleus Horan, P. and Ho, I.K. tractus solitarii involves activation of soluble guanylate cyclase The physical dependence liability of butorphanol: a comparative (203) 327 study with morphine (203) 387 Li, S., see Liu-Chen, L.-Y. (203) 195 Hrbas, P., see Zacharia, S. (203) 353 Light, P.E. and Publicover, S.J. Huidobro-Toro, J.P., see Bitran, M. (203) 267 Stimulation of miniature end-plate potential frequency by fluo- ride may involve activation of protein kinase C (203) 311 Igarashi, H., see Kamei, J. (203) 253 Liu-Chen, L.-Y., Li, S., Wheeler-Aceto, H. and Cowan, A Inazu, M., Sakai, Y. and Homma, | Effects of intracerebroventricular B-funaltrexamine on yu and 6 Contractile responses and calcium mobilization in renal arteries opioid receptors in the rat: dichotomy between binding and of diabetic rats (203) 79 antinociception (203) 195 Insel, T.R. and Winslow, J.T. Lodge, D., see Schoepp, D.D. (203) 237 Central administration of oxytocin modulates the infant rat's Lund, A., see Bang Olsen, U. (203) 133 response to social isolation (203) 149 Lundberg, J.M., see Delay-Goyet, P. (203) 157 Ishii, Y., see Ninomiya, H. (203) 299 Lundberg, J.M., see Modin, A. (203) 165 Isla, M., see Garcia-Pascual, A. (203) 259 Lunn, W.H.W., see Schoepp, D.D. (203) 237 Machado, B.H., see Lewis, $.J. (203) 327 Pani, L., see Devoto, P. (203) 67 Macrae, I., Robinson, M., McAuley, M., Reid, J. and McCulloch, J Pérgola, P.E. and Alper, R.H. Effects of intracisternal endothelin-1 injection on blood flow to Pharmacological evidence that circumventricular organs may par- the lower brain stem (203) 85 ticipate in the pressor effect of central serotonin (203) 145 Maggi, C.A., see Giuliani, S. (203) 365 Pernow, J., see Modin, A. (203) 165 Maitre, M., see Schmidt, C. (203) 393 Peruche, B., see Prehn, J.H.M. (203) 213 Marmol, F., Puig-Parellada, P. and Forn, J Pilotte, N.S., see Sharpe, L.G. (203) 141 Chronic treatment of guinea pigs with lithium chloride: effects on Piper, P.J., see Gunn, L.K. (203) 405 myenteric plexus preparations and on cyclic AMP levels (203) 181 Prehn, J.H.M., BackhauB, C., Karkoutly, C., Nuglisch, J., Peruche, Martinez, J., see Carles-Bonnet, C. (203) 245 B., RoBberg, C. and Krieglstein, J. McAuley, M., see Macrae, I. (203) 85 Neuroprotective properties of 5-HT,, receptor agonists in rodent McCulloch, J., see Macrae, I. (203) 85 models of focal and global cerebral ischemia (203) 213 McGivern, J. and Scholfield, C.N Publicover, S.J., see Light, P.E. (203) 311 Action of general anaesthetics on unclamped Ca**-mediated Puig-Parellada, P., see Marmol, F. (203) 181 currents in unmyelinated axons of rat olfactory cortex (203) 59 Pulzer, F., see Tian, R. (203) 71 McKinney, M., Miller, J.H.. Yamada, F., Tuckmantel, W. and Kozikowski, A.P Quartara, L., see Giuliani, S. (203) 365 Potencies and stereoselectivities of enantiomers of huperzine A Raatgeep, R., see Jongejan, R. (203) 187 for inhibition of rat cortical acetylcholinesterase (203) 303 Reid, J., see Macrae, I. (203) 85 Mennini, T., see Borsini, F. (203) 359 Rettenmayr, N.M., see Dorje, F. (203) 417 Michael-Titus, A., see Bousselmame, R. (203) 295 Rivet, J.-M., see Millan, M.J. (203) 319 Micheletti, R., see Turconi, M. (203) 203 Rizzi, C., see Turconi, M. (203) 203 Millan, M.J., Canton, H., Rivet, J.-M., Lejeune, F., Laubie, M. and Robinson, M., see Macrae, 1. (203) 85 Lavielle, G RoBberg, C., see Prehn, J.H.M. (203) 213 S 14671: A novel naphthylpiperazine 5-HT,, agonist of high Rossuwski, W_J., see Zacharia, S$. (203) 353 efficacy and exceptional in vivo potency (203) 319 Rovero, P., see Giuliani, S. (203) 365 Millan, MJ Antagonists at the NMDA recognition site and blockers of the Sacaan, A.I., see Schoepp, D.D. (203) 237 associated ion channel induce spontaneous tail-flicks in the rat Safar, M., see Dabiré, H. (203) 323 (203) 315 Sagrada, A., see Turconi, M. (203) 203 Millar, J.D., see Schoepp, D.D. (203) 237 Saha, N., see Chugh, Y. (203) 121 Miller, J.H., see McKinney, M. (203) 303 Sakai, Y., see Inazu, M. (203) 79 Miller, R., see Trullas, R. (203) 379 Sala, R., Moriggi, E., Della Bella, D. and Carenzi, A. Miranda, F.J., see Salom, J.B. (203) 33 The specific binding of broxaterol, a new B,-selective agonist, to Mitchell, W.M., see Sharpe, L.G. (203) 141 B-adrenoceptors (203) 17 Miyagishi, T., see Yoshida, Y. (203) 173 Salom, J.B., Torregrosa, G., Miranda, F.J., Alabadi, J.A., Alvarez, C Modin, A., Pernow, J. and Lundberg, J.M and Alborch, E Evidence for two neuropeptide Y receptors mediating vasocon Ca** entry blockers inhibit prostaglandin F,,-induced cere- striction (203) 165 brovascular contractile responses in goats (203) 33 Montagna, E., see Turconi, M. (203) 203 Sankaranarayanan, A., see Chugh, Y. (203) 121 Mordvintcev, P.I., see Galagan, M.E. (203) 325 Saotome, M., see Ninomiya, H. (203) 299 Mori, T., see Kamei, J. (203) 253 Satake, N., see Shibata, S. (203) 337 Moriggi, E., see Sala, R. (203) 17 Satoh, S., see Takagi, H. (203) 291 Morris, J.L. Schaus, J.M., see Seeman, P. (203) 105 Pertussis toxin attenuates postsynaptic actions of neuropeptide Y Schiavone, A., see Turconi, M. (203) 203 on the guinea-pig uterine artery (203) 275 Schmidt, C., Gobaille, S., Hechler, V., Schmitt, M., Bourguignon Mutschler, E., see Dorje, F. (203) 417 J.-J. and Maitre, M. Anti-sedative and anti-cataleptic properties of NCS-382, a y-hy- Neubauer, S., see Tian, R. (203) 71 droxybutyrate receptor antagonist (203) 393 Nicola, M., see Turconi, M. (203) 203 Schmidt, C.J., Black, C.K. and Taylor, V.L. Niel, H., see Carles-Bonnet, C. (203) 245 L-DOPA potentiation of the serotonergic deficits due to a single Nimmo, A.J., see Barr, A.J. (203) 287 administration of 3,4-methylenedioxymethamphetamine, p-chlo- roamphetamine or methamphetamine to rats (203) 41 Ninomiya, H., Uchida, Y., Ishii, Y., Nomura, A., Kameyama, M.., Schmitt, H., see Dabiré, H. (203) 323 Saotome, M., Endo, T. and Hasegawa, S Schmitt, M., see Schmidt, C. (203) 393 Endotoxin stimulates endothelin release from cultured epithelial Schoepp, D.D., Smith, C.L., Lodge, D., Millar, J.D., Leander, J.D., cells of guinea-pig trachea (203) 299 Sacaan, A.I. and Lunn, W.H.W Nomura, A., see Ninomiya, H. (203) 299 Nuglisch, J., see Prehn, J.H.M. (203) 213 D,L-4Tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist (203) 237 Scholfield, C.N., see McGivern, J. (203) 59 Ogawa, T., see Kawamura, T. (203) 399 Seeman, P. and Schaus, J.M. Ohta, H., see Lewis, S.J. (203) 327 Dopamine receptors labelled by [*H]quinpirole (203) 105 Ono, H., Ono, S.-S. and Fukuda, H Sharma, P.L., see Chugh, Y. (203) 121 5-HT receptor-mediated regulation of thyrotropin-releasing hor- Sharpe, L.G., Pilotte, N.S., Mitchell, W.M. and De Souza, E.B mone release in rat spinal cord (203) 283 Withdrawal of repeated cocaine decreases autoradiographic Ono, S.-S., see Ono, H. (203) 283 {*H]}mazindol-labelling of dopamine transporter in rat nucleus Ono, T., see Yoshida, Y. (203) 173 accumbens (203) 141 428 Sheldon, R.S., see Hill, R.J. (203) 51 Pharmacological properties of a novel class of 5-HT, receptor Shibata, S., Satake, N., Kodama, I., Hester, R.K., Wang, C.-G., Jino antagonists (203) 203 H., Hojo, M., Tatsumi, H., Gandhi, V. and Jones, DJ Turini, D., see Giuliani, S. (203) 365 Pharmacological characteristics of NP-252, a new dihydropyridine slow Ca** channel blocker, in isolated rabbit vascular smooth Uchida, Y., see Ninomiya, H. (203) 299 muscle and guinea pig myocardium: vascular selectivity (203) 337 Skolnick, P., see Trullas, R. (203) 379 Van Furth, W.R., Wiegant, V.M., Bruning, J.W. and Van Ree, J.M Smith, C.L., see Schoepp, D.D. (203) 237 The grasping response in rats: interaction between y-type endor- Spear, L.P., Frambes, N.A. and Goodwin, G phins and haloperidol (203) 413 Low doses of the 5-HT,, receptor agonist 8-OH-DPAT increase Vanin, A.F., see Galagan, M.E. (203) 325 ingestive behavior in late preweanling and postweanling, but not Van Ree, J.M., see Van Furth, W.R. (203) 413 neonatal rat pups (203) 9 Verdonck, F., Bielen, F.V. and Ver Donck, I Sperelakis, N., see Tohse, N. (203) 307 Preferential block of the veratridine-induced, non-inactivating Stijnen, T., see Jongejan, R. (203) 187 Na” current by R56865 in single cardiac Purkinje cells (203) 371 Stjarne, L., see Bao, J.-X. (203) 159 Ver Donck, L., see Verdonck, F. (203) 371 St Pierre, S., see Bitran, M. (203) 267 Vidi, A., see Borsini, F. (203) 359 Sutak, M., see Cridland, R.A. (203) 93 Vulliemoz, Y The myocardial depressant effect of volatile anesthetics does not Takagi, H., Hisa, H. and Satoh, S involve arachidonic acid metabolites or pertussis toxin-sensitive G Effects of endothelin on adrenergic neurotransmission in the dog proteins (203) 345 kidney (203) 291 alman, W.T., see Lewis, S.J. (203) 327 anihara, H., see Kamei, J. (203) 153 adsworth, R.M., see Demiryurek, A.T. (203) 1 aouis, M., see Hill, R.J. (203) 51 Wang, C.-G., see Shibata, S. (203) 337 atsumi, H., see Shibata, S. (203) 337 Ward, S.J., see DeHaven-Hudkins, D.L. (203) 329 Watson, S.P., see Barr, A.J. (203) 287 Taylor, V.L., see Schmidt, C.J. (203) 41 Teyler, T.J., see Lambert, N.A. (203) 129 Wheeler-Aceto, H., see Liu-Chen, L.-Y. (203) 195 Wiegant, V.M., see Van Furth, W.R. (203) 413 Thakore, E., see Hill, R.J. (203) 51 Tian, R., Neubauer, S., Pulzer, F., Haas, U. and Ertl, G Winslow, J.T., see Insel, T.R. (203) 149 Angiotensin I conversion and coronary constriction by an giotensin Il in ischemic and hypoxic isolated rat hearts (203) 71 Yamada, F., see McKinney, M. (203) 303 Tohse, N., Conforti, L. and Sperelakis, N Yoshida, Y., Ono, T., Kizu, A., Fukushima, R. and Miyagishi, T Bay K 8644 enhances Ca~* channel activities in embryonic chick Striatal N-methyl-D-aspartate receptors in haloperidol-induced heart cells without prolongation of open times (203) 307 catalepsy (203) 173 Torregrosa, G., see Salom, J.B. (203) 33 Young, A., see Trullas, R. (203) 379 Torres, G., see Bitran, M. (203) 267 Towles, J., see Kiefer-Day, J.S. (203) 421 Zacharia, S., Rossowski, W.J., Jiang, N.-Y., Hrbas, P., Ertan, A. and Trullas, R., Folio, T., Young, A., Miller, R., Boje, K. and Skolnick, P Coy, D.H 1-Aminocyclopropanecarboxylates exhibit antidepressant and New reduced peptide bond substance P agonists and antagonists anxiolytic actions in animal models (203) 379 effects on smooth muscle contraction (203) 353 Tuckmantel, W., see McKinney, M. (203) 303 Zhang, A., Carella, A., Altura, B.T. and Altura, B.M Turconi, M., Donetti, A., Schiavone, A., Sagrada, A., Montagna, E Interactions of magnesium and chloride ions on tone and con Nicola, M., Cesana, R., Rizzi, C. and Micheletti, R tractility of vascular muscle (203) 223 European Journal of Pharmacology, 203 (1991) 429-438 © 1991 Elsevier Science Publishers B.V. All rights reserved 0014-2999 /9] $03.50 Key word index Acetorphan Alphaxalone Desensitization; u-Opioid receptors; 5-Opioid receptors; Analgesia Halothane; Ketamine; Pentobarbitone; Urethane; Ether; Diisopro- (Bousselmame, R. (203) 295) pylphenol; Lignocaine; Ca** currents (axonal); Olfactory cortex (McGivern, J. (203) 59) Acetylcholine Cholinomimetics; Cerebral cortex; Stereochemistry; Alzheimer's dis Alzheimer’s disease ease; (Natural products) (McKinney, M. (203) 303) Acetylcholine; Cholinomimetics; Cerebral cortex; Stereochemistry; (Natural products) (McKinney, M. (203) 303) ACPC (1l-aminocyclopropanecarboxylic acid) NMDA (N-methyl-D-aspartate); Strychnine-insensitive glycine re cAMP ceptors; Plus-maze; Forced swimming test (Trullas, R. (203) 379) LiCl; Adenylate cyclase; Myenteric plexus; LiCl-treated animals (chronically), Phosphodiesterase inhibitors; (Isolated organ bath) A-delta afferents (Marmol, F. (203) 181) GABA , receptors; Ca Sensory neurones; Ca pools (intracellu AMPA receptors lar); Caffeine; Ryanodine (Desaulles, E. (203) 137) NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo( F quinoxaline) ; Pain reflex; (Rat) (Bang Olsen, U. (203) 133) Adenylate cyclase LiCl; cAMP; Myenteric plexus; LiCl-treated animals (chronically) Anaesthetics (volatile) Phosphodiesterase inhibitors; (Isolated organ bath) (Marmol, F. (203) Halothane; Isoflurane; Arachidonic acid cascade; G-proteins; My 181) ocardial contractility; (Rat) (Vulliemoz, Y. (203) 345) Adrenoceptors Analgesia Urethra; (Lamb) (Garcia-Pascual, A. (203) 259) Desensitization; p-Opioid receptors; 5-Opioid receptors; Acetor phan (Bousselmame, R. (203) 295) a@,-Adrenoceptors (prejunctional) ATP: Electrochemistry; Noradrenaline (endogenous), Extracellular Anaphylactic shock recording; SK&F 104078 (Bao, J.-X. (203) 159) Nitric oxide (NO); L-NAME (N“-nitro-L-arginine methyl ester) (Mouse) (Amir, S. (203) 125) B-Adrenoceptors B,-Adrenoceptor-selective agonists; Broxaterol; Thermodynamics; Angiotensin | Enthalpy changes; Entropy changes (Sala, R. (203) 17) Angiotensin Il; Angiotensin-converting enzyme (cardiac); Heart (iso lated), Coronary flow; Ischemia; Hypoxia (Tian, R. (203) 71) B,-Adrenoceptor-selective agonists B-Adrenoceptors; Broxaterol; Thermodynamics; Enthalpy changes Angiotensin Il Entropy changes (Sala, R. (203) 17) Angiotensin I; Angiotensin-converting enzyme (cardiac), Heart (iso lated), Coronary flow; Ischemia; Hypoxia (Tian, R. (203) 71) Affiliation Oxytocin; Ultrasonic vocalization; Anxiety; Thermoregulation (Insel Angiotensin-converting enzyme (cardiac) Angiotensin I; Angiotensin II; Heart (isolated); Coronary flow; Is T.R. (203) 149) chemia; Hypoxia (Tian, R. (203) 71) Airway Anion exchange inhibitors Co-axial bioassay; EpDRF (epithelium-derived relaxant factor), Tra chea (guinea-pig); Bronchus (rabbit); Aorta (rat) (Gunn, L.K. (203) Smooth muscle (vascular), Cl ions; Isethionate;: Ca movement Cl” channels; Caffeine (Zhang, A. (203) 223) 405) Antianginal agent Airway epithelial cells E4080; Bradycardiac agents; Coronary vasodilating action; ATP-sen Endothelin; Endotoxin (Ninomiya, H. (203) 299) sitive K* channels; Glibenclamide (Kawamura, T. (203) 399) Airway muscle (human) Antiarrhythmic drugs Bronchial hyperresponsiveness; Inflammatory mediators; Epithe Batrachotoxinin; Na*~ channels; State-dependent binding (Hill, RJ lium; Mast cell activation; Anti-human immunoglobulin E Jongejan (203) 51) R. (203) 187) Anti-human immunoglobulin E Allosteric antagonists Airway muscle (human); Bronchial hyperresponsiveness; Inflamma Tetrahydroaminoacridine; Muscarinic receptors; Muscarinic receptor tory mediators; Epithelium; Mast cell activation (Jongejan, R. (203) subtypes; Brain; (Rat) (Kiefer-Day, J.S. (203) 421) 187) 430 Antinociception Bronchial hyperresponsiveness B-Funaltrexamine; Opioid receptor binding (Liu-Chen, L.-Y. (203) Airway muscle (human); Inflammatory mediators; Epithelium; Mast 195) cell activation; Anti-human immunoglobulin E (JJongejan, R. (203) 187) Antitussive effects p-Opioid receptors; 5-Opioid receptors; Cough reflex; Naltrindole; Bronchus (rabbit) (Rat) (Kamei, J. (203) 153) Co-axial bioassay; EpDRF (epithelium-derived relaxant factor); Air- way; Trachea (guinea-pig); Aorta (rat) (Gunn, L.K. (203) 405) Antitussives Cough reflex; 5-HT receptors; 8-OH-DPAT (8-hydroxy-2-(di-n-pro Broxaterol pylamino)tetralin); 5-HT,, receptors (Kamei, J. (203) 253) B-Adrenoceptors; 8,-Adrenoceptor-selective agonists; Thermody- namics; Enthalpy changes; Entropy changes (Sala, R. (203) 17) Anxiety Oxytocin; Ultrasonic vocalization; Thermoregulation; Affiliation (In Butorphanol sel, T.R. (203) 149) Morphine; Withdrawal (precipitated and abrupt), Physical depen- dence (Horan, P. (203) 387) Aorta (rat) Co-axial bioassay; EpDRF (epithelium-derived relaxant factor); Air Ca. * 2+ way; Trachea (guinea-pig); Bronchus (rabbit) (Gunn, L.K. (203) 405) GABA, receptors; Sensory neurones; Ca~* pools (intracellular), Caffeine; Ryanodine; A-delta afferents (Desaulles, E. (203) 137) Arachidonic acid cascade Anaesthetics (volatile); Halothane; Isoflurane; G-proteins; Myocar Muscarinic M, heteroreceptors (prejunctional); Muscarinic receptor dial contractility; (Rat) (Vulliemoz, Y. (203) 345) agonists; Vas deferens (rabbit); Pirenzepine; 4-Cl-McN-A-343 (Dorje, F. (203) 417) ATP Electrochemistry; Noradrenaline (endogenous); Extracellular record Ca** binding ing; a@»-Adrenoceptors (prejunctional); SK&F 104078 (Bao, J.-X Ca~* channel blockers; Smooth muscle (vascular); Cardiac muscle; (203) 159) Ca* uptake; Tissue selectivity; (Slow response) (Shibata, S. (203) 337) ATP-sensitive K * channels Ca** channel agonists E4080; Bradycardiac agents; Coronary vasodilating action; Gliben Heart cells (cultured); Heart cells (embryonic); Patch clamp analysis; clamide; Antianginal agent (Kawamura, T. (203) 399) Ca-~ channels (L-type); Single channel currents (Tohse, N. (203) 307) Baclofen Carbachol; Inhibitory postsynaptic potentials (monosynaptic); Phor Ca** channel antagonists bol esters; (Disinhibition) (Lambert, N.A. (203) 129) Cocaine; Dopamine uptake; Striatal synaptosomes (Devoto, P. (203) 67) Batrachotoxinin Antiarrhythmic drugs; Na“ channels; State-dependent binding (Hill, Ca** channel blockers R.J. (203) 51) Smooth muscle (vascular); Cardiac muscle; Ca** uptake; Tissue selec- tivity; Ca~* binding; (Slow response) (Shibata, S. (203) 337) Benzimidazolone derivatives 5-HT, receptors; 5-HT, receptors; Prokinetic activity (Turconi, M Ca** channels (203) 203) Diabetes; Renal artery; Hyperreactivity; Hyperpermeability (Inazu, M. (203) 79) Blood pressure 5-HT (5-hydroxytryptamine, serotonin); Circumventricular organs; Ca?* channels (L-type) Xylamidine; (Conscious rat) (Pérgola, P.E. (203) 145) Heart cells (cultured); Heart cells (embryonic); Patch clamp analysis; Single channel currents; Ca** channel agonists (Tohse, N. (203) 307) Bradycardiac agents E4080; Coronary vasodilating action; ATP-sensitive K* channels; Ca** currents (axonal) Glibenclamide; Antianginal agent (Kawamura, T. (203) 399) Halothane; Ketamine; Pentobarbitone; Urethane; Ether; Alphax- alone; Diisopropylphenol; Lignocaine; Olfactory cortex (McGivern, Brain J. (203) 59) Tetrahydroaminoacridine; Muscarinic receptors; Muscarinic receptor subtypes; Allosteric antagonists; (Rat) (Kiefer-Day, J.S. (203) 421) Ca** entry blockers Prostaglandin F,,; Cerebral blood flow; Middle cerebral artery; Brain (guinea-pig) Ca**-free medium (Salom, J.B. (203) 33) o Receptors; Vas deferens (mouse); Twitch contractions (electrically stimulated) (DeHaven-Hudkins, D.L. (203) 329) Caffeine GABA , receptors; Ca**; Sensory neurones; Ca?* pools (intracellu- Brain (rat) lar); Ryanodine; A-delta afferents (Desaulles, E. (203) 137) y-Hydroxybutyrate receptors; y-Hydroxybutyrate receptor antago- nists; Sedative /anaesthetic effects; NCS-382; Catalepsy; Neurolep- Smooth muscle (vascular); Cl~ ions; Isethionate: Ca** movement: tics (Schmidt, C. (203) 393) Anion exchange inhibitors; Cl~ channels (Zhang, A. (203) 223) Ca**-free medium p-Chloroamphetamine Prostaglandin F,,; Cerebral blood flow; Middle cerebral artery; MDMA(3,4-methylenedioxymethamphetamine); Methamphetamine; Ca** entry blockers (Salom, J.B. (203) 33) Fenfluramine; Dopamine/serotonin neurotoxicity (Schmidt, C.J. (203) 41) Ca** movement Smooth muscle (vascular); Cl” ions; Isethionate; Anion exchange Cholinomimetics inhibitors; Cl” channels; Caffeine (Zhang, A. (203) 223) Acetylcholine; Cerebral cortex; Stereochemistry; Alzheimer’s dis- ease; (Natural products) (McKinney, M. (203) 303) Ca’** pools (intracellular) GABA, receptors; Ca**: Sensory neurones; Caffeine; Ryanodine; Circumventricular organs A-delta afferents (Desaulles, E. (203) 137) 5-HT (5-hydroxytryptamine, serotonin); Blood pressure; Xylamidine; (Conscious rat) (Pérgola, P.E. (203). 145) Carbachol Baclofen; Inhibitory postsynaptic potentials (monosynaptic), Phorbol Cl” channels esters; (Disinhibition) (Lambert, N.A. (203) 129) Smooth muscle (vascular); Cl~ ions; Isethionate; Ca?* movement; Anion exchange inhibitors; Caffeine (Zhang, A. (203) 223) Cardiac cells Na” currents; Veratridine; Cardioprotection; (Block) (Verdonck, F (203) 371) Cl” ions Smooth muscle (vascular); Isethionate; Ca2* movement; Anion ex- Cardiac muscle change inhibitors; Cl” channels; Caffeine (Zhang, A. (203) 223) Ca** channel blockers; Smooth muscle (vascular); Ca** uptake; Tis- sue selectivity; Ca?* binding; (Slow response) (Shibata, S. (203) 337) 4-Cl-McN-A-343 Muscarinic M, heteroreceptors (prejunctional); Muscarinic receptor Cardioprotection agonists; Vas deferens (rabbit); Ca?*; Pirenzepine (Dérje, F. (203) Na~ currents; Veratridine; Cardiac cells; (Block) (Verdonck, F 417) (203) 371) Co-axial bioassay Castration /neurotransmission EpDRF (epithelium-derived relaxant factor); Airway; Trachea Neuropeptide Y (NPY); Vas deferens; Neurotransmission; Hor- (guinea-pig); Bronchus (rabbit); Aorta (rat) (Gunn, L.K. (203) 405) monal regulation; (Age and castration); (Rat) (Bitran, M. (203) 267) Cocaine Catalepsy Ca** channel antagonists; Dopamine uptake; Striatal synaptosomes Haloperidol; NMDA receptors; Dopamine; Glutamate; Caudate- (Devoto, P. (203) 67) putamen; (Rat) (Yoshida, Y. (203) 173) Colon (human) y-Hydroxybutyrate receptors; y-Hydroxybutyrate receptor antago- Tachykinins; Tachykinin receptors; Tachykinin receptor antagonists; nists; Sedative /anaesthetic effects; Brain (rat); NCS-382; Neurolep- NK, receptor subtypes (Giuliani, S. (203) 365) tics (Schmidt, C. (203) 393) Caudate-putamen Convulsions Catalepsy; Haloperidol; NMDA receptors; Dopamine; Glutamate; NMDA (N-methyl-D-aspartate); Excitatory amino acids (Schoepp, (Rat) (Yoshida, Y. (203) 173) D.D. (203) 237) Ca* uptake Coronary flow Ca** channel blockers; Smooth muscle (vascular); Cardiac muscle; Angiotensin 1; Angiotensin II; Angiotensin-converting enzyme Tissue selectivity; Ca** binding; (Slow response) (Shibata, S. (203) (cardiac), Heart (isolated), Ischemia; Hypoxia (Tian, R. (203) 71) 337) Coronary vasodilating action Cerebral blood flow E4080; Bradycardiac agents; ATP-sensitive K* channels; Gliben- Prostaglandin F,,,; Middle cerebral artery; Ca? *-free medium; Ca?* clamide; Antianginal agent (Kawamura, T. (203) 399) entry blockers (Salom, J.B. (203) 33) Cough reflex Endothelin-1; Ischaemia; Ischaemic pressor response (Macrae, | p-Opioid receptors; 5-Opioid receptors; Antitussive effects; Nal- (203) 85) trindole; (Rat) (Kamei, J. (203) 153) Cerebral cortex Antitussives; 5-HT receptors; 8-OH-DPAT (8-hydroxy-2-(di-n-pro- Acetylcholine; Cholinomimetics; Stereochemistry; Alzheimer’s dis- pylamino)tetralin), 5-HT,, receptors (Kamei, J. (203) 253) ease; (Natural products) (McKinney, M. (203) 303) Cerebral ischemia CPP (3-(2-carboxypiperazin-4-yl)-propyl-i-phosphonic acid) 5-HT,, receptor agonists; Neuroprotection; Hypothermia (Prehn, NMDA (N-methyl-D-aspartate); MK 801; Phencyclidine (PCP), CGS J.H.M. (203) 213) 19755; 5-HT,, receptors; Tail flicks (spontaneous) (Millan, MJ (203) 315) CGS 19755 NMDA (N-methyl-D-aspartate); MK 801; Phencyclidine (PCP); CPP Desensitization (3-(2-carboxypiperazin-4-yl)-propyl-l-phosphonic acid); 5-HT,, re- p-Opioid receptors; 5-Opioid receptors; Acetorphan; Analgesia ceptors; Tail flicks (spontaneous) (Millan, M.J. (203) 315) (Bousselmame, R. (203) 295) 432 Desipramine Endotoxin Forced swimming test; Imipramine; 5-HT receptor antagonists Endothelin; Airway epithelial cells (Ninomiya, H. (203) 299) (Mouse) (Borsini, F. (203) 359) [Met* Jenkephalin levels Diabetes Spinal morphine; Physical dependence; Morphine withdrawal (Crid- Renal artery; Ca channels; Hyperreactivity; Hyperpermeability land, R.A. (203) 93) (Inazu, M. (203) 79) Enthalpy changes Diisopropylphenol B-Adrenoceptors; £,-Adrenoceptor-selective agonists; Broxaterol; Halothane; Ketamine: Pentobarbitone; Urethane; Ether: Alphax Thermodynamics; Entropy changes (Sala, R. (203) 17) alone; Lignocaine; Ca currents (axonal); Olfactory cortex (Mc Givern, J. (203) 59) Entropy changes B-Adrenoceptors; £,-Adrenoceptor-selective agonists; Broxaterol; Dopamine Thermodynamics; Enthalpy changes (Sala, R. (203) 17) Dopamine receptors; Quinpirole; Striatum; Neuroleptics (Seeman, P. (203) 105) EpDRF (epithelium-derived relaxant factor) Co-axial bioassay; Airway; Trachea (guinea-pig); Bronchus (rabbit); Ontogeny; Dopamine D, receptors; 6-Hydroxydopamine (6-OHDA); Aorta (rat) (Gunn, L.K. (203) 405) SK&F 38393; Supersensitization (Hamdi, A. (203) 115) Epithelium Catalepsy; Haloperidol; NMDA receptors; Glutamate: Caudate Airway muscle (human); Bronchial hyperresponsiveness; Inflamma putamen; (Rat) (Yoshida, Y. (203) 173) tory mediators; Mast cell activation; Anti-human immunoglobulin (Jongejan, R. (203) 187) Dopamine receptors Dopamine; Quinpirole; Striatum; Neuroleptics (Seeman, P. (203) Ether 105) Halothane; Ketamine; Pentobarbitone; Urethane; Alphaxalone; Di- isopropylphenol; Lignocaine; Ca** currents (axonal); Olfactory cor Dopamine D, receptors tex (McGivern, J. (203) 59) Ontogeny; Dopamine; 6-Hydroxydopamine (6-OHDA),; SK&F 38393 Supersensitization (Hamdi, A. (203) 115) Excitatory amino acids NMDA (N-methyl-D-aspa:tate); Convulsions (Schoepp, D.D. (203) Dopamine/serotonin neurotoxicity 237) MDMA(3.4-methylenedioxymethamphetamine); p-Chloroampheta mine; Methamphetamine: Fenfluramine (Schmidt, C.J. (203) 41) Extracellular recording ATP; Electrochemistry; Noradrenaline (endogenous); a .,-Adreno- Dopamine uptake ceptors (prejunctional); SK&F 104078 (Bao, J.-X. (203) 159) Cocaine; Ca? channel antagonists; Striatal synaptosomes (Devoto, P. (203) 67) Fenfluramine MDMA(3,4-methylenedioxymethamphetamine);, p-Chloroampheta- Sensitization; Striatum; Down-regulation (Sharpe, L.G. (203) 141) mine; Methamphetamine; Dopamine/serotonin neurotoxicity (Schmidt, C.J. (203) 41) Down-regulation Sensitization; Striatum; Dopamine uptake (Sharpe, L.G. (203) 141) Flurbiprofen Duodenum (rat) Hypoxia; Intrapulmonary artery rings (sheep); Verapamil (De- Substance P; Substance P analogues (hepta- and hexapseudopeptide); miryurek, A.T. (203) 1) Spantide; NK, receptors; NK, receptors; Ileum (guinea-pig) (Zacharia, §. (203) 353) Forced swimming test Imipramine; Desipramine; 5-HT,,. receptor antagonists; (Mouse) E4080 (Borsini, F. (203) 359) Bradycardiac agents; Coronary vasodilating action; ATP-sensitive K* channels; Glibenclamide; Antianginal agent (Kawamura, T. (203) ACPC (l-aminocyclopropanecarboxylic acid); NMDA (N-methyl-D- 399) aspartate); Strychnine-insensitive glycine receptors; Plus-maze (Trul- las, R. (203) 379) Electrochemistry ATP; Noradrenaline (endogenous); Extracellular recording; a, 8 -Funaltrexamine Adrenoceptors (prejunctional); SK&F 104078 (Bao, J.-X. (203) 159) Opioid receptor binding; Antinociception (Liu-Chen, L.-Y. (203) 195) Endorphins (y -type) Haloperidol; Grasping response (Van Furth, W.R. (203) 413) GABA, receptors Ca**; Sensory neurones; Ca?” pools (intracellular); Caffeine; Ryan- Endothelin-1 odine; A-delta afferents (Desaulles, E. (203) 137) Cerebral blood flow; Ischaemia; Ischaemic pressor response (Mac- rae, 1. (203) 85) Galanin Pancreatic islets; Insulin secretion (Gregersen, S. (203) 111) Norepinephrine release; Renal blood flow; (Dog) (Takagi, H. (203) 291) Gastric acid secretion Histamine; Oxyntomodulin; Oxyntomodulin fragments; (Conscious Endotoxin; Airway epithelial cells (Ninomiya, H. (203) 299) rat) (Carles-Bonnet, C. (203) 245) Glibenclamide 5-HT,, receptor agonists E4080; Bradycardiac agents; Coronary vasodilating action; ATP-sen 5-HT,, autoreceptors; Ingestion; 8-OH-DPAT (8-hydroxy-2-4di-n- sitive K* channels; Antianginal agent (Kawamura, T. (203) 399) propylamino)tetralin); Ontogeny (Spear, L.P. (203) 9) Glutamate Cerebral ischemia; Neuroprotection; Hypothermia (Prehn, J.H.M Catalepsy; Haloperidol; NMDA receptors; Dopamine; Caudate (203) 213) putamen; (Rat) (Yoshida, Y. (203) 173) 5-HT, receptor antagonists G-proteins Memory; (Mouse) (Chugh, Y. (203) 121) Neuropeptide Y (NPY); VIP (vasoactive intestinal polypeptide); 5-HT,,. receptor antagonists Vasoconstriction; Pertussis toxin (Morris, J.L. (203) 275) Forced swimming test; Imipramine; Desipramine; (Mouse) (Borsini, Transmitter release; Miniature end-plate potential—fluoride; Protein F. (203) 359) kinase C (Light, P.E. (203) 311) 5-HT receptors Cough reflex; Antitussives; 8-OH-DPAT (8-hydroxy-2-di-n-pro- Anaesthetics (volatile); Halothane; Isoflurane; Arachidonic acid cas pylamino)tetralin), 5-HT,, receptors (Kamei, J. (203) 253) cade; Myocardial contractility; (Rat) (Vulliemoz, Y. (203) 345) 5-HT,, receptors Grasping response Cough reflex; Antitussives; 5-HT receptors; 8-OH-DPAT (8-hydroxy- Haloperidol; Endorphins (y-type) (Van Furth, W.R. (203) 413) 24di-n-propylamino)}tetralin) (Kamei, J. (203) 253) Haloperidol NMDA (N-methyl-D-aspartate); MK 801; Phencyclidine (PCP); CPP Catalepsy; NMDA receptors; Dopamine; Glutamate; Caudate-puta- (342-carboxypiperazin-4-yl)-propyl-l-phosphonic acid); CGS 19755; men; (Rat) (Yoshida, Y. (203) 173) Tail flicks (spontaneous) (Millan, M.J. (203) 315) Grasping response; Endorphins (y-type) (Van Furth, W.R. (203) 413) S 14671; 8-OH-DPAT (8-hydroxy-2-4di-n-propylamino)tetralin); Naphthylpiperazine; Tail flick (spontaneous) (Millan, M.J. (203) 319) Halothane Ketamine; Pentobarbitone; Urethane; Ether; Alphaxalone; Diiso- 5-HT, receptors propylphenol; Lignocaine; Ca** currents (axonal); Olfactory cortex 5-HT, receptors; Benzimidazolone derivatives; Prokinetic activity (McGivern, J. (203) 59) (Turconi, M. (203) 203) Anaesthetics (volatile); Isoflurane; Arachidonic acid cascade; G-pro- 5-HT, receptors teins; Myocardial contractility; (Rat) (Vulliemoz, Y. (203) 345) 5-HT, receptors; Benzimidazolone derivatives; Prokinetic activity (Turconi, M. (203) 203) Heart cells (cultured) Heart cells (embryonic); Patch clamp analysis; Ca** channels (1 y -Hydroxybutyrate receptor antagonists type); Single channel currents; Ca** channel agonists (Tohse, N y-Hydroxybutyrate receptors; Sedative /anaesthetic effects; Brain (203) 307) (rat); NCS-382; Catalepsy; Neuroleptics (Schmidt, C. (203) 393) Heart cells (embryonic) y -Hydroxybutyrate receptors y-Hydroxybutyrate receptor antagonists; Sedative /anaesthetic ef Heart cells (cultured); Patch clamp analysis; Ca** channels (1 -type); Single channel currents; Ca~~ channel agonists (Tohse, N. (203) 307) fects; Brain (rat); NCS-382; Catalepsy; Neuroleptics (Schmidt, C (203) 393) Heart (isolated) 6-Hydroxydopamine (6-OHDA) Angiotensin I; Angiotensin II; Angiotensin-converting enzyme Ontogeny; Dopamine; Dopamine D, receptors; SK&F 38393; Super- (cardiac); Coronary flow; Ischemia; Hypoxia (Tian, R. (203) 71) sensitization (Hamdi, A. (203) 115) Histamine Hyperpermeability Oxyntomodulin; Oxyntomodulin fragments; Gastric acid secretion; Diabetes; Renal artery; Ca** channels; Hyperreactivity (Inazu, M (Conscious rat) (Carles-Bonnet, C. (203) 245) (203) 79) Hormonal regulation Hyperreactivity Neuropeptide Y (NPY); Vas deferens; Neurotransmission; Castra- Diabetes; Renal artery; Ca** channels; Hyperpermeability (Inazu, tion /neurotransmission; (Age and castration); (Rat) (Bitran, M. (203) M. (203) 79) 267) Hypothermia 5-HT,, autoreceptors 5-HT,, receptor agonists; Cerebral ischemia; Neuroprotection 5-HT,, receptor agonists; Ingestion; 8-OH-DPAT (8-hydroxy-2-(di- (Prehn, J.H.M. (203) 213) n-propylamino)tetralin); Ontogeny (Spear, L.P. (203) 9) Hypoxia 5-HT (5-hydroxytryptamine, serotonin) Intrapulmonary artery rings (sheep); Flurbiprofen; Verapamil (De- Circumventricular organs; Blood pressure; Xylamidine; (Conscious miryurek, A.T. (203) 1) rat) (Pérgola, P.E. (203) 145) Angiotensin I; Angiotensin I]; Angiotensin-converting enzyme Thyrotropin-releasing hormone (TRH) release; Spinal cord (Ono, H (cardiac), Heart (isolated); Coronary flow; Ischemia (Tian, R. (203) (203) 283) 71) 434 lleum (guinea-pig) Lignocaine Substance P; Substance P analogues (hepta- and hexapseudopeptide); Halothane; Ketamine; Pentobarbitone; Urethane; Ether; Alphax- Spantide; NK, receptors; NK, receptors; Duodenum (rat) (Zacharia, alone; Diisopropylphenol; Ca? * currents (axonal); Olfactory cortex S. (203) 353) (McGivern, J. (203) 59) Imipramine Mast cell activation Forced swimming test; Desipramine; 5-HT,,. receptor antagonists; Airway muscle (human); Bronchial hyperresponsiveness; Inflamma- (Mouse) (Borsini, F. (203) 359) tory mediators; Epithelium; Anti-human immunoglobulin E (Jonge- jan, R. (203) 187) Inflammatory mediators Airway muscle (human); Bronchial hyperresponsiveness; Epithelium; MDMaA(3,4-methylenedioxymethamphetamine ) Mast cell activation; Anti-human immunoglobulin E (VJJongejan, R p-Chloroamphetamine; Methamphetamine; Fenfluramine; Dopa- (203) 187) mine /Serotonin neurotoxicity (Schmidt, C.J. (203) 41) Ingestion Memory 5-HT,, receptor agonists; 5-HT,, autoreceptors; 8-OH-DPAT (8 5-HT, receptor antagonists; (Mouse) (Chugh, Y. (203) 121) hydroxy-2-(di-n-propylamino)tetralin); Ontogeny (Spear, L.P. (203) 9) Methamphetamine Inhibitory postsynaptic potentials (monosynaptic) MDMA(3,4-methylenedioxymethamphetamine); p-Chloroampheta- Carbachol; Baclofen; Phorbol esters; (Disinhibition) (Lambert, N.A mine; Fenfluramine; Dopamine/serotonin neurotoxicity (Schmidt, (203) 129) C.J. (203) 41) Insulin secretion Middle cerebral artery Galanin; Pancreatic islets (Gregersen, S. (203) 111) Prostaglandin F,,,; Cerebral blood flow; Ca**-free medium; Ca** entry blockers (Salom, J.B. (203) 33) Intrapulmonary artery rings (sheep) Hypoxia; Flurbiprofen; Verapamil (Demiryurek, A.T. (203) 1) Miniature end-plate potential—fluoride Transmitter release; G-proteins; Protein kinase C (Light, P.E. (203) Ischaemia 311) Endothelin-1; Cerebral blood flow; Ischaemic pressor response MK 801 (Macrae, I. (203) 85) NMDA (N-methyl-D-aspartate); Phencyclidine (PCP); CPP (3-(2- carboxypiperazin-4-yl)-propyl-l-phosphonic acid); CGS 19755; 5- Ischaemic pressor response HT,, receptors; Tail flicks (spontaneous) (Millan, M.J. (203) 315) Endothelin-!; Cerebral blood flow; Ischaemia (Macrae, I. (203) 85) Morphine Ischemia Butorphanol; Withdrawal (precipitated and abrupt); Physical depen- Angiotensin I; Angiotensin Il; Angiotensin-converting enzyme dence (Horan, P. (203) 387) (cardiac); Heart (isolated); Coronary flow; Hypoxia (Tian, R. (203) 71) Morphine withdrawal Spinal morphine; Physical dependence; [Met°Jenkephalin levels Isethionate (Cridland, R.A. (203) 93) Smooth muscle (vascular); Cl~ ions; Ca** movement; Anion ex change inhibitors; Cl~ channels; Caffeine (Zhang, A. (203) 223) Muscarinic M, heteroreceptors (prejunctional) Muscarinic receptor agonists; Vas deferens (rabbit); Ca**; Piren- Isoflurane zepine; 4-Cl-McN-A-343 (Dorje, F. (203) 417) Anaesthetics (volatile); Halothane; Arachidonic acid cascade; G-pro- teins; Myocardial contractility; (Rat) (Vulliemoz, Y. (203) 345) Muscarinic receptor agonists Muscarinic M, heteroreceptors (prejunctional); Vas deferens (rabbit); Ketamine Ca**; Pirenzepine; 4-Cl-McN-A-343 (Dérje, F. (203) 417) Halothane; Pentobarbitone; Urethane; Ether; Alphaxalone; Diiso propylphenol; Lignocaine; Ca** currents (axonal); Olfactory cortex Muscarinic receptors (McGivern, J. (203) 59) Tetrahydroaminoacridine; Muscarinic receptor subtypes; Allosteric antagonists; Brain; (Rat) (Kiefer-Day, J.S. (203) 421) Kidney NPY receptors; NPY Y, receptor agonists; NPY Y, receptor ago- Muscarinic receptor subtypes nists; Spleen; Nasal mucosa; Vasoconstriction; Vas deferens (Modin, Tetrahydroaminoacridine; Muscarinic receptors; Allosteric antago- A. (203) 165) nists; Brain; (Rat) (Kiefer-Day, J.S. (203) 421) LiCl Myenteric plexus cAMP; Adenylate cyclase; Myenteric plexus; LiCl-treated animals LiCl; cAMP; Adenylate cyclase; LiCl-treated animals (chronically); (chronically); Phosphodiesterase inhibitors; (Isolated organ bath) Phosphodiesterase inhibitors; (Isolated organ bath) (Marmol, F. (203) (Marmol, F. (203) 181) 181) LiCl-treated animals (chronically) Myocardial contractility LiCl; cAMP; Adenylate cyclase; Myenteric plexus; Phosphodi- Anaesthetics (volatile); Halothane; Isoflurane; Arachidonic acid cas- esterase inhibitors; (Isolated organ bath) (Marmol, F. (203) 181) cade; G-proteins; (Rat) (Vulliemoz, Y. (203) 345)

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European Journal of Pharmacology 1991: Vol 203 Index PDF

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Preview European Journal of Pharmacology 1991: Vol 203 Index

European Journal of Pharmacology, 203 (1991) 425-428 © 1991 Elsevier Science Publishers B.V. All rights reserved 0014-2999 /91 $03.50 Author index Adachi, H., see Kawamura, T. (203) 399 Chugh, Y., Saha, N., Sankaranarayanan, A. and Sharma, P.L Ahrén, B., see Gregersen, S. (203) 111 Memory enhancing effects of granisetron (BRL 43694) in a Alabadi, J.A., see Salom, J.B. (203) 33 passive avoidance task (203) 121 Alborch, E., see Salom, J.B. (203) 33 Conforti, L., see Tohse, N. (203) 307 Alper, R.H., see Pérgola, P.E. (203) 145 Costa, G., see Garcia-Pascual, A. (203) 259 Altura, B.M., see Zhang, A. (203) 223 Costentin, J., see Bousselmame, R. (203) 295 Altura, B.T., see Zhang, A. (203) 223 Cowan, A., see Liu-Chen, L.-Y. (203) 195 Alvarez, C., see Salom, J.B. (203) 33 Coy, D.H., see Zacharia, S. (203) 353 Amir, S. and English, A.M. Cridland, R.A., Sutak, M. and Jhamandas, K. An inhibitor of nitric oxide production, N“-nitro-L-arginine- Characteristics of precipitated withdrawal from spinal morphine methyl ester, improves survival in anaphylactic shock (203) 125 changes in [Met*]Jenkephalin levels (203) 93 BackhauB, C., see Prehn, J.H.M. (203) 213 Dabiré, H., Bajjou, R., Chaouche-Teyara, K., Fournier, B., Bajjou, R., see Dabiré, H. (203) 323 De Nanteuil, G., Laubie, M., Safar, M. and Schmitt, H. Bang Olsen, U. and Lund, A. $14063: a new potent 5-HT,, receptor antagonist devoid of Inhibition by glutamate antagonists, MK-801 and NBOX, of B-adrenoceptor blocking properties (203) 323 cutaneo-cardiovascular pain reflex in rats (203) 133 DeHaven-Hudkins, D.L., Hildebrand, L.M., Fleissner, L.C. and Bao, J.-X., Gonon, F. and Stjarne, L Ward, SJ Electrochemical and electrophysiological analysis of the effects of Lack of correlation between o binding potency and inhibition of SK&F 104078 on prejunctional a,-adrenoceptors (203) 159 contractions in the mouse vas deferens preparation (203) 329 Barbanti, G., see Giuliani, S. (203) 365 De Jongste, J., see Jongejan, R. (203) 187 Barr, A.J., Watson, S.P., Bernal, A.L. and Nimmo, A.J. Delay-Goyet, P. and Lundberg, J.M. The presence of NK , tachykinin receptors on rat uterus (203) 287 Cigarette smoke-induced airway oedema is blocked by the NK, Bartfai, T., see Gregersen, S. (203) 111 antagonist, CP-96,345 (203) 157 Bataille, D., see Carles-Bonnet, C. (203) 245 Della Bella, D., see Sala, R. (203) 17 Bernal, A.L., see Barr, A.J. (203) 287 Demiryurek, A.T., Wadsworth, R.M. and Kane, K.A Bielen, F.V., see Verdonck, F. (203) 371 Pharmacological evidence for the role of mediators in hypoxia-in- Bitran, M., Torres, G., Fournier, A., St Pierre, S. and Huidobro-Toro, duced vasoconstriction in sheep isolated intrapulmonary artery J.P rings (203) 1 Age and castration modulate the inhibitory action of neuropep- De Montis, G., see Devoto, P. (203) 67 tide Y on neurotransmission in the rat vas deferens (203) 267 De Nanteuil, G., see Dabiré, H. (203) 323 Black, C.K., see Schmidt, C.J. (203) 41 Desaulles, E., Boux, O. and Feltz, P. Boje, K., see Trullas, R. (203) 379 Caffeine-induced Ca?* release inhibits GABA, responsiveness Bonta, I., see Jongejan, R. (203) 187 in rat identified native primary afferents (203) 137 Borsini, F., Cesana, R., Vidi, A. and Mennini, T. De Souza, E.B., see Sharpe, L.G. (203) 141 Evidence that imipramine activates 5-HT,. receptor function Devoto, P., Pani, L.. Kuzmin, A. and De Montis, G. (203) 359 Inhibition of [>H]dopamine uptake by flunarizine (203) 67 Bourguignon, J.-J., see Schmidt, C. (203) 393 Donetti, A., see Turconi, M. (203) 203 Bousselmame, R., Michael-Titus, A. and Costentin, J. Dorje, F., Rettenmayr, N.M., Mutschler, E. and Lambrecht, G Desensitization of 4-opioid receptors does not modify the anal- Effect of extracellular calcium concentration on potency of mus- gesia induced by an enkephalinase inhibitor (203) 295 carinic agonists at M, and M, receptors in rabbit vas deferens Boux, O., see Desaulles, E. (203) 137 (203) 417 Bruning, J.W., see Van Furth, W.R. (203) 413 Duff, HJ., see Hill, R.J. (203) 51 Campbell, H.E., see Kiefer-Day, J.S. (203) 421 El-Fakahany, E.E., see Kiefer-Day, J.S. (203) 421 Canton, H., see Millan, M.J. (203) 319 Endo, T., see Ninomiya, H. (203) 299 Carella, A., see Zhang, A. (203) 223 English, A.M., see Amir, S. (203) 125 Carenzi, A., see Sala, R. (203) 17 Ertan, A., see Zacharia, S. (203) 353 Carles-Bonnet, C., Jarrousse, C., Niel, H., Martinez, J. and Bataille, Ertl, G., see Tian, R. (203) 71 D Oxyntomodulin and its (19-37) and (30-37) fragments inhibit Feltz, P., see Desaulles, E. (203) 137 histamine-stimulated gastric acid secretion in the conscious rat Fisone, G., see Gregersen, S. (203) 111 (203) 245 Fleissner, L.C., see DeHaven-Hudkins, D.L. (203) 329 Cesana, R., see Borsini, F. (203) 359 Folio, T., see Trullas, R. (203) 379 Cesana, R., see Turconi, M. (203) 203 Forn, J., see Marmol, F. (203) 181 Chaouche-Teyara, K., see Dabiré, H. (203) 323 Fournier, A., see Bitran, M. (203) 267 426 Fournier, B., see Dabiré, H. (203) 323 Jarrousse, C., see Carles-Bonnet, C. (203) 245 Frambes, N.A., see Spear, L.P. (203) 9 Jhamandas, K., see Cridland, R.A. (203) 93 Fukuda, H., see Ono, H. (203) 283 Jiang, N.-Y., see Zacharia, S. (203) 353 Fukuda, N., see Hashimoto, T. (203) 25 Jino, H., see Shibata, S. (203) 337 Fukushima, R., see Yoshida, Y. (203) 173 Jones, D.J., see Shibata, S. (203) 337 Jongejan, R., De Jongste, J., Raatgeep, R., Stijnen, T., Bonta, |. and Kerrebijn, K Galagan, M.E., Mordvintcev, P.I. and Vanin, A.F Effect of epithelial denudation, inflammatory mediators and mast Effect of riboflavin on hypotensive activity of dinitrosyl iron cell activation on the sensitivity of isolated human airways to complex with thiosulphate (203) 325 methacholine (203) 187 Gandhi, V., see Shibata, S. (203) 337 Garcia-Pascual, A., Costa, G., Isla, M. and Garcia-Sacristan, A Characterization of a-adrenoceptors in the preprostatic urethra of sexually immature male lambs (203) 259 Kamei, J., Mori, T., Igarashi, H. and Kasuya, Y Garcia-Sacristan, A., see Garcia-Pascual, A. (203) 259 Effects of 8-hydroxy-2-(di-n-propylamino)tetralin, a selective ago- Giachetti, A., see Giuliani, S. (203) 365 nist of 5-HT,, receptors, on the cough reflex in rats (203) 253 Giuliani, S., Barbanti, G., Turini, D., Quartara, L., Rovero, P., Kamei, J., Tanihara, H. and Kasuya, Y Giachetti, A. and Maggi, C.A Modulation of yu-mediated antitussive activity in rats by a 6 NK, tachykinin receptors and contraction of circular muscle of agonist (203) 153 the human colon: characterization of the NK, receptor subtype Kameyama, M., see Ninomiya, H. (203) 299 (203) 365 Kane, K.A., see Demiryurek, A.T. (203) 1 Gobaille, S., see Schmidt, C. (203) 393 Karkoutly, C., see Prehn, J.H.M. (203) 213 Gonon, F., see Bao, J.-X. (203) 159 Kasuya, Y., see Kamei, J. (203) 153 Goodwin, G., see Spear, L.P. (203) 9 Kasuya, Y., see Kamei, J. (203) 253 Gregersen, S., Hermansen, K., Langel, U , Fisone, G., Bartfai, T Kawamura, T., Adachi, H. and Ogawa, T and Ahrén, B. Cardiovascular effects of E4080, a novel bradycardiac agent with Galanin-induced inhibition of insulin secretion from rat islets coronary vasodilating properties, in anesthetized dogs (203) 399 effects of rat and pig galanin and galanin fragments and ana- Kerrebijn, K., see Jongejan, R. (203) 187 logues (203) 111 Kiefer-Day, J.S., Campbell, H.E., Towles, J. and El-Fakahany, E.E Gunn, L.K. and Piper, P.J Muscarinic subtype selectivity of tetrahydroaminoacridine: possi- Potential sources of artefact in the co-axial bioassay (203) 405 ble relationship to its capricious efficacy (203) 421 Kizu, A., see Yoshida, Y. (203) 173 Haas, U., see Tian, R. (203) 71 Kodama, I., see Shibata, S. (203) 337 Hamdi, A. and Kostrzewa, R.M Kostrzewa, R.M., see Hamdi, A. (203) 115 Ontogenic homologous supersensitization of dopamine D, recep- Kozikowski, A.P., see McKinney, M. (203) 303 tors (203) 115 Krieglistein, J., see Prehn, J.H.M. (203) 213 Hasegawa, S., see Ninomiya, H. (203) 299 Kuzmin, A., see Devoto, P. (203) 67 Hashimoto, T. and Fukuda, N Effect of thyrotropin-releasing hormone on the neurologic im- pairment in rats with spinal cord injury: treatment starting 24 h Lambert, N.A. and Teyler, T.J and 7 days after injury (203) 25 Cholinergic disinhibition in area CA1 of the rat hippocampus is Hechler, V., see Schmidt, C. (203) 393 not mediated by receptors located on inhibitory neurons (203) Hermansen, K., see Gregersen, S. (203) 111 129 Hester, R.K., see Shibata, S. (203) 337 Lambrecht, G., see Dérje, F. (203) 417 Hildebrand, L.M., see DeHaven-Hudkins, D.L. (203) 329 Langel, U., see Gregersen, S. (203) 111 Hill, R.J., Thakore, E., Taouis, M., Duff, H.J. and Sheldon, R.S Laubie, M., see Dabiré, H. (203) 323 Transcainide: biochemical evidence for state-dependent interac- Laubie, M., see Millan, M.J. (203) 319 tion with the class I antiarrhythmic drug receptor (203) 51 Lavielle, G., see Millan, M.J. (203) 319 Hisa, H., see Takagi, H. (203) 291 Leander, J.D., see Schoepp, D.D. (203) 237 Ho, I.K., see Horan, P. (203) 387 Lejeune, F., see Millan, M.J. (203) 319 Hojo, M., see Shibata, S. (203) 337 Lewis, $.J., Machado, B.H., Ohta, H. and Talman, W.T. Homma, I., see Inazu, M. (203) 79 Processing of cardiopulmonary afferent input within the nucleus Horan, P. and Ho, I.K. tractus solitarii involves activation of soluble guanylate cyclase The physical dependence liability of butorphanol: a comparative (203) 327 study with morphine (203) 387 Li, S., see Liu-Chen, L.-Y. (203) 195 Hrbas, P., see Zacharia, S. (203) 353 Light, P.E. and Publicover, S.J. Huidobro-Toro, J.P., see Bitran, M. (203) 267 Stimulation of miniature end-plate potential frequency by fluo- ride may involve activation of protein kinase C (203) 311 Igarashi, H., see Kamei, J. (203) 253 Liu-Chen, L.-Y., Li, S., Wheeler-Aceto, H. and Cowan, A Inazu, M., Sakai, Y. and Homma, | Effects of intracerebroventricular B-funaltrexamine on yu and 6 Contractile responses and calcium mobilization in renal arteries opioid receptors in the rat: dichotomy between binding and of diabetic rats (203) 79 antinociception (203) 195 Insel, T.R. and Winslow, J.T. Lodge, D., see Schoepp, D.D. (203) 237 Central administration of oxytocin modulates the infant rat's Lund, A., see Bang Olsen, U. (203) 133 response to social isolation (203) 149 Lundberg, J.M., see Delay-Goyet, P. (203) 157 Ishii, Y., see Ninomiya, H. (203) 299 Lundberg, J.M., see Modin, A. (203) 165 Isla, M., see Garcia-Pascual, A. (203) 259 Lunn, W.H.W., see Schoepp, D.D. (203) 237 Machado, B.H., see Lewis, $.J. (203) 327 Pani, L., see Devoto, P. (203) 67 Macrae, I., Robinson, M., McAuley, M., Reid, J. and McCulloch, J Pérgola, P.E. and Alper, R.H. Effects of intracisternal endothelin-1 injection on blood flow to Pharmacological evidence that circumventricular organs may par- the lower brain stem (203) 85 ticipate in the pressor effect of central serotonin (203) 145 Maggi, C.A., see Giuliani, S. (203) 365 Pernow, J., see Modin, A. (203) 165 Maitre, M., see Schmidt, C. (203) 393 Peruche, B., see Prehn, J.H.M. (203) 213 Marmol, F., Puig-Parellada, P. and Forn, J Pilotte, N.S., see Sharpe, L.G. (203) 141 Chronic treatment of guinea pigs with lithium chloride: effects on Piper, P.J., see Gunn, L.K. (203) 405 myenteric plexus preparations and on cyclic AMP levels (203) 181 Prehn, J.H.M., BackhauB, C., Karkoutly, C., Nuglisch, J., Peruche, Martinez, J., see Carles-Bonnet, C. (203) 245 B., RoBberg, C. and Krieglstein, J. McAuley, M., see Macrae, I. (203) 85 Neuroprotective properties of 5-HT,, receptor agonists in rodent McCulloch, J., see Macrae, I. (203) 85 models of focal and global cerebral ischemia (203) 213 McGivern, J. and Scholfield, C.N Publicover, S.J., see Light, P.E. (203) 311 Action of general anaesthetics on unclamped Ca**-mediated Puig-Parellada, P., see Marmol, F. (203) 181 currents in unmyelinated axons of rat olfactory cortex (203) 59 Pulzer, F., see Tian, R. (203) 71 McKinney, M., Miller, J.H.. Yamada, F., Tuckmantel, W. and Kozikowski, A.P Quartara, L., see Giuliani, S. (203) 365 Potencies and stereoselectivities of enantiomers of huperzine A Raatgeep, R., see Jongejan, R. (203) 187 for inhibition of rat cortical acetylcholinesterase (203) 303 Reid, J., see Macrae, I. (203) 85 Mennini, T., see Borsini, F. (203) 359 Rettenmayr, N.M., see Dorje, F. (203) 417 Michael-Titus, A., see Bousselmame, R. (203) 295 Rivet, J.-M., see Millan, M.J. (203) 319 Micheletti, R., see Turconi, M. (203) 203 Rizzi, C., see Turconi, M. (203) 203 Millan, M.J., Canton, H., Rivet, J.-M., Lejeune, F., Laubie, M. and Robinson, M., see Macrae, 1. (203) 85 Lavielle, G RoBberg, C., see Prehn, J.H.M. (203) 213 S 14671: A novel naphthylpiperazine 5-HT,, agonist of high Rossuwski, W_J., see Zacharia, S$. (203) 353 efficacy and exceptional in vivo potency (203) 319 Rovero, P., see Giuliani, S. (203) 365 Millan, MJ Antagonists at the NMDA recognition site and blockers of the Sacaan, A.I., see Schoepp, D.D. (203) 237 associated ion channel induce spontaneous tail-flicks in the rat Safar, M., see Dabiré, H. (203) 323 (203) 315 Sagrada, A., see Turconi, M. (203) 203 Millar, J.D., see Schoepp, D.D. (203) 237 Saha, N., see Chugh, Y. (203) 121 Miller, J.H., see McKinney, M. (203) 303 Sakai, Y., see Inazu, M. (203) 79 Miller, R., see Trullas, R. (203) 379 Sala, R., Moriggi, E., Della Bella, D. and Carenzi, A. Miranda, F.J., see Salom, J.B. (203) 33 The specific binding of broxaterol, a new B,-selective agonist, to Mitchell, W.M., see Sharpe, L.G. (203) 141 B-adrenoceptors (203) 17 Miyagishi, T., see Yoshida, Y. (203) 173 Salom, J.B., Torregrosa, G., Miranda, F.J., Alabadi, J.A., Alvarez, C Modin, A., Pernow, J. and Lundberg, J.M and Alborch, E Evidence for two neuropeptide Y receptors mediating vasocon Ca** entry blockers inhibit prostaglandin F,,-induced cere- striction (203) 165 brovascular contractile responses in goats (203) 33 Montagna, E., see Turconi, M. (203) 203 Sankaranarayanan, A., see Chugh, Y. (203) 121 Mordvintcev, P.I., see Galagan, M.E. (203) 325 Saotome, M., see Ninomiya, H. (203) 299 Mori, T., see Kamei, J. (203) 253 Satake, N., see Shibata, S. (203) 337 Moriggi, E., see Sala, R. (203) 17 Satoh, S., see Takagi, H. (203) 291 Morris, J.L. Schaus, J.M., see Seeman, P. (203) 105 Pertussis toxin attenuates postsynaptic actions of neuropeptide Y Schiavone, A., see Turconi, M. (203) 203 on the guinea-pig uterine artery (203) 275 Schmidt, C., Gobaille, S., Hechler, V., Schmitt, M., Bourguignon Mutschler, E., see Dorje, F. (203) 417 J.-J. and Maitre, M. Anti-sedative and anti-cataleptic properties of NCS-382, a y-hy- Neubauer, S., see Tian, R. (203) 71 droxybutyrate receptor antagonist (203) 393 Nicola, M., see Turconi, M. (203) 203 Schmidt, C.J., Black, C.K. and Taylor, V.L. Niel, H., see Carles-Bonnet, C. (203) 245 L-DOPA potentiation of the serotonergic deficits due to a single Nimmo, A.J., see Barr, A.J. (203) 287 administration of 3,4-methylenedioxymethamphetamine, p-chlo- roamphetamine or methamphetamine to rats (203) 41 Ninomiya, H., Uchida, Y., Ishii, Y., Nomura, A., Kameyama, M.., Schmitt, H., see Dabiré, H. (203) 323 Saotome, M., Endo, T. and Hasegawa, S Schmitt, M., see Schmidt, C. (203) 393 Endotoxin stimulates endothelin release from cultured epithelial Schoepp, D.D., Smith, C.L., Lodge, D., Millar, J.D., Leander, J.D., cells of guinea-pig trachea (203) 299 Sacaan, A.I. and Lunn, W.H.W Nomura, A., see Ninomiya, H. (203) 299 Nuglisch, J., see Prehn, J.H.M. (203) 213 D,L-4Tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist (203) 237 Scholfield, C.N., see McGivern, J. (203) 59 Ogawa, T., see Kawamura, T. (203) 399 Seeman, P. and Schaus, J.M. Ohta, H., see Lewis, S.J. (203) 327 Dopamine receptors labelled by [*H]quinpirole (203) 105 Ono, H., Ono, S.-S. and Fukuda, H Sharma, P.L., see Chugh, Y. (203) 121 5-HT receptor-mediated regulation of thyrotropin-releasing hor- Sharpe, L.G., Pilotte, N.S., Mitchell, W.M. and De Souza, E.B mone release in rat spinal cord (203) 283 Withdrawal of repeated cocaine decreases autoradiographic Ono, S.-S., see Ono, H. (203) 283 {*H]}mazindol-labelling of dopamine transporter in rat nucleus Ono, T., see Yoshida, Y. (203) 173 accumbens (203) 141 428 Sheldon, R.S., see Hill, R.J. (203) 51 Pharmacological properties of a novel class of 5-HT, receptor Shibata, S., Satake, N., Kodama, I., Hester, R.K., Wang, C.-G., Jino antagonists (203) 203 H., Hojo, M., Tatsumi, H., Gandhi, V. and Jones, DJ Turini, D., see Giuliani, S. (203) 365 Pharmacological characteristics of NP-252, a new dihydropyridine slow Ca** channel blocker, in isolated rabbit vascular smooth Uchida, Y., see Ninomiya, H. (203) 299 muscle and guinea pig myocardium: vascular selectivity (203) 337 Skolnick, P., see Trullas, R. (203) 379 Van Furth, W.R., Wiegant, V.M., Bruning, J.W. and Van Ree, J.M Smith, C.L., see Schoepp, D.D. (203) 237 The grasping response in rats: interaction between y-type endor- Spear, L.P., Frambes, N.A. and Goodwin, G phins and haloperidol (203) 413 Low doses of the 5-HT,, receptor agonist 8-OH-DPAT increase Vanin, A.F., see Galagan, M.E. (203) 325 ingestive behavior in late preweanling and postweanling, but not Van Ree, J.M., see Van Furth, W.R. (203) 413 neonatal rat pups (203) 9 Verdonck, F., Bielen, F.V. and Ver Donck, I Sperelakis, N., see Tohse, N. (203) 307 Preferential block of the veratridine-induced, non-inactivating Stijnen, T., see Jongejan, R. (203) 187 Na” current by R56865 in single cardiac Purkinje cells (203) 371 Stjarne, L., see Bao, J.-X. (203) 159 Ver Donck, L., see Verdonck, F. (203) 371 St Pierre, S., see Bitran, M. (203) 267 Vidi, A., see Borsini, F. (203) 359 Sutak, M., see Cridland, R.A. (203) 93 Vulliemoz, Y The myocardial depressant effect of volatile anesthetics does not Takagi, H., Hisa, H. and Satoh, S involve arachidonic acid metabolites or pertussis toxin-sensitive G Effects of endothelin on adrenergic neurotransmission in the dog proteins (203) 345 kidney (203) 291 alman, W.T., see Lewis, S.J. (203) 327 anihara, H., see Kamei, J. (203) 153 adsworth, R.M., see Demiryurek, A.T. (203) 1 aouis, M., see Hill, R.J. (203) 51 Wang, C.-G., see Shibata, S. (203) 337 atsumi, H., see Shibata, S. (203) 337 Ward, S.J., see DeHaven-Hudkins, D.L. (203) 329 Watson, S.P., see Barr, A.J. (203) 287 Taylor, V.L., see Schmidt, C.J. (203) 41 Teyler, T.J., see Lambert, N.A. (203) 129 Wheeler-Aceto, H., see Liu-Chen, L.-Y. (203) 195 Wiegant, V.M., see Van Furth, W.R. (203) 413 Thakore, E., see Hill, R.J. (203) 51 Tian, R., Neubauer, S., Pulzer, F., Haas, U. and Ertl, G Winslow, J.T., see Insel, T.R. (203) 149 Angiotensin I conversion and coronary constriction by an giotensin Il in ischemic and hypoxic isolated rat hearts (203) 71 Yamada, F., see McKinney, M. (203) 303 Tohse, N., Conforti, L. and Sperelakis, N Yoshida, Y., Ono, T., Kizu, A., Fukushima, R. and Miyagishi, T Bay K 8644 enhances Ca~* channel activities in embryonic chick Striatal N-methyl-D-aspartate receptors in haloperidol-induced heart cells without prolongation of open times (203) 307 catalepsy (203) 173 Torregrosa, G., see Salom, J.B. (203) 33 Young, A., see Trullas, R. (203) 379 Torres, G., see Bitran, M. (203) 267 Towles, J., see Kiefer-Day, J.S. (203) 421 Zacharia, S., Rossowski, W.J., Jiang, N.-Y., Hrbas, P., Ertan, A. and Trullas, R., Folio, T., Young, A., Miller, R., Boje, K. and Skolnick, P Coy, D.H 1-Aminocyclopropanecarboxylates exhibit antidepressant and New reduced peptide bond substance P agonists and antagonists anxiolytic actions in animal models (203) 379 effects on smooth muscle contraction (203) 353 Tuckmantel, W., see McKinney, M. (203) 303 Zhang, A., Carella, A., Altura, B.T. and Altura, B.M Turconi, M., Donetti, A., Schiavone, A., Sagrada, A., Montagna, E Interactions of magnesium and chloride ions on tone and con Nicola, M., Cesana, R., Rizzi, C. and Micheletti, R tractility of vascular muscle (203) 223 European Journal of Pharmacology, 203 (1991) 429-438 © 1991 Elsevier Science Publishers B.V. All rights reserved 0014-2999 /9] $03.50 Key word index Acetorphan Alphaxalone Desensitization; u-Opioid receptors; 5-Opioid receptors; Analgesia Halothane; Ketamine; Pentobarbitone; Urethane; Ether; Diisopro- (Bousselmame, R. (203) 295) pylphenol; Lignocaine; Ca** currents (axonal); Olfactory cortex (McGivern, J. (203) 59) Acetylcholine Cholinomimetics; Cerebral cortex; Stereochemistry; Alzheimer's dis Alzheimer’s disease ease; (Natural products) (McKinney, M. (203) 303) Acetylcholine; Cholinomimetics; Cerebral cortex; Stereochemistry; (Natural products) (McKinney, M. (203) 303) ACPC (1l-aminocyclopropanecarboxylic acid) NMDA (N-methyl-D-aspartate); Strychnine-insensitive glycine re cAMP ceptors; Plus-maze; Forced swimming test (Trullas, R. (203) 379) LiCl; Adenylate cyclase; Myenteric plexus; LiCl-treated animals (chronically), Phosphodiesterase inhibitors; (Isolated organ bath) A-delta afferents (Marmol, F. (203) 181) GABA , receptors; Ca Sensory neurones; Ca pools (intracellu AMPA receptors lar); Caffeine; Ryanodine (Desaulles, E. (203) 137) NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo( F quinoxaline) ; Pain reflex; (Rat) (Bang Olsen, U. (203) 133) Adenylate cyclase LiCl; cAMP; Myenteric plexus; LiCl-treated animals (chronically) Anaesthetics (volatile) Phosphodiesterase inhibitors; (Isolated organ bath) (Marmol, F. (203) Halothane; Isoflurane; Arachidonic acid cascade; G-proteins; My 181) ocardial contractility; (Rat) (Vulliemoz, Y. (203) 345) Adrenoceptors Analgesia Urethra; (Lamb) (Garcia-Pascual, A. (203) 259) Desensitization; p-Opioid receptors; 5-Opioid receptors; Acetor phan (Bousselmame, R. (203) 295) a@,-Adrenoceptors (prejunctional) ATP: Electrochemistry; Noradrenaline (endogenous), Extracellular Anaphylactic shock recording; SK&F 104078 (Bao, J.-X. (203) 159) Nitric oxide (NO); L-NAME (N“-nitro-L-arginine methyl ester) (Mouse) (Amir, S. (203) 125) B-Adrenoceptors B,-Adrenoceptor-selective agonists; Broxaterol; Thermodynamics; Angiotensin | Enthalpy changes; Entropy changes (Sala, R. (203) 17) Angiotensin Il; Angiotensin-converting enzyme (cardiac); Heart (iso lated), Coronary flow; Ischemia; Hypoxia (Tian, R. (203) 71) B,-Adrenoceptor-selective agonists B-Adrenoceptors; Broxaterol; Thermodynamics; Enthalpy changes Angiotensin Il Entropy changes (Sala, R. (203) 17) Angiotensin I; Angiotensin-converting enzyme (cardiac), Heart (iso lated), Coronary flow; Ischemia; Hypoxia (Tian, R. (203) 71) Affiliation Oxytocin; Ultrasonic vocalization; Anxiety; Thermoregulation (Insel Angiotensin-converting enzyme (cardiac) Angiotensin I; Angiotensin II; Heart (isolated); Coronary flow; Is T.R. (203) 149) chemia; Hypoxia (Tian, R. (203) 71) Airway Anion exchange inhibitors Co-axial bioassay; EpDRF (epithelium-derived relaxant factor), Tra chea (guinea-pig); Bronchus (rabbit); Aorta (rat) (Gunn, L.K. (203) Smooth muscle (vascular), Cl ions; Isethionate;: Ca movement Cl” channels; Caffeine (Zhang, A. (203) 223) 405) Antianginal agent Airway epithelial cells E4080; Bradycardiac agents; Coronary vasodilating action; ATP-sen Endothelin; Endotoxin (Ninomiya, H. (203) 299) sitive K* channels; Glibenclamide (Kawamura, T. (203) 399) Airway muscle (human) Antiarrhythmic drugs Bronchial hyperresponsiveness; Inflammatory mediators; Epithe Batrachotoxinin; Na*~ channels; State-dependent binding (Hill, RJ lium; Mast cell activation; Anti-human immunoglobulin E Jongejan (203) 51) R. (203) 187) Anti-human immunoglobulin E Allosteric antagonists Airway muscle (human); Bronchial hyperresponsiveness; Inflamma Tetrahydroaminoacridine; Muscarinic receptors; Muscarinic receptor tory mediators; Epithelium; Mast cell activation (Jongejan, R. (203) subtypes; Brain; (Rat) (Kiefer-Day, J.S. (203) 421) 187) 430 Antinociception Bronchial hyperresponsiveness B-Funaltrexamine; Opioid receptor binding (Liu-Chen, L.-Y. (203) Airway muscle (human); Inflammatory mediators; Epithelium; Mast 195) cell activation; Anti-human immunoglobulin E (JJongejan, R. (203) 187) Antitussive effects p-Opioid receptors; 5-Opioid receptors; Cough reflex; Naltrindole; Bronchus (rabbit) (Rat) (Kamei, J. (203) 153) Co-axial bioassay; EpDRF (epithelium-derived relaxant factor); Air- way; Trachea (guinea-pig); Aorta (rat) (Gunn, L.K. (203) 405) Antitussives Cough reflex; 5-HT receptors; 8-OH-DPAT (8-hydroxy-2-(di-n-pro Broxaterol pylamino)tetralin); 5-HT,, receptors (Kamei, J. (203) 253) B-Adrenoceptors; 8,-Adrenoceptor-selective agonists; Thermody- namics; Enthalpy changes; Entropy changes (Sala, R. (203) 17) Anxiety Oxytocin; Ultrasonic vocalization; Thermoregulation; Affiliation (In Butorphanol sel, T.R. (203) 149) Morphine; Withdrawal (precipitated and abrupt), Physical depen- dence (Horan, P. (203) 387) Aorta (rat) Co-axial bioassay; EpDRF (epithelium-derived relaxant factor); Air Ca. * 2+ way; Trachea (guinea-pig); Bronchus (rabbit) (Gunn, L.K. (203) 405) GABA, receptors; Sensory neurones; Ca~* pools (intracellular), Caffeine; Ryanodine; A-delta afferents (Desaulles, E. (203) 137) Arachidonic acid cascade Anaesthetics (volatile); Halothane; Isoflurane; G-proteins; Myocar Muscarinic M, heteroreceptors (prejunctional); Muscarinic receptor dial contractility; (Rat) (Vulliemoz, Y. (203) 345) agonists; Vas deferens (rabbit); Pirenzepine; 4-Cl-McN-A-343 (Dorje, F. (203) 417) ATP Electrochemistry; Noradrenaline (endogenous); Extracellular record Ca** binding ing; a@»-Adrenoceptors (prejunctional); SK&F 104078 (Bao, J.-X Ca~* channel blockers; Smooth muscle (vascular); Cardiac muscle; (203) 159) Ca* uptake; Tissue selectivity; (Slow response) (Shibata, S. (203) 337) ATP-sensitive K * channels Ca** channel agonists E4080; Bradycardiac agents; Coronary vasodilating action; Gliben Heart cells (cultured); Heart cells (embryonic); Patch clamp analysis; clamide; Antianginal agent (Kawamura, T. (203) 399) Ca-~ channels (L-type); Single channel currents (Tohse, N. (203) 307) Baclofen Carbachol; Inhibitory postsynaptic potentials (monosynaptic); Phor Ca** channel antagonists bol esters; (Disinhibition) (Lambert, N.A. (203) 129) Cocaine; Dopamine uptake; Striatal synaptosomes (Devoto, P. (203) 67) Batrachotoxinin Antiarrhythmic drugs; Na“ channels; State-dependent binding (Hill, Ca** channel blockers R.J. (203) 51) Smooth muscle (vascular); Cardiac muscle; Ca** uptake; Tissue selec- tivity; Ca~* binding; (Slow response) (Shibata, S. (203) 337) Benzimidazolone derivatives 5-HT, receptors; 5-HT, receptors; Prokinetic activity (Turconi, M Ca** channels (203) 203) Diabetes; Renal artery; Hyperreactivity; Hyperpermeability (Inazu, M. (203) 79) Blood pressure 5-HT (5-hydroxytryptamine, serotonin); Circumventricular organs; Ca?* channels (L-type) Xylamidine; (Conscious rat) (Pérgola, P.E. (203) 145) Heart cells (cultured); Heart cells (embryonic); Patch clamp analysis; Single channel currents; Ca** channel agonists (Tohse, N. (203) 307) Bradycardiac agents E4080; Coronary vasodilating action; ATP-sensitive K* channels; Ca** currents (axonal) Glibenclamide; Antianginal agent (Kawamura, T. (203) 399) Halothane; Ketamine; Pentobarbitone; Urethane; Ether; Alphax- alone; Diisopropylphenol; Lignocaine; Olfactory cortex (McGivern, Brain J. (203) 59) Tetrahydroaminoacridine; Muscarinic receptors; Muscarinic receptor subtypes; Allosteric antagonists; (Rat) (Kiefer-Day, J.S. (203) 421) Ca** entry blockers Prostaglandin F,,; Cerebral blood flow; Middle cerebral artery; Brain (guinea-pig) Ca**-free medium (Salom, J.B. (203) 33) o Receptors; Vas deferens (mouse); Twitch contractions (electrically stimulated) (DeHaven-Hudkins, D.L. (203) 329) Caffeine GABA , receptors; Ca**; Sensory neurones; Ca?* pools (intracellu- Brain (rat) lar); Ryanodine; A-delta afferents (Desaulles, E. (203) 137) y-Hydroxybutyrate receptors; y-Hydroxybutyrate receptor antago- nists; Sedative /anaesthetic effects; NCS-382; Catalepsy; Neurolep- Smooth muscle (vascular); Cl~ ions; Isethionate: Ca** movement: tics (Schmidt, C. (203) 393) Anion exchange inhibitors; Cl~ channels (Zhang, A. (203) 223) Ca**-free medium p-Chloroamphetamine Prostaglandin F,,; Cerebral blood flow; Middle cerebral artery; MDMA(3,4-methylenedioxymethamphetamine); Methamphetamine; Ca** entry blockers (Salom, J.B. (203) 33) Fenfluramine; Dopamine/serotonin neurotoxicity (Schmidt, C.J. (203) 41) Ca** movement Smooth muscle (vascular); Cl” ions; Isethionate; Anion exchange Cholinomimetics inhibitors; Cl” channels; Caffeine (Zhang, A. (203) 223) Acetylcholine; Cerebral cortex; Stereochemistry; Alzheimer’s dis- ease; (Natural products) (McKinney, M. (203) 303) Ca’** pools (intracellular) GABA, receptors; Ca**: Sensory neurones; Caffeine; Ryanodine; Circumventricular organs A-delta afferents (Desaulles, E. (203) 137) 5-HT (5-hydroxytryptamine, serotonin); Blood pressure; Xylamidine; (Conscious rat) (Pérgola, P.E. (203). 145) Carbachol Baclofen; Inhibitory postsynaptic potentials (monosynaptic), Phorbol Cl” channels esters; (Disinhibition) (Lambert, N.A. (203) 129) Smooth muscle (vascular); Cl~ ions; Isethionate; Ca?* movement; Anion exchange inhibitors; Caffeine (Zhang, A. (203) 223) Cardiac cells Na” currents; Veratridine; Cardioprotection; (Block) (Verdonck, F (203) 371) Cl” ions Smooth muscle (vascular); Isethionate; Ca2* movement; Anion ex- Cardiac muscle change inhibitors; Cl” channels; Caffeine (Zhang, A. (203) 223) Ca** channel blockers; Smooth muscle (vascular); Ca** uptake; Tis- sue selectivity; Ca?* binding; (Slow response) (Shibata, S. (203) 337) 4-Cl-McN-A-343 Muscarinic M, heteroreceptors (prejunctional); Muscarinic receptor Cardioprotection agonists; Vas deferens (rabbit); Ca?*; Pirenzepine (Dérje, F. (203) Na~ currents; Veratridine; Cardiac cells; (Block) (Verdonck, F 417) (203) 371) Co-axial bioassay Castration /neurotransmission EpDRF (epithelium-derived relaxant factor); Airway; Trachea Neuropeptide Y (NPY); Vas deferens; Neurotransmission; Hor- (guinea-pig); Bronchus (rabbit); Aorta (rat) (Gunn, L.K. (203) 405) monal regulation; (Age and castration); (Rat) (Bitran, M. (203) 267) Cocaine Catalepsy Ca** channel antagonists; Dopamine uptake; Striatal synaptosomes Haloperidol; NMDA receptors; Dopamine; Glutamate; Caudate- (Devoto, P. (203) 67) putamen; (Rat) (Yoshida, Y. (203) 173) Colon (human) y-Hydroxybutyrate receptors; y-Hydroxybutyrate receptor antago- Tachykinins; Tachykinin receptors; Tachykinin receptor antagonists; nists; Sedative /anaesthetic effects; Brain (rat); NCS-382; Neurolep- NK, receptor subtypes (Giuliani, S. (203) 365) tics (Schmidt, C. (203) 393) Caudate-putamen Convulsions Catalepsy; Haloperidol; NMDA receptors; Dopamine; Glutamate; NMDA (N-methyl-D-aspartate); Excitatory amino acids (Schoepp, (Rat) (Yoshida, Y. (203) 173) D.D. (203) 237) Ca* uptake Coronary flow Ca** channel blockers; Smooth muscle (vascular); Cardiac muscle; Angiotensin 1; Angiotensin II; Angiotensin-converting enzyme Tissue selectivity; Ca** binding; (Slow response) (Shibata, S. (203) (cardiac), Heart (isolated), Ischemia; Hypoxia (Tian, R. (203) 71) 337) Coronary vasodilating action Cerebral blood flow E4080; Bradycardiac agents; ATP-sensitive K* channels; Gliben- Prostaglandin F,,,; Middle cerebral artery; Ca? *-free medium; Ca?* clamide; Antianginal agent (Kawamura, T. (203) 399) entry blockers (Salom, J.B. (203) 33) Cough reflex Endothelin-1; Ischaemia; Ischaemic pressor response (Macrae, | p-Opioid receptors; 5-Opioid receptors; Antitussive effects; Nal- (203) 85) trindole; (Rat) (Kamei, J. (203) 153) Cerebral cortex Antitussives; 5-HT receptors; 8-OH-DPAT (8-hydroxy-2-(di-n-pro- Acetylcholine; Cholinomimetics; Stereochemistry; Alzheimer’s dis- pylamino)tetralin), 5-HT,, receptors (Kamei, J. (203) 253) ease; (Natural products) (McKinney, M. (203) 303) Cerebral ischemia CPP (3-(2-carboxypiperazin-4-yl)-propyl-i-phosphonic acid) 5-HT,, receptor agonists; Neuroprotection; Hypothermia (Prehn, NMDA (N-methyl-D-aspartate); MK 801; Phencyclidine (PCP), CGS J.H.M. (203) 213) 19755; 5-HT,, receptors; Tail flicks (spontaneous) (Millan, MJ (203) 315) CGS 19755 NMDA (N-methyl-D-aspartate); MK 801; Phencyclidine (PCP); CPP Desensitization (3-(2-carboxypiperazin-4-yl)-propyl-l-phosphonic acid); 5-HT,, re- p-Opioid receptors; 5-Opioid receptors; Acetorphan; Analgesia ceptors; Tail flicks (spontaneous) (Millan, M.J. (203) 315) (Bousselmame, R. (203) 295) 432 Desipramine Endotoxin Forced swimming test; Imipramine; 5-HT receptor antagonists Endothelin; Airway epithelial cells (Ninomiya, H. (203) 299) (Mouse) (Borsini, F. (203) 359) [Met* Jenkephalin levels Diabetes Spinal morphine; Physical dependence; Morphine withdrawal (Crid- Renal artery; Ca channels; Hyperreactivity; Hyperpermeability land, R.A. (203) 93) (Inazu, M. (203) 79) Enthalpy changes Diisopropylphenol B-Adrenoceptors; £,-Adrenoceptor-selective agonists; Broxaterol; Halothane; Ketamine: Pentobarbitone; Urethane; Ether: Alphax Thermodynamics; Entropy changes (Sala, R. (203) 17) alone; Lignocaine; Ca currents (axonal); Olfactory cortex (Mc Givern, J. (203) 59) Entropy changes B-Adrenoceptors; £,-Adrenoceptor-selective agonists; Broxaterol; Dopamine Thermodynamics; Enthalpy changes (Sala, R. (203) 17) Dopamine receptors; Quinpirole; Striatum; Neuroleptics (Seeman, P. (203) 105) EpDRF (epithelium-derived relaxant factor) Co-axial bioassay; Airway; Trachea (guinea-pig); Bronchus (rabbit); Ontogeny; Dopamine D, receptors; 6-Hydroxydopamine (6-OHDA); Aorta (rat) (Gunn, L.K. (203) 405) SK&F 38393; Supersensitization (Hamdi, A. (203) 115) Epithelium Catalepsy; Haloperidol; NMDA receptors; Glutamate: Caudate Airway muscle (human); Bronchial hyperresponsiveness; Inflamma putamen; (Rat) (Yoshida, Y. (203) 173) tory mediators; Mast cell activation; Anti-human immunoglobulin (Jongejan, R. (203) 187) Dopamine receptors Dopamine; Quinpirole; Striatum; Neuroleptics (Seeman, P. (203) Ether 105) Halothane; Ketamine; Pentobarbitone; Urethane; Alphaxalone; Di- isopropylphenol; Lignocaine; Ca** currents (axonal); Olfactory cor Dopamine D, receptors tex (McGivern, J. (203) 59) Ontogeny; Dopamine; 6-Hydroxydopamine (6-OHDA),; SK&F 38393 Supersensitization (Hamdi, A. (203) 115) Excitatory amino acids NMDA (N-methyl-D-aspa:tate); Convulsions (Schoepp, D.D. (203) Dopamine/serotonin neurotoxicity 237) MDMA(3.4-methylenedioxymethamphetamine); p-Chloroampheta mine; Methamphetamine: Fenfluramine (Schmidt, C.J. (203) 41) Extracellular recording ATP; Electrochemistry; Noradrenaline (endogenous); a .,-Adreno- Dopamine uptake ceptors (prejunctional); SK&F 104078 (Bao, J.-X. (203) 159) Cocaine; Ca? channel antagonists; Striatal synaptosomes (Devoto, P. (203) 67) Fenfluramine MDMA(3,4-methylenedioxymethamphetamine);, p-Chloroampheta- Sensitization; Striatum; Down-regulation (Sharpe, L.G. (203) 141) mine; Methamphetamine; Dopamine/serotonin neurotoxicity (Schmidt, C.J. (203) 41) Down-regulation Sensitization; Striatum; Dopamine uptake (Sharpe, L.G. (203) 141) Flurbiprofen Duodenum (rat) Hypoxia; Intrapulmonary artery rings (sheep); Verapamil (De- Substance P; Substance P analogues (hepta- and hexapseudopeptide); miryurek, A.T. (203) 1) Spantide; NK, receptors; NK, receptors; Ileum (guinea-pig) (Zacharia, §. (203) 353) Forced swimming test Imipramine; Desipramine; 5-HT,,. receptor antagonists; (Mouse) E4080 (Borsini, F. (203) 359) Bradycardiac agents; Coronary vasodilating action; ATP-sensitive K* channels; Glibenclamide; Antianginal agent (Kawamura, T. (203) ACPC (l-aminocyclopropanecarboxylic acid); NMDA (N-methyl-D- 399) aspartate); Strychnine-insensitive glycine receptors; Plus-maze (Trul- las, R. (203) 379) Electrochemistry ATP; Noradrenaline (endogenous); Extracellular recording; a, 8 -Funaltrexamine Adrenoceptors (prejunctional); SK&F 104078 (Bao, J.-X. (203) 159) Opioid receptor binding; Antinociception (Liu-Chen, L.-Y. (203) 195) Endorphins (y -type) Haloperidol; Grasping response (Van Furth, W.R. (203) 413) GABA, receptors Ca**; Sensory neurones; Ca?” pools (intracellular); Caffeine; Ryan- Endothelin-1 odine; A-delta afferents (Desaulles, E. (203) 137) Cerebral blood flow; Ischaemia; Ischaemic pressor response (Mac- rae, 1. (203) 85) Galanin Pancreatic islets; Insulin secretion (Gregersen, S. (203) 111) Norepinephrine release; Renal blood flow; (Dog) (Takagi, H. (203) 291) Gastric acid secretion Histamine; Oxyntomodulin; Oxyntomodulin fragments; (Conscious Endotoxin; Airway epithelial cells (Ninomiya, H. (203) 299) rat) (Carles-Bonnet, C. (203) 245) Glibenclamide 5-HT,, receptor agonists E4080; Bradycardiac agents; Coronary vasodilating action; ATP-sen 5-HT,, autoreceptors; Ingestion; 8-OH-DPAT (8-hydroxy-2-4di-n- sitive K* channels; Antianginal agent (Kawamura, T. (203) 399) propylamino)tetralin); Ontogeny (Spear, L.P. (203) 9) Glutamate Cerebral ischemia; Neuroprotection; Hypothermia (Prehn, J.H.M Catalepsy; Haloperidol; NMDA receptors; Dopamine; Caudate (203) 213) putamen; (Rat) (Yoshida, Y. (203) 173) 5-HT, receptor antagonists G-proteins Memory; (Mouse) (Chugh, Y. (203) 121) Neuropeptide Y (NPY); VIP (vasoactive intestinal polypeptide); 5-HT,,. receptor antagonists Vasoconstriction; Pertussis toxin (Morris, J.L. (203) 275) Forced swimming test; Imipramine; Desipramine; (Mouse) (Borsini, Transmitter release; Miniature end-plate potential—fluoride; Protein F. (203) 359) kinase C (Light, P.E. (203) 311) 5-HT receptors Cough reflex; Antitussives; 8-OH-DPAT (8-hydroxy-2-di-n-pro- Anaesthetics (volatile); Halothane; Isoflurane; Arachidonic acid cas pylamino)tetralin), 5-HT,, receptors (Kamei, J. (203) 253) cade; Myocardial contractility; (Rat) (Vulliemoz, Y. (203) 345) 5-HT,, receptors Grasping response Cough reflex; Antitussives; 5-HT receptors; 8-OH-DPAT (8-hydroxy- Haloperidol; Endorphins (y-type) (Van Furth, W.R. (203) 413) 24di-n-propylamino)}tetralin) (Kamei, J. (203) 253) Haloperidol NMDA (N-methyl-D-aspartate); MK 801; Phencyclidine (PCP); CPP Catalepsy; NMDA receptors; Dopamine; Glutamate; Caudate-puta- (342-carboxypiperazin-4-yl)-propyl-l-phosphonic acid); CGS 19755; men; (Rat) (Yoshida, Y. (203) 173) Tail flicks (spontaneous) (Millan, M.J. (203) 315) Grasping response; Endorphins (y-type) (Van Furth, W.R. (203) 413) S 14671; 8-OH-DPAT (8-hydroxy-2-4di-n-propylamino)tetralin); Naphthylpiperazine; Tail flick (spontaneous) (Millan, M.J. (203) 319) Halothane Ketamine; Pentobarbitone; Urethane; Ether; Alphaxalone; Diiso- 5-HT, receptors propylphenol; Lignocaine; Ca** currents (axonal); Olfactory cortex 5-HT, receptors; Benzimidazolone derivatives; Prokinetic activity (McGivern, J. (203) 59) (Turconi, M. (203) 203) Anaesthetics (volatile); Isoflurane; Arachidonic acid cascade; G-pro- 5-HT, receptors teins; Myocardial contractility; (Rat) (Vulliemoz, Y. (203) 345) 5-HT, receptors; Benzimidazolone derivatives; Prokinetic activity (Turconi, M. (203) 203) Heart cells (cultured) Heart cells (embryonic); Patch clamp analysis; Ca** channels (1 y -Hydroxybutyrate receptor antagonists type); Single channel currents; Ca** channel agonists (Tohse, N y-Hydroxybutyrate receptors; Sedative /anaesthetic effects; Brain (203) 307) (rat); NCS-382; Catalepsy; Neuroleptics (Schmidt, C. (203) 393) Heart cells (embryonic) y -Hydroxybutyrate receptors y-Hydroxybutyrate receptor antagonists; Sedative /anaesthetic ef Heart cells (cultured); Patch clamp analysis; Ca** channels (1 -type); Single channel currents; Ca~~ channel agonists (Tohse, N. (203) 307) fects; Brain (rat); NCS-382; Catalepsy; Neuroleptics (Schmidt, C (203) 393) Heart (isolated) 6-Hydroxydopamine (6-OHDA) Angiotensin I; Angiotensin II; Angiotensin-converting enzyme Ontogeny; Dopamine; Dopamine D, receptors; SK&F 38393; Super- (cardiac); Coronary flow; Ischemia; Hypoxia (Tian, R. (203) 71) sensitization (Hamdi, A. (203) 115) Histamine Hyperpermeability Oxyntomodulin; Oxyntomodulin fragments; Gastric acid secretion; Diabetes; Renal artery; Ca** channels; Hyperreactivity (Inazu, M (Conscious rat) (Carles-Bonnet, C. (203) 245) (203) 79) Hormonal regulation Hyperreactivity Neuropeptide Y (NPY); Vas deferens; Neurotransmission; Castra- Diabetes; Renal artery; Ca** channels; Hyperpermeability (Inazu, tion /neurotransmission; (Age and castration); (Rat) (Bitran, M. (203) M. (203) 79) 267) Hypothermia 5-HT,, autoreceptors 5-HT,, receptor agonists; Cerebral ischemia; Neuroprotection 5-HT,, receptor agonists; Ingestion; 8-OH-DPAT (8-hydroxy-2-(di- (Prehn, J.H.M. (203) 213) n-propylamino)tetralin); Ontogeny (Spear, L.P. (203) 9) Hypoxia 5-HT (5-hydroxytryptamine, serotonin) Intrapulmonary artery rings (sheep); Flurbiprofen; Verapamil (De- Circumventricular organs; Blood pressure; Xylamidine; (Conscious miryurek, A.T. (203) 1) rat) (Pérgola, P.E. (203) 145) Angiotensin I; Angiotensin I]; Angiotensin-converting enzyme Thyrotropin-releasing hormone (TRH) release; Spinal cord (Ono, H (cardiac), Heart (isolated); Coronary flow; Ischemia (Tian, R. (203) (203) 283) 71) 434 lleum (guinea-pig) Lignocaine Substance P; Substance P analogues (hepta- and hexapseudopeptide); Halothane; Ketamine; Pentobarbitone; Urethane; Ether; Alphax- Spantide; NK, receptors; NK, receptors; Duodenum (rat) (Zacharia, alone; Diisopropylphenol; Ca? * currents (axonal); Olfactory cortex S. (203) 353) (McGivern, J. (203) 59) Imipramine Mast cell activation Forced swimming test; Desipramine; 5-HT,,. receptor antagonists; Airway muscle (human); Bronchial hyperresponsiveness; Inflamma- (Mouse) (Borsini, F. (203) 359) tory mediators; Epithelium; Anti-human immunoglobulin E (Jonge- jan, R. (203) 187) Inflammatory mediators Airway muscle (human); Bronchial hyperresponsiveness; Epithelium; MDMaA(3,4-methylenedioxymethamphetamine ) Mast cell activation; Anti-human immunoglobulin E (VJJongejan, R p-Chloroamphetamine; Methamphetamine; Fenfluramine; Dopa- (203) 187) mine /Serotonin neurotoxicity (Schmidt, C.J. (203) 41) Ingestion Memory 5-HT,, receptor agonists; 5-HT,, autoreceptors; 8-OH-DPAT (8 5-HT, receptor antagonists; (Mouse) (Chugh, Y. (203) 121) hydroxy-2-(di-n-propylamino)tetralin); Ontogeny (Spear, L.P. (203) 9) Methamphetamine Inhibitory postsynaptic potentials (monosynaptic) MDMA(3,4-methylenedioxymethamphetamine); p-Chloroampheta- Carbachol; Baclofen; Phorbol esters; (Disinhibition) (Lambert, N.A mine; Fenfluramine; Dopamine/serotonin neurotoxicity (Schmidt, (203) 129) C.J. (203) 41) Insulin secretion Middle cerebral artery Galanin; Pancreatic islets (Gregersen, S. (203) 111) Prostaglandin F,,,; Cerebral blood flow; Ca**-free medium; Ca** entry blockers (Salom, J.B. (203) 33) Intrapulmonary artery rings (sheep) Hypoxia; Flurbiprofen; Verapamil (Demiryurek, A.T. (203) 1) Miniature end-plate potential—fluoride Transmitter release; G-proteins; Protein kinase C (Light, P.E. (203) Ischaemia 311) Endothelin-1; Cerebral blood flow; Ischaemic pressor response MK 801 (Macrae, I. (203) 85) NMDA (N-methyl-D-aspartate); Phencyclidine (PCP); CPP (3-(2- carboxypiperazin-4-yl)-propyl-l-phosphonic acid); CGS 19755; 5- Ischaemic pressor response HT,, receptors; Tail flicks (spontaneous) (Millan, M.J. (203) 315) Endothelin-!; Cerebral blood flow; Ischaemia (Macrae, I. (203) 85) Morphine Ischemia Butorphanol; Withdrawal (precipitated and abrupt); Physical depen- Angiotensin I; Angiotensin Il; Angiotensin-converting enzyme dence (Horan, P. (203) 387) (cardiac); Heart (isolated); Coronary flow; Hypoxia (Tian, R. (203) 71) Morphine withdrawal Spinal morphine; Physical dependence; [Met°Jenkephalin levels Isethionate (Cridland, R.A. (203) 93) Smooth muscle (vascular); Cl~ ions; Ca** movement; Anion ex change inhibitors; Cl~ channels; Caffeine (Zhang, A. (203) 223) Muscarinic M, heteroreceptors (prejunctional) Muscarinic receptor agonists; Vas deferens (rabbit); Ca**; Piren- Isoflurane zepine; 4-Cl-McN-A-343 (Dorje, F. (203) 417) Anaesthetics (volatile); Halothane; Arachidonic acid cascade; G-pro- teins; Myocardial contractility; (Rat) (Vulliemoz, Y. (203) 345) Muscarinic receptor agonists Muscarinic M, heteroreceptors (prejunctional); Vas deferens (rabbit); Ketamine Ca**; Pirenzepine; 4-Cl-McN-A-343 (Dérje, F. (203) 417) Halothane; Pentobarbitone; Urethane; Ether; Alphaxalone; Diiso propylphenol; Lignocaine; Ca** currents (axonal); Olfactory cortex Muscarinic receptors (McGivern, J. (203) 59) Tetrahydroaminoacridine; Muscarinic receptor subtypes; Allosteric antagonists; Brain; (Rat) (Kiefer-Day, J.S. (203) 421) Kidney NPY receptors; NPY Y, receptor agonists; NPY Y, receptor ago- Muscarinic receptor subtypes nists; Spleen; Nasal mucosa; Vasoconstriction; Vas deferens (Modin, Tetrahydroaminoacridine; Muscarinic receptors; Allosteric antago- A. (203) 165) nists; Brain; (Rat) (Kiefer-Day, J.S. (203) 421) LiCl Myenteric plexus cAMP; Adenylate cyclase; Myenteric plexus; LiCl-treated animals LiCl; cAMP; Adenylate cyclase; LiCl-treated animals (chronically); (chronically); Phosphodiesterase inhibitors; (Isolated organ bath) Phosphodiesterase inhibitors; (Isolated organ bath) (Marmol, F. (203) (Marmol, F. (203) 181) 181) LiCl-treated animals (chronically) Myocardial contractility LiCl; cAMP; Adenylate cyclase; Myenteric plexus; Phosphodi- Anaesthetics (volatile); Halothane; Isoflurane; Arachidonic acid cas- esterase inhibitors; (Isolated organ bath) (Marmol, F. (203) 181) cade; G-proteins; (Rat) (Vulliemoz, Y. (203) 345)

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