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European Journal of Pharmacology 1991: Vol 201 Index PDF

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European Journal of Pharmacology, 201 (1991) 253-255 © 1991 Elsevier Science Publishers B.V. All rights reserved 0014-/2919 /9$039.5 0 Author index Abdi, S., see Loick, H.M. (201) 91 Engberg, G. and Wikstrom, H. Adams, R.N., see Cammack, J. (201) 111 a-Receptors: implication for the control of neuronal activity of Agen, C., see Blandizzi, C. (201) 35 nigral dopamine-containing neurons (201) 199 Allix, M., see Plotkine, M. (201) 115 Enna, S.J., see Noronha-Blob, L. (201) 135 Balazs, R., see Van der Valk, J.B.F. (201) 247 Fardin, V. and Garret, C. Bang, L., see Nielsen-Kudsk, J.E. (201) 97 Species differences between [*H]substance P binding in rat and Bengtsson, S., see Hall, H. (201) 1 guinea-pig shown by the use of peptide agonists and antagonists Blandizzi, C., De Bona, M., Natale, G., Agen, C. and Del Tacca, M. (201) 231 Effects of quinolone carboxylic acid derivatives on GABA, re- Fernandez-Alfonso, M.S., see Marin, J. (201) 75 ceptor-mediated stimulation of gastric acid secretion and intesti- Ferreira, S.H., Duarte, 1.D.G. and Lorenzetti, B.B. nal motility (201) 35 The molecular mechanism of action of peripheral morphine Boddeke, H.W.G.M. analgesia: stimulation of the cGMP system via nitric oxide release Different effects of muscarinic agonists in rat superior cervical (201) 121 ganglion and hippocampal slices (201) 191 Foulkes, R., Shaw, N., Bose, C. and Hughes, B. Bose, C., see Foulkes, R. (201) 143 Differential vasodilator profile of calcitonin gene-related peptide Boulu, R., see Plotkine, M. (201) 115 in porcine large and small diameter coronary artery rings (201) Boura, A.L.A., see Rechtman, M.P. (201) 69 143 Bult, H., see Corten, I. (201) 83 Buyssens, N., see Corten, I. (201) 83 Garret, C., see Fardin, V. (201) 231 Gessa, G.L., see Rossetti, Z.L. (201) 243 Cammack, J., Tessel, R., Michaelis, E. and Adams, R.N. Goto, M., see Nakazawa, T. (201) 185 Antioxidants prevent the interaction of 3,4-dihydroxyphenylacetic Grande, P., see Stawski, G. (201) 123 acid at the dopamine D, receptor (201) 111 Guillou, J., see Plotkine, M. (201) 115 Caporali, M.G., see Popoli, P. (201) 11 Chang, K.-J., see Xu, S. (201) 215 Hall, H., Hogberg, T., Halldin, C., Bengtsson, S. and Wedel, I. Chang, L.-R., see Tao, P.-L. (201) 209 Synthesis and binding properties of the fluorinated substituted Chariot, J., see Nagain, C. (201) 203 benzamide [7H]NCQ 115, a new selective dopamine D, receptor Chess-Williams, R., see Coker, S.J. (201) 103 ligand (201) 1 Cho, C.H., Liao, N.X., Liu, X.G., Hui, W.M., Luk, C.T. and Lam, Halldin, C., see Hall, H. (201) 1 S.K. Henry, J.L., see Hong, Y. (201) 171 Effects of adenosine on gastric and cardiovascular systems, and Herman, A.G., see Corten, I. (201) 83 ethanol ulceration in male and female rats (201) 157 Herndon, D.L., see Loick, H.M. (201) 91 Clark, D., see Overton, P. (201) 117 Hmaidan, Y., see Rossetti, Z.L. (201) 243 Code, R.A. and Tang, A.H. Hogberg, T., see Hall, H. (201) 1 Yawning produced by dopamine agonists in rhesus monkeys (201) Hong, Y. and Henry, J.L. 235 Phaclofen-reversible effects of GABA in the spinal cord of the Coker, S.J. and Chess-Williams, R. rat (201) 171 Amiodarone, adrenoceptor responsiveness and ischaemia- and Hughes, B., see Foulkes, R. (201) 143 reperfusion-induced arrhythmias (201) 103 Hui, W.M., see Cho, C.H. (201) 157 Collins, M.A., see Xu, S. (201) 215 Cools, A.R., see Koshikawa, N. (201) 47 Jean, A., see Kessler, J.-P. (201) 59 Corten, I., Peeters, F.A.M., Rampart, M., Bult, H., Buyssens, N. and Johnson, D.N., see Young, R. (201) 151 Herman, A.G. Ridogrel prevents the thromboxane-mediated pressor response Kameyama, T., see Toyoshi, T. (201) 41 and oedema induced by hydrogen peroxide in isolated rabbit Kaneko, T., see Nakazawa, T. (201) 185 lungs (201) 83 Katz, J.L., see Menkel, M. (201) 251 Kessler, J.-P. and Jean, A. D’ Aquila, P.S., see Rossetti, Z.L. (201) 243 Evidence that activation of N-methyl-D-aspartate (NMDA) and De Beltran, K.K., see Koshikawa, N. (201) 47 non-NMDA receptors within the nucleus tractus solitarii triggers De Bona, M., see Blandizzi, C. (201) 35 swallowing (201) 59 De Carolis, A.S., see Popoli, P. (201) 11 King, R.G., see Rechtman, M.P. (201) 69 De Jong, W., see Linthorst, A.C.E. (201) 125 Kobayashi, M., see Koshikawa, N. (201) 47 De Lang, H., see Linthorst, A.C.E. (201) 125 Koshikawa, N., De Beltran, K.K., Tomiyama, K., Kobayashi, M. and Del Tacca, M., see Blandizzi, C. (201) 35 Cools, A.R. Duarte, I.D.G., see Ferreira, S.H. (201) 121 Functional interaction between dopamine D, and D, receptors Dirmiiller, N., see Smith, S.E. (201) 179 in rat jaw movements (201) 47 254 Lam, S.K., see Cho, C.H. (201) 157 Hypothermia augments non-cholinergic neuronal bronchocon- Laubie, M., see Verbeuren, T.J. (201) 17 striction in pithed guinea-pigs (201) 69 Lee, M., see Strahlendorf, J.C. (201) 239 Resink, A., see Van der Valk, J.B.F. (201) 247 Liao, N.X., see Cho, C.H. (201) 157 Rossetti, Z.L., D’Aquila, P.S., Hmaidan, Y., Gessa, G.L. and Serra, Linthorst, A.C.E., De Lang, H., De Jong, W. and Versteeg, D.H.G. G. Effect of the dopamine D, receptor agonist quinpirole on the in Repeated treatment with imipramine potentiates cocaine-in- vivo release of dopamine in the caudate nucleus of hypertensive duced dopamine release and motor stimulation (201) 243 rats (201) 125 Rozé, C., see Nagain, C. (201) 203 Liu, X.G., see Cho, C.H. (201) 157 Loh, H.H., see Tao, P.-L. (201) 209 Sanchez-Ferrer, C.F., see Marin, J. (201) 75 Loick, H.M., Tokyay, R., Abdi, S., Traber, D.L., Nichols, R.J. and Serra, G., see Rossetti, Z.L. (201) 243 Herndon, D.L. Shaw, N., see Foulkes, R. (201) 143 Halothane markedly reduces mesenteric blood flow but does not Smith, S.E., Durmuller, N. and Meldrum, B.S. impair gut mucosal oxygenation in pigs (201) 91 The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 Lorenzetti, B.B., see Ferreira, S.H. (201) 121 and NBQX are anticonvulsant in two animal models of reflex Lowe, V.C., see Noronha-Blob, L. (201) 135 epilepsy (201) 179 Luk, C.T., see Cho, C.H. (201) 157 Sprouse, J.S. Inhibition of dorsal raphe cell firing by MDL 73005EF, a novel Marin, J., Fernandez-Alfonso, M.S. and Sanchez-Ferrer, C.F. 5-HT,, receptor ligand (201) 163 Sodium punip activity and contractile effect of ouabain in human Stawski, G., Olsen, U.B. and Grande, P. placental veins (201) 75 Cytotoxic effect of endothelin-1 during ‘simulated’ ischaemia in Marshall, I.G., see Wannan, G. (201) 29 cultured rat myocytes (201) 123 Meldrum, B.S., see Smith, S.E. (201) 179 Strahlendorf, H.K., see Strahlendorf, J.C. (201) 239 Menkel, M., Terry, P., Pontecorvo, M., Katz, J.L. and Witkin, J.M. Strahlendorf, J.C., Lee, M. and Strahlendorf, H.K. Selective o ligands block stimulant effects of cocaine (201) 251 Serotonin modulates muscimol- and baclofen-elicited inhibition Mennecier, P., see Verbeuren, T.J. (201) 17 of cerebellar Purkinje cells (201) 239 Michaelis, E., see Cammack, J. (201) 111 Sturm, B.L., see Noronha-Blob, L. (201) 135 Nagain, C., Chariot, J., Vaille, C. and Rozé, C. Tachibana, S., see Nakazawa, T. (201) 185 Effect of modafinil on pancreatic exocrine secretion in the rat. A Taki, T., see Nakazawa, T. (201) 185 comparison with methadone (201) 203 Tang, A.H., see Code, R.A. (201) 235 Nakazawa, T., Kaneko, T., Yoshino, H., Tachibana, S., Goto, M., Tao, P.-L., Tsai, C.-L., Chang, L.-R. and Loh, H.H. Taki, T. and Yamatsu, K. Chronic effect of [D-Pen?,D-Pen* enkephalin on rat brain opioid Physical dependence liability of dynorphin A analogs in rodents receptors (201) 209 (201) 185 Terry, P., see Menkel, M. (201) 251 Natale, G., see Blandizzi, C. (201) 35 Tessel, R., see Cammack, J. (201) 111 Nichols, R.J., see Loick, H.M. (201) 91 Toda, N., see Yamazaki, M. (201) 223 Nielsen-Kudsk, J.E. and Bang, L. Tokyay, R., see Loick, H.M. (201) 91 Effects of pinacidil and other cyanoguanidine derivatives on Tomiyama, K., see Koshikawa, N. (201) 47 guinea-pig isolated trachea, aorta and pulmonary artery (201) 97 Toyoshi, T., Ukai, M. and Kameyama, T. Noronha-Blob, L., Prosser, J.C., Sturm, B.L., Lowe, V.C. and Enna, [D-Ala*,NMePhe‘*,Gly-ol°Jenkephalin, but not [D-Pen?,L- S.J. Pen Jenkephalin, specifically inhibits behaviors induced by the (+)-Terodiline: an M,-selective muscarinic receptor antagonist. dopamine D, agonist RU 24213 (201) 41 In vivo effects at muscarinic receptors mediating urinary bladder Traber, D.L., see Loick, H.M. (201) 91 contraction, mydriasis and salivary secretion (201) 135 Trautmann, M., Peskar, B.M. and Peskar, B.A. Aspirin-like drugs, ethanol-induced rat gastric injury and mucosal Olsen, U.B., see Stawski, G. (201) 123 eicosanoid release (201) 53 Overton, P. and Clark, D. Tsai, C.-L., see Tao, P.-L. (201) 209 N-Methyl-D-aspartate increases the excitability of nigrostriatal dopamine terminals (201) 117 Ukai, M., see Toyoshi, T. (201) 41 Peeters, F.A.M., see Corten, I. (201) 83 Peskar, B.A., see Trautmann, M. (201) 53 Vaille, C., see Nagain, C. (201) 203 Peskar, B.M., see Trautmann, M. (201) 53 Van der Valk, J.B.F., Resink, A. and Balazs, R. Plotkine, M., Allix, M., Guillou, J. and Boulu, R. Membrane depolarization and the expression of glutamate recep- Oral administration of isosorbide dinitrate inhibits arterial tors in cerebellar granule cells (201) 247 thrombosis in rats (201) 115 Verbeuren, T.J., Mennecier, P. and Laubie, M. Pontecorvo, M., see Menkel, M. (201) 251 5-Hydroxytryptamine-induced vasodilatation in the isolated per- Popoli, P., Caporali, M.G. and De Carolis, A.S. fused rat kidney: are endothelial 5-HT,, receptors involved? Interactions between dopamine D, and D, receptors in the (201) 17 model of thyrotropin-releasing hormone (TRH)-induced be- Versteeg, D.H.G., see Linthorst, A.C.E. (201) 125 haviour in rabbits (201) 11 Prior, C., see Wannan, G. (201) 29 Wannan, G., Prior, C. and Marshall, I.G. Prosser, J.C., see Noronha-Blob, L. (201) 135 a-Adrenoceptor blocking properties of vesamicol (201) 29 Wedel, I., see Hall, H. (201) 1 Rampart, M., see Corten, I. (201) 83 Wikstrom, H., see Engberg, G. (201) 199 Rechtman, M.P., King, R.G. and Boura, A.L.A. Witkin, J.M., see Menkel, M. (201) 251 255 Xu, S., Collins, M.A. and Chang, K.-J. Comparison of responses to angiotensin II of dog mesenteric Phorbol esters induce oscillatory contractions of intestinal smooth arteries and veins (201) 223 muscles (201) 215 Yoshino, H., see Nakazawa, T. (201) 185 Young, R. and Johnson, D.N. Yamatsu, K., see Nakazawa, T. (201) 185 Anxiolytic-like activity of R(+)- and S(—)-zacopride in mice Yamazaki, M. and Toda, N. (201) 151 European Journal of Pharmacology, 201 (1991) 257-262 © 1991 Elsevier Science Publishers B.V. All rights reserved 0014-/2919 /9$039.5 0 Key word index Adenosine Arrhythmias Ethanol; Gastric mucosal blood flow; Gastric secretion; Gastric Amiodarone; Coronary artery occlusion; Reperfusion; Adrenoceptor damage; Cardiovascular system; (Rat) (Cho, C.H. (201) 157) responsiveness (Coker, S.J. (201) 103) Adrenoceptor responsiveness Arterial pressure Amiodarone; Coronary artery occlusion; Reperfusion; Arrhythmias GABA (y-aminobutyric acid); Bicuculline; Phaclofen; Heart rate; (Coker, S.J. (201) 103) Spinal cord; (Intrathecal) (Hong, Y. (201) 171) Adrenoceptors Arterial thrombosis Pancreatic exocrine secretion; Modafinil; Methadone; Opiate recep- Isosorbide dinitrate; Nitrovasodilators; Antithrombotics; (Rat) tors (Nagain, C. (201) 203) (Plotkine, M. (201) 115) a -Adrenoceptors Ascorbic acid Vesamicol; AH5183; Vas deferens (rat); Uptake, (Wannan, G. (201) DOPAC (3,4-dihydroxyphenylacetic acid); Dopamine D, receptors; 29) Auto-oxidation (Cammack, J. (201) 111) Auto-oxidation AHS5183 DOPAC (3,4-dihydroxyphenylacetic acid); Ascorbic acid; Dopamine Vesamicol; Vas deferens (rat); a-Adrenoceptors; Uptake, (Wannan, D, receptors (Cammack, J. (201) 111) G. (201) 29) Baclofen Amiodarone 5-HT (5-hydroxytryptamine, serotonin); Muscimol; Cerebellum; Coronary artery occlusion; Reperfusion; Arrhythmias; Adrenoceptor Purkinje cells (Strahlendorf, J.C. (201) 239) responsiveness (Coker, S.J. (201) 103) Behaviour Angiotensin II Dopamine D, receptors; Dopamine D, receptors; Thyrotropin-re- Prostaglandin I,; Mesenteric artery; Mesenteric vein; EDRF (endo- leasing hormone (TRH); (Rabbit) (Popoli, P. (201) 11) thelium-derived relaxing factor) (Yamazaki, M. (201) 223) Benzamides (fluorinated, substituted) Antidepressants Dopamine D, receptors; Receptor binding (in vitro) (Hall, H. (201) Microdialysis; Cocaine; Reward (Rossetti, Z.L. (201) 243) 1) Antiinflammatory drugs (non-steroidal) Bicuculline Gastric injury (rat); Leukotriene C,; 6-keto-Prostaglandin F,,; 15- GABA (y-aminobutyric acid); Phaclofen; Arterial pressure; Heart Hydroxy-5,8,11,13-eicosatetraenoic acid; Gastroprotection (Traut- rate; Spinal cord; (Intrathecal) (Hong, Y. (201) 171) mann, M. (201) 53) Bladder instability Antithrombotics Terodiline; Pirenzepine; Propantheline; Urinary incontinence; Mus- Isosorbide dinitrate; Nitrovasodilators; Arterial thrombosis; (Rat) carinic receptor subtypes; Cystometrogram; Mydriasis; Salivation (Plotkine, M. (201) 115) (Noronha-Blob, L. (201) 135) Anxiolytic activity Bradykinin 5-HT (5-hydroxytryptamine, serotonin); 5-HT,, receptors; Dorsal Protein kinase C; Ca” *-channel inhibitors; Nifedipine; Ca* *-mobiliz- raphe nucleus; Receptor reserve; 8-OH-DPAT (8-hydroxy-2-(di-n- ing ligands; Muscarinic receptor agonists; Histamine (Xu, S. (201) propylamino)tetralin); Buspirone; (Autoreceptor) (Sprouse, J.S. (201) 215) 163) Brain (guinea-pig) Anxiolytic-like activity Brain (rat); Ileum (guinea-pig); Substance P; Tachykinin receptors Light /dark test; Zacopride isomers (Young, R. (201) 151) (Fardin, V. (201) 231) Aorta Brain (rat) Pinacidil; Cyanoguanidines; K* channels; Trachea; Pulmonary artery Ileum (guinea-pig); Brain (guinea-pig); Substance P; Tachykinin re- (Nielsen-Kudsk, J.E. (201) 97) ceptors (Fardin, V. (201) 231) Apomorphine Bronchoconstriction o-Receptors; Substantia nigra; Dopamine neurons; (+ )-3-PPP ((+)- Non-cholinergic response; Substance P; Temperature; (Guinea-pig) 3-(3-hydroxyphenyl)-N-(1-propyl)piperidine) (Engberg, G. (201) 199) (Rechtman, M.P. (201) 69) 258 Buspirone DOPAC (3,4-dihydroxyphenylacetic acid) 5-HT (5-hydroxytryptamine, serotonin); 5-HT,, receptors; Dorsal Ascorbic acid; Dopamine D, receptors; Auto-oxidation (Cammack, raphe nucleus; Receptor reserve; Anxiolytic activity; 8-OH-DPAT J. (201) 111) (8-hydroxy-2-(di-n-propylamino)tetralin); (Autoreceptor) (Sprouse, J.S. (201) 163) Dopamine Glutamate; NMDA (N-methyl-D-aspartate); Terminal excitability; Ca?*-channel inhibitors Neostriatum; (Rat) (Overton, P. (201) 117) Protein kinase C: Nifedipine; Ca?*-mobilizing ligands; Muscarinic receptor agonists; Histamine; Bradykinin (Xu, S. (201) 215) Quinpirole; Caudate nucleus; Spontaneously hypertensive rat (SHR); Hypertension; Microdialysis (Linthorst, A.C.E. (201) 125) Ca?*-mobilizing ligands Protein kinase C; Ca**-channel inhibitors; Nifedipine; Muscarinic Dopamine neurons receptor agonists; Histamine; Bradykinin (Xu, S. (201) 215) o-Receptors; Substantia nigra; Apomorphine; (+ )-3-PPP ((+ )-3-(3- hydroxyphenyl)-N-(1-propyl)piperidine) (Engberg, G. (201) 199) 5-Carboxamidotryptamine Renal vasodilatation; Endothelium dilatation; 5-HT,, receptors; 8- Dopamine D, /D, receptor interaction OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin); Tertatolol Oral movements; Electromyographic activity; SK&F 38393; Quinpi- (Verbeuren, T.J. (201) 17) role; (Rat) (Koshikawa, N. (201) 47) Dopamine D, receptors Cardiovascular system Dopamine D, receptors; Thyrotropin-releasing hormone (TRH); Adenosine; Ethanol; Gastric mucosal blood flow; Gastric secretion; Gastric damage; (Rat) (Cho, C.H. (201) 157) Behaviour; (Rabbit) (Popoli, P. (201) 11) Dopamine D, receptors Caudate nucleus Benzamides (fluorinated, substituted); Receptor binding (in vitro) Dopamine; Quinpirole; Spontaneously hypertensive rat (SHR); Hy- (Hall, H. (201) 1) pertension; Microdialysis (Linthorst, A.C.E. (201) 125) Dopamine D, receptors; Thyrotropin-releasing hormone (TRH); Be- Cerebellum haviour; (Rabbit) (Popoli, P. (201) 11) 5-HT (5-hydroxytryptamine, serotonin); Muscimol; Baclofen; Pur- kinje cells (Strahlendorf, J.C. (201) 239) DOPAC (3,4-dihydroxyphenylacetic acid); Ascorbic acid; Auto- oxidation (Cammack, J. (201) 111) Granule cells; Glutamate; Excitatory amino acid receptors; Trophic factors; Voltage clamp (Van der Valk, J.B.F. (201) 247) Dopaminergic compounds Yawning; (Rhesus monkey) (Code, R.A. (201) 235) CGRP-(8-37) CGRP (calcitonin gene-related peptide); Coronary artery (porcine); Dorsal raphe nucleus Vasodilators (Foulkes, R. (201) 143) 5-HT (5-hydroxytryptamine, serotonin); 5-HT,, receptors; Receptor reserve; Anxiolytic activity; 8-OH-DPAT (8-hydroxy-2-(di-n-pro- CGRP (calcitonin gene-related peptide) pylamino)tetralin); Buspirone; (Autoreceptor) (Sprouse, J.S. (201) CGRP-(8-37); Coronary artery (porcine); Vasodilators (Foulkes, R. 163) (201) 143) DPDPE ([D-Pen?,D-Pen*]enkephalin) Cocaine Tolerance; Opioid receptors; (Rat) (Tao, P.-L. (201) 209) Antidepressants; Microdialysis; Reward (Rossetti, Z.L. (201) 243) DPLPE ([D-Pen’,L-Pen*]enkephalin) Coronary artery occlusion DAGO ({D-Ala?,NMePhe‘*,Gly-ol°]enkephalin); RU 24213; B- Amiodarone; Reperfusion; Arrhythmias; Adrenoceptor responsive- Funaltrexamine; Locomotor activity; (Mouse) (Toyoshi, T. (201) 41) ness (Coker, S.J. (201) 103) Dynorphin A analogs Coronary artery (porcine) E-2078; Physical dependence (Nakazawa, T. (201) 185) CGRP (calcitonin gene-related peptide); CGRP-(8-37); Vasodilators (Foulkes, R. (201) 143) E-2078 Dynorphin A analogs; Physical dependence (Nakazawa, T. (201) 185) Cyanoguanidines Pinacidil; K* channels; Trachea; Pulmonary artery; Aorta (Nielsen- EDRF (endothelium-derived relaxing factor) Kudsk, J.E. (201) 97) Angiotensin II; Prostaglandin I,; Mesenteric artery; Mesenteric vein (Yamazaki, M. (201) 223) Cystometrogram Terodiline; Pirenzepine; Propantheline; Bladder instability; Urinary Electromyographic activity incontinence; Muscarinic receptor subtypes; Mydriasis; Salivation Oral movements; SK&F 38393; Quinpirole; Dopamine D, /D, re- (Noronha-Blob, L. (201) 135) ceptor interaction; (Rat) (Koshikawa, N. (201) 47) DAGO ([D-Ala?,NMePhe‘*,Gly-ol>]enkephalin) Endothelial distress DPLPE ([D-Pen’,L-Pen> Jenkephalin); RU 24213; B-Funaltrexamine; H,O,; Ridogrel; Thromboxane; 5-HT uptake; Lung (rabbit) (Corten, Locomotor activity; (Mouse) (Toyoshi, T. (201) 41) I. (201) 83) Endothelium dilatation Gastroprotection Renal vasodilatation; 5-HT,, receptors; 8-OH-DPAT (8-hydroxy-2- Gastric injury (rat); Leukotriene C,; 6-keto-Prostaglandin F,,; 15- (di-n-propylamino)tetralin); 5-Carboxamidotryptamine; Tertatolol Hydroxy-5,8,11,13-eicosatetraenoic acid; Antiinflammatory drugs (Verbeuren, T.J. (201) 17) (non-steroidal) (Trautmann, M. (201) 53) Epilepsy Glutamate Quisqualate; NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)- Dopamine; NMDA (N-methyl-D-aspartate); Terminal excitability; quinoxaline); Non-NMDA receptor antagonists; GYKI 52466; Exci- Neostriatum; (Rat) (Overton, P. (201) 117) tatory amino acids (Smith, S.E. (201) 179) Cerebellum; Granule cells; Excitatory amino acid receptors; Trophic Ethanol factors; Voltage clamp (Van der Valk, J.B.F. (201) 247) Adenosine; Gastric mucosal blood flow; Gastric secretion; Gastric damage; Cardiovascular system; (Rat) (Cho, C.H. (201) 157) Granule cells Cerebellum; Glutamate; Excitatory amino acid receptors; Trophic Excitatory amino acid receptors factors; Voltage clamp (Van der Valk, J.B.F. (201) 247) Cerebellum; Granule cells; Glutamate; Trophic factors; Voltage clamp (Van der Valk, J.B.F. (201) 247) GYKI 52466 Quisqualate; NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)- Excitatory amino acids quinoxaline); Non-NMDA receptor antagonists; Excitatory amino Quisqualate; NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)- acids; Epilepsy (Smith, S.E. (201) 179) quinoxaline); Non-NMDA receptor antagonists; GYKI 52466; Epilepsy (Smith, S.E. (201) 179) Halothane Mesenteric blood flow; Mucosal perfusion; (Pig) (Loick, H.M. (201) B-Funaltrexamine 91) DAGO ((D-Ala?,NMePhe?4,Gly-ol°Jenkephalin); DPLPE ((D- Pen’,L-Pen° Jenkephalin); RU 24213; Locomotor activity; (Mouse) Heart rate (Toyoshi, T. (201) 41) GABA (y-aminobutyric acid); Bicuculline; Phaclofen; Arterial pres- sure; Spinal cord; (Intrathecal) (Hong, Y. (201) 171) GABA (y-aminobutyric acid) Bicuculline; Phaclofen; Arterial pressure; Heart rate; Spinal cord; Hippocampal slice (rat) (Intrathecal) (Hong, Y. (201) 171) Superior cervical ganglion (rat); Muscarinic M, receptors (Boddeke, H.W.G.M. (201) 191) GABA, receptor agonists Quinolone carboxylic acid; GABA, receptors; GABA, receptor Histamine antagonists; Gastric acid secretion; Intestinal motility (Blandizzi, C. Protein kinase C; Ca?*-channel inhibitors; Nifedipine; Ca? *-mobiliz- (201) 35) ing ligands; Muscarinic receptor agonists; Bradykinin (Xu, S. (201) 215) GABA, receptor antagonists Quinolone carboxylic acid; GABA, receptors; GABA, receptor H,0, agonists; Gastric acid secretion; Intestinal motility (Blandizzi, C. Ridogrel; Thromboxane; 5-HT uptake; Endothelial distress; Lung (201) 35) (rabbit) (Corten, I. (201) 83) GABA , receptors 5-HT (5-hydroxytryptamine, serotonin) Quinolone carboxylic acid; GABA, receptor agonists; GABA, re- 5-HT,, receptors; Dorsal raphe nucleus; Receptor reserve; Anxi- ceptor antagonists; Gastric acid secretion; Intestinal motility (Blan- olytic activity; 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin); dizzi, C. (201) 35) Buspirone; (Autoreceptor) (Sprouse, J.S. (201) 163) Gastric acid secretion Muscimol; Baclofen; Cerebellum; Purkinje cells (Strahlendorf, J.C. Quinolone carboxylic acid; GABA, receptors; GABA, receptor (201) 239) agonists; GABA , receptor antagonists; Intestinal motility (Blandizzi, C. (201) 35) 5-HT,, receptors Renal vasodilatation; Endothelium dilatation; 8-OH-DPAT (8-hy- Gastric damage droxy-2-(di-n-propylamino)tetralin); 5-Carboxamidotryptamine; Ter- Adenosine; Ethanol; Gastric mucosal blood flow; Gastric secretion; tatolol (Verbeuren, T.J. (201) 17) Cardiovascular system; (Rat) (Cho, C.H. (201) 157) 5-HT (5-hydroxytryptamine, serotonin); Dorsal raphe nucleus; Re- Gastric injury (rat) ceptor reserve; Anxiolytic activity; 8-OH-DPAT (8-hydroxy-2-(di-n- Leukotriene C,; 6-keto-Prostaglandin F,,; 15-Hydroxy-5,8,11,13- propylamino)tetralin); Buspirone; (Autoreceptor) (Sprouse, J.S. (201) eicosatetraenoic acid; Antiinflammatory drugs (non-steroidal); Gas- 163) troprotection (Trautmann, M. (201) 53) 5-HT uptake Gastric mucosal blood flow H,0,; Ridogrel; Thromboxane; Endothelial distress; Lung (rabbit) Adenosine; Ethanol; Gastric secretion; Gastric damage; Cardiovas- (Corten, I. (201) 83) cular system; (Rat) (Cho, C.H. (201) 157) 15-Hydroxy-5,8,11,13-eicosatetraenoic acid Gastric injury (rat); Leukotriene C,; 6-keto-Prostaglandin F,,,; Anti- Gastric secretion Adenosine; Ethanol; Gastric mucosal blood flow; Gastric damage; inflammatory drugs (non-steroidal); Gastroprotection (Trautmann, Cardiovascular system; (Rat) (Cho, C.H. (201) 157) M. (201) 53) 260 Hypertension Mucosal perfusion Dopamine; Quinpirole; Caudate nucleus; Spontaneously hyperten- Halothane; Mesenteric blood flow; (Pig) (Loick, H.M. (201) 91) sive rat (SHR); Microdialysis (Linthorst, A.C.E. (201) 125) Muscarinic receptor agonists Ileum (guinea-pig) Protein kinase C; Ca?*-channel inhibitors; Nifedipine; Ca? *-mobiliz- Brain (rat); Brain (guinea-pig); Substance P; Tachykinin receptors ing ligands; Histamine; Bradykinin (Xu, S. (201) 215) (Fardin, V. (201) 231) Muscarinic M, receptors Intestinal motility Superior cervical ganglion (rat); Hippocampal slice (rat) (Boddeke, Quinolone carboxylic acid; GABA, receptors; GABA, receptor H.W.G.M. (201) 191) agonists; GABA, receptor antagonists; Gastric acid secretion (Blandizzi, C. (201) 35) Muscarinic receptor subtypes Terodiline; Pirenzepine; Propantheline; Bladder instability; Urinary Isosorbide dinitrate incontinence; Cystometrogram; Mydriasis; Salivation (Noronha-Blob, Nitrovasodilators; Arterial thrombosis; Antithrombotics; (Rat) L. (201) 135) (Plotkine, M. (201) 115) Muscimol K* channels 5-HT (5-hydroxytryptamine, serotonin); Baclofen; Cerebellum; Pur- Pinacidil; Cyanoguanidines; Trachea; Pulmonary artery; Aorta (Niel- kinje cells (Strahlendorf, J.C. (201) 239) sen-Kudsk, J.E. (201) 97) Mydriasis Leukotriene C, Terodiline; Pirenzepine; Propantheline; Bladder instability; Urinary Gastric injury (rat); 6-keto-Prostaglandin F,,,; 15-Hydroxy-5,8,11,13- incontinence; Muscarinic receptor subtypes; Cystometrogram; Saliva- eicosatetraenoic acid; Antiinflammatory drugs (non-steroidal); Gas- tion (Noronha-Blob, L. (201) 135) troprotection (Trautmann, M. (201) 53) NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo (F)-quinoxaline) Light /dark test Quisqualate; Non-NMDA receptor antagonists; GYKI 52466; Excita- Zacopride isomers; Anxiolytic-like activity (Young, R. (201) 151) tory amino acids; Epilepsy (Smith, S.E. (201) 179) Locomotor activity Neostriatum DAGO ({(D-Ala?,NMePhe?,Gly-ol°]Jenkephalin); DPLPE ({D- Dopamine; Glutamate; NMDA (N-methyl-D-aspartate); Terminal Pen’,L-Pen* Jenkephalin); RU 24213; B-Funaltrexamine; (Mouse) excitability; (Rat) (Overton, P. (201) 117) (Toyoshi, T. (201) 41) Nifedipine Lung (rabbit) Protein kinase C; Ca**-channel inhibitors; Ca?*-mobilizing ligands; H,O,; Ridogrel; Thromboxane; 5-HT uptake; Endothelial distress Muscarinic receptor agonists; Histamine; Bradykinin (Xu, S. (201) (Corten, I. (201) 83) 215) Mesenteric artery Nitrovasodilators Angiotensin II; Prostaglandin I,; Mesenteric vein; EDRF (endo- Isosorbide dinitrate; Arterial thrombosis; Antithrombotics; (Rat) thelium-derived relaxing factor) (Yamazaki, M. (201) 223) (Plotkine, M. (201) 115) Mesenteric blood flow NMDA (N-methyl-D-aspartate) Halothane; Mucosal perfusion; (Pig) (Loick, H.M. (201) 91) Dopamine; Glutamate; Terminal excitability; Neostriatum; (Rat) (Overton, P. (201) 117) Mesenteric vein Angiotensin II; Prostaglandin I,; Mesenteric artery; EDRF (endo- NMDA receptors thelium-derived relaxing factor) (Yamazaki, M. (201) 223) Swallowing; Non-NMDA receptors; Motor pattern; Nucleus tractus solitarii; (Decerebrate rat) (Kessler, J.-P. (201) 59) Methadone Pancreatic exocrine secretion; Adrenoceptors; Modafinil; Opiate re- Non-cholinergic response ceptors (Nagain, C. (201) 203) Bronchoconstriction; Substance P; Temperature; (Guinea-pig) (Rechtman, M.P. (201) 69) Microdialysis Dopamine; Quinpirole; Caudate nucleus; Spontaneously hyperten- Non-NMDA receptor antagonists sive rat (SHR); Hypertension (Linthorst, A.C.E. (201) 125) Quisqualate; NBOX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)- quinoxaline); GYKI 52466; Excitatory amino acids; Epilepsy (Smith, Antidepressants; Cocaine; Reward (Rossetti, Z.L. (201) 243) S.E. (201) 179) Modafinil Non-NMDA receptors Pancreatic exocrine secretion; Adrenoceptors; Methadone; Opiate Swallowing; NMDA receptors; Motor pattern; Nucleus tractus soli- receptors (Nagain, C. (201) 203) tarii; (Decerebrate iat) (Kessler, J.-P. (201) 59) Motor pattern Nucleus tractus solitarii Swallowing; NMDA receptors; Non-NMDA receptors; Nucleus trac- Swallowing; NMDA receptors; Non-NMDA receptors; Motor pat- tus solitarii; (Decerebrate rat) (Kessler, J.-P. (201) 59) tern; (Decerebrate rat) (Kessler, J.-P. (201) 59) 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin) Pulmonary artery Renal vasodilatation; Endothelium dilatation; 5-HT,, receptors; 5- Pinacidil; Cyanoguanidines; K* channels; Trachea; Aorta (Nielsen- Carboxamidotryptamine; Tertatolol (Verbeuren, T.J. (201) 17) Kudsk, J.E. (201) 97) 5-HT (5-hydroxytryptamine, serotonin); 5-HT,, receptors; Dorsal Purkinje cells raphe nucleus; Receptor reserve; Anxiolytic activity; Buspirone; (Au- 5-HT (5-hydroxytryptamine, serotonin); Muscimol; Baclofen; Cere- toreceptor) (Sprouse, J.S. (201) 163) bellum (Strahlendorf, J.C. (201) 239) Opiate receptors Quinolone carboxylic acid Pancreatic exocrine secretion; Adrenoceptors; Modafinil; Methadone GABA, receptors; GABA, receptor agonists; GABA, receptor (Nagain, C. (201) 203) antagonists; Gastric acid secretion; Intestinal motility (Blandizzi, C. (201) 35) Opioid receptors Tolerance; DPDPE ({D-Pen’,D-Pen? Jenkephalin); (Rat) (Tao, P.-L. Quinpirole (201) 209) Oral movements; Electromyographic activity; SK&F 38393; Dopamine D, /D, receptor interaction; (Rat) (Koshikawa, N. (201) Oral movements 47) Electromyographic activity; SK&F 38393; Quinpirole; Dopamine D, /D, receptor interaction; (Rat) (Koshikawa, N. (201) 47) Dopamine; Caudate nucleus; Spontaneously hypertensive rat (SHR); Hypertension; Microdialysis (Linthorst, A.C.E. (201) 125) Ouabain Placental vein (human); [*H]Ouabain binding; °°Rb* uptake (Marin, Quisqualate J. (201) 75) NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)-quinoxaline); Non-NMDA receptor antagonists; GYKI 52466; Excitatory amino [>H]Ouabain binding Placental vein (human); °°Rb* uptake; Ouabain (Marin, J. (201) 75) acids; Epilepsy (Smith, S.E. (201) 179) 8s6Rb* uptake Pancreatic exocrine secretion Adrenoceptors; Modafinil; Methadone; Opiate receptors (Nagain, C. Placental vein (human); [*H]Ouabain binding; Ouabain (Marin, J. (201) 203) (201) 75) Phaclofen Receptor binding (in vitro) GABA (y-aminobutyric acid); Bicuculline; Arterial pressure; Heart Benzamides (fluorinated, substituted); Dopamine D, receptors (Hall, rate; Spinal cord; (Intrathecal) (Hong, Y. (201) 171) H. (201) 1) Physical dependence Receptor reserve Dynorphin A analogs; E-2078 (Nakazawa, T. (201) 185) 5-HT (5-hydroxytryptamine, serotonin); 5-HT,, receptors; Dorsal raphe nucleus; Anxiolytic activity; 8-OH-DPAT (8-hydroxy-2-(di-n- Pinacidil propylamino)tetralin); Buspirone; (Autoreceptor) (Sprouse, J.S. (201) Cyanoguanidines; K* channels; Trachea; Pulmonary artery; Aorta 163) (Nielsen-Kudsk, J.E. (201) 97) o -Receptors Pirenzepine Substantia nigra; Dopamine neurons; Apomorphine; (+) -3-PPP Terodiline; Propantheline; Bladder instability; Urinary incontinence; ((+ )-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine) (Engberg, G. (201) Muscarinic receptor subtypes; Cystometrogram; Mydriasis; Salivation 199) (Noronha-Blob, L. (201) 135) Renal vasodilatation Placental vein (human) Endothelium dilatation; 5-HT,, receptors; 8-OH-DPAT (8-hydroxy- [?H]Ouabain binding; °°Rb* uptake; Ouabain (Marin, J. (201) 75) 2-(di-n-propylamino)tetralin); 5-Carboxamidotryptamine; Tertatolol (Verbeuren, T.J. (201) 17) Propantheline Terodiline; Pirenzepine; Bladder instability; Urinary incontinence; Reperfusion Muscarinic receptor subtypes; Cystometrogram; Mydriasis; Salivation Amiodarone; Coronary artery occlusion; Arrhythmias; Adrenoceptor (Noronha-Blob, L. (201) 135) responsiveness (Coker, S.J. (201) 103) 6-keto-Prostaglandin F,,, Reward Gastric injury (rat); Leukotriene C,; 15-Hydroxy-5,8,11,13-eico- Antidepressants; Microdialysis; Cocaine (Rossetti, Z.L. (201) 243) satetraenoic acid; Antiinflammatory drugs (non-steroidal); Gastro- protection (Trautmann, M. (201) 53) Ridogrel Prostaglandin I, H,O,; Thromboxane; 5-HT uptake; Endothelial distress; Lung (rab- bit) (Corten, I. (201) 83) Angiotensin II; Mesenteric artery; Mesenteric vein; EDRF (endo- thelium-derived relaxing factor) (Yamazaki, M. (201) 223) RU 24213 DAGO ({D-Ala*,NMePhe‘,Gly-ol° Jenkephalin); DPLPE ((D- Protein kinase C Ca**-channel inhibitors; Nifedipine; Ca**-mobilizing ligands; Mus- Pen?,L-Pen? Jenkephalin); B-Funaltrexamine; Locomotor activity; carinic receptor agonists; Histamine; Bradykinin (Xu, S. (201) 215) (Mouse) (Toyoshi, T. (201) 41) 262 Salivation OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin); 5-Carboxami- Terodiline; Pirenzepine; Propantheline; Bladder instability; Urinary dotryptamine (Verbeuren, T.J. (201) 17) incontinence; Muscarinic receptor subtypes; Cystometrogram; Mydri- asis (Noronha-Blob, L. (201) 135) Thromboxane H,0O,; Ridogrel; '5-HT uptake; Endothelial distress; Lung (rabbit) SK&F 38393 (Corten, I. (201) 83) Oral movements; Electromyographic activity; Quinpirole; Dopamine D, /D, receptor interaction; (Rat) (Koshikawa, N. (201) 47) Thyrotropin-releasing hormone (TRH) Dopamine D, receptors; Dopamine D, receptors; Behaviour; (Rab- Spinal cord bit) (Popoli, P. (201) 11) GABA (y-aminobutyric acid); Bicuculline; Phaclofen; Arterial pres- sure; Heart rate; (Intrathecal) (Hong, Y. (201) 171) Tolerance DPDPE ([D-Pen?,D-Pen° Jenkephalin); Opioid receptors; (Rat) (Tao, Spontaneously hypertensive rat (SHR) P.-L. (201) 209) Dopamine; Quinpirole; Caudate nucleus; Hypertension; Microdialy- sis (Linthorst, A.C.E. (201) 125) Trachea Pinacidil; Cyanoguanidines; K* channels; Pulmonary artery; Aorta Substance P (Nielsen-Kudsk, J.E. (201) 97) Non-cholinergic response; Bronchoconstriction; Temperature; (Guinea-pig) (Rechtman, M.P. (201) 69) Trophic factors Cerebellum; Granule cells; Glutamate; Excitatory amino acid recep- Brain (rat); Ileum (guinea-pig); Brain (guinea-pig); Tachykinin recep- tors; Voltage clamp (Van der Valk, J.B.F. (201) 247) tors (Fardin, V. (201) 231) Uptake, Substantia nigra Vesamicol; AH5183; Vas deferens (rat); a-Adrenoceptors (Wannan, o-Receptors; Dopamine neurons; Apomorphine; (+ )-3-PPP ((+ )-3- G. (201) 29) (3-hydroxyphenyl)-N-(1-propyl)piperidine) (Engberg, G. (201) 199) Urinary incontinence Superior cervical ganglion (rat) Terodiline; Pirenzepine; Propantheline; Bladder instability; Mus- Hippocampal slice (rat); Muscarinic M, receptors (Boddeke, carinic receptor subtypes; Cystometrogram; Mydriasis; Salivation H.W.G.M. (201) 191) (Noronha-Blob, L. (201) 135) Swallowing Vas deferens (rat) NMDA receptors; Non-NMDA receptors; Motor pattern; Nucleus Vesamicol; AH5183; a-Adrenoceptors; Uptake, (Wannan, G. (201) tractus solitarii; (Decerebrate rat) (Kessler, J.-P. (201) 59) 29) Tachykinin receptors Vasodilators Brain (rat); Ileum (guinea-pig); Brain (guinea-pig); Substance P CGRP (calcitonin gene-related peptide); CGRP-(8-37); Coronary (Fardin, V. (201) 231) artery (porcine) (Foulkes, R. (201) 143) Temperature Non-cholinergic response; Bronchoconstriction; Substance P; Vesamicol AHS5183; Vas deferens (rat); a-Adrenoceptors; Uptake, (Wannan, G. (Guinea-pig) (Rechtman, M.P. (201) 69) (201) 29) Terminal excitability Dopamine; Glutamate; NMDA (N-methyl-D-aspartate); Neostria- Voltage clamp tum; (Rat) (Overton, P. (201) 117) Cerebellum; Granule cells; Glutamate; Excitatory amino acid recep- tors; Trophic factors (Van der Valk, J.B.F. (201) 247) Terodiline Pirenzepine; Propantheline; Bladder instability; Urinary inconti- Yawning nence; Muscarinic receptor subtypes; Cystometrogram; Mydriasis; Dopaminergic compounds; (Rhesus monkey) (Code, R.A. (201) 235) Salivation (Noronha-Blob, L. (201) 135) Zacopride isomers Tertatolol Light /dark test; Anxiolytic-like activity (Young, R. (201) 151) Renal vasodilatation; Endothelium dilatation; 5-HT,, receptors; 8-

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