European Journal of Pharmacology 1991: Vol 193 Index

13 Pages·1991·2.7 MB·English

European Journal of Pharmacology, 193 (1991) 385-388
© 1991 Elsevier Science Publishers B.V. 0014-/2919 /9$039.5 0
Author index
Abe, Y., see Masumura, H. (193) 321 Chandan, R., O'Grady, S.M. and Brown, D.R.
Acquas, E., Carboni, E. and Di Chiara, G. Modulation of Na*, Cl” and HCO; transport by carbachol in
Profound depression of mesolimbic dopamine release after pig distal jejunum (193) 257
morphine withdrawal in dependent rats (193) 133 Chang, Y.-F., Gao, X.-M. and Chen, J.-S.
Adachi, H., Shoji, T. and Goto, K. Correlation between enhancement of [{*H]flunitrazepam binding
Comparison of the effects of endothelin and Bay k 8644 on and suppression of pentylenetetrazol-induced seizures by L-lysine
cardiohemodynamics in anesthetized pigs (193) 57 (193) 239
Adams, J.U. and Holtzman, S.G. Charney, D., see Innis, R. (193) 249
Naltrexone-sensitizing effects of centrally administered morphine Chen, J.-S., see Chang, Y.-F. (193) 239
and opioid peptides (193) 67 Chhajlani, V., see Wikberg, J.E.S. (193) 335
Akahane, K., see Furukawa, Y. (193) 217 Chi, E.M., see Kehne, J.H. (193) 283
Al-Tikriti, M., see Innis, R. (193) 249 Chi, Z.Q., see Wang, H. (193) 341
Albino-Teixeira, A., see Matias, A. (193) 101 Chiba, S., see Furukawa, Y. (193) 217
Ashida, S., see Masumura, H. (193) 321 Chung, K.F., see Tokuyama, K. (193) 35
Azevedo, I., see Matias, A. (193) 101 Clubb, Jr., F.J., see Rosolowsky, M. (193) 293
Colpaert, F.C., see Millan, M.J. (193) 145
Connick, J.H., see Fox, P.K. (193) 139
Baldwin, R., see Innis, R. (193) 249 Corda, M.G., see Giorgi, O. (193) 363
Barnes, P.J., see Tokuyama, K. (193) 35 Crespi, F., see Garratt, J.C. (193) 87
Baron, B.M., see Kehne, J.H. (193) 283
Baskys, A. and Malenka, R.C.
Datta, M.C., Dowla, H.A., Srivastava, K.K., Boswell, V.D. and
Trans-ACPD depresses synaptic transmission in the hippocampus
(193) 131 Washington, I.
Aspirin blocks 5-azacytidine- and hydroxyurea-induced changes in
Bast, A., see Doelman, C.J.A. (193) 117
Benito-Orfila, M.A., Domin, J., Nandha, K.A. and Bloom, S.R. hemoglobin proportions in adult rats (193) 173
Di Chiara, G., see Acquas, E. (193) 133
The motor effect of neuromedin U on rat stomach in vitro (193)
Doelman, C.J.A., Sprong, R.C., Nagtegaal, J.E. Rodrigues de
329
Miranda, J.F. and Bast, A.
Berkenboom, G., Fang, Z.-Y., Unger, P., Goldman, M. and Fontaine,
J. Prejunctional muscarinic receptors on cholinergic nerves in guinea
pig airways are of the M, subtype (193) 117
Endothelium-dependent effects of pentoxifylline in rat aorta (193)
Domin, J., see Benito-Orfila, M.A. (193) 329
81
Dourish, C.T., see O'Neill, M.F. (193) 203
Berkenkopf, J.W. and Weichman, B.M.
Dowla, H.A., see Datta, M.C. (193) 173
Comparison of several new 5-lipoxygenase inhibitors in a rat
Durcan, M.J., see Wozniak, K.M. (193) 253
arthus pleurisy model (193) 29
Biggs, D.F., see Yang, Z.-J. (193) 301
Bjérkman, R., see Gong, Q.-L. (193) 47 Elliott, P.J., see Higgins, G.A. (193) 351
Blanchard, J.-C., see Stutzmann, J.-M. (193) 223
Bloom, S.R., see Benito-Orfila, M.A. (193) 329
Fang, Z.-Y., see Berkenboom, G. (193) 81
Béhme, G.A., see Stutzmann, J.-M. (193) 223 Fontaine, J., see Berkenboom, G. (193) 81
Boswell, V.D., see Datta, M.C. (193) 173
Fox, P.K., Connick, J.H., Hanlon, G.M., France, L. and Nicholson,
Brown, D.R., see Chandan, R. (193) 257 C.D.
Brown, D.R., see Chandan, R. (193) 265
The lack of utility of the rat vas deferens as a functional bioassay
Buja, L.M., see Rosolowsky, M. (193) 293
for o ligands (193) 139
Burks, T.F., see Lemcke, P.K. (193) 109
France, L., see Fox, P.K. (193) 139
Bush, L.G., see Johnson, M. (193) 367
Fuhlendorff, J., see Potter, E.K. (193) 15
Furukawa, Y., Akahane, K., Ogiwara, Y. and Chiba, S.
K* channel blocking and anti-muscarinic effects of a novel
Campbell, W.B., see Rosolowsky, M. (193) 293
piperazine derivative, INO 2628, on the isolated dog atrium (193)
Candido, J., see Yoburn, B.C. (193) 105
217
Carboni, E., see Acquas, E. (193) 133
Cervo, L. and Samanin, R.
Clonidine causes antidepressant-like effects in rats by activating Gandolfo, G., see Stutzmann, J.-M. (193) 223
a,-adrenoceptors outside the locus coeruleus (193) 309 Gao, X.-M., see Chang, Y.-F. (193) 239
Chandan, R., Hildebrand, K.R., Seybold, V.S., Soldani, G. and Brown, Garratt, J.C., Crespi, F., Mason, R. and Marsden, C.A.
D.R. Effects of idazoxan on dorsal raphe 5-hydroxytryptamine neuronal
Cholinergic neurons and muscarinic receptors regulate anion function (193) 87
secretion in pig distal jejunum (193) 265 Gibb, J.W., see Johnson, M. (193) 367
386
Gilad, G.M. and Gilad, V.H. Effects of novel aldose reductase inhibitors, M16209 and M16287,
Polyamine uptake, binding and release in rat brain (193) 41 on streptozotocin-induced diabetic neuropathy in rats (193) 185
Gilad, V.H., see Gilad, G.M. (193) 41 Katoh, A., Nabeshima, T. and Kameyama, T.
Giorgi, O., Orlandi, M., Lecca, D. and Corda, M.G. Interaction between enkephalinergic and dopaminergic systems in
MK-801 prevents chemical kindling induced by pentylenetetrazol stressful situations (193) 95
in rats (193) 363 Kehne, J.H., McCloskey, T.C., Baron, B.M., Chi, E.M., Harrison,
Goldman, M., see Berkenboom, G. (193) 81 B.L., Whitten, J.P. and Palfreyman, M.G.
Gomes, B.C., see Sommerhoff, C.P. (193) 153 NMDA receptor complex antagonists have potential anxiolytic
Gong, Q.-L., Hedner, T., Hedner, J., Bjrkman, R. and Nordberg, G. effects as measured with separation-induced ultrasonic vocaliza-
Antinociceptive and ventilatory effects of the morphine metabo- tions (193) 283
lites: morphine-6-glucuronide and morphine-3-glucuronide (193) Kodama, I., see Shibata, S. (193) 1
47 Kolbasa, K.P., McCall, R.B. and Ludens, J.H.
Goto, K., see Adachi, H. (193) 57 Effect of chronic treatment on the cardiovascular and behavioral
Goto, K., see Shoji, T. (193) 371 responses of 8-OH-DPAT in conscious normotensive rats (193)
Gottesmann, C., see Stutzmann, J.-M. (193) 223 275
Kown, S.-C., see Shibata, S. (193) 1
Hall, J.M. and Morton, I.K.M. Krell, R.D., see Sommerhoff, C.P. (193) 153
Bradykinin B, receptor evoked K* permeability increase mediates Kunitada, S., see Masumura, H. (193) 321
Kurahashi, K., see Shibata, S. (193) 1
relaxation in the rat duodenum (193) 231
Hanlon, G.M., see Fox, P.K. (193) 139
Hanson, G.R., see Johnson, M. (193) 367 Laduron, P.M., see Stutzmann, J.-M. (193) 223
Harrison, B.L., see Kehne, J.H. (193) 283 Lafforgue, J., see Stutzmann, J.-M. (193) 223
Harro, J. and Vasar, E. Lazdunski, M., see Stutzmann, J.-M. (193) 223
Evidence that CCK, receptors mediate the regulation of explora- Lecca, D., see Giorgi, O. (193) 363
tory behaviour in the rat (193) 379 Lei, S.Z., Lipkowski, A.W. and Wilcox, G.L.
Hashimoto, K., see Satoh, H. (193) 9 Opioid and neurokinin activities of substance P fragments and
Hedner, J., see Gong, Q.-L. (193) 47 their analogs (193) 209
Hedner, T., see Gong, Q.-L. (193) 47 Lemcke, P.K., Shook, J.E. and Burks, T.F.
Spinally mediated opioid antidiarrheal effects (193) 109
Heninger, G., see Innis, R. (193) 249
Higgins, G.A. and Elliott, PJ. Linnoila, M., see Wozniak, K.M. (193) 253
Differential behavioural activation following intra-raphe infusion Lipkowski, A.W., see Lei, $.Z. (193) 209
of 5-HT,, receptor agonists (193) 351 Léfdahl, C.-G., see Tokuyama, K. (193) 35
Hildebrand, K.R., see Chandan, R. (193) 265 Létvall, J.0., see Tokuyama, K. (193) 35
Hisa, H., see Takahashi, T. (193) 315 Ludens, J.H., see Kolbasa, K.P. (193) 275
Hoffer, P., see Innis, R. (193) 249 Lund, A., see Tjolsen, A. (193) 193
Hole, K., see Tjolsen, A. (193) 193 Lutfy, K., see Yoburn, B.C. (193) 105
Holtzman, S.G., see Adams, J.U. (193) 67
Hitter, J.F. Malenka, R.C., see Baskys, A. (193) 131
Action of synthetic atrial natriuretic factor on contractility and Malison, R., see Innis, R. (193) 249
coronary perfusion in isolated working rat hearts (193) 127 Marsden, C.A., see Garratt, J.C. (193) 87
Mason, R., see Garratt, J.C. (193) 87
Imaizumi, Y., see Takeda, M. (193) 375 Masumura, H., Kunitada, S., Irie, K., Ashida, S. and Abe, Y.
A thromboxane A , synthase inhibitor, DP-1904, prevents rat renal
Innis, R., Zoghbi, S., Johnson, E., Woods, S., Al-Tikriti, M., Baldwin,
injury (193) 321
R., Seibyl, J., Malison, R., Zubal, G., Charney, D., Heninger, G.
Matias, A., Albino-Teixeira, A., Polénia, J. and Azevedo, I.
and Hoffer, P.
Long-term administration of 1,3-dipropyl-8-sulfophenylxanthine
SPECT imaging of the benzodiazepine receptor in non-human
primate brain with ['**1JRo 16-0154 (193) 249 causes arterial hypertension (193) 101
McCall, R.B., see Kolbasa, K.P. (193) 275
Irie, K., see Masumura, H. (193) 321
Iversen, S.D., see O'Neill, M.F. (193) 203 McCloskey, T.C., see Kehne, J.H. (193) 283
Millan, M.J. and Colpaert, F.C.
Methylenedioxymethamphetamine induces spontaneous tail-flicks
Jackson, H.C. and Nutt, D.J. in the rat via 5-HT,, receptors (193) 145
Effect of benzodiazepine and f-carboline antagonists and partial Mitchell, K.N., see Tam, S.W. (193) 121
agonists on loprazolam- and ZK 93423-induced hypothermia (193) Miwa, I., see Kato, K. (193) 185
179 Mizota, M., see Kato, K. (193) 185
Johnson, E., see Innis, R. (193) 249 Morikawa, M.., see Shibata, S. (193) 1
Johnson, M., Bush, L.G., Gibb, J.W. and Hanson, G.R.
Morton, I.K.M., see Hall, J.M. (193) 231
Blockade of the 3,4-methylenedioxymethamph Mosberg, H.I., see Wild, K.D. (193) 135
changes in neurotensin and dynorphin A systems (193) 367 Moser, P.C.
The effect of putative 5-HT,, receptor antagonists on 8-OH-
Kameyama, T., see Katoh, A. (193) 95 DPAT-induced hypothermia in rats and mice (193) 165
Karaki, H., see Shibata, S. (193) 1 Murakami, K., see Kato, K. (193) 185
Karbon, E.W., Naper, K. and Pontecorvo, M.J. Murakami, N., see Kato, K. (193) 185
(*H]DTG and (*H\ +)-3-PPP label pharmacologically distinct o
binding sites in guinea pig brain membranes (193) 21 Nabeshima, T., see Katoh, A. (193) 95
Kato, K., Nakayama, K., Ohta, M., Murakami, N., Murakami, K., Nadel, J.A., see Sommerhoff, C.P. (193) 153
Mizota, M., Miwa, I. and Okuda, J. Nagtegaal, J.E., see Doelman, C.J.A. (193) 117
Nakayama, K., Watanabe, N., Yamazawa, T., Takeshita, N., Tanaka, Shoji, T., see Adachi, H. (193) 57
Y. and Yanaihara, N. Shook, J.E., see Lemcke, P.K. (193) 109
Effects of porcine galanin on the mesenteric microcirculation and Soldani, G., see Chandan, R. (193) 265
arteriolar smooth muscle in the rat (193) 75 Sommerhoff, C.P., Krell, R.D., Williams, J.L., Gomes, B.C., Strim-
Nakayama, K., see Kato, K. (193) 185 pler, A.M. and Nadel, J.A.
Nandha, K.A., see Benito-Orfila, M.A. (193) 329 Inhibition of human neutrophil elastase by ICI 200,355 (193) 153
Naper, K., see Karbon, E.W. (193) 21 Spivak, C., see Shimada, S. (193) 123
Nicholson, C.D., see Fox, P.K. (193) 139 Sprong, R.C., see Doelman, C.J.A. (193) 117
Nordberg, G., see Gong, Q.-L. (193) 47 Srivastava, K.K., see Datta, M.C. (193) 173
Nutt, D_J., see Jackson, H.C. (193) 179 Strimpler, A.M., see Sommerhoff, C.P. (193) 153
Stutzmann, J.-M., Béhme, G.A., Gandolfo, G., Gottesmann, C., Laf-
Ogiwara, Y., see Furukawa, Y. (193) 217 forgue, J., Blanchard, J.-C., Laduron, P.M. and Lazdunski, M.
O'Grady, S.M., see Chandan, R. (193) 257 Riluzole prevents hyperexcitability produced by the mast cell
Ohno, M., Yamamoto, T. and Ueki, S. degranulating peptide and dendrotoxin I in the rat (193) 223
Effect of the «-receptor agonist, U-S0,488H, on cerebral ischemia-
induced impairment of working memory assessed in rats by a Takahashi, T., Hisa, H. and Satoh, S.
three-panel runway task (193) 357 Serotonin-induced renin release in the dog kidney (193) 315
Ohta, M., see Kato, K. (193) 185 Takeda, M., Imaizumi, Y. and Watanabe, M.
Okuda, J., see Kato, K. (193) 185 Effects of noradrenaline and heparin on outward current in single
O'Neill, M.F., Dourish, C.T. and Iversen, $.D. smooth muscle cells of the guinea-pig vas deferens (193) 375
Hypolocomotion induced by peripheral or central injection of Takeshita, N., see Nakayama, K. (193) 75
CCK in the mouse is blocked by the CCK, receptor antagonist Tam, S.W. and Mitchell, K.N.
devazepide but not by the CCK, receptor antagonist L-365,260 Neuropeptide Y and peptide YY do not bind to brain o and
(193) 203 phencyclidine binding sites (193) 121
Orlandi, M., see Giorgi, O. (193) 363 Tanaka, Y., see Nakayama, K. (193) 75
Tjolsen, A., Lund, A. and Hole, K.
Palfreyman, M.G., see Kehne, J.H. (193) 283 Antinociceptive effect of paracetamol in rats is partly dependent
Pélaprat, D., see Wang, H. (193) 341 on spinal serotonergic systems (193) 193
Pfister, S.L., see Rosolowsky, M. (193) 293 Tokuyama, K., Létvall, J.O., Léfdahl, C.-G., Barnes, PJ. and Chung,
Poldnia, J., see Matias, A. (193) 101 K.F.
Pontecorvo, M.J., see Karbon, E.W. (193) 21 Inhaled formoterol inhibits histamine-induced airflow obstruction
Porreca, F., see Wild, K.D. (193) 135 and airway microvascular leakage (193) 35
Post, R.M., see Weiss, S.R.B. (193) 159
Potter, E.K., Fuhlendorff, J. and Schwartz, T.W. Ueki, S., see Ohno, M. (193) 357
[Pro“|neuropeptide Y selectively identifies postjunctional-medi- Uhl, G., see Shimada, S. (193) 123
ated actions of neuropeptide Y in vivo in rats and dogs (193) 15 Uhién, S., see Wikberg, J.E.S. (193) 335
Unger, P., see Berkenboom, G. (193) 81
Rodrigues de Miranda, J.F., see Doelman, C.J.A. (193) 117
Roques, B.P., see Wang, H. (193) 341 Vanderah, T., see Wild, K.D. (193) 135
Rosolowsky, M., Pfister, S.L., Buja, L.M., Clubb, Jr., FJ. and Vanhove, A., see Wang, H. (193) 341
Campbell, W.B. Vasar, E., see Harro, J. (193) 379
Method of removal of aortic endothelium affects arachidonic acid
metabolism and vascular reactivity (193) 293 Wang, H., Pélaprat, D., Roques, B.P., Vanhove, A., Chi, Z.Q. and
Rosténe, W., see Wang, H. (193) 341 Rosténe, W.
{°H]Ohmefentanyl preferentially binds to p-opioid receptors but
Samanin, R., see Cervo, L. (193) 309 also labels o-sites in rat brain sections (193) 341
Satake, N., see Shibata, S. (193) 1 Washington, I., see Datta, M.C. (193) 173
Satoh, H. and Hashimoto, K. Watanabe, M., see Takeda, M. (193) 375
Comparative effects of a new calcium channel antagonist, Watanabe, N., see Nakayama, K. (193) 75
mepirodipine, on rabbit spontaneously beating sino-atrial node Weichman, B.M., see Berkenkopf, J.W. (193) 29
cells (193) 9 Weiss, S.R.B. and Post, R.M.
Satoh, S., see Takahashi, T. (193) 315 Contingent tolerance to carbamazepine: a peripheral-type benzo-
Sawada, T., see Shibata, S. (193) 1 diazepine mechanism (193) 159
Schwartz, T.W., see Potter, E.K. (193) 15 Whitten, J.P., see Kehne, J.H. (193) 283
Seibyl, J., see Innis, R. (193) 249 Wikberg, J.E.S., Uhlén, S. and Chhajlani, V.
Seybold, V.S., see Chandan, R. (193) 265 Medetomidine stereoisomers delineate two closely related subtypes
Shibata, S., Satake, N., Morikawa, M., Kown, S.-C., Karaki, H., of idazoxan (imidazoline) I-receptors in the guinea pig (193) 335
Kurahashi, K., Sawada, T. and Kodama, I. Wilcox, G.L., see Lei, $.Z. (193) 209
The inhibitory action of okadaic acid on mechanical responses in Wild, K.D., Vanderah, T., Mosberg, H.1. and Porreca, F.
guinea-pig vas deferens (193) 1 Opioid 8 receptor subtypes are associated with different potas-
Shimada, S., Spivak, C. and Uhl, G. sium channels (193) 135
Endothelin receptor: a profoundly desensitizing receptor ex- Williams, J.L., see Sommerhoff, C.P. (193) 153
pressed in Xenopus oocytes (193) 123 Woods, S., see Innis, R. (193) 249
Shoji, T. and Goto, K. Wozniak, K.M., Durcan, M.J. and Linnoila, M.
Comparison of the effects of endothelin-1 and Bay k 8644 on Is NAN-190 an effective antagonist of the hypothermia and hyper-
twitch contractions of the field-stimulated rat vas deferens (193) glycemia induced by the 5-HT,, receptor agonist, 8-OH-DPAT?
371 (193) 253
388
Yamamoto, T., see Ohno, M. (193) 357 Yoburn, B.C., Lutfy, K. and Candido, J.
Yamazawa, T., see Nakayama, K. (193) 75 Species differences in w- and 5-opioid receptors (193) 105
Yanaihara, N., see Nakayama, K. (193) 75
Yang, Z.-J. and Biggs, D.F.
Muscarinic receptors and parasympathetic neurotransmission in Zoghbi, S., see Innis, R. (193) 249
guinea-pig trachea (193) 301 Zubal, G., see Innis, R. (193) 249
European Journal of Pharmacology, 193 (1991) 389-397
© 1991 Elsevier Science Publishers B.V. 0014-/2919 /$9039.5 0
Key word index
Action potential (spontaneous) Antinociception
Mepirodipine; Verapamil; Diltiazem; Nifedipine; Sino-atrial node Paracetamol; 5-HT (5-hydroxytryptamine, serotonin); Noradrenaline;
cells (rabbit); Voltage-clamp (Satoh, H. (193) 9) Spinal cord (Tjolsen, A. (193) 193)
Adenosine Anxiety
1,3-Dipropyl-8-sulfophenylxanthine; Trophic effects; Arterial hyper- Vocalizations (ultrasonic); Benzodiazepines; 5-HT (5-hydroxy-
tension (Matias, A. (193) 101) tryptamine, serotonin); Glutamate; Glycine (Kehne, J.H. (193) 283)
Airway CCK receptors; CCK 4;C CK receptor antagonists; Exploratory activ-
Submucosal gland; Mucus; Serine protease; Elastin (insoluble); Neu- ity (Harro, J. (193) 379)
trophil elastase (EC 3.4.21.11) (human); Proteinase inhibitor; Hydro-
lase; (Bovine) (Sommerhoff, C.P. (193) 153) Aorta (rat)
Pentoxifylline; EDRF (endothelium-derived relaxing factor)
Airway obstruction (Berkenboom, G. (193) 81)
Asthma; Edema; Formoterol; Histamine; Salbutamol; (Guinea-pig)
(Tokuyama, K. (193) 35) Arachidonic acid
Denudation; Endothelium; Vascular reactivity; Methacholine;
Aldose reductase inhibitors Nitroprusside (Rosolowsky, M. (193) 293)
Diabetic neuropathy; Motor nerve conduction velocity; Sorbitol;
myo-Inositol (Kato, K. (193) 185) Arterial hypertension
Adenosine; 1,3-Dipropyl-8-sulfophenylxanthine; Trophic effects
Analgesia (Matias, A. (193) 101)
Morphine; Morphine-6-glucuronide; Morphine-3-glucuronide; Venti-
latory depression (Gong, Q.-L. (193) 47) Aspirin
5-Azacytidine; Hydroxyurea; Hemoglobin (proportions); Prostaglan-
Opioid receptors; DPDPE ({D-Pen’,D-Pen’ Jenkephalin); DAGO ({D- dins; (Rat) (Datta, M.C. (193) 173)
Ala’, NMePhe‘,Gly-ol* enkephalin); Tail flick; (Species comparison)
(Yoburn, B.C. (193) 105) Asthma
Airway obstruction; Edema; Formoterol; Histamine; Salbutamol;
Opioid receptors; Spinal cord; PLO17 (Tyr-Pro-N-MePhe-D-Pro- (Guinea-pig) (Tokuyama, K. (193) 35)
NH,); DPDPE (cyclic [D-Pen*,D-Pen*Jenkephalin); U-50,488H
(trans-3,4-dichloro-N-methyl-N-(2-(1-pyrrolidinyl)cyclohexy!)benzene- ATP
cetamine); Diarrhea; Gastrointestinal transit (Lemcke, P.K. (193) Okadaic acid; Vas deferens; Noradrenaline; KCl; BAY k 8644;
109) Nifedipine; Cytosolic Ca?* levels (Shibata, S. (193) 1)
ANF (atrial natriuretic factor) 5-Azacytidine
Heart (working, rat); Coronary perfusion; Contractility; Heart rate Aspirin; Hydroxyurea; Hemoglobin (proportions); Prostaglandins;
(Hiitter, J.F. (193) 127) (Rat) (Datta, M.C. (193) 173)
Anion secretion BAY k 8644
Muscarinic receptors; Cholinergic neurons; Jejunum (distal); (Rat) Okadaic acid; Vas deferens; Noradrenaline; ATP; KCl; Nifedipine;
(Chandan, R. (193) 265) Cytosolic Ca?* levels (Shibata, S. (193) 1)
Anticonvulsants Endothelin; Coronary blood flow; Myocardial function; (Pig) (Adachi,
Mast-cell degranulating peptide (MCD); Dendrotoxin I (DTX;); H. (193) 57)
Electroencephalography; Hippocampal slices; Antiglutamate; K*
channels (Stutzmann, J.-M. (193) 223) Endothelin-1; Vas deferens; (Rat) (Shoji, T. (193) 371)
Antidepressant activity Benzodiazepine receptors
Clonidine, a,-Adrenoceptors; (Rat) (Cervo, L. (193) 309) Single photon emission computed tomography (SPECT); Brain imag-
ing (Innis, R. (193) 249)
Antiglutamate
Mast-cell degranulating peptide (MCD); Dendrotoxin I (DTX,); Benzodiazepine receptors (peripheral-type)
Electroencephalography; Hippocampal slices; Anticonvulsants; K * Contingent tolerance; Carbamazepine; Kindling (Weiss, S.R.B. (193)
channels (Stutzmann, J.-M. (193) 223) 159)
390
Benzodiazepine receptor subtypes Brain imaging
Benzodiazepines; B-Carbolines; Body temperature; (Full and partial Benzodiazepine receptors; Single photon emission computed tomogra-
agonists); (Antagonists) (Jackson, H.C. (193) 179) phy (SPECT) (Innis, R. (193) 249)
Benzodiazepines Brain (rat)
B-Carbolines; Benzodiazepine receptor subtypes; Body temperature; (°HjOhmefentanyl; y-Opioid receptors; o-Receptors (Wang, H. (193)
(Full and partial agonists); (Antagonists) (Jackson, H.C. (193) 179) 341)
Pentylenetetrazol (convulsant); L-Lysine; GABA (y-aminobutyric Ca** -dependent K * currents
acid); GABA/benzodiazepine/chloride channel receptor complex; Heparin; Noradrenaline; Vas deferens; Smooth muscle cells (Takeda,
Neurotransmission modulator (Chang, Y.-F. (193) 239) M. (193) 375)
Anxiety; Vocalizations (ultrasonic); 5-HT (5-hydroxytryptamine, Carbamazepine
serotonin); Glutamate; Glycine (Kehne, J.H. (193) 283) Contingent tolerance; Benzodiazepine receptors (peripheral-type);
Kindling (Weiss, S.R.B. (193) 159)
Benzomorphan opiates
o Binding sites; 1,3-Di-o-tolylguanidine (DTG); Haloperidol; Dextro- B-Carbolines
methorphan; (+)-3-PPP ((+)-3-(3-hydroxyphenyl)-N-(1-propyl)- Benzodiazepines; Benzodiazepine receptor subtypes; Body tempera-
piperidine) (Karbon, E.W. (193) 21) ture; (Full and partial agonists); (Antagonists) (Jackson, H.C. (193)
179)
Binding sites
Idazoxan; Cerebral cortex; Ileum; Receptor subtypes; (Guinea-pig) CCK,
(Wikberg, J.E.S. (193) 335) CCK receptors; CCK receptor antagonists; Exploratory activity;
Anxiety (Harro, J. (193) 379)
o Binding sites
Benzomorphan opiates; 1,3-Di-o-tolylguanidine (DTG); Haloperidol; CCK receptor antagonists
Dextromethorphan; (+ )-3-PPP (( + )-3-(3-hydroxyphenyl)-N-(1-pro- CCK receptors; CCK, ; Exploratory activity; Anxiety (Harro, J. (193)
pyl)piperidine) (Karbon, E.W. (193) 21) 379)
Blood glucose CCK receptors
NAN-190; 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin); CCK,; CCK receptor antagonists; Exploratory activity; Anxiety
Body temperature; 5-HT,, receptors; (Mouse) (Wozniak, K.M. (193) (Harro, J. (193) 379)
253)
Cerebral cortex
Blood pressure Idazoxan; Binding sites; Ileum; Receptor subtypes; (Guinea-pig)
8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin); Heart rate; (Wikberg, J.E.S. (193) 335)
Tolerance; (Conscious rat) (Kolbasa, K.P. (193) 275)
Cerebral ischemia
BMY 7378 U-50,488H; «-Opioid receptor agonists; Runway tasks; Working
MDMA (3,4-methylenedioxymethamphetamine); 5-HT (5-hydroxy- memory; Reference memory (Ohno, M. (193) 357)
tryptamine, serotonin); 5-HT,, receptors; NAN-190 (Millan, M.J.
(193) 145) Cholecystokinin (CCK)
Locomotor activity; Devazepide; L-365,260; (Mouse) (O'Neill, M.F.
8-OH-DPAT-induced hypothermia; 5-HT,, receptors; NAN-190; WB (193) 203)
4101; (Species differences) (Moser, P.C. (193) 165)
Cholinergic neurons
Body temperature Anion secretion; Muscarinic receptors; Jejunum (distal); (Rat)
Benzodiazepines; 8-Carbolines; Benzodiazepine receptor subtypes; (Chandan, R. (193) 265)
(Full and partial agonists); (Antagonists) (Jackson, H.C. (193) 179)
Cholinergic neurotransmission
NAN-190; 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin); Muscarinic receptors; Pirenzepine; Gallamine; Trachea (guinea-pig)
Blood glucose; 5-HT,, receptors; (Mouse) (Wozniak, K.M. (193) 253) (Yang, Z.-J. (193) 301)
Bradykinin Clonidine, a,-Adrenoceptors
Bradykinin B, receptors; Duodenum (rat); K* channels; Peptidase Antidepressant activity; (Rat) (Cervo, L. (193) 309)
inhibitors; Lys,Lys-{Hyp’,Thi*,D-Phe’]BK (Hall, J.M. (193) 231)
Cl~ transport
Bradykinin B, receptors Na* transport; HCO, transport; Jejunum (distal) (Chandan, R.
Bradykinin; Duodenum (rat); K* channels; Peptidase inhibitors; (193) 257)
Lys,Lys-{Hyp’, Thi**,D-Phe’|]BK (Hall, J.M. (193) 231)
Contingent tolerance
Brain Benzodiazepine receptors (peripheral-type); Carbamazepine; Kindling
Polyamines; Polyamine binding; Polyamine uptake; Polyamine re- (Weiss, S.R.B. (193) 159)
lease; (Rat) (Gilad, G.M. (193) 41)
Contractility
Endothelin; Sarafotoxin; Desensitization; Xenopus oocytes; (Recep- Heart (working, rat); ANF (atrial natriuretic factor); Coronary perfu-
tor) (Shimada, S. (193) 123) sion; Heart rate (Hiitter, J.F. (193) 127)
INO 2628; K* channels; Muscarinic receptor; Sinoatrial pacemaker 1,3-Dipropy!-8-sulfophenylxanthine
activity; Heart (isolated, dog) (Furukawa, Y. (193) 217) Adenosine; Trophic effects; Arterial hypertension (Matias, A. (193)
101)
Coronary blood flow
Endothelin; BAY k 8644; Myocardial function; (Pig) (Adachi, H. Ditolyl-ortho guanidine (DTG)
(193) 57) o Ligands; Vas deferens; Phencyclidine (Fox, P.K. (193) 139)
Coronary perfusion Dopamine
Heart (working, rat); ANF (atrial natriuretic factor); Contractility; {Met* enkephalin; Opioid peptides; Stress; (Mouse) (Katoh, A. (193)
95)
Heart rate (Hiitter, J.F. (193) 127)
Cytosolic Ca?* levels Dynorphin A; MDMA (3,4-methylenedioxymethamphetamine);
NMDA (N-methyl-D-aspartate); Neurotensin (Johnson, M. (193) 367)
Okadaic acid; Vas deferens; Noradrenaline; ATP; KCl; BAY k 8644;
Nifedipine (Shibata, S. (193) 1)
DP-1904
Thromboxane A,; Thromboxane A, synthase inhibitor; Renal
DAGO ({D-Ala?,NMePhe*,Gly-ol®
ischemia; Hydronephrosis (Masumura, H. (193) 321)
Opioid receptors; DPDPE ({D-Pen*,D-Pen® Shasta Tail flick;
Analgesia; (Species comparison) (Yoburn, B.C. (193) 105) DPDPE (cyclic [D-Pen’,D-Pen* jenkephalin)
Opioid receptors; Spinal cord; PLO17 (Tyr-Pro-N-MePhe-D-Pro-
Dendrotoxin | (DTX;) NH); U-50,488H (trans-3,4-dichloro-N-me-(t2h-(y1l-p-yNr-
Mast-cell degranulating peptide (MCD); Electroencephalography; rolidinyl)cyclohexyl)benzeneacetamine); Diarrhea; Analgesia; Gastro-
Hippocampal slices; Anticonvulsants; Antiglutamate; K* channels intestinal transit (Lemcke, P.K. (193) 109)
(Stutzmann, J.-M. (193) 223)
DPDPE (|D-Pen*,D-Pen’ Jenkephalin)
Denudation Opioid receptors; DAGO ({D-Ala?,NMePhe*,Gly-ol® jenkephalin);
Endothelium; Arachidonic acid; Vascular reactivity; Methacholine; Tail flick; Analgesia; (Species comparison) (Yoburn, B.C. (193) 105)
Nitroprusside (Rosolowsky, M. (193) 293)
Duodenum (rat)
Dependence (acute) Bradykinin; Bradykinin B, receptors; K* channels; Peptidase inhibi-
tors; Lys,Lys-{Hyp’,Thi**,D-PheB’K (Hall, J.M. (193) 231)
Morphine; Naltrexone; Opioid peptides; Sensitization; Operant be-
haviour (Adams, J.U. (193) 67)
Dynorphin A
Dopamine; MDMA (3,4-methylenedioxymethamphetamine); NMDA
Desensitization
Endothelin; Sarafotoxin; Xenopus oocytes; Brain; (Receptor) (N-methyl-D-aspartate); Neurotensin (Johnson, M. (193) 367)
(Shimada, S. (193) 123)
Edema
Airway obstruction; Asthma; Formoterol; Histamine; Salbutamol:;
Devazepide
(Guinea-pig) (Tokuyama, K. (193) 35)
Cholecystokinin (CCK); Locomotor activity; L-365,260; (Mouse)
(O'Neill, M.F. (193) 203)
EDRF (endothelium-derived relaxing factor)
Pentoxifylline; Aorta (rat) (Berkenboom, G. (193) 81)
Dextromethorphan
o Binding sites; Benzomorphan opiates; 1,3-Di-o-tolylguanidine
Elastin (insoluble)
(DTG); Haloperidol; ( + )-3-PPP (( + )-3-(3-hydroxyphenyl)-N-(1-pro-
Airway; Submucosal gland; Mucus; Serine protease; Neutrophil elas-
pyl)piperidine) (Karbon, E.W. (193) 21)
tase (EC 3.4.21.11) (human); Proteinase inhibitor; Hydrolase; (Bovine)
(Sommerhoff, C.P. (193) 153)
Diabetic neuropathy
Aldose reductase inhibitors; Motor nerve conduction velocity; Sorbi-
Electroencephalography
tol; myo-Inositol (Kato, K. (193) 185) Mast-cell degranulating peptide (MCD); Dendrotoxin I (DTX, ); Hip-
pocampal slices; Anticonvulsants; Antiglutamate; K* channels
Diarrhea (Stutzmann, J.-M. (193) 223)
Opioid receptors; Spinal cord; PLO17 (Tyr-Pro-N-MePhe-D-Pro-
NH,); DPDPE (cyclic [D-Pen’,D-Pen’jenkephalin); U-50,488H Endothelin
(trans-3,4-dichloro-N-methyl-N-(2-(1-pyrrolidinyl)cyclohexyl)benzene- BAY k 8644; Coronary blood flow; Myocardial function; (Pig)
cetamine); Analgesia; Gastrointestinal transit (Lemcke, P.K. (193) (Adachi, H. (193) 57)
109)
Sarafotoxin; Desensitization; Xenopus oocytes; Brain; (Receptor)
Diltiazem (Shimada, S. (193) 123)
Mepirodipine; Verapamil; Nifedipine; Sino-atrial node cells (rabbit);
Action potential (spontaneous); Voltage-clamp (Satoh, H. (193) 9) Endothelin-1
BAY k 8644; Vas deferens; (Rat) (Shoji, T. (193) 371)
1,3-Di-o-tolylguanidine (DTG)
o Binding sites; Benzomorphan opiates; Haloperidol; Dextro- Endothelium
methorphan; (+)-3-PPP (( + )-3-(3-hydroxyphenyl)-N-(1-propyl)pi- Galanin; Mesenteric microcirculation; Smooth muscle (arteriolar);
peridine) (Karbon, E.W. (193) 21) K* channels (ATP-sensitive) (Nakayama, K. (193) 75)
392
Denudation; Arachidonic acid; Vascular reactivity; Methacholine; Heart (isolated, dog)
Nitroprusside (Rosolowsky, M. (193) 293) INO 2628; K* channels; Muscarinic receptor; Sinoatrial pacemaker
activity; Contractility (Furukawa, Y. (193) 217)
|Met* Jenkephalin
Opioid peptides; Dopamine; Stress; (Mouse) (Katoh, A. (193) 95) Heart rate
Heart (working, rat); ANF (atrial natriuretic factor); Coronary perfu-
Excitatory amino acids sion; Contractility (Hiitter, J.F. (193) 127)
Pentylenetetrazol; Kindling; MK-801; GABA (y-aminobutyric acid)
(Giorgi, O. (193) 363) 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin); Blood pres-
sure; Tolerance; (Conscious rat) (Kolbasa, K.P. (193) 275)
Exploratory activity
CCK receptors; CCK ,; CCK receptor antagonists; Anxiety (Harro, J. Heart (working, rat)
(193) 379) ANF (atrial natriuretic factor); Coronary perfusion; Contractility;
Heart rate (Hiitter, J.F. (193) 127)
Formoterol
Airway obstruction; Asthma; Edema; Histamine; Salbutamol; Hemoglobin (proportions)
(Guinea-pig) (Tokuyama, K. (193) 35) Aspirin; 5-Azacytidine; Hydroxyurea; Prostaglandins; (Rat) (Datta,
M.C. (193) 173)
Fundus stomach
in
Neuromedin U; Smooth muscle; Intestine; (Rat, Frog) (Benito-Orfila,
Ca**-dependent K* currents; Noradrenaline; Vas deferens; Smooth
M.A. (193) 329)
muscle cells (Takeda, M. (193) 375)
GABA /benzodiazepine /chloride channel receptor complex
Hippocampal slices
Pentylenetetrazol (convulsant); L-Lysine; Benzodiazepines; GABA
Mast-cell degranulating peptide (MCD); Dendrotoxin I (DTX,);
(y-aminobutyric acid); Neurotransmission modulator (Chang, Y.-F.
Electroencephalography; Anticonvulsants; Antiglutamate; K* chan-
(193) 239)
nels (Stutzmann, J.-M. (193) 223)
GABA (y-aminobutyric acid)
Histamine
Pentylenetetrazol (convulsant); L-Lysine; Benzodiazepines; GABA/
Airway obstruction; Asthma; Edema; Formoterol; Salbutamol;
benzodiazepine/chloride channel receptor complex; Neurotransmis-
(Guinea-pig) (Tokuyama, K. (193) 35)
sion modulator (Chang, Y.-F. (193) 239)
5-HT (5-hydroxytryptamine, se in)
Pentylenetetrazol; Kindling; MK-801; Excitatory amino acids (Giorgi,
MDMA (3,4-methylenedioxymethamphetamine); 5-HT,, receptors;
O. (193) 363)
BMY 7378; NAN-190 (Millan, M.J. (193) 145)
Galanin Paracetamol; Noradrenaline; Antinociception; Spinal cord (Tjolsen,
Mesenteric microcirculation; Smooth muscle (arteriolar); Endo- A. (193) 193)
thelium; K* channels (ATP-sensitive) (Nakayama, K. (193) 75)
Anxiety; Vocalizations (ultrasonic); Benzodiazepines; Glutamate;
Gallamine Glycine (Kehne, J.H. (193) 283)
Cholinergic neurotransmission; Muscarinic receptors; Pirenzepine;
Trachea (guinea-pig) (Yang, Z.-J. (193) 301) Kidney; Renin release; Methysergide; Ketanserin; Indomethacin
(Takahashi, T. (193) 315)
Gastrointestinal transit
Opioid receptors; Spinal cord; PLO17 (Tyr-Pro-N-MePhe-D-Pro- 5-HT receptor agonists
NH,); DPDPE (cyclic [D-Pen*,D-Pen°jenkephalin); U-50,488H
Locomotor activity; 8-OHDPAT 8-hydroxy-(di-N-propylamino)tetra-
(trans-3,4-dichloro-N-methyl-N-(2-(1-pyrrolidinyl)cyclohexyl)benzene- lin, Dorsal raphe nucleus; Median raphe nucleus, 5-HT,, receptor
cetamine); Diarrhea; Analgesia (Lemcke, P.K. (193) 109) agonists (Higgins, G.A. (193) 351)
Glutamate 5-HT,, receptors
Anxiety; Vocalizations (ultrasonic); Benzodiazepines; 5-HT (5-hy- MDMA (3,4-methylenedioxymethamphetamine); 5-HT (5-hydroxy-
droxytryptamine, serotonin); Glycine (Kehne, J.H. (193) 283) tryptamine, serotonin); BMY 7378; NAN-190 (Millan, M.J. (193)
145)
Glycine
Anxiety; Vocalizations (ultrasonic); Benzodiazepines; 5-HT (5-hy- 8-OH-DPAT-induced hypothermia; NAN-190; BMY 7378; WB 4101;
droxytryptamine, serotonin); Glutamate (Kehne, J.H. (193) 283) (Species differences) (Moser, P.C. (193) 165)
Haloperidol NAN-190; 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin);
o Binding sites; Benzomorphan opiates; 1,3-Di-o-tolylguanidine Body temperature; Blood glucose; (Mouse) (Wozniak, K.M. (193)
(DTG); Dextromethorphan; ( + )-3-PPP (( + )-3-(3-hydroxyphenyl)-N- 253)
(1-propyl)piperidine) (Karbon, E.W. (193) 21)
Hydrolase
HCO, transport Airway; Submucosal gland; Mucus; Serine protease; Elastin (insolu-
Na®* transport; Cl~ transport; Jejunum (distal) (Chandan, R. (193) ble); Neutrophil elastase (EC 3.4.21.11) (human); Proteinase inhibi-
257) tor; (Bovine) (Sommerhoff, C.P. (193) 153)
Hydronephrosis Kindling
DP-1904; Thromboxane A,; Thromboxane A, synthase inhibitor; Contingent tolerance; Benzodiazepine receptors (peripheral-type):
Renal ischemia (Masumura, H. (193) 321) Carbamazepine (Weiss, S.R.B. (193) 159)
Hydroxyurea Pentylenetetrazol; MK-801; GABA ( y-aminobutyric acid); Excitatory
Aspirin; 5-Azacytidine; Hemoglobin (proportions); Prostaglandins; amino acids (Giorgi, O. (193) 363)
(Rat) (Datta, M.C. (193) 173)
L-365,260
Idazoxan Cholecystokinin (CCK); Locomotor activity; Devazepide; (Mouse)
Binding sites; Cerebral cortex; Ileum; Receptor subtypes; (Guinea-pig) (O'Neill, M.F. (193) 203)
(Wikberg, J.E.S. (193) 335)
LeukotrieneB ,
lleum Pleurisy; Thromboxane B,; Lipoxygenase inhibitors; WY-50,295
Idazoxan; Binding sites; Cerebral cortex; Receptor subtypes; tromethamine (Berkenkopf, J.W. (193) 29)
(Guinea-pig) (Wikberg, J.E.S. (193) 335)
o Ligands
Indomethacin Vas deferens; Phencyclidine; Ditolyl-ortho guanidine (DTG) (Fox,
5-HT (5-hydroxytryptamine, serotonin); Kidney; Renin release; P.K. (193) 139)
Methysergide; Ketanserin (Takahashi, T. (193) 315)
Lipoxygenase inhibitors
INO 2628 Pleurisy; Leukotriene B,; Thromboxane B,; WY-50,295 tromethamine
K* channels; Muscarinic receptor; Sinoatrial pacemaker activity; (Berkenkopf, J.W. (193) 29)
Contractility; Heart (isolated, dog) (Furukawa, Y. (193) 217)
Locomotor activity
myo-Inositol
Cholecystokinin (CCK); Devazepide; L-365,260; (Mouse) (O'Neill,
Aldose reductase inhibitors; Diabetic neuropathy; Motor nerve con- M.F. (193) 203)
duction velocity; Sorbitol (Kato, K. (193) 185)
5-HT receptor agonists; 8-OHDPAT 8-hydroxy-(di-N-propylamino)-
Intestine
tetralin, Dorsal raphe nucleus; Median raphe nucleus, 5-HT,, recep-
Neuromedin U; Smooth muscle; Fundus stomach; (Rat, Frog) (Be-
tor agonists (Higgins, G.A. (193) 351)
nito-Orfila, M.A. (193) 329)
L-Lysine
Jejunum (distal)
Pentylenetetrazol (convulsant); Benzodiazepines; GABA (y-
Na” transport; Cl” transport; HCO, transport (Chandan, R. (193)
aminobutyric acid); GABA/benzodiazepine/chloride channel recep-
257)
tor complex; Neurotransmission modulator (Chang, Y.-F. (193) 239)
Anion secretion; Muscarinic receptors; Cholinergic neurons; (Rat) Lys,Lys-(Hyp’, Thi™*,D-Phe’ |BK
(Chandan, R. (193) 265)
Bradykinin; Bradykinin B, receptors; Duodenum (rat); K* channels;
Peptidase inhibitors (Hall, J.M. (193) 231)
K* channels
INO 2628; Muscarinic receptor; Sinoatrial pacemaker activity; Con-
tractility; Heart (isolated, dog) (Furukawa, Y. (193) 217) Mast-cell degranulating peptide (MCD)
Dendrotoxin I (DTX, ); Electroencephalography; Hippocampal slices;
Anticonvulsants; Antiglutamate; K * channels (Stutzmann, J.-M. (193)
Mast-cell degranulating peptide (MCD); Dendrotoxin I (DTX,);
223)
Electroencephalography; Hippocampal slices; Anticonvulsants; Anti-
glutamate (Stutzmann, J.-M. (193) 223)
MDMA (3,4-methylenedioxymethamph ine)
5-HT (5-hydroxytryptamine, serotonin); 5-HT,, receptors; BMY
Bradykinin; Bradykinin B, receptors; Duodenum (rat); Peptidase
inhibitors; Lys,Lys-{Hyp’,Thi>*,D-Phe’JBK (Hall, J.M. (193) 231) 7378, NAN-190 (Millan, M.J. (193) 145)
K* channels (ATP-sensitive) Dopamine; Dynorphin A; NMDA (N-methyl-D-aspartate); Neuro-
Galanin; Mesenteric microcirculation; Smooth muscle (arteriolar); tensin (Johnson, M. (193) 367)
Endothelium (Nakayama, K. (193) 75)
Median raphe nucleus, 5-HT,, receptor agonists
KCl Locomotor activity; 5-HT receptor agonists; 8-OHDPAT 8-hydroxy-
Okadaic acid; Vas deferens; Noradrenaline; ATP; BAY k 8644; (di-N-propylamino)tetralin, Dorsal raphe nucleus (Higgins, G.A. (193)
Nifedipine; Cytosolic Ca?* levels (Shibata, S. (193) 1) 351)
Ketanserin
5-HT (5-hydroxytryptamine, serotonin); Kidney; Renin release; Verapamil; Diltiazem; Nifedipine; Sino-atrial node cells (rabbit);
Methysergide; Indomethacin (Takahashi, T. (193) 315) Action potential (spontaneous); Voltage-clamp (Satoh, H. (193) 9)
Mesenteric microcirculation
5-HT (5-hydroxytryptamine, serotonin); Renin release; Methysergide; Galanin; Smooth muscle (arteriolar); Endothelium; K* channels
Ketanserin; Indomethacin (Takahashi, T. (193) 315) (ATP-sensitive) (Nakayama, K. (193) 75)
394
Methacholine 8-OH-DPAT-induced hypothermia; 5-HT,, receptors; BMY 7378;
Denudation; Endothelium; Arachidonic acid; Vascular reactivity; WB 4101; (Species differences) (Moser, P.C. (193) 165)
Nitroprusside (Rosolowsky, M. (193) 293)
8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin); Body temper-
Methysergide ature; Blood glucose; 5-HT,, receptors; (Mouse) (Wozniak, K.M.
5-HT (5-hydroxytryptamine, serotonin); Kidney; Renin release; (193) 253)
Ketanserin; Indomethacin (Takahashi, T. (193) 315)
Na®* transport
MK-801 Cl” transport; HCO, transport; Jejunum (distal) (Chandan, R.
Pentylenetetrazol; Kindling; GABA (y-aminobutyric acid); Excita- (193) 257)
tory amino acids (Giorgi, O. (193) 363)
Neurokinin
Morphine Substance P; Opioids (intrathecal); Spinal cord; Nociception (Lei,
Morphine-6-glucuronide; Morphine-3-glucuronide; Analgesia; Venti- S.Z. (193) 209)
latory depression (Gong, Q.-L. (193) 47)
Neuromedin U
Naltrexone; Opioid peptides; Sensitization; Dependence (acute); Op- Smooth muscle; Fundus stomach; Intestine; (Rat, Frog) (Benito-
erant behaviour (Adams, J.U. (193) 67) Orfila, M.A. (193) 329)
Morphine-3-glucuronide Y
Morphine; Morphine-6-glucuronide; Analgesia; Ventilatory depres- [Pro*™ neuropeptide Y; (Postjunctional); (In vivo); (Rat) (Potter, E.K.
sion (Gong, Q.-L. (193) 47) (193) 15)
Morphine-6-glucuronide Peptide YY; o Receptors; Phencyclidine receptors; (Binding) (Tam,
Morphine; Morphine-3-glucuronide; Analgesia; Ventilatory depres-
S.W. (193) 121)
sion (Gong, Q.-L. (193) 47)
[Pro™ |neuropeptide Y
Motor nerve conduction velocity
Neuropeptide Y; (Postjunctional); (In vivo); (Rat) (Potter, E.K. (193)
Aldose reductase inhibitors; Diabetic neuropathy; Sorbitol; myo-In- 15)
ositol (Kato, K. (193) 185)
Neurotensin
Mucus
Dopamine; Dynorphin A; MDMA (3,4-methylenedioxymethamphet-
Airway; Submucosal gland; Serine protease; Elastin (insoluble); Neu-
amine); NMDA (N-methyl-D-aspartate) (Johnson, M. (193) 367)
trophil elastase (EC 3.4.21.11) (human); Proteinase inhibitor; Hydro-
lase; (Bovine) (Sommerhoff, C.P. (193) 153)
Neurotransmission modulator
Pentylenetetrazol (convulsant); L-Lysine; Benzodiazepines; GABA
Muscarinic autoreceptors
(y-aminobutyric acid); GABA/benzodiazepine/chloride channel re-
Smooth muscle (tracheal); Muscarinic M, receptors; (Guinea-pig)
ceptor complex (Chang, Y.-F. (193) 239)
(Doelman, C.J.A. (193) 117)
Neutrophil elastase (EC 3.4.21.11) (human)
Muscarinic
Airway; Submucosal gland; Mucus; Serine protease; Elastin (insolu-
INO 2628; K* channels; Sinoatrial pacemaker activity; Contractility;
ble); Proteinase inhibitor; Hydrolase; (Bovine) (Sommerhoff, C.P.
Heart (isolated, dog) (Furukawa, Y. (193) 217)
(193) 153)
Muscarinic receptors
Anion secretion; Cholinergic neurons; Jejunum (distal); (Rat) Nifedipine
(Chandan, R. (193) 265) Okadaic acid; Vas deferens; Noradrenaline; ATP; KCl; BAY k 8644;
Cytosolic Ca?* levels (Shibata, S. (193) 1)
Cholinergic neurotransmission; Pirenzepine; Gallamine; Trachea
(guinea-pig) (Yang, Z.-J. (193) 301) Mepirodipine; Verapamil; Diltiazem; Sino-atrial node cells (rabbit);
Action potential (spontaneous); Voltage-clamp (Satoh, H. (193) 9)
Muscarinic M , receptors
Smooth muscle (tracheal); Muscarinic autoreceptors; (Guinea-pig) Nitroprusside
(Doelman, C.J.A. (193) 117) Denudation; Endothelium; Arachidonic acid; Vascular reactivity;
Methacholine (Rosolowsky, M. (193) 293)
Myocardial function
Endothelin; BAY k 8644; Coronary blood flow; (Pig) (Adachi, H. NMDA (N-methyl-D-aspartate)
(193) 57) Dopamine; Dynorphin A; MDMA (3,4-methylenedioxymethamphet-
amine); Neurotensin (Johnson, M. (193) 367)
Naltrexone
Morphine; Opioid peptides; Sensitization; Dependence (acute); Oper- Nociception
ant behaviour (Adams, J.U. (193) 67) Neurokinin; Substance P; Opioids (intrathecal); Spinal cord (Lei, S.Z.
(193) 209)
NAN-190
MDMA (3,4-mcthylenedioxymethamphetamine); 5-HT (5-hydroxy- Noradrenaline
tryptamine, serotonin); 5-HT,, receptors; BMY 7378 (Millan, M.J. Okadaic acid; Vas deferens; ATP; KCl; BAY k 8644; Nifedipine;
(193) 145) Cytosolic Ca?* levels (Shibata, S. (193) 1)