European Journal of Clinical Pharmacology Published by Springer-Verlag, starting with vol. 3, 1970/1971ff. Until vol. 8, 1975, subtitled Pharmacologia Clinica. Editors: Hans J. Dengler (since 1970), Luzius Dettli (1970-1990), Franz Gross (1970-1982), Ferenc Follath (1978-1989), Jeff K. Aronson (since 1983), R. Dahlqvist (since 1989), P. Dayer (since 1991). Continues: Pharmacologia Clinica, no. 481. Contents of Volume 59 - 2003/2004 Abdelrahman N, Kleinman Y, Rund D, ARNO Working Group — Clavenna A Bergmann J-F — Mahé I Daas N: Hyponatremia associated with the Artok L — Gelal A Bergstrom M, Grahnén A, Langstrém B: initiation of reboxetine therapy 177 Ashley E — McGready R Positron emission tomography Abraha I, Montedori A, Stracci F, Rossi M, Aursnes I — Nordeng H microdosing: a new concept with Romagnoli C: Statin compliance in the Aynacioglu AS — Giingér K application in tracer and early clinical drug Umbrian population 659 Azuma J — Otani M development 357 Adami J — Ulfvarson J Azuma J — Hanatani T Bernabei R — Onder G Adham IM — Hummers-Pradier E Bernspang E — Piitulainen E Adhikari M — Botha JH Babaoglu MO, Ocal T, Bayar B, Kayaalp SO, Berntorp E — Piitulainen E Adithan C, Gerard N, Naveen AT, Bozkurt A: Frequency and enzyme activity Bertele’ V — Garattini S Koumaravelou K, Shashindran CH, of the butyrylcholinesterase K-variant in a Berti A — Clavenna A Krishnamoorthy R: Genotype and allele Turkish population 875 Bertilsson L — Mirghani RA frequency of CYP2D6 in Tamilian Bae K-S — Kim M-K Bertilsson L — Kawanishi C population 517 Baghestanian M — Li S Bertilsson L — Aklillu E Adithan C, Gerard N, Vasu S, Balakrishnan Balakrishnan R — Adithan C Bertschy G —G ex-Fabry M R, Shashindran CH, Krishnamoorthy R: Balant LP — Gex-Fabry M Bettoncelli G — Mazzaglia G Allele and genotype frequency of CYP2C9 Balant-Gorgia AE — Gex-Fabry M Bjorklund H — Laine K in Tamilnadu population 707 Balkan D — Gelal A Bjorkman A — Li X-Q Affolter J — Leslie SJ Balocco-Mattavelli R — Reggi V Bjorkman S — Piitulainen E Agren H — Kawanishi C Balram C, Zhou Q, Cheung YB, Lee EJD: Boellner S — Oo C Ahnoff M — Eriksson UG CYP3A5*3 and *6 single nucleotide Bogaert M — Habraken H Ahokoski O — Laine K polymorphisms in three distinct Asian Bonati M — Clavenna A Aiemsa-ard J — Kukongviriyapan V populations 123 Bonati M — Reggi V Aklillu E, Carrillo JA, Makonnen E, Baltes E — Strolin Benedetti M Bondesson A, Midlév P, Eriksson T, Héglund Bertilsson L, Ingelman-Sundberg M: Banos J-E — Macedo A P: Pharmacotherapeutic interventions by a Xanthine oxidase activity is influenced by Barber N — Taxis K multi-speciality team: opinions of the environmental factors in Ethiopians 533 Baron G — Camus M general practitioners and nurses 65 AL-Shurbaji A — Lindh JD Bates CE — Currie GP Bongard V — Montastuc JL Al-Windi A: The validity of a questionnaire Bauer P — Joukhadar C Bonovas S — Tsantes AE on medicines used in health care practice: Bayar B — Babaoglu MO Borga O — Centerholt C comparison of a questionnaire and Begaud B, Fourrier A, Moore N, Moride Y: Boshier A, Wilton LV, Shakir SAW: computerized medical record survey 321 The delusion of reducing sample size 711 Evaluation of the safety of bupropion Alegret M — Roglans N Beijnen JH — de Maat MMR (Zyban) for smoking cessation from Allain H, Bentue-Ferrer D, Tarral A, Gandon Bekir N — Giingér K experience gained in general practice use in J-M: Effects on postural oscillation and Belowski D — Kowalski J England in 2000 767 memory functions of a single dose of Benaissa F — Mahmoudian M Botha JH, du Preez MJ, Adhikari M: zolpidem 5 mg, zopiclone 3.75 mg Benatar A — Cools F Population Pharmacokinetics of gentamicin and lormetazepam | mg in elderly healthy Benitez J — Morera T in South African newborns 755 subjects. A randomized, cross-over, double- Bennett K, Teeling M, Feely J: “‘Selective” Bougatef A — Cools F blind study versus placebo 179 switching from non-selective to selective Bozkurt A — Babaoglu MO Allegaert K, Tibboel D, Naulaers G, Tison D, non-steroidal anti-inflammatory Bramness JG, Skurtveit S, Morland J: Testing De Jonge A, Van Dijk M, Vanhole C, drugs 645 for benzodiazepine inebriation—relationship Devlieger H: Systematic evaluation of pain Bennett K — Williams D between benzodiazepine concentration and in neonates: effect on the number of Benowitz NL — Gelal A simple clinical tests for impairment in a intravenous analgesics prescribed 87 Bentue-Ferrer D — Allain H sample of drugged drivers 593 Allen PB — Morgan DR Berecz R — LLerena A Bredberg U — Eriksson UG Almeida L — Silveira P Berecz R, de la Rubia A, Dorado P, Breekveldt-Postma NS — Zwart-van Rijkom Almer S — Lindqvist M Fernandez-Salguero P, Dahl M-L, LLerena JEF Andersen T — Foss S A: Thioridazine steady-state plasma Breton I — Reggi V Anderson BJ — van der Marel CD concentrations are influenced by tobacco Brignoli O — Mazzaglia G Andersson TB — Li X-Q smoking and CYP2D6, but not by the Brockmdller J — Gaikovitch EA Andrade RJ — Lucena MI CYP2C9 genotype 45 BrockmOller J — Giingér K Angelberger P — Li S Berecz R — Dorado P Broeders MEAC, Molema J, Hop WCJ, Annas A — Lindh JD Berg S — Nilsson SE Vermue NA, Folgering HTM: Does the Anttila M — Laine K Bergman U — Ufer M inhalation device affect the bronchodilatory IV dose response curve of salbutamol in Cornuz J, Pinget C, Gilbert A, Paccaud F: Eichler H-G — Joukhadar C asthma and chronic obstructive pulmonary Cost-effectiveness analysis of the first-line Ekblom M — Centerholt C disease patients? 449 therapies for nicotine dependence 201 Ekl6f A-C, Thurelius A-M, Garle M, Rane A, Bruneel I Cools I Corradi L — Fogari R Sjéqvist F: The anti-doping hot-line, a Bruyn S Laine K Correa-Nunes A-M — Clark DWJ means to capture the abuse of doping Biicheler R— Gleiter CH Cosson V » EL Desoky ES agents in the Swedish society and a new Buysschaert M — Haufroid V Couturier A > Centerholt C service function in clinical Cricelli C » Mazzaglia G pharmacology 571 Camus M, Hennere G, Baron G, Peytavin G, Crommen J — Messin R EL Desoky ES, Fuseau E, Din Amry SE, Massias L, Mentre F, Farinotti R: Cullberg M — Fager G Cosson V: Pharmacokinetic modelling of Comparison of lithium concentrations in Currie GP, Bates CE, Lee DKC, Jackson CM, valproic acid from routine clinical data in red blood cells and plasma in samples Lipworth BJ: Effects of fluticasone plus Egyptian epileptic patients 783 collected for TDM. acute toxicity, or acute- salmeterol versus twice the dose of Eliasson E — Griskevicius L on-chronic toxicity 583 fluticasone in asthmatic patients 11 Ericsson O — Mirghani RA aputi AP — Mazzaglia G Eriksson T — Bondesson A arbonin P > Onder G Da’as N » Abdelrahman N Eriksson UG — Wolzt M aron J > Guedon-Moreau | Dahiya R > Sasaki M Eriksson UG — Fager G arraro M » Gheno G Dahl M-L > Lindh JD Eriksson UG, Bredberg U, Gislén K, arreer-Bruhwyler I - Messin R Dahl M-L > Griskevicius L Johansson LC, Frison L, Ahnoff M, arrillo JA Aklillu f Dahl M-L > Dorado P Gustafsson D: Pharmacokinetics and arrillo JA — Morera T Dahl M-L > Berecz R pharmacodynamics of ximelagatran, a ascorbi I Giingér K Dahlqvist R > Ucar M novel oral direct thrombin inhibitor, in ascorbi I Gaikovitch EA Dalhoff K > Kramer I young healthy male subjects 35 asteels A Cools | Damsgaard J > Foss S Eriksson-Lepkowska M > Fager G aulin C Mahe | Dane AL — Cooper KJ Eskild A — Nordeng H enterholt C, Ekblom M, Odergren T, Borga de Boer A — Tamminga WJ O, Popescu G, Molz K-H, Couturier A, de Jong THR — van der Marel CD Fager G, Cullberg M, Eriksson-Lepkowska Weil A: Pharmacokinetics and sedative De Jonge A — Allegaert K M, Frison L, Eriksson UG: effects in healthy subjects and subjects with de Moerloose P > Girardin I Pharmacokinetics and pharmacodynamics impaired liver function after continuous de la Rubia A — Berecz R of melagatran, the active form of the oral infusion of clomethiazole 117 de Leij LFMH — Tamminga WJ direct thrombin inhibitor ximelagatran, ‘erezo JG, Hristov RL, Sansuan AJC, de Maat MMR, ter Heine R, Mulder JW, are not influenced by acetylsalicylic Rodriguez JJV: Outcome trials of COX-2 Meenhorst PL, Mairuhu ATA, van Gorp acid 283 selective inhibitors: global safety evaluation ECM, Huitema ADR, Beijnen JH: Fagerstrom KO > Hasford J does not promise benefits 169 Incidence and risk factors for nevirapine- Falcao A > Silveira P esarl M Onder G associated rash 457 Famaey J-P — Messin R Chen X-P — Huang P De Ponti F — Poluzzi E Farinotti R — Camus M Chassany O Mahe I De Rosa M — Clavenna A Farre M — Macedo A Chernov JN — Gaikovitch EA de Zeeuw RA > Tamminga WJ Feely J — Bennett K Cheung YB — Balram C Debien B > Petitjeans F Feely J — Williams D Chiap P — Messin R Deligne J — Guedon-Moreau L Fenyvesi T — Messin R Chinitz DP — Kahan I Denig P — Pont LG Fernandez-Salguero P > Berecz R Cho D — McGready R Denvir MA — Leslie SJ Figueras A > Reggi V Cho J-Y — Kim M-K Desmeules J — Girardin F Filioussi K — Tsantes AE Cho T — McGready R Devlieger H > Allegaert K Fogari E — Fogari R Chung J-Y — Kim M-K Diekmann J > Holstein A Fogari R, Mugellini A, Zoppi A, Marasi G, Cinetto | Gheno G Din Amry SE — EL Desoky ES Pasotti C, Poletti L, Rinaldi A, Preti P: Clark DWJ, Correa-Nunes A-M, Edwards IR: Dixon LJ — Morgan DR Effects of valsartan compared with Signal that reboxetine use is linked with Dorado P, Berecz R, Norberto M-J, Yasar U, enalapril on blood pressure and cognitive symptoms of peripheral ischaemia Dahl M-L, LLerena A: CYP2C9 genotypes function in elderly patients with essential (Raynaud’s syndrome) 261 and diclofenac metabolism in Spanish hypertension 863 ‘lavenna A, Rossi E, Berti A, Pedrazzi G, De healthy volunteers 221 Fogari R, Preti P, Lazzari P, Corradi L, Zoppi Rosa M, Bonati M, and the ARNO Dorado P — Berecz R A, Fogari E, Mugellini A: Effect of Working Group: Inappropriate use of anti- Dorado P — LLerena A benazepril amlodipine combination on asthmatic drugs in the Italian paediatric Dorr A — Oo C fibrinolysis in hypertensive diabetic population 565 Drenth BFH Tamminga WJ patients 271 lemmesen JO > Kramer | du Preez MJ > Botha JH Folgering HTM — Broeders MEAC ‘ools F, Benatar A, Bruneel E, Theyskens C, Dubois C > Messin R ATTACC investigators + Quintana M Bougatef A, Casteels A, Vandenplas Y: A Duc M-I » Guedon-Moreau L Foss S, Schmidt JR, Andersen T, Rasmussen comparison of the pharmacokinetics of two Ducrocq D » Guedon-Moreau L JJ, Damsgaard J, Schaefer K, Munck LK: dosing regimens of cisapride and their Dudezak R >-Lis Congruence on medication between effects on corrected QT interval in patients and physicians involved in patient premature infants 17 Edner M — Quintana M course 84] ooper KJ, Martin PD, Dane AL, Warwick Edstein MD — McGready R Fourrier A — Begaud B MJ, Raza A, Schneck DW: The effect of Edwards IR — Clark DWJ Frétschl R — Gaikovitch EA erythromycin on the pharmacokinetics of Egberts ACG — Zwart-van Rijkom JEF Frison L — Fager G rosuvastatin 5] Egberts E-H — Holstein A Frison L — Eriksson UG Fuhr U, Harder S, Keller-Stanislawski B, Grenard A-S — Mahé I counter nicotine patch. Cohort study on Thiirmann P, Klinische Pharmakologie in Grind M — Wolzt M smoking cessation 443 Deutschland Verbund: Professor Norbert Griskevicius L, Yasar U, Sandberg M, Hashimoto Y > Taguchi M H. Rietbrock 497 Hidestrand M, Eliasson E, Tybring G, Hassan M — Griskevicius | Fukuda T — Hanatani T Hassan M, Dahl M-L: Bioactivation of Haufroid V, Ligocka D, Buysschaert M. Fukuda T — Otani M cyclophosphamide: the role of polymorphic Horsmans Y, Lison D: Cytochrome Funae Y — Hanatani T CYP2C enzymes 103 P4502E1 (CYP2E1) expression in Fuseau E — EL Desoky ES Gross AS — Hoskins JM peripheral blood lymphocytes: evaluation in Guedon-Moreau L, Ducrocq D, Duc M-F, hepatitis C and diabetes 29 Gaikovitch E — Oselin K Quieureux Y, L’Hote C, Deligne J, Caron J: Haustein K-O — Hasford J Gaikovitch EA, Cascorbi I, Mrozikiewicz Absolute contraindications in relation to Helin-Salmivaara A, Klaukka T, PM, Brockmdller J, Frétschl R, K6pke K, potential drug interactions in outpatient Huupponen R: Heavy users of non- Gerloff T, Chernov JN, Roots I: prescriptions: analysis of the first five steroidal anti-inflammatory drugs: a Polymorphisms of drug-metabolizing million prescriptions in 1999 689 nationwide prescription database study enzymes CYP2C9, CYP2C19, CYP2D6, Guedon-Moreau L, Ducrocq D, Duc M-F, in Finland 477 CYPIA1, NAT2 and of P-glycoprotein in a Quieureux Y, L’Hote C, Deligne J, Caron Hellgren | > Mirghani RA Russian population 303 J: Absolute contraindications in relation Hennere G > Camus M Galteau MM, Shamsa F: Urinary 6f- to potential drug interactions in Henricson K > Melander f hydroxycortisol: a validated test for outpatient prescriptions: analysis of the Herman ZS — Kowalski J evaluating drug induction or drug first five million prescriptions in Hess S — Hummers-Pradier E inhibition mediated through CYP3A in 1999 899 Hidalgo R — Lucena MI humans and in animals 713 Guénault N, Odou P, Robert H: Increase in Hidestrand M > Griskevicius L Gambassi G — Onder G dihydroxycarbamazepine serum levels in Hill G — Oo C Gandon J-M — Allain H patients co-medicated with oxcarbazepine Hjemdahl P — Quintana M Garattini S, Bertele’ V: Efficacy, safety and and lamotrigine 781 Hjorth Lassen L, Klingenberg Iversen H, cost of new drugs acting on the central Giingér K, Ozkur M, Cascorbi I, Brockmiller Olesen J: A dose-response study of nitric nervous system 79 J, Bekir N, Roots I, Aynacioglu AS: Beta 2- oxide synthase inhibition in different Garattini S, Bertele’ V: Efficacy, safety and adrenergic receptor polymorphism and vascular beds in man 499 cost of new cardiovascular drugs: a susceptibility to primary congenital and Hoéglund P — Holmquist I-B survey 701 primary open angle glaucoma 527 Hoéglund P — Bondesson A Garle M — Ekléf A-C Gustafsson D — Eriksson UG Holford NHG — van der Marel CD Geczy J — Messin R Gustafsson LL — Mirghani RA Holmquist I-B, Svensson B, Héglund P: Gelal A, Guven H, Balkan D, Artok L, Gustafsson LL — Li X-Q Psychotropic drugs in nursing- and old-age Benowitz NL: Influence of menthol on Guven H — Gelal A homes: relationships between needs of care caffeine disposition and pharmacodynamics Giizey C, Spigset O: B. Lerer (ed): and mental health status 669 in healthy female volunteers 417 Pharmacogenetics of psychotropic drugs Holstein A, Plaschke A, Hammer C, Egberts Gerard N — Adithan C Cambridge University Press, Cambridge, E-H: Characteristics and time course of Gerard N — Adithan C 2002, pp 446 (ISBN 0521806178) 85 severe glimepiride- versus glibenclamide- Gerloff T — Gaikovitch EA induced hypoglycaemia 91 Gervasini G — Morera T Haaijer-Ruskamp FM — Pont LG Holstein A, Plaschke A, Hammer C, Ptak M, Gex-Fabry M, Balant-Gorgia AE, Balant LP, Habraken H, Janssens I, Soenen K, van Driel Kuhn J, Kratzsch C, Diekmann J, Kleesiek Rudaz S, Veuthey J-L, Bertschy G: Time M, Lannoy J, Bogaert M: Pilot study on the K, Maurer HH, Egberts E-H: Hormonal course of clinical response to venlafaxine: feasibility and acceptability of academic counterregulation and consecutive relevance of plasma level and chirality 883 detailing in general practice 253 glimepiride serum concentrations during Ghannadan M — Li S Hall J — Johansson M severe hypoglycaemia associated with Gheno G, Cinetto L, Savarino C, Vellar S, Hammer C — Holstein A glimepiride therapy 747 Carraro M, Randon M: Variations of Hanatani T, Fukuda T, Onishi S, Funae Y, Holubec L — Mayer Jr O serum potassium level and risk of Azuma J: No major difference in inhibitory Hong K-S — Kim M-K hyperkalemia in inpatients receiving low- susceptibility between CYP2C9.1 Hop WCJ — Broeders MEAC molecular-weight heparin 373 and CYP2C9.3 233 Horiuchi R — Sekino K Gilbert A — Cornuz J Hanratty CG — Morgan DR Horsmans Y — Haufroid V Gilveray G — McGready R Hanninen J — Laine K Hoskins JM, Shenfield GM, Gross AS: Ginsberg A — McGready R Hansen DG, Sondergaard J, Vach W, Gram Concordance between proguanil Girardin F, Siegenthaler M, LF, Rosholm J-U, Kragstrup J: phenotype and CYP2C/9 genotype in de Moerloose P, Desmeules J: Rofecoxib Antidepressant drug use in general practice: Chinese 611 interaction with oral anticoagulant inter-practice variation and association Hristov RL > Cerezo JG acenocoumarol 489 with practice characteristics 143 Huang S-Z — Huang P Gislen K — Eriksson UG Hansen EH — Nielsen MW Huang P, Zhu B, Wang L-S, Gleiter CH, Biicheler R, Schwab M: Letter to Hansen EH — Melander E Ouyang D-S, Huang S-L, Chen X-P, the editor concerning Ufer et al: Eur J Clin Harder S — Fuhr L Zhou H-H: Relationship between CYP3A Pharmacol 58: Harris P — Shaw J activity and breast cancer susceptibility 779-783 (2003) 491 Hartikainen S, Klaukka T: Use of in Chinese Han women 471 Gonzalez AP — LLerena A psychotropics is high among very old Hubert P — Messin R Gonzalez A — van der Marel CD people 849 Huitema ADR — de Maat MMR Grahnen A — Bergstrém M Hasford J, Fagerstrom KO, Haustein K-O: / Hummers-Pradier E, Hess S, Adham IM, Gram LF — Hansen DG naturalistic cohort study on effectiveness, Papke T, Pieske B, Kochen MM: Graudins L — Shaw J safety and usage pattern of an over-the- Determination of bleeding risk using genetic markers in patients taking Klaukka T + Malm H Lee D-H — Kim M-K phenprocoumon 213 Klaukka T » Helin Salmivaara A Lee DKC — Currie GP Huupponen R Laine K Klaukka T + Hartikainen S Lee EJD — Balram C Huupponen R » Helin-Salmivaara A Kleesiek K — Holstein A Lee S-H — Kim M-K Kleinman Y — Abdelrahman N Lehtimaki T — Metso S Iga T — Sekino K Klingenberg Iversen H — Hjorth Lassen L Lernfelt B, Samuelsson O, Skoog I, Landahl Ingelman-Sundberg M Aklillu I Klinische Pharmakologie in Deutschland S: Changes in drug treatment in the elderly Inoue H Taguchi M Verbund — Fuhr U between 1971 and 2000 637 Kochen MM — Hummers-Pradier E Leslie SJ, Affolter J, Denvir MA, Webb DJ: Jackson P Johansson M Kollenz CJ — Joukhadar C Validation of laser Doppler flowmetry Jackson CM > Currie GP Koller E — Li S coupled with intra-dermal injection for Jacobsen G > Nordeng H Képke K — Gaikovitch EA investigating effects of vasoactive agents on Jambert Reggi \ Kopp C — Reggi V the skin microcirculation in man 99 Jang I-J — Kim M-K Kotegawa T — Oda M Leufkens HGM — Zwart-van Rijkom JEF Jansman FGA — van der Marel CD Koumaravelou K — Adithan C Li H-D — Peng W-X Janssens | > Habraken H Kowalski J, Okopien B, Madej A, Zielinski LiM—LiS Johansson B — Nilsson SE M, Belowski D, Kalina Z, Herman ZS: Li S, Dudezak R, Koller E, Baghestanian M, Johansson M, Hall J, Reith D, Effects of atorvastatin, simvastatin, Ghannadan M, Minar E, Pirich C, Jackson P, Tilyard M Trends in the use of and fenofibrate therapy on monocyte Angelberger P, Virgolini I, Li M, Valent P: inhaled corticosteroids for childhood chemoattractant protein-1 secretion Effect of statins on lipoprotein receptor asthma in New Zealand 483 in patients with hyperlipidemia 189 expression in cell lines from human mast Johansson LC — Eriksson UG Krahenbiihl S — Todesco L cells and basophils 507 Jonkman JHG Tamminga WJ Kragstrup J — Hansen DG Li X-Q, Bjérkman A, Andersson TB, Joukhadar C, Schenk B, Kaehler ST, Kollenz Kramer I, Dalhoff K, Clemmesen JO, Loft S, Gustafsson LL, Masimirembwa CM: CJ, Bauer P, Miller M, Eichler H-G: A Poulsen HE: Comparison of chlorzoxazone Identification of human cytochrome P4s0s replicate study design for testing one-sample methods to estimate CYP2E]1 that metabolise anti-parasitic drugs and bioequivalence: a case study on two activity in humans 775 predictions of in vivo drug hepatic desmopressin nasal spray Kratzsch C — Holstein A clearance from in vitro data 429 preparations 631] Krishnamoorthy R — Adithan C Ligocka D — Haufroid V Krishnamoorthy R — Adithan C Lilja JJ, Niemi M, Neuvonen PJ: Rifampicin Kaehler S1 Joukhadar C Kubota T — Sekino K reduces plasma concentrations of Kahan E, Kahan NR, Chinitz DP: Urinary Kuhn J — Holstein A celiprolol 819 tract infection in women—physician’s Kukongviriyapan V, Prawan A, Warasiha B, Lim H-S — Kim M-K preferences for treatment and adherence to Tassaneyakul W, Aiemsa-ard J: Lindblom B — Zackrisson A-L guidelines: a national drug utilization study Polymorphism of N-acetyltransferase | and Lindh JD, Annas A, Meurling L, Dahl M-L, in a managed care setting 663 correlation between genotype and AL-Shurbaji A: Effect of ketoconazole on Kahan NR Kahan I phenotype in a Thai population 277 venlafaxine plasma concentrations in Kahan T Quintana M Kungys G, Naujoks H. Wanner C: extensive and poor metabolisers of Kalina Z Kowalski J Pharmacokinetics of amlodipine in debrisoquine 401 Kameyama T Taguchi M hypertensive patients undergoing Lindqvist M, Almer S, Peterson C, Séderkvist Kampmann JP Melander | haemodialysis 291 P: Real-time RT-PCR methodology for Karjagin J, Pahkla R, Starkopf J: Kuwatani K — Oda M quantification of thiopurine Perioperative penetration of metronidazole methyltransferase gene expression 207 into muscle tissue: a microdialysis angstr6m B — Bergstr6m M Lipworth BJ — Sims EJ study 809 “Hote C — Guedon-Moreau L Lipworth BJ — Currie GP Kawanishi C, Lundgren S, Agren H, aguna JC — Roglans N Lison D — Haufroid V Bertilsson L: Increased incidence of aine K, De Bruyn S, Bjorklund H, Rourv J, Lithman T — Melander E CYP2D6 gene duplication in patients with Hanninen J, Scheinin H, Anttila M: Effect Liu B + Oo C persistent mood disorders: ultrarapid of the novel anxiolytic drug deramciclane LLerena A, Dorado P, Berecz R, Gonzalez metabolism of antidepressants as a cause of on cytochrome P45) 2D6 activity as AP, Petias-LLedo EM: Effect of CYP2D6 nonresponse. Ap ilot study 803 measured by desipramine and CYP2C9 genotypes on fluoxetine and Kayaalp SO — Babaoglu MO pharmacokinetics 893 norfluoxetine plasma concentrations during Keller-Stanislawski B Fuhr | aine K, Ahokoski O, Huupponen R, steady-state conditions 869 Kelly A — Williams D Hanninen J, Palovaara S, Ruuskanen J, LLerena A — Berecz R Keogh G — Shaw J Bjorklund H, Anttila M. Rouru J: Effect of LLerena A — Dorado P Kim K-A — Park J-¥ the novel anxiolytic drug deramciclane on Loft S — Kramer I Kim M-K, Cho J-Y, Lim H-S, Hong K-S, the pharmacokinetics and Looareesuwan S — McGready R Chung J-Y, Bae K-S, Oh D-S, Shin S-G pharmacodynamics of the CYP3A4 probe Loukopoulos D > Tsantes AE Lee S-H, Lee D-H, Min B, Jang I-J: Effect drug buspirone 761 Loureiro A > Silveira P of the CYP2D6 genotype on the Landahl S — Lernfelt B Lucena MI, Andrade RJ, Tognoni G, Hidalgo pharmacokinetics of tropisetron in healthy Landi F — Onder G R, Sanchez de la Cuesta F, the Spanish Korean subjects 111 Lannoy J — Habraken H Collaborative Study Group on Therapeutic Kimura K Sekino K Lapeyre-Mestre M Montastuc JI Management in Liver Diseases: Drug use Kjellman B Ulfvarson J Larsen N-E — Reuther LO for non-hepatic associated conditions in Kjerr A-C Quintana M Lazzari P — Fogari R patients with liver cirrhosis 71 Lundgren S — Kawanishi C Famaey J-P, Géczy J: A pilot double-blind Mulder JW — de Maat MMR Luurila H — Ucar M randomized placebo-controlled study of Munck LK -— Foss § molsidomine 16 mg once-a-day in patients Macedo A, Farré M, Bajios J-E: Placebo suffering from stable angina pectoris: Naik M + Nygaard HA effect and placebos: what are we talking correlation between efficacy and over time Nadaud J > Petitjeans F about? Some conceptual and historical plasma concentrations 227 Nakano S — Oda M considerations 337 Messori A — Pelagotti F Naohara M — Otani M Machado R — Silveira P Metso S, Ylitalo R, Nikkila M, Wuolijoki E, Nardi R — Mazzaglia G Madej A — Kowalski J Ylitalo P, Lehtimaki T: The effect of long- Naujoks H > Kungys G Mahe I, Chassany O, Grenard A-S, Caulin C, term microcrystalline chitosan therapy on Nasman P > Quintana M Bergmann J-F: Methadone and edema: a plasma lipids and glucose concentrations in Naulaers G » Allegaert K case-report and literature review 923 subjects with increased plasma total Naveen AT + Adithan C Mahmoudian M, Mehrpour M, Benaissa F, cholesterol: a randomised placebo- Nesheim B-I » Nordeng H Siadatpour Z: A preliminary report on the controlled double-blind crossover trial in Neuvonen M >» Ucar M application of noscapine in the treatment of healthy men and women 741 Neuvonen PJ > Lilja JJ stroke 579 Meurling L — Lindh JD Neuvonen PJ > Ucar M Maia J — Silveira P Midlév P — Bondesson A Neuvonen PJ + Malm H Mairuhu ATA — de Maat MMR Min B — Kim M-K Nicolas J-M — Strolin Benedetti M Makonnen E — Aklillu E Minar E > LiS Nielsen GL — Moller LR Malm H, Martikainen J, Klaukka T, Mirghani RA, Ericsson O, Tybring G, Nielsen MW, Hansen EH, Rasmussen NK: Neuvonen PJ: Prescription drugs during Gustafsson LL, Bertilsson L: Quinine 3- Prescription and non-prescription medicine pregnancy and lactation—a Finnish register- hydroxylation as a biomarker reaction for use in Denmark: association with socio- based study 127 the activity of CYP3A4 in man 23 economic position 677 Marasi G — Fogari R Mirghani RA, Hellgren U, Bertilsson L, Niemi M — Lilja JJ Martikainen J — Malm H Gustafsson LL, Ericsson O: Metabolism Nikkila M — Metso S Martin PD — Cooper KJ and elimination of quinine in healthy Nilsson SE, Johansson B, Takkinen S, Berg S, Masimirembwa CM — Li X-Q volunteers 423 Zarit S, McClearn G, Melander A: Does Massias L — Camus M Mizukami A — Taguchi M aspirin protect against Alzheimer’s Maune H — Otani M Mjérndal T — Ucar M dementia? A study in a Swedish population- Maurer HH — Holstein A Moller LR, Nielsen GL, Olsen ML, Thulstrup based sample aged 280 years 313 Mayer Jr O, Simon J, Holubec L, Pikner R, AM, Mortensen JT, Sorensen HT: Hospital Nissen A — Melander E Subrt I: Fenofibrate-induced discharges and 30-day case fatality for drug Norberto M-J — Dorado P hyperhomocysteinemia may be prevented poisoning: a Danish population-based Nordeng H, Eskild A, Nesheim B-I, Aursnes by folate co-administration 367 study from 1979 to 2002 with special I, Jacobsen G: Guidelines for iron Mazzaglia G, Caputi AP, Rossi A, Bettoncelli emphasis on paracetamol 911 supplementation in pregnancy: compliance G, Stefanini G, Ventriglia G, Nardi R, Molema J — Broeders MEAC among 431 parous Scandinavian Brignoli O, Cricelli C: Exploring patient- MOlstad S — Melander E women 163 and doctor-related variables associated with Molz K-H — Centerholt C Nosten F — McGready R antibiotic prescribing for respiratory Montanaro N — Poluzzi E Novell F — Roglans N infections in primary care 651 Montane E — Reggi V Nozawa T — Taguchi M McClearn G — Nilsson SE Montastuc JL, Bongard V, Lapeyre-Mestre Nygaard HA, Naik M, Ruths S, McGready R, Stepniewska K, Seaton E, Cho M: Perception of the risk of gastrointestinal Straand J: Nursing-home residents and T, Cho D, Ginsberg A, Edstein MD, Ashley adverse drug reactions with non-steroidal their drug use: a comparison between E, Looareesuwan S, White NJ, Nosten F: anti-inflammatory drugs (including coxibs): mentally intact and mentally impaired Pregnancy and use of oral contraceptives differences among general practitioners, residents. The Bergen district nursing home reduces the biotransformation of proguanil gastroenterologists and (BEDNURS) study 463 to cycloguanil 553 rheumatologists 685 McGready R, Stepniewska K, Edstein MD, Montedori A — Abraha I Cho T, Gilveray G, Looareesuwan S, White Moore N — Bégaud B Ocal T — Babaoglu MO NJ, Nosten F: The pharmacokinetics of Morland J — Bramness JG Oda M, Kotegawa T, Tsutsumi K, Ohtani Y atovaquone and proguanil in pregnant Morera T, Gervasini G, Carrillo JA, Benitez J: Kuwatani K, Nakano S: The effect of women with acute falciparum malaria Early detection of drug interactions itraconazole on the pharmacokinetics and McVeigh GE — Morgan DR utilizing a computerized drug prescription pharmacodynamics of bromazepam in Meenhorst PL — de Maat MMR handling system focus on cerivastatin healthy volunteers 615 Mehrpour M — Mahmoudian M gemfibrozil 917 Odergren T > Centerholt C Melander A — Melander E Morgan DR, Silke B, Dixon LJ, Allen PB, Odou P + Guenault N Melander A — Nilsson SE Hanratty CG, McVeigh GE: Central Oh D-S > Kim M-K Melander E, Nissen A, Henricson K, Merlo J, and peripheral haemodynamic effects Ohtani Y >» Oda M Molstad S, Kampmann JP, Lithman T, of L-NAME infusion in healthy Okada Y > Sekino K Hansen EH, Melander A: Utilisation of volunteers 195 Okopien B > Kowalski J antibiotics in young children: opposite Moride Y — Begaud B Olesen J » Hjorth Lassen L relationships to adult educational levels in Mortensen JT — Moller LR Olive F — Petitjeans F Danish and Swedish counties 331 Motola D — Poluzzi E Olsen ML — Moller LR Mentre F — Camus M Mrozikiewicz PM — Gaikovitch EA on behalf of investigators of the GIFA Study Merlo J — Melander E Mrozikiewicz PM — Oselin K + Onder G Messin R, Fenyvesi T, Carreer-Bruhwyler F, Mugellini A — Fogari R Crommen J, Chiap P, Hubert P, Dubois C, Miiller M — Joukhadar C Vill on behalf of The International Comparative Plaschke A — Holstein A Roglans N, Vazquez-Carrera M, Alegret M, Study On Drug Information (ICSODI) Pluim MAL — van der Marel CD Novell F, Zambon D, Ros E, Laguna JC, Collaborative Group — Reggi V Poletti L — Fogari R Sancliez RM: Fibrates modify the Onder G, Landi F, Cesari M, Gambassi G, Poluzzi E, Motola D, Silvani C, De Ponti F, expression of key factors involved in Carbonin P, Bernabei R, on behalf of Vaccheri A, Montanaro N: Prescriptions of bile-acid synthesis and biliary-lipid investigators of the GIFA Study: antidepressants in primary care in Italy: secretion in gallstone patients 855 Inappropriate medication use among pattern of use after admission of selective Romagnoli C — Abraha I hospitalized older adults in Italy: results serotonin reuptake inhibitors for Roots | — Giingér K from the Italian Group of reimbursement 825 Roots I — Oselin K Pharmacoepidemiology in the Elderly 157 Pont LG, Denig P, van der Molen T, van der Roots I — Gaikovitch EA Onishi S Hanatani 1 Veen WJ, Haaijer-Ruskamp FM: Validity Ros E — Roglans N Oo C, Hill G, Dorr A, Liu B, Boellner S, of 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Kimura K, Iga T: observationsatuld y 905 Drug Information (ICSODI) Collaborative Effect of the single CYP2C9*3 allele on Peng W-X, Li H-D, Zhou H-H: Effect of Group: Prescribing information in 26 pharmacokinetics and pharmacodynamics daidzein on CYP1A2 activity countries: a comparative study 263 oflosartanin healthy Japanese subjects 589 and pharmacokinetics of theophylline Rehnqvist N — Quintana M Senda C — Otani M in healthy volunteers 237 Reilly M — Ulfvarson J Shakir SAW — Boshier A Perez JP » Petitjeans I Reith D — Johansson M Shamsa F — Galteau MM Perks | » Shaw J Remon JP — Risha PG Shashindran CH — Adithan C Peterson C > Lindqvist M Reuther LO, Vainer B, Sonne J, Larsen N-E: Shaw J, Harris P, Keogh G, Graudins L, Petitjeans F, Nadaud J, Perez JP, Debien B, Thiopurine methyltransferase (TPMT) Perks E, Thomas PS: Error reduction: Olive F, Villevieille T, Pats B: A case of genotype distribution in azathioprine- academic detailing as a method to reduce rhabdomyolysis with fatal outcome after a tolerant and -intolerant patients with incorrect prescriptions 697 treatment with levofloxacin 779 various disorders. The impact of TPMT Shenfield GM — Hoskins JM Peytavin G — Camus M genotyping in predicting toxicity 797 Shin S-G — Kim M-K Pieske B — Hummers-Pradier I Rinaldi A — Fogari R Siadatpour Z — Mahmoudian M Piitulainen | Bernspang E, Bjorkman S, Risha PG, Vervaet C, Vergote G, Van Bortel Siegenthaler M — Girardin F Berntorp I Tailored pharmacokinetic L, Remon JP: Drug formulations intended Silke B — Morgan DR dosing allows self-administration and for the global market should be tested for Silvani C — Poluzzi E reduces the cost of IV augmentation stability under tropical climatic Silveira P, Vaz-da-Silva M, Almeida L, Maia therapy with human x -antitrypsin 151 conditions 135 J, Faledo A, Loureiro A, Torrao L, Pikner R Mayer Jr O Robert H — Gueénault N Machado R, Wright L, Soares-da-Silva P: Pinget C > Cornuz J Rocchi F — Reggi V Pharmacokinetic-pharmacodynamic Pirich C »>LiS Rodriguez JJV — Cerezo JG interaction between BIA 3-202, a novel COMT inhibitor, and levodopa Thurelius A-M — Ekl6éf A-C Vellar S + Gheno G benserazide 603 Tibboel D — van der Marel CD Ventriglia G — Mazzaglia G Simon J — Mayer Jr O Tibboel D — Allegaert K Vergote G — Risha PG Sims EJ, Lipworth BJ: Concomitant Tison D — Allegaert K Vermue NA — Broeders MEAC occasional use of salbutamol influences Todesco L, Térék M, Krahenbiihl S, Wenk Vervaet C — Risha PG bronchoprotective responsiveness afforded M: Determination of -3858G—A and Veuthey J-L — Gex-Fabry M by formoterol in patients with the glycine- -164C-A genetic polymorphisms of Villevieille T — Petitjeans F 16 genotype 791 CYP1A2 in blood and saliva by rapid allelic Virgolini | — LiS Sj6qvist F + Eklof A-C discrimination: large difference in the Vlachou A — Tsantes AE Sjéqvist F: EACPT 2001 in Odense was a prevalence of the —3858G-A mutation von Bahr C — Ulfvarson J success: now we are heading to between Caucasians and Asians 343 Vranckx S — Tamminga WJ Istanbul 77 Tognoni G — Lucena MI Skoog I — Lernfelt B Torrao L — Silveira P Skurtveit S — Bramness JG Trippoli S — Pelagotti F Wahlander K > Wolzt M Wang L-S > Huang P Soares-da-Silva P — Silveira P Tsantes AE, Tassiopoulos ST, Wanner C - Kungys G Soenen K — Habraken H Papadhimitriou SI, Bonovas S, Poulakis N, Warasiha B — Kukongviriyapan V Sollevi A — Quintana M Vlachou A, Filioussi K, Loukopoulos D: Ward P — Oo C Sonne J — Reuther LO Theophylline treatment may adversely Waring WS: The role of pharmacotherapy in Spigset O — Giizey C affect the anoxia-induced erythropoietic assisting smoking cessation 35] Starkopf J — Karjagin J response without suppressing Warwick MJ — Cooper KJ Stefanini G — Mazzaglia G erythropoietin production 379 Stepniewska K — McGready R Tsutsumi K — Oda M Webb DJ — Leslie SJ Weil A — Centerholt C Straand J — Nygaard HA Tybring G — Mirghani RA Stracci F — Abraha | Tybring G — Griskevicius L Wemer J — Tamminga WJ Wenk M — Todesco L Strolin Benedetti M, Whomsley R, Nicolas J- White NJ — McGready R M, Young C, Baltes E: Pharmacokinetics Ufer M, Bergman U: Off-label paediatric Whomsley R — Strolin Benedetti M and metabolism of '*C-levetiracetam, a new prescribing in Stockholm (Sweden): a Williams D, Teljeur C, Bennett K, Kelly A, antiepileptic agent, in healthy response to a letter to the editor 493 Feely J: Influence of material deprivation volunteers 621 Jcar M, Neuvonen M, Luurila H, Dahlqvist on prescribing patterns within a deprived Subrt | — Mayer Jr O R, Neuvonen PJ, Mjérndal T: population 559 Svensson B — Holmquist I-B Carbamazepine markedly reduces serum Wilton LV — Boshier A Svensson M — Wolzt M concentrations of simvastatin and Wollbratt M — Wolzt M Swahn E — Quintana M simvastatin acid 879 Wolzt M, Wollbratt M, Svensson M, \fvarson J, Adami J, Wredling R, Kjellman Wahlander K, Grind M, Eriksson UG: T6r6k M — Todesco L B, Reilly M, von Bahr C: Controlled Consistent pharmacokinetics of the oral Taguchi M, Nozawa T, Kameyama T, Inoue withdrawal of selective serotonin reuptake direct thrombin inhibitor ximelagatran in H, Takesono C, Mizukami A, Hashimoto inhibitor drugs in elderly patients in nursing Y: Effect of CYP2D6*10 on homes with no indication of patients with nonvalvular atrial fibrillation and in healthy subjects 537 pharmacokinetic variability of routinely depression 735 administered metoprolol in middle-aged Wredling R — Ulfvarson J Wright L — Silveira P and elderly Japanese patients 385 Vazquez-Carrera M — Roglans N Takesono C — Taguchi M Vacca F — Pelagotti F Wuolijoki E — Metso S Takkinen S — Nilsson SE Vaccheri A — Poluzzi E Tamminga WJ, Wemer J, Oosterhuis B, de Vach W — Hansen DG Yamada Y » Sekino K Boer A, Vranckx S, Drenth BFH, de Zeeuw Vainer B — Reuther LO Yamamoto I » Otani M RA, de Leij LFMH, Jonkman JHG: Valent P — LiS Yamamoto K > Sekino K Polymorphic drug metabolism (CYP2D6) Van Bortel L — Risha PG Yasar U - Griskevicius L and utilisation of psychotropic drugs in van den Anker JN — van der Marel CD Yasar U » Dorado P hospitalised psychiatric patients: a van der Marel CD, Anderson BJ, van Lingen Ylitalo P + Metso S retrospective study 57 RA, Holford NHG, Pluim MAL, Jansman Young C > Strolin Benedetti M Tanaka Y — Sasaki M FGA, van den Anker JN, Tibboel D: Tarral A — Allain H Paracetamol and metabolite Tassaneyakul W — Kukongviriyapan V pharmacokinetics in infants 243 Zackrisson A-L, Lindblom B: Identification of Tassiopoulos ST — Tsantes AE van der Marel CD, Anderson BJ, Pluim CYP2D6 alleles by single nucleotide Taxis K, Barber N: Incidence and severity of MAL, de Jong THR, Gonzalez A, Tibboel polymorphism analysis using intravenous drug errors in a German D: Acetaminophen in cerebrospinal fluid in pyrosequencing 521 hospital 815 children 297 Zambon D — Roglans N Teeling M — Bennett K van der Molen T + Pont LG Zarit S — Nilsson SE Teljeur C — Williams D van der Veen WJ — Pont LG Zhou H-H — Huang P ter Heine R — de Maat MMR Van Dijk M — Allegaert K Zhou H-H — Peng W-X Thirmann P — Fuhr U van Driel M — Habraken H Zhou Q — Balram C the Spanish Collaborative Study Group on van Gorp ECM — de Maat MMR Zhu B — Huang P Zielinski M — Kowalski J Therapeutic Management in Liver Diseases van Lingen RA — van der Marel CD — Lucena MI Vandenplas Y — Cools F Zoppi A — Fogari R Theyskens C — Cools F Vanhole C — Allegaert K Thomas PS — Shaw J Vasu S — Adithan C Indexed in/abstracts by Current Contents and Thulstrup AM — Moller LR Vaz-da-Silva M — Silveira P Index Medicus