Table Of Content

Contents of Volume 22 Number 1, January 1992 Review: HLA and disease: from epidemiology Skin blood cell flux in insulin-dependent to immunotherapy diabetic subjects in relation to retinopathy or R. R. P. de Vries incipient nephropathy A. J. H. M. Houben, N. C. Schaper, Review: Haemodynamics effects of H2-receptor D. W. Slaaf, G. J. Tangelder and antagonists A. C. Nieuwenhuijzen Kruseman H. Hinrichsen, A. Halabi and W. Kirch Instructions to authors Hypersensitivity to ADP of platelets from diabetic rats associated with enhanced fibrinogen binding P. D. Winocour, D. W. Perry and Number 2, February 1992 R. L. Kinlough- Rathbone Transport of L-leucine hydroxy analogue and Vasoactive intestinal polypeptide (VIP) and L-lactate in human small intestinal brush peptide histidine methionine (PHM) in human border membrane vesicles penile corpus cavernosum tissue and circumflex veins: localization and in vitro effects M. Friedrich, H. Murer, E. Sterchi and H. J. Kirkeby, J. Fahrenkrug, F. Holmquist and E. G. Berger B. Ottesen Plasma homocysteine before and after methionine loading with regard to age, gender, Glucagon-independent renal hyperaemia and and menopausal status hyperfiltration after an oral protein load in A. Andersson, L. Brattstrém, B. Israelsson, Child A liver cirrhosis A. Isaksson, A. Hamfelt and B. Hultberg N. G. De Santo, P. Anastasio, C. Loguercio, C. del Vecchio Blanco, G. Capasso, S. Coppola, Apolipoprotein C-II deficiency syndrome due L. Bellini, G. Spagnuolo, P. Federico, R. Alfieri, to apo C-I Hamburg: Clinical and biochemical A. Lombardi, M. Policastro and A. Perrelli features and HpAlI restriction enzyme polymorphism The influence of erythrocyte shape on F. U. Beil, S. S. Fojo, H. B. Brewer Jr, suspension viscosities H. Greten and U. Beisiegel W. H. Reinhart, M. Singh-Marchetti and P. W. Straub Plasma triglyceride and low density lipoprotein metabolism Clinical pharmacokinetic studies ofa human M. J. Caslake, C. J. Packard, J. J. Series, haemopoietic growth factor, GM-CSF B. Yip, M. M. Dagen and J. Shepherd D. Hovgaard, B. T. Mortensen, S. Schifter and N. I. Nissen Erythrocytes with covalently bound fibrinogen as a cellular replacement for the treatment of Sodium-lithium countertransport kinetics in thrombocytopenia normal and hypertensive human pregnancy G. Agam and A. A. Livne P. A. Rutherford, T. H. Thomas, S. MacPhail and R. Wilkinson Trichosanthin treatment of HIV-induced immune dysregulation Effect of endothelin-1 in man: pretreatment R. A. Mayer, P. A. Sergios, K. Coonan and with nifedipine, with indomethacin and with L. O’Brien cyclosporine A H. Vierhapper, O. F. Wagner, P. Nowotny and The ontogeny and site of intestinal lipid and W. Waldhdusl lipoprotein synthesis M. Mehran, L. Thibault, P. Russo, C. Garofalo Somatostatin does not block the effect of and E. Levy vasoactive intestinal peptide in bile secretion in man The characterization of a mutation of the 3’ B. Nyberg, B. Angelin and K. Einarsson flanking sequence of the «)-antitrypsin gene CONTENTS commonly associated with chronic obstructive Increase of glomerular-filtration rate and renal airways disease plasma flow by insulin-like growth factor-| K. Morgan, G. Scobie and N. Kalsheker during euglycaemic clamping in anaesthetized rats Different immunologic properties of the U. Baumann, T. Eisenhauer and H. Hartmann globular NCI domain of collagen type IV isolated from various human basement Effect of endothelin on normal and diseased membranes human coronary arteries M. Weber and O. Pullig A. H. Chester, G. S. O'Neil, S. P. Allen, T. N. Luu, S. Tadjkarimi and M. H. Yacoub Number 3, March 1992 Hyperhomocysteinaemia in stroke: prevalence, cause, and relationships to type of stroke and Relationship of insulin clearance and secretion stroke risk factors to insulin sensitivity in non-diabetic Mexican L. Brattstrém, A. Lindgren, B. Israelsson, Americans M. R. Malinow, B. Norring, B. Upson and S. M. Haffner, M. P. Stern, A. Hamfelt R. M. Watanabe and R. N. Bergman Erratum Comparison of the effect of GIP and GLP-1 (7-36amide) on insulin release from rat Number 4, April 1992 pancreatic islets E. G. Siegel, A. Schulze, W. E. Schmidt and The human renal 25-hydroxyvitamin D3-1la- W. Creutzfeldt hydroxylase: properties studied by isotope- dilution mass spectrometry Determinations of fasting plasma triglyceride levels: metabolism of hepatic and intestinal Y. Hagenfeldt and T. Berlin lipoproteins Uptake of chylomicron remmant retinyl esters J. A. Cortner, N.-A. Le, P. M. Coates, in human leukocytes in vivo M. J. Bennett and D. R. Cryer B. Skrede, R. Blomhoff, G. M. Maelandsmo, L. Ose, O. Myklebost and K. R. Norum Plasma apolipoprotein A-IV metabolism in patients with chronic renal disease Defect of epidermal 12(S)- H. Dieplinger, E.-M. Lobentanz, P. Konig, hydroxyeicosatetraenoic acid receptors in H. Graf, C. Sandholzer, E. Matthys, psoriasis M. Rosseneu and G. Utermann P. Arenberger, L. Kemény and T. Ruzicka Raised concentrations of carboxy terminal Incomplete suppression of hepatic glucose propeptide of type IV (basement membrane) production in non-insulin dependent diabetes procollagen (NC1) in serum and urine of mellitus measured with [6,6-7H2]glucose patients with glomerulonephritis enriched glucose infusion during K. Keller, Y. Lyreal Ser and D. Schuppan hyperinsulinaemic euglycaemic clamps J. K. Powrie, G. D. Smith, T. R. Hennessy, Thromboxane mediates glomerular F. Shojaee-Moradie, J. M. Kelly, P. H. Sénksen haemodynamics in a model of chronic and R. H. Jones glomerular disease F. Thaiss, M. J. Mihatsch, W. Schoeppe and Erythrocyte Lit/Na*t and Na*t/H*t exchange, R. A. K. Stahl cardiac anatomy and function in insulin- Alterations in lipoprotein density classes in dependent diabetics infantile visceral Leishmaniasis: presence of A. Semplicini, L. Lusiani, M. Marzola, apolipoprotein SAA G. Ceolotto, M. G. Mozzato, G. Zanette, E. D. Bekaert, E. Dole, D. Y. Dubois, V. Donadon, M. G. Stefanini, D. Zanuttini, M.-E. Bouma, J-F. Lontie, R. Kallel, A. C. Pessina C. L. Malmendier and M. Ayrault-Jarrier Identification of human urine of a natural Interleukin-8 and neutrophil activation in growth inhibitor for cells derived from solid acute pancreatitis paediatric tumours V. Gross, R. Andreesen, H.-G. Leser, M. Ceska, L. Schweigerer, K. Christeleit, G. Fleischmann, E. Liehl, M. Lausen, E. H. Farthmann and H. Adlercreutz, K. Wahdla, T. Hase, J. Schélmerich M. Schwab, R. Ludwig and T. Fotsis CONTENTS Central obesity and hyperinsulinaemia in Connective tissue response to major surgery women are associated with polymorphism in and postoperative infection the 5S’ flanking region of the human insulin H. Haukipuro, J. Melkko, L. Risteli, gene M. I. Kairaluoma and J. Risteli J. U. Weaver, P. G. Kopelman and G. A. Hitman The response of hepatic lipase and serum lipoproteins to acute hyprinsulinaemia in type Human recombinant CSa enhances 2 diabetes lipopolysaccharide-induced synthesis of C. Baynes, A. D. Henderson, W. Richmond, interleukin-6 by human monocytes D. G. Johnston and R. S. Elkeles V. Gross and T. Andus Intrinsic hepatic clearance of indocyanine Regional effects and clearance of endothelin-1 green in the pig: Dependence on plasma across pulmonary and spanchnic circulation protein concentration O. F. Wagner, H. Vierhapper, S. Gasic, P. Ott, S. Keiding and L. Bass P. Nowotny and W. Waldhdusl Cellular energetics in hypothyroid muscle Glucagon-like peptide-1 cells in the D. J. Taylor, B. Rajagopalan and G. K. Radda gastrointestinal tract and pancreas of rat, pig and man Bone mass of spine and forearm in R. Eissele, R. Géke, S. Willemer, osteoporosis and in German normals: influence H.-P. Harthus, H. Vermeer, R. Arnold and of sex, age and anthropometric parameters B. Goke C. Wiister, G. Duckeck, A. Ugurel, M. Lojen, H. W. Minne and R. Ziegler Effects of interferon alpha on insulin binding and glucose transport in human adipoctyes J. W. Kolaczynski, M.-R. Taskinen, H. Hilden, Number 6, June 1992 T. Kiviluoto, K. Cantell and V. A. Koivisto Classification of dynamical diseases by new mathematical tools: Application of multi- dimensional phase space analyses to the pulsatile secretion of parathyroid hormone Number 5, May 1992 H.-M. Harms, K. Prank, U. Brosa, E. Schlinke, O. Neubauer, G. Brabant and R. D. Hesch Eicosanoid levels in bronchoalveolar lavage fluid of young female smokers and non- Verapamil increases serum ionized calcium and smokers serum phosphate in patients with post-surgical F. J. Zijlstra, J. E. Vincent, W. M. Mol, hypoparathyroidism H. C. Hoogsteden, P. Th. W. Van Hal and G. Sjédén, M. Rosenqvist, J. Nordenstrém, R. C. Jongejan I. Bjorkhem, S. A. V. Eriksson and E. Kriegholm Affinity of anti-HBs antibody after hepatitis B vaccination Effects of cholestyramine and acipimox on M. Radkowski, T. Laskus, A. Goch and subfractions of plasma low density J. Slusarzcyk lipoprotein. Studies in normolipaemic and hypercholesterolaemic subjects Stimulation of neutrophils by insoluble B. A. Griffin, M. J. Caslake, A. Gaw, B. Yip, immunoglobulin aggregates from synovial fluid C. J. Packard and J. Shepherd of patients with rheumatoid arthritis J. J. Robinson, F. Watson, R. C. Bucknall and Functional and structural determinants of S. W. Edwards glomerulosclerosis in the fawn-hooded rat P. J. Westenend, Y. A. Nooyen, Haemodynamics and renal effects of J. A. Van Der Krogt, P. Van Brummelen and urodilation in healthy volunteers J. J. Weening M. Kentsch, D. Ludwig, C. Drummer, R. Gerzer and G. Miiller-Esch A TaqI polymorphism in the human interleukin-1f (IL-1) gene correlates with Effects of hypercholesterolemia on the IL-1 secretion in vitro nucleotide content in human blood cells F. Pociot, J. Molvig, L. Wogensen, H. Worsaae J. M. Felbel, E. A. Siess and N. Zoéliner and J. Nerup CONTENTS Identification of the defective NADPH-oxidase Evidence that human kidney produces a component in Chronic Granulomatous protein similar to lithostathine, the pancreatic Disease: a study of 57 European families inhibitor of CaCO; crystal growth C. Casimir, M. Chetty, M.-C. Bohler, J. M. Verdier, B. Dussol, P. Casanova, R. Garcia, A. Fischer, C. Griscelli, B. Johnson M. Daudons, P. Dupuy, P. Berthezene, and A. Segal R. Boistelle, Y. Berland and J. C. Dagorn Sustained high plasma 5-aminolaevulinic acid Inheritance of monoclonal rheumatoid factor concentration in a volunteer: no porpyric cross-reactive idiotypes in primary Sjégren’s symptoms syndrome (pSS). Comparative studies of a P. Mustajoki, K. Timonen, A. Gorchein, rabbit polyclonal anti-idiotype and 17109 A. M. Seppdldinen, E. Matikainen and R. monoclonal antiidiotype Tenhunen A. G. Tzioufas, D. S. Boumba, F. N. Skopouli, D. A. Carson and H. M. Moutsopoulos Importance of beta-adrenoceptor function in fat cells for lipid mobilization Patients with anticardiolipin antibodies with H. Wahrenberg, F. Lénnqvist, J. Hellmér and and without antiphospholipid syndrome: their P. Arner clinical features and /2-glycoprotein-1 plasma levels Influence of clinical findings, positional P. G. Vlachoyiannopoulos, S. A. Krills, manoeuvres, and systolic ankle arterial J. E. Hunt, M. N. Manoussakis and pressure on transcutaneous oxygen tension in H. M. Moutsopoulos peripheral arterial occlusive disease A. Scheffler, S. Eggert and H. Rieger Tumor necrosis factor alpha is associated with disease activity and the degree of anemia in Antibodies to Cathepsin G in Crohn’s disease patients with rheumatoid arthritis W. J. Mayet, E. Hermann, J. Finsterwalder, G. Vreugdenhil, B. Lowenberg, H. G. Van Eijk H. Reider, T. Poralla and K. H. Meyer Zum and A. J. G. Swaak Biischenfelde Effect of a somatostatin analogue, octreotide, Attempts to accelerate glucagon absorption on renal haemodynamics and albuminuria in effects of adding a vasodilator and of injection acromegalic patients using a ‘sprinkler’ needle R. P. F. Dullaart, S. Meijer, P. Marbach and K. L. Simmons and G. Williams W. J. Sluiter Letter to the Editor Number 8, August 1992 The Mack-Forster Award 1992 Number 7, July 1992 A. C. Nieuwenhuijzen Kruseman Editorial: Is cholesterol reduction always safe? 1992 Mack-Forster Award Lecture M. F. Oliver Review: Regulation of angiogenesis in vitro R. Montesano Review: Cell adhesion/signalling: biology and clinical applications Determinants of coronary effects of atrial M. W. Makgoba, A. Bernard and natriuretic factor in dogs M. E. Sanders G. Ertl, B. Bauer, P. Gaudron, M. Kolb and K. Kochsiek Bone mineral density measured by dual-energy X-ray absorptiometry in normal men Reappraisal of the role of insulin on sodium H. Kréger and K. Laitinen handling by the kidney: effect of intrarenal insulin infusion in the dog Human macrophages modulate the phenotype P. Briffeuil, T. Huynh Thu and J. Kolanowski of cultured rabbit aortic smooth muscle cells through secretion of platelet-derived growth Graves’ immunoglobulins and cytokines factor stimulate the expression of intercellular N. Morisaki, N. Koyama, M. Kawano, S. Mori, adhesion molecule-1 (ICAM-1) in cultured K. Umemiya, T. Koshikawa, Y. Saito and Graves’ orbital fibroblasts S. Yoshida A. E. Heufelder and R. S. Bahn CONTENTS Normal lipoprotein(a) concentrations and Correspondence between plasma mevalonic apolipoprotein(a) isoforms in patients with acid levels and deuterium uptake in measuring insulin-dependent diabetes mellitus human cholesterol synthesis I. C. Klausen, E. Berg Schmidt, H. H. Lervang, P. J. H. Jones, A. S. Pappu, D. R. Illingworth L. U. Gerdes, J. Ditzel and O. Faergeman and C. A. Leitch Bone mass and biochemical parameters of Pancreatic and pituitary hormonal responses to bone metabolism in men with spinal insulin-induced hypoglycaemia during osteoporosis muscarinic cholinergic blockade in man H. Resch, P. Pietschmann, W. Woloszczuk, B. M. Fisher, D. A. Hepburn, B. M. Frier, E. Krexner, P. Bernecker and R. Willvonseder J. J. Morton, G. H. Beastall, C. E. Gray and K. D. Buchanan Nutritional behaviour and quality of life during oncological polychemotherapy: Results Experimental variations in renovascular of a prospective study on the efficacy of oral resistance in normal man as detected by means nutrition therapy in patients with acute of ultrasound leukaemia M. Bardelli, G. Jensen, R. Volkmann, G. Ollenschlager, W. Thomas, K. Konkol, K. Caidahl and M. Aurell V. Diehl and E. Roth Effect of lipid A on the deformability, A comparison of octreotide delivered by membrane rigidity and geometry of human continuous subcutaneous infusion with adult red blood cells intermittent injection in the treatment of J. M. B. Péschl and O. Linderkamp acromegaly R. A. James, M. C. White, S. Chatterjee, Colchicine analogues: Effect on H. Marciaj and P. Kendall-Taylor amyloidogenesis in a murine model and, in vitro, on polymorphonuclear leukocytes Renal reserve filtration capacity in growth B. Wolach, M. Gotfried, A. Jedeikin, hormone deficient subjects M. Lishner, A. Brossi and M. Ravid R. P. F. Dullaart, S. Meijer, P. Marbach and W. J. Sluiter Rapid Communication: Role of hepatitis C virus infection in German patients with fulminant and subacute hepatic failure Number 10, October 1992 L. Theilmann, C. Solbach, U. Toex, H. M. Miller, E. Pfaff, G. Otto and T. Goeser Commentary: Abnormal neuroendocrine immune communications in patients with rheumatoid arthritis Number 9, September 1992 I. C. Chikanza, G. Chrousos and G. S. Panayi Review: Current concepts in the Increased tissue concentrations of the gastrin pathophysiology of hepatic encephalopathy precursor in patients treated with omeprazole P. Ferenci, A. Piispék and P. Steindl J. Nemeth, A. Varro, J.Bridson, R. Walker and G. J. Dockray Insulin sensitivity and secretion in healthy elderly human subjects with ‘abnormal’ glucose Supplementation with n-3 fatty acids reduces tolerance triglycerides but increases PAI-1 in non- D. L. Broughton, J. Webster and R. Taylor insulin-dependent diabetes mellitus M. Boberg, T. Pollare, A. Siegbahn and Increased GPII/IIIA expression and altered B. Vessby DNA-ploidy pattern in megakaryocytes of diabetic BB-rats Late-onset congenital adrenal hyperplasia in D. Tschépe, B. Schwippert, B. Schettler, women with hirsutism U. Kiesel, H. Rothe, P. Roesen and F. A. Gries M. A. Arnaout Severe type III hyperlipoproteinemia In vitro immune modulation of associated with unusual apolipoprotein El polymorphonuclear leukocyte adhesiveness by phenotype and ¢1/‘null’ genotype sodium fluoride G. Feussner, H. Funke, W. Weng, G. Assmann, J. L. Gomez-Ubric, J. Lieébana, J. Gutiérrez and K. J. Lackner and R. Ziegler A. Castillo Vill CONTENTS Haemodynamic and renal effects of urodilatin The glucoregulatory and antilipolytic actions bolus injections in patients with congestive of insulin in abdominal obesity with normal or heart failure impaired glucose tolerance: an in vivo and M. Kentsch, D. Ludwig, C. Drummer, R. Gerzer in vitro study and G. Miiller-Esch P. Cavallo-Perin, A. Bruno, M. Cassader, L. Cesco, G. Gruden and G. Pagano Antibody mediated enhancement of HIV-1 infection of an EBV transformed Bc ell line is Leukotriene By, level in stimulated blood CD4 dependent neutrophils and alveolar macrophages from H. S. L. M. Nottet, I. Janse, N. M. De Vos, healthy and asthmatic subjects. Effect of beta-2 L. J. Bakker, M. R. Visser and J. Verhoef agonist therapy Y. Pacheco, R. Hosni, B. Chabannes, Transforming growth factor alpha and atrial F. Gormand, P. Molliere, M. Grosclaude, natriuretic peptide in white adipose tissue D. Piperno, M. Lagarde and M. Perrin-Fayolle depots in rats D. L. Crandall, G. Gordon, H. E. Herzlinger, Prolonged sleep deprivation induced disturbed B. D. Saunders, R. C. Zolotor, P. Cervoni and liver functions, serum lipid levels and J. G. Kral hyperphosphatemia Y. Ilan G. Martinowitz, O. Abramsky, Circulating inhibitor of interleukin 1| activity in G. Glazer and P. Lavie patients with chronic renal diseases Z. Rami¢, N. Dimkovié, Lj. Djukanovic¢, Bile acid active and passive ileal transport in M. Lazi¢, S. Stepanovié, M. Simié and the rabbit: effect of luminal stirring M. L. Lukic R. Aldini, A. Roda, P. L. Lenzi, G. Ussia, M. C. Vaccari, G. Mazzella, D. Festi, The effects of dietary supplementation with n-3 F. Bazzoli, G. Galetti, S. Casanova, polyunsaturated fatty acids in patients with M. Montagnani and E. Roda rheumatoid arthritis: a randomized, double blind trial Multi-frequency bioelectrical impedance G. L. Nielsen, K. L. Faarvang, B. S. Thompsen, augments the diagnosis and management of K. L. Teglbjaerg, L. T. Jensen, T. M. Hansen, lymphoedema in post-mastectomy patients H. H. Lervang, E. B. Schmidt, J. Dyerberg and L. C. Ward, I. H. Bunce, B. H. Cornish, E. Ernst B. R. Mirolo, B. J. Thomas and L. C. Jones Rapid Communication: The critical role of Early diagnosis of the multiple endocrine magnesium ions in osteoclastmatrix neoplasia type 2 syndrome: consensus interaction: implications for divalent cations in statement the study of osteoclastic adhesion molecules C. Calmettes, B. A. J. Ponder, J. A. Fischer, and bone resorption F. Raue and The Members of the European M. Makgoba and H. K. Datta Community Concerted Action: Medullary Thyroid Carcinoma Number 11, November 1992 Review: T-lymphocytes and the pathogenesis of type | (insulin-dependent) diabetes mellitus Number 12, December 1992 B. O. Roep and R. R. P. De Vries Conference Report: New horizons in the Surfactant protein A (SP-A) is decreased in pathogenesis of coronary heart disease acute parenchymal lung injury associated with M. Oliver polytrauma U. Pison, U. Obertacke, W. Seeger and Commentary: Prediction of bone loss in S. Hawgood postmenopausal women A. Blumsohn and R. Eastell Plasma lipids affect maximum velocity not sodium affinity of human sodium-lithium Can urinary pyridinium crosslinks and urinary countertransport: distinction from essential oestrogens predict bone mass and rate of bone hypertension loss after the menopause P. A. Rutherford, T. H. Thomas, M. F. Laker P. A. Mole, M. H. Walkinshaw, S. P. Robins and R. Wilkinson and C. R. Paterson CONTENTS Autoantibodies to insulin have similar affinity Compositional analysis of the collagenous to that of antibodies to exogenous but lower bone matrix. A study on adult normal and binding capacity osteopenic bone tissue P. Vahdsalo B. Batge, J. Diebold, H. Stein, M. Bodo and P. K. Miiller Effect of intravenous polyunsaturated phosphatidylcholine infusion on insulin Post-prandial lipoprotein metabolism in receptor processing and lipid composition of nephrotic syndrome erythrocytes in patients with liver cirrhosis G. L. Warwick, C. J. Packard, J. P. Stewart, A. Cantafora, R. Masella, M. Angelico, T. D. G. Watson, L. Burns, J. M. Boulton-Jones C. Gandin, R. J. Blount and S. W.Peterson and J. Shepherd Anti-neutrophil cytosplasm antibodies, anti- Short-term indomethacin administration does GBM antibodies and anti-dsDNA antibodies not impair excretion of acute potassium load in in glomerulonephritis humans P. Bygren, N. Rasmussen, B. Isaksson and M. Van Buren, H. J. M. Van Rijn and J. Wieslander H. A. Koomans Effects of the new somatostatin analogue (BIM Postprandial control of gallbladder contraction 23014) on blood glucose homeostasis in normal and exocrine pancreatic secretion in man men C. Beglinger, P. Hildebrand, G. Adler, J. M. Kuhn, C. Basin, M. Mollard, B. Werth, H. Luo, F. Delco and K. Gyr B. De Rouge, B. Schatz and L. M. Wolf Notice Extra-hepatic cholestasis determines a reversible increase of glycoproteic tumour Author index markers in benign and malignant diseases D. Basso, T. Meggiato, C. Fabris, M. Plebani, Keyword index P. Fogar, M. P. Panozzo and G. Del Favero