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Essentials of Clinical Infectious Diseases PDF

385 Pages·2013·18.44 MB·English
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Essentials of Clinical Infectious Diseases Essentials of Clinical Infectious Diseases William F. Wright, DO, MPH Assistant Professor Division of Infectious Diseases Department of Medicine University of Maryland School of Medicine Baltimore, Maryland New York Acquisitions Editor: Beth Barry Compositor: Amnet Systems Pvt. Ltd. Visit our website at www.demosmedpub.com ISBN: 9781936287918 e-book ISBN: 9781617051531 © 2013 Demos Medical Publishing, LLC. All rights reserved. This book is protected by copyright. No part of it may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher. Medicine is an ever-changing science. Research and clinical experience are continually expanding our knowledge, in particular our understanding of proper treatment and drug therapy. The authors, editors, and publisher have made every effort to ensure that all information in this book is in accordance with the state of knowledge at the time of production of the book. Nevertheless, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, express or implied, with respect to the contents of the publication. Every reader should examine carefully the package inserts accompanying each drug and should carefully check whether the dosage schedules mentioned therein or the contraindications stated by the manufacturer differ from the statements made in this book. Such examination is particularly important with drugs that are either rarely used or have been newly released on the market. Library of Congress Cataloging-in-Publication Data Wright, William F. (William Floyd) Essentials of clinical infectious diseases / by William F. Wright. p. ; cm. Includes bibliographical references and index. ISBN 978-1-936287-91-8 (hardcover : alk. paper) -- ISBN 978-1-61705-153-1 (e-book) I. Title. [DNLM: 1. Bacterial Infections—diagnosis. 2. Bacterial Infections—drug therapy. 3. Anti-Infective Agents—therapeutic use. 4. Communicable Diseases—diagnosis. 5. Communicable Diseases—drug therapy. 6. Infection. WC 200] 614.597—dc23 2012042844 Special discounts on bulk quantities of Demos Medical Publishing books are available to corporations, professional associations, pharmaceutical companies, health care organizations, and other qualifying groups. For details, please contact: Special Sales Department Demos Medical Publishing, LLC 11 West 42nd Street, 15th Floor New York, NY 10036 Phone: 800-532-8663 or 212-683-0072 Fax: 212-941-7842 E-mail: [email protected] Printed in the United States of America by Gasch Printing. 13 14 15 16 / 5 4 3 2 1 This book is dedicated to my loving and beautiful wife, Courtney. Contents Contributors xi Preface xiii Acknowledgments xv I. IntrODuCtIOn tO CLInICaL InFECtIOus DIsEasEs 1. Introduction to Infectious Disease 1 William F. Wright Bruce L. Gilliam 2. Introduction to antimicrobial agents 3 Emily L. Heil Neha U. Sheth William F. Wright 3. Introduction to Medical Microbiology 30 Nicole M. Parrish Stefan Riedel II. aPPrOaCH tO FEVEr anD LEukOCytOsIs 4. Fever of unknown Origin 35 William F. Wright 5. Leukocytosis 44 William F. Wright III. aPPrOaCH tO BLOODstrEaM anD CarDIOVasCuLar InFECtIOns 6. Endocarditis 51 Jennifer Husson William F. Wright 7. Myocarditis 59 William F. Wright 8. nonvalvular Intravascular Device Infections 65 William F. Wright 9. Infections Involving Intravascular Catheters 70 Eric Cox Kerri A. Thom viii Contents IV. aPPrOaCH tO PuLMOnary InFECtIOns 10. Pneumonia 77 Ulrike K. Buchwald Devang M. Patel 11. Empyema 89 Gonzalo Luizaga Luciano Kapelusznik William F. Wright 12. Lung abscess 96 Adrian Majid Ulrike K. Buchwald Devang M. Patel 13. tuberculosis 102 David W. Keckich Ulrike K. Buchwald V. aPPrOaCH tO GastrOIntEstInaL InFECtIOns 14. Diverticulitis 113 William F. Wright 15. appendicitis 119 William F. Wright 16. Pancreatic Infections 125 William F. Wright 17. Peritonitis 130 William F. Wright 18. Infectious Diarrhea 137 William F. Wright 19. Clostridium difficile Colitis 144 Ryan S. Arnold William F. Wright VI. aPPrOaCH tO HEPatOBILIary InFECtIOns 20. Cholecystitis 151 William F. Wright 21. acute Cholangitis 156 William F. Wright VII. aPPrOaCH tO HEPatIC InFECtIOns 22. Hepatic abscess 161 William F. Wright 23. Hepatitis a 167 William F. Wright Contents ix 24. Hepatitis B 172 Luciano Kapelusznik Rohit Talwani William F. Wright 25. Hepatitis C 179 Rohit Talwani Luciano Kapelusznik William F. Wright VIII. aPPrOaCH tO rEnaL-urInary InFECtIOns 26. urinary tract Infections 185 Janaki C. Kuruppu William F. Wright 27. Pyelonephritis and renal abscess 191 Jason Bailey Janaki C. Kuruppu William F. Wright 28. Catheter-related urinary tract Infections 199 Clare Rock Kerri A. Thom William F. Wright IX. aPPrOaCH tO nEurOLOGICaL InFECtIOns 29. Meningitis 205 William F. Wright 30. Infectious Encephalitis 212 William F. Wright 31. Brain abscess 218 William F. Wright X. aPPrOaCH tO OrtHOPEDIC-rELatED InFECtIOns 32. Osteomyelitis 225 William F. Wright 33. septic arthritis 233 William F. Wright 34. Prosthetic Joint Infections 241 William F. Wright XI. aPPrOaCH tO skIn anD sOFt-tIssuE InFECtIOns 35. Cellulitis 251 William F. Wright 36. necrotizing skin and soft-tissue Infections 257 William F. Wright 37. Diabetic Foot Infections 261 William F. Wright

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This practical handbook provides readers with a quick but comprehensive overview of the major infectious disease topics and clinical approach to diagnosis and management. Covering the core areas of importance to students, residents, fellows, and practitioners in any discipline, the book presents a s
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